TreeWAS – Variant ID: rs72480748

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.664	0.336	0.000
C34 Malignant neoplasm of bronchus and lung	0.660	0.340	0.000
C34.3 Lower lobe, bronchus or lung	0.621	0.379	0.000
C34.0 Main bronchus	0.600	0.400	0.000
C34.1 Upper lobe, bronchus or lung	0.579	0.421	0.000
C34.2 Middle lobe, bronchus or lung	0.546	0.454	0.000
C34.8 Overlapping lesion of bronchus and lung	0.509	0.491	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.344	0.656	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.309	0.691	0.000
C30.0 Nasal cavity	0.285	0.715	0.000
C33 Malignant neoplasm of trachea	0.263	0.737	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.247	0.753	0.000
C31 Malignant neoplasm of accessory sinuses	0.247	0.753	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.235	0.765	0.000
C30.1 Middle ear	0.222	0.778	0.000
C37 Malignant neoplasm of thymus	0.208	0.792	0.000
C32 Malignant neoplasm of larynx	0.207	0.793	0.000
C31.9 Accessory sinus, unspecified	0.177	0.823	0.000
C31.8 Overlapping lesion of accessory sinuses	0.177	0.823	0.000
C31.3 Sphenoidal sinus	0.177	0.823	0.000
C31.2 Frontal sinus	0.177	0.823	0.000
C31.1 Ethmoidal sinus	0.177	0.823	0.000
C31.0 Maxillary sinus	0.177	0.823	0.000
C39.9 Ill-defined sites within the respiratory system	0.177	0.823	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.177	0.823	0.000
C39.0 Upper respiratory tract, part unspecified	0.177	0.823	0.000
C38.3 Mediastinum, part unspecified	0.170	0.829	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.168	0.831	0.000
C38.2 Posterior mediastinum	0.168	0.831	0.000
C38.1 Anterior mediastinum	0.168	0.831	0.000
C38.0 Heart	0.168	0.831	0.000
C32.3 Laryngeal cartilage	0.165	0.835	0.000
C38.4 Pleura	0.154	0.846	0.000
C32.8 Overlapping lesion of larynx	0.148	0.851	0.000
C32.2 Subglottis	0.148	0.851	0.000
C32.1 Supraglottis	0.139	0.861	0.000
C32.0 Glottis	0.135	0.865	0.000
C32.9 Larynx, unspecified	0.109	0.890	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.033	0.967	0.000
Y52 Agents primarily affecting the cardiovascular system	0.031	0.969	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.029	0.971	0.000
Y52.1 Calcium-channel blockers	0.027	0.973	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.026	0.974	0.000
Y52.7 Peripheral vasodilators	0.026	0.974	0.000
C01 Malignant neoplasm of base of tongue	0.026	0.974	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.025	0.975	0.000
S92.00 Fracture of calcaneus (closed)	0.025	0.975	0.000
S92.0 Fracture of calcaneus	0.024	0.976	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.024	0.976	0.000
C09 Malignant neoplasm of tonsil	0.024	0.976	0.000
C10 Malignant neoplasm of oropharynx	0.024	0.976	0.000
S92 Fracture of foot, except ankle	0.024	0.976	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.024	0.976	0.000
C13 Malignant neoplasm of hypopharynx	0.023	0.977	0.000
C11 Malignant neoplasm of nasopharynx	0.023	0.977	0.000
C10.9 Oropharynx, unspecified	0.023	0.977	0.000
C09.9 Tonsil, unspecified	0.023	0.977	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.022	0.978	0.000
S92.2 Fracture of other tarsal bone(s)	0.022	0.978	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.021	0.978	0.000
S92.1 Fracture of talus	0.021	0.979	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.021	0.979	0.000
C03 Malignant neoplasm of gum	0.021	0.979	0.000
C00 Malignant neoplasm of lip	0.021	0.979	0.000
C11.9 Nasopharynx, unspecified	0.021	0.979	0.000
S92.7 Multiple fractures of foot	0.021	0.979	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.021	0.979	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.020	0.980	0.000
C04 Malignant neoplasm of floor of mouth	0.020	0.980	0.000
C13.0 Postcricoid region	0.020	0.980	0.000
S92.10 Fracture of talus (closed)	0.020	0.980	0.000
S92.01 Fracture of calcaneus (open)	0.020	0.980	0.000
Z36 Antenatal screening	0.020	0.980	0.000
C13.9 Hypopharynx, unspecified	0.019	0.980	0.000
S92.4 Fracture of great toe	0.019	0.981	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.019	0.981	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.019	0.981	0.000
S92.3 Fracture of metatarsal bone	0.019	0.981	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.018	0.981	0.000
C12 Malignant neoplasm of pyriform sinus	0.018	0.981	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.018	0.982	0.000
S92.70 Multiple fractures of foot (closed)	0.018	0.982	0.000
C06.0 Cheek mucosa	0.018	0.982	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.018	0.982	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.018	0.982	0.000
C09.8 Overlapping lesion of tonsil	0.017	0.982	0.000
C09.0 Tonsillar fossa	0.017	0.982	0.000
C10.8 Overlapping lesion of oropharynx	0.017	0.982	0.000
C10.4 Branchial cleft	0.017	0.982	0.000
C10.3 Posterior wall of oropharynx	0.017	0.982	0.000
C10.2 Lateral wall of oropharynx	0.017	0.982	0.000
C10.1 Anterior surface of epiglottis	0.017	0.982	0.000
C10.0 Vallecula	0.017	0.982	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.982	0.018
Z36.9 Antenatal screening, unspecified	0.017	0.983	0.000
S92.9 Fracture of foot, unspecified	0.017	0.983	0.000
C00.1 External lower lip	0.017	0.983	0.000
C13.8 Overlapping lesion of hypopharynx	0.017	0.983	0.000
C13.2 Posterior wall of hypopharynx	0.017	0.983	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.017	0.983	0.000
C08.9 Major salivary gland, unspecified	0.017	0.983	0.000
S92.41 Fracture of great toe (open)	0.017	0.983	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.017	0.983	0.000
C03.1 Lower gum	0.017	0.983	0.000
C05 Malignant neoplasm of palate	0.017	0.983	0.000
C11.8 Overlapping lesion of nasopharynx	0.017	0.983	0.000
C11.3 Anterior wall of nasopharynx	0.017	0.983	0.000
C11.2 Lateral wall of nasopharynx	0.017	0.983	0.000
C11.1 Posterior wall of nasopharynx	0.017	0.983	0.000
C11.0 Superior wall of nasopharynx	0.017	0.983	0.000
S92.5 Fracture of other toe	0.017	0.983	0.000
C06.2 Retromolar area	0.016	0.984	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.016	0.984	0.000
C04.9 Floor of mouth, unspecified	0.016	0.984	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.016	0.984	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.016	0.984	0.000
C06.1 Vestibule of mouth	0.016	0.984	0.000
C02.9 Tongue, unspecified	0.016	0.984	0.000
C08.0 Submandibular gland	0.016	0.984	0.000
C00.0 External upper lip	0.015	0.984	0.000
S92.11 Fracture of talus (open)	0.015	0.984	0.000
C08.8 Overlapping lesion of major salivary glands	0.015	0.985	0.000
C08.1 Sublingual gland	0.015	0.985	0.000
C03.9 Gum, unspecified	0.015	0.985	0.000
C03.0 Upper gum	0.015	0.985	0.000
C00.8 Overlapping lesion of lip	0.015	0.985	0.000
C00.6 Commissure of lip	0.015	0.985	0.000
C00.5 Lip, unspecified, inner aspect	0.015	0.985	0.000
C00.4 Lower lip, inner aspect	0.015	0.985	0.000
C00.3 Upper lip, inner aspect	0.015	0.985	0.000
C00.2 External lip, unspecified	0.015	0.985	0.000
S92.71 Multiple fractures of foot (open)	0.015	0.985	0.000
C06.9 Mouth, unspecified	0.015	0.985	0.000
S92.30 Fracture of metatarsal bone (closed)	0.015	0.985	0.000
C04.8 Overlapping lesion of floor of mouth	0.015	0.985	0.000
C04.1 Lateral floor of mouth	0.015	0.985	0.000
C04.0 Anterior floor of mouth	0.015	0.985	0.000
Z36.5 Antenatal screening for isoimmunisation	0.014	0.986	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.014	0.986	0.000
C00.9 Lip, unspecified	0.014	0.986	0.000
S92.51 Fracture of other toe (open)	0.014	0.986	0.000
S92.31 Fracture of metatarsal bone (open)	0.013	0.986	0.000
C02.2 Ventral surface of tongue	0.013	0.986	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.013	0.986	0.000
C14.2 Waldeyer's ring	0.013	0.986	0.000
C02.8 Overlapping lesion of tongue	0.013	0.987	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.013	0.987	0.000
C02.0 Dorsal surface of tongue	0.013	0.987	0.000
Z36.8 Other antenatal screening	0.013	0.987	0.000
C14.0 Pharynx, unspecified	0.013	0.987	0.000
S92.91 Fracture of foot, unspecified (open)	0.012	0.987	0.000
S92.90 Fracture of foot, unspecified (closed)	0.012	0.987	0.000
S92.40 Fracture of great toe (closed)	0.012	0.988	0.000
C05.9 Palate, unspecified	0.012	0.988	0.000
C05.8 Overlapping lesion of palate	0.012	0.988	0.000
C05.2 Uvula	0.012	0.988	0.000
C05.0 Hard palate	0.012	0.988	0.000
C02.4 Lingual tonsil	0.011	0.988	0.000
C05.1 Soft palate	0.010	0.990	0.000
S92.50 Fracture of other toe (closed)	0.009	0.991	0.000
C07 Malignant neoplasm of parotid gland	0.008	0.991	0.001
C02.1 Border of tongue	0.008	0.992	0.000
S82.60 Fracture of lateral malleolus (closed)	0.008	0.992	0.000
R40.0 Somnolence	0.007	0.993	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.993	0.007
S80.0 Contusion of knee	0.007	0.993	0.000
I78.1 Naevus, nonneoplastic	0.000	0.994	0.006
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.005	0.995	0.000
E11.2 With renal complications	0.000	0.995	0.005
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.995	0.005
K56.5 Intestinal adhesions [bands] with obstruction	0.005	0.995	0.000
I95.2 Hypotension due to drugs	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
R40 Somnolence, stupor and coma	0.004	0.996	0.000
R40.2 Coma, unspecified	0.004	0.996	0.000
S82.6 Fracture of lateral malleolus	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.004	0.996	0.000
H16.0 Corneal ulcer	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
S80.7 Multiple superficial injuries of lower leg	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
K50.9 Crohn's disease, unspecified	0.004	0.996	0.000
H25.8 Other senile cataract	0.000	0.996	0.004
O82.0 Delivery by elective Caesarean section	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
U51 Admission status on psychiatric patients	0.003	0.996	0.000
E27 Other disorders of adrenal gland	0.000	0.997	0.003
R22.2 Localised swelling, mass and lump, trunk	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
H00.1 Chalazion	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
R40.1 Stupor	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
H16.9 Keratitis, unspecified	0.003	0.997	0.000
I44.1 Atrioventricular block, second degree	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.997	0.003
C71.1 Frontal lobe	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
N64.8 Other specified disorders of breast	0.000	0.997	0.003
U51.2 Previously admitted to a psychiatric hospital of another provider	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
Y40 Systemic antibiotics	0.003	0.997	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.997	0.000
S93.4 Sprain and strain of ankle	0.002	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.002	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.997	0.000
Y58.0 BCG vaccine	0.002	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.002	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.997	0.000
H16.8 Other keratitis	0.002	0.997	0.000
S82.1 Fracture of upper end of tibia	0.002	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.997	0.000
H16.4 Corneal neovascularisation	0.002	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
Q12.0 Congenital cataract	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
E27.2 Addisonian crisis	0.000	0.998	0.002
U81.0 Vancomycin resistant agent	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.002	0.998	0.000
U06.9 Emergency use of U06.9	0.002	0.998	0.000
U06.8 Emergency use of U06.8	0.002	0.998	0.000
U06.7 Emergency use of U06.7	0.002	0.998	0.000
U06.6 Emergency use of U06.6	0.002	0.998	0.000
U06.5 Emergency use of U06.5	0.002	0.998	0.000
U06.4 Emergency use of U06.4	0.002	0.998	0.000
U06.3 Emergency use of U06.3	0.002	0.998	0.000
U06.2 Emergency use of U06.2	0.002	0.998	0.000
U06.1 Emergency use of U06.1	0.002	0.998	0.000
U06.0 Emergency use of U06.0	0.002	0.998	0.000
U07.9 Emergency use of U07.9	0.002	0.998	0.000
U07.8 Emergency use of U07.8	0.002	0.998	0.000
U07.7 Emergency use of U07.7	0.002	0.998	0.000
U07.6 Emergency use of U07.6	0.002	0.998	0.000
U07.5 Emergency use of U07.5	0.002	0.998	0.000
U07.4 Emergency use of U07.4	0.002	0.998	0.000
U07.3 Emergency use of U07.3	0.002	0.998	0.000
U07.2 Emergency use of U07.2	0.002	0.998	0.000
U07.1 Emergency use of U07.1	0.002	0.998	0.000
U07.0 Emergency use of U07.0	0.002	0.998	0.000
U50.9 Inquest Adjourned Death	0.002	0.998	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.002	0.998	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.002	0.998	0.000
U50.1 Level of care administered to neonates (Special Care)	0.002	0.998	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.001	0.998	0.001
Y54.5 Other diuretics	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
M13.94 Arthritis, unspecified (Hand)	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.002
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
K56.1 Intussusception	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.001	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.998	0.002
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.998	0.000
F06.3 Organic mood [affective] disorders	0.002	0.998	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
M46.4 Discitis, unspecified	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.001	0.998	0.000
S87 Crushing injury of lower leg	0.001	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.001	0.998	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations