TreeWAS – Variant ID: rs7158872

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K81.1 Chronic cholecystitis	0.044	0.956	0.000
K81 Cholecystitis	0.038	0.962	0.000
K81.0 Acute cholecystitis	0.035	0.965	0.000
K81.8 Other cholecystitis	0.033	0.967	0.000
K81.9 Cholecystitis, unspecified	0.030	0.970	0.000
B18.2 Chronic viral hepatitis C	0.000	0.976	0.024
D03 Melanoma in situ	0.000	0.983	0.017
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.984	0.016
D03.5 Melanoma in situ of trunk	0.000	0.984	0.016
D03.4 Melanoma in situ of scalp and neck	0.000	0.985	0.015
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.985	0.015
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.986	0.014
D03.0 Melanoma in situ of lip	0.000	0.987	0.013
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.988	0.012
D03.9 Melanoma in situ, unspecified	0.000	0.988	0.012
D03.8 Melanoma in situ of other sites	0.000	0.988	0.012
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.989	0.011
B18 Chronic viral hepatitis	0.000	0.989	0.011
R70.0 Elevated erythrocyte sedimentation rate	0.010	0.990	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.990	0.010
S12.20 Fracture of other specified cervical vertebra (closed)	0.010	0.990	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.009	0.991	0.000
R71 Abnormality of red blood cells	0.009	0.991	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.009	0.991	0.000
D73.0 Hyposplenism	0.009	0.991	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R77 Other abnormalities of plasma proteins	0.008	0.992	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R77.8 Other specified abnormalities of plasma proteins	0.008	0.992	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.008	0.992	0.000
B18.8 Other chronic viral hepatitis	0.000	0.992	0.008
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.992	0.008
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.008	0.992	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R70.1 Abnormal plasma viscosity	0.007	0.992	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.993	0.007
R79 Other abnormal findings of blood chemistry	0.007	0.993	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.993	0.007
R77.0 Abnormality of albumin	0.007	0.993	0.000
N04.9 Unspecified	0.007	0.993	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.993	0.007
R74 Abnormal serum enzyme levels	0.007	0.993	0.000
I42.9 Cardiomyopathy, unspecified	0.007	0.993	0.000
R77.1 Abnormality of globulin	0.006	0.993	0.000
D73 Diseases of spleen	0.006	0.994	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.006	0.994	0.000
S12.2 Fracture of other specified cervical vertebra	0.006	0.994	0.000
R77.2 Abnormality of alphafetoprotein	0.006	0.994	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.006	0.994	0.000
R77.9 Abnormality of plasma protein, unspecified	0.006	0.994	0.000
D73.4 Cyst of spleen	0.006	0.994	0.000
R74.8 Abnormal levels of other serum enzymes	0.006	0.994	0.000
D73.8 Other diseases of spleen	0.006	0.994	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.994	0.006
R79.0 Abnormal level of blood mineral	0.006	0.994	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.005	0.995	0.000
T93 Sequelae of injuries of lower limb	0.005	0.995	0.000
N04 Nephrotic syndrome	0.005	0.995	0.000
D73.3 Abscess of spleen	0.005	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.005	0.995	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.005	0.995	0.000
S29.9 Unspecified injury of thorax	0.000	0.995	0.005
R78 Findings of drugs and other substances, not normally found in blood	0.005	0.995	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.005	0.995	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.005	0.995	0.000
D73.9 Disease of spleen, unspecified	0.005	0.995	0.000
D73.2 Chronic congestive splenomegaly	0.005	0.995	0.000
N04.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.005	0.995	0.000
T93.0 Sequelae of open wound of lower limb	0.005	0.995	0.000
D73.1 Hypersplenism	0.005	0.995	0.000
N04.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
N04.8 Other	0.004	0.995	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.005	0.995	0.000
N04.0 Minor glomerular abnormality	0.004	0.995	0.000
B15-B19 Viral hepatitis	0.000	0.996	0.004
T93.9 Sequelae of unspecified injury of lower limb	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
R76 Other abnormal immunological findings in serum	0.004	0.996	0.000
D05.1 Intraductal carcinoma in situ	0.004	0.996	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.004	0.996	0.000
N04.6 Dense deposit disease	0.004	0.996	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.996	0.000
O61.0 Failed medical induction of labour	0.000	0.996	0.004
O97 Death from sequelae of direct obstetric causes	0.004	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.996	0.000
O95 Obstetric death of unspecified cause	0.004	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.004	0.996	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.004	0.996	0.000
R78.6 Finding of steroid agent in blood	0.004	0.996	0.000
R78.5 Finding of psychotropic drug in blood	0.004	0.996	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.004	0.996	0.000
R78.3 Finding of hallucinogen in blood	0.004	0.996	0.000
R78.2 Finding of cocaine in blood	0.004	0.996	0.000
R78.1 Finding of opiate drug in blood	0.004	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.004	0.996	0.000
S12 Fracture of neck	0.004	0.996	0.000
N76.4 Abscess of vulva	0.004	0.996	0.000
T93.1 Sequelae of fracture of femur	0.004	0.996	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.004	0.996	0.000
B16 Acute hepatitis B	0.000	0.996	0.004
T92.9 Sequelae of unspecified injury of upper limb	0.004	0.996	0.000
C69.3 Choroid	0.004	0.996	0.000
O20.0 Threatened abortion	0.000	0.996	0.004
T92.1 Sequelae of fracture of arm	0.004	0.996	0.000
T92.0 Sequelae of open wound of upper limb	0.004	0.996	0.000
B19 Unspecified viral hepatitis	0.000	0.996	0.004
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.003	0.996	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.003	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.004	0.996	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.004	0.996	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.996	0.000
S12.7 Multiple fractures of cervical spine	0.003	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.997	0.003
D73.5 Infarction of spleen	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.997	0.003
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.003	0.997	0.000
R76.2 False-positive serological test for syphilis	0.003	0.997	0.000
R76.1 Abnormal reaction to tuberculin test	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.997	0.003
S12.9 Fracture of neck, part unspecified	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.003	0.997	0.000
O96.9 Death from unspecified obstetric cause	0.003	0.997	0.000
O96.1 Death from indirect obstetric cause	0.003	0.997	0.000
O96.0 Death from direct obstetric cause	0.003	0.997	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.003	0.997	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.003	0.997	0.000
O97.0 Death from sequelae of direct obstetric cause	0.003	0.997	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
B15 Acute hepatitis A	0.000	0.997	0.003
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
Z34 Supervision of normal pregnancy	0.000	0.997	0.003
R78.0 Finding of alcohol in blood	0.003	0.997	0.000
O86.4 Pyrexia of unknown origin following delivery	0.000	0.997	0.003
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.003	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
S12.8 Fracture of other parts of neck	0.003	0.997	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
B19.9 Unspecified viral hepatitis without coma	0.000	0.997	0.003
I89.1 Lymphangitis	0.003	0.997	0.000
B17 Other acute viral hepatitis	0.000	0.997	0.003
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.997	0.003
S12.0 Fracture of first cervical vertebra	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.997	0.003
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.997	0.003
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.997	0.003
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.997	0.003
C71.1 Frontal lobe	0.003	0.997	0.000
R76.0 Raised antibody titer	0.003	0.997	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.003	0.997	0.000
C69.2 Retina	0.003	0.997	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.003	0.997	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.997	0.003
K00.6 Disturbances in tooth eruption	0.000	0.997	0.003
Z34.0 Supervision of normal first pregnancy	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.003	0.997	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.003	0.997	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.003	0.997	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.003	0.997	0.000
R73 Elevated blood glucose level	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
S12.71 Multiple fractures of cervical spine (open)	0.003	0.997	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.003	0.997	0.000
C69.0 Conjunctiva	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.997	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.000	0.997	0.003
J20 Acute bronchitis	0.000	0.997	0.003
J86.9 Pyothorax without fistula	0.003	0.997	0.000
B44.9 Aspergillosis, unspecified	0.000	0.997	0.003
T94.1 Sequelae of injuries, not specified by body region	0.003	0.997	0.000
D70 Agranulocytosis	0.003	0.997	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.997	0.000
C69.9 Eye, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.997	0.000
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.997	0.000
B44 Aspergillosis	0.000	0.997	0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.997	0.003
T98 Sequelae of other and unspecified effects of external causes	0.002	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.997	0.000
C69.5 Lachrymal gland and duct	0.002	0.997	0.000
C69.1 Cornea	0.002	0.997	0.000
C71.6 Cerebellum	0.002	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.997	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
B15.0 Hepatitis A with hepatic coma	0.000	0.997	0.002
B17.9 Acute viral hepatitis, unspecified	0.000	0.997	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.002	0.997	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
I98.0 Cardiovascular syphilis	0.002	0.997	0.000
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
D21.9 Connective and other soft tissue, unspecified	0.000	0.997	0.002
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.997	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.997	0.000
S12.81 Fracture of other parts of neck (open)	0.002	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.002
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
S12.01 Fracture of first cervical vertebra (open)	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
B17.2 Acute hepatitis E	0.000	0.998	0.002
D21.5 Connective and other soft tissue of pelvis	0.000	0.998	0.002
D21.4 Connective and other soft tissue of abdomen	0.000	0.998	0.002
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
B17.8 Other specified acute viral hepatitis	0.000	0.998	0.002
G93.0 Cerebral cysts	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
J20.7 Acute bronchitis due to echovirus	0.000	0.998	0.002
J20.6 Acute bronchitis due to rhinovirus	0.000	0.998	0.002
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.998	0.002
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.998	0.002
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.998	0.002
J20.2 Acute bronchitis due to streptococcus	0.000	0.998	0.002
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.998	0.002
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.998	0.002
K56.1 Intussusception	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
J20.8 Acute bronchitis due to other specified organisms	0.000	0.998	0.002
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.000	0.998	0.002
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
B44.8 Other forms of aspergillosis	0.000	0.998	0.002
T79.5 Traumatic anuria	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
S12.11 Fracture of second cervical vertebra (open)	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.998	0.001
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.000	0.998	0.002
C67.6 Ureteric orifice	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.998	0.002
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.998	0.002
M67.4 Ganglion	0.000	0.998	0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.998	0.002
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.998	0.002
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.000	0.998	0.002
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
W19.4 Street and highway	0.000	0.998	0.002
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
D21.3 Connective and other soft tissue of thorax	0.000	0.998	0.002
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
F80.1 Expressive language disorder	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.000	0.998	0.002
O00.1 Tubal pregnancy	0.000	0.998	0.002
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.998	0.002
S10-S19 Injuries to the neck	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
A41.9 Septicaemia, unspecified	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M67.49 Ganglion, multiple sites	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.000	0.998	0.002
M67.45 Ganglion, hip	0.000	0.998	0.002
B37.4 Candidiasis of other urogenital sites	0.000	0.998	0.002
E10.9 Without complications	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
S63.1 Dislocation finger	0.000	0.998	0.002
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.002
S63.2 Multiple dislocations of fingers	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.998	0.002
C72.9 Central nervous system, unspecified	0.001	0.998	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.998	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.998	0.000
C72.4 Acoustic nerve	0.001	0.998	0.000
C72.3 Optic nerve	0.001	0.998	0.000
C72.2 Olfactory nerve	0.001	0.998	0.000
C72.1 Cauda equina	0.001	0.998	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.998	0.002
S10.7 Multiple superficial injuries of neck	0.001	0.998	0.000
S10.0 Contusion of throat	0.001	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
D72.9 Disorder of white blood cells, unspecified	0.001	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.000	0.998	0.001
C70.9 Meninges, unspecified	0.001	0.998	0.000
C70.1 Spinal meninges	0.001	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
C72.0 Spinal cord	0.001	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.998	0.001
S63.5 Sprain and strain of wrist	0.000	0.998	0.001
I42 Cardiomyopathy	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.001	0.998	0.000
T79.1 Fat embolism (traumatic)	0.001	0.998	0.000
T79.0 Air embolism (traumatic)	0.001	0.998	0.000
F09 Unspecified organic or symptomatic mental disorder	0.001	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.001	0.998	0.000
Z29.0 Isolation	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.998	0.002
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.998	0.001
C70.0 Cerebral meninges	0.001	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
S29.0 Injury of muscle and tendon at thorax level	0.000	0.998	0.001
D76.2 Haemophagocytic syndrome, infection-associated	0.001	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.001	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.001	0.998	0.000
F05.1 Delirium superimposed on dementia	0.001	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.001	0.998	0.000
S29.8 Other specified injuries of thorax	0.000	0.998	0.001
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.998	0.000
F07.1 Postencephalitic syndrome	0.001	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.998	0.002
G90.2 Horner's syndrome	0.001	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
S17 Crushing injury of neck	0.001	0.998	0.000
S15 Injury of blood vessels at neck level	0.001	0.998	0.000
S18 Traumatic amputation at neck level	0.001	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.001	0.998	0.000
C92.7 Other myeloid leukaemia	0.001	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.001	0.998	0.000
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
T23.1 Burn of first degree of wrist and hand	0.001	0.998	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.999	0.001
C10.9 Oropharynx, unspecified	0.000	0.999	0.001
B82.0 Intestinal helminthiasis, unspecified	0.000	0.999	0.001
D32.0 Cerebral meninges	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
M67.1 Other contracture of tendon (sheath)	0.000	0.999	0.001
S14.6 Injury of other and unspecified nerves of neck	0.001	0.999	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.999	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.999	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.999	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.999	0.000
B80 Enterobiasis	0.000	0.999	0.001
J86 Pyothorax	0.001	0.999	0.000
O61 Failed induction of labour	0.000	0.999	0.001
C04.0 Anterior floor of mouth	0.000	0.999	0.001
C92.0 Acute myeloid leukaemia	0.001	0.999	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
C91.9 Lymphoid leukaemia, unspecified	0.001	0.999	0.000
E85.3 Secondary systemic amyloidosis	0.001	0.999	0.000
I42.5 Other restrictive cardiomyopathy	0.001	0.999	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.999	0.000
N13.4 Hydroureter	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
A49.9 Bacterial infection, unspecified	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.000	0.999	0.001
Z57.2 Occupational exposure to dust	0.001	0.999	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.999	0.001
W19.6 Industrial and construction area	0.000	0.999	0.001
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.999	0.001
F01 Vascular dementia	0.001	0.999	0.000
C92.5 Acute myelomonocytic leukaemia	0.001	0.999	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.001	0.999	0.000
S15.8 Injury of other blood vessels at neck level	0.001	0.999	0.000
S15.7 Injury of multiple blood vessels at neck level	0.001	0.999	0.000
S15.3 Injury of internal jugular vein	0.001	0.999	0.000
S15.2 Injury of external jugular vein	0.001	0.999	0.000
S15.1 Injury of vertebral artery	0.001	0.999	0.000
S15.0 Injury of carotid artery	0.001	0.999	0.000
S17.9 Crushing injury of neck, part unspecified	0.001	0.999	0.000
S17.8 Crushing injury of other parts of neck	0.001	0.999	0.000
S17.0 Crushing injury of larynx and traches	0.001	0.999	0.000
S63.0 Dislocation of wrist	0.000	0.999	0.001
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.999	0.001
C05.0 Hard palate	0.000	0.999	0.001
I42.4 Endocardial fibroelastosis	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
R73.9 Hyperglycaemia, unspecified	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
C92 Myeloid leukaemia	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
C05 Malignant neoplasm of palate	0.000	0.999	0.001
C92.1 Chronic myeloid leukaemia	0.001	0.999	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.001	0.999	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.999	0.001
O61.8 Other failed induction of labour	0.000	0.999	0.001
S14.3 Injury of brachial plexus	0.001	0.999	0.000
T23.3 Burn of third degree of wrist and hand	0.001	0.999	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.999	0.001
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.001	0.999	0.000
C04 Malignant neoplasm of floor of mouth	0.000	0.999	0.001
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.001	0.999	0.000
M25.36 Other instability of joint (Lower leg)	0.001	0.999	0.000
C92.2 Subacute myeloid leukaemia	0.001	0.999	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations