TreeWAS – Variant ID: rs73069924

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.0 Aortic (valve) stenosis	0.000	0.968	0.032
Z95.4 Presence of other heart-valve replacement	0.000	0.972	0.028
I35 Nonrheumatic aortic valve disorders	0.000	0.980	0.020
Z86.7 Personal history of diseases of the circulatory system	0.000	0.980	0.020
Z86.4 Personal history of psychoactive substance abuse	0.000	0.980	0.020
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.981	0.019
Z86 Personal history of certain other diseases	0.000	0.981	0.019
Z95.2 Presence of prosthetic heart valve	0.000	0.982	0.018
Z86.6 Personal history of diseases of the nervous system and sense organs	0.000	0.982	0.018
I35.9 Aortic valve disorder, unspecified	0.000	0.983	0.017
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.983	0.017
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.984	0.016
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.984	0.016
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.984	0.016
I35.1 Aortic (valve) insufficiency	0.000	0.985	0.015
Z95.1 Presence of aortocoronary bypass graft	0.000	0.985	0.015
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.985	0.015
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.986	0.014
I35.8 Other aortic valve disorders	0.000	0.986	0.014
Z95.3 Presence of xenogenic heart valve	0.000	0.986	0.014
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.989	0.011
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.990	0.009
H35.8 Other specified retinal disorders	0.009	0.991	0.000
Z86.0 Personal history of other neoplasms	0.000	0.991	0.009
H35 Other retinal disorders	0.008	0.992	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
H35.0 Background retinopathy and retinal vascular changes	0.008	0.992	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
H35.3 Degeneration of macula and posterior pole	0.007	0.993	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.007	0.993	0.000
H35.2 Other proliferative retinopathy	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.994	0.006
H35.9 Retinal disorder, unspecified	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
H35.7 Separation of retinal layers	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
H35.5 Hereditary retinal dystrophy	0.006	0.994	0.000
H35.1 Retinopathy of prematurity	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
H35.6 Retinal haemorrhage	0.006	0.994	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
T43.9 Psychotropic drug, unspecified	0.006	0.994	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T43.2 Other and unspecified antidepressants	0.005	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
H35.4 Peripheral retinal degeneration	0.005	0.995	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.995	0.005
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.995	0.000
T39.2 Pyrazolone derivatives	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
T42.4 Benzodiazepines	0.005	0.995	0.000
H30-H36 Disorders of choroid and retina	0.005	0.995	0.000
T39.0 Salicylates	0.004	0.995	0.000
T40.2 Other opioids	0.004	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
H33.2 Serous retinal detachment	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.3 Macrolides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.004	0.996	0.000
H34 Retinal vascular occlusions	0.004	0.996	0.000
R22.1 Localised swelling, mass and lump, neck	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
H33 Retinal detachments and breaks	0.004	0.996	0.000
R22.2 Localised swelling, mass and lump, trunk	0.004	0.996	0.000
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.003	0.996	0.000
H31 Other disorders of choroid	0.003	0.996	0.000
H30 Chorioretinal inflammation	0.003	0.996	0.000
H34.2 Other retinal artery occlusions	0.003	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.003	0.997	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.003	0.997	0.000
H34.9 Retinal vascular occlusion, unspecified	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
H34.0 Transient retinal artery occlusion	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
H33.4 Traction detachment of retina	0.003	0.997	0.000
H33.1 Retinoschisis and retinal cysts	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
S83.2 Tear of meniscus, current	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.997	0.000
H30.8 Other chorioretinal inflammations	0.003	0.997	0.000
H30.2 Posterior cyclitis	0.003	0.997	0.000
H30.1 Disseminated chorioretinal inflammation	0.003	0.997	0.000
H30.0 Focal chorioretinal inflammation	0.003	0.997	0.000
H31.9 Disorder of choroid, unspecified	0.003	0.997	0.000
H31.8 Other specified disorders of choroid	0.003	0.997	0.000
H31.4 Choroidal detachment	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
H31.2 Hereditary choroidal dystrophy	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.003	0.997	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H33.5 Other retinal detachments	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
H33.0 Retinal detachment with retinal break	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.003	0.997	0.000
M20.1 Hallux valgus (acquired)	0.000	0.997	0.003
S89.8 Other specified injuries of lower leg	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
R23 Other skin changes	0.003	0.997	0.000
S81 Open wound of lower leg	0.003	0.997	0.000
R20.2 Paraesthesia of skin	0.003	0.997	0.000
T92 Sequelae of injuries of upper limb	0.002	0.997	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.997	0.000
S81.0 Open wound of knee	0.002	0.997	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
D18.0 Haemangioma, any site	0.000	0.998	0.002
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
N30.2 Other chronic cystitis	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
L30 Other dermatitis	0.002	0.998	0.000
M20 Acquired deformities of fingers and toes	0.000	0.998	0.002
A09.9 Gastroenteritis and colitis of unspecified origin	0.002	0.998	0.000
R20 Disturbances of skin sensation	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
R23.2 Flushing	0.002	0.998	0.000
R23.0 Cyanosis	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.998	0.002
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.002	0.998	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.002	0.998	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.002	0.998	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.002	0.998	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.002	0.998	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.002	0.998	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.002	0.998	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.002	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.002	0.998	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.998	0.002
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.002	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
M20.2 Hallux rigidus	0.000	0.998	0.002
R04.2 Haemoptysis	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
S40 Superficial injury of shoulder and upper arm	0.002	0.998	0.000
T11 Other injuries of upper limb, level unspecified	0.002	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.998	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.998	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.998	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.998	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.998	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.998	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.998	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.998	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.002	0.998	0.000
T08 Fracture of spine, level unspecified	0.002	0.998	0.000
L30.5 Pityriasis alba	0.002	0.998	0.000
L30.4 Erythema intertrigo	0.002	0.998	0.000
L30.3 Infective dermatitis	0.002	0.998	0.000
L30.2 Cutaneous autosensitisation	0.002	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.002	0.998	0.000
R20.1 Hypoaesthesia of skin	0.002	0.998	0.000
R20.0 Anaesthesia of skin	0.002	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
T33-T35 Frostbite	0.002	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.002	0.998	0.000
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.002	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
N30.0 Acute cystitis	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.001	0.998	0.000
S17 Crushing injury of neck	0.001	0.998	0.000
S15 Injury of blood vessels at neck level	0.001	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.998	0.000
S11 Open wound of neck	0.001	0.998	0.000
S10 Superficial injury of neck	0.001	0.998	0.000
S18 Traumatic amputation at neck level	0.001	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.001	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.002	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S44 Injury of nerves at shoulder and upper arm level	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.001	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.998	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.998	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.001	0.998	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.001	0.998	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.001	0.998	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.001	0.998	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.001	0.998	0.000
T09.3 Injury of spinal cord, level unspecified	0.001	0.998	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.001	0.998	0.000
T09.1 Open wound of trunk, level unspecified	0.001	0.998	0.000
T09.0 Superficial injury of trunk, level unspecified	0.001	0.998	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.001	0.998	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.001	0.998	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.001	0.998	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.001	0.998	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.001	0.998	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.001	0.998	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.001	0.998	0.000
T11.1 Open wound of upper limb, level unspecified	0.001	0.998	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.001	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.001	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
T14.2 Fracture of unspecified body region	0.001	0.998	0.000
T14.9 Injury, unspecified	0.001	0.998	0.000
T14.8 Other injuries of unspecified body region	0.001	0.998	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.001	0.998	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.001	0.998	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.001	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.001	0.998	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.001	0.998	0.000
T14.1 Open wound of unspecified body region	0.001	0.998	0.000
N30 Cystitis	0.002	0.998	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.001	0.998	0.000
T05 Traumatic amputations involving multiple body regions	0.001	0.998	0.000
T04 Crushing injuries involving multiple body regions	0.001	0.998	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.001	0.998	0.000
T02 Fractures involving multiple body regions	0.001	0.998	0.000
T01 Open wounds involving multiple body regions	0.001	0.998	0.000
T00 Superficial injuries involving multiple body regions	0.001	0.998	0.000
T07 Unspecified multiple injuries	0.001	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.001	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
T21 Burn and corrosion of trunk	0.001	0.998	0.000
T20 Burn and corrosion of head and neck	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations