TreeWAS – Variant ID: rs72708542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
# Top node	1.000	0.000
C43 Malignant melanoma of skin	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.994	0.006
Chapter I Certain infectious and parasitic diseases	0.991	0.009
A30-A49 Other bacterial diseases	0.990	0.010
D37-D48 Neoplasms of uncertain or unknown behaviour	0.988	0.012
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.985	0.015
Chapter IV Endocrine, nutritional and metabolic diseases	0.984	0.016
D69 Purpura and other haemorrhagic conditions	0.977	0.023
A41 Other septicaemia	0.974	0.026
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.971	0.029
D69.6 Thrombocytopenia, unspecified	0.969	0.031
C44 Other malignant neoplasms of skin	0.969	0.031
Chapter IX Diseases of the circulatory system	0.960	0.040
E50-E64 Other nutritional deficiencies	0.960	0.040
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.957	0.043
C43.5 Malignant melanoma of trunk	0.957	0.043
C43.9 Malignant melanoma of skin, unspecified	0.955	0.045
D86 Sarcoidosis	0.950	0.050
E55 Vitamin D deficiency	0.945	0.055
A49 Bacterial infection of unspecified site	0.945	0.055
C44.3 Skin of other and unspecified parts of face	0.937	0.063
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.936	0.064
E55.9 Vitamin D deficiency, unspecified	0.934	0.066
A41.5 Septicaemia due to other Gram-negative organisms	0.933	0.067
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.931	0.069
D70-D77 Other diseases of blood and blood-forming organs	0.931	0.069
I10-I15 Hypertensive diseases	0.928	0.072
D46 Myelodysplastic syndromes	0.927	0.073
E20-E35 Disorders of other endocrine glands	0.925	0.075
I26 Pulmonary embolism	0.919	0.081
D86.0 Sarcoidosis of lung	0.918	0.082
C34 Malignant neoplasm of bronchus and lung	0.915	0.085
D47.3 Essential (haemorrhagic) thrombocythaemia	0.913	0.087
I70-I79 Diseases of arteries, arterioles and capillaries	0.912	0.088
I12 Hypertensive renal disease	0.911	0.089
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.903	0.097
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.897	0.103
C44.6 Skin of upper limb, including shoulder	0.894	0.106
I12.0 Hypertensive renal disease with renal failure	0.891	0.109
D89.2 Hypergammaglobulinaemia, unspecified	0.886	0.114
D46.9 Myelodysplastic syndrome, unspecified	0.884	0.116
C43.3 Malignant melanoma of other and unspecified parts of face	0.869	0.131
B95-B98 Bacterial, viral and other infectious agents	0.867	0.133
C34.9 Bronchus or lung, unspecified	0.865	0.135
Chapter X Diseases of the respiratory system	0.863	0.137
C50-C50 Malignant neoplasm of breast	0.859	0.141
C79 Secondary malignant neoplasm of other sites	0.858	0.142
C44.4 Skin of scalp and neck	0.857	0.143
C43.6 Malignant melanoma of upper limb, including shoulder	0.856	0.144
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.854	0.146
A41.2 Septicaemia due to unspecified staphylococcus	0.849	0.151
D55-D59 Haemolytic anaemias	0.848	0.152
D84 Other immunodeficiencies	0.848	0.152
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.847	0.153
A49.8 Other bacterial infections of unspecified site	0.846	0.154
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.845	0.155
C43.4 Malignant melanoma of scalp and neck	0.843	0.157
D47.2 Monoclonal gammopathy	0.841	0.159
C34.3 Lower lobe, bronchus or lung	0.839	0.161
A49.9 Bacterial infection, unspecified	0.838	0.162
D70 Agranulocytosis	0.836	0.164
A41.0 Septicaemia due to Staphylococcus aureus	0.833	0.167
E27 Other disorders of adrenal gland	0.827	0.173
E10-E14 Diabetes mellitus	0.827	0.173
I71 Aortic aneurysm and dissection	0.826	0.174
I74 Arterial embolism and thrombosis	0.824	0.176
J90-J94 Other diseases of pleura	0.816	0.184
A40 Streptococcal septicaemia	0.814	0.186
Chapter XXII Codes for special purposes	0.814	0.186
D47.4 Osteomyelofibrosis	0.813	0.187
C79.7 Secondary malignant neoplasm of adrenal gland	0.812	0.188
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.810	0.190
A49.1 Streptococcal infection, unspecified	0.809	0.191
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.803	0.197
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.803	0.197
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.798	0.202
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.795	0.205
C64-C68 Malignant neoplasms of urinary tract	0.787	0.213
D72 Other disorders of white blood cells	0.777	0.223
D80 Immunodeficiency with predominantly antibody defects	0.770	0.230
A41.8 Other specified septicaemia	0.769	0.231
C44.2 Skin of ear and external auricular canal	0.768	0.232
I70 Atherosclerosis	0.767	0.233
B15-B19 Viral hepatitis	0.766	0.234
A15-A19 Tuberculosis	0.766	0.234
E28 Ovarian dysfunction	0.765	0.235
D47.1 Chronic myeloproliferative disease	0.761	0.239
A80-A89 Viral infections of the central nervous system	0.760	0.239
A48 Other bacterial diseases, not elsewhere classified	0.759	0.241
I12.9 Hypertensive renal disease without renal failure	0.759	0.241
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.759	0.241
C50 Malignant neoplasm of breast	0.759	0.241
A50-A64 Infections with a predominantly sexual mode of transmission	0.757	0.243
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.756	0.244
D69.4 Other primary thrombocytopenia	0.756	0.244
D73 Diseases of spleen	0.752	0.248
C50.4 Upper-outer quadrant of breast	0.751	0.249
J93 Pneumothorax	0.751	0.249
E24 Cushing's syndrome	0.750	0.250
D84.8 Other specified immunodeficiencies	0.743	0.257
C32 Malignant neoplasm of larynx	0.738	0.262
E65-E68 Obesity and other hyperalimentation	0.738	0.262
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.738	0.262
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.737	0.263
J95-J99 Other diseases of the respiratory system	0.734	0.266
Q20-Q28 Congenital malformations of the circulatory system	0.730	0.270
C49 Malignant neoplasm of other connective and soft tissue	0.729	0.271
C15-C26 Malignant neoplasms of digestive organs	0.729	0.271
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.727	0.273
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.726	0.274
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.722	0.278
I72 Other aneurysm	0.721	0.279
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.719	0.281
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C30 Malignant neoplasm of nasal cavity and middle ear	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C43.8 Overlapping malignant melanoma of skin	0.716	0.284
C43.2 Malignant melanoma of ear and external auricular canal	0.716	0.284
C43.1 Malignant melanoma of eyelid, including canthus	0.716	0.284
C43.0 Malignant melanoma of lip	0.716	0.284
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.714	0.286
D69.3 Idiopathic thrombocytopenic purpura	0.713	0.287
D83 Common variable immunodeficiency	0.713	0.287
D82 Immunodeficiency associated with other major defects	0.713	0.287
D81 Combined immunodeficiencies	0.713	0.287
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.289
B65-B83 Helminthiases	0.711	0.289
B50-B64 Protozoal diseases	0.711	0.289
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.289
A75-A79 Rickettsioses	0.711	0.289
A70-A74 Other diseases caused by chlamydiae	0.711	0.289
A65-A69 Other spirochaetal diseases	0.711	0.289
A20-A28 Certain zoonotic bacterial diseases	0.711	0.289
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.710	0.290
A44 Bartonellosis	0.709	0.290
A43 Nocardiosis	0.709	0.290
A42 Actinomycosis	0.709	0.290
A39 Meningococcal infection	0.709	0.290
A37 Whooping cough	0.709	0.290
A36 Diphtheria	0.709	0.290
A32 Listeriosis	0.709	0.290
A31 Infection due to other mycobacteria	0.709	0.290
A30 Leprosy [Hansen's disease]	0.709	0.290
A38 Scarlet fever	0.709	0.290
A35 Other tetanus	0.709	0.290
A34 Obstetrical tetanus	0.709	0.290
A33 Tetanus neonatorum	0.709	0.290
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.708	0.292
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.708	0.292
D67 Hereditary factor IX deficiency	0.706	0.293
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.706	0.293
I11 Hypertensive heart disease	0.705	0.295
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.705	0.295
E26 Hyperaldosteronism	0.705	0.295
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.705	0.295
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.704	0.296
I71.0 Dissection of aorta [any part]	0.704	0.296
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.703	0.297
D86.1 Sarcoidosis of lymph nodes	0.702	0.298
D58 Other hereditary haemolytic anaemias	0.702	0.298
E61 Deficiency of other nutrient elements	0.701	0.299
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.700	0.299
D69.9 Haemorrhagic condition, unspecified	0.700	0.300
D69.8 Other specified haemorrhagic conditions	0.700	0.300
D69.2 Other nonthrombocytopenic purpura	0.700	0.300
D69.1 Qualitative platelet defects	0.700	0.300
D69.0 Allergic purpura	0.700	0.300
D68 Other coagulation defects	0.700	0.300
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.699	0.301
A41.4 Septicaemia due to anaerobes	0.698	0.302
A41.3 Septicaemia due to Haemophilus influenzae	0.698	0.302
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.696	0.304
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.696	0.304
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.696	0.304
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.696	0.304
J93.9 Pneumothorax, unspecified	0.695	0.305
C44.8 Overlapping lesion of skin	0.695	0.305
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.695	0.305
E13 Other specified diabetes mellitus	0.694	0.306
C77.0 Lymph nodes of head, face and neck	0.693	0.307
E27.8 Other specified disorders of adrenal gland	0.693	0.307
J60-J70 Lung diseases due to external agents	0.693	0.307
J00-J06 Acute upper respiratory infections	0.691	0.309
A46 Erysipelas	0.691	0.309
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.690	0.309
B20-B24 Human immunodeficiency virus [HIV] disease	0.690	0.310
J92 Pleural plaque	0.689	0.311
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.689	0.311
B90-B94 Sequelae of infectious and parasitic diseases	0.689	0.311
I00-I02 Acute rheumatic fever	0.689	0.311
E64 Sequelae of malnutrition and other nutritional deficiencies	0.689	0.311
E63 Other nutritional deficiencies	0.689	0.311
E56 Other vitamin deficiencies	0.689	0.311
E51 Thiamine deficiency	0.689	0.311
E50 Vitamin A deficiency	0.689	0.311
E60 Dietary zinc deficiency	0.689	0.311
E59 Dietary selenium deficiency	0.689	0.311
E58 Dietary calcium deficiency	0.689	0.311
E54 Ascorbic acid deficiency	0.689	0.311
E52 Niacin deficiency [pellagra]	0.689	0.311
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.687	0.313
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.686	0.313
C38 Malignant neoplasm of heart, mediastinum and pleura	0.686	0.313
C31 Malignant neoplasm of accessory sinuses	0.686	0.313
C37 Malignant neoplasm of thymus	0.686	0.313
C33 Malignant neoplasm of trachea	0.686	0.313
E27.3 Drug-induced adrenocortical insufficiency	0.686	0.314
C44.0 Skin of lip	0.686	0.314
D50-D53 Nutritional anaemias	0.685	0.315
C34.2 Middle lobe, bronchus or lung	0.683	0.317
D86.8 Sarcoidosis of other and combined sites	0.681	0.319
D86.3 Sarcoidosis of skin	0.681	0.319
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.681	0.319
A40.9 Streptococcal septicaemia, unspecified	0.680	0.320
D69.5 Secondary thrombocytopenia	0.679	0.320
E55.0 Rickets, active	0.677	0.322
A49.3 Mycoplasma infection, unspecified	0.677	0.322
A49.2 Haemophilus influenzae infection, unspecified	0.677	0.322
C43.7 Malignant melanoma of lower limb, including hip	0.677	0.323
I27 Other pulmonary heart diseases	0.675	0.325
I05-I09 Chronic rheumatic heart diseases	0.675	0.325
J80-J84 Other respiratory diseases principally affecting the interstitium	0.673	0.327
A41.1 Septicaemia due to other specified staphylococcus	0.671	0.328
I28 Other diseases of pulmonary vessels	0.671	0.329
C79.2 Secondary malignant neoplasm of skin	0.671	0.329
I74.9 Embolism and thrombosis of unspecified artery	0.670	0.330
D59 Acquired haemolytic anaemia	0.669	0.330
D66 Hereditary factor VIII deficiency	0.669	0.331
D89.9 Disorder involving the immune mechanism, unspecified	0.667	0.332
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.667	0.332
D89.3 Immune reconstitution syndrome	0.667	0.332
D89.1 Cryoglobulinaemia	0.667	0.332
D89.0 Polyclonal hypergammaglobulinaemia	0.667	0.332
D74 Methaemoglobinaemia	0.667	0.332
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.667	0.332
D71 Functional disorders of polymorphonuclear neutrophils	0.667	0.332
C77.9 Lymph node, unspecified	0.667	0.333
D72.8 Other specified disorders of white blood cells	0.667	0.333
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.667	0.333
I13 Hypertensive heart and renal disease	0.665	0.335
D46.7 Other myelodysplastic syndromes	0.665	0.335
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.665	0.335
D46.5 Refractory anaemia with multi-lineage dysplasia	0.665	0.335
D46.4 Refractory anaemia, unspecified	0.665	0.335
D46.3 Refractory anaemia with excess of blasts with transformation	0.665	0.335
D46.2 Refractory anaemia with excess of blasts	0.665	0.335
D46.1 Refractory anaemia with sideroblasts	0.665	0.335
D46.0 Refractory anaemia without sideroblasts, so stated	0.665	0.335
J90 Pleural effusion, not elsewhere classified	0.664	0.336
E35 Disorders of endocrine glands in diseases classified elsewhere	0.663	0.336
E32 Diseases of thymus	0.663	0.336
E31 Polyglandular dysfunction	0.663	0.336
E30 Disorders of puberty, not elsewhere classified	0.663	0.336
E25 Adrenogenital disorders	0.663	0.336
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.663	0.337
E34 Other endocrine disorders	0.662	0.337
E20 Hypoparathyroidism	0.662	0.338
C97 Malignant neoplasms of independent (primary) multiple sites	0.662	0.338
R25 Abnormal involuntary movements	0.660	0.340
I15 Secondary hypertension	0.660	0.340
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.659	0.341
E53 Deficiency of other B group vitamins	0.656	0.344
C34.8 Overlapping lesion of bronchus and lung	0.656	0.344
D86.9 Sarcoidosis, unspecified	0.655	0.345
E23 Hypofunction and other disorders of pituitary gland	0.655	0.345
C77.5 Intrapelvic lymph nodes	0.655	0.345
I78 Diseases of capillaries	0.654	0.346
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.653	0.347
J98 Other respiratory disorders	0.652	0.348
J92.0 Pleural plaque with presence of asbestos	0.650	0.350
D73.0 Hyposplenism	0.650	0.350
R26 Abnormalities of gait and mobility	0.646	0.354
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.646	0.354
E21.3 Hyperparathyroidism, unspecified	0.645	0.355
E40-E46 Malnutrition	0.643	0.356
E28.3 Primary ovarian failure	0.643	0.357
C76 Malignant neoplasm of other and ill-defined sites	0.643	0.357
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.642	0.358
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.642	0.358
C26 Malignant neoplasm of other and ill-defined digestive organs	0.641	0.359
C77.4 Inguinal and lower limb lymph nodes	0.640	0.360
D43.2 Brain, unspecified	0.640	0.360
E29 Testicular dysfunction	0.639	0.361
D43.0 Brain, supratentorial	0.638	0.362
I74.5 Embolism and thrombosis of iliac artery	0.637	0.363
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.635	0.365
B99-B99 Other infectious diseases	0.635	0.365
J20-J22 Other acute lower respiratory infections	0.633	0.367
Q23 Congenital malformations of aortic and mitral valves	0.633	0.367
Q00-Q07 Congenital malformations of the nervous system	0.633	0.367
I70.0 Atherosclerosis of aorta	0.632	0.368
C44.9 Malignant neoplasm of skin, unspecified	0.631	0.369
Q50-Q56 Congenital malformations of genital organs	0.631	0.369
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.630	0.370
E27.1 Primary adrenocortical insufficiency	0.630	0.370
C45 Mesothelioma	0.629	0.371
C81 Hodgkin's disease	0.627	0.373
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.624	0.376
E24.9 Cushing's syndrome, unspecified	0.624	0.376
Chapter V Mental and behavioural disorders	0.622	0.378
E11 Non-insulin-dependent diabetes mellitus	0.622	0.378
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.621	0.379
E14 Unspecified diabetes mellitus	0.620	0.380
C67 Malignant neoplasm of bladder	0.619	0.381
C49.2 Connective and soft tissue of lower limb, including hip	0.616	0.384
R41 Other symptoms and signs involving cognitive functions and awareness	0.613	0.387
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.612	0.387
Q35-Q37 Cleft lip and cleft palate	0.612	0.387
Q30-Q34 Congenital malformations of the respiratory system	0.612	0.387
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.612	0.388
R25.2 Cramp and spasm	0.611	0.389
D80.1 Nonfamilial hypogammaglobulinaemia	0.610	0.390
C79.6 Secondary malignant neoplasm of ovary	0.610	0.390
C25 Malignant neoplasm of pancreas	0.609	0.391
D57 Sickle-cell disorders	0.608	0.392
D56 Thalassaemia	0.608	0.392
D55 Anaemia due to enzyme disorders	0.608	0.392
B15 Acute hepatitis A	0.608	0.392
I95-I99 Other and unspecified disorders of the circulatory system	0.608	0.392
J93.1 Other spontaneous pneumothorax	0.608	0.392
D84.9 Immunodeficiency, unspecified	0.608	0.392
D84.1 Defects in the complement system	0.608	0.392
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.608	0.392
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.607	0.393
C46 Kaposi's sarcoma	0.607	0.393
Q80-Q89 Other congenital malformations	0.605	0.394
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.605	0.394
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.604	0.396
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.604	0.396
I30-I52 Other forms of heart disease	0.603	0.397
C88 Malignant immunoproliferative diseases	0.602	0.397
I70.2 Atherosclerosis of arteries of the extremities	0.602	0.398
C50.0 Nipple and areola	0.602	0.398
C51-C58 Malignant neoplasms of female genital organs	0.602	0.398
B17 Other acute viral hepatitis	0.601	0.399
E66 Obesity	0.601	0.399
D60-D64 Aplastic and other anaemias	0.601	0.399
C79.8 Secondary malignant neoplasm of other specified sites	0.601	0.399
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.600	0.399
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.600	0.399
E13.9 Without complications	0.599	0.401
A40.3 Septicaemia due to Streptococcus pneumoniae	0.598	0.402
B97 Viral agents as the cause of diseases classified to other chapters	0.598	0.402
D58.0 Hereditary spherocytosis	0.598	0.402
C77.8 Lymph nodes of multiple regions	0.597	0.403
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.597	0.403
I72.0 Aneurysm of carotid artery	0.596	0.404
D44.3 Pituitary gland	0.594	0.405
D50 Iron deficiency anaemia	0.594	0.405
I51 Complications and ill-defined descriptions of heart disease	0.594	0.406
A48.1 Legionnaires' disease	0.594	0.406
I74.8 Embolism and thrombosis of other arteries	0.594	0.406
E16 Other disorders of pancreatic internal secretion	0.594	0.406
I77 Other disorders of arteries and arterioles	0.593	0.407
J03 Acute tonsillitis	0.593	0.407
E27.9 Disorder of adrenal gland, unspecified	0.593	0.407
E27.5 Adrenomedullary hyperfunction	0.593	0.407
E27.2 Addisonian crisis	0.593	0.407
E27.0 Other adrenocortical overactivity	0.593	0.407
E12 Malnutrition-related diabetes mellitus	0.593	0.407
I71.8 Aortic aneurysm of unspecified site, ruptured	0.592	0.407
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.592	0.407
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.592	0.407
I71.1 Thoracic aortic aneurysm, ruptured	0.592	0.407
C65 Malignant neoplasm of renal pelvis	0.591	0.409
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.591	0.409
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.591	0.409
I74.0 Embolism and thrombosis of abdominal aorta	0.591	0.409
R41.0 Disorientation, unspecified	0.590	0.410
C66 Malignant neoplasm of ureter	0.589	0.411
Q18 Other congenital malformations of face and neck	0.588	0.412
J98.0 Diseases of bronchus, not elsewhere classified	0.587	0.413
D50.8 Other iron deficiency anaemias	0.586	0.414
J69 Pneumonitis due to solids and liquids	0.585	0.414
J99 Respiratory disorders in diseases classified elsewhere	0.584	0.416
A40.8 Other streptococcal septicaemia	0.584	0.416
A40.2 Septicaemia due to streptococcus, group D	0.584	0.416
A40.1 Septicaemia due to streptococcus, group B	0.584	0.416
A40.0 Septicaemia due to streptococcus, group A	0.584	0.416
C50.8 Overlapping lesion of breast	0.583	0.417
I07 Rheumatic tricuspid valve diseases	0.583	0.417
E27.4 Other and unspecified adrenocortical insufficiency	0.582	0.417
C84 Peripheral and cutaneous T-cell lymphomas	0.581	0.419
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.581	0.419
D43.9 Central nervous system, unspecified	0.581	0.419
D43.7 Other parts of central nervous system	0.581	0.419
D43.4 Spinal cord	0.581	0.419
D43.3 Cranial nerves	0.581	0.419
D43.1 Brain, infratentorial	0.581	0.419
I51.7 Cardiomegaly	0.580	0.420
A87 Viral meningitis	0.580	0.420
C01 Malignant neoplasm of base of tongue	0.579	0.420
J94 Other pleural conditions	0.579	0.421
A60 Anogenital herpesviral [herpes simplex] infections	0.579	0.421
C26.0 Intestinal tract, part unspecified	0.578	0.422
C19 Malignant neoplasm of rectosigmoid junction	0.576	0.424
R44 Other symptoms and signs involving general sensations and perceptions	0.576	0.424
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.576	0.424
D68.2 Hereditary deficiency of other clotting factors	0.576	0.424
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.575	0.425
R26.8 Other and unspecified abnormalities of gait and mobility	0.573	0.427
D45 Polycythaemia vera	0.572	0.428
C79.9 Secondary malignant neoplasm, unspecified site	0.572	0.428
C71 Malignant neoplasm of brain	0.571	0.429
A41.9 Septicaemia, unspecified	0.571	0.429
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.570	0.430
C95 Leukaemia of unspecified cell type	0.570	0.430
C94 Other leukaemias of specified cell type	0.570	0.430
C93 Monocytic leukaemia	0.570	0.430
C86 Other specified types of T/NK-cell lymphoma	0.570	0.430
E10 Insulin-dependent diabetes mellitus	0.570	0.430
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.569	0.431
J84 Other interstitial pulmonary diseases	0.569	0.431
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.569	0.431
C34.0 Main bronchus	0.568	0.431
Chapter VIII Diseases of the ear and mastoid process	0.568	0.432
D68.8 Other specified coagulation defects	0.566	0.434
J00 Acute nasopharyngitis [common cold]	0.566	0.434
B25-B34 Other viral diseases	0.566	0.434
R46 Symptoms and signs involving appearance and behaviour	0.565	0.435
C68 Malignant neoplasm of other and unspecified urinary organs	0.564	0.435
J86 Pyothorax	0.564	0.435
C83 Diffuse non-Hodgkin's lymphoma	0.564	0.436
Q23.1 Congenital insufficiency of aortic valve	0.564	0.436
A86 Unspecified viral encephalitis	0.563	0.436
Chapter VI Diseases of the nervous system	0.563	0.437
Q38-Q45 Other congenital malformations of the digestive system	0.562	0.438
E28.2 Polycystic ovarian syndrome	0.562	0.438
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.560	0.440
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.559	0.440
C67.1 Dome of bladder	0.558	0.442
C49.9 Connective and soft tissue, unspecified	0.558	0.442
D72.9 Disorder of white blood cells, unspecified	0.557	0.443
D72.1 Eosinophilia	0.557	0.443
D72.0 Genetic anomalies of leukocytes	0.557	0.443
Q27 Other congenital malformations of peripheral vascular system	0.556	0.444
C32.9 Larynx, unspecified	0.555	0.445
C90 Multiple myeloma and malignant plasma cell neoplasms	0.555	0.445
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.554	0.446
E11.5 With peripheral circulatory complications	0.553	0.447
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.552	0.448
D80.8 Other immunodeficiencies with predominantly antibody defects	0.552	0.448
D80.7 Transient hypogammaglobulinaemia of infancy	0.552	0.448
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.552	0.448
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.552	0.448
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.552	0.448
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.552	0.448
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.552	0.448
D80.0 Hereditary hypogammaglobulinaemia	0.552	0.448
C44.1 Skin of eyelid, including canthus	0.550	0.450
I70.9 Generalised and unspecified atherosclerosis	0.550	0.450
I70.8 Atherosclerosis of other arteries	0.550	0.450
I70.1 Atherosclerosis of renal artery	0.550	0.450
Q24 Other congenital malformations of heart	0.550	0.450
B19 Unspecified viral hepatitis	0.549	0.451
D37.7 Other digestive organs	0.549	0.451
A19 Miliary tuberculosis	0.549	0.451
A18 Tuberculosis of other organs	0.549	0.451
A17 Tuberculosis of nervous system	0.549	0.451
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.549	0.451
C77.1 Intrathoracic lymph nodes	0.549	0.451
E28.9 Ovarian dysfunction, unspecified	0.549	0.451
E28.8 Other ovarian dysfunction	0.549	0.451
E28.1 Androgen excess	0.549	0.451
E28.0 Oestrogen excess	0.549	0.451
E26.0 Primary hyperaldosteronism	0.547	0.453
I72.3 Aneurysm of iliac artery	0.546	0.453
E11.2 With renal complications	0.546	0.454
C32.1 Supraglottis	0.546	0.454
I11.9 Hypertensive heart disease without (congestive) heart failure	0.546	0.454
E14.3 With ophthalmic complications	0.546	0.454
A88 Other viral infections of central nervous system, not elsewhere classified	0.545	0.455
A85 Other viral encephalitis, not elsewhere classified	0.545	0.455
A84 Tick-borne viral encephalitis	0.545	0.455
A83 Mosquito-borne viral encephalitis	0.545	0.455
A82 Rabies	0.545	0.455
A81 Atypical virus infections of central nervous system	0.545	0.455
A80 Acute poliomyelitis	0.545	0.455
A91 Dengue haemorrhagic fever	0.545	0.455
A90 Dengue fever [classical dengue]	0.545	0.455
A89 Unspecified viral infection of central nervous system	0.545	0.455
C49.1 Connective and soft tissue of upper limb, including shoulder	0.545	0.455
I27.9 Pulmonary heart disease, unspecified	0.544	0.455
A48.8 Other specified bacterial diseases	0.544	0.456
A48.4 Brazilian purpuric fever	0.544	0.456
A48.3 Toxic shock syndrome	0.544	0.456
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.544	0.456
A48.0 Gas gangrene	0.544	0.456
C30.0 Nasal cavity	0.544	0.456
D44.9 Endocrine gland, unspecified	0.544	0.456
D44.8 Pluriglandular involvement	0.544	0.456
D44.7 Aortic body and other paraganglia	0.544	0.456
D44.6 Carotid body	0.544	0.456
D44.5 Pineal gland	0.544	0.456
D44.4 Craniopharyngeal duct	0.544	0.456
D44.2 Parathyroid gland	0.544	0.456

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations