TreeWAS – Variant ID: rs7309767

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.419	0.581	0.000
E03.1 Congenital hypothyroidism without goitre	0.317	0.683	0.000
E03.5 Myxoedema coma	0.300	0.699	0.000
E03.4 Atrophy of thyroid (acquired)	0.300	0.699	0.000
E03.3 Postinfectious hypothyroidism	0.300	0.699	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.291	0.709	0.000
E03.8 Other specified hypothyroidism	0.265	0.735	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.253	0.746	0.000
E00-E07 Disorders of thyroid gland	0.172	0.828	0.000
E06 Thyroiditis	0.165	0.835	0.000
E06.3 Autoimmune thyroiditis	0.161	0.839	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.146	0.854	0.000
E06.1 Subacute thyroiditis	0.124	0.876	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.124	0.876	0.000
E00 Congenital iodine-deficiency syndrome	0.124	0.876	0.000
E06.5 Other chronic thyroiditis	0.121	0.879	0.000
E06.4 Drug-induced thyroiditis	0.119	0.881	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.119	0.881	0.000
E06.0 Acute thyroiditis	0.119	0.881	0.000
E06.9 Thyroiditis, unspecified	0.107	0.893	0.000
E07 Other disorders of thyroid	0.101	0.899	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.089	0.911	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.089	0.911	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.089	0.911	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.089	0.911	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.089	0.911	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.089	0.911	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.089	0.911	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.089	0.911	0.000
E07.1 Dyshormogenetic goitre	0.072	0.928	0.000
E07.0 Hypersecretion of calcitonin	0.072	0.928	0.000
E07.8 Other specified disorders of thyroid	0.069	0.931	0.000
E07.9 Disorder of thyroid, unspecified	0.054	0.946	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.954	0.046
H02.3 Blepharochalasis	0.039	0.961	0.000
T51.0 Ethanol	0.037	0.963	0.000
E04 Other non-toxic goitre	0.033	0.967	0.000
E04.8 Other specified non-toxic goitre	0.024	0.976	0.000
E04.0 Non-toxic diffuse goitre	0.023	0.977	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.023	0.977	0.000
E04.9 Non-toxic goitre, unspecified	0.023	0.977	0.000
T51 Toxic effect of alcohol	0.021	0.979	0.000
Z99.3 Dependence on wheelchair	0.020	0.980	0.000
E05.8 Other thyrotoxicosis	0.017	0.983	0.000
E05.5 Thyroid crisis or storm	0.016	0.983	0.000
E05.4 Thyrotoxicosis factitia	0.016	0.983	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.016	0.983	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.016	0.983	0.000
T51.8 Other alcohols	0.015	0.984	0.000
T51.3 Fusel oil	0.015	0.984	0.000
T51.2 2-Propanol	0.015	0.984	0.000
T51.1 Methanol	0.015	0.984	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.015	0.985	0.000
T63 Toxic effect of contact with venomous animals	0.014	0.986	0.000
T63.4 Venom of other arthropods	0.014	0.986	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.014	0.986	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.014	0.986	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.014	0.986	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.014	0.986	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.013	0.987	0.000
T40.6 Other and unspecified narcotics	0.013	0.987	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.013	0.987	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
T45.0 Antiallergic and antiemetic drugs	0.012	0.988	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.012	0.988	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.012	0.988	0.000
E20-E35 Disorders of other endocrine glands	0.012	0.988	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.011	0.989	0.000
T62 Toxic effect of other noxious substances eaten as food	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T51.9 Alcohol, unspecified	0.011	0.989	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
T45.5 Anticoagulants	0.011	0.989	0.000
T56 Toxic effect of metals	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.011	0.989	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.011	0.989	0.000
T60 Toxic effect of pesticides	0.011	0.989	0.000
T57 Toxic effect of other inorganic substances	0.011	0.989	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.011	0.989	0.000
T52 Toxic effect of organic solvents	0.011	0.989	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.011	0.989	0.000
T55 Toxic effect of soaps and detergents	0.011	0.989	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.011	0.989	0.000
T58 Toxic effect of carbon monoxide	0.011	0.989	0.000
T54 Toxic effect of corrosive substances	0.011	0.989	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.011	0.989	0.000
T63.8 Toxic effect of contact with other venomous animals	0.010	0.989	0.000
T63.6 Toxic effect of contact with other marine animals	0.010	0.989	0.000
T63.5 Toxic effect of contact with fish	0.010	0.989	0.000
T63.3 Venom of spider	0.010	0.989	0.000
T63.2 Venom of scorpion	0.010	0.989	0.000
T63.1 Venom of other reptiles	0.010	0.989	0.000
T63.0 Snake venom	0.010	0.989	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.011	0.989	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.011	0.989	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.011	0.989	0.000
T45.4 Iron and its compounds	0.010	0.989	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.010	0.989	0.000
T65 Toxic effect of other and unspecified substances	0.010	0.990	0.000
T40.1 Heroin	0.010	0.990	0.000
T36 Poisoning by systemic antibiotics	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.990	0.000
T50.4 Drugs affecting uric acid metabolism	0.010	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
T43.9 Psychotropic drug, unspecified	0.010	0.990	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
T40.4 Other synthetic narcotics	0.010	0.990	0.000
E50-E64 Other nutritional deficiencies	0.010	0.990	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.010	0.990	0.000
T45.8 Other primarily systemic and haematological agents	0.010	0.990	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.010	0.990	0.000
T45.6 Fibrinolysis-affecting drugs	0.010	0.990	0.000
T45.3 Enzymes, not elsewhere classified	0.010	0.990	0.000
T39.4 Antirheumatics, not elsewhere classified	0.010	0.990	0.000
T39.2 Pyrazolone derivatives	0.010	0.990	0.000
T50.7 Analeptics and opioid receptor antagonists	0.010	0.990	0.000
T50.5 Appetite depressants	0.010	0.990	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.010	0.990	0.000
T50.0 Mineralocorticoids and their antagonists	0.010	0.990	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.010	0.990	0.000
E20 Hypoparathyroidism	0.010	0.990	0.000
T40.5 Cocaine	0.010	0.990	0.000
E25 Adrenogenital disorders	0.010	0.990	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.010	0.990	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.010	0.990	0.000
T40.8 Lysergide [LSD]	0.010	0.990	0.000
T40.7 Cannabis (derivatives)	0.010	0.990	0.000
T40.3 Methadone	0.010	0.990	0.000
T40.0 Opium	0.010	0.990	0.000
E28 Ovarian dysfunction	0.010	0.990	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.009	0.990	0.000
E29 Testicular dysfunction	0.009	0.991	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.009	0.991	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
T43.2 Other and unspecified antidepressants	0.009	0.991	0.000
T59 Toxic effect of other gases, fumes and vapours	0.009	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
T62.9 Noxious substance eaten as food, unspecified	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
E61 Deficiency of other nutrient elements	0.009	0.991	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.009	0.991	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.009	0.991	0.000
E26 Hyperaldosteronism	0.009	0.991	0.000
E40-E46 Malnutrition	0.009	0.991	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.008	0.991	0.000
E32 Diseases of thymus	0.008	0.991	0.000
E31 Polyglandular dysfunction	0.008	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.008	0.991	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.992	0.000
T62.8 Other specified noxious substances eaten as food	0.008	0.992	0.000
T62.2 Other ingested (parts of) plant(s)	0.008	0.992	0.000
T62.1 Ingested berries	0.008	0.992	0.000
T62.0 Ingested mushrooms	0.008	0.992	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.008	0.992	0.000
T39.0 Salicylates	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.008	0.992	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.008	0.992	0.000
T44.0 Anticholinesterase agents	0.008	0.992	0.000
E28.3 Primary ovarian failure	0.008	0.992	0.000
T56.8 Other metals	0.008	0.992	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
T56.9 Metal, unspecified	0.008	0.992	0.000
T56.7 Beryllium and its compounds	0.008	0.992	0.000
T56.6 Tin and its compounds	0.008	0.992	0.000
T56.5 Zinc and its compounds	0.008	0.992	0.000
T56.4 Copper and its compounds	0.008	0.992	0.000
T56.3 Cadmium and its compounds	0.008	0.992	0.000
T56.2 Chromium and its compounds	0.008	0.992	0.000
T56.1 Mercury and its compounds	0.008	0.992	0.000
T56.0 Lead and its compounds	0.008	0.992	0.000
T52.9 Organic solvent, unspecified	0.008	0.992	0.000
T52.8 Other organic solvents	0.008	0.992	0.000
T52.4 Ketones	0.008	0.992	0.000
T52.3 Glycols	0.008	0.992	0.000
T52.2 Homologues of benzene	0.008	0.992	0.000
T52.1 Benzene	0.008	0.992	0.000
T52.0 Petroleum products	0.008	0.992	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.008	0.992	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.008	0.992	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.008	0.992	0.000
T53.5 Chlorofluorocarbons	0.008	0.992	0.000
T53.4 Dichloromethane	0.008	0.992	0.000
T53.3 Tetrachloroethylene	0.008	0.992	0.000
T53.2 Trichloroethylene	0.008	0.992	0.000
T53.1 Chloroform	0.008	0.992	0.000
T53.0 Carbon tetrachloride	0.008	0.992	0.000
T57.9 Inorganic substance, unspecified	0.008	0.992	0.000
T57.8 Other specified inorganic substances	0.008	0.992	0.000
T57.3 Hydrogen cyanide	0.008	0.992	0.000
T57.2 Manganese and its compounds	0.008	0.992	0.000
T57.1 Phosphorus and its compounds	0.008	0.992	0.000
T57.0 Arsenic and its compounds	0.008	0.992	0.000
T60.9 Pesticide, unspecified	0.008	0.992	0.000
T60.8 Other pesticides	0.008	0.992	0.000
T60.4 Rodenticides	0.008	0.992	0.000
T60.3 Herbicides and fungicides	0.008	0.992	0.000
T60.2 Other insecticides	0.008	0.992	0.000
T60.1 Halogenated insecticides	0.008	0.992	0.000
T60.0 Organophosphate and carbamate insecticides	0.008	0.992	0.000
T61.9 Toxic effect of unspecified seafood	0.008	0.992	0.000
T61.8 Toxic effect of other seafoods	0.008	0.992	0.000
T61.2 Other fish and shellfish poisoning	0.008	0.992	0.000
T61.1 Scombroid fish poisoning	0.008	0.992	0.000
T61.0 Ciguatera fish poisoning	0.008	0.992	0.000
E63 Other nutritional deficiencies	0.008	0.992	0.000
E20.8 Other hypoparathyroidism	0.008	0.992	0.000
T49.9 Topical agent, unspecified	0.008	0.992	0.000
T49.8 Other topical agents	0.008	0.992	0.000
T49.7 Dental drugs, topically applied	0.008	0.992	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.992	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.992	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.992	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.992	0.000
T49.2 Local astringents and local detergents	0.008	0.992	0.000
T49.1 Antipruritics	0.008	0.992	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.008	0.992	0.000
T54.2 Corrosive acids and acid-like substances	0.008	0.992	0.000
T54.1 Other corrosive organic compounds	0.008	0.992	0.000
T54.0 Phenol and phenol homologues	0.008	0.992	0.000
T36.4 Tetracyclines	0.008	0.992	0.000
E20.9 Hypoparathyroidism, unspecified	0.008	0.992	0.000
E27 Other disorders of adrenal gland	0.008	0.992	0.000
E23.7 Disorder of pituitary gland, unspecified	0.008	0.992	0.000
E29.1 Testicular hypofunction	0.008	0.992	0.000
T41.5 Therapeutic gases	0.008	0.992	0.000
T41.4 Anaesthetic, unspecified	0.008	0.992	0.000
T41.3 Local anaesthetics	0.008	0.992	0.000
T41.1 Intravenous anaesthetics	0.008	0.992	0.000
T41.0 Inhaled anaesthetics	0.008	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.992	0.000
T46.7 Peripheral vasodilators	0.008	0.992	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
T54.9 Corrosive substance, unspecified	0.008	0.992	0.000
E61.1 Iron deficiency	0.008	0.992	0.000
E24.9 Cushing's syndrome, unspecified	0.008	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
T65.8 Toxic effect of other specified substances	0.007	0.992	0.000
T65.6 Paints and dyes, not elsewhere classified	0.007	0.992	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.007	0.992	0.000
T65.4 Carbon disulphide	0.007	0.992	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.007	0.992	0.000
T65.2 Tobacco and nicotine	0.007	0.992	0.000
T65.1 Strychnine and its salts	0.007	0.992	0.000
T65.0 Cyanides	0.007	0.992	0.000
T36.9 Systemic antibiotic, unspecified	0.007	0.992	0.000
T36.8 Other systemic antibiotics	0.007	0.992	0.000
T36.7 Antifungal antibiotics, systemically used	0.007	0.992	0.000
T36.6 Rifamycins	0.007	0.992	0.000
T36.5 Aminoglycosides	0.007	0.992	0.000
T36.2 Chloramphenicol group	0.007	0.992	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.007	0.992	0.000
D22.4 Melanocytic naevi of scalp and neck	0.008	0.992	0.000
E58 Dietary calcium deficiency	0.008	0.992	0.000
E51 Thiamine deficiency	0.007	0.992	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.992	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.992	0.000
T48.4 Expectorants	0.007	0.992	0.000
T48.3 Antitussives	0.007	0.992	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.992	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.992	0.000
T48.0 Oxytocic drugs	0.007	0.992	0.000
T36.0 Penicillins	0.007	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.992	0.000
N81.8 Other female genital prolapse	0.008	0.992	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.007	0.993	0.000
E50 Vitamin A deficiency	0.007	0.993	0.000
E60 Dietary zinc deficiency	0.007	0.993	0.000
E59 Dietary selenium deficiency	0.007	0.993	0.000
E52 Niacin deficiency [pellagra]	0.007	0.993	0.000
E54 Ascorbic acid deficiency	0.007	0.993	0.000
T36.3 Macrolides	0.007	0.993	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
T37.5 Antiviral drugs	0.007	0.993	0.000
T37.4 Anthelminthics	0.007	0.993	0.000
T37.3 Other antiprotozoal drugs	0.007	0.993	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
T37.1 Antimycobacterial drugs	0.007	0.993	0.000
T37.0 Sulphonamides	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
E20.1 Pseudohypoparathyroidism	0.007	0.993	0.000
E20.0 Idiopathic hypoparathyroidism	0.007	0.993	0.000
E56 Other vitamin deficiencies	0.007	0.993	0.000
T65.9 Toxic effect of unspecified substance	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.993	0.000
E25.8 Other adrenogenital disorders	0.007	0.993	0.000
D22 Melanocytic naevi	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
T48.5 Anti-common-cold drugs	0.007	0.993	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.007	0.993	0.000
E28.9 Ovarian dysfunction, unspecified	0.007	0.993	0.000
E28.8 Other ovarian dysfunction	0.007	0.993	0.000
E28.1 Androgen excess	0.007	0.993	0.000
E28.0 Oestrogen excess	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.007	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
T47.7 Emetics	0.007	0.993	0.000
T47.5 Digestants	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T47.3 Saline and osmotic laxatives	0.007	0.993	0.000
T47.2 Stimulant laxatives	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.007	0.993	0.000
E26.9 Hyperaldosteronism, unspecified	0.007	0.993	0.000
E29.9 Testicular dysfunction, unspecified	0.007	0.993	0.000
E29.8 Other testicular dysfunction	0.007	0.993	0.000
E29.0 Testicular hyperfunction	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.007	0.993	0.000
T40.2 Other opioids	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
T59.7 Carbon dioxide	0.007	0.993	0.000
T59.6 Hydrogen sulphide	0.007	0.993	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.007	0.993	0.000
T59.4 Chlorine gas	0.007	0.993	0.000
T59.3 Lachrymogenic gas	0.007	0.993	0.000
T59.2 Formaldehyde	0.007	0.993	0.000
T59.1 Sulphur dioxide	0.007	0.993	0.000
T59.0 Nitrogen oxides	0.007	0.993	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.007	0.993	0.000
E61.2 Magnesium deficiency	0.007	0.993	0.000
T59.9 Gases, fumes and vapours, unspecified	0.006	0.993	0.000
E63.9 Nutritional deficiency, unspecified	0.007	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.993	0.000
E24.1 Nelson's syndrome	0.006	0.993	0.000
E53 Deficiency of other B group vitamins	0.007	0.993	0.000
E61.9 Deficiency of nutrient element, unspecified	0.006	0.993	0.000
E61.8 Deficiency of other specified nutrient elements	0.006	0.993	0.000
E61.7 Deficiency of multiple nutrient elements	0.006	0.993	0.000
E61.6 Vanadium deficiency	0.006	0.993	0.000
E61.5 Molybdenum deficiency	0.006	0.993	0.000
E61.4 Chromium deficiency	0.006	0.993	0.000
E61.3 Manganese deficiency	0.006	0.993	0.000
E61.0 Copper deficiency	0.006	0.993	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.007	0.993	0.000
E04.2 Non-toxic multinodular goitre	0.006	0.993	0.000
E26.8 Other hyperaldosteronism	0.006	0.993	0.000
E26.1 Secondary hyperaldosteronism	0.006	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.006	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.006	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.006	0.993	0.000
E42 Marasmic kwashiorkor	0.006	0.993	0.000
E41 Nutritional marasmus	0.006	0.993	0.000
E40 Kwashiorkor	0.006	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
M22.8 Other disorders of patella	0.006	0.994	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.994	0.000
E30.8 Other disorders of puberty	0.006	0.994	0.000
E30.1 Precocious puberty	0.006	0.994	0.000
E30.0 Delayed puberty	0.006	0.994	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.994	0.000
E31.8 Other polyglandular dysfunction	0.006	0.994	0.000
E31.1 Polyglandular hyperfunction	0.006	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.006	0.994	0.000
E32.9 Disease of thymus, unspecified	0.006	0.994	0.000
E32.8 Other diseases of thymus	0.006	0.994	0.000
E32.1 Abscess of thymus	0.006	0.994	0.000
E32.0 Persistent hyperplasia of thymus	0.006	0.994	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.994	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.994	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.006	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.006	0.994	0.000
E22.1 Hyperprolactinaemia	0.006	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.006	0.994	0.000
D22.0 Melanocytic naevi of lip	0.006	0.994	0.000
E65 Localised adiposity	0.006	0.994	0.000
D22.9 Melanocytic naevi, unspecified	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
E34 Other endocrine disorders	0.006	0.994	0.000
E22.0 Acromegaly and pituitary gigantism	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
E63.8 Other specified nutritional deficiencies	0.006	0.994	0.000
E63.1 Imbalance of constituents of food intake	0.006	0.994	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.006	0.994	0.000
E55 Vitamin D deficiency	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.006	0.994	0.000
E27.0 Other adrenocortical overactivity	0.006	0.994	0.000
E26.0 Primary hyperaldosteronism	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
Z99.2 Dependence on renal dialysis	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
E67 Other hyperalimentation	0.006	0.994	0.000
E68 Sequelae of hyperalimentation	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
E51.2 Wernicke's encephalopathy	0.006	0.994	0.000
E46 Unspecified protein-energy malnutrition	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
T91.1 Sequelae of fracture of spine	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
E27.8 Other specified disorders of adrenal gland	0.006	0.994	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.994	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.994	0.000
E51.1 Beriberi	0.005	0.994	0.000
T46.1 Calcium-channel blockers	0.005	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.005	0.994	0.000
E50.8 Other manifestations of vitamin A deficiency	0.005	0.994	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.005	0.994	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.005	0.994	0.000
E50.5 Vitamin A deficiency with night blindness	0.005	0.994	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.005	0.994	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.005	0.994	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.005	0.994	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.005	0.994	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.005	0.994	0.000
E53.9 Vitamin B deficiency, unspecified	0.006	0.994	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.005	0.994	0.000
E64.8 Sequelae of other nutritional deficiencies	0.005	0.994	0.000
E64.3 Sequelae of rickets	0.005	0.994	0.000
E64.2 Sequelae of vitamin C deficiency	0.005	0.994	0.000
E64.1 Sequelae of vitamin A deficiency	0.005	0.994	0.000
E64.0 Sequelae of protein-energy malnutrition	0.005	0.994	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.994	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.006	0.994	0.000
E56.9 Vitamin deficiency, unspecified	0.005	0.994	0.000
E56.8 Deficiency of other vitamins	0.005	0.994	0.000
E56.0 Deficiency of vitamin E	0.005	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.005	0.994	0.000
Z99.4 Dependence on artificial heart	0.005	0.995	0.000
Z99.0 Dependence on aspirator	0.005	0.995	0.000
T42.3 Barbiturates	0.005	0.995	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.005	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.005	0.995	0.000
E23.0 Hypopituitarism	0.005	0.995	0.000
T59.8 Other specified gases, fumes and vapours	0.005	0.995	0.000
H26.2 Complicated cataract	0.005	0.995	0.000
E53.1 Pyridoxine deficiency	0.005	0.995	0.000
E53.0 Riboflavin deficiency	0.005	0.995	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.005	0.995	0.000
Z99.1 Dependence on respirator	0.005	0.995	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
J98.4 Other disorders of lung	0.000	0.995	0.005
T91 Sequelae of injuries of neck and trunk	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E15 Nondiabetic hypoglycaemic coma	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.004	0.995	0.000
E34.4 Constitutional tall stature	0.004	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.995	0.000
E55.0 Rickets, active	0.004	0.995	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.995	0.005
E21.3 Hyperparathyroidism, unspecified	0.005	0.995	0.000
E27.2 Addisonian crisis	0.004	0.995	0.000
T91.3 Sequelae of injury of spinal cord	0.005	0.995	0.000
E67.8 Other specified hyperalimentation	0.004	0.995	0.000
E67.3 Hypervitaminosis D	0.004	0.995	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.995	0.000
E67.1 Hypercarotenaemia	0.004	0.995	0.000
E67.0 Hypervitaminosis A	0.004	0.995	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.995	0.004
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.995	0.005
N92.0 Excessive and frequent menstruation with regular cycle	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
S19.9 Unspecified injury of neck	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations