TreeWAS – Variant ID: rs72923818

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.1 Crohn's disease of large intestine	0.000	0.966	0.034
K50 Crohn's disease [regional enteritis]	0.000	0.966	0.034
K50.9 Crohn's disease, unspecified	0.000	0.966	0.034
K50.0 Crohn's disease of small intestine	0.000	0.968	0.032
D12.0 Caecum	0.031	0.969	0.000
K50.8 Other Crohn's disease	0.000	0.972	0.028
Z02.8 Other examinations for administrative purposes	0.000	0.990	0.010
Y42.5 Other oestrogens and progestogens	0.008	0.992	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.993	0.007
F45.8 Other somatoform disorders	0.007	0.993	0.000
D86.0 Sarcoidosis of lung	0.006	0.994	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.994	0.000
D86 Sarcoidosis	0.005	0.995	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
F45 Somatoform disorders	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
L40.5 Arthropathic psoriasis	0.004	0.996	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
M23.8 Other internal derangements of knee	0.000	0.996	0.004
M48.06 Spinal stenosis (Lumbar region)	0.000	0.996	0.004
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.996	0.004
L40.9 Psoriasis, unspecified	0.004	0.996	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.004	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.004	0.996	0.000
L40 Psoriasis	0.004	0.996	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.996	0.004
F31 Bipolar affective disorder	0.004	0.996	0.000
F45.9 Somatoform disorder, unspecified	0.004	0.996	0.000
F45.4 Persistent somatoform pain disorder	0.004	0.996	0.000
F45.3 Somatoform autonomic dysfunction	0.004	0.996	0.000
F45.2 Hypochondriacal disorder	0.004	0.996	0.000
F45.1 Undifferentiated somatoform disorder	0.004	0.996	0.000
F45.0 Somatisation disorder	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
F43 Reaction to severe stress, and adjustment disorders	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.003
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
R33 Retention of urine	0.000	0.997	0.003
F40-F48 Neurotic, stress-related and somatoform disorders	0.003	0.997	0.000
M48.0 Spinal stenosis	0.000	0.997	0.003
Z02.9 Examination for administrative purposes, unspecified	0.000	0.997	0.003
Z02.7 Issue of medical certificate	0.000	0.997	0.003
Z02.6 Examination for insurance purposes	0.000	0.997	0.003
Z02.5 Examination for participation in sport	0.000	0.997	0.003
Z02.4 Examination for driving licence	0.000	0.997	0.003
Z02.3 Examination for recruitment to armed forces	0.000	0.997	0.003
Z02.2 Examination for admission to residential institution	0.000	0.997	0.003
Z02.1 Pre-employment examination	0.000	0.997	0.003
Z02.0 Examination for admission to educational institution	0.000	0.997	0.003
F43.2 Adjustment disorders	0.003	0.997	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
R00.0 Tachycardia, unspecified	0.000	0.997	0.003
L40.0 Psoriasis vulgaris	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.000	0.997	0.003
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
L40.8 Other psoriasis	0.003	0.997	0.000
L40.4 Guttate psoriasis	0.003	0.997	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.997	0.000
L40.2 Acrodermatitis continua	0.003	0.997	0.000
L40.1 Generalised pustular psoriasis	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.997	0.003
M48.09 Spinal stenosis (Site unspecified)	0.000	0.997	0.003
F30 Manic episode	0.003	0.997	0.000
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
F43.0 Acute stress reaction	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
F44 Dissociative [conversion] disorders	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
F43.9 Reaction to severe stress, unspecified	0.003	0.997	0.000
F43.8 Other reactions to severe stress	0.003	0.997	0.000
F30.0 Hypomania	0.003	0.997	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.003	0.997	0.000
F40 Phobic anxiety disorders	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.997	0.003
M48.04 Spinal stenosis (Thoracic region)	0.000	0.997	0.003
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.997	0.003
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.997	0.003
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.997	0.003
F48 Other neurotic disorders	0.003	0.997	0.000
F42 Obsessive-compulsive disorder	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
F34 Persistent mood [affective] disorders	0.003	0.997	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.997	0.003
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.003	0.997	0.000
F30.2 Mania with psychotic symptoms	0.002	0.997	0.000
F44.4 Dissociative motor disorders	0.002	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.997	0.003
H33.2 Serous retinal detachment	0.003	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.997	0.003
O16 Unspecified maternal hypertension	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.002	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.002
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.002	0.998	0.000
F34.1 Dysthymia	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.002	0.998	0.000
F44.8 Other dissociative [conversion] disorders	0.002	0.998	0.000
F44.7 Mixed dissociative [conversion] disorders	0.002	0.998	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.002	0.998	0.000
F44.5 Dissociative convulsions	0.002	0.998	0.000
F44.3 Trance and possession disorders	0.002	0.998	0.000
F44.2 Dissociative stupor	0.002	0.998	0.000
F44.1 Dissociative fugue	0.002	0.998	0.000
F44.0 Dissociative amnesia	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
F40.0 Agoraphobia	0.002	0.998	0.000
J98.1 Pulmonary collapse	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Z13.9 Special screening examination, unspecified	0.000	0.998	0.002
Z30.2 Sterilisation	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
F42.8 Other obsessive-compulsive disorders	0.002	0.998	0.000
F42.2 Mixed obsessional thoughts and acts	0.002	0.998	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.002	0.998	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
F48.9 Neurotic disorder, unspecified	0.002	0.998	0.000
F48.8 Other specified neurotic disorders	0.002	0.998	0.000
F48.1 Depersonalisation-derealisation syndrome	0.002	0.998	0.000
F48.0 Neurasthenia	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.002	0.998	0.000
S42.1 Fracture of scapula	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.000	0.998	0.002
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
D17 Benign lipomatous neoplasm	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.002
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
S42.4 Fracture of lower end of humerus	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
J98 Other respiratory disorders	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.002	0.998	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.998	0.002
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.000	0.998	0.002
E11.4 With neurological complications	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Z93.2 Ileostomy status	0.000	0.998	0.002
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.998	0.002
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
D17.7 Benign lipomatous neoplasm of other sites	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
M48 Other spondylopathies	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
Y43 Primarily systemic agents	0.002	0.998	0.000
Chapter V Mental and behavioural disorders	0.002	0.998	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.002	0.998	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
N25 Disorders resulting from impaired renal tubular function	0.002	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
K08 Other disorders of teeth and supporting structures	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
N27.0 Small kidney, unilateral	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.001
I84.1 Internal haemorrhoids with other complications	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.001	0.998	0.000
N25-N29 Other disorders of kidney and ureter	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.001
J98.6 Disorders of diaphragm	0.000	0.998	0.001
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.998	0.001
J98.3 Compensatory emphysema	0.000	0.998	0.001
J98.2 Interstitial emphysema	0.000	0.998	0.001
K10.2 Inflammatory conditions of jaws	0.002	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.998	0.000
N27 Small kidney of unknown cause	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.001	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.001	0.998	0.000
F60.9 Personality disorder, unspecified	0.001	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.998	0.000
Q51.2 Other doubling of uterus	0.001	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.000
Y40 Systemic antibiotics	0.001	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.001	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
F60 Specific personality disorders	0.001	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.001
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.998	0.001
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.998	0.001
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.998	0.001
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.998	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.001	0.998	0.000
Q66 Congenital deformities of feet	0.001	0.998	0.000
F99-F99 Unspecified mental disorder	0.001	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.001
M48.9 Spondylopathy, unspecified	0.000	0.998	0.001
M48.8 Other specified spondylopathies	0.000	0.998	0.001
M48.4 Fatigue fracture of vertebra	0.000	0.998	0.001
M48.3 Traumatic spondylopathy	0.000	0.998	0.001
M48.2 Kissing spine	0.000	0.998	0.001
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.998	0.001
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.001
K10 Other diseases of jaws	0.001	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.001	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.001	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.001	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.001	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.001	0.998	0.000
Y43.2 Antineoplastic natural products	0.001	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.001	0.998	0.000
Y45.1 Salicylates	0.001	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
Q54 Hypospadias	0.001	0.998	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.998	0.000
F70-F79 Mental retardation	0.001	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.998	0.001
I42.9 Cardiomyopathy, unspecified	0.001	0.998	0.000
Q26 Congenital malformations of great veins	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.001	0.998	0.000
Q24 Other congenital malformations of heart	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.001	0.999	0.000
N25.1 Nephrogenic diabetes insipidus	0.001	0.999	0.000
N25.0 Renal osteodystrophy	0.001	0.999	0.000
Y44.2 Anticoagulants	0.001	0.999	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.999	0.001
F80-F89 Disorders of psychological development	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations