TreeWAS – Variant ID: rs707896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
I10 Essential (primary) hypertension	0.000	0.002	0.998
K70-K77 Diseases of liver	0.000	0.318	0.682
K75 Other inflammatory liver diseases	0.000	0.319	0.681
K70 Alcoholic liver disease	0.000	0.324	0.676
K75.4 Autoimmune hepatitis	0.000	0.351	0.649
K75.9 Inflammatory liver disease, unspecified	0.000	0.365	0.635
K70.9 Alcoholic liver disease, unspecified	0.000	0.373	0.627
K74 Fibrosis and cirrhosis of liver	0.000	0.375	0.625
K70.4 Alcoholic hepatic failure	0.000	0.386	0.614
K70.3 Alcoholic cirrhosis of liver	0.000	0.409	0.591
E83 Disorders of mineral metabolism	0.000	0.411	0.589
K74.6 Other and unspecified cirrhosis of liver	0.000	0.416	0.584
K75.8 Other specified inflammatory liver diseases	0.000	0.427	0.573
K76 Other diseases of liver	0.000	0.429	0.571
K75.0 Abscess of liver	0.000	0.439	0.561
K73 Chronic hepatitis, not elsewhere classified	0.000	0.451	0.549
K76.9 Liver disease, unspecified	0.000	0.454	0.546
K74.0 Hepatic fibrosis	0.000	0.457	0.543
K72 Hepatic failure, not elsewhere classified	0.000	0.458	0.542
K70.0 Alcoholic fatty liver	0.000	0.481	0.519
K76.6 Portal hypertension	0.000	0.503	0.497
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.503	0.497
K70.1 Alcoholic hepatitis	0.000	0.507	0.493
K77 Liver disorders in diseases classified elsewhere	0.000	0.511	0.489
K71 Toxic liver disease	0.000	0.511	0.489
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.511	0.488
K75.2 Nonspecific reactive hepatitis	0.000	0.511	0.488
K75.1 Phlebitis of portal vein	0.000	0.511	0.488
E83.3 Disorders of phosphorus metabolism	0.000	0.521	0.479
K72.0 Acute and subacute hepatic failure	0.000	0.537	0.463
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.539	0.461
E83.4 Disorders of magnesium metabolism	0.000	0.550	0.450
K74.4 Secondary biliary cirrhosis	0.000	0.551	0.448
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.551	0.448
K74.1 Hepatic sclerosis	0.000	0.551	0.448
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.578	0.422
E83.8 Other disorders of mineral metabolism	0.000	0.578	0.422
E83.2 Disorders of zinc metabolism	0.000	0.578	0.422
E83.0 Disorders of copper metabolism	0.000	0.578	0.422
K76.5 Hepatic veno-occlusive disease	0.000	0.590	0.409
K76.4 Peliosis hepatis	0.000	0.590	0.409
K76.3 Infarction of liver	0.000	0.590	0.409
K76.2 Central haemorrhagic necrosis of liver	0.000	0.590	0.409
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.606	0.393
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.606	0.393
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.606	0.393
K72.1 Chronic hepatic failure	0.000	0.611	0.389
K76.7 Hepatorenal syndrome	0.000	0.620	0.380
K73.9 Chronic hepatitis, unspecified	0.000	0.620	0.379
K74.3 Primary biliary cirrhosis	0.000	0.626	0.374
K74.5 Biliary cirrhosis, unspecified	0.000	0.638	0.362
E83.5 Disorders of calcium metabolism	0.000	0.643	0.357
K76.1 Chronic passive congestion of liver	0.000	0.645	0.354
K71.9 Toxic liver disease, unspecified	0.000	0.649	0.351
K71.8 Toxic liver disease with other disorders of liver	0.000	0.649	0.351
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.649	0.351
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.649	0.351
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.649	0.351
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.649	0.351
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.649	0.351
K71.2 Toxic liver disease with acute hepatitis	0.000	0.649	0.351
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.649	0.351
K71.0 Toxic liver disease with cholestasis	0.000	0.649	0.351
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.649	0.351
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.649	0.351
K72.9 Hepatic failure, unspecified	0.000	0.651	0.349
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.702	0.298
I10-I15 Hypertensive diseases	0.000	0.715	0.285
E80.4 Gilbert's syndrome	0.000	0.767	0.233
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.783	0.217
I11 Hypertensive heart disease	0.000	0.786	0.214
E70-E90 Metabolic disorders	0.000	0.795	0.205
I13 Hypertensive heart and renal disease	0.000	0.795	0.204
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.822	0.178
I12 Hypertensive renal disease	0.000	0.822	0.178
E73 Lactose intolerance	0.000	0.832	0.168
E80.6 Other disorders of bilirubin metabolism	0.000	0.841	0.159
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.844	0.155
E80.5 Crigler-Najjar syndrome	0.000	0.844	0.155
E80.3 Defects of catalase and peroxydase	0.000	0.844	0.155
E80.2 Other porphyria	0.000	0.844	0.155
E80.1 Porphyria cutanea tarda	0.000	0.844	0.155
E80.0 Hereditary erythropoietic porphyria	0.000	0.844	0.155
E74 Other disorders of carbohydrate metabolism	0.000	0.850	0.150
K76.8 Other specified diseases of liver	0.000	0.851	0.149
I12.9 Hypertensive renal disease without renal failure	0.000	0.851	0.149
E84 Cystic fibrosis	0.000	0.853	0.147
E77 Disorders of glycoprotein metabolism	0.000	0.853	0.147
E76 Disorders of glycosaminoglycan metabolism	0.000	0.853	0.147
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.853	0.147
E72 Other disorders of amino-acid metabolism	0.000	0.853	0.147
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.853	0.147
E70 Disorders of aromatic amino-acid metabolism	0.000	0.853	0.147
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.853	0.147
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.853	0.147
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.853	0.147
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.853	0.147
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.853	0.147
E79 Disorders of purine and pyrimidine metabolism	0.000	0.854	0.146
E73.9 Lactose intolerance, unspecified	0.000	0.858	0.142
I15 Secondary hypertension	0.000	0.864	0.136
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.870	0.130
E73.8 Other lactose intolerance	0.000	0.879	0.120
E73.1 Secondary lactase deficiency	0.000	0.879	0.120
E73.0 Congenital lactase deficiency	0.000	0.879	0.120
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.889	0.110
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.892	0.107
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.892	0.107
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.892	0.107
E74.2 Disorders of galactose metabolism	0.000	0.892	0.107
E74.1 Disorders of fructose metabolism	0.000	0.892	0.107
E74.0 Glycogen storage disease	0.000	0.892	0.107
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.894	0.105
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.894	0.105
E70.3 Albinism	0.000	0.894	0.105
E70.2 Disorders of tyrosine metabolism	0.000	0.894	0.105
E70.1 Other hyperphenylalaninaemias	0.000	0.894	0.105
E70.0 Classical phenylketonuria	0.000	0.894	0.105
E71.3 Disorders of fatty-acid metabolism	0.000	0.894	0.105
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.894	0.105
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.894	0.105
E71.0 Maple-syrup-urine disease	0.000	0.894	0.105
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.894	0.105
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.894	0.105
E72.5 Disorders of glycine metabolism	0.000	0.894	0.105
E72.4 Disorders of ornithine metabolism	0.000	0.894	0.105
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.894	0.105
E72.2 Disorders of urea cycle metabolism	0.000	0.894	0.105
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.894	0.105
E72.0 Disorders of amino-acid transport	0.000	0.894	0.105
E75.6 Lipid storage disorder, unspecified	0.000	0.894	0.105
E75.5 Other lipid storage disorders	0.000	0.894	0.105
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.894	0.105
E75.3 Sphingolipidosis, unspecified	0.000	0.894	0.105
E75.2 Other sphingolipidosis	0.000	0.894	0.105
E75.1 Other gangliosidosis	0.000	0.894	0.105
E75.0 GM2 gangliosidosis	0.000	0.894	0.105
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.894	0.105
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.894	0.105
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.894	0.105
E76.2 Other mucopolysaccharidoses	0.000	0.894	0.105
E76.1 Mucopolysaccharidosis, type II	0.000	0.894	0.105
E76.0 Mucopolysaccharidosis, type I	0.000	0.894	0.105
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.894	0.105
E77.8 Other disorders of glycoprotein metabolism	0.000	0.894	0.105
E77.1 Defects in glycoprotein degradation	0.000	0.894	0.105
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.894	0.105
E84.9 Cystic fibrosis, unspecified	0.000	0.894	0.105
E84.8 Cystic fibrosis with other manifestations	0.000	0.894	0.105
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.894	0.105
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.894	0.105
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.895	0.105
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.895	0.105
E79.1 Lesch-Nyhan syndrome	0.000	0.895	0.105
E88 Other metabolic disorders	0.000	0.895	0.105
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.896	0.103
I15.8 Other secondary hypertension	0.000	0.902	0.097
I15.2 Hypertension secondary to endocrine disorders	0.000	0.902	0.097
I15.0 Renovascular hypertension	0.000	0.902	0.097
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.907	0.093
I63.9 Cerebral infarction, unspecified	0.000	0.912	0.088
I67.1 Cerebral aneurysm, nonruptured	0.000	0.915	0.085
I63 Cerebral infarction	0.000	0.915	0.085
I67 Other cerebrovascular diseases	0.000	0.915	0.085
I60-I69 Cerebrovascular diseases	0.000	0.917	0.083
E89.3 Postprocedural hypopituitarism	0.000	0.918	0.082
I69 Sequelae of cerebrovascular disease	0.000	0.919	0.081
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.922	0.078
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.924	0.076
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.924	0.076
E88.8 Other specified metabolic disorders	0.000	0.925	0.075
E88.3 Tumour lysis syndrome	0.000	0.925	0.075
I15.9 Seconday hypertension, unspecified	0.001	0.925	0.074
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.927	0.073
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.927	0.073
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.928	0.072
I67.9 Cerebrovascular disease, unspecified	0.000	0.929	0.071
E88.2 Lipomatosis, not elsewhere classified	0.000	0.929	0.071
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.929	0.071
I15.1 Hypertension secondary to other renal disorders	0.001	0.930	0.069
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.933	0.066
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.933	0.066
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.933	0.066
E89.5 Postprocedural testicular hypofunction	0.000	0.933	0.066
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.934	0.066
E89.4 Postprocedural ovarian failure	0.000	0.935	0.065
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.935	0.065
E88.9 Metabolic disorder, unspecified	0.000	0.937	0.063
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.937	0.063
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.937	0.063
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.938	0.062
E85 Amyloidosis	0.001	0.939	0.060
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.939	0.061
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.939	0.061
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.939	0.061
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.939	0.061
I67.5 Moyamoya disease	0.000	0.939	0.061
I67.4 Hypertensive encephalopathy	0.000	0.939	0.061
I67.3 Progressive vascular leukoencephalopathy	0.000	0.939	0.061
M19.94 Arthrosis, unspecified (Hand)	0.060	0.940	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.940	0.060
I67.2 Cerebral atherosclerosis	0.000	0.940	0.060
E78.1 Pure hyperglyceridaemia	0.000	0.941	0.059
E89.1 Postprocedural hypoinsulinaemia	0.000	0.942	0.058
I60 Subarachnoid haemorrhage	0.000	0.943	0.057
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.945	0.055
E78.5 Hyperlipidaemia, unspecified	0.000	0.945	0.055
I67.8 Other specified cerebrovascular diseases	0.000	0.947	0.053
E78.6 Lipoprotein deficiency	0.000	0.947	0.053
E78.3 Hyperchylomicronaemia	0.000	0.947	0.053
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.947	0.052
I63.8 Other cerebral infarction	0.000	0.949	0.051
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.950	0.050
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.950	0.050
E78.8 Other disorders of lipoprotein metabolism	0.000	0.952	0.048
E89.2 Postprocedural hypoparathyroidism	0.000	0.952	0.048
Chapter IX Diseases of the circulatory system	0.000	0.952	0.048
I61 Intracerebral haemorrhage	0.000	0.952	0.048
I12.0 Hypertensive renal disease with renal failure	0.000	0.953	0.047
E78.4 Other hyperlipidaemia	0.000	0.955	0.044
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.956	0.043
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.956	0.043
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.956	0.043
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.957	0.043
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.957	0.043
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.957	0.043
I68.0 Cerebral amyloid angiopathy	0.000	0.957	0.043
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.957	0.043
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.958	0.042
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.958	0.042
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.959	0.041
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.959	0.041
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.959	0.041
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.960	0.040
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.960	0.039
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.960	0.039
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.960	0.039
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.960	0.039
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.960	0.039
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.960	0.039
I69.3 Sequelae of cerebral infarction	0.000	0.961	0.039
E85.3 Secondary systemic amyloidosis	0.001	0.961	0.037
I62 Other nontraumatic intracranial haemorrhage	0.000	0.963	0.037
E85.8 Other amyloidosis	0.001	0.963	0.036
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.963	0.037
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.964	0.036
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.964	0.036
E85.9 Amyloidosis, unspecified	0.001	0.964	0.035
I61.8 Other intracerebral haemorrhage	0.000	0.964	0.036
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.964	0.035
I60.8 Other subarachnoid haemorrhage	0.000	0.965	0.035
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.965	0.035
O03 Spontaneous abortion	0.035	0.965	0.000
E87.3 Alkalosis	0.000	0.965	0.035
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.965	0.035
O70 Perineal laceration during delivery	0.035	0.965	0.000
O70.1 Second degree perineal laceration during delivery	0.035	0.965	0.000
I00-I02 Acute rheumatic fever	0.000	0.965	0.034
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.966	0.034
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.966	0.034
O03.4 Incomplete, without complication	0.034	0.966	0.000
O03.9 Complete or unspecified, without complication	0.034	0.966	0.000
O70.0 First degree perineal laceration during delivery	0.034	0.966	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.967	0.033
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.967	0.033
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.969	0.031
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.970	0.030
O03.8 Complete or unspecified, with other and unspecified complications	0.030	0.970	0.000
O60-O75 Complications of labour and delivery	0.030	0.970	0.000
I83 Varicose veins of lower extremities	0.000	0.971	0.029
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.971	0.028
Chapter XV Pregnancy, childbirth and the puerperium	0.028	0.972	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.028	0.972	0.000
O00-O08 Pregnancy with abortive outcome	0.028	0.972	0.000
O62 Abnormalities of forces of labour	0.028	0.972	0.000
O70.2 Third degree perineal laceration during delivery	0.028	0.972	0.000
O62.2 Other uterine inertia	0.027	0.973	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.973	0.027
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.973	0.027
I62.1 Nontraumatic extradural haemorrhage	0.000	0.973	0.027
O24 Diabetes mellitus in pregnancy	0.027	0.973	0.000
I86 Varicose veins of other sites	0.000	0.973	0.027
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.973	0.027
E87.4 Mixed disorder of acid-base balance	0.000	0.973	0.026
I86.1 Scrotal varices	0.000	0.974	0.026
O03.3 Incomplete, with other and unspecified complications	0.026	0.974	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.026	0.974	0.000
O80-O84 Delivery	0.026	0.974	0.000
O03.7 Complete or unspecified, complicated by embolism	0.025	0.974	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.025	0.974	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.025	0.974	0.000
O03.2 Incomplete, complicated by embolism	0.025	0.974	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.025	0.974	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.975	0.025
O70.3 Fourth degree perineal laceration during delivery	0.025	0.975	0.000
I02 Rheumatic chorea	0.000	0.975	0.025
I01 Rheumatic fever with heart involvement	0.000	0.975	0.025
I00 Rheumatic fever without mention of heart involvement	0.000	0.975	0.025
O68 Labour and delivery complicated by foetal stress [distress]	0.024	0.976	0.000
E85.4 Organ-limited amyloidosis	0.002	0.976	0.022
O81 Single delivery by forceps and vacuum extractor	0.024	0.976	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.024	0.976	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.976	0.024
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.976	0.024
O62.0 Primary inadequate contractions	0.023	0.976	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.023	0.976	0.000
O70.9 Perineal laceration during delivery, unspecified	0.023	0.977	0.000
O66 Other obstructed labour	0.023	0.977	0.000
I86.4 Gastric varices	0.000	0.977	0.023
E87.2 Acidosis	0.000	0.977	0.023
O61 Failed induction of labour	0.023	0.977	0.000
O28 Abnormal findings on antenatal screening of mother	0.022	0.977	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.977	0.023
I27 Other pulmonary heart diseases	0.000	0.978	0.022
O74 Complications of anaesthesia during labour and delivery	0.022	0.978	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.022	0.978	0.000
E87.6 Hypokalaemia	0.000	0.978	0.022
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.022	0.978	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.022	0.978	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.022	0.978	0.000
O20 Haemorrhage in early pregnancy	0.022	0.978	0.000
O85-O92 Complications predominantly related to the puerperium	0.022	0.978	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.979	0.021
O60 Preterm delivery	0.021	0.979	0.000
I85 Oesophageal varices	0.000	0.979	0.021
O81.3 Other and unspecified forceps delivery	0.021	0.979	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.021	0.979	0.000
O81.0 Low forceps delivery	0.021	0.979	0.000
O62.1 Secondary uterine inertia	0.021	0.979	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.021	0.979	0.000
O21 Excessive vomiting in pregnancy	0.021	0.979	0.000
O82 Single delivery by Caesarean section	0.021	0.979	0.000
O29 Complications of anaesthesia during pregnancy	0.020	0.980	0.000
O25 Malnutrition in pregnancy	0.020	0.980	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.020	0.980	0.000
O07 Failed attempted abortion	0.020	0.980	0.000
O06 Unspecified abortion	0.020	0.980	0.000
O05 Other abortion	0.020	0.980	0.000
O01 Hydatidiform mole	0.020	0.980	0.000
O62.9 Abnormality of forces of labour, unspecified	0.020	0.980	0.000
O62.8 Other abnormalities of forces of labour	0.020	0.980	0.000
A49 Bacterial infection of unspecified site	0.000	0.980	0.020
O26.9 Pregnancy-related condition, unspecified	0.020	0.980	0.000
O22 Venous complications in pregnancy	0.020	0.980	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.020	0.980	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.020	0.980	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.980	0.020
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.980	0.020
A49.1 Streptococcal infection, unspecified	0.000	0.980	0.020
I86.3 Vulval varices	0.000	0.980	0.019
I86.2 Pelvic varices	0.000	0.980	0.019
I86.0 Sublingual varices	0.000	0.980	0.019
O24.3 Pre-existing diabetes mellitus, unspecified	0.019	0.980	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.019	0.980	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.019	0.980	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.980	0.020
O71 Other obstetric trauma	0.019	0.981	0.000
O26.2 Pregnancy care of habitual aborter	0.019	0.981	0.000
O81.4 Vacuum extractor delivery	0.019	0.981	0.000
O62.3 Precipitate labour	0.019	0.981	0.000
O73 Retained placenta and membranes, without haemorrhage	0.019	0.981	0.000
O84 Multiple delivery	0.019	0.981	0.000
O83 Other assisted single delivery	0.019	0.981	0.000
O86 Other puerperal infections	0.019	0.981	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.982	0.018
I01.8 Other acute rheumatic heart disease	0.000	0.982	0.018
I01.2 Acute rheumatic myocarditis	0.000	0.982	0.018
I01.1 Acute rheumatic endocarditis	0.000	0.982	0.018
I01.0 Acute rheumatic pericarditis	0.000	0.982	0.018
I02.9 Rheumatic chorea without heart involvement	0.000	0.982	0.018
I02.0 Rheumatic chorea with heart involvement	0.000	0.982	0.018
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.982	0.018
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.018	0.982	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.018	0.982	0.000
O20.8 Other haemorrhage in early pregnancy	0.018	0.982	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.018	0.982	0.000
O61.0 Failed medical induction of labour	0.018	0.982	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.018	0.982	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.018	0.982	0.000
O81.2 Mid-cavity forceps with rotation	0.018	0.982	0.000
O81.1 Mid-cavity forceps delivery	0.018	0.982	0.000
O23 Infections of genito-urinary tract in pregnancy	0.018	0.982	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.018	0.982	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.018	0.982	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.982	0.017
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.982	0.017
I86.8 Varicose veins of other specified sites	0.000	0.982	0.017
I85.0 Oesophageal varices with bleeding	0.000	0.982	0.018
O66.4 Failed trial of labour, unspecified	0.017	0.982	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.982	0.018
O72 Postpartum haemorrhage	0.017	0.982	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.017	0.983	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.983	0.017
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.017	0.983	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.017	0.983	0.000
O26.5 Maternal hypotension syndrome	0.017	0.983	0.000
O26.4 Herpes gestationis	0.017	0.983	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.017	0.983	0.000
O26.1 Low weight gain in pregnancy	0.017	0.983	0.000
O26.0 Excessive weight gain in pregnancy	0.017	0.983	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.017	0.983	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.983	0.017
O20.0 Threatened abortion	0.017	0.983	0.000
O66.9 Obstructed labour, unspecified	0.017	0.983	0.000
O66.8 Other specified obstructed labour	0.017	0.983	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.017	0.983	0.000
O66.2 Obstructed labour due to unusually large foetus	0.017	0.983	0.000
O66.1 Obstructed labour due to locked twins	0.017	0.983	0.000
O14.9 Preeclampsia, unspecified	0.017	0.983	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.017	0.983	0.000
O85 Puerperal sepsis	0.016	0.983	0.000
O61.9 Failed induction of labour, unspecified	0.016	0.983	0.000
O61.8 Other failed induction of labour	0.016	0.983	0.000
O61.1 Failed instrumental induction of labour	0.016	0.983	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.017	0.983	0.000
I88 Nonspecific lymphadenitis	0.000	0.983	0.016
O67.9 Intrapartum haemorrhage, unspecified	0.016	0.984	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.016	0.984	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.016	0.984	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.016	0.984	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.016	0.984	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.016	0.984	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.016	0.984	0.000
O82.9 Delivery by Caesarean section, unspecified	0.016	0.984	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.984	0.016
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.016	0.984	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.016	0.984	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.016	0.984	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.016	0.984	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.016	0.984	0.000
O86.4 Pyrexia of unknown origin following delivery	0.016	0.984	0.000
O87 Venous complications in the puerperium	0.016	0.984	0.000
O82.0 Delivery by elective Caesarean section	0.016	0.984	0.000
I65.1 Occlusion and stenosis of basilar artery	0.000	0.984	0.016
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.016	0.984	0.000
I28 Other diseases of pulmonary vessels	0.000	0.984	0.016
O67.8 Other intrapartum haemorrhage	0.016	0.984	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.016	0.984	0.000
O91 Infections of breast associated with childbirth	0.016	0.984	0.000
O88 Obstetric embolism	0.016	0.984	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.016	0.984	0.000
O60.3 Preterm delivery without spontaneous labour	0.015	0.984	0.000
O60.2 Preterm spontaneous labour with term delivery	0.015	0.984	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.015	0.984	0.000
O60.0 Preterm labour without delivery	0.015	0.984	0.000
M35.3 Polymyalgia rheumatica	0.000	0.984	0.016
O21.9 Vomiting of pregnancy, unspecified	0.015	0.984	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.984	0.015
O21.8 Other vomiting complicating pregnancy	0.015	0.984	0.000
O89 Complications of anaesthesia during the puerperium	0.015	0.984	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.015	0.985	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.015	0.985	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.015	0.985	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.015	0.985	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.015	0.985	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.015	0.985	0.000
O65.0 Obstructed labour due to deformed pelvis	0.015	0.985	0.000
O21.2 Late vomiting of pregnancy	0.015	0.985	0.000
O04 Medical abortion	0.015	0.985	0.000
I81 Portal vein thrombosis	0.000	0.985	0.015
O80 Single spontaneous delivery	0.015	0.985	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.015	0.985	0.000
O71.8 Other specified obstetric trauma	0.015	0.985	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.015	0.985	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.015	0.985	0.000
O82.8 Other single delivery by Caesarean section	0.015	0.985	0.000
O82.2 Delivery by Caesarean hysterectomy	0.015	0.985	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.015	0.985	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.015	0.985	0.000
O29.6 Failed or difficult intubation during pregnancy	0.015	0.985	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.015	0.985	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.015	0.985	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.015	0.985	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.015	0.985	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.015	0.985	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.015	0.985	0.000
O01.9 Hydatidiform mole, unspecified	0.015	0.985	0.000
O01.1 Incomplete and partial hydatidiform mole	0.015	0.985	0.000
O01.0 Classical hydatidiform mole	0.015	0.985	0.000
O05.9 Complete or unspecified, without complication	0.015	0.985	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.015	0.985	0.000
O05.7 Complete or unspecified, complicated by embolism	0.015	0.985	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.015	0.985	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.015	0.985	0.000
O05.4 Incomplete, without complication	0.015	0.985	0.000
O05.3 Incomplete, with other and unspecified complications	0.015	0.985	0.000
O05.2 Incomplete, complicated by embolism	0.015	0.985	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.015	0.985	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.015	0.985	0.000
O06.9 Complete or unspecified, without complication	0.015	0.985	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.015	0.985	0.000
O06.7 Complete or unspecified, complicated by embolism	0.015	0.985	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.015	0.985	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.015	0.985	0.000
O06.4 Incomplete, without complication	0.015	0.985	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations