TreeWAS – Variant ID: rs742132

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.270	0.730
K90 Intestinal malabsorption	0.000	0.771	0.229
E83 Disorders of mineral metabolism	0.000	0.806	0.194
K90.8 Other intestinal malabsorption	0.000	0.830	0.170
K90.3 Pancreatic steatorrhoea	0.000	0.836	0.164
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.836	0.164
K90.1 Tropical sprue	0.000	0.836	0.164
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.837	0.163
E83.4 Disorders of magnesium metabolism	0.000	0.840	0.160
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.861	0.139
E83.8 Other disorders of mineral metabolism	0.000	0.861	0.139
E83.2 Disorders of zinc metabolism	0.000	0.861	0.139
E83.0 Disorders of copper metabolism	0.000	0.861	0.139
K90.9 Intestinal malabsorption, unspecified	0.000	0.887	0.113
E83.3 Disorders of phosphorus metabolism	0.000	0.900	0.100
E83.5 Disorders of calcium metabolism	0.000	0.960	0.040
K90-K93 Other diseases of the digestive system	0.000	0.987	0.013
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.990	0.010
Z29.1 Prophylactic immunotherapy	0.009	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.009	0.991	0.000
E27 Other disorders of adrenal gland	0.009	0.991	0.000
E27.2 Addisonian crisis	0.009	0.991	0.000
Z29 Need for other prophylactic measures	0.008	0.992	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.008	0.992	0.000
E29.1 Testicular hypofunction	0.008	0.992	0.000
Z29.0 Isolation	0.008	0.992	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.993	0.007
K93.1 Megacolon in Chagas' disease	0.000	0.993	0.007
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.993	0.007
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.007	0.993	0.000
T93.2 Sequelae of other fractures of lower limb	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
E27.5 Adrenomedullary hyperfunction	0.006	0.993	0.000
E27.0 Other adrenocortical overactivity	0.006	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.994	0.006
Z29.2 Other prophylactic chemotherapy	0.006	0.994	0.000
Z29.8 Other specified prophylactic measures	0.006	0.994	0.000
E20 Hypoparathyroidism	0.006	0.994	0.000
D37.5 Rectum	0.006	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.994	0.000
Z29.9 Prophylactic measure, unspecified	0.006	0.994	0.000
F40.2 Specific (isolated) phobias	0.005	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
E34 Other endocrine disorders	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
E24 Cushing's syndrome	0.005	0.995	0.000
M65.34 Trigger finger-Hand	0.000	0.995	0.005
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.005	0.995	0.000
S92.30 Fracture of metatarsal bone (closed)	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.004	0.995	0.000
H53.1 Subjective visual disturbances	0.005	0.995	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.004	0.996	0.000
F40 Phobic anxiety disorders	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
F40.9 Phobic anxiety disorder, unspecified	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
E22.8 Other hyperfunction of pituitary gland	0.004	0.996	0.000
E28 Ovarian dysfunction	0.004	0.996	0.000
C18.2 Ascending colon	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
F40.1 Social phobias	0.004	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
F40.0 Agoraphobia	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.996	0.000
T93 Sequelae of injuries of lower limb	0.004	0.996	0.000
F40.8 Other phobic anxiety disorders	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
R45.1 Restlessness and agitation	0.003	0.997	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.997	0.001
Q38.7 Pharyngeal pouch	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.997	0.000
R45 Symptoms and signs involving emotional state	0.003	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.003	0.997	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.003	0.997	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
R45.7 State of emotional shock and stress, unspecified	0.003	0.997	0.000
X49.9 Unspecified place	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
Z26 Need for immunisation against other single infectious diseases	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.002	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
R45.4 Irritability and anger	0.002	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
M05.8 Other seropositive rheumatoid arthritis	0.002	0.997	0.000
T93.1 Sequelae of fracture of femur	0.002	0.997	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M06.9 Rheumatoid arthritis, unspecified	0.002	0.998	0.000
Z28 Immunisation not carried out	0.002	0.998	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.002	0.998	0.000
Z25 Need for immunisation against other single viral diseases	0.002	0.998	0.000
Z24 Need for immunisation against certain single viral diseases	0.002	0.998	0.000
Z23 Need for immunisation against single bacterial diseases	0.002	0.998	0.000
Z20 Contact with and exposure to communicable diseases	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
R45.2 Unhappiness	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.000	0.998	0.002
R45.5 Hostility	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
R40.0 Somnolence	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.998	0.002
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.001
R45.0 Nervousness	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
D18.0 Haemangioma, any site	0.000	0.998	0.002
D37.1 Stomach	0.002	0.998	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.002	0.998	0.000
R45.3 Demoralisation and apathy	0.002	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
M65.3 Trigger finger	0.000	0.998	0.002
N36.0 Urethral fistula	0.002	0.998	0.000
Z22.8 Carrier of other infectious diseases	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.002	0.998	0.000
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
X49.6 Industrial and construction area	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.002	0.998	0.000
Z26.0 Need for immunisation against leishmaniasis	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
X41.9 Unspecified place	0.002	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
C25.3 Pancreatic duct	0.000	0.998	0.002
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.000	0.998	0.002
Z20.9 Contact with and exposure to unspecified communicable disease	0.002	0.998	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.002	0.998	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.002	0.998	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.002	0.998	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.002	0.998	0.000
Z20.4 Contact with and exposure to rubella	0.002	0.998	0.000
Z20.3 Contact with and exposure to rabies	0.002	0.998	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
Z20.1 Contact with and exposure to tuberculosis	0.002	0.998	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.002	0.998	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.002	0.998	0.000
Z23.7 Need for immunisation against pertussis alone	0.002	0.998	0.000
Z23.6 Need for immunisation against diphtheria alone	0.002	0.998	0.000
Z23.5 Need for immunisation against tetanus alone	0.002	0.998	0.000
Z23.4 Need for immunisation against tularaemia	0.002	0.998	0.000
Z23.3 Need for immunisation against plague	0.002	0.998	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.002	0.998	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.002	0.998	0.000
Z23.0 Need for immunisation against cholera alone	0.002	0.998	0.000
Z24.6 Need for immunisation against viral hepatitis	0.002	0.998	0.000
Z24.5 Need for immunisation against rubella alone	0.002	0.998	0.000
Z24.4 Need for immunisation against measles alone	0.002	0.998	0.000
Z24.3 Need for immunisation against yellow fever	0.002	0.998	0.000
Z24.2 Need for immunisation against rabies	0.002	0.998	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.002	0.998	0.000
Z24.0 Need for immunisation against poliomyelitis	0.002	0.998	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.002	0.998	0.000
Z25.1 Need for immunisation against influenza	0.002	0.998	0.000
Z25.0 Need for immunisation against mumps alone	0.002	0.998	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.002	0.998	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.002	0.998	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.002	0.998	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.002	0.998	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.002	0.998	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.002	0.998	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.002	0.998	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.002	0.998	0.000
Z28.8 Immunisation not carried out for other reasons	0.002	0.998	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.002	0.998	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.002	0.998	0.000
Z28.0 Immunisation not carried out because of contraindication	0.002	0.998	0.000
Z22 Carrier of infectious disease	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
I77.1 Stricture of artery	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.002	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
Z74.0 Reduced mobility	0.000	0.998	0.002
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.998	0.002
M54.44 Lumbago with sciatica-Thoracic	0.000	0.998	0.002
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.998	0.002
M54.42 Lumbago with sciatica-Cervical	0.000	0.998	0.002
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.998	0.002
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.998	0.002
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
G35 Multiple sclerosis	0.000	0.998	0.002
D23.7 Skin of lower limb, including hip	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
R45.6 Physical violence	0.002	0.998	0.000
X49.4 Street and highway	0.002	0.998	0.000
X49.0 Home	0.002	0.998	0.000
X49.8 Other specified place	0.002	0.998	0.000
X49.7 Farm	0.002	0.998	0.000
X49.5 Trade and service area	0.002	0.998	0.000
X49.3 Sports and athletics area	0.002	0.998	0.000
X49.2 School, other institution and public administrative area	0.002	0.998	0.000
X49.1 Residential institution	0.002	0.998	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
R40.2 Coma, unspecified	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.000	0.998	0.002
M65.38 Trigger finger-Other	0.000	0.998	0.002
M65.37 Trigger finger-Ankle/foot	0.000	0.998	0.002
M65.36 Trigger finger-Lower leg	0.000	0.998	0.002
M65.35 Trigger finger-Pelvic/thigh	0.000	0.998	0.002
M65.33 Trigger finger-Forearm	0.000	0.998	0.002
M65.32 Trigger finger-Upper arm	0.000	0.998	0.002
M65.31 Trigger finger-Shldr region	0.000	0.998	0.002
M65.30 Trigger finger-Mult sites	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.002	0.998	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.002	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.002	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.002	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.002	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.002	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.002	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.002	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.002	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.998	0.000
M05.08 Felty's syndrome (Other)	0.002	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.998	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.998	0.000
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.998	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.998	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
C18.5 Splenic flexure	0.000	0.998	0.002
C25.0 Head of pancreas	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
M06 Other rheumatoid arthritis	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.002	0.998	0.000
C25.1 Body of pancreas	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Z22.9 Carrier of infectious disease, unspecified	0.002	0.998	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.002	0.998	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
Z22.2 Carrier of diphtheria	0.002	0.998	0.000
Z22.0 Carrier of typhoid	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.002	0.998	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
X40-X49 Accidental poisoning by and exposure to noxious substances	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
C50.0 Nipple and areola	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.001	0.998	0.000
M21.28 Flexion deformity (Other)	0.001	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.998	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.001	0.998	0.000
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.001	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
O80.0 Spontaneous vertex delivery	0.000	0.998	0.002
L05 Pilonidal cyst	0.002	0.998	0.000
R40.1 Stupor	0.002	0.998	0.000
X41.0 Home	0.001	0.998	0.000
X41.8 Other specified place	0.001	0.998	0.000
X41.7 Farm	0.001	0.998	0.000
X41.6 Industrial and construction area	0.001	0.998	0.000
X41.5 Trade and service area	0.001	0.998	0.000
X41.4 Street and highway	0.001	0.998	0.000
X41.3 Sports and athletics area	0.001	0.998	0.000
X41.2 School, other institution and public administrative area	0.001	0.998	0.000
X41.1 Residential institution	0.001	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.001
M06.8 Other specified rheumatoid arthritis	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.998	0.001
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.998	0.000
C25.2 Tail of pancreas	0.000	0.998	0.001
M21.9 Acquired deformity of limb, unspecified	0.001	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.001	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.001	0.998	0.000
Z58.4 Exposure to radiation	0.001	0.998	0.000
Z58.3 Exposure to soil pollution	0.001	0.998	0.000
Z58.2 Exposure to water pollution	0.001	0.998	0.000
Z58.0 Exposure to noise	0.001	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.998	0.000
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
X45 Accidental poisoning by and exposure to alcohol	0.001	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.001
C25.7 Other parts of pancreas	0.000	0.998	0.001
M77.92 Enthesopathy, unspecified (Upper arm)	0.001	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.001	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.998	0.000
D37.3 Appendix	0.001	0.998	0.000
M06.2 Rheumatoid bursitis	0.001	0.998	0.000
M06.1 Adult-onset Still's disease	0.001	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.998	0.002
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.001	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.001	0.998	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.001	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.001	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.001	0.998	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.001	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
X45.0 Home	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations