TreeWAS – Variant ID: rs7323885

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.001	0.456	0.543
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.537	0.463
E03.5 Myxoedema coma	0.001	0.610	0.389
E03.4 Atrophy of thyroid (acquired)	0.001	0.610	0.389
E03.3 Postinfectious hypothyroidism	0.001	0.610	0.389
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.610	0.389
E03.8 Other specified hypothyroidism	0.001	0.615	0.385
E03.1 Congenital hypothyroidism without goitre	0.001	0.635	0.365
I63.9 Cerebral infarction, unspecified	0.000	0.786	0.214
K31.1 Adult hypertrophic pyloric stenosis	0.078	0.922	0.000
E04.2 Non-toxic multinodular goitre	0.078	0.922	0.000
E04 Other non-toxic goitre	0.048	0.950	0.002
N39.3 Stress incontinence	0.000	0.951	0.049
E04.9 Non-toxic goitre, unspecified	0.047	0.953	0.000
K31.5 Obstruction of duodenum	0.046	0.954	0.000
K31 Other diseases of stomach and duodenum	0.043	0.957	0.000
Y85.0 Sequelae of motor-vehicle accident	0.036	0.964	0.000
E04.8 Other specified non-toxic goitre	0.035	0.964	0.001
K31.6 Fistula of stomach and duodenum	0.033	0.966	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.032	0.967	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.033	0.967	0.000
K31.0 Acute dilatation of stomach	0.031	0.969	0.000
E04.0 Non-toxic diffuse goitre	0.030	0.969	0.001
K31.3 Pylorospasm, not elsewhere classified	0.030	0.970	0.000
K31.4 Gastric diverticulum	0.029	0.971	0.000
E00-E07 Disorders of thyroid gland	0.006	0.975	0.020
D72.8 Other specified disorders of white blood cells	0.021	0.979	0.000
I63 Cerebral infarction	0.000	0.981	0.019
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.981	0.015
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.982	0.014
E00 Congenital iodine-deficiency syndrome	0.004	0.982	0.014
E04.1 Non-toxic single thyroid nodule	0.018	0.982	0.001
E07 Other disorders of thyroid	0.003	0.984	0.013
D72 Other disorders of white blood cells	0.015	0.985	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.986	0.014
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.986	0.014
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.014	0.986	0.000
D75 Other diseases of blood and blood-forming organs	0.014	0.986	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.003	0.987	0.010
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.003	0.987	0.010
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.003	0.987	0.010
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.003	0.987	0.010
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.987	0.010
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.003	0.987	0.010
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.003	0.987	0.010
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.003	0.987	0.010
N93.0 Postcoital and contact bleeding	0.013	0.987	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.988	0.012
O14.9 Preeclampsia, unspecified	0.000	0.988	0.012
I63.8 Other cerebral infarction	0.000	0.988	0.012
Y85 Sequelae of transport accidents	0.012	0.988	0.000
E07.1 Dyshormogenetic goitre	0.002	0.988	0.010
E07.0 Hypersecretion of calcitonin	0.002	0.988	0.010
E06 Thyroiditis	0.004	0.988	0.008
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.989	0.011
H35.9 Retinal disorder, unspecified	0.011	0.989	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.011	0.989	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.011	0.989	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.011	0.989	0.000
D72.9 Disorder of white blood cells, unspecified	0.011	0.989	0.000
D72.0 Genetic anomalies of leukocytes	0.011	0.989	0.000
D75.2 Essential thrombocytosis	0.011	0.989	0.000
E07.9 Disorder of thyroid, unspecified	0.001	0.989	0.010
D75.0 Familial erythrocytosis	0.010	0.990	0.000
D72.1 Eosinophilia	0.010	0.990	0.000
H35 Other retinal disorders	0.010	0.990	0.000
E07.8 Other specified disorders of thyroid	0.002	0.990	0.008
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.990	0.009
H35.6 Retinal haemorrhage	0.009	0.991	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.991	0.009
H35.4 Peripheral retinal degeneration	0.009	0.991	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.009	0.991	0.000
H35.8 Other specified retinal disorders	0.009	0.991	0.000
H35.7 Separation of retinal layers	0.009	0.991	0.000
E06.4 Drug-induced thyroiditis	0.003	0.991	0.006
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.991	0.006
E06.0 Acute thyroiditis	0.003	0.991	0.006
D74 Methaemoglobinaemia	0.008	0.992	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.008	0.992	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.008	0.992	0.000
E06.5 Other chronic thyroiditis	0.003	0.992	0.005
E06.1 Subacute thyroiditis	0.003	0.992	0.005
H35.1 Retinopathy of prematurity	0.007	0.993	0.000
D76.3 Other histiocytosis syndromes	0.007	0.993	0.000
E06.9 Thyroiditis, unspecified	0.003	0.993	0.004
H35.2 Other proliferative retinopathy	0.007	0.993	0.000
H35.0 Background retinopathy and retinal vascular changes	0.007	0.993	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.007	0.993	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.007	0.993	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.007	0.993	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.007	0.993	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.993	0.007
D73 Diseases of spleen	0.007	0.993	0.000
D74.9 Methaemoglobinaemia, unspecified	0.006	0.994	0.000
D74.8 Other methaemoglobinaemias	0.006	0.994	0.000
D74.0 Congenital methaemoglobinaemia	0.006	0.994	0.000
H35.5 Hereditary retinal dystrophy	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.002	0.994	0.004
D73.3 Abscess of spleen	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.994	0.006
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.995	0.002
R94.4 Abnormal results of kidney function studies	0.000	0.995	0.005
C71.3 Parietal lobe	0.005	0.995	0.000
D73.9 Disease of spleen, unspecified	0.005	0.995	0.000
D73.2 Chronic congestive splenomegaly	0.005	0.995	0.000
D73.0 Hyposplenism	0.005	0.995	0.000
O14.0 Moderate preeclampsia	0.000	0.995	0.005
D73.8 Other diseases of spleen	0.005	0.995	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.005	0.995	0.000
H35.3 Degeneration of macula and posterior pole	0.005	0.995	0.000
D73.1 Hypersplenism	0.004	0.995	0.000
C45.9 Mesothelioma, unspecified	0.000	0.995	0.004
O14.2 HELLP syndrome	0.000	0.995	0.004
C71 Malignant neoplasm of brain	0.004	0.996	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
C71.2 Temporal lobe	0.004	0.996	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.004	0.996	0.001
E05.5 Thyroid crisis or storm	0.002	0.996	0.002
E05.4 Thyrotoxicosis factitia	0.002	0.996	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.996	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.996	0.002
C71.9 Brain, unspecified	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.002	0.996	0.002
O14.1 Severe preeclampsia	0.000	0.996	0.004
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.996	0.004
C45.7 Mesothelioma of other sites	0.000	0.996	0.004
C45 Mesothelioma	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.004	0.996	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.004	0.996	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
N90.4 Leukoplakia of vulva	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.004	0.996	0.000
C71.7 Brain stem	0.003	0.996	0.000
C71.6 Cerebellum	0.003	0.996	0.000
D70 Agranulocytosis	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
Z57.2 Occupational exposure to dust	0.000	0.997	0.003
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
C71.4 Occipital lobe	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
D73.5 Infarction of spleen	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
D41.0 Kidney	0.000	0.997	0.003
G93.3 Postviral fatigue syndrome	0.000	0.997	0.003
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
H61.2 Impacted cerumen	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
M34 Systemic sclerosis	0.000	0.997	0.003
G54.0 Brachial plexus disorders	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
S82.50 Fracture of medial malleolus (closed)	0.002	0.997	0.000
I30 Acute pericarditis	0.000	0.997	0.002
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
G54.8 Other nerve root and plexus disorders	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
T87.4 Infection of amputation stump	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
G54.1 Lumbosacral plexus disorders	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.002
N90 Other noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
G54.6 Phantom limb syndrome with pain	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.998	0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
H81 Disorders of vestibular function	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
F32.8 Other depressive episodes	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
Z43.2 Attention to ileostomy	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
N90.7 Vulvar cyst	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
C69.9 Eye, unspecified	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
B27.9 Infectious mononucleosis, unspecified	0.002	0.998	0.000
G54.7 Phantom limb syndrome without pain	0.002	0.998	0.000
G54.5 Neuralgic amyotrophy	0.002	0.998	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.002	0.998	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.998	0.002
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
N90.6 Hypertrophy of vulva	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.998	0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
I30.1 Infective pericarditis	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
D28.0 Vulva	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.000	0.998	0.002
H93.1 Tinnitus	0.000	0.998	0.002
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
X62.9 Unspecified place	0.000	0.998	0.002
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
B33.8 Other specified viral diseases	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.000	0.998	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
C72.0 Spinal cord	0.002	0.998	0.000
C69.6 Orbit	0.001	0.998	0.000
C72.9 Central nervous system, unspecified	0.001	0.998	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.998	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.998	0.000
C72.4 Acoustic nerve	0.001	0.998	0.000
C72.3 Optic nerve	0.001	0.998	0.000
C72.2 Olfactory nerve	0.001	0.998	0.000
C72.1 Cauda equina	0.001	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
T87.5 Necrosis of amputation stump	0.000	0.998	0.002
T88.2 Shock due to anaesthesia	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
N90.0 Mild vulvar dysplasia	0.001	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.000	0.998	0.001
T87.1 Complications of reattached (part of) lower extremity	0.000	0.998	0.001
T87.0 Complications of reattached (part of) upper extremity	0.000	0.998	0.001
C69.0 Conjunctiva	0.001	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
B27.0 Gammaherpesviral mononucleosis	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.001	0.998	0.000
C70.1 Spinal meninges	0.001	0.998	0.000
N90.3 Dysplasia of vulva, unspecified	0.001	0.998	0.000
B27 Infectious mononucleosis	0.002	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.001	0.998	0.000
B33 Other viral diseases, not elsewhere classified	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.001	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.000	0.998	0.001
N90.1 Moderate vulvar dysplasia	0.001	0.998	0.000
B33.2 Viral carditis	0.001	0.998	0.000
B33.0 Epidemic myalgia	0.001	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.001
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.001	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
S86.00 Unspecified injury of Achilles tendon	0.001	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
J99.0 Rheumatoid lung disease	0.000	0.998	0.001
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
M23.41 Loose body in knee-Ant lig/hrn men	0.001	0.998	0.000
C70.0 Cerebral meninges	0.001	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.001	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.001	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.001	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.001	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.001	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.001	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.001
Z57.7 Occupational exposure to vibration	0.000	0.998	0.001
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.001
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.001
Z57.1 Occupational exposure to radiation	0.000	0.998	0.001
Z57.0 Occupational exposure to noise	0.000	0.998	0.001
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.999	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.999	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.999	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
H60.5 Acute otitis externa, non-infective	0.001	0.999	0.000
T88.9 Complication of surgical and medical care, unspecified	0.001	0.999	0.000
F33.8 Other recurrent depressive disorders	0.000	0.999	0.001
M41.3 Thoracogenic scoliosis	0.001	0.999	0.000
M41.2 Other idiopathic scoliosis	0.001	0.999	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.999	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.999	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.999	0.000
H60.3 Other infective otitis externa	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.001	0.999	0.000
N64.5 Other signs and symptoms in breast	0.000	0.999	0.001
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.001	0.999	0.000
O46.9 Antepartum haemorrhage, unspecified	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.999	0.000
B27.8 Other infectious mononucleosis	0.001	0.999	0.000
B27.1 Cytomegaloviral mononucleosis	0.001	0.999	0.000
B35.3 Tinea pedis	0.000	0.999	0.001
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.999	0.001
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.999	0.000
K75.9 Inflammatory liver disease, unspecified	0.001	0.999	0.000
H60 Otitis externa	0.001	0.999	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.999	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.999	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.999	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.999	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.999	0.000
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.001	0.999	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.001	0.999	0.000
B33.1 Ross River disease	0.001	0.999	0.000
H61.9 Disorder of external ear, unspecified	0.001	0.999	0.000
J20.8 Acute bronchitis due to other specified organisms	0.000	0.999	0.001
M67.8 Other specified disorders of synovium and tendon	0.001	0.999	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.999	0.001
H60-H62 Diseases of external ear	0.001	0.999	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.999	0.000
D37.5 Rectum	0.000	0.999	0.001
K83.1 Obstruction of bile duct	0.001	0.999	0.000
M41.5 Other secondary scoliosis	0.001	0.999	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.001
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.999	0.001
H60.8 Other otitis externa	0.001	0.999	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.999	0.001
T88.3 Malignant hyperthermia due to anaesthesis	0.001	0.999	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.001	0.999	0.000
T88.0 Infection following immunisation	0.001	0.999	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.999	0.001
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.999	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.999	0.001
H60.4 Cholesteatoma of external ear	0.001	0.999	0.000
J31.0 Chronic rhinitis	0.000	0.999	0.001
F32 Depressive episode	0.000	0.999	0.001
F39 Unspecified mood [affective] disorder	0.000	0.999	0.001
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.999	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.999	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.999	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.999	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.999	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.999	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
H60.0 Abscess of external ear	0.001	0.999	0.000
T88.4 Failed or difficult intubation	0.001	0.999	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
S89.9 Unspecified injury of lower leg	0.001	0.999	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.001	0.999	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.999	0.001
H62.8 Other disorders of external ear in diseases classified elsewhere	0.001	0.999	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.001	0.999	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H62.2 Otitis externa in mycoses	0.001	0.999	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.001	0.999	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.999	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.999	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.999	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.999	0.000
H60.1 Cellulitis of external ear	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.999	0.000
J20 Acute bronchitis	0.000	0.999	0.001
S87 Crushing injury of lower leg	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
H60.2 Malignant otitis externa	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.000
Q51.2 Other doubling of uterus	0.001	0.999	0.000
H55 Nystagmus and other irregular eye movements	0.001	0.999	0.000
S80-S89 Injuries to the knee and lower leg	0.001	0.999	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.999	0.001
I42.9 Cardiomyopathy, unspecified	0.000	0.999	0.001
M23.4 Loose body in knee	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.999	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
M23.46 Loose body in knee-O/unsp lat men	0.001	0.999	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.001	0.999	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.000	0.999	0.001
O36.4 Maternal care for intra-uterine death	0.000	0.999	0.001
S82.0 Fracture of patella	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations