TreeWAS – Variant ID: rs74335365

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I30-I52 Other forms of heart disease	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I50 Heart failure	1.000	0.000
I50.0 Congestive heart failure	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J30-J39 Other diseases of upper respiratory tract	0.999	0.001
J33 Nasal polyp	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010
I44 Atrioventricular and left bundle-branch block	0.988	0.012
Chapter IV Endocrine, nutritional and metabolic diseases	0.987	0.013
J33.0 Polyp of nasal cavity	0.987	0.013
I95-I99 Other and unspecified disorders of the circulatory system	0.983	0.017
L00-L08 Infections of the skin and subcutaneous tissue	0.982	0.018
I44.2 Atrioventricular block, complete	0.972	0.028
L03 Cellulitis	0.963	0.037
N17-N19 Renal failure	0.962	0.038
E20-E35 Disorders of other endocrine glands	0.960	0.040
N18 Chronic renal failure	0.958	0.042
I44.7 Left bundle-branch block, unspecified	0.956	0.044
Chapter XIV Diseases of the genitourinary system	0.953	0.047
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.949	0.051
N17 Acute renal failure	0.943	0.057
I50.9 Heart failure, unspecified	0.937	0.063
J09-J18 Influenza and pneumonia	0.937	0.063
I99 Other and unspecified disorders of circulatory system	0.937	0.063
I49 Other cardiac arrhythmias	0.934	0.066
J33.8 Other polyp of sinus	0.931	0.069
E65-E68 Obesity and other hyperalimentation	0.929	0.071
N17.9 Acute renal failure, unspecified	0.928	0.072
L03.1 Cellulitis of other parts of limb	0.927	0.073
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.923	0.077
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.922	0.078
S90-S99 Injuries to the ankle and foot	0.921	0.079
J36 Peritonsillar abscess	0.920	0.080
J31.0 Chronic rhinitis	0.915	0.085
N18.5 Chronic kidney disease, stage 5	0.913	0.087
I34 Nonrheumatic mitral valve disorders	0.912	0.088
J40-J47 Chronic lower respiratory diseases	0.911	0.089
N18.4 Chronic kidney disease, stage 4	0.904	0.096
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.902	0.098
N18.9 Chronic renal failure, unspecified	0.901	0.099
I60-I69 Cerebrovascular diseases	0.901	0.099
L03.2 Cellulitis of face	0.894	0.106
T20-T25 Burns and corrosions of external body surface, specified by site	0.893	0.107
L50-L54 Urticaria and erythema	0.890	0.110
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.888	0.112
E66 Obesity	0.879	0.121
T51 Toxic effect of alcohol	0.878	0.122
J43 Emphysema	0.877	0.123
J20-J22 Other acute lower respiratory infections	0.872	0.128
J15 Bacterial pneumonia, not elsewhere classified	0.869	0.131
I42 Cardiomyopathy	0.868	0.132
E66.8 Other obesity	0.867	0.133
I34.0 Mitral (valve) insufficiency	0.863	0.137
E34 Other endocrine disorders	0.863	0.137
I51 Complications and ill-defined descriptions of heart disease	0.863	0.137
I30 Acute pericarditis	0.862	0.138
I70-I79 Diseases of arteries, arterioles and capillaries	0.862	0.138
K82.8 Other specified diseases of gallbladder	0.861	0.139
K82 Other diseases of gallbladder	0.859	0.141
J33.9 Nasal polyp, unspecified	0.859	0.141
S92 Fracture of foot, except ankle	0.857	0.143
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.856	0.144
J35 Chronic diseases of tonsils and adenoids	0.854	0.146
I82 Other venous embolism and thrombosis	0.854	0.146
T79-T79 Certain early complications of trauma	0.853	0.147
J43.9 Emphysema, unspecified	0.853	0.147
N19 Unspecified renal failure	0.847	0.153
I49.0 Ventricular fibrillation and flutter	0.847	0.153
K86 Other diseases of pancreas	0.847	0.153
T51.0 Ethanol	0.847	0.153
E22 Hyperfunction of pituitary gland	0.845	0.155
I51.8 Other ill-defined heart diseases	0.842	0.158
L53 Other erythematous conditions	0.842	0.158
L03.8 Cellulitis of other sites	0.842	0.158
N25-N29 Other disorders of kidney and ureter	0.839	0.161
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.837	0.163
I95 Hypotension	0.836	0.164
I82.8 Embolism and thrombosis of other specified veins	0.836	0.164
L02 Cutaneous abscess, furuncle and carbuncle	0.834	0.166
E23 Hypofunction and other disorders of pituitary gland	0.834	0.166
I47 Paroxysmal tachycardia	0.828	0.172
J18 Pneumonia, organism unspecified	0.827	0.173
Chapter XI Diseases of the digestive system	0.825	0.175
S60-S69 Injuries to the wrist and hand	0.821	0.179
I49.3 Ventricular premature depolarisation	0.818	0.182
N10-N16 Renal tubulo-interstitial diseases	0.817	0.183
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.817	0.183
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.816	0.184
I77 Other disorders of arteries and arterioles	0.815	0.185
E28 Ovarian dysfunction	0.811	0.189
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.809	0.191
J35.1 Hypertrophy of tonsils	0.808	0.192
L53.9 Erythematous condition, unspecified	0.808	0.192
J18.1 Lobar pneumonia, unspecified	0.807	0.193
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.804	0.196
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.804	0.196
S32 Fracture of lumbar spine and pelvis	0.803	0.197
S10-S19 Injuries to the neck	0.802	0.198
K35-K38 Diseases of appendix	0.798	0.202
E00-E07 Disorders of thyroid gland	0.796	0.204
J44 Other chronic obstructive pulmonary disease	0.794	0.206
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.793	0.207
S92.3 Fracture of metatarsal bone	0.790	0.210
I61 Intracerebral haemorrhage	0.789	0.211
K35 Acute appendicitis	0.779	0.221
K86.0 Alcohol-induced chronic pancreatitis	0.778	0.222
L08 Other local infections of skin and subcutaneous tissue	0.778	0.222
K35.0 Acute appendicitis with generalised peritonitis	0.774	0.226
I60 Subarachnoid haemorrhage	0.772	0.228
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.772	0.228
N00-N08 Glomerular diseases	0.771	0.229
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.770	0.230
K86.1 Other chronic pancreatitis	0.770	0.230
J37 Chronic laryngitis and laryngotracheitis	0.768	0.231
N13 Obstructive and reflux uropathy	0.769	0.231
E03 Other hypothyroidism	0.766	0.234
S31 Open wound of abdomen, lower back and pelvis	0.765	0.234
I63 Cerebral infarction	0.764	0.236
S62 Fracture at wrist and hand level	0.764	0.236
I80 Phlebitis and thrombophlebitis	0.764	0.236
I95.1 Orthostatic hypotension	0.763	0.237
E70-E90 Metabolic disorders	0.763	0.237
L03.0 Cellulitis of finger and toe	0.760	0.240
L05 Pilonidal cyst	0.760	0.240
E87 Other disorders of fluid, electrolyte and acid-base balance	0.758	0.242
I97.2 Postmastectomy lymphoedema syndrome	0.758	0.242
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.242
T79 Certain early complications of trauma, not elsewhere classified	0.752	0.248
I77.9 Disorder of arteries and arterioles, unspecified	0.748	0.252
S36 Injury of intra-abdominal organs	0.747	0.253
Chapter VIII Diseases of the ear and mastoid process	0.747	0.253
L10-L14 Bullous disorders	0.745	0.255
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.745	0.255
E87.6 Hypokalaemia	0.744	0.256
S92.30 Fracture of metatarsal bone (closed)	0.742	0.258
I77.1 Stricture of artery	0.739	0.261
N18.2 Chronic kidney disease, stage 2	0.739	0.261
I49.8 Other specified cardiac arrhythmias	0.737	0.263
E29 Testicular dysfunction	0.737	0.263
I73 Other peripheral vascular diseases	0.736	0.264
E34.9 Endocrine disorder, unspecified	0.735	0.265
N18.0 End-stage renal disease	0.735	0.265
L40-L45 Papulosquamous disorders	0.734	0.266
E87.7 Fluid overload	0.733	0.267
E34.0 Carcinoid syndrome	0.732	0.268
K86.8 Other specified diseases of pancreas	0.732	0.268
J17 Pneumonia in diseases classified elsewhere	0.732	0.268
I42.6 Alcoholic cardiomyopathy	0.731	0.269
E22.1 Hyperprolactinaemia	0.731	0.269
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.725	0.275
I70 Atherosclerosis	0.725	0.275
S60 Superficial injury of wrist and hand	0.724	0.276
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.724	0.276
J11 Influenza, virus not identified	0.723	0.277
T86 Failure and rejection of transplanted organs and tissues	0.723	0.277
J80-J84 Other respiratory diseases principally affecting the interstitium	0.721	0.279
J15.0 Pneumonia due to Klebsiella pneumoniae	0.718	0.282
I42.0 Dilated cardiomyopathy	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T66-T78 Other and unspecified effects of external causes	0.716	0.284
I47.1 Supraventricular tachycardia	0.715	0.285
J33.1 Polypoid sinus degeneration	0.715	0.285
I49.1 Atrial premature depolarisation	0.714	0.286
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S90 Superficial injury of ankle and foot	0.712	0.288
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.712	0.288
J30 Vasomotor and allergic rhinitis	0.712	0.288
K85 Acute pancreatitis	0.711	0.289
I98 Other disorders of circulatory system in diseases classified elsewhere	0.710	0.289
I30.1 Infective pericarditis	0.709	0.291
T56 Toxic effect of metals	0.709	0.291
I69 Sequelae of cerebrovascular disease	0.709	0.291
I44.5 Left posterior fascicular block	0.708	0.291
I44.4 Left anterior fascicular block	0.708	0.291
J00-J06 Acute upper respiratory infections	0.708	0.292
Q78 Other osteochondrodysplasias	0.708	0.292
Q50-Q56 Congenital malformations of genital organs	0.708	0.292
I63.9 Cerebral infarction, unspecified	0.707	0.293
E65 Localised adiposity	0.707	0.293
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.706	0.294
T20 Burn and corrosion of head and neck	0.706	0.294
J21 Acute bronchiolitis	0.706	0.294
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.705	0.295
Chapter XX External causes of morbidity and mortality	0.705	0.295
I30.9 Acute pericarditis, unspecified	0.705	0.295
T23 Burn and corrosion of wrist and hand	0.705	0.295
N18.8 Other chronic renal failure	0.704	0.296
I88 Nonspecific lymphadenitis	0.704	0.296
L04 Acute lymphadenitis	0.704	0.296
L01 Impetigo	0.704	0.296
L00 Staphylococcal scalded skin syndrome	0.704	0.296
K82.1 Hydrops of gallbladder	0.704	0.296
N28 Other disorders of kidney and ureter, not elsewhere classified	0.704	0.296
I89.1 Lymphangitis	0.704	0.296
J15.1 Pneumonia due to Pseudomonas	0.702	0.298
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.702	0.298
S32.7 Multiple fractures of lumbar spine and pelvis	0.701	0.299
J22 Unspecified acute lower respiratory infection	0.700	0.300
N17.0 Acute renal failure with tubular necrosis	0.699	0.301
I87 Other disorders of veins	0.699	0.301
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.699	0.301
T92 Sequelae of injuries of upper limb	0.699	0.301
E23.0 Hypopituitarism	0.698	0.302
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.697	0.303
I36 Nonrheumatic tricuspid valve disorders	0.693	0.307
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.692	0.307
E40-E46 Malnutrition	0.691	0.309
I37 Pulmonary valve disorders	0.691	0.309
K82.2 Perforation of gallbladder	0.690	0.310
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.690	0.310
I64 Stroke, not specified as haemorrhage or infarction	0.690	0.310
E27 Other disorders of adrenal gland	0.689	0.311
T59 Toxic effect of other gases, fumes and vapours	0.689	0.311
J60-J70 Lung diseases due to external agents	0.689	0.311
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.689	0.311
E35 Disorders of endocrine glands in diseases classified elsewhere	0.688	0.312
E32 Diseases of thymus	0.688	0.312
E31 Polyglandular dysfunction	0.688	0.312
E30 Disorders of puberty, not elsewhere classified	0.688	0.312
E25 Adrenogenital disorders	0.688	0.312
E20 Hypoparathyroidism	0.688	0.312
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.687	0.313
N18.1 Chronic kidney disease, stage 1	0.687	0.313
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.687	0.313
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.686	0.314
S92.2 Fracture of other tarsal bone(s)	0.686	0.314
K86.9 Disease of pancreas, unspecified	0.685	0.315
I34.2 Nonrheumatic mitral (valve) stenosis	0.684	0.316
E28.2 Polycystic ovarian syndrome	0.683	0.317
J15.5 Pneumonia due to Escherichia coli	0.683	0.317
K37 Unspecified appendicitis	0.682	0.318
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.680	0.319
J31.1 Chronic nasopharyngitis	0.680	0.320
J40 Bronchitis, not specified as acute or chronic	0.680	0.320
J20 Acute bronchitis	0.677	0.323
J15.4 Pneumonia due to other streptococci	0.677	0.323
E23.2 Diabetes insipidus	0.676	0.324
N17.8 Other acute renal failure	0.676	0.324
N17.2 Acute renal failure with medullary necrosis	0.676	0.324
N17.1 Acute renal failure with acute cortical necrosis	0.676	0.324
S66 Injury of muscle and tendon at wrist and hand level	0.676	0.324
S80-S89 Injuries to the knee and lower leg	0.676	0.324
Q38-Q45 Other congenital malformations of the digestive system	0.675	0.325
N26 Unspecified contracted kidney	0.674	0.326
I49.9 Cardiac arrhythmia, unspecified	0.674	0.326
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.673	0.327
I42.8 Other cardiomyopathies	0.673	0.327
K82.4 Cholesterolosis of gallbladder	0.672	0.328
N13.9 Obstructive and reflux uropathy, unspecified	0.672	0.328
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.672	0.328
J12 Viral pneumonia, not elsewhere classified	0.672	0.328
J09 Influenza due to certain identified influenza virus	0.672	0.328
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.672	0.328
E03.8 Other specified hypothyroidism	0.671	0.329
E03.9 Hypothyroidism, unspecified	0.670	0.330
I49.2 Junctional premature depolarisation	0.669	0.331
J39 Other diseases of upper respiratory tract	0.668	0.332
I60.9 Subarachnoid haemorrhage, unspecified	0.667	0.333
E24 Cushing's syndrome	0.666	0.334
E67 Other hyperalimentation	0.666	0.334
E68 Sequelae of hyperalimentation	0.666	0.334
E26 Hyperaldosteronism	0.666	0.334
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.665	0.335
I42.1 Obstructive hypertrophic cardiomyopathy	0.664	0.336
J44.8 Other specified chronic obstructive pulmonary disease	0.664	0.336
T79.7 Traumatic subcutaneous emphysema	0.663	0.337
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.662	0.338
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.662	0.338
T65 Toxic effect of other and unspecified substances	0.662	0.338
T62 Toxic effect of other noxious substances eaten as food	0.662	0.338
T61 Toxic effect of noxious substances eaten as seafood	0.662	0.338
T60 Toxic effect of pesticides	0.662	0.338
T57 Toxic effect of other inorganic substances	0.662	0.338
T54 Toxic effect of corrosive substances	0.662	0.338
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.662	0.338
T52 Toxic effect of organic solvents	0.662	0.338
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.662	0.338
T55 Toxic effect of soaps and detergents	0.662	0.338
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.661	0.339
S37 Injury of urinary and pelvic organs	0.661	0.339
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.661	0.339
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.661	0.339
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.661	0.339
S98 Traumatic amputation of ankle and foot	0.660	0.339
S97 Crushing injury of ankle and foot	0.660	0.339
S96 Injury of muscle and tendon at ankle and foot level	0.660	0.339
S95 Injury of blood vessels at ankle and foot level	0.660	0.339
S94 Injury of nerves at ankle and foot level	0.660	0.339
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.659	0.341
S32.3 Fracture of ilium	0.659	0.341
T21 Burn and corrosion of trunk	0.658	0.341
J31.2 Chronic pharyngitis	0.658	0.342
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.657	0.343
I31 Other diseases of pericardium	0.656	0.344
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.656	0.344
S91 Open wound of ankle and foot	0.656	0.344
L20-L30 Dermatitis and eczema	0.655	0.345
I34.8 Other nonrheumatic mitral valve disorders	0.654	0.346
J41 Simple and mucopurulent chronic bronchitis	0.653	0.347
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.652	0.348
H65-H75 Diseases of middle ear and mastoid	0.650	0.350
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.648	0.352
N13.4 Hydroureter	0.648	0.352
J00 Acute nasopharyngitis [common cold]	0.647	0.352
S10 Superficial injury of neck	0.647	0.353
S62.7 Multiple fractures of fingers	0.647	0.353
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.646	0.353
Q35-Q37 Cleft lip and cleft palate	0.646	0.353
Q30-Q34 Congenital malformations of the respiratory system	0.646	0.353
I68 Cerebrovascular disorders in diseases classified elsewhere	0.646	0.354
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.646	0.354
T58 Toxic effect of carbon monoxide	0.644	0.356
I61.8 Other intracerebral haemorrhage	0.643	0.357
S70-S79 Injuries to the hip and thigh	0.643	0.357
S20-S29 Injuries to the thorax	0.642	0.358
L80-L99 Other disorders of the skin and subcutaneous tissue	0.641	0.359
I46 Cardiac arrest	0.641	0.359
T25 Burn and corrosion of ankle and foot	0.640	0.360
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.639	0.361
S31.1 Open wound of abdominal wall	0.639	0.361
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.639	0.361
T15-T19 Effects of foreign body entering through natural orifice	0.639	0.361
L54 Erythema in diseases classified elsewhere	0.638	0.362
L51 Erythema multiforme	0.638	0.362
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.638	0.362
N13.3 Other and unspecified hydronephrosis	0.637	0.363
S92.4 Fracture of great toe	0.636	0.364
T82.0 Mechanical complication of heart valve prosthesis	0.634	0.366
S62.2 Fracture of first metacarpal bone	0.633	0.366
J42 Unspecified chronic bronchitis	0.632	0.368
N25 Disorders resulting from impaired renal tubular function	0.632	0.368
S32.4 Fracture of acetabulum	0.632	0.368
D68 Other coagulation defects	0.631	0.369
N05 Unspecified nephritic syndrome	0.631	0.369
T86.1 Kidney transplant failure and rejection	0.631	0.369
Q78.0 Osteogenesis imperfecta	0.630	0.370
E66.1 Drug-induced obesity	0.630	0.370
E66.0 Obesity due to excess calories	0.630	0.370
Q12 Congenital lens malformations	0.630	0.370
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.630	0.370
I73.0 Raynaud's syndrome	0.630	0.370
K86.2 Cyst of pancreas	0.630	0.370
I44.6 Other and unspecified fascicular block	0.629	0.370
T51.8 Other alcohols	0.629	0.371
T51.3 Fusel oil	0.629	0.371
T51.2 2-Propanol	0.629	0.371
T51.1 Methanol	0.629	0.371
J43.8 Other emphysema	0.629	0.371
J43.2 Centrilobular emphysema	0.629	0.371
J43.1 Panlobular emphysema	0.629	0.371
J43.0 MacLeod's syndrome	0.629	0.371
S92.1 Fracture of talus	0.628	0.372
E66.2 Extreme obesity with alveolar hypoventilation	0.628	0.372
I95.8 Other hypotension	0.627	0.372
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.627	0.373
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.627	0.373
I60.8 Other subarachnoid haemorrhage	0.627	0.373
L52 Erythema nodosum	0.626	0.374
I95.2 Hypotension due to drugs	0.626	0.374
J15.9 Bacterial pneumonia, unspecified	0.623	0.377
J15.8 Other bacterial pneumonia	0.623	0.377
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.623	0.377
J15.3 Pneumonia due to streptococcus, group B	0.623	0.377
S62.4 Multiple fractures of metacarpal bones	0.622	0.378
I42.7 Cardiomyopathy due to drugs and other external agents	0.622	0.378
I42.5 Other restrictive cardiomyopathy	0.622	0.378
I42.4 Endocardial fibroelastosis	0.622	0.378
I42.3 Endomyocardial (eosinophilic) disease	0.622	0.378
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.622	0.378
I70.2 Atherosclerosis of arteries of the extremities	0.622	0.378
S62.0 Fracture of navicular [scaphoid] bone of hand	0.622	0.378
Q80-Q89 Other congenital malformations	0.621	0.379
N04 Nephrotic syndrome	0.621	0.379
S80 Superficial injury of lower leg	0.621	0.379
E28.3 Primary ovarian failure	0.620	0.380
T92.1 Sequelae of fracture of arm	0.620	0.380
T51.9 Alcohol, unspecified	0.620	0.380
S60.9 Superficial injury of wrist and hand, unspecified	0.619	0.381
Q76 Congenital malformations of spine and bony thorax	0.619	0.381
E85 Amyloidosis	0.619	0.381
E34.8 Other specified endocrine disorders	0.619	0.381
E34.5 Androgen resistance syndrome	0.619	0.381
E34.4 Constitutional tall stature	0.619	0.381
E34.3 Short stature, not elsewhere classified	0.619	0.381
E34.2 Ectopic hormone secretion, not elsewhere classified	0.619	0.381
E34.1 Other hypersecretion of intestinal hormones	0.619	0.381
I77.0 Arteriovenous fistula, acquired	0.619	0.381
I51.5 Myocardial degeneration	0.619	0.381
I51.3 Intracardiac thrombosis, not elsewhere classified	0.619	0.381
I51.2 Rupture of papillary muscle, not elsewhere classified	0.619	0.381
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.619	0.381
J10 Influenza due to identified influenza virus	0.619	0.381
I30.8 Other forms of acute pericarditis	0.618	0.382
I30.0 Acute nonspecific idiopathic pericarditis	0.618	0.382
I87.1 Compression of vein	0.618	0.382
S99 Other and unspecified injuries of ankle and foot	0.618	0.382
I45 Other conduction disorders	0.618	0.382
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.618	0.382
I47.9 Paroxysmal tachycardia, unspecified	0.617	0.382
I61.5 Intracerebral haemorrhage, intraventricular	0.617	0.383
K82.3 Fistula of gallbladder	0.616	0.384
K82.0 Obstruction of gallbladder	0.616	0.384
S92.9 Fracture of foot, unspecified	0.615	0.385
S92.7 Multiple fractures of foot	0.615	0.385
S92.5 Fracture of other toe	0.615	0.385
Y52 Agents primarily affecting the cardiovascular system	0.614	0.386
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.614	0.386
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.614	0.386
L81 Other disorders of pigmentation	0.613	0.387
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.613	0.387
J35.2 Hypertrophy of adenoids	0.613	0.387
I82.3 Embolism and thrombosis of renal vein	0.613	0.387
I82.1 Thrombophlebitis migrans	0.613	0.387
I82.0 Budd-Chiari syndrome	0.613	0.387
D68.2 Hereditary deficiency of other clotting factors	0.612	0.388
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.612	0.388
Q65 Congenital deformities of hip	0.612	0.388
T82.1 Mechanical complication of cardiac electronic device	0.611	0.389
N15 Other renal tubulo-interstitial diseases	0.609	0.390
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.608	0.391
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.608	0.392
I47.2 Ventricular tachycardia	0.608	0.392
L83 Acanthosis nigricans	0.607	0.393
T93 Sequelae of injuries of lower limb	0.607	0.393
Q51 Congenital malformations of uterus and cervix	0.606	0.394
T91 Sequelae of injuries of neck and trunk	0.606	0.394
E22.9 Hyperfunction of pituitary gland, unspecified	0.606	0.394
E22.8 Other hyperfunction of pituitary gland	0.606	0.394
I71 Aortic aneurysm and dissection	0.606	0.394
E22.0 Acromegaly and pituitary gigantism	0.604	0.396
I10-I15 Hypertensive diseases	0.604	0.396
L53.8 Other specified erythematous conditions	0.604	0.396
L53.3 Other chronic figurate erythema	0.604	0.396
L53.2 Erythema marginatum	0.604	0.396
L53.1 Erythema annulare centrifugum	0.604	0.396
L53.0 Toxic erythema	0.604	0.396
L60-L75 Disorders of skin appendages	0.603	0.397
J37.0 Chronic laryngitis	0.603	0.397
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.603	0.397
I44.0 Atrioventricular block, first degree	0.603	0.397
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.602	0.398
K35.3 Acute appendicitis with localized peritonitis	0.601	0.398
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.601	0.398
N27 Small kidney of unknown cause	0.601	0.398
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.601	0.399
N99-N99 Other disorders of the genitourinary system	0.601	0.399
L27 Dermatitis due to substances taken internally	0.601	0.399
I97.9 Postprocedural disorder of circulatory system, unspecified	0.600	0.400
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.600	0.400
I97.0 Postcardiotomy syndrome	0.600	0.400
E10-E14 Diabetes mellitus	0.600	0.400
I95.0 Idiopathic hypotension	0.599	0.401
T82.3 Mechanical complication of other vascular grafts	0.599	0.401
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.598	0.402
E23.7 Disorder of pituitary gland, unspecified	0.598	0.402
E23.6 Other disorders of pituitary gland	0.598	0.402
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.598	0.402
E23.1 Drug-induced hypopituitarism	0.598	0.402
S36.0 Injury of spleen	0.596	0.404
I51.6 Cardiovascular disease, unspecified	0.596	0.404
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.596	0.404
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.596	0.404
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.595	0.404
S50-S59 Injuries to the elbow and forearm	0.595	0.405
T94 Sequelae of injuries involving multiple and unspecified body regions	0.595	0.405
E50-E64 Other nutritional deficiencies	0.595	0.405
J15.2 Pneumonia due to staphylococcus	0.594	0.406
T87 Complications peculiar to reattachment and amputation	0.594	0.406
J30.1 Allergic rhinitis due to pollen	0.593	0.407
N08 Glomerular disorders in diseases classified elsewhere	0.593	0.407
J18.8 Other pneumonia, organism unspecified	0.593	0.407
J18.2 Hypostatic pneumonia, unspecified	0.593	0.407
S60.8 Other superficial injuries of wrist and hand	0.589	0.411
T14 Injury of unspecified body region	0.589	0.411
K81 Cholecystitis	0.588	0.412
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.588	0.412
S92.0 Fracture of calcaneus	0.588	0.412
I82.9 Embolism and thrombosis of unspecified vein	0.587	0.413
J21.9 Acute bronchiolitis, unspecified	0.587	0.413
J81 Pulmonary oedema	0.587	0.413
J14 Pneumonia due to Haemophilus influenzae	0.586	0.414
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.586	0.414
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.586	0.414
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.586	0.414
Q75 Other congenital malformations of skull and face bones	0.586	0.414
Q74 Other congenital malformations of limb(s)	0.586	0.414
Q73 Reduction defects of unspecified limb	0.586	0.414

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations