TreeWAS – Variant ID: rs727333

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78.7 Secondary malignant neoplasm of liver	0.000	0.982	0.018
S60.8 Other superficial injuries of wrist and hand	0.008	0.991	0.000
S60 Superficial injury of wrist and hand	0.006	0.994	0.000
Z90.7 Acquired absence of genital organ(s)	0.006	0.994	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.006	0.994	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.005	0.995	0.000
S60.0 Contusion of finger(s) without damage to nail	0.005	0.995	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.004	0.995	0.000
S60.2 Contusion of other parts of wrist and hand	0.004	0.995	0.000
S60.1 Contusion of finger(s) with damage to nail	0.004	0.995	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
M23.3 Other meniscus derangements	0.004	0.996	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.004	0.996	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
K31.7 Polyp of stomach and duodenum	0.000	0.996	0.004
L50.9 Urticaria, unspecified	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.996	0.000
M23.37 Other meniscus derangements-Capsular lig	0.003	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
K22.1 Ulcer of oesophagus	0.000	0.997	0.003
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
J38.1 Polyp of vocal cord and larynx	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.997	0.003
Q61 Cystic kidney disease	0.003	0.997	0.000
K22.5 Diverticulum of oesophagus, acquired	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.000	0.997	0.003
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.997	0.003
K14.8 Other diseases of tongue	0.000	0.997	0.003
K75.4 Autoimmune hepatitis	0.000	0.997	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
K76.6 Portal hypertension	0.000	0.998	0.002
K76.9 Liver disease, unspecified	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.002
K76 Other diseases of liver	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.002
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
K08.3 Retained dental root	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.000	0.998	0.002
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.998	0.002
L50 Urticaria	0.002	0.998	0.000
K70-K77 Diseases of liver	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.002	0.998	0.000
K22.7 Barrett's oesophagus	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
J38.6 Stenosis of larynx	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
K22 Other diseases of oesophagus	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
K76.5 Hepatic veno-occlusive disease	0.000	0.998	0.002
K76.4 Peliosis hepatis	0.000	0.998	0.002
K76.3 Infarction of liver	0.000	0.998	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.998	0.002
K76.1 Chronic passive congestion of liver	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
K70.4 Alcoholic hepatic failure	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
N63 Unspecified lump in breast	0.000	0.998	0.002
K72.1 Chronic hepatic failure	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.000	0.998	0.002
L50.8 Other urticaria	0.002	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.000	0.998	0.002
K70 Alcoholic liver disease	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.001	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.001	0.998	0.000
Q63.2 Ectopic kidney	0.001	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
S66.8 Injury of other muscles and tendons at wrist and hand level	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.998	0.002
K71 Toxic liver disease	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.5 Duplication of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.2 Congenital megaloureter	0.001	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.998	0.000
Q64.4 Malformation of urachus	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.998	0.000
Q64.0 Epispadias	0.001	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.998	0.000
Q73 Reduction defects of unspecified limb	0.001	0.998	0.000
Q72 Reduction defects of lower limb	0.001	0.998	0.000
Q71 Reduction defects of upper limb	0.001	0.998	0.000
Q70 Syndactyly	0.001	0.998	0.000
Q69 Polydactyly	0.001	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.998	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.000	0.998	0.001
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.001	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.001	0.998	0.000
L50.0 Allergic urticaria	0.001	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.001	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.001
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.001
K74.1 Hepatic sclerosis	0.000	0.998	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.001	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.001	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.001	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.001
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.998	0.000
Q79.4 Prune belly syndrome	0.001	0.998	0.000
Q79.3 Gastroschisis	0.001	0.998	0.000
Q79.2 Exomphalos	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.998	0.000
I49.3 Ventricular premature depolarisation	0.001	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.001
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.001
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.001
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.001
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.001
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.001
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.001
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.001
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.001
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.001
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.998	0.001
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
S50.9 Superficial injury of forearm, unspecified	0.001	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q25.1 Coarctation of aorta	0.001	0.999	0.000
S62.7 Multiple fractures of fingers	0.001	0.999	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.999	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Q17 Other congenital malformations of ear	0.001	0.999	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.999	0.000
Q15 Other congenital malformations of eye	0.001	0.999	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.999	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.999	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.999	0.000
A49.0 Staphylococcal infection, unspecified	0.001	0.999	0.000
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
K22.3 Perforation of oesophagus	0.000	0.999	0.001
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.999	0.001
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.999	0.001
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.999	0.001
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Q67.8 Other congenital deformities of chest	0.001	0.999	0.000
Q67.7 Pectus carinatum	0.001	0.999	0.000
Q67.6 Pectus excavatum	0.001	0.999	0.000
Q67.5 Congenital deformity of spine	0.001	0.999	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.999	0.000
Q67.3 Plagiocephaly	0.001	0.999	0.000
Q67.2 Dolichocephaly	0.001	0.999	0.000
Q67.1 Compression facies	0.001	0.999	0.000
Q67.0 Facial asymmetry	0.001	0.999	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.999	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.999	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.999	0.000
Q68.3 Congenital bowing of femur	0.001	0.999	0.000
Q68.2 Congenital deformity of knee	0.001	0.999	0.000
Q68.1 Congenital deformity of hand	0.001	0.999	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.999	0.000
Q69.9 Polydactyly, unspecified	0.001	0.999	0.000
Q69.2 Accessory toe(s)	0.001	0.999	0.000
Q69.1 Accessory thumb(s)	0.001	0.999	0.000
Q69.0 Accessory finger(s)	0.001	0.999	0.000
Q70.9 Syndactyly, unspecified	0.001	0.999	0.000
Q70.4 Polysyndactyly	0.001	0.999	0.000
Q70.3 Webbed toes	0.001	0.999	0.000
Q70.2 Fused toes	0.001	0.999	0.000
Q70.1 Webbed fingers	0.001	0.999	0.000
Q70.0 Fused fingers	0.001	0.999	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.999	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.999	0.000
Q71.6 Lobster-claw hand	0.001	0.999	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.999	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.999	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.999	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.999	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.999	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.999	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.999	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.999	0.000
Q72.7 Split foot	0.001	0.999	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.999	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.999	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.999	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.999	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.999	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.999	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.999	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.999	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.999	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.999	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.999	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.999	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.999	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.999	0.000
Q75.3 Macrocephaly	0.001	0.999	0.000
Q75.2 Hypertelorism	0.001	0.999	0.000
Q75.1 Craniofacial dysostosis	0.001	0.999	0.000
Q75.0 Craniosynostosis	0.001	0.999	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.999	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.999	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.999	0.000
Q77.5 Diastrophic dysplasia	0.001	0.999	0.000
Q77.4 Achondroplasia	0.001	0.999	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.999	0.000
Q77.2 Short rib syndrome	0.001	0.999	0.000
Q77.1 Thanatophoric short stature	0.001	0.999	0.000
Q77.0 Achondrogenesis	0.001	0.999	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.999	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.999	0.000
Q78.6 Multiple congenital exostoses	0.001	0.999	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.999	0.000
Q78.4 Enchondromatosis	0.001	0.999	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.999	0.000
Q78.2 Osteopetrosis	0.001	0.999	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.999	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.999	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.001	0.999	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
Q24 Other congenital malformations of heart	0.001	0.999	0.000
Q80-Q89 Other congenital malformations	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.001	0.999	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.999	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
Q26 Congenital malformations of great veins	0.001	0.999	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.999	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.999	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.999	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.999	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.999	0.000
D46.2 Refractory anaemia with excess of blasts	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.999	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.999	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.999	0.001
Q12.0 Congenital cataract	0.001	0.999	0.000
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
S62.4 Multiple fractures of metacarpal bones	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
F31 Bipolar affective disorder	0.001	0.999	0.000
Q07 Other congenital malformations of nervous system	0.001	0.999	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.001	0.999	0.000
J38.4 Oedema of larynx	0.001	0.999	0.000
K75.0 Abscess of liver	0.000	0.999	0.001
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
S62.1 Fracture of other carpal bone(s)	0.001	0.999	0.000
S65 Injury of blood vessels at wrist and hand level	0.001	0.999	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999	0.000
D39.1 Ovary	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.999	0.001
Q44.6 Cystic disease of liver	0.001	0.999	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.001	0.999	0.000
Q83 Congenital malformations of breast	0.001	0.999	0.000
Q50-Q56 Congenital malformations of genital organs	0.001	0.999	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.001	0.999	0.000
Q12.9 Congenital lens malformation, unspecified	0.001	0.999	0.000
Q12.8 Other congenital lens malformations	0.001	0.999	0.000
Q12.4 Spherophakia	0.001	0.999	0.000
Q12.3 Congenital aphakia	0.001	0.999	0.000
Q12.2 Coloboma of lens	0.001	0.999	0.000
Q12.1 Congenital displaced lens	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
W21.9 Unspecified place	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.999	0.001
M48.02 Spinal stenosis (Cervical region)	0.000	0.999	0.001
K70.1 Alcoholic hepatitis	0.000	0.999	0.001
K74.5 Biliary cirrhosis, unspecified	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.001	0.999	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.999	0.000
Q34 Other congenital malformations of respiratory system	0.001	0.999	0.000
Q33 Congenital malformations of lung	0.001	0.999	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.999	0.000
Q31 Congenital malformations of larynx	0.001	0.999	0.000
Q30 Congenital malformations of nose	0.001	0.999	0.000
Q37 Cleft palate with cleft lip	0.001	0.999	0.000
Q36 Cleft lip	0.001	0.999	0.000
Q35 Cleft palate	0.001	0.999	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.999	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.999	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.999	0.000
Q96 Turner's syndrome	0.001	0.999	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.999	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.999	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.999	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.999	0.000
Q90 Down's syndrome	0.001	0.999	0.000
D48.5 Skin	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.000	0.999	0.001
J32.9 Chronic sinusitis, unspecified	0.000	0.999	0.001
K25.4 Chronic or unspecified with haemorrhage	0.001	0.999	0.000
K70.0 Alcoholic fatty liver	0.000	0.999	0.001
Q83.1 Accessory breast	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
S64.4 Injury of digital nerve of other finger	0.001	0.999	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.001	0.999	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.999	0.000
Q10.7 Congenital malformation of orbit	0.001	0.999	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.001	0.999	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.001	0.999	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.001	0.999	0.000
Q10.3 Other congenital malformations of eyelid	0.001	0.999	0.000
Q10.2 Congenital entropion	0.001	0.999	0.000
Q10.1 Congenital ectropion	0.001	0.999	0.000
Q10.0 Congenital ptosis	0.001	0.999	0.000
Q11.3 Macrophthalmos	0.001	0.999	0.000
Q11.2 Microphthalmos	0.001	0.999	0.000
Q11.1 Other anophthalmos	0.001	0.999	0.000
Q11.0 Cystic eyeball	0.001	0.999	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.001	0.999	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.001	0.999	0.000
Q13.5 Blue sclera	0.001	0.999	0.000
Q13.4 Other congenital corneal malformations	0.001	0.999	0.000
Q13.3 Congenital corneal opacity	0.001	0.999	0.000
Q13.2 Other congenital malformations of iris	0.001	0.999	0.000
Q13.1 Absence of iris	0.001	0.999	0.000
Q13.0 Coloboma of iris	0.001	0.999	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.001	0.999	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q14.3 Congenital malformation of choroid	0.001	0.999	0.000
Q14.2 Congenital malformation of optic disk	0.001	0.999	0.000
Q14.1 Congenital malformation of retina	0.001	0.999	0.000
Q14.0 Congenital malformation of vitreous humour	0.001	0.999	0.000
Q15.9 Congenital malformation of eye, unspecified	0.001	0.999	0.000
Q15.8 Other specified congenital malformations of eye	0.001	0.999	0.000
Q15.0 Congenital glaucoma	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations