TreeWAS – Variant ID: rs7429990

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H92.1 Otorrhoea	0.157	0.843	0.000
H92 Otalgia and effusion of ear	0.155	0.845	0.000
H90-H95 Other disorders of ear	0.144	0.856	0.000
H92.0 Otalgia	0.141	0.859	0.000
H90 Conductive and sensorineural hearing loss	0.137	0.863	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.131	0.869	0.000
H93 Other disorders of ear, not elsewhere classified	0.129	0.871	0.000
H90.5 Sensorineural hearing loss, unspecified	0.117	0.883	0.000
H92.2 Otorrhagia	0.115	0.885	0.000
H90.2 Conductive hearing loss, unspecified	0.113	0.887	0.000
H93.1 Tinnitus	0.109	0.891	0.000
H90.0 Conductive hearing loss, bilateral	0.107	0.893	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.104	0.896	0.000
H93.9 Disorder of ear, unspecified	0.101	0.899	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.098	0.902	0.000
H93.8 Other specified disorders of ear	0.096	0.903	0.000
H93.3 Disorders of acoustic nerve	0.096	0.904	0.000
H90.3 Sensorineural hearing loss, bilateral	0.096	0.904	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.095	0.905	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.095	0.905	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.094	0.906	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.094	0.906	0.000
H93.2 Other abnormal auditory perceptions	0.094	0.906	0.000
Chapter VIII Diseases of the ear and mastoid process	0.093	0.907	0.000
H93.0 Degenerative and vascular disorders of ear	0.092	0.907	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.091	0.909	0.000
H65-H75 Diseases of middle ear and mastoid	0.090	0.910	0.000
H66 Suppurative and unspecified otitis media	0.087	0.913	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.085	0.915	0.000
H66.3 Other chronic suppurative otitis media	0.082	0.918	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.082	0.918	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.082	0.918	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.081	0.918	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.081	0.919	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.081	0.919	0.000
T43.2 Other and unspecified antidepressants	0.081	0.919	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.081	0.919	0.000
T46.1 Calcium-channel blockers	0.081	0.919	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.080	0.920	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.077	0.923	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.077	0.923	0.000
H72 Perforation of tympanic membrane	0.077	0.923	0.000
H70 Mastoiditis and related conditions	0.076	0.924	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.075	0.925	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.075	0.925	0.000
H72.0 Central perforation of tympanic membrane	0.075	0.925	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.075	0.925	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.074	0.925	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.074	0.925	0.000
H71 Cholesteatoma of middle ear	0.075	0.925	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.074	0.926	0.000
H95.1 Other disorders following mastoidectomy	0.074	0.926	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.073	0.927	0.000
H91 Other hearing loss	0.073	0.927	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.072	0.928	0.000
H66.9 Otitis media, unspecified	0.071	0.929	0.000
H74 Other disorders of middle ear and mastoid	0.071	0.929	0.000
T36 Poisoning by systemic antibiotics	0.070	0.929	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.070	0.929	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.070	0.929	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.070	0.930	0.000
T38.1 Thyroid hormones and substitutes	0.070	0.930	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.068	0.932	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.068	0.932	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.068	0.932	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.068	0.932	0.000
T42.0 Hydantoin derivatives	0.068	0.932	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.067	0.932	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.067	0.932	0.000
T46.7 Peripheral vasodilators	0.067	0.932	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.067	0.932	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.067	0.932	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.067	0.933	0.000
T40.4 Other synthetic narcotics	0.067	0.933	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.067	0.933	0.000
T40.2 Other opioids	0.066	0.934	0.000
T43.9 Psychotropic drug, unspecified	0.066	0.934	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.066	0.934	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.066	0.934	0.000
H60-H62 Diseases of external ear	0.065	0.935	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.065	0.935	0.000
T42.3 Barbiturates	0.065	0.935	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.065	0.935	0.000
H68 Eustachian salpingitis and obstruction	0.065	0.935	0.000
H67 Otitis media in diseases classified elsewhere	0.065	0.935	0.000
H73 Other disorders of tympanic membrane	0.064	0.936	0.000
H70.8 Other mastoiditis and related conditions	0.063	0.937	0.000
H66.0 Acute suppurative otitis media	0.062	0.937	0.000
T47.2 Stimulant laxatives	0.062	0.938	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.062	0.938	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.062	0.938	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.061	0.939	0.000
T47.0 Histamine H(2)-receptor antagonists	0.061	0.939	0.000
T42.1 Iminostilbenes	0.060	0.940	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.059	0.941	0.000
H72.8 Other perforations of tympanic membrane	0.059	0.941	0.000
T40.6 Other and unspecified narcotics	0.059	0.941	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.059	0.941	0.000
T42.2 Succinimides and oxazolidinediones	0.059	0.941	0.000
H70.9 Mastoiditis, unspecified	0.059	0.941	0.000
H66.4 Suppurative otitis media, unspecified	0.059	0.941	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.059	0.941	0.000
H72.1 Attic perforation of tympanic membrane	0.058	0.942	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.058	0.942	0.000
T40.8 Lysergide [LSD]	0.058	0.942	0.000
T40.7 Cannabis (derivatives)	0.058	0.942	0.000
T40.5 Cocaine	0.058	0.942	0.000
T40.3 Methadone	0.058	0.942	0.000
T40.1 Heroin	0.058	0.942	0.000
T40.0 Opium	0.058	0.942	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.058	0.942	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.058	0.942	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.058	0.942	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.057	0.942	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.057	0.942	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.057	0.942	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.057	0.942	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.057	0.942	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.057	0.942	0.000
T44.0 Anticholinesterase agents	0.057	0.942	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.057	0.943	0.000
H91.3 Deaf mutism, not elsewhere classified	0.057	0.943	0.000
H74.4 Polyp of middle ear	0.057	0.943	0.000
H91.8 Other specified hearing loss	0.056	0.943	0.000
H60 Otitis externa	0.057	0.943	0.000
T38.9 Other and unspecified hormone antagonists	0.055	0.944	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.055	0.944	0.000
T38.7 Androgens and anabolic congeners	0.055	0.944	0.000
T38.5 Other oestrogens and progestogens	0.055	0.944	0.000
T38.4 Oral contraceptives	0.055	0.944	0.000
T38.2 Antithyroid drugs	0.055	0.944	0.000
T38.0 Glucocorticoids and synthetic analogues	0.055	0.944	0.000
T43.6 Psychostimulants with abuse potential	0.055	0.945	0.000
H70.1 Chronic mastoiditis	0.054	0.945	0.000
H70.2 Petrositis	0.054	0.945	0.000
H70.0 Acute mastoiditis	0.054	0.945	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.054	0.945	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.054	0.946	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.054	0.946	0.000
T47.7 Emetics	0.054	0.946	0.000
T47.6 Antidiarrhoeal drugs	0.054	0.946	0.000
T47.5 Digestants	0.054	0.946	0.000
T47.4 Other laxatives	0.054	0.946	0.000
T47.3 Saline and osmotic laxatives	0.054	0.946	0.000
T50.7 Analeptics and opioid receptor antagonists	0.054	0.946	0.000
T50.5 Appetite depressants	0.054	0.946	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.054	0.946	0.000
T50.1 Loop [high-ceiling] diuretics	0.054	0.946	0.000
T50.0 Mineralocorticoids and their antagonists	0.054	0.946	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.053	0.946	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.053	0.947	0.000
T36.3 Macrolides	0.053	0.947	0.000
H91.0 Ototoxic hearing loss	0.052	0.947	0.000
H91.2 Sudden idiopathic hearing loss	0.052	0.948	0.000
H73.1 Chronic myringitis	0.052	0.948	0.000
T36.0 Penicillins	0.051	0.948	0.000
T36.9 Systemic antibiotic, unspecified	0.051	0.949	0.000
T36.8 Other systemic antibiotics	0.051	0.949	0.000
T36.7 Antifungal antibiotics, systemically used	0.051	0.949	0.000
T36.6 Rifamycins	0.051	0.949	0.000
T36.5 Aminoglycosides	0.051	0.949	0.000
T36.4 Tetracyclines	0.051	0.949	0.000
T36.2 Chloramphenicol group	0.051	0.949	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.051	0.949	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.051	0.949	0.000
T37.5 Antiviral drugs	0.051	0.949	0.000
T37.4 Anthelminthics	0.051	0.949	0.000
T37.3 Other antiprotozoal drugs	0.051	0.949	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.051	0.949	0.000
T37.1 Antimycobacterial drugs	0.051	0.949	0.000
T37.0 Sulphonamides	0.051	0.949	0.000
T50.8 Diagnostic agents	0.051	0.949	0.000
T50.4 Drugs affecting uric acid metabolism	0.051	0.949	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.050	0.949	0.000
T48.5 Anti-common-cold drugs	0.050	0.949	0.000
T48.4 Expectorants	0.050	0.949	0.000
T48.3 Antitussives	0.050	0.949	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.050	0.949	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.050	0.949	0.000
T48.0 Oxytocic drugs	0.050	0.949	0.000
H74.1 Adhesive middle ear disease	0.050	0.950	0.000
T41.5 Therapeutic gases	0.049	0.951	0.000
T41.4 Anaesthetic, unspecified	0.049	0.951	0.000
T41.3 Local anaesthetics	0.049	0.951	0.000
T41.2 Other and unspecified general anaesthetics	0.049	0.951	0.000
T41.1 Intravenous anaesthetics	0.049	0.951	0.000
T41.0 Inhaled anaesthetics	0.049	0.951	0.000
T49.9 Topical agent, unspecified	0.049	0.951	0.000
T49.8 Other topical agents	0.049	0.951	0.000
T49.7 Dental drugs, topically applied	0.049	0.951	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.049	0.951	0.000
T49.5 Ophthalmological drugs and preparations	0.049	0.951	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.049	0.951	0.000
T49.3 Emollients, demulcents and protectants	0.049	0.951	0.000
T49.2 Local astringents and local detergents	0.049	0.951	0.000
T49.1 Antipruritics	0.049	0.951	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.049	0.951	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.049	0.951	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.048	0.952	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.047	0.952	0.000
H91.1 Presbycusis	0.047	0.953	0.000
H60.9 Otitis externa, unspecified	0.047	0.953	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.047	0.953	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.047	0.953	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.047	0.953	0.000
H68.1 Obstruction of Eustachian tube	0.047	0.953	0.000
H68.0 Eustachian salpingitis	0.047	0.953	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.047	0.953	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.047	0.953	0.000
T45.2 Vitamins, not elsewhere classified	0.046	0.954	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.046	0.954	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.046	0.954	0.000
H73.0 Acute myringitis	0.046	0.954	0.000
H60.8 Other otitis externa	0.046	0.954	0.000
H60.5 Acute otitis externa, non-infective	0.044	0.955	0.000
H60.1 Cellulitis of external ear	0.044	0.956	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.042	0.958	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.042	0.958	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.042	0.958	0.000
T45.8 Other primarily systemic and haematological agents	0.042	0.958	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.042	0.958	0.000
T45.6 Fibrinolysis-affecting drugs	0.042	0.958	0.000
T45.4 Iron and its compounds	0.042	0.958	0.000
T45.3 Enzymes, not elsewhere classified	0.042	0.958	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.041	0.959	0.000
H60.2 Malignant otitis externa	0.041	0.959	0.000
H69 Other disorders of Eustachian tube	0.040	0.960	0.000
H74.0 Tympanosclerosis	0.040	0.960	0.000
H72.2 Other marginal perforations of tympanic membrane	0.039	0.961	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.039	0.961	0.000
H60.0 Abscess of external ear	0.039	0.961	0.000
H60.4 Cholesteatoma of external ear	0.038	0.962	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.037	0.963	0.000
H60.3 Other infective otitis externa	0.036	0.963	0.000
E87.0 Hyperosmolality and hypernatraemia	0.035	0.965	0.000
T45.0 Antiallergic and antiemetic drugs	0.035	0.965	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.033	0.966	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.033	0.966	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.033	0.966	0.000
H62.2 Otitis externa in mycoses	0.033	0.966	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.033	0.966	0.000
T45.5 Anticoagulants	0.033	0.967	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.032	0.967	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.032	0.968	0.000
H80-H83 Diseases of inner ear	0.032	0.968	0.000
E53.8 Deficiency of other specified B group vitamins	0.032	0.968	0.000
H73.8 Other specified disorders of tympanic membrane	0.031	0.969	0.000
H69.0 Patulous Eustachian tube	0.029	0.971	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.029	0.971	0.000
E87.3 Alkalosis	0.028	0.972	0.000
E53 Deficiency of other B group vitamins	0.027	0.973	0.000
H61 Other disorders of external ear	0.027	0.973	0.000
H65 Nonsuppurative otitis media	0.026	0.974	0.000
E87.6 Hypokalaemia	0.025	0.975	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.024	0.976	0.000
E87.7 Fluid overload	0.024	0.976	0.000
H61.3 Acquired stenosis of external ear canal	0.024	0.976	0.000
E87.4 Mixed disorder of acid-base balance	0.023	0.977	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.023	0.977	0.000
E53.9 Vitamin B deficiency, unspecified	0.022	0.977	0.000
E50-E64 Other nutritional deficiencies	0.022	0.978	0.000
H81 Disorders of vestibular function	0.022	0.978	0.000
H69.9 Eustachian tube disorder, unspecified	0.021	0.979	0.000
E70-E90 Metabolic disorders	0.021	0.979	0.000
E88 Other metabolic disorders	0.021	0.979	0.000
H61.8 Other specified disorders of external ear	0.020	0.979	0.000
T42.4 Benzodiazepines	0.020	0.980	0.000
H65.4 Other chronic nonsuppurative otitis media	0.020	0.980	0.000
E53.1 Pyridoxine deficiency	0.020	0.980	0.000
E53.0 Riboflavin deficiency	0.020	0.980	0.000
E06.3 Autoimmune thyroiditis	0.020	0.980	0.000
H65.2 Chronic serous otitis media	0.020	0.980	0.000
H81.8 Other disorders of vestibular function	0.019	0.981	0.000
H69.8 Other specified disorders of Eustachian tube	0.018	0.981	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.018	0.981	0.000
E06 Thyroiditis	0.018	0.982	0.000
H61.1 Non-infective disorders of pinna	0.018	0.982	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.018	0.982	0.000
E88.9 Metabolic disorder, unspecified	0.018	0.982	0.000
T39.4 Antirheumatics, not elsewhere classified	0.018	0.982	0.000
T39.2 Pyrazolone derivatives	0.018	0.982	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.018	0.982	0.000
E58 Dietary calcium deficiency	0.018	0.982	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.018	0.982	0.000
H65.1 Other acute nonsuppurative otitis media	0.017	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.017	0.983	0.000
H81.2 Vestibular neuronitis	0.017	0.983	0.000
E86 Volume depletion	0.017	0.983	0.000
E61 Deficiency of other nutrient elements	0.016	0.983	0.000
E85 Amyloidosis	0.017	0.983	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.017	0.983	0.000
E56 Other vitamin deficiencies	0.016	0.984	0.000
H65.0 Acute serous otitis media	0.016	0.984	0.000
E00-E07 Disorders of thyroid gland	0.016	0.984	0.000
H61.9 Disorder of external ear, unspecified	0.016	0.984	0.000
E83 Disorders of mineral metabolism	0.016	0.984	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.016	0.984	0.000
E63 Other nutritional deficiencies	0.016	0.984	0.000
E50 Vitamin A deficiency	0.016	0.984	0.000
E60 Dietary zinc deficiency	0.016	0.984	0.000
E59 Dietary selenium deficiency	0.016	0.984	0.000
E54 Ascorbic acid deficiency	0.016	0.984	0.000
E52 Niacin deficiency [pellagra]	0.016	0.984	0.000
E88.2 Lipomatosis, not elsewhere classified	0.016	0.984	0.000
E79 Disorders of purine and pyrimidine metabolism	0.016	0.984	0.000
H81.4 Vertigo of central origin	0.016	0.984	0.000
E72 Other disorders of amino-acid metabolism	0.016	0.984	0.000
H81.1 Benign paroxysmal vertigo	0.016	0.984	0.000
E74 Other disorders of carbohydrate metabolism	0.015	0.984	0.000
E88.3 Tumour lysis syndrome	0.015	0.984	0.000
H80 Otosclerosis	0.015	0.985	0.001
E77 Disorders of glycoprotein metabolism	0.015	0.985	0.000
E76 Disorders of glycosaminoglycan metabolism	0.015	0.985	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.015	0.985	0.000
E70 Disorders of aromatic amino-acid metabolism	0.015	0.985	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.015	0.985	0.000
E06.9 Thyroiditis, unspecified	0.015	0.985	0.000
E51 Thiamine deficiency	0.015	0.985	0.000
E88.8 Other specified metabolic disorders	0.015	0.985	0.000
E83.5 Disorders of calcium metabolism	0.015	0.985	0.000
H81.9 Disorder of vestibular function, unspecified	0.015	0.985	0.000
E84 Cystic fibrosis	0.015	0.985	0.000
E07 Other disorders of thyroid	0.015	0.985	0.000
E61.2 Magnesium deficiency	0.014	0.986	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.014	0.986	0.000
E83.4 Disorders of magnesium metabolism	0.014	0.986	0.000
E55 Vitamin D deficiency	0.014	0.986	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.014	0.986	0.000
E07.9 Disorder of thyroid, unspecified	0.014	0.986	0.000
E06.5 Other chronic thyroiditis	0.014	0.986	0.000
H65.3 Chronic mucoid otitis media	0.014	0.986	0.000
E06.4 Drug-induced thyroiditis	0.013	0.987	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.013	0.987	0.000
E06.1 Subacute thyroiditis	0.013	0.987	0.000
E06.0 Acute thyroiditis	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
H61.2 Impacted cerumen	0.013	0.987	0.000
E85.9 Amyloidosis, unspecified	0.013	0.987	0.000
E56.1 Deficiency of vitamin K	0.013	0.987	0.000
H81.3 Other peripheral vertigo	0.012	0.987	0.000
H83 Other diseases of inner ear	0.012	0.988	0.000
E85.3 Secondary systemic amyloidosis	0.012	0.988	0.000
E85.4 Organ-limited amyloidosis	0.012	0.988	0.000
E85.8 Other amyloidosis	0.012	0.988	0.000
E61.9 Deficiency of nutrient element, unspecified	0.012	0.988	0.000
E61.8 Deficiency of other specified nutrient elements	0.012	0.988	0.000
E61.7 Deficiency of multiple nutrient elements	0.012	0.988	0.000
E61.6 Vanadium deficiency	0.012	0.988	0.000
E61.5 Molybdenum deficiency	0.012	0.988	0.000
E61.4 Chromium deficiency	0.012	0.988	0.000
E61.3 Manganese deficiency	0.012	0.988	0.000
E61.0 Copper deficiency	0.012	0.988	0.000
E74.0 Glycogen storage disease	0.012	0.988	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.012	0.988	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.012	0.988	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.012	0.988	0.000
E56.9 Vitamin deficiency, unspecified	0.012	0.988	0.000
E56.8 Deficiency of other vitamins	0.012	0.988	0.000
E56.0 Deficiency of vitamin E	0.012	0.988	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.012	0.988	0.000
E00 Congenital iodine-deficiency syndrome	0.012	0.988	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.012	0.988	0.000
E73 Lactose intolerance	0.012	0.988	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.012	0.988	0.000
E72.0 Disorders of amino-acid transport	0.012	0.988	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.012	0.988	0.000
E83.8 Other disorders of mineral metabolism	0.012	0.988	0.000
E83.2 Disorders of zinc metabolism	0.012	0.988	0.000
E83.0 Disorders of copper metabolism	0.012	0.988	0.000
E50.9 Vitamin A deficiency, unspecified	0.011	0.988	0.000
E50.8 Other manifestations of vitamin A deficiency	0.011	0.988	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.011	0.988	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.011	0.988	0.000
E50.5 Vitamin A deficiency with night blindness	0.011	0.988	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.011	0.988	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.011	0.988	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.011	0.988	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.011	0.988	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.011	0.988	0.000
E63.9 Nutritional deficiency, unspecified	0.011	0.988	0.000
E63.8 Other specified nutritional deficiencies	0.011	0.988	0.000
E63.1 Imbalance of constituents of food intake	0.011	0.988	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.011	0.988	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.011	0.988	0.000
E64.8 Sequelae of other nutritional deficiencies	0.011	0.988	0.000
E64.3 Sequelae of rickets	0.011	0.988	0.000
E64.2 Sequelae of vitamin C deficiency	0.011	0.988	0.000
E64.1 Sequelae of vitamin A deficiency	0.011	0.988	0.000
E64.0 Sequelae of protein-energy malnutrition	0.011	0.988	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.011	0.988	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.011	0.988	0.000
E79.1 Lesch-Nyhan syndrome	0.011	0.988	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.011	0.988	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.011	0.988	0.000
E72.5 Disorders of glycine metabolism	0.011	0.988	0.000
E72.4 Disorders of ornithine metabolism	0.011	0.988	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.011	0.988	0.000
E72.2 Disorders of urea cycle metabolism	0.011	0.988	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.011	0.988	0.000
E40-E46 Malnutrition	0.011	0.989	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.011	0.989	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.011	0.989	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.011	0.989	0.000
E74.2 Disorders of galactose metabolism	0.011	0.989	0.000
E74.1 Disorders of fructose metabolism	0.011	0.989	0.000
H81.0 Meniere's disease	0.011	0.989	0.000
H80.8 Other otosclerosis	0.011	0.989	0.001
H80.2 Cochlear otosclerosis	0.011	0.989	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.011	0.989	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.011	0.989	0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.011	0.989	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.011	0.989	0.000
E70.3 Albinism	0.011	0.989	0.000
E70.2 Disorders of tyrosine metabolism	0.011	0.989	0.000
E70.1 Other hyperphenylalaninaemias	0.011	0.989	0.000
E70.0 Classical phenylketonuria	0.011	0.989	0.000
E71.3 Disorders of fatty-acid metabolism	0.011	0.989	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.011	0.989	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.011	0.989	0.000
E71.0 Maple-syrup-urine disease	0.011	0.989	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.011	0.989	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.011	0.989	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.011	0.989	0.000
E76.2 Other mucopolysaccharidoses	0.011	0.989	0.000
E76.1 Mucopolysaccharidosis, type II	0.011	0.989	0.000
E76.0 Mucopolysaccharidosis, type I	0.011	0.989	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.011	0.989	0.000
E77.8 Other disorders of glycoprotein metabolism	0.011	0.989	0.000
E77.1 Defects in glycoprotein degradation	0.011	0.989	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.011	0.989	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.011	0.989	0.000
E51.9 Thiamine deficiency, unspecified	0.011	0.989	0.000
E51.8 Other manifestations of thiamine deficiency	0.011	0.989	0.000
E51.1 Beriberi	0.011	0.989	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.011	0.989	0.000
E03 Other hypothyroidism	0.011	0.989	0.000
E84.8 Cystic fibrosis with other manifestations	0.011	0.989	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.011	0.989	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.011	0.989	0.000
T39.0 Salicylates	0.011	0.989	0.000
E07.1 Dyshormogenetic goitre	0.011	0.989	0.000
E07.0 Hypersecretion of calcitonin	0.011	0.989	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.011	0.989	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.989	0.011
E51.2 Wernicke's encephalopathy	0.010	0.989	0.000
E75.6 Lipid storage disorder, unspecified	0.010	0.990	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.010	0.990	0.000
E75.3 Sphingolipidosis, unspecified	0.010	0.990	0.000
E75.2 Other sphingolipidosis	0.010	0.990	0.000
E75.1 Other gangliosidosis	0.010	0.990	0.000
E75.0 GM2 gangliosidosis	0.010	0.990	0.000
E55.0 Rickets, active	0.010	0.990	0.000
E84.9 Cystic fibrosis, unspecified	0.010	0.990	0.000
E03.8 Other specified hypothyroidism	0.010	0.990	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.010	0.990	0.000
E07.8 Other specified disorders of thyroid	0.009	0.991	0.000
H83.9 Disease of inner ear, unspecified	0.009	0.991	0.000
E75.5 Other lipid storage disorders	0.009	0.991	0.000
H83.3 Noise effects on inner ear	0.009	0.991	0.000
H83.2 Labyrinthine dysfunction	0.009	0.991	0.000
H83.1 Labyrinthine fistula	0.009	0.991	0.000
E80.1 Porphyria cutanea tarda	0.009	0.991	0.000
E61.1 Iron deficiency	0.009	0.991	0.000
X60-X84 Intentional self-harm	0.009	0.991	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.009	0.991	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.009	0.991	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.009	0.991	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.009	0.991	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.009	0.991	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.009	0.991	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.009	0.991	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.009	0.991	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.009	0.991	0.000
E80.5 Crigler-Najjar syndrome	0.009	0.991	0.000
E80.3 Defects of catalase and peroxydase	0.009	0.991	0.000
E80.0 Hereditary erythropoietic porphyria	0.009	0.991	0.000
E73.8 Other lactose intolerance	0.009	0.991	0.000
E73.1 Secondary lactase deficiency	0.009	0.991	0.000
E73.0 Congenital lactase deficiency	0.009	0.991	0.000
E80.2 Other porphyria	0.008	0.991	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.009	0.991	0.000
E89.2 Postprocedural hypoparathyroidism	0.009	0.991	0.000
E55.9 Vitamin D deficiency, unspecified	0.009	0.991	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.009	0.991	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.008	0.992	0.000
E45 Retarded development following protein-energy malnutrition	0.008	0.992	0.000
E43 Unspecified severe protein-energy malnutrition	0.008	0.992	0.000
E42 Marasmic kwashiorkor	0.008	0.992	0.000
E41 Nutritional marasmus	0.008	0.992	0.000
E40 Kwashiorkor	0.008	0.992	0.000
M25.53 Pain in joint (Forearm)	0.008	0.992	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.008	0.992	0.000
H91.9 Hearing loss, unspecified	0.008	0.992	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.008	0.992	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.008	0.992	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.008	0.992	0.000
E89.5 Postprocedural testicular hypofunction	0.008	0.992	0.000
E89.1 Postprocedural hypoinsulinaemia	0.008	0.992	0.000
E03.1 Congenital hypothyroidism without goitre	0.008	0.992	0.000
E03.5 Myxoedema coma	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations