TreeWAS – Variant ID: rs7573615

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I31.3 Pericardial effusion (noninflammatory)	0.043	0.957	0.000
I31 Other diseases of pericardium	0.038	0.962	0.000
I42 Cardiomyopathy	0.037	0.963	0.000
I42.0 Dilated cardiomyopathy	0.036	0.964	0.000
I30-I52 Other forms of heart disease	0.034	0.966	0.000
I44.7 Left bundle-branch block, unspecified	0.034	0.966	0.000
I44 Atrioventricular and left bundle-branch block	0.033	0.967	0.000
I38 Endocarditis, valve unspecified	0.032	0.968	0.000
I31.1 Chronic constrictive pericarditis	0.031	0.969	0.000
I40 Acute myocarditis	0.030	0.969	0.000
I42.8 Other cardiomyopathies	0.030	0.970	0.000
I42.6 Alcoholic cardiomyopathy	0.030	0.970	0.000
I44.3 Other and unspecified atrioventricular block	0.029	0.971	0.000
I42.2 Other hypertrophic cardiomyopathy	0.029	0.971	0.000
I42.9 Cardiomyopathy, unspecified	0.029	0.971	0.000
I49 Other cardiac arrhythmias	0.028	0.972	0.000
I37 Pulmonary valve disorders	0.028	0.972	0.000
I31.0 Chronic adhesive pericarditis	0.028	0.972	0.000
I40.0 Infective myocarditis	0.028	0.972	0.000
I31.8 Other specified diseases of pericardium	0.028	0.972	0.000
I31.2 Haemopericardium, not elsewhere classified	0.028	0.972	0.000
I49.9 Cardiac arrhythmia, unspecified	0.027	0.973	0.000
I31.9 Disease of pericardium, unspecified	0.027	0.973	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.027	0.973	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.026	0.973	0.000
I42.5 Other restrictive cardiomyopathy	0.026	0.973	0.000
I42.4 Endocardial fibroelastosis	0.026	0.973	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.026	0.973	0.000
I30 Acute pericarditis	0.026	0.974	0.000
I50 Heart failure	0.026	0.974	0.000
I44.6 Other and unspecified fascicular block	0.025	0.974	0.000
I50.0 Congestive heart failure	0.025	0.975	0.000
I44.4 Left anterior fascicular block	0.025	0.975	0.000
I52 Other heart disorders in diseases classified elsewhere	0.025	0.975	0.000
I48 Atrial fibrillation and flutter	0.025	0.975	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.025	0.975	0.000
I41 Myocarditis in diseases classified elsewhere	0.025	0.975	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.025	0.975	0.000
I32 Pericarditis in diseases classified elsewhere	0.025	0.975	0.000
I49.0 Ventricular fibrillation and flutter	0.024	0.976	0.000
I37.1 Pulmonary valve insufficiency	0.024	0.976	0.000
I44.5 Left posterior fascicular block	0.024	0.976	0.000
I36 Nonrheumatic tricuspid valve disorders	0.024	0.976	0.000
I44.1 Atrioventricular block, second degree	0.023	0.977	0.000
I40.9 Acute myocarditis, unspecified	0.022	0.978	0.000
I40.8 Other acute myocarditis	0.022	0.978	0.000
I40.1 Isolated myocarditis	0.022	0.978	0.000
I33 Acute and subacute endocarditis	0.022	0.978	0.000
I30.1 Infective pericarditis	0.021	0.979	0.000
I49.8 Other specified cardiac arrhythmias	0.021	0.979	0.000
I49.2 Junctional premature depolarisation	0.021	0.979	0.000
I49.1 Atrial premature depolarisation	0.021	0.979	0.000
I37.9 Pulmonary valve disorder, unspecified	0.020	0.979	0.000
I37.8 Other pulmonary valve disorders	0.020	0.979	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.020	0.979	0.000
I37.0 Pulmonary valve stenosis	0.020	0.979	0.000
I30.8 Other forms of acute pericarditis	0.019	0.981	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.019	0.981	0.000
I30.9 Acute pericarditis, unspecified	0.019	0.981	0.000
M81.98 Osteoporosis, unspecified (Other)	0.019	0.981	0.000
I49.4 Other and unspecified premature depolarisation	0.019	0.981	0.000
I49.5 Sick sinus syndrome	0.018	0.982	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.018	0.982	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.018	0.982	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.018	0.982	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.018	0.982	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.018	0.982	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.018	0.982	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.018	0.982	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.018	0.982	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.018	0.982	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.018	0.982	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.018	0.982	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.018	0.982	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.018	0.982	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.018	0.982	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.018	0.982	0.000
I48.4 Atypical atrial flutter	0.018	0.982	0.000
I48.3 Typical atrial flutter	0.018	0.982	0.000
I48.2 Chronic atrial fibrillation	0.018	0.982	0.000
I48.1 Persistent atrial fibrillation	0.018	0.982	0.000
I48.0 Paroxysmal atrial fibrillation	0.018	0.982	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.018	0.982	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.018	0.982	0.000
I51 Complications and ill-defined descriptions of heart disease	0.018	0.982	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.017	0.983	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.017	0.983	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.017	0.983	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.017	0.983	0.000
I51.4 Myocarditis, unspecified	0.017	0.983	0.000
M81.9 Osteoporosis, unspecified	0.016	0.984	0.000
I33.9 Acute endocarditis, unspecified	0.016	0.984	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.016	0.984	0.000
I34 Nonrheumatic mitral valve disorders	0.016	0.984	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.015	0.985	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.985	0.015
I47 Paroxysmal tachycardia	0.015	0.985	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.014	0.986	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.013	0.986	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.013	0.987	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.013	0.987	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.013	0.987	0.000
I33.0 Acute and subacute infective endocarditis	0.013	0.987	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.013	0.987	0.000
I51.5 Myocardial degeneration	0.013	0.987	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.013	0.987	0.000
I50.9 Heart failure, unspecified	0.013	0.987	0.000
I51.0 Cardiac septal defect, acquired	0.013	0.987	0.000
I51.9 Heart disease, unspecified	0.012	0.988	0.000
I35 Nonrheumatic aortic valve disorders	0.012	0.988	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.012	0.988	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.012	0.988	0.000
I51.8 Other ill-defined heart diseases	0.012	0.988	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.012	0.988	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.011	0.988	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.011	0.989	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.011	0.989	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.011	0.989	0.000
I51.6 Cardiovascular disease, unspecified	0.010	0.989	0.000
I47.0 Reentry ventricular arrhythmia	0.010	0.990	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.991	0.009
I46 Cardiac arrest	0.009	0.991	0.000
N02.9 Unspecified	0.009	0.991	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.991	0.009
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.991	0.009
M81 Osteoporosis without pathological fracture	0.009	0.991	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.992	0.008
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.992	0.008
I34.1 Mitral (valve) prolapse	0.008	0.992	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.992	0.008
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.992	0.008
I49.3 Ventricular premature depolarisation	0.008	0.992	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.992	0.008
I45 Other conduction disorders	0.008	0.992	0.000
I44.0 Atrioventricular block, first degree	0.008	0.992	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.992	0.008
M81.2 Osteoporosis of disuse	0.007	0.993	0.000
I50.1 Left ventricular failure	0.007	0.993	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.993	0.007
M20.2 Hallux rigidus	0.007	0.993	0.000
K56.2 Volvulus	0.007	0.993	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.993	0.007
I35.8 Other aortic valve disorders	0.007	0.993	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.993	0.007
I46.1 Sudden cardiac death, so described	0.006	0.993	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.993	0.007
Y42.4 Oral contraceptives	0.000	0.993	0.007
Y42.2 Antithyroid drugs	0.000	0.993	0.007
T83.2 Mechanical complication of graft of urinary organ	0.000	0.993	0.006
M81.20 Osteoporosis of disuse (Multiple sites)	0.006	0.993	0.000
I35.1 Aortic (valve) insufficiency	0.006	0.993	0.000
M81.0 Postmenopausal osteoporosis	0.006	0.993	0.000
M81.8 Other osteoporosis	0.006	0.994	0.000
M81.6 Localised osteoporosis [Lequesne]	0.006	0.994	0.000
M81.5 Idiopathic osteoporosis	0.006	0.994	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.006	0.994	0.000
M81.1 Postoophorectomy osteoporosis	0.006	0.994	0.000
I35.9 Aortic valve disorder, unspecified	0.006	0.994	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.994	0.006
I45.9 Conduction disorder, unspecified	0.006	0.994	0.000
I45.4 Nonspecific intraventricular block	0.006	0.994	0.000
I45.0 Right fascicular block	0.006	0.994	0.000
I44.2 Atrioventricular block, complete	0.006	0.994	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.994	0.006
I45.8 Other specified conduction disorders	0.005	0.994	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.005	0.994	0.000
M81.28 Osteoporosis of disuse (Other)	0.005	0.994	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.005	0.994	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.005	0.994	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.005	0.994	0.000
M81.24 Osteoporosis of disuse (Hand)	0.005	0.994	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.005	0.994	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.005	0.994	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.005	0.994	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.994	0.005
R35 Polyuria	0.000	0.994	0.006
I47.1 Supraventricular tachycardia	0.006	0.994	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.994	0.006
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.994	0.005
I45.2 Bifascicular block	0.005	0.995	0.000
M81.4 Drug-induced osteoporosis	0.005	0.995	0.000
H90.2 Conductive hearing loss, unspecified	0.005	0.995	0.000
I45.3 Trifascicular block	0.005	0.995	0.000
N02 Recurrent and persistent haematuria	0.005	0.995	0.000
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
H92.1 Otorrhoea	0.005	0.995	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
R90.0 Intracranial space-occupying lesion	0.005	0.995	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.005	0.995	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.005	0.995	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.005	0.995	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.005	0.995	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.005	0.995	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.005	0.995	0.000
I45.5 Other specified heart block	0.005	0.995	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.005	0.995	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.005	0.995	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.005	0.995	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.005	0.995	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.005	0.995	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.005	0.995	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.005	0.995	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.005	0.995	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.005	0.995	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.005	0.995	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.58 Idiopathic osteoporosis (Other)	0.005	0.995	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.005	0.995	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.005	0.995	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.005	0.995	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.005	0.995	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.005	0.995	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.005	0.995	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.005	0.995	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.005	0.995	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.005	0.995	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.005	0.995	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.005	0.995	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.005	0.995	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.005	0.995	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.005	0.995	0.000
M81.89 Other osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.88 Other osteoporosis (Other)	0.005	0.995	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.86 Other osteoporosis (Lower leg)	0.005	0.995	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.84 Other osteoporosis (Hand)	0.005	0.995	0.000
M81.83 Other osteoporosis (Forearm)	0.005	0.995	0.000
M81.82 Other osteoporosis (Upper arm)	0.005	0.995	0.000
M81.81 Other osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.80 Other osteoporosis (Multiple sites)	0.005	0.995	0.000
I45.1 Other and unspecified right bundle-branch block	0.005	0.995	0.000
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.005	0.995	0.000
C44.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
H90 Conductive and sensorineural hearing loss	0.004	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.004	0.996	0.000
N05 Unspecified nephritic syndrome	0.004	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
N05.1 Focal and segmental glomerular lesions	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.004	0.996	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.004	0.996	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.004	0.996	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.004	0.996	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.004	0.996	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.004	0.996	0.000
E07.9 Disorder of thyroid, unspecified	0.004	0.996	0.000
K56.4 Other impaction of intestine	0.004	0.996	0.000
N00-N08 Glomerular diseases	0.004	0.996	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.004	0.996	0.000
N02.6 Dense deposit disease	0.004	0.996	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.996	0.000
N02.2 Diffuse membranous glomerulonephritis	0.004	0.996	0.000
N02.1 Focal and segmental glomerular lesions	0.004	0.996	0.000
N02.0 Minor glomerular abnormality	0.004	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.004	0.996	0.000
N05.8 Other	0.004	0.996	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.996	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.004	0.996	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.996	0.004
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
N04 Nephrotic syndrome	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.004	0.996	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.004	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.996	0.000
F05.9 Delirium, unspecified	0.000	0.996	0.004
K75.4 Autoimmune hepatitis	0.000	0.996	0.003
N05.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N04.0 Minor glomerular abnormality	0.003	0.997	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
N05.9 Unspecified	0.003	0.997	0.000
N05.6 Dense deposit disease	0.003	0.997	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
N05.0 Minor glomerular abnormality	0.003	0.997	0.000
E07 Other disorders of thyroid	0.003	0.997	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
R41.1 Anterograde amnesia	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.003	0.997	0.000
N06 Isolated proteinuria with specified morphological lesion	0.003	0.997	0.000
N03 Chronic nephritic syndrome	0.003	0.997	0.000
N01 Rapidly progressive nephritic syndrome	0.003	0.997	0.000
N00 Acute nephritic syndrome	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
I45.6 Preexcitation syndrome	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.997	0.003
O32.1 Maternal care for breech presentation	0.003	0.997	0.000
H93.1 Tinnitus	0.003	0.997	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
N04.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.997	0.000
K56.7 Ileus, unspecified	0.003	0.997	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
N04.8 Other	0.003	0.997	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N04.6 Dense deposit disease	0.003	0.997	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.997	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
N04.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S93.4 Sprain and strain of ankle	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.003	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.000	0.997	0.003
O32.0 Maternal care for unstable lie	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.003	0.997	0.000
R41.3 Other amnesia	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
N05.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
N03.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.000	0.997	0.003
N08 Glomerular disorders in diseases classified elsewhere	0.003	0.997	0.000
N04.9 Unspecified	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
K56.3 Gallstone ileus	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.002	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.997	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
I86.1 Scrotal varices	0.000	0.997	0.003
N00.9 Unspecified	0.002	0.997	0.000
N00.8 Other	0.002	0.997	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N00.6 Dense deposit disease	0.002	0.997	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N00.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N00.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N00.0 Minor glomerular abnormality	0.002	0.997	0.000
N01.9 Unspecified	0.002	0.997	0.000
N01.8 Other	0.002	0.997	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N01.6 Dense deposit disease	0.002	0.997	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N01.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N01.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N01.0 Minor glomerular abnormality	0.002	0.997	0.000
N03.8 Other	0.002	0.997	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N03.6 Dense deposit disease	0.002	0.997	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N03.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N03.0 Minor glomerular abnormality	0.002	0.997	0.000
N06.9 Unspecified	0.002	0.997	0.000
N06.8 Other	0.002	0.997	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N06.6 Dense deposit disease	0.002	0.997	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N06.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N06.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N06.0 Minor glomerular abnormality	0.002	0.997	0.000
N07.9 Unspecified	0.002	0.997	0.000
N07.8 Other	0.002	0.997	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N07.6 Dense deposit disease	0.002	0.997	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N07.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N07.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N07.0 Minor glomerular abnormality	0.002	0.997	0.000
S92.51 Fracture of other toe (open)	0.002	0.997	0.000
H93.3 Disorders of acoustic nerve	0.002	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.002	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.002	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
K56.1 Intussusception	0.002	0.998	0.000
K22.7 Barrett's oesophagus	0.000	0.998	0.002
R41.0 Disorientation, unspecified	0.002	0.998	0.000
E00-E07 Disorders of thyroid gland	0.002	0.998	0.000
N02.8 Other	0.002	0.998	0.000
K56.0 Paralytic ileus	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
I51.7 Cardiomegaly	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
C62.9 Testis, unspecified	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
N08.8 Glomerular disorders in other diseases classified elsewhere	0.002	0.998	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.002	0.998	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.002	0.998	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
M31.6 Other giant cell arteritis	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations