TreeWAS – Variant ID: rs7215564

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I51.9 Heart disease, unspecified	0.018	0.982	0.000
I51.7 Cardiomegaly	0.017	0.983	0.000
I51 Complications and ill-defined descriptions of heart disease	0.016	0.984	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.013	0.987	0.000
Y43.3 Other antineoplastic drugs	0.000	0.987	0.013
I51.6 Cardiovascular disease, unspecified	0.012	0.988	0.000
I51.4 Myocarditis, unspecified	0.012	0.988	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.011	0.989	0.000
I51.5 Myocardial degeneration	0.011	0.989	0.000
J31.0 Chronic rhinitis	0.010	0.990	0.000
Y43 Primarily systemic agents	0.000	0.990	0.010
I51.8 Other ill-defined heart diseases	0.010	0.990	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.010	0.990	0.000
I51.0 Cardiac septal defect, acquired	0.010	0.990	0.000
Y43.4 Immunosuppressive agents	0.000	0.991	0.009
Y43.0 Antiallergic and antiemetic drugs	0.000	0.992	0.008
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.992	0.008
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.992	0.008
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.992	0.008
Y42.5 Other oestrogens and progestogens	0.000	0.992	0.008
Y43.9 Primarily systemic agent, unspecified	0.000	0.992	0.008
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.992	0.008
Y43.6 Enzymes, not elsewhere classified	0.000	0.992	0.008
Y43.5 Acidifying and alkalising agents	0.000	0.992	0.008
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.992	0.008
Y43.2 Antineoplastic natural products	0.000	0.993	0.007
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.993	0.007
Y52 Agents primarily affecting the cardiovascular system	0.000	0.993	0.007
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.993	0.007
Z86.0 Personal history of other neoplasms	0.000	0.993	0.007
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
Y43.1 Antineoplastic antimetabolites	0.000	0.993	0.007
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.993	0.007
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.993	0.007
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.993	0.006
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.993	0.006
Y52.1 Calcium-channel blockers	0.000	0.994	0.006
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.994	0.006
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.994	0.006
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.994	0.006
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.994	0.006
Y51.0 Anticholinesterase agents	0.000	0.994	0.006
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.994	0.006
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
Y57 Other and unspecified drugs and medicaments	0.000	0.994	0.006
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.994	0.006
Y58 Bacterial vaccines	0.000	0.994	0.006
S01 Open wound of head	0.006	0.994	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.994	0.006
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.994	0.006
Y42.1 Thyroid hormones and substitutes	0.000	0.994	0.006
Y52.7 Peripheral vasodilators	0.000	0.994	0.006
S01.2 Open wound of nose	0.006	0.994	0.000
S01.4 Open wound of cheek and temporomandibular area	0.006	0.994	0.000
Y42.4 Oral contraceptives	0.000	0.994	0.005
Y59 Other and unspecified vaccines and biological substances	0.000	0.994	0.005
S01.7 Multiple open wounds of head	0.005	0.994	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.994	0.005
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.994	0.005
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.994	0.005
S01.8 Open wound of other parts of head	0.005	0.995	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.995	0.005
Y49.2 Other and unspecified antidepressants	0.000	0.995	0.005
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.005	0.995	0.000
Y49.5 Other antipsychotics and neuroleptics	0.000	0.995	0.005
Y42.9 Other and unspecified hormone antagonists	0.000	0.995	0.005
Y55.4 Expectorants	0.000	0.995	0.005
Y42.2 Antithyroid drugs	0.000	0.995	0.005
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.995	0.005
R35 Polyuria	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.995	0.005
J93.9 Pneumothorax, unspecified	0.000	0.995	0.005
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.995	0.005
Y57.8 Other drugs and medicaments	0.000	0.995	0.005
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.995	0.005
S01.9 Open wound of head, part unspecified	0.005	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.000	0.995	0.005
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.995	0.005
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.995	0.005
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.995	0.005
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
Y49.9 Psychotropic drug, unspecified	0.000	0.995	0.005
Y49.7 Psychostimulants with abuse potential	0.000	0.995	0.005
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.995	0.005
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
Y46.5 Valproic acid	0.000	0.995	0.005
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.995	0.005
Y57.6 Other diagnostic agents	0.000	0.995	0.005
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.995	0.005
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.995	0.005
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.995	0.005
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.995	0.005
Y55.5 Anticommon cold drugs	0.000	0.995	0.005
Y55.3 Antitussives	0.000	0.995	0.005
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.995	0.005
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.995	0.005
Y58.0 BCG vaccine	0.000	0.995	0.005
M00.9 Pyogenic arthritis, unspecified	0.000	0.995	0.005
Y55.0 Oxytocic drugs	0.000	0.995	0.004
Y57.7 Vitamins, not elsewhere classified	0.000	0.995	0.004
Y57.4 Pharmaceutical excipients	0.000	0.995	0.004
Y57.3 Alcohol deterrents	0.000	0.995	0.004
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.995	0.004
Y57.1 Lipotropic drugs	0.000	0.995	0.004
Y57.0 Appetite depressants [anorectics]	0.000	0.995	0.004
S01.0 Open wound of scalp	0.005	0.995	0.000
Y46.4 Iminostilbenes	0.000	0.995	0.004
J31.2 Chronic pharyngitis	0.004	0.995	0.000
Y58.9 Other and unspecified bacterial vaccines	0.000	0.995	0.004
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.995	0.004
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.995	0.004
Y58.5 Diphtheria vaccine	0.000	0.995	0.004
Y58.4 Tetanus vaccine	0.000	0.995	0.004
Y58.3 Plague vaccine	0.000	0.995	0.004
Y58.2 Cholera vaccine	0.000	0.995	0.004
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.995	0.004
Y57.9 Drug or medicament, unspecified	0.000	0.995	0.004
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.996	0.004
Y48 Anaesthetics and therapeutic gases	0.000	0.996	0.004
Y46.8 Antispasticity drugs	0.000	0.996	0.004
Y46.3 Deoxybarbiturates	0.000	0.996	0.004
Y46.1 Oxazolidinediones	0.000	0.996	0.004
Y46.0 Succinimides	0.000	0.996	0.004
Y50.9 Central nervous system stimulant, unspecified	0.000	0.996	0.004
Y50.8 Other central nervous system stimulants	0.000	0.996	0.004
Y50.1 Opioid receptor antagonists	0.000	0.996	0.004
Y50.0 Analeptics	0.000	0.996	0.004
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
Y59.3 Immunoglobulin	0.000	0.996	0.004
Y46.6 Other and unspecified antiepileptics	0.000	0.996	0.004
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.996	0.004
Y57.5 X-ray contrast media	0.000	0.996	0.004
Y59.9 Vaccine or biological substance, unspecified	0.000	0.996	0.004
Y59.8 Other specified vaccines and biological substances	0.000	0.996	0.004
Y59.2 Protozoal vaccines	0.000	0.996	0.004
Y59.1 Rickettsial vaccines	0.000	0.996	0.004
Y46.2 Hydantoin derivatives	0.000	0.996	0.004
S01.5 Open wound of lip and oral cavity	0.004	0.996	0.000
Y41.0 Sulphonamides	0.000	0.996	0.004
Y44.5 Thrombolytic drugs	0.000	0.996	0.004
Y53.3 Saline and osmotic laxatives	0.000	0.996	0.004
S01.1 Open wound of eyelid and periocular area	0.004	0.996	0.000
C32.9 Larynx, unspecified	0.000	0.996	0.004
Y54.3 Benzothiadiazine derivatives	0.000	0.996	0.004
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.996	0.004
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.996	0.004
Y56.3 Emollients, demulcents and protectants	0.000	0.996	0.004
J31.1 Chronic nasopharyngitis	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.996	0.004
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.996	0.004
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.996	0.004
Y47.4 Bromine compounds	0.000	0.996	0.004
Y47.3 Paraldehyde	0.000	0.996	0.004
Y47.2 Chloral derivatives	0.000	0.996	0.004
Y47.0 Barbiturates, not elsewhere classified	0.000	0.996	0.004
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
Y53.7 Emetics	0.000	0.996	0.004
Y53.5 Digestants	0.000	0.996	0.004
Y53.2 Stimulant laxatives	0.000	0.996	0.004
Y53.0 Histamine H2-receptor antagonists	0.000	0.996	0.004
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.996	0.004
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
Y41.4 Anthelminthics	0.000	0.996	0.004
Y41.3 Other antiprotozoal drugs	0.000	0.996	0.004
Y46.7 Anti-Parkinsonism drugs	0.000	0.996	0.004
Y59.0 Viral vaccines	0.000	0.996	0.004
Y54.4 Loop [high-ceiling] diuretics	0.000	0.996	0.004
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.996	0.004
Y44.7 Plasma substitutes	0.000	0.996	0.004
Y44.6 Natural blood and blood products	0.000	0.996	0.004
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.996	0.004
Z94.8 Other transplanted organ and tissue status	0.000	0.996	0.004
Y53.6 Antidiarrhoeal drugs	0.000	0.996	0.004
J44 Other chronic obstructive pulmonary disease	0.000	0.996	0.004
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
Y54.7 Agents affecting calcification	0.000	0.996	0.004
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.996	0.004
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.996	0.004
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
Y54.9 Mineral salts, not elsewhere classified	0.000	0.996	0.004
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.996	0.004
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.996	0.004
Y56.9 Topical agent, unspecified	0.000	0.996	0.003
Y56.8 Other topical agents	0.000	0.996	0.003
Y56.7 Dental drugs, topically applied	0.000	0.996	0.003
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.003
Y56.5 Ophthalmological drugs and preparations	0.000	0.996	0.003
Y56.2 Local astringents and local detergents	0.000	0.996	0.003
Y56.1 Antipruritics	0.000	0.996	0.003
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.996	0.004
Y41.1 Antimycobacterial drugs	0.000	0.996	0.004
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.996	0.004
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.996	0.004
Y53.4 Other laxatives	0.000	0.996	0.003
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.996	0.004
S01.3 Open wound of ear	0.004	0.996	0.000
Y41.5 Antiviral drugs	0.000	0.996	0.003
J93 Pneumothorax	0.000	0.996	0.004
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.003
M16.9 Coxarthrosis, unspecified	0.004	0.996	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.996	0.003
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.996	0.003
Y54.0 Mineralocorticoids	0.000	0.996	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.996	0.003
I33.0 Acute and subacute infective endocarditis	0.000	0.997	0.003
Y48.5 Therapeutic gases	0.000	0.997	0.003
Y48.1 Parenteral anaesthetics	0.000	0.997	0.003
Y48.0 Inhaled anaesthetics	0.000	0.997	0.003
Y47.1 Benzodiazepines	0.000	0.997	0.003
J43.9 Emphysema, unspecified	0.000	0.997	0.003
Y54.5 Other diuretics	0.000	0.997	0.003
Y54.8 Agents affecting uric acid metabolism	0.000	0.997	0.003
Y48.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.997	0.003
Y44.2 Anticoagulants	0.000	0.997	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
J15.1 Pneumonia due to Pseudomonas	0.000	0.997	0.003
Y48.3 Local anaesthetics	0.000	0.997	0.003
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
Y48.4 Anaesthetic, unspecified	0.000	0.997	0.003
M00 Pyogenic arthritis	0.000	0.997	0.003
J93.0 Spontaneous tension pneumothorax	0.000	0.997	0.003
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
J93.8 Other pneumothorax	0.000	0.997	0.003
Y40 Systemic antibiotics	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
C32.0 Glottis	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
J43 Emphysema	0.000	0.997	0.003
J43.2 Centrilobular emphysema	0.000	0.997	0.003
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.997	0.003
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.997	0.002
R04.2 Haemoptysis	0.003	0.997	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
Y60.0 During surgical operation	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.997	0.003
C77.9 Lymph node, unspecified	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.002
M00.0 Staphylococcal arthritis and polyarthritis	0.000	0.997	0.002
Y45.4 Antirheumatics	0.000	0.997	0.002
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.997	0.002
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.997	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.997	0.002
Y40.5 Aminoglycosides	0.000	0.998	0.002
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.000	0.998	0.002
J15.5 Pneumonia due to Escherichia coli	0.000	0.998	0.002
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.998	0.002
M00.2 Other streptococcal arthritis and polyarthritis	0.000	0.998	0.002
M00.1 Pneumococcal arthritis and polyarthritis	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
Y40.2 Chloramphenicol group	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
J43.8 Other emphysema	0.000	0.998	0.002
Y40.4 Tetracyclines	0.000	0.998	0.002
J91 Pleural effusion in conditions classified elsewhere	0.000	0.998	0.002
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
R74 Abnormal serum enzyme levels	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.002
J43.1 Panlobular emphysema	0.000	0.998	0.002
J43.0 MacLeod's syndrome	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
J15.3 Pneumonia due to streptococcus, group B	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
Y40.6 Rifamycins	0.000	0.998	0.002
J15.8 Other bacterial pneumonia	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
Y40.3 Macrolides	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.998	0.002
K86.2 Cyst of pancreas	0.000	0.998	0.002
Y45.1 Salicylates	0.000	0.998	0.002
J90-J94 Other diseases of pleura	0.000	0.998	0.002
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.000	0.998	0.002
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.000	0.998	0.002
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.000	0.998	0.002
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.000	0.998	0.002
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.000	0.998	0.002
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.000	0.998	0.002
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.000	0.998	0.002
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.000	0.998	0.002
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.000	0.998	0.002
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.000	0.998	0.002
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.998	0.002
J94 Other pleural conditions	0.000	0.998	0.002
H52.2 Astigmatism	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)	0.000	0.998	0.002
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)	0.000	0.998	0.002
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)	0.000	0.998	0.002
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)	0.000	0.998	0.002
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)	0.000	0.998	0.002
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)	0.000	0.998	0.002
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)	0.000	0.998	0.002
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)	0.000	0.998	0.002
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.000	0.998	0.002
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)	0.000	0.998	0.002
M00.18 Pneumococcal arthritis and polyarthritis (Other)	0.000	0.998	0.002
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)	0.000	0.998	0.002
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)	0.000	0.998	0.002
M00.15 Pneumococcal arthritis and polyarthritis (Pelvic region and thigh)	0.000	0.998	0.002
M00.14 Pneumococcal arthritis and polyarthritis (Hand)	0.000	0.998	0.002
M00.13 Pneumococcal arthritis and polyarthritis (Forearm)	0.000	0.998	0.002
M00.12 Pneumococcal arthritis and polyarthritis (Upper arm)	0.000	0.998	0.002
M00.11 Pneumococcal arthritis and polyarthritis (Shoulder region)	0.000	0.998	0.002
M00.10 Pneumococcal arthritis and polyarthritis (Multiple sites)	0.000	0.998	0.002
M00.29 Other streptococcal arthritis and polyarthritis (Site unspecified)	0.000	0.998	0.002
M00.28 Other streptococcal arthritis and polyarthritis (Other)	0.000	0.998	0.002
M00.27 Other streptococcal arthritis and polyarthritis (Ankle and foot)	0.000	0.998	0.002
M00.26 Other streptococcal arthritis and polyarthritis (Lower leg)	0.000	0.998	0.002
M00.25 Other streptococcal arthritis and polyarthritis (Pelvic region and thigh)	0.000	0.998	0.002
M00.24 Other streptococcal arthritis and polyarthritis (Hand)	0.000	0.998	0.002
M00.23 Other streptococcal arthritis and polyarthritis (Forearm)	0.000	0.998	0.002
M00.22 Other streptococcal arthritis and polyarthritis (Upper arm)	0.000	0.998	0.002
M00.21 Other streptococcal arthritis and polyarthritis (Shoulder region)	0.000	0.998	0.002
M00.20 Other streptococcal arthritis and polyarthritis (Multiple sites)	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
D41.0 Kidney	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
H57.0 Anomalies of pupillary function	0.000	0.998	0.002
D48.1 Connective and other soft tissue	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.000	0.998	0.002
J94.9 Pleural condition, unspecified	0.000	0.998	0.002
J94.1 Fibrothorax	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.998	0.002
H61.2 Impacted cerumen	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
F31 Bipolar affective disorder	0.000	0.998	0.002
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
J94.0 Chylous effusion	0.000	0.998	0.002
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
Y40.0 Penicillins	0.000	0.998	0.002
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
C77.5 Intrapelvic lymph nodes	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.001	0.998	0.000
F30 Manic episode	0.000	0.998	0.002
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.001
J90 Pleural effusion, not elsewhere classified	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.998	0.002
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.000	0.998	0.002
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
J94.2 Haemothorax	0.000	0.998	0.001
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.001
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.998	0.001
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.998	0.001
R79.0 Abnormal level of blood mineral	0.000	0.998	0.001
S81.0 Open wound of knee	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
F30.9 Manic episode, unspecified	0.000	0.998	0.001
F31.8 Other bipolar affective disorders	0.000	0.998	0.001
F34.1 Dysthymia	0.000	0.998	0.001
H50 Other strabismus	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.001
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.001
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.000	0.999	0.001
M06.0 Seronegative rheumatoid arthritis	0.000	0.999	0.001
M18.1 Other primary arthrosis of first carpometacarpal joint	0.001	0.999	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.999	0.001
I27 Other pulmonary heart diseases	0.000	0.999	0.001
H50.6 Mechanical strabismus	0.001	0.999	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.999	0.001
Y60.4 During endoscopic examination	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.999	0.001
F30.8 Other manic episodes	0.000	0.999	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.999	0.001
S81.8 Open wound of other parts of lower leg	0.001	0.999	0.000
Z32.1 Pregnancy confirmed	0.000	0.999	0.001
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
F30.1 Mania without psychotic symptoms	0.000	0.999	0.001
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.999	0.001
F34.0 Cyclothymia	0.000	0.999	0.001
H50.3 Intermittent heterotropia	0.001	0.999	0.000
Y60.9 During unspecified surgical and medical care	0.001	0.999	0.000
Y60.7 During administration of enema	0.001	0.999	0.000
Y60.3 During injection or immunisation	0.001	0.999	0.000
Y60.2 During kidney dialysis or other perfusion	0.001	0.999	0.000
Y60.1 During infusion or transfusion	0.001	0.999	0.000
H20 Iridocyclitis	0.000	0.999	0.001
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.001	0.999	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
F30.2 Mania with psychotic symptoms	0.000	0.999	0.001
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
R76.2 False-positive serological test for syphilis	0.000	0.999	0.001
R76.1 Abnormal reaction to tuberculin test	0.000	0.999	0.001
Y60.8 During other surgical and medical care	0.001	0.999	0.000
F34 Persistent mood [affective] disorders	0.000	0.999	0.001
G93 Other disorders of brain	0.001	0.999	0.000
H51 Other disorders of binocular movement	0.001	0.999	0.000
C62.9 Testis, unspecified	0.000	0.999	0.001
D69.4 Other primary thrombocytopenia	0.000	0.999	0.001
D69.0 Allergic purpura	0.000	0.999	0.001
E85.8 Other amyloidosis	0.000	0.999	0.001
M07.30 Other psoriatic arthropathies (Multiple sites)	0.001	0.999	0.000
C93.1 Chronic monocytic leukaemia	0.000	0.999	0.001
H51.2 Internuclear ophthalmoplegia	0.001	0.999	0.000
R76.0 Raised antibody titer	0.000	0.999	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.001	0.999	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.001	0.999	0.000
Y60.5 During heart catheterisation	0.001	0.999	0.000
E85 Amyloidosis	0.000	0.999	0.001
M00-M03 Infectious arthropathies	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.999	0.000
C81.1 Nodular sclerosis	0.000	0.999	0.001
D48.5 Skin	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.999	0.001
H50.8 Other specified strabismus	0.001	0.999	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.999	0.001
N40 Hyperplasia of prostate	0.001	0.999	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.999	0.001
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
D68.1 Hereditary factor XI deficiency	0.000	0.999	0.001
D69.2 Other nonthrombocytopenic purpura	0.000	0.999	0.001
I27.1 Kyphoscoliotic heart disease	0.000	0.999	0.001
H52 Disorders of refraction and accommodation	0.001	0.999	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.999	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations