TreeWAS – Variant ID: rs7112365

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K08.3 Retained dental root	0.202	0.798	0.000
K08 Other disorders of teeth and supporting structures	0.184	0.816	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.175	0.825	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.166	0.834	0.000
F31 Bipolar affective disorder	0.135	0.865	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.132	0.868	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.129	0.871	0.000
F31.9 Bipolar affective disorder, unspecified	0.125	0.875	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.123	0.877	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.119	0.880	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.118	0.882	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.116	0.884	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.115	0.884	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.111	0.889	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.109	0.891	0.000
K05 Gingivitis and periodontal diseases	0.104	0.896	0.000
K05.6 Periodontal disease, unspecified	0.101	0.899	0.000
K10 Other diseases of jaws	0.099	0.901	0.000
H53.2 Diplopia	0.099	0.901	0.000
K12 Stomatitis and related lesions	0.098	0.902	0.000
F31.8 Other bipolar affective disorders	0.097	0.903	0.000
K07 Dentofacial anomalies [including malocclusion]	0.097	0.903	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.097	0.903	0.000
K12.1 Other forms of stomatitis	0.096	0.904	0.000
F31.7 Bipolar affective disorder, currently in remission	0.094	0.906	0.000
K00 Disorders of tooth development and eruption	0.089	0.911	0.000
K07.3 Anomalies of tooth position	0.089	0.911	0.000
K10.2 Inflammatory conditions of jaws	0.087	0.913	0.000
K02 Dental caries	0.085	0.915	0.000
K03 Other diseases of hard tissues of teeth	0.084	0.916	0.000
K05.1 Chronic gingivitis	0.083	0.917	0.000
K10.9 Disease of jaws, unspecified	0.079	0.921	0.000
K07.6 Temporomandibular joint disorders	0.078	0.922	0.000
K12.3 Oral mucositis (ulcerative)	0.078	0.922	0.000
K09 Cysts of oral region, not elsewhere classified	0.077	0.923	0.000
K10.0 Developmental disorders of jaws	0.075	0.925	0.000
K05.2 Acute periodontitis	0.074	0.925	0.000
K05.5 Other periodontal diseases	0.074	0.925	0.000
K05.4 Periodontosis	0.074	0.925	0.000
K05.0 Acute gingivitis	0.074	0.925	0.000
K10.8 Other specified diseases of jaws	0.073	0.926	0.000
K00.6 Disturbances in tooth eruption	0.073	0.927	0.000
K10.3 Alveolitis of jaws	0.071	0.929	0.000
K10.1 Giant cell granuloma, central	0.071	0.929	0.000
K02.1 Caries of dentin	0.071	0.929	0.000
K00.1 Supernumerary teeth	0.071	0.929	0.000
K02.9 Dental caries, unspecified	0.071	0.929	0.000
K07.8 Other dentofacial anomalies	0.069	0.930	0.000
K07.5 Dentofacial functional abnormalities	0.069	0.930	0.000
K07.0 Major anomalies of jaw size	0.069	0.930	0.000
K07.9 Dentofacial anomaly, unspecified	0.069	0.931	0.000
K07.4 Malocclusion, unspecified	0.067	0.933	0.000
K07.2 Anomalies of dental arch relationship	0.067	0.933	0.000
K03.3 Pathological resorption of teeth	0.066	0.934	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.065	0.935	0.000
K00.8 Other disorders of tooth development	0.064	0.936	0.000
K00.7 Teething syndrome	0.064	0.936	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.064	0.936	0.000
K00.4 Disturbances in tooth formation	0.064	0.936	0.000
K00.3 Mottled teeth	0.064	0.936	0.000
K00.2 Abnormalities of size and form of teeth	0.064	0.936	0.000
K00.0 Anodontia	0.064	0.936	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.064	0.936	0.000
K02.5 Caries with pulp exposure	0.061	0.939	0.000
K02.4 Odontoclasia	0.061	0.939	0.000
K02.3 Arrested dental caries	0.061	0.939	0.000
K02.2 Caries of cementum	0.061	0.939	0.000
K02.0 Caries limited to enamel	0.061	0.939	0.000
K09.0 Developmental odontogenic cysts	0.061	0.939	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.061	0.939	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.061	0.939	0.000
K00.9 Disorder of tooth development, unspecified	0.061	0.939	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.060	0.939	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.060	0.939	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.060	0.939	0.000
K03.6 Deposits [accretions] on teeth	0.060	0.939	0.000
K03.5 Ankylosis of teeth	0.060	0.939	0.000
K03.4 Hypercementosis	0.060	0.939	0.000
K03.2 Erosion of teeth	0.060	0.939	0.000
K03.1 Abrasion of teeth	0.060	0.939	0.000
K03.0 Excessive attrition of teeth	0.060	0.939	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.060	0.940	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.058	0.942	0.000
K09.9 Cyst of oral region, unspecified	0.055	0.944	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.055	0.945	0.000
K09.2 Other cysts of jaw	0.054	0.946	0.000
K05.22 Aggressive periodontitis, generalized	0.053	0.946	0.000
K05.3 Chronic periodontitis	0.053	0.947	0.000
K12.2 Cellulitis and abscess of mouth	0.053	0.947	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.051	0.949	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.051	0.949	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.050	0.950	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.048	0.951	0.000
K06.1 Gingival enlargement	0.047	0.953	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.047	0.953	0.000
K01 Embedded and impacted teeth	0.047	0.953	0.000
K12.0 Recurrent oral aphthae	0.046	0.954	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.046	0.954	0.000
K06.0 Gingival recession	0.046	0.954	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.045	0.955	0.000
K14 Diseases of tongue	0.044	0.956	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.041	0.959	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.041	0.959	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.040	0.960	0.000
K02.8 Other dental caries	0.038	0.962	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.037	0.963	0.000
K04 Diseases of pulp and periapical tissues	0.035	0.965	0.000
K14.6 Glossodynia	0.034	0.966	0.000
K14.5 Plicated tongue	0.031	0.968	0.000
K14.4 Atrophy of tongue papillae	0.031	0.968	0.000
K14.3 Hypertrophy of tongue papillae	0.031	0.968	0.000
K14.2 Median rhomboid glossitis	0.031	0.968	0.000
K14.1 Geographic tongue	0.031	0.968	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.031	0.969	0.000
K11 Diseases of salivary glands	0.030	0.970	0.000
K14.9 Disease of tongue, unspecified	0.029	0.971	0.000
K01.0 Embedded teeth	0.028	0.972	0.000
K04.5 Chronic apical periodontitis	0.027	0.973	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.027	0.973	0.000
K14.0 Glossitis	0.027	0.973	0.000
F30-F39 Mood [affective] disorders	0.026	0.974	0.000
K04.3 Abnormal hard tissue formation in pulp	0.025	0.974	0.000
K04.2 Pulp degeneration	0.025	0.974	0.000
K04.1 Necrosis of pulp	0.025	0.974	0.000
K04.0 Pulpitis	0.024	0.976	0.000
K11.3 Abscess of salivary gland	0.024	0.976	0.000
K04.6 Periapical abscess with sinus	0.024	0.976	0.000
K11.1 Hypertrophy of salivary gland	0.024	0.976	0.000
K04.7 Periapical abscess without sinus	0.022	0.978	0.000
H43.8 Other disorders of vitreous body	0.000	0.978	0.022
K11.4 Fistula of salivary gland	0.021	0.978	0.000
K11.0 Atrophy of salivary gland	0.021	0.978	0.000
F33 Recurrent depressive disorder	0.021	0.979	0.000
K11.7 Disturbances of salivary secretion	0.020	0.980	0.000
K13 Other diseases of lip and oral mucosa	0.020	0.980	0.000
F38 Other mood [affective] disorders	0.019	0.981	0.000
F39 Unspecified mood [affective] disorder	0.019	0.981	0.000
H43 Disorders of vitreous body	0.000	0.981	0.019
K11.2 Sialoadenitis	0.019	0.981	0.000
K11.9 Disease of salivary gland, unspecified	0.018	0.981	0.000
H43.3 Other vitreous opacities	0.000	0.981	0.019
F30 Manic episode	0.018	0.982	0.000
F34 Persistent mood [affective] disorders	0.018	0.982	0.000
H53 Visual disturbances	0.018	0.982	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.018	0.982	0.000
K11.6 Mucocele of salivary gland	0.017	0.983	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.017	0.983	0.000
F33.9 Recurrent depressive disorder, unspecified	0.017	0.983	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.017	0.983	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.016	0.984	0.000
H53.8 Other visual disturbances	0.016	0.984	0.000
H43.1 Vitreous haemorrhage	0.000	0.985	0.015
F33.8 Other recurrent depressive disorders	0.015	0.985	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.015	0.985	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.015	0.985	0.000
K01.1 Impacted teeth	0.015	0.985	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.014	0.986	0.000
K13.5 Oral submucous fibrosis	0.014	0.986	0.000
K13.3 Hairy leukoplakia	0.014	0.986	0.000
K13.1 Cheek and lip biting	0.014	0.986	0.000
C01 Malignant neoplasm of base of tongue	0.014	0.986	0.000
F38.8 Other specified mood [affective] disorders	0.014	0.986	0.000
F38.1 Other recurrent mood [affective] disorders	0.014	0.986	0.000
F38.0 Other single mood [affective] disorders	0.014	0.986	0.000
H53.4 Visual field defects	0.014	0.986	0.000
H43.0 Vitreous prolapse	0.000	0.986	0.014
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.014	0.986	0.000
F30.0 Hypomania	0.014	0.986	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.013	0.986	0.000
F30.8 Other manic episodes	0.013	0.987	0.000
F30.2 Mania with psychotic symptoms	0.013	0.987	0.000
F30.1 Mania without psychotic symptoms	0.013	0.987	0.000
K11.5 Sialolithiasis	0.013	0.987	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.013	0.987	0.000
F34.8 Other persistent mood [affective] disorders	0.013	0.987	0.000
F34.0 Cyclothymia	0.013	0.987	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.987	0.013
H53.6 Night blindness	0.013	0.987	0.000
H53.5 Colour vision deficiencies	0.013	0.987	0.000
H53.3 Other disorders of binocular vision	0.013	0.987	0.000
H43.2 Crystalline deposits in vitreous body	0.000	0.987	0.013
C07 Malignant neoplasm of parotid gland	0.012	0.988	0.000
F30.9 Manic episode, unspecified	0.012	0.988	0.000
F34.1 Dysthymia	0.012	0.988	0.000
K11.8 Other diseases of salivary glands	0.011	0.988	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.012	0.988	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.011	0.988	0.000
C09 Malignant neoplasm of tonsil	0.011	0.989	0.000
C13 Malignant neoplasm of hypopharynx	0.011	0.989	0.000
M06.9 Rheumatoid arthritis, unspecified	0.011	0.989	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.011	0.989	0.000
C10 Malignant neoplasm of oropharynx	0.011	0.989	0.000
C11 Malignant neoplasm of nasopharynx	0.011	0.989	0.000
R94 Abnormal results of function studies	0.011	0.989	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.010	0.989	0.000
C04 Malignant neoplasm of floor of mouth	0.010	0.989	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.011	0.989	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.010	0.990	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.010	0.990	0.000
C05 Malignant neoplasm of palate	0.010	0.990	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.010	0.990	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.010	0.990	0.000
C03 Malignant neoplasm of gum	0.010	0.990	0.000
C00 Malignant neoplasm of lip	0.010	0.990	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.010	0.990	0.000
R94.5 Abnormal results of liver function studies	0.010	0.990	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.010	0.990	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.010	0.990	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.010	0.990	0.000
K14.8 Other diseases of tongue	0.010	0.990	0.000
C09.9 Tonsil, unspecified	0.010	0.990	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.010	0.990	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
K04.8 Radicular cyst	0.010	0.990	0.000
C02.9 Tongue, unspecified	0.010	0.990	0.000
C13.9 Hypopharynx, unspecified	0.010	0.990	0.000
C12 Malignant neoplasm of pyriform sinus	0.010	0.990	0.000
R94.6 Abnormal results of thyroid function studies	0.009	0.991	0.000
R94.4 Abnormal results of kidney function studies	0.009	0.991	0.000
C14.0 Pharynx, unspecified	0.009	0.991	0.000
C10.9 Oropharynx, unspecified	0.009	0.991	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.009	0.991	0.000
C11.9 Nasopharynx, unspecified	0.009	0.991	0.000
C02.1 Border of tongue	0.009	0.991	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.009	0.991	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.009	0.991	0.000
C02.8 Overlapping lesion of tongue	0.008	0.991	0.000
C02.4 Lingual tonsil	0.008	0.991	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.008	0.991	0.000
C02.2 Ventral surface of tongue	0.008	0.991	0.000
C02.0 Dorsal surface of tongue	0.008	0.991	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.009	0.991	0.000
C09.8 Overlapping lesion of tonsil	0.008	0.992	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.008	0.992	0.000
C09.0 Tonsillar fossa	0.008	0.992	0.000
C13.8 Overlapping lesion of hypopharynx	0.008	0.992	0.000
C13.2 Posterior wall of hypopharynx	0.008	0.992	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.008	0.992	0.000
C13.0 Postcricoid region	0.008	0.992	0.000
R94.2 Abnormal results of pulmonary function studies	0.008	0.992	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.008	0.992	0.000
C04.9 Floor of mouth, unspecified	0.008	0.992	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.992	0.008
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.008	0.992	0.000
C14.2 Waldeyer's ring	0.008	0.992	0.000
C10.8 Overlapping lesion of oropharynx	0.008	0.992	0.000
C10.4 Branchial cleft	0.008	0.992	0.000
C10.3 Posterior wall of oropharynx	0.008	0.992	0.000
C10.2 Lateral wall of oropharynx	0.008	0.992	0.000
C10.1 Anterior surface of epiglottis	0.008	0.992	0.000
C10.0 Vallecula	0.008	0.992	0.000
C11.8 Overlapping lesion of nasopharynx	0.008	0.992	0.000
C11.3 Anterior wall of nasopharynx	0.008	0.992	0.000
C11.2 Lateral wall of nasopharynx	0.008	0.992	0.000
C11.1 Posterior wall of nasopharynx	0.008	0.992	0.000
C11.0 Superior wall of nasopharynx	0.008	0.992	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.008	0.992	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.008	0.992	0.000
R94.0 Abnormal results of function studies of central nervous system	0.008	0.992	0.000
C71 Malignant neoplasm of brain	0.008	0.992	0.000
R94.7 Abnormal results of other endocrine function studies	0.008	0.992	0.000
C04.8 Overlapping lesion of floor of mouth	0.008	0.992	0.000
C04.1 Lateral floor of mouth	0.008	0.992	0.000
C04.0 Anterior floor of mouth	0.008	0.992	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.008	0.992	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.008	0.992	0.000
R94.3 Abnormal results of cardiovascular function studies	0.008	0.992	0.000
H53-H54 Visual disturbances and blindness	0.008	0.992	0.000
C05.1 Soft palate	0.007	0.992	0.000
C05.9 Palate, unspecified	0.007	0.992	0.000
C05.8 Overlapping lesion of palate	0.007	0.992	0.000
C05.2 Uvula	0.007	0.992	0.000
C05.0 Hard palate	0.007	0.992	0.000
M06 Other rheumatoid arthritis	0.008	0.992	0.000
C00.9 Lip, unspecified	0.007	0.992	0.000
C00.8 Overlapping lesion of lip	0.007	0.992	0.000
C00.6 Commissure of lip	0.007	0.992	0.000
C00.5 Lip, unspecified, inner aspect	0.007	0.992	0.000
C00.4 Lower lip, inner aspect	0.007	0.992	0.000
C00.3 Upper lip, inner aspect	0.007	0.992	0.000
C00.2 External lip, unspecified	0.007	0.992	0.000
C00.1 External lower lip	0.007	0.992	0.000
C00.0 External upper lip	0.007	0.992	0.000
C03.9 Gum, unspecified	0.007	0.992	0.000
C03.1 Lower gum	0.007	0.992	0.000
C03.0 Upper gum	0.007	0.992	0.000
C06.9 Mouth, unspecified	0.007	0.992	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.007	0.992	0.000
C06.2 Retromolar area	0.007	0.992	0.000
C06.1 Vestibule of mouth	0.007	0.992	0.000
C06.0 Cheek mucosa	0.007	0.992	0.000
C08.9 Major salivary gland, unspecified	0.007	0.992	0.000
C08.8 Overlapping lesion of major salivary glands	0.007	0.992	0.000
C08.1 Sublingual gland	0.007	0.992	0.000
C08.0 Submandibular gland	0.007	0.992	0.000
C71.2 Temporal lobe	0.007	0.993	0.000
C71.1 Frontal lobe	0.007	0.993	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.007	0.993	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.007	0.993	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.007	0.993	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M06.3 Rheumatoid nodule	0.007	0.993	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.994	0.006
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.006	0.994	0.000
H53.9 Visual disturbance, unspecified	0.006	0.994	0.000
K13.0 Diseases of lips	0.006	0.994	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.006	0.994	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.006	0.994	0.000
C71.7 Brain stem	0.006	0.994	0.000
C71.6 Cerebellum	0.006	0.994	0.000
C71.5 Cerebral ventricle	0.006	0.994	0.000
C71.4 Occipital lobe	0.006	0.994	0.000
M06.0 Seronegative rheumatoid arthritis	0.006	0.994	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.006	0.994	0.000
M06.4 Inflammatory polyarthropathy	0.006	0.994	0.000
M06.34 Rheumatoid nodule (Hand)	0.006	0.994	0.000
M06.8 Other specified rheumatoid arthritis	0.006	0.994	0.000
M06.2 Rheumatoid bursitis	0.006	0.994	0.000
M06.1 Adult-onset Still's disease	0.006	0.994	0.000
H54 Blindness and low vision	0.006	0.994	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.005	0.995	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.005	0.995	0.000
K56.2 Volvulus	0.005	0.995	0.000
C71.8 Overlapping lesion of brain	0.005	0.995	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.005	0.995	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.005	0.995	0.000
M21.3 Wrist or foot drop (acquired)	0.005	0.995	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.005	0.995	0.000
M06.38 Rheumatoid nodule (Other)	0.005	0.995	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.005	0.995	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.005	0.995	0.000
M06.33 Rheumatoid nodule (Forearm)	0.005	0.995	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.005	0.995	0.000
H53.0 Amblyopia ex anopsia	0.005	0.995	0.000
R90.0 Intracranial space-occupying lesion	0.005	0.995	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.995	0.005
H54.5 Low vision, one eye	0.005	0.995	0.000
J98.4 Other disorders of lung	0.005	0.995	0.000
M21.0 Valgus deformity, not elsewhere classified	0.005	0.995	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.005	0.995	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.005	0.995	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.004	0.995	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.004	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.995	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.004	0.995	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.004	0.995	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.004	0.995	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.004	0.995	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.004	0.995	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
H54.1 Blindness, one eye, low vision, other eye	0.004	0.995	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.004	0.996	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.004	0.996	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.004	0.996	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.004	0.996	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.004	0.996	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.004	0.996	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.004	0.996	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.004	0.996	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.004	0.996	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.004	0.996	0.000
H54.6 Unqualified visual loss, one eye	0.004	0.996	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
M21 Other acquired deformities of limbs	0.004	0.996	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.004	0.996	0.000
M06.18 Adult-onset Still's disease (Other)	0.004	0.996	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.004	0.996	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.004	0.996	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.004	0.996	0.000
M06.14 Adult-onset Still's disease (Hand)	0.004	0.996	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.004	0.996	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.004	0.996	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.004	0.996	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.004	0.996	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.004	0.996	0.000
M06.28 Rheumatoid bursitis (Other)	0.004	0.996	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.004	0.996	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.004	0.996	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.004	0.996	0.000
M06.24 Rheumatoid bursitis (Hand)	0.004	0.996	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.004	0.996	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.004	0.996	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.004	0.996	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.004	0.996	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.004	0.996	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.004	0.996	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.004	0.996	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.004	0.996	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.004	0.996	0.000
H54.3 Unqualified visual loss, both eyes	0.004	0.996	0.000
H54.2 Low vision, both eyes	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
C69 Malignant neoplasm of eye and adnexa	0.004	0.996	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.996	0.004
Z82.3 Family history of stroke	0.004	0.996	0.000
J69.0 Pneumonitis due to food and vomit	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
H54.7 Unspecified visual loss	0.004	0.996	0.000
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.004	0.996	0.000
C69.9 Eye, unspecified	0.004	0.996	0.000
M48.06 Spinal stenosis (Lumbar region)	0.004	0.996	0.000
D12.5 Sigmoid colon	0.000	0.996	0.004
H44 Disorders of globe	0.000	0.996	0.004
F32 Depressive episode	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.000	0.996	0.004
M21.39 Wrist or foot drop (acquired)-Site unspec	0.004	0.996	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.004	0.996	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.004	0.996	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.004	0.996	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.004	0.996	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.004	0.996	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.004	0.996	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.004	0.996	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.004	0.996	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.996	0.004
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.996	0.004
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.996	0.004
J98.8 Other specified respiratory disorders	0.004	0.996	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.996	0.000
J98 Other respiratory disorders	0.004	0.996	0.000
Y40.0 Penicillins	0.004	0.996	0.000
Z83.3 Family history of diabetes mellitus	0.004	0.996	0.000
M21.7 Unequal limb length (acquired)	0.004	0.996	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
M48.0 Spinal stenosis	0.004	0.996	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.004	0.996	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.996	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.996	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.996	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.996	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.996	0.000
C70 Malignant neoplasm of meninges	0.003	0.996	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.004	0.996	0.000
I21 Acute myocardial infarction	0.000	0.996	0.004
M21.2 Flexion deformity	0.003	0.996	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.003	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.003	0.997	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.003	0.997	0.000
C69.6 Orbit	0.003	0.997	0.000
C69.5 Lachrymal gland and duct	0.003	0.997	0.000
C69.4 Ciliary body	0.003	0.997	0.000
C69.2 Retina	0.003	0.997	0.000
C69.1 Cornea	0.003	0.997	0.000
C69.0 Conjunctiva	0.003	0.997	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.003	0.997	0.000
C69.3 Choroid	0.003	0.997	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.997	0.003
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
F32.0 Mild depressive episode	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
J98.9 Respiratory disorder, unspecified	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
H44.9 Disorder of globe, unspecified	0.000	0.997	0.003
H44.8 Other disorders of globe	0.000	0.997	0.003
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.997	0.003
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.997	0.003
H44.5 Degenerated conditions of globe	0.000	0.997	0.003
H44.4 Hypotony of eye	0.000	0.997	0.003
H44.3 Other degenerative disorders of globe	0.000	0.997	0.003
H44.1 Other endophthalmitis	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
F32.8 Other depressive episodes	0.003	0.997	0.000
I12 Hypertensive renal disease	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.997	0.003
G55.2 Nerve root and plexus compressions in spondylosis	0.003	0.997	0.000
J98.2 Interstitial emphysema	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations