TreeWAS – Variant ID: rs7226371

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.114	0.886	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.086	0.914	0.000
I10-I15 Hypertensive diseases	0.061	0.939	0.000
I11 Hypertensive heart disease	0.056	0.944	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.050	0.950	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.048	0.952	0.000
I15 Secondary hypertension	0.046	0.954	0.000
I13 Hypertensive heart and renal disease	0.044	0.956	0.000
I15.9 Seconday hypertension, unspecified	0.034	0.966	0.000
I15.1 Hypertension secondary to other renal disorders	0.034	0.966	0.000
J44 Other chronic obstructive pulmonary disease	0.034	0.966	0.000
I15.8 Other secondary hypertension	0.033	0.967	0.000
I15.2 Hypertension secondary to endocrine disorders	0.033	0.967	0.000
I15.0 Renovascular hypertension	0.033	0.967	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.032	0.968	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.032	0.968	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.032	0.968	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.032	0.968	0.000
J42 Unspecified chronic bronchitis	0.029	0.971	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.973	0.027
J40-J47 Chronic lower respiratory diseases	0.026	0.974	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.976	0.024
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.023	0.977	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.977	0.023
I12 Hypertensive renal disease	0.023	0.977	0.000
J46 Status asthmaticus	0.022	0.978	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.979	0.021
J41 Simple and mucopurulent chronic bronchitis	0.020	0.980	0.000
J43 Emphysema	0.019	0.981	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.981	0.019
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.981	0.019
J44.8 Other specified chronic obstructive pulmonary disease	0.018	0.982	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.983	0.017
Z35.6 Supervision of very young primigravida	0.000	0.983	0.017
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.983	0.017
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.983	0.017
J41.0 Simple chronic bronchitis	0.016	0.984	0.000
J43.8 Other emphysema	0.016	0.984	0.000
K25.3 Acute without haemorrhage or perforation	0.016	0.984	0.000
R14 Flatulence and related conditions	0.000	0.985	0.015
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.985	0.015
K25.4 Chronic or unspecified with haemorrhage	0.015	0.985	0.000
K25 Gastric ulcer	0.015	0.985	0.000
J43.2 Centrilobular emphysema	0.015	0.985	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.014	0.986	0.000
J41.1 Mucopurulent chronic bronchitis	0.014	0.986	0.000
J43.1 Panlobular emphysema	0.014	0.986	0.000
J43.0 MacLeod's syndrome	0.014	0.986	0.000
I12.9 Hypertensive renal disease without renal failure	0.014	0.986	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.013	0.987	0.000
G56.0 Carpal tunnel syndrome	0.013	0.987	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.013	0.987	0.000
J40 Bronchitis, not specified as acute or chronic	0.013	0.987	0.000
K25.0 Acute with haemorrhage	0.012	0.988	0.000
K25.7 Chronic without haemorrhage or perforation	0.012	0.988	0.000
J43.9 Emphysema, unspecified	0.012	0.988	0.000
K60.3 Anal fistula	0.012	0.988	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.989	0.011
M43.16 Spondylolisthesis (Lumbar region)	0.011	0.989	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.011	0.989	0.000
K25.2 Acute with both haemorrhage and perforation	0.011	0.989	0.000
K25.1 Acute with perforation	0.011	0.989	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.990	0.010
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.990	0.010
K25.5 Chronic or unspecified with perforation	0.009	0.991	0.000
H72 Perforation of tympanic membrane	0.000	0.991	0.009
M43.1 Spondylolisthesis	0.008	0.991	0.000
J45 Asthma	0.008	0.992	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.008	0.992	0.000
K60.2 Anal fissure, unspecified	0.008	0.992	0.000
J47 Bronchiectasis	0.007	0.993	0.000
Y57.9 Drug or medicament, unspecified	0.007	0.993	0.000
K60 Fissure and fistula of anal and rectal regions	0.007	0.993	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.993	0.006
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.006	0.994	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.006	0.994	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.006	0.994	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.006	0.994	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.994	0.006
J45.8 Mixed asthma	0.006	0.994	0.000
J45.1 Nonallergic asthma	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
M43.12 Spondylolisthesis (Cervical region)	0.006	0.994	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.994	0.006
H72.8 Other perforations of tympanic membrane	0.000	0.994	0.006
Y57 Other and unspecified drugs and medicaments	0.006	0.994	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.006	0.994	0.000
M81.98 Osteoporosis, unspecified (Other)	0.006	0.994	0.000
K62.7 Radiation proctitis	0.006	0.994	0.000
R47.0 Dysphasia and aphasia	0.000	0.994	0.006
S02.20 Fracture of nasal bones (closed)	0.000	0.995	0.005
Z29.2 Other prophylactic chemotherapy	0.005	0.995	0.000
Y57.8 Other drugs and medicaments	0.005	0.995	0.000
K60.4 Rectal fistula	0.005	0.995	0.000
M43 Other deforming dorsopathies	0.005	0.995	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.995	0.005
K60.0 Acute anal fissure	0.005	0.995	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.995	0.000
Y57.4 Pharmaceutical excipients	0.004	0.995	0.000
Y57.3 Alcohol deterrents	0.004	0.995	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.995	0.000
Y57.1 Lipotropic drugs	0.004	0.995	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.995	0.000
Z82.3 Family history of stroke	0.004	0.996	0.000
Y57.6 Other diagnostic agents	0.004	0.996	0.000
K60.5 Anorectal fistula	0.004	0.996	0.000
N18.5 Chronic kidney disease, stage 5	0.004	0.996	0.000
M43.6 Torticollis	0.004	0.996	0.000
M43.9 Deforming dorsopathy, unspecified	0.003	0.996	0.000
M43.8 Other specified deforming dorsopathies	0.003	0.996	0.000
M43.5 Other recurrent vertebral subluxation	0.003	0.996	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.003	0.996	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.003	0.996	0.000
M43.2 Other fusion of spine	0.003	0.996	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.996	0.004
M43.0 Spondylolysis	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.004	0.996	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.997	0.003
J45.9 Asthma, unspecified	0.003	0.997	0.000
L98.0 Pyogenic granuloma	0.003	0.997	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.997	0.003
I24.9 Acute ischaemic heart disease, unspecified	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
I84.2 Internal haemorrhoids without complication	0.003	0.997	0.000
M43.06 Spondylolysis (Lumbar region)	0.003	0.997	0.000
M43.62 Torticollis-Cervical	0.003	0.997	0.000
M43.69 Torticollis-Site unspe	0.003	0.997	0.000
M43.68 Torticollis-Sacral/sacrococ	0.003	0.997	0.000
M43.67 Torticollis-Lumbosacral	0.003	0.997	0.000
M43.66 Torticollis-Lumbar	0.003	0.997	0.000
M43.65 Torticollis-Thoracolumbar	0.003	0.997	0.000
M43.64 Torticollis-Thoracic	0.003	0.997	0.000
M43.63 Torticollis-Cervicothoracic	0.003	0.997	0.000
M43.61 Torticollis-Occipit-atl-axl	0.003	0.997	0.000
M43.60 Torticollis-Mult site	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
M43.29 Other fusion of spine (Site unspecified)	0.003	0.997	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.003	0.997	0.000
M43.26 Other fusion of spine (Lumbar region)	0.003	0.997	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.003	0.997	0.000
M43.24 Other fusion of spine (Thoracic region)	0.003	0.997	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.003	0.997	0.000
M43.22 Other fusion of spine (Cervical region)	0.003	0.997	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.003	0.997	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.003	0.997	0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.003	0.997	0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.003	0.997	0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.003	0.997	0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.003	0.997	0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.003	0.997	0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.003	0.997	0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.003	0.997	0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.003	0.997	0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.003	0.997	0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.003	0.997	0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.003	0.997	0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.003	0.997	0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.003	0.997	0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.003	0.997	0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.003	0.997	0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.003	0.997	0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.003	0.997	0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.003	0.997	0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.003	0.997	0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.003	0.997	0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.003	0.997	0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.003	0.997	0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.003	0.997	0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.003	0.997	0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.003	0.997	0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.003	0.997	0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.003	0.997	0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.003	0.997	0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.003	0.997	0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.003	0.997	0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.003	0.997	0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.003	0.997	0.000
M43.82 Other specified deforming dorsopathies (Cervical region)	0.003	0.997	0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.003	0.997	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.003	0.997	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.003	0.997	0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.003	0.997	0.000
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.003	0.997	0.000
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.003	0.997	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.003	0.997	0.000
M43.04 Spondylolysis (Thoracic region)	0.003	0.997	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.003	0.997	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M43.09 Spondylolysis (Site unspecified)	0.003	0.997	0.000
K60.1 Chronic anal fissure	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
M43.02 Spondylolysis (Cervical region)	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
Z39.1 Care and examination of lactating mother	0.000	0.997	0.003
Z39 Postpartum care and examination	0.000	0.997	0.003
M25.46 Effusion of joint (Lower leg)	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
J45.0 Predominantly allergic asthma	0.002	0.997	0.000
W19.4 Street and highway	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
Y40 Systemic antibiotics	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
W19.1 Residential institution	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.002	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.002	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.002
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Z39.2 Routine postpartum follow-up	0.000	0.998	0.002
W19 Unspecified fall	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.998	0.002
X62.9 Unspecified place	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.998	0.002
S00.1 Contusion of eyelid and periocular area	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
S01.8 Open wound of other parts of head	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
G56 Mononeuropathies of upper limb	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
W19.8 Other specified place	0.002	0.998	0.000
W19.5 Trade and service area	0.002	0.998	0.000
W19.0 Home	0.002	0.998	0.000
W19.7 Farm	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
Z29 Need for other prophylactic measures	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
W19.6 Industrial and construction area	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y54.7 Agents affecting calcification	0.001	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.998	0.001
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.998	0.001
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.998	0.001
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.998	0.001
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.998	0.001
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.998	0.001
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.998	0.001
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.998	0.001
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.998	0.001
W19.3 Sports and athletics area	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
M40-M43 Deforming dorsopathies	0.002	0.998	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.002	0.998	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.001	0.998	0.000
M21.2 Flexion deformity	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.001	0.998	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.001	0.998	0.000
L98.5 Mucinosis of skin	0.001	0.998	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.001	0.998	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.001	0.998	0.000
L98.1 Factitial dermatitis	0.001	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.002	0.998	0.000
Z82.1 Family history of blindness and visual loss	0.001	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.001	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
C45.7 Mesothelioma of other sites	0.000	0.998	0.001
C78.7 Secondary malignant neoplasm of liver	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.998	0.000
G56.3 Lesion of radial nerve	0.001	0.998	0.000
T17.3 Foreign body in larynx	0.001	0.998	0.000
T88.4 Failed or difficult intubation	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.998	0.001
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.998	0.001
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.001
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.001
G56.4 Causalgia	0.001	0.998	0.000
Z90.0 Acquired absence of part of head and neck	0.001	0.998	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.999	0.001
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
Z29.9 Prophylactic measure, unspecified	0.001	0.999	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
W19.09 Unspecified fall; Home; During unspecified activity	0.001	0.999	0.000
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.001	0.999	0.000
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.001	0.999	0.000
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.001	0.999	0.000
E87.7 Fluid overload	0.001	0.999	0.000
F10.2 Dependence syndrome	0.001	0.999	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.999	0.001
T18.0 Foreign body in mouth	0.001	0.999	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.999	0.001
Z82.2 Family history of deafness and hearing loss	0.001	0.999	0.000
M21.26 Flexion deformity (Lower leg)	0.000	0.999	0.001
C45.2 Mesothelioma of pericardium	0.000	0.999	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.999	0.001
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.999	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
M21 Other acquired deformities of limbs	0.000	0.999	0.001
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.000	0.999	0.001
E16.2 Hypoglycaemia, unspecified	0.001	0.999	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.001	0.999	0.000
Y45.8 Other analgesics and antipyretics	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
M42 Spinal osteochondrosis	0.001	0.999	0.000
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations