TreeWAS – Variant ID: rs73931391

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O68 Labour and delivery complicated by foetal stress [distress]	0.061	0.939
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.059	0.941
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.056	0.944
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.053	0.947
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.051	0.949
O60-O75 Complications of labour and delivery	0.049	0.951
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.049	0.951
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.044	0.956
O66 Other obstructed labour	0.041	0.959
O71 Other obstetric trauma	0.041	0.959
O63 Long labour	0.040	0.960
O73 Retained placenta and membranes, without haemorrhage	0.038	0.961
O62 Abnormalities of forces of labour	0.038	0.962
O71.4 Obstetric high vaginal laceration alone	0.035	0.964
O74 Complications of anaesthesia during labour and delivery	0.035	0.965
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.035	0.965
O65 Obstructed labour due to maternal pelvic abnormality	0.035	0.965
O61 Failed induction of labour	0.035	0.965
O60 Preterm delivery	0.035	0.965
O64 Obstructed labour due to malposition and malpresentation of foetus	0.034	0.965
O69 Labour and delivery complicated by umbilical cord complications	0.034	0.966
O63.9 Long labour, unspecified	0.034	0.966
O66.0 Obstructed labour due to shoulder dystocia	0.033	0.967
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.033	0.967
O70 Perineal laceration during delivery	0.032	0.968
O75 Other complications of labour and delivery, not elsewhere classified	0.031	0.969
O73.0 Retained placenta, without haemorrhage	0.031	0.969
O62.2 Other uterine inertia	0.030	0.970
O66.9 Obstructed labour, unspecified	0.030	0.970
O66.8 Other specified obstructed labour	0.030	0.970
O66.4 Failed trial of labour, unspecified	0.030	0.970
O66.3 Obstructed labour due to other abnormalities of foetus	0.030	0.970
O66.2 Obstructed labour due to unusually large foetus	0.030	0.970
O66.1 Obstructed labour due to locked twins	0.030	0.970
O72 Postpartum haemorrhage	0.030	0.970
O71.9 Obstetric trauma, unspecified	0.030	0.970
O71.8 Other specified obstetric trauma	0.030	0.970
O71.7 Obstetric haematoma of pelvis	0.030	0.970
O71.6 Obstetric damage to pelvic joints and ligaments	0.030	0.970
O71.5 Other obstetric injury to pelvic organs	0.030	0.970
O71.3 Obstetric laceration of cervix	0.030	0.970
O71.2 Postpartum inversion of uterus	0.030	0.970
O71.1 Rupture of uterus during labour	0.030	0.970
O71.0 Rupture of uterus before onset of labour	0.030	0.970
O63.1 Prolonged second stage (of labour)	0.029	0.971
O63.2 Delayed delivery of second twin, triplet, etc.	0.029	0.971
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.029	0.971
O63.0 Prolonged first stage (of labour)	0.029	0.971
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.028	0.972
O62.9 Abnormality of forces of labour, unspecified	0.027	0.972
O62.8 Other abnormalities of forces of labour	0.027	0.972
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.027	0.972
O62.3 Precipitate labour	0.027	0.972
O62.1 Secondary uterine inertia	0.027	0.972
O62.0 Primary inadequate contractions	0.027	0.972
Chapter XV Pregnancy, childbirth and the puerperium	0.027	0.973
M06.9 Rheumatoid arthritis, unspecified	0.027	0.973
O60.3 Preterm delivery without spontaneous labour	0.025	0.974
O60.2 Preterm spontaneous labour with term delivery	0.025	0.974
O60.1 Preterm spontaneous labour with preterm delivery	0.025	0.974
O60.0 Preterm labour without delivery	0.025	0.974
O61.9 Failed induction of labour, unspecified	0.025	0.974
O61.8 Other failed induction of labour	0.025	0.974
O61.1 Failed instrumental induction of labour	0.025	0.974
O61.0 Failed medical induction of labour	0.025	0.974
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.025	0.974
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.025	0.974
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.025	0.974
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.025	0.974
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.025	0.974
O65.2 Obstructed labour due to pelvic inlet contraction	0.025	0.974
O65.1 Obstructed labour due to generally contracted pelvis	0.025	0.974
O65.0 Obstructed labour due to deformed pelvis	0.025	0.974
O67.9 Intrapartum haemorrhage, unspecified	0.025	0.974
O67.8 Other intrapartum haemorrhage	0.025	0.974
O67.0 Intrapartum haemorrhage with coagulation defect	0.025	0.974
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.025	0.974
O74.8 Other complications of anaesthesia during labour and delivery	0.025	0.974
O74.7 Failed or difficult intubation during labour and delivery	0.025	0.974
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.025	0.974
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.025	0.974
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.025	0.974
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.025	0.974
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.025	0.974
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.025	0.974
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.025	0.974
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.025	0.975
O64.8 Obstructed labour due to other malposition and malpresentation	0.025	0.975
O64.5 Obstructed labour due to compound presentation	0.025	0.975
O64.4 Obstructed labour due to shoulder presentation	0.025	0.975
O64.3 Obstructed labour due to brow presentation	0.025	0.975
O64.2 Obstructed labour due to face presentation	0.025	0.975
O64.1 Obstructed labour due to breech presentation	0.025	0.975
O69.1 Labour and delivery complicated by cord around neck, with compression	0.025	0.975
O69.9 Labour and delivery complicated by cord complication, unspecified	0.024	0.975
O69.8 Labour and delivery complicated by other cord complications	0.024	0.975
O69.5 Labour and delivery complicated by vascular lesion of cord	0.024	0.975
O69.4 Labour and delivery complicated by vasa praevia	0.024	0.975
O69.3 Labour and delivery complicated by short cord	0.024	0.975
O69.0 Labour and delivery complicated by prolapse of cord	0.024	0.975
M06 Other rheumatoid arthritis	0.024	0.976
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.024	0.976
O75.2 Pyrexia during labour, not elsewhere classified	0.024	0.976
O70.2 Third degree perineal laceration during delivery	0.023	0.976
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.023	0.977
O70.9 Perineal laceration during delivery, unspecified	0.023	0.977
O70.3 Fourth degree perineal laceration during delivery	0.023	0.977
O85-O92 Complications predominantly related to the puerperium	0.023	0.977
O75.9 Complication of labour and delivery, unspecified	0.022	0.977
O75.8 Other specified complications of labour and delivery	0.022	0.977
O75.5 Delayed delivery after artificial rupture of membranes	0.022	0.977
O75.4 Other complications of obstetric surgery and procedures	0.022	0.977
O75.3 Other infection during labour	0.022	0.977
O75.1 Shock during or following labour and delivery	0.022	0.977
O75.0 Maternal distress during labour and delivery	0.022	0.977
M06.0 Seronegative rheumatoid arthritis	0.022	0.978
O69.2 Labour and delivery complicated by other cord entanglement	0.022	0.978
O70.1 Second degree perineal laceration during delivery	0.022	0.978
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.022	0.978
O72.3 Postpartum coagulation defects	0.021	0.978
O72.1 Other immediate postpartum haemorrhage	0.021	0.979
O75.7 Vaginal delivery following previous Caesarean section	0.021	0.979
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.021	0.979
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.021	0.979
O70.0 First degree perineal laceration during delivery	0.020	0.980
O00-O08 Pregnancy with abortive outcome	0.020	0.980
M06.3 Rheumatoid nodule	0.020	0.980
O36 Maternal care for other known or suspected foetal problems	0.020	0.980
O86 Other puerperal infections	0.020	0.980
O72.2 Delayed and secondary postpartum haemorrhage	0.020	0.980
M06.98 Rheumatoid arthritis, unspecified (Other)	0.020	0.980
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.020	0.980
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.020	0.980
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.020	0.980
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.020	0.980
T81.4 Infection following a procedure, not elsewhere classified	0.019	0.981
O36.8 Maternal care for other specified foetal problems	0.019	0.981
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.019	0.981
M06.4 Inflammatory polyarthropathy	0.019	0.981
O72.0 Third-stage haemorrhage	0.019	0.981
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.018	0.981
S40-S49 Injuries to the shoulder and upper arm	0.019	0.981
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.018	0.981
O20-O29 Other maternal disorders predominantly related to pregnancy	0.018	0.981
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.018	0.982
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.018	0.982
E05.0 Thyrotoxicosis with diffuse goitre	0.018	0.982
O42 Premature rupture of membranes	0.018	0.982
O94-O99 Other obstetric conditions, not elsewhere classified	0.018	0.982
M06.8 Other specified rheumatoid arthritis	0.018	0.982
M06.2 Rheumatoid bursitis	0.018	0.982
M06.1 Adult-onset Still's disease	0.018	0.982
O02 Other abnormal products of conception	0.018	0.982
S42 Fracture of shoulder and upper arm	0.018	0.982
T81 Complications of procedures, not elsewhere classified	0.018	0.982
E05 Thyrotoxicosis [hyperthyroidism]	0.018	0.982
E05.9 Thyrotoxicosis, unspecified	0.018	0.982
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.017	0.983
M06.37 Rheumatoid nodule (Ankle and foot)	0.017	0.983
O80-O84 Delivery	0.017	0.983
T90 Sequelae of injuries of head	0.017	0.983
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.017	0.983
O92 Other disorders of breast and lactation associated with childbirth	0.017	0.983
O91 Infections of breast associated with childbirth	0.017	0.983
O90 Complications of the puerperium, not elsewhere classified	0.017	0.983
O89 Complications of anaesthesia during the puerperium	0.017	0.983
O88 Obstetric embolism	0.017	0.983
O87 Venous complications in the puerperium	0.017	0.983
O85 Puerperal sepsis	0.017	0.983
O47 False labour	0.017	0.983
O43 Placental disorders	0.017	0.983
O86.4 Pyrexia of unknown origin following delivery	0.016	0.983
O86.0 Infection of obstetric surgical wound	0.016	0.984
M06.08 Seronegative rheumatoid arthritis (Other)	0.016	0.984
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.016	0.984
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.016	0.984
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.016	0.984
M06.04 Seronegative rheumatoid arthritis (Hand)	0.016	0.984
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.016	0.984
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.016	0.984
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.016	0.984
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.016	0.984
S42.1 Fracture of scapula	0.016	0.984
S70-S79 Injuries to the hip and thigh	0.016	0.984
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.016	0.984
O02.1 Missed abortion	0.016	0.984
O42.9 Premature rupture of membranes, unspecified	0.016	0.984
O45 Premature separation of placenta [abruptio placentae]	0.016	0.984
O44 Placenta praevia	0.016	0.984
O35 Maternal care for known or suspected foetal abnormality and damage	0.016	0.984
O33 Maternal care for known or suspected disproportion	0.016	0.984
O31 Complications specific to multiple gestation	0.016	0.984
O40 Polyhydramnios	0.016	0.984
C18 Malignant neoplasm of colon	0.016	0.984
O41 Other disorders of amniotic fluid and membranes	0.016	0.984
O48 Prolonged pregnancy	0.016	0.984
S42.10 Fracture of scapula (closed)	0.015	0.985
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.015	0.985
S46 Injury of muscle and tendon at shoulder and upper arm level	0.015	0.985
Z72.0 Tobacco use	0.015	0.985
T90.9 Sequelae of unspecified injury of head	0.015	0.985
T81.3 Disruption of operation wound, not elsewhere classified	0.015	0.985
S20-S29 Injuries to the thorax	0.015	0.985
S50-S59 Injuries to the elbow and forearm	0.015	0.985
S49 Other and unspecified injuries of shoulder and upper arm	0.015	0.985
C18.5 Splenic flexure	0.015	0.985
O08 Complications following abortion and ectopic and molar pregnancy	0.014	0.985
O07 Failed attempted abortion	0.014	0.985
O06 Unspecified abortion	0.014	0.985
O05 Other abortion	0.014	0.985
O01 Hydatidiform mole	0.014	0.985
O00 Ectopic pregnancy	0.014	0.985
M06.39 Rheumatoid nodule (Site unspecified)	0.014	0.985
M06.38 Rheumatoid nodule (Other)	0.014	0.985
M06.36 Rheumatoid nodule (Lower leg)	0.014	0.985
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.014	0.985
M06.34 Rheumatoid nodule (Hand)	0.014	0.985
M06.33 Rheumatoid nodule (Forearm)	0.014	0.985
M06.32 Rheumatoid nodule (Upper arm)	0.014	0.985
M06.31 Rheumatoid nodule (Shoulder region)	0.014	0.985
M06.30 Rheumatoid nodule (Multiple sites)	0.014	0.985
O46 Antepartum haemorrhage, not elsewhere classified	0.014	0.985
O36.9 Maternal care for foetal problem, unspecified	0.014	0.985
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.014	0.985
O36.6 Maternal care for excessive foetal growth	0.014	0.985
O36.4 Maternal care for intra-uterine death	0.014	0.985
O36.3 Maternal care for signs of foetal hypoxia	0.014	0.985
O36.2 Maternal care for hydrops foetalis	0.014	0.985
O36.1 Maternal care for other isoimmunisation	0.014	0.985
O86.8 Other specified puerperal infections	0.014	0.985
O86.3 Other genito-urinary tract infections following delivery	0.014	0.985
O86.2 Urinary tract infection following delivery	0.014	0.985
O86.1 Other infection of genital tract following delivery	0.014	0.985
O30 Multiple gestation	0.014	0.986
S42.9 Fracture of shoulder girdle, part unspecified	0.014	0.986
C18.6 Descending colon	0.014	0.986
T81.8 Other complications of procedures, not elsewhere classified	0.014	0.986
T90.2 Sequelae of fracture of skull and facial bones	0.014	0.986
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.014	0.986
S42.2 Fracture of upper end of humerus	0.014	0.986
T79-T79 Certain early complications of trauma	0.014	0.986
S10-S19 Injuries to the neck	0.014	0.986
T66-T78 Other and unspecified effects of external causes	0.014	0.986
O23 Infections of genito-urinary tract in pregnancy	0.014	0.986
S72 Fracture of femur	0.014	0.986
T88 Other complications of surgical and medical care, not elsewhere classified	0.014	0.986
M06.48 Inflammatory polyarthropathy (Other)	0.014	0.986
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.014	0.986
M06.46 Inflammatory polyarthropathy (Lower leg)	0.014	0.986
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.014	0.986
M06.44 Inflammatory polyarthropathy (Hand)	0.014	0.986
M06.43 Inflammatory polyarthropathy (Forearm)	0.014	0.986
M06.42 Inflammatory polyarthropathy (Upper arm)	0.014	0.986
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.014	0.986
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.014	0.986
C18.7 Sigmoid colon	0.014	0.986
T90.4 Sequelae of injury of eye and orbit	0.014	0.986
O24 Diabetes mellitus in pregnancy	0.014	0.986
O36.0 Maternal care for rhesus isoimmunisation	0.014	0.986
T92 Sequelae of injuries of upper limb	0.014	0.986
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.014	0.986
S43.1 Dislocation of acromioclavicular joint	0.014	0.986
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.014	0.986
S48 Traumatic amputation of shoulder and upper arm	0.014	0.986
S45 Injury of blood vessels at shoulder and upper arm level	0.014	0.986
S44 Injury of nerves at shoulder and upper arm level	0.014	0.986
S41 Open wound of shoulder and upper arm	0.014	0.986
S47 Crushing injury of shoulder and upper arm	0.014	0.986
O36.5 Maternal care for poor foetal growth	0.013	0.986
O21 Excessive vomiting in pregnancy	0.013	0.986
T98 Sequelae of other and unspecified effects of external causes	0.014	0.986
C18.9 Colon, unspecified	0.014	0.986
O29 Complications of anaesthesia during pregnancy	0.013	0.986
O28 Abnormal findings on antenatal screening of mother	0.013	0.986
O22 Venous complications in pregnancy	0.013	0.986
O25 Malnutrition in pregnancy	0.013	0.986
O47.1 False labour at or after 37 completed weeks of gestation	0.013	0.987
O32 Maternal care for known or suspected malpresentation of foetus	0.013	0.987
S22 Fracture of rib(s), sternum and thoracic spine	0.013	0.987
O15 Eclampsia	0.013	0.987
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.013	0.987
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.013	0.987
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.013	0.987
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.013	0.987
T33-T35 Frostbite	0.013	0.987
T26-T28 Burns and corrosions confined to eye and internal organs	0.013	0.987
T20-T25 Burns and corrosions of external body surface, specified by site	0.013	0.987
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.013	0.987
T00-T07 Injuries involving multiple body regions	0.013	0.987
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.013	0.987
O42.2 Premature rupture of membranes, labour delayed by therapy	0.013	0.987
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.013	0.987
O97 Death from sequelae of direct obstetric causes	0.013	0.987
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.013	0.987
O95 Obstetric death of unspecified cause	0.013	0.987
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.013	0.987
S70 Superficial injury of hip and thigh	0.013	0.987
O16 Unspecified maternal hypertension	0.013	0.987
S40 Superficial injury of shoulder and upper arm	0.013	0.987
T85 Complications of other internal prosthetic devices, implants and grafts	0.013	0.987
S80-S89 Injuries to the knee and lower leg	0.013	0.987
M06.19 Adult-onset Still's disease (Site unspecified)	0.013	0.987
M06.18 Adult-onset Still's disease (Other)	0.013	0.987
M06.17 Adult-onset Still's disease (Ankle and foot)	0.013	0.987
M06.16 Adult-onset Still's disease (Lower leg)	0.013	0.987
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.013	0.987
M06.14 Adult-onset Still's disease (Hand)	0.013	0.987
M06.13 Adult-onset Still's disease (Forearm)	0.013	0.987
M06.12 Adult-onset Still's disease (Upper arm)	0.013	0.987
M06.11 Adult-onset Still's disease (Shoulder region)	0.013	0.987
M06.10 Adult-onset Still's disease (Multiple sites)	0.013	0.987
M06.29 Rheumatoid bursitis (Site unspecified)	0.013	0.987
M06.28 Rheumatoid bursitis (Other)	0.013	0.987
M06.27 Rheumatoid bursitis (Ankle and foot)	0.013	0.987
M06.26 Rheumatoid bursitis (Lower leg)	0.013	0.987
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.013	0.987
M06.24 Rheumatoid bursitis (Hand)	0.013	0.987
M06.23 Rheumatoid bursitis (Forearm)	0.013	0.987
M06.22 Rheumatoid bursitis (Upper arm)	0.013	0.987
M06.21 Rheumatoid bursitis (Shoulder region)	0.013	0.987
M06.20 Rheumatoid bursitis (Multiple sites)	0.013	0.987
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.013	0.987
M06.88 Other specified rheumatoid arthritis (Other)	0.013	0.987
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.013	0.987
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.013	0.987
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.013	0.987
M06.84 Other specified rheumatoid arthritis (Hand)	0.013	0.987
M06.83 Other specified rheumatoid arthritis (Forearm)	0.013	0.987
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.013	0.987
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.013	0.987
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.013	0.987
T15-T19 Effects of foreign body entering through natural orifice	0.013	0.987
O02.9 Abnormal product of conception, unspecified	0.013	0.987
O02.8 Other specified abnormal products of conception	0.013	0.987
O02.0 Blighted ovum and nonhydatidiform mole	0.013	0.987
S46.0 Injury of tendon of the rotator cuff of shoulder	0.013	0.987
O43.8 Other placental disorders	0.013	0.987
S42.8 Fracture of other parts of shoulder and upper arm	0.013	0.987
S42.7 Multiple fractures of clavicle, scapula and humerus	0.013	0.987
S42.4 Fracture of lower end of humerus	0.013	0.987
T81.9 Unspecified complication of procedure	0.013	0.987
T81.7 Vascular complications following a procedure, not elsewhere classified	0.013	0.987
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.013	0.987
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.013	0.987
E05.8 Other thyrotoxicosis	0.013	0.987
E05.5 Thyroid crisis or storm	0.013	0.987
E05.4 Thyrotoxicosis factitia	0.013	0.987
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.013	0.987
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.013	0.987
T95 Sequelae of burns, corrosions and frostbite	0.013	0.987
T94 Sequelae of injuries involving multiple and unspecified body regions	0.013	0.987
T91 Sequelae of injuries of neck and trunk	0.013	0.987
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.013	0.987
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.013	0.987
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.013	0.987
S42.3 Fracture of shaft of humerus	0.013	0.987
O04 Medical abortion	0.013	0.987
S90-S99 Injuries to the ankle and foot	0.013	0.987
S60-S69 Injuries to the wrist and hand	0.013	0.987
S43.0 Dislocation of shoulder joint	0.013	0.987
O26 Maternal care for other conditions predominantly related to pregnancy	0.013	0.987
O34 Maternal care for known or suspected abnormality of pelvic organs	0.012	0.987
C18.1 Appendix	0.013	0.987
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.012	0.987
C18.2 Ascending colon	0.012	0.987
M05-M14 Inflammatory polyarthropathies	0.012	0.987
O84 Multiple delivery	0.012	0.988
O83 Other assisted single delivery	0.012	0.988
O81 Single delivery by forceps and vacuum extractor	0.012	0.988
T90.8 Sequelae of other specified injuries of head	0.012	0.988
T90.5 Sequelae of intracranial injury	0.012	0.988
T90.3 Sequelae of injury of cranial nerves	0.012	0.988
T90.1 Sequelae of open wound of head	0.012	0.988
T90.0 Sequelae of superficial injury of head	0.012	0.988
O82 Single delivery by Caesarean section	0.012	0.988
C18.0 Caecum	0.012	0.988
O47.9 False labour, unspecified	0.012	0.988
T87 Complications peculiar to reattachment and amputation	0.012	0.988
T86 Failure and rejection of transplanted organs and tissues	0.012	0.988
T80 Complications following infusion, transfusion and therapeutic injection	0.012	0.988
O87.9 Venous complication in the puerperium, unspecified	0.012	0.988
O87.8 Other venous complications in the puerperium	0.012	0.988
O87.3 Cerebral venous thrombosis in the puerperium	0.012	0.988
O87.2 Haemorrhoids in the puerperium	0.012	0.988
O87.1 Deep phlebothrombosis in the puerperium	0.012	0.988
O87.0 Superficial thrombophlebitis in the puerperium	0.012	0.988
O88.8 Other obstetric embolism	0.012	0.988
O88.3 Obstetric pyaemic and septic embolism	0.012	0.988
O88.2 Obstetric blood-clot embolism	0.012	0.988
O88.1 Amniotic fluid embolism	0.012	0.988
O88.0 Obstetric air embolism	0.012	0.988
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.012	0.988
O89.8 Other complications of anaesthesia during the puerperium	0.012	0.988
O89.6 Failed or difficult intubation during the puerperium	0.012	0.988
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.012	0.988
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.012	0.988
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.012	0.988
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.012	0.988
O89.1 Cardiac complications of anaesthesia during the puerperium	0.012	0.988
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.012	0.988
O90.9 Complication of the puerperium, unspecified	0.012	0.988
O90.8 Other complications of the puerperium, not elsewhere classified	0.012	0.988
O90.5 Postpartum thyroiditis	0.012	0.988
O90.4 Postpartum acute renal failure	0.012	0.988
O90.3 Cardiomyopathy in the puerperium	0.012	0.988
O90.2 Haematoma of obstetric wound	0.012	0.988
O90.1 Disruption of perineal obstetric wound	0.012	0.988
O90.0 Disruption of Caesarean section wound	0.012	0.988
O91.2 Nonpurulent mastitis associated with childbirth	0.012	0.988
O91.1 Abscess of breast associated with childbirth	0.012	0.988
O91.0 Infection of nipple associated with childbirth	0.012	0.988
O92.7 Other and unspecified disorders of lactation	0.012	0.988
O92.6 Galactorrhoea	0.012	0.988
O92.5 Suppressed lactation	0.012	0.988
O92.4 Hypogalactia	0.012	0.988
O92.3 Agalactia	0.012	0.988
O92.2 Other and unspecified disorders of breast associated with childbirth	0.012	0.988
O92.1 Cracked nipple associated with childbirth	0.012	0.988
O92.0 Retracted nipple associated with childbirth	0.012	0.988
O43.9 Placental disorder, unspecified	0.012	0.988
O43.2 Morbidly adherent placenta	0.012	0.988
O43.1 Malformation of placenta	0.012	0.988
O43.0 Placental transfusion syndromes	0.012	0.988
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.012	0.988
S22.0 Fracture of thoracic vertebra	0.012	0.988
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.012	0.988
S72.1 Pertrochanteric fracture	0.012	0.988
O20 Haemorrhage in early pregnancy	0.012	0.988
E00-E07 Disorders of thyroid gland	0.012	0.988
O03 Spontaneous abortion	0.012	0.988
S42.11 Fracture of scapula (open)	0.012	0.988
H35 Other retinal disorders	0.012	0.988
M35.3 Polymyalgia rheumatica	0.012	0.988
S49.9 Unspecified injury of shoulder and upper arm	0.012	0.988
S50 Superficial injury of forearm	0.012	0.988
S78 Traumatic amputation of hip and thigh	0.012	0.988
S77 Crushing injury of hip and thigh	0.012	0.988
S76 Injury of muscle and tendon at hip and thigh level	0.012	0.988
S75 Injury of blood vessels at hip and thigh level	0.012	0.988
S74 Injury of nerves at hip and thigh level	0.012	0.988
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.012	0.988
S71 Open wound of hip and thigh	0.012	0.988
C18.4 Transverse colon	0.012	0.988
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.012	0.988
S43.6 Sprain and strain of sternoclavicular joint	0.012	0.988
S43.5 Sprain and strain of acromioclavicular joint	0.012	0.988
S43.4 Sprain and strain of shoulder joint	0.012	0.988
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.012	0.988
S43.2 Dislocation of sternoclavicular joint	0.012	0.988
S42.0 Fracture of clavicle	0.012	0.988
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.012	0.988
O31.8 Other complications specific to multiple gestation	0.011	0.988
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.011	0.988
O31.1 Continuing pregnancy after abortion of one foetus or more	0.011	0.988
O31.0 Papyraceous foetus	0.011	0.988
O33.9 Maternal care for disproportion, unspecified	0.011	0.988
O33.8 Maternal care for disproportion of other origin	0.011	0.988
O33.7 Maternal care for disproportion due to other foetal deformities	0.011	0.988
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.011	0.988
O33.5 Maternal care for disproportion due to unusually large foetus	0.011	0.988
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.011	0.988
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.011	0.988
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.011	0.988
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.011	0.988
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.011	0.988
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.011	0.988
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.011	0.988
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.011	0.988
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.011	0.988
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.011	0.988
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.011	0.988
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.011	0.988
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.011	0.988
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.011	0.988
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.011	0.988
O44.1 Placenta praevia with haemorrhage	0.011	0.988
O44.0 Placenta praevia specified as without haemorrhage	0.011	0.988
O45.9 Premature separation of placenta, unspecified	0.011	0.988
O45.8 Other premature separation of placenta	0.011	0.988
O45.0 Premature separation of placenta with coagulation defect	0.011	0.988
S62 Fracture at wrist and hand level	0.012	0.988
C18.8 Overlapping lesion of colon	0.012	0.988
C18.3 Hepatic flexure	0.012	0.988
S42.20 Fracture of upper end of humerus (closed)	0.012	0.988
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.012	0.988
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.011	0.988
O41.8 Other specified disorders of amniotic fluid and membranes	0.011	0.988
O41.1 Infection of amniotic sac and membranes	0.011	0.988
H35.3 Degeneration of macula and posterior pole	0.012	0.988
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.011	0.988
S79 Other and unspecified injuries of hip and thigh	0.011	0.988
T85.4 Mechanical complication of breast prosthesis and implant	0.011	0.989
O47.0 False labour before 37 completed weeks of gestation	0.011	0.989
S82 Fracture of lower leg, including ankle	0.011	0.989
T93 Sequelae of injuries of lower limb	0.011	0.989
O41.0 Oligohydramnios	0.011	0.989
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.011	0.989
S22.00 Fracture of thoracic vertebra (closed)	0.011	0.989
H30-H36 Disorders of choroid and retina	0.011	0.989
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.011	0.989

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations