TreeWAS – Variant ID: rs7193230

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M21 Other acquired deformities of limbs	0.016	0.984	0.000
M21.6 Other acquired deformities of ankle and foot	0.015	0.985	0.000
M21.0 Valgus deformity, not elsewhere classified	0.015	0.985	0.000
M21.3 Wrist or foot drop (acquired)	0.015	0.985	0.000
M21.1 Varus deformity, not elsewhere classified	0.015	0.985	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.014	0.986	0.000
M21.9 Acquired deformity of limb, unspecified	0.014	0.986	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.014	0.986	0.000
M21.2 Flexion deformity	0.014	0.986	0.000
M21.7 Unequal limb length (acquired)	0.013	0.987	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.013	0.987	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.013	0.987	0.000
M21.8 Other specified acquired deformities of limbs	0.013	0.987	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.012	0.988	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.012	0.988	0.000
M21.4 Flat foot [pes planus] (acquired)	0.012	0.988	0.000
M21.24 Flexion deformity (Hand)	0.011	0.989	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.011	0.989	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.011	0.989	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.011	0.989	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.011	0.989	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.011	0.989	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.011	0.989	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.011	0.989	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.011	0.989	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.011	0.989	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.011	0.989	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.011	0.989	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.011	0.989	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.011	0.989	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.011	0.989	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.011	0.989	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.011	0.989	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
M21.20 Flexion deformity (Multiple sites)	0.011	0.989	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.011	0.989	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.011	0.989	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.011	0.989	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.011	0.989	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.011	0.989	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.011	0.989	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.011	0.989	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.011	0.989	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.011	0.989	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.011	0.989	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.011	0.989	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.011	0.989	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.011	0.989	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.011	0.989	0.000
M21.26 Flexion deformity (Lower leg)	0.011	0.989	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.011	0.989	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.010	0.990	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.010	0.990	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.010	0.990	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.010	0.990	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.010	0.990	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.010	0.990	0.000
M21.29 Flexion deformity (Site unspecified)	0.010	0.990	0.000
M21.28 Flexion deformity (Other)	0.010	0.990	0.000
M21.23 Flexion deformity (Forearm)	0.010	0.990	0.000
M21.21 Flexion deformity (Shoulder region)	0.010	0.990	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.010	0.990	0.000
M21.78 Unequal limb length (acquired)-Other	0.010	0.990	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.010	0.990	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.010	0.990	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.010	0.990	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.010	0.990	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.010	0.990	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.009	0.990	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.009	0.991	0.000
M21.22 Flexion deformity (Upper arm)	0.009	0.991	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.009	0.991	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.009	0.991	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.009	0.991	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.009	0.991	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.009	0.991	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.009	0.991	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.009	0.991	0.000
M21.27 Flexion deformity (Ankle and foot)	0.009	0.991	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.009	0.991	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.009	0.991	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.009	0.991	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.009	0.991	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.009	0.991	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.009	0.991	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.009	0.991	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.009	0.991	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.009	0.991	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.009	0.991	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.008	0.991	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.991	0.009
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.991	0.009
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.008	0.992	0.000
C16.3 Pyloric antrum	0.000	0.992	0.008
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.008	0.992	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.008	0.992	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.008	0.992	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.008	0.992	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.008	0.992	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.008	0.992	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.008	0.992	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.008	0.992	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.008	0.992	0.000
G47 Sleep disorders	0.000	0.992	0.008
K35.8 Acute appendicitis, other and unspecified	0.000	0.992	0.008
G47.4 Narcolepsy and cataplexy	0.000	0.992	0.008
G47.8 Other sleep disorders	0.000	0.993	0.007
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.000	0.993	0.007
G47.2 Disorders of the sleep-wake schedule	0.000	0.993	0.006
C16.6 Greater curvature of stomach, unspecified	0.000	0.994	0.006
C16.9 Stomach, unspecified	0.000	0.994	0.006
C16.4 Pylorus	0.000	0.994	0.006
C16.2 Body of stomach	0.000	0.994	0.006
C16.5 Lesser curvature of stomach, unspecified	0.000	0.994	0.006
G47.9 Sleep disorder, unspecified	0.000	0.994	0.006
R06.0 Dyspnoea	0.006	0.994	0.000
C16.1 Fundus of stomach	0.000	0.995	0.005
N61 Inflammatory disorders of breast	0.005	0.995	0.000
I05.1 Rheumatic mitral insufficiency	0.005	0.995	0.000
C81.9 Hodgkin's disease, unspecified	0.005	0.995	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.995	0.005
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.995	0.005
O42.9 Premature rupture of membranes, unspecified	0.000	0.995	0.005
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.995	0.005
C16.8 Overlapping lesion of stomach	0.000	0.996	0.004
O42 Premature rupture of membranes	0.000	0.996	0.004
I05.2 Mitral stenosis with insufficiency	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.996	0.004
Z94.0 Kidney transplant status	0.000	0.996	0.004
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.996	0.004
T83.0 Mechanical complication of urinary (indwelling) catheter	0.004	0.996	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
Y84.6 Urinary catheterisation	0.004	0.996	0.000
I67.9 Cerebrovascular disease, unspecified	0.004	0.996	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.996	0.004
C16.0 Cardia	0.000	0.996	0.003
C48.2 Peritoneum, unspecified	0.000	0.997	0.003
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.997	0.003
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
C81 Hodgkin's disease	0.003	0.997	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.003
Z63.5 Disruption of family by separation and divorce	0.003	0.997	0.000
Z63 Other problems related to primary support group, including family circumstances	0.003	0.997	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.997	0.003
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
I05.0 Mitral stenosis	0.003	0.997	0.000
I67.8 Other specified cerebrovascular diseases	0.003	0.997	0.000
C81.2 Mixed cellularity	0.003	0.997	0.000
C81.1 Nodular sclerosis	0.003	0.997	0.000
Z94.5 Skin transplant status	0.000	0.997	0.003
F81.9 Developmental disorder of scholastic skills, unspecified	0.003	0.997	0.000
Z94.4 Liver transplant status	0.000	0.997	0.003
Z94 Transplanted organ and tissue status	0.000	0.997	0.003
C81.0 Lymphocytic predominance	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
D21.9 Connective and other soft tissue, unspecified	0.000	0.997	0.003
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.000	0.997	0.003
I67 Other cerebrovascular diseases	0.003	0.997	0.000
C81.7 Other Hodgkin's disease	0.003	0.997	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.997	0.000
C81.3 Lymphocytic depletion	0.002	0.997	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
D21.3 Connective and other soft tissue of thorax	0.000	0.997	0.002
D21.5 Connective and other soft tissue of pelvis	0.000	0.997	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.003	0.997	0.000
Z94.2 Lung transplant status	0.000	0.997	0.002
Z63.9 Problem related to primary support group, unspecified	0.002	0.997	0.000
Z63.3 Absence of family member	0.002	0.997	0.000
Z63.2 Inadequate family support	0.002	0.997	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.003	0.997	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
C48.0 Retroperitoneum	0.000	0.998	0.002
D21.4 Connective and other soft tissue of abdomen	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Z94.3 Heart and lungs transplant status	0.000	0.998	0.002
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
Z94.6 Bone transplant status	0.000	0.998	0.002
T83.2 Mechanical complication of graft of urinary organ	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
Z94.1 Heart transplant status	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
N83.2 Other and unspecified ovarian cysts	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
W19.4 Street and highway	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
Z90.3 Acquired absence of part of stomach	0.000	0.998	0.002
S20.2 Contusion of thorax	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
K11.5 Sialolithiasis	0.000	0.998	0.002
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.002	0.998	0.000
K85 Acute pancreatitis	0.000	0.998	0.002
K85.2 Alcohol-induced acute pancreatitis	0.000	0.998	0.002
D26.0 Cervix uteri	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
H04.9 Disorder of lachrymal system, unspecified	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
D26.1 Corpus uteri	0.000	0.998	0.002
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.000	0.998	0.002
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
C48.1 Specified parts of peritoneum	0.000	0.998	0.001
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
F81 Specific developmental disorders of scholastic skills	0.001	0.998	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.998	0.001
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
T87.6 Other and unspecified complications of amputation stump	0.002	0.998	0.000
D26.9 Uterus, unspecified	0.000	0.998	0.001
D37.7 Other digestive organs	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.998	0.001
H34.1 Central retinal artery occlusion	0.001	0.998	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.998	0.002
S82.20 Fracture of shaft of tibia (closed)	0.001	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.000	0.998	0.001
R44.2 Other hallucinations	0.000	0.998	0.001
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.998	0.001
N30.8 Other cystitis	0.000	0.999	0.001
T40.4 Other synthetic narcotics	0.000	0.999	0.001
D05.1 Intraductal carcinoma in situ	0.000	0.999	0.001
H25.8 Other senile cataract	0.001	0.999	0.000
I77.6 Arteritis, unspecified	0.000	0.999	0.001
K85.3 Drug-induced acute pancreatitis	0.000	0.999	0.001
M50.0 Cervical disk disorder with myelopathy	0.001	0.999	0.000
L82 Seborrhoeic keratosis	0.000	0.999	0.001
H04.3 Acute and unspecified inflammation of lachrymal passages	0.001	0.999	0.000
H34.8 Other retinal vascular occlusions	0.001	0.999	0.000
O70.9 Perineal laceration during delivery, unspecified	0.001	0.999	0.000
F81.8 Other developmental disorders of scholastic skills	0.001	0.999	0.000
F81.3 Mixed disorder of scholastic skills	0.001	0.999	0.000
F81.2 Specific disorder of arithmetical skills	0.001	0.999	0.000
F81.1 Specific spelling disorder	0.001	0.999	0.000
F81.0 Specific reading disorder	0.001	0.999	0.000
D26 Other benign neoplasms of uterus	0.000	0.999	0.001
H04 Disorders of lachrymal system	0.001	0.999	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.999	0.001
K50.1 Crohn's disease of large intestine	0.000	0.999	0.001
M11.2 Other chondrocalcinosis	0.000	0.999	0.001
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.999	0.001
E89.5 Postprocedural testicular hypofunction	0.000	0.999	0.001
E89.4 Postprocedural ovarian failure	0.000	0.999	0.001
G91.9 Hydrocephalus, unspecified	0.001	0.999	0.000
H04.8 Other disorders of lachrymal system	0.001	0.999	0.000
H04.6 Other changes in lachrymal passages	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.999	0.001
O66.0 Obstructed labour due to shoulder dystocia	0.001	0.999	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.999	0.001
T83.1 Mechanical complication of other urinary devices and implants	0.001	0.999	0.000
D16.3 Short bones of lower limb	0.001	0.999	0.000
J38.5 Laryngeal spasm	0.000	0.999	0.001
K08.2 Atrophy of edentulous alveolar ridge	0.001	0.999	0.000
L30.9 Dermatitis, unspecified	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
S82.2 Fracture of shaft of tibia	0.001	0.999	0.000
E89.1 Postprocedural hypoinsulinaemia	0.000	0.999	0.001
G72.0 Drug-induced myopathy	0.000	0.999	0.001
J38.6 Stenosis of larynx	0.000	0.999	0.001
H04.0 Dacryoadenitis	0.001	0.999	0.000
I87.1 Compression of vein	0.001	0.999	0.000
H20.9 Iridocyclitis, unspecified	0.001	0.999	0.000
J38.3 Other diseases of vocal cords	0.000	0.999	0.001
N80.2 Endometriosis of Fallopian tube	0.000	0.999	0.001
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.999	0.001
M11.28 Other chondrocalcinosis (Other)	0.000	0.999	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.999	0.001
M11.24 Other chondrocalcinosis (Hand)	0.000	0.999	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.999	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.999	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.999	0.001
D26.7 Other parts of uterus	0.000	0.999	0.001
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.999	0.001
D29.1 Prostate	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
M75.9 Shoulder lesion, unspecified	0.000	0.999	0.001
W07.0 Home	0.000	0.999	0.001
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.999	0.001
D16.1 Short bones of upper limb	0.001	0.999	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.001	0.999	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
X45.0 Home	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
A49.9 Bacterial infection, unspecified	0.000	0.999	0.001
D37.5 Rectum	0.001	0.999	0.000
H04.4 Chronic inflammation of lachrymal passages	0.001	0.999	0.000
Z32.1 Pregnancy confirmed	0.001	0.999	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.001	0.999	0.000
M25.74 Osteophyte (Hand)	0.001	0.999	0.000
I73.0 Raynaud's syndrome	0.001	0.999	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.000	0.999	0.001
Z41.2 Routine and ritual circumcision	0.001	0.999	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.999	0.001
G11.9 Hereditary ataxia, unspecified	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
Q39.9 Congenital malformation of oesophagus, unspecified	0.000	0.999	0.001
T87.3 Neuroma of amputation stump	0.001	0.999	0.000
W49.9 Unspecified place	0.001	0.999	0.000
Z41 Procedures for purposes other than remedying health state	0.001	0.999	0.000
J38.2 Nodules of vocal cords	0.000	0.999	0.001
V48.4 Person injured while boarding or alighting	0.001	0.999	0.000
Y84.9 Medical procedure, unspecified	0.001	0.999	0.000
Y84.5 Insertion of gastric or duodenal sound	0.001	0.999	0.000
Y84.2 Radiological procedure and radiotherapy	0.001	0.999	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.999	0.001
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
Z41.3 Ear piercing	0.001	0.999	0.000
Z41.0 Hair transplant	0.001	0.999	0.000
F80.1 Expressive language disorder	0.000	0.999	0.001
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
O26.8 Other specified pregnancy-related conditions	0.001	0.999	0.000
Y84.7 Blood-sampling	0.001	0.999	0.000
Y84.3 Shock therapy	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
D16.8 Pelvic bones, sacrum and coccyx	0.001	0.999	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.999	0.001
I89.1 Lymphangitis	0.000	0.999	0.001
T40.5 Cocaine	0.000	0.999	0.001
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.000	0.999	0.001
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.999	0.001
S62.50 Fracture of thumb (closed)	0.000	0.999	0.001
D16.5 Lower jaw bone	0.001	0.999	0.000
D37.1 Stomach	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.999	0.000
N97.9 Female infertility, unspecified	0.000	0.999	0.001
M25.71 Osteophyte (Shoulder region)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
G80.1 Spastic diplegia	0.001	0.999	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.999	0.001
R45.8 Other symptoms and signs involving emotional state	0.001	0.999	0.000
T18.2 Foreign body in stomach	0.000	0.999	0.001
T40.3 Methadone	0.000	0.999	0.001
C67.8 Overlapping lesion of bladder	0.001	0.999	0.000
C67.4 Posterior wall of bladder	0.001	0.999	0.000
D16.2 Long bones of lower limb	0.001	0.999	0.000
D16.0 Scapula and long bones of upper limb	0.001	0.999	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.001	0.999	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.999	0.001
T40.8 Lysergide [LSD]	0.000	0.999	0.001
T40.7 Cannabis (derivatives)	0.000	0.999	0.001
T40.0 Opium	0.000	0.999	0.001
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.999	0.001
W08.0 Home	0.001	0.999	0.000
D16 Benign neoplasm of bone and articular cartilage	0.001	0.999	0.000
H34 Retinal vascular occlusions	0.001	0.999	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.999	0.001
D16.7 Ribs, sternum and clavicle	0.001	0.999	0.000
H34.0 Transient retinal artery occlusion	0.001	0.999	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.001	0.999	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
R45.2 Unhappiness	0.001	0.999	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
X00.0 Home	0.000	0.999	0.001
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.001	0.999	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.001	0.999	0.000
K08 Other disorders of teeth and supporting structures	0.001	0.999	0.000
M25.37 Other instability of joint (Ankle and foot)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.999	0.001
D16.6 Vertebral column	0.001	0.999	0.000
D37.2 Small intestine	0.001	0.999	0.000
D37.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
T40.1 Heroin	0.000	0.999	0.001
I87 Other disorders of veins	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.999	0.001
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.999	0.001
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.999	0.001
D16.9 Bone and articular cartilage, unspecified	0.001	0.999	0.000
D16.4 Bones of skull and face	0.001	0.999	0.000
G80.0 Spastic cerebral palsy	0.001	0.999	0.000
H34.9 Retinal vascular occlusion, unspecified	0.001	0.999	0.000
H81.2 Vestibular neuronitis	0.001	0.999	0.000
I87.0 Postphlebitic syndrome	0.001	0.999	0.000
S20.3 Other superficial injuries of front wall of thorax	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.000	0.999	0.001
T87.5 Necrosis of amputation stump	0.001	0.999	0.000
T87.2 Complications of other reattached body part	0.001	0.999	0.000
T87.1 Complications of reattached (part of) lower extremity	0.001	0.999	0.000
T87.0 Complications of reattached (part of) upper extremity	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.001	0.999	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.000	0.999	0.001
M11.98 Crystal arthropathy, unspecified (Other)	0.000	0.999	0.001
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.000	0.999	0.001
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M11.94 Crystal arthropathy, unspecified (Hand)	0.000	0.999	0.001
M11.93 Crystal arthropathy, unspecified (Forearm)	0.000	0.999	0.001
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.000	0.999	0.001
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.000	0.999	0.001
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.000	0.999	0.001
M25.73 Osteophyte (Forearm)	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.999	0.001
S82.41 Fracture of fibula alone (open)	0.001	0.999	0.000
D05.0 Lobular carcinoma in situ	0.001	0.999	0.000
D37.3 Appendix	0.001	0.999	0.000
G47.3 Sleep apnoea	0.000	0.999	0.001
G57.1 Meralgia paraesthetica	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.001	0.999	0.000
G91.0 Communicating hydrocephalus	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
S82.4 Fracture of fibula alone	0.001	0.999	0.000
M11.86 Other specified crystal arthropathies (Lower leg)	0.000	0.999	0.001
M25.70 Osteophyte (Multiple sites)	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.999	0.001
E89.2 Postprocedural hypoparathyroidism	0.000	0.999	0.001
G80.8 Other infantile cerebral palsy	0.001	0.999	0.000
G91.8 Other hydrocephalus	0.001	0.999	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.001	0.999	0.000
K08.3 Retained dental root	0.001	0.999	0.000
M11.9 Crystal arthropathy, unspecified	0.000	0.999	0.001
Q39.6 Diverticulum of oesophagus	0.000	0.999	0.001
Q39.4 Oesophageal web	0.000	0.999	0.001
Q43.0 Meckel's diverticulum	0.000	0.999	0.001
T09.0 Superficial injury of trunk, level unspecified	0.000	0.999	0.001
T40.2 Other opioids	0.000	0.999	0.001
Y84.0 Cardiac catheterisation	0.001	0.999	0.000
Z22.5 Carrier of viral hepatitis	0.001	0.999	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
C76.1 Thorax	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations