TreeWAS – Variant ID: rs730566

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R59.1 Generalised enlarged lymph nodes	0.000	0.980	0.020
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.016	0.984	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.015	0.985	0.000
M18 Arthrosis of first carpometacarpal joint	0.015	0.985	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.013	0.987	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.012	0.988	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.012	0.988	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.011	0.989	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.011	0.989	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.011	0.989	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.011	0.989	0.000
T91 Sequelae of injuries of neck and trunk	0.009	0.991	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.009	0.991	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.991	0.009
F32.1 Moderate depressive episode	0.009	0.991	0.000
M45 Ankylosing spondylitis	0.008	0.992	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.992	0.008
T91.3 Sequelae of injury of spinal cord	0.008	0.992	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.007	0.993	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.007	0.993	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.007	0.993	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.007	0.993	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.007	0.993	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.007	0.993	0.000
H47.3 Other disorders of optic disk	0.007	0.993	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.994	0.006
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.006	0.994	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.006	0.994	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.006	0.994	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.006	0.994	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.006	0.994	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.006	0.994	0.000
H72.0 Central perforation of tympanic membrane	0.006	0.994	0.000
H69.8 Other specified disorders of Eustachian tube	0.005	0.994	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.005	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
H71 Cholesteatoma of middle ear	0.005	0.995	0.000
C67.6 Ureteric orifice	0.000	0.995	0.005
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
M67.0 Short Achilles tendon (acquired)	0.005	0.995	0.000
C67.2 Lateral wall of bladder	0.000	0.995	0.005
H69 Other disorders of Eustachian tube	0.005	0.995	0.000
M84.0 Malunion of fracture	0.005	0.995	0.000
M67 Other disorders of synovium and tendon	0.005	0.995	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.995	0.005
M84 Disorders of continuity of bone	0.005	0.995	0.000
D32.0 Cerebral meninges	0.005	0.995	0.000
C50.3 Lower-inner quadrant of breast	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.004	0.995	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
T91.1 Sequelae of fracture of spine	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
M84.4 Pathological fracture, not elsewhere classified	0.004	0.996	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
M84.04 Malunion of fracture (Hand)	0.004	0.996	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
M67.4 Ganglion	0.004	0.996	0.000
K35.3 Acute appendicitis with localized peritonitis	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
M84.02 Malunion of fracture (Upper arm)	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.004	0.996	0.000
C67.1 Dome of bladder	0.000	0.996	0.004
D32.9 Meninges, unspecified	0.004	0.996	0.000
M84.03 Malunion of fracture (Forearm)	0.004	0.996	0.000
M84.06 Malunion of fracture (Lower leg)	0.004	0.996	0.000
J38.7 Other diseases of larynx	0.004	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
M67.1 Other contracture of tendon (sheath)	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.004	0.996	0.000
M66 Spontaneous rupture of synovium and tendon	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.004	0.996	0.000
D32 Benign neoplasm of meninges	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.000	0.996	0.004
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.004	0.996	0.000
M66.0 Rupture of popliteal cyst	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.004	0.996	0.000
M67.43 Ganglion, wrist	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.004	0.996	0.000
M84.08 Malunion of fracture (Other)	0.004	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.004	0.996	0.000
C67.8 Overlapping lesion of bladder	0.000	0.996	0.004
C67.5 Bladder neck	0.000	0.996	0.004
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.996	0.000
M67.3 Transient synovitis	0.004	0.996	0.000
M84.01 Malunion of fracture (Shoulder region)	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
M84.9 Disorder of continuity of bone, unspecified	0.003	0.996	0.000
M84.3 Stress fracture, not elsewhere classified	0.003	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.996	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.996	0.000
M84.8 Other disorders of continuity of bone	0.003	0.996	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.003	0.996	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.996	0.003
D32.1 Spinal meninges	0.003	0.996	0.000
M66.3 Spontaneous rupture of flexor tendons	0.003	0.996	0.000
M65-M68 Disorders of synovium and tendon	0.003	0.996	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.003
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
C67.7 Urachus	0.000	0.997	0.003
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.003	0.997	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
M96.5 Postradiation scoliosis	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.003	0.997	0.000
M67.45 Ganglion, hip	0.003	0.997	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.003	0.997	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
C67.0 Trigone of bladder	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
W13.9 Unspecified place	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.003	0.997	0.000
M66.1 Rupture of synovium	0.003	0.997	0.000
J36 Peritonsillar abscess	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
C07 Malignant neoplasm of parotid gland	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
M66.2 Spontaneous rupture of extensor tendons	0.003	0.997	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.003	0.997	0.000
M66.08 Rupture of popliteal cyst-Other	0.003	0.997	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.003	0.997	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.003	0.997	0.000
M66.04 Rupture of popliteal cyst-Hand	0.003	0.997	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.003	0.997	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.003	0.997	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.003	0.997	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.003	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.003	0.997	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.003	0.997	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.997	0.000
C78.0 Secondary malignant neoplasm of lung	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.003	0.997	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.003	0.997	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.003	0.997	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.003	0.997	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.003	0.997	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.003	0.997	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.003	0.997	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.003	0.997	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.003	0.997	0.000
M84.88 Other disorders of continuity of bone (Other)	0.003	0.997	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.003	0.997	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.003	0.997	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.003	0.997	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.003	0.997	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.003	0.997	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.003	0.997	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.003	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.003	0.997	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.003	0.997	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.003	0.997	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.003	0.997	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.003	0.997	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.003	0.997	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.003	0.997	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.003	0.997	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.003	0.997	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.003	0.997	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.003	0.997	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.003	0.997	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.003	0.997	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.003	0.997	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.003	0.997	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.003	0.997	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.003	0.997	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.003	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.997	0.003
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.997	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.997	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.997	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.997	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.997	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.997	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.997	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.997	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
G54.0 Brachial plexus disorders	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.997	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.003	0.997	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.997	0.000
L03.0 Cellulitis of finger and toe	0.000	0.997	0.003
M83.1 Senile osteomalacia	0.002	0.997	0.000
H66.0 Acute suppurative otitis media	0.002	0.997	0.000
M62.6 Muscle strain	0.002	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
M62 Other disorders of muscle	0.002	0.997	0.000
M66.19 Rupture of synovium (Site unspecified)	0.002	0.998	0.000
M66.18 Rupture of synovium (Other)	0.002	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.002	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.002	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.002	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.002	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.002	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.002	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.002	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.002	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.002	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.002	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.002	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.002	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.002	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.002	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.002	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.002	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.002	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
E27.2 Addisonian crisis	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M94.2 Chondromalacia	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
M83.12 Senile osteomalacia (Upper arm)	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
M91-M94 Chondropathies	0.002	0.998	0.000
M60-M63 Disorders of muscles	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
K01.1 Impacted teeth	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
M45-M49 Spondylopathies	0.002	0.998	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.002	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.002	0.998	0.000
M62.68 Muscle strain (Other)	0.002	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
M62.64 Muscle strain (Hand)	0.002	0.998	0.000
M62.63 Muscle strain (Forearm)	0.002	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.002	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.002	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.002	0.998	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.002	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.002	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.002	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.002	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.002	0.998	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M92 Other juvenile osteochondrosis	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.002	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.002	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.002	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.002	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations