TreeWAS – Variant ID: rs75112989

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
M79.86 Other specified soft tissue disorders (Lower leg)	1.000	0.000
D68.5 Primary Thrombophilia	1.000	0.000
D68.2 Hereditary deficiency of other clotting factors	1.000	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	1.000	0.000
D68 Other coagulation defects	1.000	0.000
I80 Phlebitis and thrombophlebitis	1.000	0.000
M79 Other soft tissue disorders, not elsewhere classified	1.000	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
M79.8 Other specified soft tissue disorders	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	1.000	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	1.000	0.000
I26 Pulmonary embolism	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000
M70-M79 Other soft tissue disorders	1.000	0.000
Z91 Personal history of risk-factors, not elsewhere classified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
M79.66 Pain in limb (Lower leg)	1.000	0.000
M79.6 Pain in limb	0.999	0.001
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.999	0.001
Z92 Personal history of medical treatment	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.998	0.002
Z86 Personal history of certain other diseases	0.998	0.002
Chapter V Mental and behavioural disorders	0.997	0.003
I82 Other venous embolism and thrombosis	0.996	0.004
D68.8 Other specified coagulation defects	0.995	0.005
S20-S29 Injuries to the thorax	0.994	0.006
Chapter I Certain infectious and parasitic diseases	0.992	0.008
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.990	0.010
M86-M90 Other osteopathies	0.989	0.011
I82.8 Embolism and thrombosis of other specified veins	0.986	0.014
M20-M25 Other joint disorders	0.982	0.018
I83 Varicose veins of lower extremities	0.982	0.018
M23 Internal derangement of knee	0.970	0.030
Chapter XV Pregnancy, childbirth and the puerperium	0.969	0.031
D80-D89 Certain disorders involving the immune mechanism	0.968	0.032
M23.2 Derangement of meniscus due to old tear or injury	0.968	0.032
F00-F09 Organic, including symptomatic, mental disorders	0.967	0.033
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.959	0.041
Chapter IV Endocrine, nutritional and metabolic diseases	0.957	0.043
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.956	0.044
Z70-Z76 Persons encountering health services in other circumstances	0.955	0.045
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.952	0.048
S20 Superficial injury of thorax	0.950	0.050
D17 Benign lipomatous neoplasm	0.945	0.055
S70-S79 Injuries to the hip and thigh	0.945	0.055
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.945	0.055
M05-M14 Inflammatory polyarthropathies	0.941	0.059
T85 Complications of other internal prosthetic devices, implants and grafts	0.940	0.060
Z89 Acquired absence of limb	0.937	0.063
A00-A09 Intestinal infectious diseases	0.936	0.064
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.935	0.065
D86 Sarcoidosis	0.934	0.066
M89 Other disorders of bone	0.931	0.069
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.931	0.069
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.930	0.070
Z91.5 Personal history of self-harm	0.928	0.072
F60-F69 Disorders of adult personality and behaviour	0.926	0.074
S20.8 Superficial injuries of other and unspecified parts of thorax	0.925	0.075
F40-F48 Neurotic, stress-related and somatoform disorders	0.922	0.078
B95-B98 Bacterial, viral and other infectious agents	0.921	0.079
F03 Unspecified dementia	0.920	0.080
M65-M68 Disorders of synovium and tendon	0.918	0.082
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.918	0.082
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.915	0.085
M25 Other joint disorders, not elsewhere classified	0.914	0.086
E16 Other disorders of pancreatic internal secretion	0.912	0.088
M13 Other arthritis	0.910	0.090
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.904	0.096
A09.9 Gastroenteritis and colitis of unspecified origin	0.901	0.099
Z86.5 Personal history of other mental and behavioural disorders	0.901	0.099
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.898	0.102
I82.9 Embolism and thrombosis of unspecified vein	0.897	0.103
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.897	0.103
S72 Fracture of femur	0.894	0.106
M79.1 Myalgia	0.893	0.107
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.893	0.107
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.891	0.109
M90 Osteopathies in diseases classified elsewhere	0.891	0.109
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.890	0.110
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.890	0.110
S22 Fracture of rib(s), sternum and thoracic spine	0.889	0.111
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.888	0.112
M67 Other disorders of synovium and tendon	0.886	0.114
T20-T25 Burns and corrosions of external body surface, specified by site	0.885	0.115
E16.2 Hypoglycaemia, unspecified	0.884	0.116
Z40-Z54 Persons encountering health services for specific procedures and health care	0.881	0.119
M79.89 Other specified soft tissue disorders (Site unspecified)	0.880	0.120
Z89.4 Acquired absence of foot and ankle	0.875	0.125
M25.8 Other specified joint disorders	0.874	0.126
M89.8 Other specified disorders of bone	0.873	0.126
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.872	0.128
M79.65 Pain in limb (Pelvic region and thigh)	0.870	0.130
D17.6 Benign lipomatous neoplasm of spermatic cord	0.869	0.131
Z73 Problems related to life-management difficulty	0.866	0.134
M13.9 Arthritis, unspecified	0.865	0.135
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.862	0.138
M50-M54 Other dorsopathies	0.861	0.139
I86 Varicose veins of other sites	0.861	0.139
F60 Specific personality disorders	0.858	0.142
F40 Phobic anxiety disorders	0.858	0.142
S27 Injury of other and unspecified intrathoracic organs	0.856	0.144
Chapter XX External causes of morbidity and mortality	0.856	0.144
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.851	0.149
D86.0 Sarcoidosis of lung	0.850	0.150
O94-O99 Other obstetric conditions, not elsewhere classified	0.849	0.151
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.847	0.153
I27 Other pulmonary heart diseases	0.845	0.155
E00-E07 Disorders of thyroid gland	0.844	0.156
B20-B24 Human immunodeficiency virus [HIV] disease	0.844	0.156
M24 Other specific joint derangements	0.840	0.160
T93 Sequelae of injuries of lower limb	0.837	0.163
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.835	0.165
D86.9 Sarcoidosis, unspecified	0.835	0.165
F43 Reaction to severe stress, and adjustment disorders	0.834	0.166
M50 Cervical disk disorders	0.832	0.168
Z74 Problems related to care-provider dependency	0.831	0.169
M86 Osteomyelitis	0.831	0.169
M79.84 Other specified soft tissue disorders (Hand)	0.829	0.171
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.828	0.172
Z99.2 Dependence on renal dialysis	0.828	0.172
E04 Other non-toxic goitre	0.827	0.173
B02 Zoster [herpes zoster]	0.827	0.173
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.826	0.173
Chapter VII Diseases of the eye and adnexa	0.826	0.174
M25.86 Other specified joint disorders (Lower leg)	0.826	0.174
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.824	0.176
I83.1 Varicose veins of lower extremities with inflammation	0.823	0.177
M91-M94 Chondropathies	0.822	0.178
Z48 Other surgical follow-up care	0.822	0.178
M90.7 Fracture of bone in neoplastic disease	0.821	0.179
M25.3 Other instability of joint	0.819	0.181
M76 Enthesopathies of lower limb, excluding foot	0.817	0.182
Z99.3 Dependence on wheelchair	0.816	0.184
Z84 Family history of other conditions	0.814	0.186
M79.69 Pain in limb (Site unspecified)	0.814	0.186
S72.1 Pertrochanteric fracture	0.814	0.186
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.814	0.186
O85-O92 Complications predominantly related to the puerperium	0.813	0.187
Chapter XXII Codes for special purposes	0.812	0.188
I83.0 Varicose veins of lower extremities with ulcer	0.811	0.189
S72.0 Fracture of neck of femur	0.804	0.196
D66 Hereditary factor VIII deficiency	0.804	0.196
T15-T19 Effects of foreign body entering through natural orifice	0.804	0.196
F40.2 Specific (isolated) phobias	0.803	0.197
S29 Other and unspecified injuries of thorax	0.801	0.199
Z73.9 Problem related to life-management difficulty, unspecified	0.800	0.200
M22 Disorders of patella	0.800	0.200
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.800	0.200
M89.87 Other specified disorders of bone (Ankle and foot)	0.799	0.201
I80.8 Phlebitis and thrombophlebitis of other sites	0.799	0.201
Z94 Transplanted organ and tissue status	0.799	0.201
D68.9 Coagulation defect, unspecified	0.796	0.204
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.795	0.205
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.794	0.206
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.793	0.207
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.792	0.208
F99-F99 Unspecified mental disorder	0.792	0.208
M67.1 Other contracture of tendon (sheath)	0.791	0.209
M13.93 Arthritis, unspecified (Forearm)	0.790	0.210
T87 Complications peculiar to reattachment and amputation	0.790	0.210
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.789	0.211
Z76 Persons encountering health services in other circumstances	0.788	0.212
Z48.0 Attention to surgical dressings and sutures	0.788	0.212
M71 Other bursopathies	0.785	0.215
T66-T78 Other and unspecified effects of external causes	0.784	0.216
E16.1 Other hypoglycaemia	0.784	0.216
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.783	0.217
H40-H42 Glaucoma	0.783	0.217
E04.1 Non-toxic single thyroid nodule	0.781	0.219
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.780	0.220
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.779	0.221
M88 Paget's disease of bone [osteitis deformans]	0.776	0.223
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.776	0.224
Z50 Care involving use of rehabilitation procedures	0.774	0.226
B07 Viral warts	0.773	0.227
Z81 Family history of mental and behavioural disorders	0.772	0.228
T85.2 Mechanical complication of intraocular lens	0.772	0.228
S21 Open wound of thorax	0.771	0.229
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.767	0.233
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.767	0.233
O60-O75 Complications of labour and delivery	0.767	0.233
M67.2 Synovial hypertrophy, not elsewhere classified	0.765	0.234
F25 Schizoaffective disorders	0.765	0.235
S79 Other and unspecified injuries of hip and thigh	0.765	0.235
D17.9 Benign lipomatous neoplasm, unspecified	0.763	0.237
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.763	0.237
M50.3 Other cervical disk degeneration	0.763	0.237
E04.2 Non-toxic multinodular goitre	0.758	0.242
F60.9 Personality disorder, unspecified	0.758	0.242
F01 Vascular dementia	0.758	0.242
S72.10 Pertrochanteric fracture (closed)	0.757	0.243
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.756	0.243
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.756	0.244
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.756	0.244
I27.2 Other secondary pulmonary hypertension	0.754	0.246
M79.19 Myalgia (Site unspecified)	0.753	0.247
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.753	0.247
M79.9 Soft tissue disorder, unspecified	0.753	0.247
Z42 Follow-up care involving plastic surgery	0.753	0.247
H40 Glaucoma	0.752	0.248
A15-A19 Tuberculosis	0.749	0.251
D70-D77 Other diseases of blood and blood-forming organs	0.748	0.252
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.748	0.252
M25.84 Other specified joint disorders (Hand)	0.746	0.254
T31 Burns classified according to extent of body surface involved	0.745	0.255
F43.2 Adjustment disorders	0.743	0.257
B90-B94 Sequelae of infectious and parasitic diseases	0.742	0.258
E50-E64 Other nutritional deficiencies	0.742	0.258
F60.3 Emotionally unstable personality disorder	0.742	0.258
I86.4 Gastric varices	0.741	0.259
M77 Other enthesopathies	0.741	0.259
S72.00 Fracture of neck of femur (closed)	0.740	0.260
A80-A89 Viral infections of the central nervous system	0.739	0.261
B24 Unspecified human immunodeficiency virus [HIV] disease	0.738	0.262
S22.1 Multiple fractures of thoracic spine	0.738	0.262
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.737	0.263
T86 Failure and rejection of transplanted organs and tissues	0.736	0.264
Z74.0 Reduced mobility	0.736	0.264
M33 Dermatopolymyositis	0.735	0.265
M89.86 Other specified disorders of bone (Lower leg)	0.735	0.265
M89.9 Disorder of bone, unspecified	0.735	0.265
M50.2 Other cervical disk displacement	0.733	0.267
Z75 Problems related to medical facilities and other health care	0.733	0.267
S10-S19 Injuries to the neck	0.733	0.267
Z91.6 Personal history of other physical trauma	0.732	0.268
M90.78 Fracture of bone in neoplastic disease (Other)	0.732	0.268
M23.8 Other internal derangements of knee	0.732	0.268
B02.9 Zoster without complication	0.732	0.268
T80 Complications following infusion, transfusion and therapeutic injection	0.731	0.268
O47 False labour	0.731	0.269
D86.8 Sarcoidosis of other and combined sites	0.730	0.270
H50 Other strabismus	0.729	0.271
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.729	0.271
M79.64 Pain in limb (Hand)	0.728	0.272
Z44 Fitting and adjustment of external prosthetic device	0.727	0.273
M25.33 Other instability of joint (Forearm)	0.727	0.273
I88 Nonspecific lymphadenitis	0.725	0.275
F69 Unspecified disorder of adult personality and behaviour	0.725	0.275
A50-A64 Infections with a predominantly sexual mode of transmission	0.725	0.275
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.724	0.276
X10-X19 Contact with heat and hot substances	0.724	0.276
F05 Delirium, not induced by alcohol and other psychoactive substances	0.724	0.276
I82.2 Embolism and thrombosis of vena cava	0.724	0.276
M05 Seropositive rheumatoid arthritis	0.723	0.277
I95-I99 Other and unspecified disorders of the circulatory system	0.723	0.277
Z92.8 Personal history of other medical treatment	0.722	0.278
M34 Systemic sclerosis	0.722	0.278
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.721	0.278
T93.2 Sequelae of other fractures of lower limb	0.721	0.279
S50-S59 Injuries to the elbow and forearm	0.720	0.280
M13.0 Polyarthritis, unspecified	0.719	0.281
M67.8 Other specified disorders of synovium and tendon	0.719	0.281
S90-S99 Injuries to the ankle and foot	0.718	0.281
M86.9 Osteomyelitis, unspecified	0.718	0.282
Z71.4 Alcohol abuse counselling and surveillance	0.718	0.282
M87 Osteonecrosis	0.717	0.283
D68.6 Other Thrombophilia	0.717	0.283
D68.4 Acquired coagulation factor deficiency	0.717	0.283
D68.1 Hereditary factor XI deficiency	0.717	0.283
M79.4 Hypertrophy of (infrapatellar) fat pad	0.717	0.283
M79.3 Panniculitis, unspecified	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M79.88 Other specified soft tissue disorders (Other)	0.717	0.283
M79.83 Other specified soft tissue disorders (Forearm)	0.717	0.283
M79.82 Other specified soft tissue disorders (Upper arm)	0.717	0.283
M79.81 Other specified soft tissue disorders (Shoulder region)	0.717	0.283
I28 Other diseases of pulmonary vessels	0.717	0.283
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.717	0.283
D67 Hereditary factor IX deficiency	0.717	0.283
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.717	0.283
M73 Soft tissue disorders in diseases classified elsewhere	0.717	0.283
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.717	0.283
Z91.7 Personal history of female genital mutilation	0.717	0.283
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.717	0.283
Z91.3 Personal history of unhealthy sleep-wake schedule	0.717	0.283
Z91.2 Personal history of poor personal hygiene	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
M79.68 Pain in limb (Other)	0.717	0.283
M79.61 Pain in limb (Shoulder region)	0.717	0.283
M11 Other crystal arthropathies	0.717	0.283
M24.2 Disorder of ligament	0.717	0.283
M79.10 Myalgia (Multiple sites)	0.716	0.284
Z92.9 Personal history of medical treatment, unspecified	0.716	0.284
Z92.5 Personal history of rehabilitation measures	0.716	0.284
Z92.0 Personal history of contraception	0.716	0.284
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.715	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.715	0.285
I82.3 Embolism and thrombosis of renal vein	0.714	0.286
I82.1 Thrombophlebitis migrans	0.714	0.286
I82.0 Budd-Chiari syndrome	0.714	0.286
S22.2 Fracture of sternum	0.713	0.287
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.712	0.288
S26 Injury of heart	0.712	0.288
S25 Injury of blood vessels of thorax	0.712	0.288
S24 Injury of nerves and spinal cord at thorax level	0.712	0.288
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.712	0.288
Z99.1 Dependence on respirator	0.712	0.288
T23 Burn and corrosion of wrist and hand	0.711	0.289
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.289
B50-B64 Protozoal diseases	0.711	0.289
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.289
A75-A79 Rickettsioses	0.711	0.289
A70-A74 Other diseases caused by chlamydiae	0.711	0.289
A65-A69 Other spirochaetal diseases	0.711	0.289
A20-A28 Certain zoonotic bacterial diseases	0.711	0.289
Z49 Care involving dialysis	0.711	0.289
Z89.5 Acquired absence of leg at or below knee	0.710	0.290
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.710	0.290
E10-E14 Diabetes mellitus	0.710	0.290
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.709	0.291
B25-B34 Other viral diseases	0.709	0.291
O40 Polyhydramnios	0.707	0.293
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.706	0.294
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.705	0.295
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.705	0.295
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.705	0.295
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.704	0.296
M32 Systemic lupus erythematosus	0.704	0.296
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.704	0.296
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.704	0.296
M50.1 Cervical disk disorder with radiculopathy	0.703	0.297
M23.0 Cystic meniscus	0.703	0.297
M24.4 Recurrent dislocation and subluxation of joint	0.702	0.298
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.702	0.298
H40.9 Glaucoma, unspecified	0.701	0.299
M13.1 Monoarthritis, not elsewhere classified	0.700	0.300
O43 Placental disorders	0.700	0.300
F48 Other neurotic disorders	0.700	0.300
F43.0 Acute stress reaction	0.700	0.300
E65-E68 Obesity and other hyperalimentation	0.699	0.301
M13.8 Other specified arthritis	0.699	0.301
T90 Sequelae of injuries of head	0.699	0.301
S27.0 Traumatic pneumothorax	0.698	0.302
M67.4 Ganglion	0.698	0.302
O32 Maternal care for known or suspected malpresentation of foetus	0.698	0.302
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.698	0.302
M79.2 Neuralgia and neuritis, unspecified	0.697	0.303
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.697	0.303
M79.18 Myalgia (Other)	0.696	0.304
T93.8 Sequelae of other specified injuries of lower limb	0.696	0.304
M23.6 Other spontaneous disruption of ligament(s) of knee	0.695	0.305
M23.1 Discoid meniscus (congenital)	0.695	0.305
M00-M03 Infectious arthropathies	0.695	0.305
M30 Polyarteritis nodosa and related conditions	0.694	0.305
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.694	0.305
T94 Sequelae of injuries involving multiple and unspecified body regions	0.694	0.306
D84 Other immunodeficiencies	0.694	0.306
D83 Common variable immunodeficiency	0.694	0.306
D82 Immunodeficiency associated with other major defects	0.694	0.306
D81 Combined immunodeficiencies	0.694	0.306
M21 Other acquired deformities of limbs	0.694	0.306
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.694	0.306
Z88.5 Personal history of allergy to narcotic agent	0.694	0.306
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.693	0.307
F02 Dementia in other diseases classified elsewhere	0.693	0.307
F09 Unspecified organic or symptomatic mental disorder	0.693	0.307
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.693	0.307
O68 Labour and delivery complicated by foetal stress [distress]	0.693	0.307
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.693	0.307
F00 Dementia in Alzheimer's disease	0.693	0.307
M40-M43 Deforming dorsopathies	0.693	0.307
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.692	0.307
B02.3 Zoster ocular disease	0.692	0.308
H46-H48 Disorders of optic nerve and visual pathways	0.692	0.308
M23.9 Internal derangement of knee, unspecified	0.691	0.309
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.691	0.309
M13.98 Arthritis, unspecified (Other)	0.690	0.310
M60-M63 Disorders of muscles	0.689	0.311
M79.5 Residual foreign body in soft tissue	0.688	0.312
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.688	0.312
Z94.0 Kidney transplant status	0.688	0.312
V01-V09 Pedestrian injured in transport accident	0.688	0.312
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.687	0.313
W20-W49 Exposure to inanimate mechanical forces	0.687	0.313
S22.0 Fracture of thoracic vertebra	0.687	0.313
M25.4 Effusion of joint	0.687	0.313
I85 Oesophageal varices	0.687	0.313
F80-F89 Disorders of psychological development	0.686	0.313
M14 Arthropathies in other diseases classified elsewhere	0.686	0.314
Z70 Counselling related to sexual attitude, behaviour and orientation	0.685	0.315
M25.7 Osteophyte	0.685	0.315
Z45 Adjustment and management of implanted device	0.685	0.315
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.685	0.315
O34 Maternal care for known or suspected abnormality of pelvic organs	0.683	0.317
M89.5 Osteolysis	0.682	0.317
O90 Complications of the puerperium, not elsewhere classified	0.682	0.318
D80 Immunodeficiency with predominantly antibody defects	0.682	0.318
S20.7 Multiple superficial injuries of thorax	0.681	0.319
S20.4 Other superficial injuries of back wall of thorax	0.681	0.319
S20.3 Other superficial injuries of front wall of thorax	0.681	0.319
S20.1 Other and unspecified superficial injuries of breast	0.681	0.319
S20.0 Contusion of breast	0.681	0.319
T88 Other complications of surgical and medical care, not elsewhere classified	0.681	0.319
Z88.1 Personal history of allergy to other antibiotic agents	0.680	0.320
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.678	0.321
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.678	0.322
S78 Traumatic amputation of hip and thigh	0.677	0.322
S77 Crushing injury of hip and thigh	0.677	0.322
S76 Injury of muscle and tendon at hip and thigh level	0.677	0.322
S75 Injury of blood vessels at hip and thigh level	0.677	0.322
S74 Injury of nerves at hip and thigh level	0.677	0.322
S71 Open wound of hip and thigh	0.677	0.322
Z89.6 Acquired absence of leg above knee	0.676	0.324
M10 Gout	0.676	0.324
M13.96 Arthritis, unspecified (Lower leg)	0.676	0.324
E11 Non-insulin-dependent diabetes mellitus	0.676	0.324
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.675	0.325
Z50.8 Care involving use of rehabilitation procedures	0.675	0.325
M12 Other specific arthropathies	0.675	0.325
M09 Juvenile arthritis in diseases classified elsewhere	0.675	0.325
M08 Juvenile arthritis	0.675	0.325
F45 Somatoform disorders	0.674	0.326
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.674	0.326
K70-K77 Diseases of liver	0.673	0.327
K76 Other diseases of liver	0.673	0.327
F23 Acute and transient psychotic disorders	0.672	0.328
Z89.9 Acquired absence of limb, unspecified	0.672	0.328
Z89.8 Acquired absence of upper and lower limbs [any level]	0.672	0.328
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.672	0.328
Z89.3 Acquired absence of both upper limbs [any level]	0.672	0.328
Z89.2 Acquired absence of upper limb above wrist	0.672	0.328
Z89.1 Acquired absence of hand and wrist	0.672	0.328
K76.0 Fatty (change of) liver, not elsewhere classified	0.672	0.328
D72 Other disorders of white blood cells	0.671	0.329
A07 Other protozoal intestinal diseases	0.671	0.329
A06 Amoebiasis	0.671	0.329
A05 Other bacterial foodborne intoxications	0.671	0.329
A03 Shigellosis	0.671	0.329
A01 Typhoid and paratyphoid fevers	0.671	0.329
A00 Cholera	0.671	0.329
Z42.0 Follow-up care involving plastic surgery of head and neck	0.671	0.329
O47.1 False labour at or after 37 completed weeks of gestation	0.671	0.329
O15 Eclampsia	0.671	0.329
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.671	0.329
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.671	0.329
D86.3 Sarcoidosis of skin	0.670	0.330
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.670	0.330
D86.1 Sarcoidosis of lymph nodes	0.670	0.330
F25.9 Schizoaffective disorder, unspecified	0.669	0.331
T31.0 Burns involving less than 10% of body surface	0.669	0.331
S27.3 Other injuries of lung	0.668	0.332
D89.2 Hypergammaglobulinaemia, unspecified	0.668	0.332
M89.6 Osteopathy after poliomyelitis	0.668	0.332
M89.4 Other hypertrophic osteo-arthropathy	0.668	0.332
M89.3 Hypertrophy of bone	0.668	0.332
M89.2 Other disorders of bone development and growth	0.668	0.332
M89.1 Epiphyseal arrest	0.668	0.332
M89.0 Algoneurodystrophy	0.668	0.332
E15 Nondiabetic hypoglycaemic coma	0.667	0.333
D55-D59 Haemolytic anaemias	0.667	0.333
Z99.9 Dependence on unspecified enabling machine and device	0.666	0.333
Z99.4 Dependence on artificial heart	0.666	0.333
Z99.0 Dependence on aspirator	0.666	0.333
M25.87 Other specified joint disorders (Ankle and foot)	0.666	0.334
H50.1 Divergent concomitant strabismus	0.666	0.334
T20 Burn and corrosion of head and neck	0.666	0.334
S72.2 Subtrochanteric fracture	0.665	0.335
T93.9 Sequelae of unspecified injury of lower limb	0.665	0.335
B65-B83 Helminthiases	0.664	0.335
E20-E35 Disorders of other endocrine glands	0.665	0.335
M76.6 Achilles tendinitis	0.664	0.336
F68 Other disorders of adult personality and behaviour	0.664	0.336
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.664	0.336
F65 Disorders of sexual preference	0.664	0.336
F64 Gender identity disorders	0.664	0.336
F63 Habit and impulse disorders	0.664	0.336
F62 Enduring personality changes, not attributable to brain damage and disease	0.664	0.336
F61 Mixed and other personality disorders	0.664	0.336
I98 Other disorders of circulatory system in diseases classified elsewhere	0.663	0.337
O14.0 Moderate preeclampsia	0.663	0.337
S29.9 Unspecified injury of thorax	0.662	0.338
S27.1 Traumatic haemothorax	0.662	0.338
I86.8 Varicose veins of other specified sites	0.662	0.338
S22.4 Multiple fractures of ribs	0.662	0.338
F44 Dissociative [conversion] disorders	0.661	0.339
E40-E46 Malnutrition	0.660	0.340
Z52 Donors of organs and tissues	0.660	0.340
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.658	0.342
B06 Rubella [German measles]	0.658	0.342
B05 Measles	0.658	0.342
B01 Varicella [chickenpox]	0.658	0.342
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.658	0.342
B04 Monkeypox	0.658	0.342
B03 Smallpox	0.658	0.342
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.658	0.342
O16 Unspecified maternal hypertension	0.658	0.342

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations