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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72819097
log Bayes Factor = 6.00972
Chromosome 2   position 78,461,082  (GRCh37) Explore rs72819097 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M54 Dorsalgia
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
M54.2 Cervicalgia
0.997 0.003 0.000
M54.22 Cervicalgia (Cervical region)
0.995 0.005 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
M54.57 Low back pain (Lumbosacral region)
0.986 0.014 0.000
M35 Other systemic involvement of connective tissue
0.984 0.016 0.000
M54.59 Low back pain (Site unspecified)
0.976 0.024 0.000
M05-M14 Inflammatory polyarthropathies
0.974 0.026 0.000
M54.3 Sciatica
0.971 0.029 0.000
M54.56 Low back pain (Lumbar region)
0.958 0.042 0.000
M06 Other rheumatoid arthritis
0.935 0.065 0.000
M54.39 Sciatica (Site unspecified)
0.916 0.084 0.000
M06.9 Rheumatoid arthritis, unspecified
0.912 0.088 0.000
M35.0 Sicca syndrome [Sjogren]
0.910 0.090 0.000
M54.9 Dorsalgia, unspecified
0.905 0.095 0.000
M05 Seropositive rheumatoid arthritis
0.904 0.096 0.000
M24 Other specific joint derangements
0.900 0.100 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.889 0.111 0.000
M21 Other acquired deformities of limbs
0.889 0.111 0.000
M60-M63 Disorders of muscles
0.882 0.118 0.000
M35.3 Polymyalgia rheumatica
0.882 0.118 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.854 0.146 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.854 0.146 0.000
M00-M03 Infectious arthropathies
0.852 0.147 0.000
M35.7 Hypermobility syndrome
0.852 0.148 0.000
M86-M90 Other osteopathies
0.850 0.150 0.000
M80-M85 Disorders of bone density and structure
0.846 0.154 0.000
M34 Systemic sclerosis
0.843 0.157 0.000
M54.6 Pain in thoracic spine
0.840 0.160 0.000
M54.50 Low back pain (Multiple sites in spine)
0.837 0.163 0.000
M45-M49 Spondylopathies
0.831 0.169 0.000
M54.4 Lumbago with sciatica
0.815 0.184 0.000
M54.54 Low back pain-Thoracic
0.813 0.187 0.000
M12 Other specific arthropathies
0.813 0.187 0.000
M54.36 Sciatica (Lumbar region)
0.812 0.188 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.802 0.198 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.802 0.198 0.000
M22 Disorders of patella
0.800 0.200 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.799 0.201 0.000
M54.37 Sciatica (Lumbosacral region)
0.796 0.204 0.000
M24.1 Other articular cartilage disorders
0.795 0.205 0.000
M21.2 Flexion deformity
0.789 0.211 0.000
M54.8 Other dorsalgia
0.787 0.213 0.000
M54.29 Cervicalgia-Site unspe
0.785 0.215 0.000
M62 Other disorders of muscle
0.783 0.217 0.000
M40-M43 Deforming dorsopathies
0.781 0.219 0.000
M06.4 Inflammatory polyarthropathy
0.781 0.219 0.000
M35.2 Behcet's disease
0.775 0.225 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.774 0.226 0.000
M48 Other spondylopathies
0.773 0.227 0.000
M33 Dermatopolymyositis
0.772 0.228 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.762 0.238 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.757 0.243 0.000
M35.8 Other specified systemic involvement of connective tissue
0.757 0.243 0.000
M31 Other necrotising vasculopathies
0.755 0.245 0.000
M21.6 Other acquired deformities of ankle and foot
0.753 0.247 0.000
M00 Pyogenic arthritis
0.748 0.252 0.000
M11 Other crystal arthropathies
0.745 0.255 0.000
M81 Osteoporosis without pathological fracture
0.742 0.258 0.000
M48.0 Spinal stenosis
0.732 0.268 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.732 0.268 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.726 0.274 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.726 0.274 0.000
M34.8 Other forms of systemic sclerosis
0.724 0.276 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.723 0.277 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M54.53 Low back pain-Cervicothoracic
0.717 0.283 0.000
M54.52 Low back pain-Cervical
0.717 0.283 0.000
M54.51 Low back pain-Occipit-atl-axl
0.717 0.283 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.715 0.285 0.000
M54.27 Cervicalgia-Lumbosacral
0.715 0.285 0.000
M54.26 Cervicalgia-Lumbar
0.715 0.285 0.000
M54.25 Cervicalgia-Thoracolumbar
0.715 0.285 0.000
M54.24 Cervicalgia-Thoracic
0.715 0.285 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.715 0.285 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.715 0.285 0.000
M54.20 Cervicalgia-Mult site
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M88 Paget's disease of bone [osteitis deformans]
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M14 Arthropathies in other diseases classified elsewhere
0.707 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.705 0.294 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.705 0.294 0.000
M35.5 Multifocal fibrosclerosis
0.705 0.294 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.705 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.705 0.295 0.000
M35.1 Other overlap syndromes
0.705 0.295 0.000
M84 Disorders of continuity of bone
0.699 0.301 0.000
M24.5 Contracture of joint
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.698 0.302 0.000
M08 Juvenile arthritis
0.698 0.302 0.000
M48.06 Spinal stenosis (Lumbar region)
0.698 0.302 0.000
M12.3 Palindromic rheumatism
0.697 0.303 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.697 0.303 0.000
M54.35 Sciatica (Thoracolumbar region)
0.696 0.303 0.000
M54.34 Sciatica-Thoracic
0.696 0.303 0.000
M54.33 Sciatica-Cervicothoracic
0.696 0.303 0.000
M54.32 Sciatica-Cervical
0.696 0.303 0.000
M54.31 Sciatica-Occipit-atl-axl
0.696 0.303 0.000
M54.30 Sciatica (Multiple sites in spine)
0.696 0.303 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.692 0.308 0.000
M24.0 Loose body in joint
0.692 0.308 0.000
M34.0 Progressive systemic sclerosis
0.683 0.317 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.680 0.320 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.323 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.676 0.324 0.000
M46 Other inflammatory spondylopathies
0.675 0.325 0.000
M00.9 Pyogenic arthritis, unspecified
0.673 0.327 0.000
M24.2 Disorder of ligament
0.671 0.329 0.000
M06.8 Other specified rheumatoid arthritis
0.670 0.330 0.000
M06.2 Rheumatoid bursitis
0.670 0.330 0.000
M06.1 Adult-onset Still's disease
0.670 0.330 0.000
M90 Osteopathies in diseases classified elsewhere
0.670 0.330 0.000
M60 Myositis
0.670 0.330 0.000
M22.4 Chondromalacia patellae
0.669 0.331 0.000
M43 Other deforming dorsopathies
0.668 0.332 0.000
M21.27 Flexion deformity (Ankle and foot)
0.667 0.333 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.667 0.333 0.000
M24.6 Ankylosis of joint
0.664 0.335 0.000
M81.9 Osteoporosis, unspecified
0.664 0.336 0.000
M22.8 Other disorders of patella
0.663 0.337 0.000
M25 Other joint disorders, not elsewhere classified
0.662 0.338 0.000
M21.7 Unequal limb length (acquired)
0.659 0.341 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.659 0.341 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.656 0.344 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.656 0.344 0.000
M21.3 Wrist or foot drop (acquired)
0.654 0.346 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.653 0.347 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.651 0.349 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.650 0.350 0.000
M94 Other disorders of cartilage
0.650 0.350 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.649 0.351 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.649 0.351 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.649 0.351 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.649 0.351 0.000
M05.8 Other seropositive rheumatoid arthritis
0.648 0.352 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.648 0.352 0.000
M05.2 Rheumatoid vasculitis
0.648 0.352 0.000
M05.1 Rheumatoid lung disease
0.648 0.352 0.000
M05.0 Felty's syndrome
0.648 0.352 0.000
M22.0 Recurrent dislocation of patella
0.645 0.355 0.000
M24.9 Joint derangement, unspecified
0.645 0.355 0.000
M24.7 Protrusio acetabuli
0.645 0.355 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.644 0.356 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.642 0.357 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.642 0.358 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.640 0.360 0.000
M21.9 Acquired deformity of limb, unspecified
0.637 0.363 0.000
M21.8 Other specified acquired deformities of limbs
0.637 0.363 0.000
M89 Other disorders of bone
0.636 0.364 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.636 0.364 0.000
M07 Psoriatic and enteropathic arthropathies
0.635 0.365 0.000
M06.3 Rheumatoid nodule
0.633 0.367 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.632 0.368 0.000
M61 Calcification and ossification of muscle
0.632 0.368 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.627 0.372 0.000
M54.1 Radiculopathy
0.627 0.372 0.000
M62.8 Other specified disorders of muscle
0.627 0.373 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.626 0.374 0.000
M21.0 Valgus deformity, not elsewhere classified
0.626 0.374 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.622 0.378 0.000
M54.86 Other dorsalgia (Lumbar region)
0.621 0.379 0.000
M43.1 Spondylolisthesis
0.619 0.381 0.000
M80 Osteoporosis with pathological fracture
0.619 0.381 0.000
M62.6 Muscle strain
0.618 0.382 0.000
M25.4 Effusion of joint
0.615 0.385 0.000
M87 Osteonecrosis
0.613 0.387 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.613 0.387 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.613 0.387 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.613 0.387 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.613 0.387 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.613 0.387 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.613 0.387 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.613 0.387 0.000
M99 Biomechanical lesions, not elsewhere classified
0.612 0.388 0.000
M88.9 Paget's disease of bone, unspecified
0.612 0.388 0.000
M33.2 Polymyositis
0.612 0.388 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.611 0.389 0.000
M02 Reactive arthropathies
0.611 0.389 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.611 0.389 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.609 0.390 0.000
M83 Adult osteomalacia
0.607 0.393 0.000
M21.26 Flexion deformity (Lower leg)
0.605 0.394 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.605 0.395 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.604 0.395 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.603 0.397 0.000
M54.69 Pain in thoracic spine-Site unspe
0.603 0.397 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.603 0.397 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.603 0.397 0.000
M54.66 Pain in thoracic spine-Lumbar
0.603 0.397 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.603 0.397 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.603 0.397 0.000
M54.62 Pain in thoracic spine-Cervical
0.603 0.397 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.603 0.397 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.603 0.397 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.600 0.400 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.596 0.404 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.591 0.409 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.589 0.411 0.000
M45 Ankylosing spondylitis
0.589 0.411 0.000
M11.8 Other specified crystal arthropathies
0.588 0.412 0.000
M40 Kyphosis and lordosis
0.588 0.412 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.586 0.413 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.585 0.415 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.585 0.415 0.000
M54.44 Lumbago with sciatica-Thoracic
0.585 0.415 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.585 0.415 0.000
M54.42 Lumbago with sciatica-Cervical
0.585 0.415 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.585 0.415 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.585 0.415 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.583 0.417 0.000
M12.5 Traumatic arthropathy
0.583 0.417 0.000
M12.4 Intermittent hydrarthrosis
0.583 0.417 0.000
M12.2 Villonodular synovitis (pigmented)
0.583 0.417 0.000
M12.1 Kaschin-Beck disease
0.583 0.417 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.583 0.417 0.000
M54.89 Other dorsalgia (Site unspecified)
0.582 0.418 0.000
M31.1 Thrombotic microangiopathy
0.581 0.419 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.580 0.420 0.000
M34.1 CR(E)ST syndrome
0.577 0.423 0.000
M21.4 Flat foot [pes planus] (acquired)
0.575 0.425 0.000
M65 Synovitis and tenosynovitis
0.575 0.425 0.000
M22.1 Recurrent subluxation of patella
0.574 0.426 0.000
M22.9 Disorder of patella, unspecified
0.574 0.426 0.000
M89.0 Algoneurodystrophy
0.574 0.426 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.571 0.429 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.570 0.430 0.000
M24.18 Other articular cartilage disorders (Other)
0.570 0.430 0.000
M24.14 Other articular cartilage disorders (Hand)
0.570 0.430 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.570 0.430 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.570 0.430 0.000
M31.9 Necrotising vasculopathy, unspecified
0.570 0.430 0.000
M25.46 Effusion of joint (Lower leg)
0.570 0.430 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.569 0.430 0.000
M86 Osteomyelitis
0.568 0.432 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.568 0.432 0.000
M21.29 Flexion deformity (Site unspecified)
0.566 0.434 0.000
M21.28 Flexion deformity (Other)
0.566 0.434 0.000
M21.23 Flexion deformity (Forearm)
0.566 0.434 0.000
M21.22 Flexion deformity (Upper arm)
0.566 0.434 0.000
M21.21 Flexion deformity (Shoulder region)
0.566 0.434 0.000
M21.20 Flexion deformity (Multiple sites)
0.566 0.434 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.565 0.435 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.565 0.435 0.000
M24.01 Loose body in joint (Shoulder region)
0.565 0.435 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.564 0.436 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.564 0.436 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.564 0.436 0.000
M54.84 Other dorsalgia (Thoracic region)
0.564 0.436 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.564 0.436 0.000
M54.82 Other dorsalgia (Cervical region)
0.564 0.436 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.564 0.436 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.564 0.436 0.000
M21.1 Varus deformity, not elsewhere classified
0.564 0.436 0.000
M62.9 Disorder of muscle, unspecified
0.562 0.438 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.562 0.438 0.000
M62.4 Contracture of muscle
0.562 0.438 0.000
M62.3 Immobility syndrome (paraplegic)
0.562 0.438 0.000
M62.2 Ischaemic infarction of muscle
0.562 0.438 0.000
M62.0 Diastasis of muscle
0.562 0.438 0.000
M42 Spinal osteochondrosis
0.560 0.440 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.560 0.440 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.560 0.440 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.560 0.440 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.560 0.440 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.560 0.440 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.560 0.440 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.560 0.440 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.560 0.440 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.560 0.440 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.559 0.441 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.558 0.442 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.555 0.445 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.555 0.445 0.000
M96.5 Postradiation scoliosis
0.555 0.445 0.000
M96.4 Postsurgical lordosis
0.555 0.445 0.000
M96.3 Postlaminectomy kyphosis
0.555 0.445 0.000
M96.2 Postradiation kyphosis
0.555 0.445 0.000
M54.55 Low back pain (Thoracolumbar region)
0.555 0.445 0.000
M48.9 Spondylopathy, unspecified
0.554 0.446 0.000
M48.8 Other specified spondylopathies
0.554 0.446 0.000
M48.4 Fatigue fracture of vertebra
0.554 0.446 0.000
M48.3 Traumatic spondylopathy
0.554 0.446 0.000
M48.2 Kissing spine
0.554 0.446 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.554 0.446 0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)
0.554 0.446 0.000
M33.9 Dermatopolymyositis, unspecified
0.553 0.447 0.000
M33.1 Other dermatomyositis
0.553 0.447 0.000
M33.0 Juvenile dermatomyositis
0.553 0.447 0.000
M84.4 Pathological fracture, not elsewhere classified
0.552 0.447 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.552 0.448 0.000
M34.9 Systemic sclerosis, unspecified
0.552 0.448 0.000
M82 Osteoporosis in diseases classified elsewhere
0.551 0.448 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.551 0.449 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.550 0.449 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.550 0.450 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.550 0.450 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.550 0.450 0.000
M81.4 Drug-induced osteoporosis
0.547 0.453 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.544 0.455 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.543 0.457 0.000
M25.5 Pain in joint
0.542 0.458 0.000
M31.8 Other specified necrotising vasculopathies
0.541 0.459 0.000
M31.7 Microscopic polyangiitis
0.541 0.459 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.541 0.459 0.000
M31.2 Lethal midline granuloma
0.541 0.459 0.000
M31.0 Hypersensitivity angiitis
0.541 0.459 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.541 0.459 0.000
M90.7 Fracture of bone in neoplastic disease
0.541 0.459 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.540 0.460 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.540 0.460 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.540 0.460 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.540 0.460 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.540 0.460 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.540 0.460 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.540 0.460 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.540 0.460 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.540 0.460 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.539 0.461 0.000
M94.2 Chondromalacia
0.539 0.461 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.536 0.464 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.536 0.464 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.536 0.464 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.536 0.464 0.000
M60.0 Infective myositis
0.536 0.464 0.000
M31.6 Other giant cell arteritis
0.536 0.464 0.000
M49 Spondylopathies in diseases classified elsewhere
0.535 0.465 0.000
M11.9 Crystal arthropathy, unspecified
0.534 0.465 0.000
M11.1 Familial chondrocalcinosis
0.534 0.465 0.000
M11.0 Hydroxyapatite deposition disease
0.534 0.465 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.533 0.467 0.000
M81.8 Other osteoporosis
0.532 0.468 0.000
M81.6 Localised osteoporosis [Lequesne]
0.532 0.468 0.000
M81.5 Idiopathic osteoporosis
0.532 0.468 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.532 0.468 0.000
M81.1 Postoophorectomy osteoporosis
0.532 0.468 0.000
M81.0 Postmenopausal osteoporosis
0.532 0.468 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.530 0.470 0.000
M46.4 Discitis, unspecified
0.530 0.470 0.000
M21.24 Flexion deformity (Hand)
0.528 0.472 0.000
M25.52 Pain in joint (Upper arm)
0.527 0.473 0.000
M11.2 Other chondrocalcinosis
0.526 0.474 0.000
M24.07 Loose body in joint (Ankle and foot)
0.525 0.474 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.525 0.475 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.525 0.475 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.525 0.475 0.000
M81.2 Osteoporosis of disuse
0.523 0.477 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.521 0.479 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.521 0.479 0.000
M24.26 Disorder of ligament (Lower leg)
0.520 0.480 0.000
M23 Internal derangement of knee
0.517 0.483 0.000
M93 Other osteochondropathies
0.517 0.483 0.000
M14.6 Neuropathic arthropathy
0.517 0.483 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.516 0.484 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.514 0.486 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.514 0.486 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.514 0.486 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.514 0.486 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.514 0.486 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.514 0.486 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.514 0.486 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.514 0.486 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.514 0.486 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.514 0.486 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.513 0.487 0.000
M54.19 Radiculopathy (Site unspecified)
0.512 0.488 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.511 0.488 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.511 0.488 0.000
M36.3 Arthropathy in other blood disorders
0.511 0.488 0.000
M36.2 Haemophilic arthropathy
0.511 0.488 0.000
M36.1 Arthropathy in neoplastic disease
0.511 0.488 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.511 0.488 0.000
M88.8 Paget's disease of other bones
0.510 0.490 0.000
M88.0 Paget's disease of skull
0.510 0.490 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.510 0.490 0.000
M24.57 Contracture of joint (Ankle and foot)
0.508 0.492 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.508 0.492 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.508 0.492 0.000
M32.8 Other forms of systemic lupus erythematosus
0.508 0.492 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.508 0.492 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.507 0.493 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.507 0.493 0.000
M14.4 Arthropathy in amyloidosis
0.507 0.493 0.000
M14.3 Lipoid dermatoarthritis
0.507 0.493 0.000
M14.2 Diabetic arthropathy
0.507 0.493 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.507 0.493 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.507 0.493 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.507 0.493 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.507 0.493 0.000
M30.2 Juvenile polyarteritis
0.507 0.493 0.000
M30.0 Polyarteritis nodosa
0.507 0.493 0.000
M31.3 Wegener's granulomatosis
0.507 0.493 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.506 0.494 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.506 0.494 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.505 0.495 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.503 0.497 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.503 0.497 0.000
M24.23 Disorder of ligament (Forearm)
0.502 0.498 0.000
M62.88 Other specified disorders of muscle (Other)
0.502 0.498 0.000
M84.9 Disorder of continuity of bone, unspecified
0.501 0.498 0.000
M84.8 Other disorders of continuity of bone
0.501 0.498 0.000
M84.3 Stress fracture, not elsewhere classified
0.501 0.498 0.000
M84.2 Delayed union of fracture
0.501 0.498 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.501 0.499 0.000
M24.51 Contracture of joint (Shoulder region)
0.501 0.499 0.000
M24.59 Contracture of joint (Site unspecified)
0.501 0.499 0.000
M24.58 Contracture of joint (Other)
0.501 0.499 0.000
M24.56 Contracture of joint (Lower leg)
0.501 0.499 0.000
M24.53 Contracture of joint (Forearm)
0.501 0.499 0.000
M24.52 Contracture of joint (Upper arm)
0.501 0.499 0.000
M24.50 Contracture of joint (Multiple sites)
0.501 0.499 0.000
M08.9 Juvenile arthritis, unspecified
0.500 0.499 0.000
M08.8 Other juvenile arthritis
0.500 0.499 0.000
M08.4 Pauciarticular juvenile arthritis
0.500 0.499 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.500 0.499 0.000
M08.2 Juvenile arthritis with systemic onset
0.500 0.499 0.000
M08.1 Juvenile ankylosing spondylitis
0.500 0.499 0.000
M08.0 Juvenile rheumatoid arthritis
0.500 0.499 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.500 0.499 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.500 0.499 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.500 0.499 0.000
M09.0 Juvenile arthritis in psoriasis
0.500 0.499 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.500 0.499 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.500 0.500 0.000
M94.8 Other specified disorders of cartilage
0.500 0.500 0.000
M12.38 Palindromic rheumatism (Other)
0.500 0.500 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.500 0.500 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.500 0.500 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.500 0.500 0.000
M12.34 Palindromic rheumatism (Hand)
0.500 0.500 0.000
M12.33 Palindromic rheumatism (Forearm)
0.500 0.500 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.500 0.500 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.500 0.500 0.000
M85 Other disorders of bone density and structure
0.499 0.501 0.000
M48.04 Spinal stenosis (Thoracic region)
0.499 0.501 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.497 0.503 0.000
M24.54 Contracture of joint (Hand)
0.497 0.503 0.000
M24.09 Loose body in joint (Site unspecified)
0.496 0.504 0.000
M24.08 Loose body in joint (Other)
0.496 0.504 0.000
M24.06 Loose body in joint-Lower leg
0.496 0.504 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.496 0.504 0.000
M24.04 Loose body in joint (Hand)
0.496 0.504 0.000
M24.03 Loose body in joint (Forearm)
0.496 0.504 0.000
M24.00 Loose body in joint (Multiple sites)
0.496 0.504 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.496 0.504 0.000
M54.16 Radiculopathy (Lumbar region)
0.495 0.505 0.000
M51 Other intervertebral disk disorders
0.494 0.506 0.000
M21.76 Unequal limb length (acquired) (Lower leg)
0.494 0.506 0.000
M22.3 Other derangements of patella
0.493 0.506 0.000
M10 Gout
0.492 0.508 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.490 0.510 0.000
M94.9 Disorder of cartilage, unspecified
0.489 0.511 0.000
M62.66 Muscle strain (Lower leg)
0.488 0.512 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.488 0.512 0.000
M25.0 Haemarthrosis
0.487 0.512 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.487 0.513 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.486 0.514 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.486 0.514 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.486 0.514 0.000
M53.9 Dorsopathy, unspecified
0.485 0.514 0.000
M53.8 Other specified dorsopathies
0.485 0.514 0.000
M53.2 Spinal instabilities
0.485 0.514 0.000
M53.1 Cervicobrachial syndrome
0.485 0.514 0.000
M53.0 Cervicocranial syndrome
0.485 0.514 0.000
M24.24 Disorder of ligament (Hand)
0.485 0.515 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.484 0.516 0.000
M46.8 Other specified inflammatory spondylopathies
0.484 0.516 0.000
M46.5 Other infective spondylopathies
0.484 0.516 0.000
M46.2 Osteomyelitis of vertebra
0.484 0.516 0.000
M46.0 Spinal enthesopathy
0.484 0.516 0.000
M87.9 Osteonecrosis, unspecified
0.484 0.516 0.000
M24.21 Disorder of ligament (Shoulder region)
0.483 0.517 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.482 0.517 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.482 0.517 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.482 0.517 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.482 0.517 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.482 0.517 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.482 0.517 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.482 0.517 0.000
M24.29 Disorder of ligament (Site unspecified)
0.481 0.519 0.000
M24.28 Disorder of ligament (Other)
0.481 0.519 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.481 0.519 0.000
M24.22 Disorder of ligament (Upper arm)
0.481 0.519 0.000
M24.20 Disorder of ligament (Multiple sites)
0.481 0.519 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.480 0.519 0.000
M06.18 Adult-onset Still's disease (Other)
0.480 0.519 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.480 0.519 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.480 0.519 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.480 0.519 0.000
M06.14 Adult-onset Still's disease (Hand)
0.480 0.519 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.480 0.519 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.480 0.519 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.480 0.519 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.480 0.519 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.480 0.519 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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