TreeWAS – Variant ID: rs7586110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E80.4 Gilbert's syndrome	1.000	0.000	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.842	0.158	0.000
E80.6 Other disorders of bilirubin metabolism	0.813	0.187	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.680	0.320	0.000
E80.5 Crigler-Najjar syndrome	0.604	0.396	0.000
E80.3 Defects of catalase and peroxydase	0.604	0.396	0.000
E80.0 Hereditary erythropoietic porphyria	0.604	0.396	0.000
E80.2 Other porphyria	0.538	0.461	0.000
E80.1 Porphyria cutanea tarda	0.521	0.479	0.000
L42 Pityriasis rosea	0.064	0.936	0.000
E70-E90 Metabolic disorders	0.051	0.949	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.046	0.954	0.000
E88 Other metabolic disorders	0.044	0.956	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.043	0.957	0.000
E70 Disorders of aromatic amino-acid metabolism	0.040	0.960	0.000
E84 Cystic fibrosis	0.040	0.960	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.039	0.961	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.038	0.962	0.000
E87.5 Hyperkalaemia	0.038	0.962	0.000
E85 Amyloidosis	0.038	0.962	0.000
E74 Other disorders of carbohydrate metabolism	0.037	0.963	0.000
E87.7 Fluid overload	0.037	0.963	0.000
E77 Disorders of glycoprotein metabolism	0.036	0.963	0.000
E76 Disorders of glycosaminoglycan metabolism	0.036	0.963	0.000
E72 Other disorders of amino-acid metabolism	0.036	0.963	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.036	0.963	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.036	0.963	0.000
E87.0 Hyperosmolality and hypernatraemia	0.036	0.964	0.000
E78.4 Other hyperlipidaemia	0.035	0.965	0.000
E79 Disorders of purine and pyrimidine metabolism	0.034	0.966	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.033	0.967	0.000
E70.3 Albinism	0.032	0.968	0.000
E84.9 Cystic fibrosis, unspecified	0.032	0.968	0.000
E88.9 Metabolic disorder, unspecified	0.031	0.968	0.000
E75.5 Other lipid storage disorders	0.030	0.970	0.000
E85.9 Amyloidosis, unspecified	0.029	0.971	0.000
E88.2 Lipomatosis, not elsewhere classified	0.029	0.971	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.029	0.971	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.029	0.971	0.000
E70.2 Disorders of tyrosine metabolism	0.029	0.971	0.000
E70.1 Other hyperphenylalaninaemias	0.029	0.971	0.000
E70.0 Classical phenylketonuria	0.029	0.971	0.000
E88.3 Tumour lysis syndrome	0.029	0.971	0.000
E84.8 Cystic fibrosis with other manifestations	0.029	0.971	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.029	0.971	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.029	0.971	0.000
E73 Lactose intolerance	0.028	0.971	0.000
E87.4 Mixed disorder of acid-base balance	0.028	0.972	0.000
E75.6 Lipid storage disorder, unspecified	0.028	0.972	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.028	0.972	0.000
E75.3 Sphingolipidosis, unspecified	0.028	0.972	0.000
E75.2 Other sphingolipidosis	0.028	0.972	0.000
E75.1 Other gangliosidosis	0.028	0.972	0.000
E75.0 GM2 gangliosidosis	0.028	0.972	0.000
E85.3 Secondary systemic amyloidosis	0.027	0.973	0.000
E88.8 Other specified metabolic disorders	0.027	0.973	0.000
E85.8 Other amyloidosis	0.027	0.973	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.027	0.973	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.027	0.973	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.027	0.973	0.000
I38 Endocarditis, valve unspecified	0.000	0.973	0.027
E74.3 Other disorders of intestinal carbohydrate absorption	0.027	0.973	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.027	0.973	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.027	0.973	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.027	0.973	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.027	0.973	0.000
E74.2 Disorders of galactose metabolism	0.027	0.973	0.000
E74.1 Disorders of fructose metabolism	0.027	0.973	0.000
E74.0 Glycogen storage disease	0.027	0.973	0.000
E71.3 Disorders of fatty-acid metabolism	0.026	0.973	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.026	0.973	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.026	0.973	0.000
E71.0 Maple-syrup-urine disease	0.026	0.973	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.026	0.973	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.026	0.973	0.000
E72.5 Disorders of glycine metabolism	0.026	0.973	0.000
E72.4 Disorders of ornithine metabolism	0.026	0.973	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.026	0.973	0.000
E72.2 Disorders of urea cycle metabolism	0.026	0.973	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.026	0.973	0.000
E72.0 Disorders of amino-acid transport	0.026	0.973	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.026	0.973	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.026	0.973	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.026	0.973	0.000
E76.2 Other mucopolysaccharidoses	0.026	0.973	0.000
E76.1 Mucopolysaccharidosis, type II	0.026	0.973	0.000
E76.0 Mucopolysaccharidosis, type I	0.026	0.973	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.026	0.973	0.000
E77.8 Other disorders of glycoprotein metabolism	0.026	0.973	0.000
E77.1 Defects in glycoprotein degradation	0.026	0.973	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.026	0.973	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.026	0.974	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.026	0.974	0.000
E78.1 Pure hyperglyceridaemia	0.026	0.974	0.000
E85.4 Organ-limited amyloidosis	0.025	0.975	0.000
E87.6 Hypokalaemia	0.025	0.975	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.024	0.975	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.024	0.975	0.000
E79.1 Lesch-Nyhan syndrome	0.024	0.975	0.000
E78.3 Hyperchylomicronaemia	0.024	0.976	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.022	0.978	0.000
E73.8 Other lactose intolerance	0.021	0.979	0.000
E73.1 Secondary lactase deficiency	0.021	0.979	0.000
E73.0 Congenital lactase deficiency	0.021	0.979	0.000
E78.2 Mixed hyperlipidaemia	0.021	0.979	0.000
E78.6 Lipoprotein deficiency	0.020	0.980	0.000
D18.0 Haemangioma, any site	0.019	0.981	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.982	0.018
E78.8 Other disorders of lipoprotein metabolism	0.018	0.982	0.000
E87.3 Alkalosis	0.015	0.984	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.013	0.987	0.000
R17 Unspecified jaundice	0.013	0.987	0.000
E73.9 Lactose intolerance, unspecified	0.012	0.987	0.000
K50.0 Crohn's disease of small intestine	0.000	0.988	0.012
D18 Haemangioma and lymphangioma, any site	0.011	0.989	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.010	0.990	0.000
L40-L45 Papulosquamous disorders	0.010	0.990	0.000
E89.2 Postprocedural hypoparathyroidism	0.010	0.990	0.000
D18.1 Lymphangioma, any site	0.010	0.990	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.010	0.990	0.000
E89.5 Postprocedural testicular hypofunction	0.010	0.990	0.000
E89.1 Postprocedural hypoinsulinaemia	0.009	0.990	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.009	0.991	0.000
E89.4 Postprocedural ovarian failure	0.008	0.992	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.008	0.992	0.000
E89.3 Postprocedural hypopituitarism	0.008	0.992	0.000
K50.9 Crohn's disease, unspecified	0.000	0.992	0.008
R61 Hyperhidrosis	0.000	0.992	0.008
K50 Crohn's disease [regional enteritis]	0.000	0.993	0.007
L44 Other papulosquamous disorders	0.007	0.993	0.000
L41 Parapsoriasis	0.007	0.993	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.007	0.993	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.007	0.993	0.000
H54.9 Unspecified visual impairment (binocular)	0.007	0.993	0.000
L43 Lichen planus	0.006	0.994	0.000
E83 Disorders of mineral metabolism	0.006	0.994	0.000
R61.0 Localised hyperhidrosis	0.000	0.994	0.006
R61.1 Generalised hyperhidrosis	0.000	0.994	0.006
E78.5 Hyperlipidaemia, unspecified	0.006	0.994	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
L41.9 Parapsoriasis, unspecified	0.005	0.994	0.000
L41.8 Other parapsoriasis	0.005	0.994	0.000
L41.5 Retiform parapsoriasis	0.005	0.994	0.000
L41.4 Large plaque parapsoriasis	0.005	0.994	0.000
L41.3 Small plaque parapsoriasis	0.005	0.994	0.000
L41.2 Lymphomatoid papulosis	0.005	0.994	0.000
L41.1 Pityriasis lichenoides chronica	0.005	0.994	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.005	0.994	0.000
L44.9 Papulosquamous disorder, unspecified	0.005	0.994	0.000
L44.8 Other specified papulosquamous disorders	0.005	0.994	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.005	0.994	0.000
L44.3 Lichen ruber moniliformis	0.005	0.994	0.000
L44.2 Lichen striatus	0.005	0.994	0.000
L44.1 Lichen nitidus	0.005	0.994	0.000
L44.0 Pityriasis rubra pilaris	0.005	0.994	0.000
E87.2 Acidosis	0.005	0.995	0.000
K50.8 Other Crohn's disease	0.000	0.995	0.005
F33.9 Recurrent depressive disorder, unspecified	0.005	0.995	0.000
L43.3 Subacute (active) lichen planus	0.005	0.995	0.000
L43.2 Lichenoid drug reaction	0.005	0.995	0.000
L43.1 Bullous lichen planus	0.005	0.995	0.000
L43.0 Hypertrophic lichen planus	0.005	0.995	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.005	0.995	0.000
E83.8 Other disorders of mineral metabolism	0.005	0.995	0.000
E83.2 Disorders of zinc metabolism	0.005	0.995	0.000
E83.0 Disorders of copper metabolism	0.005	0.995	0.000
K11.5 Sialolithiasis	0.005	0.995	0.000
F31 Bipolar affective disorder	0.005	0.995	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.005	0.995	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.005	0.995	0.000
E83.3 Disorders of phosphorus metabolism	0.005	0.995	0.000
F34.1 Dysthymia	0.005	0.995	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.004	0.995	0.000
F34 Persistent mood [affective] disorders	0.004	0.995	0.000
F30-F39 Mood [affective] disorders	0.005	0.995	0.000
L43.9 Lichen planus, unspecified	0.004	0.996	0.000
F32.0 Mild depressive episode	0.004	0.996	0.000
N48.4 Impotence of organic origin	0.004	0.996	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.996	0.004
L43.8 Other lichen planus	0.004	0.996	0.000
F30 Manic episode	0.004	0.996	0.000
F30.2 Mania with psychotic symptoms	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.004	0.996	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.004	0.996	0.000
F52.2 Failure of genital response	0.004	0.996	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.004	0.996	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.004	0.996	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.004	0.996	0.000
Y79.0 Diagnostic and monitoring devices	0.004	0.996	0.000
F30.1 Mania without psychotic symptoms	0.004	0.996	0.000
F34.0 Cyclothymia	0.003	0.996	0.000
E83.4 Disorders of magnesium metabolism	0.003	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.996	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.996	0.000
F38 Other mood [affective] disorders	0.003	0.996	0.000
F39 Unspecified mood [affective] disorder	0.003	0.996	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.003	0.996	0.000
F33.8 Other recurrent depressive disorders	0.003	0.996	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
F30.8 Other manic episodes	0.003	0.997	0.000
F30.0 Hypomania	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
F52 Sexual dysfunction, not caused by organic disorder or disease	0.003	0.997	0.000
F52.0 Lack or loss of sexual desire	0.003	0.997	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.003	0.997	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.997	0.003
F33.0 Recurrent depressive disorder, current episode mild	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
F32 Depressive episode	0.003	0.997	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.003	0.997	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F38.8 Other specified mood [affective] disorders	0.003	0.997	0.000
F38.1 Other recurrent mood [affective] disorders	0.003	0.997	0.000
F38.0 Other single mood [affective] disorders	0.003	0.997	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.003	0.997	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.003	0.997	0.000
F32.8 Other depressive episodes	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
I83.1 Varicose veins of lower extremities with inflammation	0.003	0.997	0.000
A49.8 Other bacterial infections of unspecified site	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.997	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.997	0.000
F52.7 Excessive sexual drive	0.002	0.997	0.000
F52.6 Nonorganic dyspareunia	0.002	0.997	0.000
F52.5 Nonorganic vaginismus	0.002	0.997	0.000
F52.4 Premature ejaculation	0.002	0.997	0.000
F52.3 Orgasmic dysfunction	0.002	0.997	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
C32.0 Glottis	0.000	0.997	0.003
O00.1 Tubal pregnancy	0.003	0.997	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.997	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.003	0.997	0.000
Y80 Physical medicine devices associated with adverse incidents	0.002	0.997	0.000
Y78 Radiological devices associated with adverse incidents	0.002	0.997	0.000
Y75 Neurological devices associated with adverse incidents	0.002	0.997	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.002	0.997	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.002	0.997	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.002	0.997	0.000
T79.5 Traumatic anuria	0.002	0.997	0.000
J38.0 Paralysis of vocal cords and larynx	0.002	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.002	0.998	0.000
E86 Volume depletion	0.002	0.998	0.000
Y71.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y81.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y81.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y81.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y81.0 Diagnostic and monitoring devices	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.002	0.998	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
C50.1 Central portion of breast	0.002	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
Y82.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
Y82.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y82.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y82.0 Diagnostic and monitoring devices	0.002	0.998	0.000
O41.0 Oligohydramnios	0.000	0.998	0.002
Y71.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y71.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y71.0 Diagnostic and monitoring devices	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.000	0.998	0.002
T79.8 Other early complications of trauma	0.002	0.998	0.000
Y73.0 Diagnostic and monitoring devices	0.002	0.998	0.000
F50 Eating disorders	0.002	0.998	0.000
F50.9 Eating disorder, unspecified	0.002	0.998	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
Y70.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y70.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y70.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y70.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y70.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y72.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y72.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y72.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y72.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y72.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y74.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y74.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y74.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y74.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y74.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y75.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y75.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y75.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y75.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y75.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y78.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y78.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y78.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y78.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y78.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y80.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y80.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y80.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y80.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y80.0 Diagnostic and monitoring devices	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.002	0.998	0.000
F51 Nonorganic sleep disorders	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
Y73.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y73.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y73.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
Y76.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y76.0 Diagnostic and monitoring devices	0.002	0.998	0.000
H26.0 Infantile, juvenile and presenile cataract	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
C32 Malignant neoplasm of larynx	0.000	0.998	0.002
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.002	0.998	0.000
F51.5 Nightmares	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
F55 Abuse of non-dependence-producing substances	0.002	0.998	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
K10.2 Inflammatory conditions of jaws	0.000	0.998	0.002
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
F51.4 Sleep terrors [night terrors]	0.002	0.998	0.000
F50.8 Other eating disorders	0.002	0.998	0.000
F50.5 Vomiting associated with other psychological disturbances	0.002	0.998	0.000
F50.4 Overeating associated with other psychological disturbances	0.002	0.998	0.000
F50.3 Atypical bulimia nervosa	0.002	0.998	0.000
F50.1 Atypical anorexia nervosa	0.002	0.998	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
H52.2 Astigmatism	0.000	0.998	0.002
K10.0 Developmental disorders of jaws	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.000	0.998	0.002
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.002	0.998	0.000
F51.8 Other nonorganic sleep disorders	0.002	0.998	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.002	0.998	0.000
F51.1 Nonorganic hypersomnia	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
F51.3 Sleepwalking [somnambulism]	0.002	0.998	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.002	0.998	0.000
Y73.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
N48.1 Balanoposthitis	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.000	0.998	0.002
N30.9 Cystitis, unspecified	0.000	0.998	0.002
C51.9 Vulva, unspecified	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.998	0.002
K80 Cholelithiasis	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.001	0.998	0.000
F53.9 Puerperal mental disorder, unspecified	0.001	0.998	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.998	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.998	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
G06.0 Intracranial abscess and granuloma	0.000	0.998	0.002
N30.8 Other cystitis	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.000	0.998	0.002
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.998	0.001
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.998	0.001
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
F51.0 Nonorganic insomnia	0.001	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
H54.1 Blindness, one eye, low vision, other eye	0.001	0.998	0.000
N30.0 Acute cystitis	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.001
M17.1 Other primary gonarthrosis	0.002	0.998	0.000
H81 Disorders of vestibular function	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.001
H54.7 Unspecified visual loss	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.001
A49.1 Streptococcal infection, unspecified	0.001	0.998	0.000
C25.2 Tail of pancreas	0.000	0.998	0.001
C32.1 Supraglottis	0.000	0.998	0.001
A49 Bacterial infection of unspecified site	0.001	0.998	0.000
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
H54.5 Low vision, one eye	0.001	0.999	0.000
H81.8 Other disorders of vestibular function	0.000	0.999	0.001
H81.3 Other peripheral vertigo	0.000	0.999	0.001
O00.9 Ectopic pregnancy, unspecified	0.001	0.999	0.000
N48 Other disorders of penis	0.001	0.999	0.000
O00 Ectopic pregnancy	0.001	0.999	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.999	0.001
K80.3 Calculus of bile duct with cholangitis	0.001	0.999	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.999	0.001
N27.0 Small kidney, unilateral	0.001	0.999	0.000
W19.3 Sports and athletics area	0.000	0.999	0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.999	0.001
S64.4 Injury of digital nerve of other finger	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.999	0.001
E15 Nondiabetic hypoglycaemic coma	0.001	0.999	0.000
N70 Salpingitis and oophoritis	0.001	0.999	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.000	0.999	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
K10.3 Alveolitis of jaws	0.000	0.999	0.001
K10 Other diseases of jaws	0.000	0.999	0.001
L40 Psoriasis	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.001	0.999	0.000
B44.1 Other pulmonary aspergillosis	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.000	0.999	0.001
N27.9 Small kidney, unspecified	0.001	0.999	0.000
F80 Specific developmental disorders of speech and language	0.001	0.999	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.999	0.001
D10.0 Lip	0.000	0.999	0.001
H10.9 Conjunctivitis, unspecified	0.001	0.999	0.000
Y53.2 Stimulant laxatives	0.001	0.999	0.000
N30 Cystitis	0.000	0.999	0.001
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.999	0.001
A49.3 Mycoplasma infection, unspecified	0.001	0.999	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.001	0.999	0.000
O00.8 Other ectopic pregnancy	0.001	0.999	0.000
O00.2 Ovarian pregnancy	0.001	0.999	0.000
O00.0 Abdominal pregnancy	0.001	0.999	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.001	0.999	0.000
M48.02 Spinal stenosis (Cervical region)	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.000	0.999	0.001
M84.0 Malunion of fracture	0.000	0.999	0.001
Q62.5 Duplication of ureter	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
K11 Diseases of salivary glands	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.999	0.001
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.999	0.001
C81.9 Hodgkin's disease, unspecified	0.000	0.999	0.001
E28.3 Primary ovarian failure	0.001	0.999	0.000
F45.8 Other somatoform disorders	0.000	0.999	0.001
H52.3 Anisometropia and aniseikonia	0.000	0.999	0.001
H81.9 Disorder of vestibular function, unspecified	0.000	0.999	0.001
Z29 Need for other prophylactic measures	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations