TreeWAS – Variant ID: rs7569716

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.304	0.696	0.000
M80-M85 Disorders of bone density and structure	0.299	0.701	0.000
M45-M49 Spondylopathies	0.298	0.702	0.000
M48 Other spondylopathies	0.292	0.708	0.000
M80 Osteoporosis with pathological fracture	0.289	0.711	0.000
M48.0 Spinal stenosis	0.287	0.713	0.000
M86-M90 Other osteopathies	0.283	0.717	0.000
M20-M25 Other joint disorders	0.283	0.717	0.000
M65-M68 Disorders of synovium and tendon	0.279	0.721	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.272	0.728	0.000
M22 Disorders of patella	0.272	0.728	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.268	0.732	0.000
M31 Other necrotising vasculopathies	0.267	0.733	0.000
M89 Other disorders of bone	0.263	0.737	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.258	0.742	0.000
M85 Other disorders of bone density and structure	0.258	0.742	0.000
M47 Spondylosis	0.257	0.743	0.000
M65 Synovitis and tenosynovitis	0.249	0.751	0.000
M22.4 Chondromalacia patellae	0.248	0.752	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.248	0.752	0.000
M81 Osteoporosis without pathological fracture	0.246	0.754	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.246	0.754	0.000
M00-M03 Infectious arthropathies	0.245	0.754	0.000
M24 Other specific joint derangements	0.243	0.757	0.000
M21 Other acquired deformities of limbs	0.243	0.757	0.000
M50-M54 Other dorsopathies	0.243	0.757	0.000
M46 Other inflammatory spondylopathies	0.242	0.758	0.000
M48.02 Spinal stenosis (Cervical region)	0.241	0.759	0.000
M86 Osteomyelitis	0.237	0.763	0.000
M85.8 Other specified disorders of bone density and structure	0.237	0.763	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.236	0.764	0.000
M81.4 Drug-induced osteoporosis	0.236	0.764	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.236	0.764	0.000
M91-M94 Chondropathies	0.235	0.765	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.234	0.766	0.000
M48.04 Spinal stenosis (Thoracic region)	0.233	0.767	0.000
M21.1 Varus deformity, not elsewhere classified	0.231	0.769	0.000
M89.5 Osteolysis	0.231	0.769	0.000
M31.6 Other giant cell arteritis	0.231	0.769	0.000
M47.9 Spondylosis, unspecified	0.230	0.770	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.230	0.770	0.000
M22.0 Recurrent dislocation of patella	0.229	0.771	0.000
M22.2 Patellofemoral disorders	0.229	0.771	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.227	0.773	0.000
M31.9 Necrotising vasculopathy, unspecified	0.225	0.775	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.224	0.776	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.223	0.776	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.223	0.777	0.000
M47.2 Other spondylosis with radiculopathy	0.223	0.777	0.000
M90 Osteopathies in diseases classified elsewhere	0.222	0.778	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.222	0.778	0.000
M89.9 Disorder of bone, unspecified	0.220	0.780	0.000
M66 Spontaneous rupture of synovium and tendon	0.218	0.781	0.000
M67 Other disorders of synovium and tendon	0.218	0.782	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.216	0.784	0.000
M83 Adult osteomalacia	0.215	0.785	0.000
M48.06 Spinal stenosis (Lumbar region)	0.214	0.786	0.000
M24.2 Disorder of ligament	0.214	0.786	0.000
M05-M14 Inflammatory polyarthropathies	0.213	0.787	0.000
M80.8 Other osteoporosis with pathological fracture	0.212	0.788	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.212	0.788	0.000
M60-M63 Disorders of muscles	0.212	0.788	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.211	0.789	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.210	0.790	0.000
M48.9 Spondylopathy, unspecified	0.210	0.790	0.000
M48.8 Other specified spondylopathies	0.210	0.790	0.000
M48.4 Fatigue fracture of vertebra	0.210	0.790	0.000
M48.3 Traumatic spondylopathy	0.210	0.790	0.000
M48.2 Kissing spine	0.210	0.790	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.210	0.790	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.210	0.790	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.209	0.791	0.000
M50 Cervical disk disorders	0.209	0.791	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.208	0.792	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.207	0.792	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.207	0.792	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.207	0.792	0.000
M54 Dorsalgia	0.207	0.793	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.206	0.794	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.206	0.794	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.206	0.794	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.206	0.794	0.000
M00 Pyogenic arthritis	0.203	0.797	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.203	0.797	0.000
M32 Systemic lupus erythematosus	0.203	0.797	0.000
M89.8 Other specified disorders of bone	0.202	0.798	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.202	0.798	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.200	0.800	0.000
M82 Osteoporosis in diseases classified elsewhere	0.200	0.800	0.000
M89.0 Algoneurodystrophy	0.200	0.800	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.199	0.801	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.199	0.801	0.000
M24.6 Ankylosis of joint	0.199	0.801	0.000
M49 Spondylopathies in diseases classified elsewhere	0.198	0.802	0.000
M33 Dermatopolymyositis	0.198	0.802	0.000
M22.3 Other derangements of patella	0.198	0.802	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.197	0.803	0.000
M84 Disorders of continuity of bone	0.196	0.804	0.000
M86.6 Other chronic osteomyelitis	0.196	0.804	0.000
M24.1 Other articular cartilage disorders	0.195	0.804	0.000
M40-M43 Deforming dorsopathies	0.195	0.805	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.195	0.805	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.195	0.805	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.195	0.805	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.195	0.805	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.195	0.805	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.195	0.805	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.195	0.805	0.000
M22.1 Recurrent subluxation of patella	0.195	0.805	0.000
M22.9 Disorder of patella, unspecified	0.195	0.805	0.000
M89.56 Osteolysis (Lower leg)	0.193	0.807	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.192	0.808	0.000
M31.8 Other specified necrotising vasculopathies	0.191	0.809	0.000
M31.7 Microscopic polyangiitis	0.191	0.809	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.191	0.809	0.000
M31.2 Lethal midline granuloma	0.191	0.809	0.000
M31.1 Thrombotic microangiopathy	0.191	0.809	0.000
M31.0 Hypersensitivity angiitis	0.191	0.809	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.190	0.810	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.190	0.810	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.190	0.810	0.000
M87 Osteonecrosis	0.189	0.811	0.000
M89.6 Osteopathy after poliomyelitis	0.189	0.811	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.189	0.811	0.000
M89.2 Other disorders of bone development and growth	0.189	0.811	0.000
M89.1 Epiphyseal arrest	0.189	0.811	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.186	0.814	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.186	0.814	0.000
M50.2 Other cervical disk displacement	0.186	0.814	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.186	0.814	0.000
M54.9 Dorsalgia, unspecified	0.185	0.815	0.000
M85.9 Disorder of bone density and structure, unspecified	0.185	0.815	0.000
M85.5 Aneurysmal bone cyst	0.185	0.815	0.000
M85.4 Solitary bone cyst	0.185	0.815	0.000
M85.3 Osteitis condensans	0.185	0.815	0.000
M85.2 Hyperostosis of skull	0.185	0.815	0.000
M85.1 Skeletal fluorosis	0.185	0.815	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.184	0.816	0.000
M89.98 Disorder of bone, unspecified (Other)	0.183	0.816	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.183	0.817	0.000
M21.4 Flat foot [pes planus] (acquired)	0.183	0.817	0.000
M30 Polyarteritis nodosa and related conditions	0.183	0.817	0.000
M86.9 Osteomyelitis, unspecified	0.183	0.817	0.000
M65.1 Other infective (teno)synovitis	0.183	0.817	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.181	0.819	0.000
M07 Psoriatic and enteropathic arthropathies	0.180	0.820	0.000
M85.6 Other cyst of bone	0.180	0.820	0.000
M23 Internal derangement of knee	0.180	0.820	0.000
M24.7 Protrusio acetabuli	0.180	0.820	0.000
M22.8 Other disorders of patella	0.180	0.820	0.000
M89.3 Hypertrophy of bone	0.179	0.821	0.000
M65.2 Calcific tendinitis	0.179	0.821	0.000
M65.0 Abscess of tendon sheath	0.179	0.821	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.178	0.822	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.178	0.822	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.178	0.822	0.000
M54.6 Pain in thoracic spine	0.178	0.822	0.000
M47.1 Other spondylosis with myelopathy	0.178	0.822	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.177	0.823	0.000
M50.3 Other cervical disk degeneration	0.177	0.823	0.000
M81.8 Other osteoporosis	0.176	0.823	0.000
M81.6 Localised osteoporosis [Lequesne]	0.176	0.823	0.000
M81.5 Idiopathic osteoporosis	0.176	0.823	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.176	0.823	0.000
M81.1 Postoophorectomy osteoporosis	0.176	0.823	0.000
M81.0 Postmenopausal osteoporosis	0.176	0.823	0.000
M99 Biomechanical lesions, not elsewhere classified	0.176	0.824	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.176	0.824	0.000
M02 Reactive arthropathies	0.176	0.824	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.176	0.824	0.000
M66.2 Spontaneous rupture of extensor tendons	0.176	0.824	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.176	0.824	0.000
M24.9 Joint derangement, unspecified	0.175	0.825	0.000
M21.9 Acquired deformity of limb, unspecified	0.174	0.825	0.000
M21.8 Other specified acquired deformities of limbs	0.174	0.825	0.000
M21.7 Unequal limb length (acquired)	0.174	0.825	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.174	0.826	0.000
M46.8 Other specified inflammatory spondylopathies	0.174	0.826	0.000
M46.5 Other infective spondylopathies	0.174	0.826	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.174	0.826	0.000
M46.2 Osteomyelitis of vertebra	0.174	0.826	0.000
M46.0 Spinal enthesopathy	0.174	0.826	0.000
M00.9 Pyogenic arthritis, unspecified	0.173	0.827	0.000
M94 Other disorders of cartilage	0.173	0.827	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.172	0.827	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.172	0.828	0.000
M14 Arthropathies in other diseases classified elsewhere	0.172	0.828	0.000
M90.7 Fracture of bone in neoplastic disease	0.172	0.828	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.171	0.829	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.171	0.829	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.171	0.829	0.000
M93 Other osteochondropathies	0.170	0.830	0.000
M86.8 Other osteomyelitis	0.170	0.830	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.170	0.830	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.170	0.830	0.000
M86.3 Chronic multifocal osteomyelitis	0.170	0.830	0.000
M86.2 Subacute osteomyelitis	0.170	0.830	0.000
M86.1 Other acute osteomyelitis	0.170	0.830	0.000
M86.0 Acute haematogenous osteomyelitis	0.170	0.830	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.170	0.830	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.170	0.830	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.170	0.830	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.170	0.830	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.170	0.830	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.170	0.830	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.170	0.830	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.170	0.830	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.170	0.830	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.170	0.830	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.169	0.830	0.000
M81.48 Drug-induced osteoporosis (Other)	0.169	0.830	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.169	0.830	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.169	0.830	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.169	0.830	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.169	0.830	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.169	0.830	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.169	0.830	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.169	0.830	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.169	0.831	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.169	0.831	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.169	0.831	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.169	0.831	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.169	0.831	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.169	0.831	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.169	0.831	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.169	0.831	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.169	0.831	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.169	0.831	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.169	0.831	0.000
M24.26 Disorder of ligament (Lower leg)	0.168	0.831	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.168	0.832	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.168	0.832	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.168	0.832	0.000
M67.1 Other contracture of tendon (sheath)	0.168	0.832	0.000
M88 Paget's disease of bone [osteitis deformans]	0.167	0.832	0.001
M34 Systemic sclerosis	0.167	0.832	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.167	0.833	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.167	0.833	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.167	0.833	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.167	0.833	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.167	0.833	0.000
M24.66 Ankylosis of joint (Lower leg)	0.166	0.833	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.166	0.834	0.000
M11 Other crystal arthropathies	0.166	0.834	0.000
M31.3 Wegener's granulomatosis	0.166	0.834	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.166	0.834	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.166	0.834	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.166	0.834	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.166	0.834	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.166	0.834	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.166	0.834	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.166	0.834	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.166	0.834	0.000
M89.59 Osteolysis (Site unspecified)	0.165	0.834	0.000
M89.58 Osteolysis (Other)	0.165	0.834	0.000
M89.57 Osteolysis (Ankle and foot)	0.165	0.834	0.000
M89.54 Osteolysis (Hand)	0.165	0.834	0.000
M89.53 Osteolysis (Forearm)	0.165	0.834	0.000
M89.52 Osteolysis (Upper arm)	0.165	0.834	0.000
M89.51 Osteolysis (Shoulder region)	0.165	0.834	0.000
M89.50 Osteolysis (Multiple sites)	0.165	0.834	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.165	0.835	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.165	0.835	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.165	0.835	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.164	0.835	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.164	0.835	0.000
M23.3 Other meniscus derangements	0.164	0.836	0.000
M24.21 Disorder of ligament (Shoulder region)	0.164	0.836	0.000
M54.4 Lumbago with sciatica	0.164	0.836	0.000
M85.0 Fibrous dysplasia (monostotic)	0.163	0.837	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.163	0.837	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.163	0.837	0.000
M67.4 Ganglion	0.163	0.837	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.162	0.837	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.162	0.838	0.000
M24.24 Disorder of ligament (Hand)	0.162	0.838	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.161	0.839	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.160	0.839	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.160	0.839	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.160	0.839	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.160	0.839	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.160	0.839	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.160	0.839	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.160	0.839	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.160	0.839	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.160	0.840	0.000
M65.3 Trigger finger	0.160	0.840	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.160	0.840	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.160	0.840	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.160	0.840	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.160	0.840	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.160	0.840	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.160	0.840	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.160	0.840	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.160	0.840	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.160	0.840	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.160	0.840	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.160	0.840	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.160	0.840	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.160	0.840	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.160	0.840	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.160	0.840	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.160	0.840	0.000
M90.6 Osteitis deformans in neoplastic disease	0.160	0.840	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.160	0.840	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.160	0.840	0.000
M90.3 Osteonecrosis in caisson disease	0.160	0.840	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.160	0.840	0.000
M90.0 Tuberculosis of bone	0.160	0.840	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.159	0.841	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.159	0.841	0.000
M92 Other juvenile osteochondrosis	0.159	0.841	0.000
M05 Seropositive rheumatoid arthritis	0.159	0.841	0.000
M21.6 Other acquired deformities of ankle and foot	0.158	0.842	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.158	0.842	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.158	0.842	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.158	0.842	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.158	0.842	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.157	0.843	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.157	0.843	0.000
M07.3 Other psoriatic arthropathies	0.157	0.843	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.157	0.843	0.000
M66.4 Spontaneous rupture of other tendons	0.157	0.843	0.000
M66.3 Spontaneous rupture of flexor tendons	0.157	0.843	0.000
M66.1 Rupture of synovium	0.157	0.843	0.000
M89.03 Algoneurodystrophy (Forearm)	0.157	0.843	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.156	0.844	0.000
M67.3 Transient synovitis	0.156	0.844	0.000
M67.0 Short Achilles tendon (acquired)	0.156	0.844	0.000
M81.2 Osteoporosis of disuse	0.156	0.844	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.156	0.844	0.000
M66.0 Rupture of popliteal cyst	0.155	0.845	0.000
M70-M79 Other soft tissue disorders	0.155	0.845	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.155	0.845	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.155	0.845	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.155	0.845	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.155	0.845	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.155	0.845	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.155	0.845	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.155	0.845	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.155	0.845	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.155	0.845	0.000
M83.9 Adult osteomalacia, unspecified	0.154	0.846	0.000
M83.8 Other adult osteomalacia	0.154	0.846	0.000
M83.5 Other drug-induced osteomalacia in adults	0.154	0.846	0.000
M83.4 Aluminum bone disease	0.154	0.846	0.000
M83.3 Adult osteomalacia due to malnutrition	0.154	0.846	0.000
M83.2 Adult osteomalacia due to malabsorption	0.154	0.846	0.000
M83.1 Senile osteomalacia	0.154	0.846	0.000
M83.0 Puerperal osteomalacia	0.154	0.846	0.000
M46.4 Discitis, unspecified	0.154	0.846	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.154	0.846	0.000
M24.29 Disorder of ligament (Site unspecified)	0.154	0.846	0.000
M24.28 Disorder of ligament (Other)	0.154	0.846	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.154	0.846	0.000
M24.22 Disorder of ligament (Upper arm)	0.154	0.846	0.000
M24.20 Disorder of ligament (Multiple sites)	0.154	0.846	0.000
M54.3 Sciatica	0.153	0.847	0.000
M84.4 Pathological fracture, not elsewhere classified	0.153	0.847	0.000
M12 Other specific arthropathies	0.153	0.847	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.153	0.847	0.000
M08 Juvenile arthritis	0.153	0.847	0.000
M21.2 Flexion deformity	0.153	0.847	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.153	0.847	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.152	0.848	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.152	0.848	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.152	0.848	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.152	0.848	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.152	0.848	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.152	0.848	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.152	0.848	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.152	0.848	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.152	0.848	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.152	0.848	0.000
M61 Calcification and ossification of muscle	0.152	0.848	0.000
M60 Myositis	0.152	0.848	0.000
M54.8 Other dorsalgia	0.152	0.848	0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.152	0.848	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.151	0.849	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.151	0.849	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.151	0.849	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.151	0.849	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.151	0.849	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.151	0.849	0.000
M43 Other deforming dorsopathies	0.151	0.849	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.150	0.849	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.150	0.849	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.150	0.849	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.150	0.849	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.150	0.849	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.150	0.849	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.150	0.849	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.150	0.849	0.000
M48.29 Kissing spine (Site unspecified)	0.150	0.849	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.27 Kissing spine (Lumbosacral region)	0.150	0.849	0.000
M48.26 Kissing spine (Lumbar region)	0.150	0.849	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.150	0.849	0.000
M48.24 Kissing spine (Thoracic region)	0.150	0.849	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.150	0.849	0.000
M48.22 Kissing spine (Cervical region)	0.150	0.849	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.150	0.849	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.150	0.849	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.150	0.849	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.150	0.849	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.150	0.849	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.150	0.849	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.150	0.849	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.150	0.849	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.150	0.849	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.150	0.849	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.150	0.849	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.150	0.849	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.150	0.849	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.150	0.849	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.150	0.849	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.150	0.849	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.150	0.849	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.150	0.849	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.150	0.849	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.150	0.849	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.150	0.849	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.150	0.849	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.150	0.849	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.150	0.849	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.150	0.849	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.150	0.849	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.150	0.849	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.150	0.849	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.150	0.849	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.150	0.849	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.150	0.849	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.150	0.849	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.150	0.849	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.150	0.849	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.150	0.849	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.150	0.850	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.150	0.850	0.000
M96.5 Postradiation scoliosis	0.150	0.850	0.000
M96.4 Postsurgical lordosis	0.150	0.850	0.000
M96.3 Postlaminectomy kyphosis	0.150	0.850	0.000
M96.2 Postradiation kyphosis	0.150	0.850	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.150	0.850	0.000
M50.9 Cervical disk disorder, unspecified	0.150	0.850	0.000
M50.8 Other cervical disk disorders	0.150	0.850	0.000
M53 Other dorsopathies, not elsewhere classified	0.149	0.851	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.149	0.851	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.149	0.851	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.149	0.851	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.149	0.851	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.149	0.851	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.149	0.851	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.149	0.851	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.149	0.851	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.149	0.851	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.149	0.851	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.149	0.851	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.149	0.851	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.149	0.851	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.149	0.851	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.149	0.851	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.149	0.851	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.149	0.851	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.149	0.851	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.149	0.851	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.149	0.851	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.149	0.851	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.149	0.851	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.149	0.851	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.149	0.851	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.149	0.851	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.149	0.851	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.149	0.851	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.149	0.851	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.149	0.851	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.149	0.851	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.149	0.851	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.149	0.851	0.000
M54.0 Panniculitis affecting regions of neck and back	0.148	0.852	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.148	0.852	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.148	0.852	0.000
M54.1 Radiculopathy	0.148	0.852	0.000
M23.4 Loose body in knee	0.146	0.854	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.146	0.854	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.146	0.854	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.146	0.854	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.146	0.854	0.000
M62 Other disorders of muscle	0.146	0.854	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.146	0.854	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.145	0.854	0.000
M32.8 Other forms of systemic lupus erythematosus	0.145	0.854	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations