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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7654585
log Bayes Factor = <0.0001
Chromosome 4   position 25,942,751  (GRCh37) Explore rs7654585 on Ensembl!
Variant rs7654585 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
O16 Unspecified maternal hypertension
0.000 0.965 0.035
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.000 0.966 0.034
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.000 0.969 0.031
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.000 0.970 0.030
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.000 0.970 0.030
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.000 0.971 0.029
O12.1 Gestational proteinuria
0.000 0.972 0.028
O14.0 Moderate preeclampsia
0.000 0.973 0.027
O15 Eclampsia
0.000 0.976 0.023
O14.9 Preeclampsia, unspecified
0.000 0.977 0.023
O12.0 Gestational oedema
0.000 0.978 0.022
O14.1 Severe preeclampsia
0.000 0.978 0.022
O14.2 HELLP syndrome
0.000 0.978 0.022
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.979 0.020
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.980 0.020
O12.2 Gestational oedema with proteinuria
0.000 0.980 0.020
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.980 0.020
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.980 0.020
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.981 0.019
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.981 0.019
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.982 0.018
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.982 0.018
T36 Poisoning by systemic antibiotics
0.000 0.982 0.018
T39.0 Salicylates
0.000 0.982 0.018
T46.1 Calcium-channel blockers
0.000 0.982 0.018
T40.2 Other opioids
0.000 0.983 0.017
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.983 0.017
O15.9 Eclampsia, unspecified as to time period
0.000 0.983 0.017
O15.1 Eclampsia in labour
0.000 0.983 0.017
O15.0 Eclampsia in pregnancy
0.000 0.983 0.017
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.983 0.017
T36.0 Penicillins
0.000 0.984 0.016
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.984 0.016
O15.2 Eclampsia in the puerperium
0.000 0.984 0.016
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.984 0.016
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.984 0.015
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.985 0.015
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.985 0.015
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.985 0.015
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.985 0.015
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
0.000 0.985 0.015
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.985 0.015
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.985 0.015
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.985 0.015
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.985 0.015
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.985 0.015
T44.0 Anticholinesterase agents
0.000 0.985 0.015
M16.1 Other primary coxarthrosis
0.000 0.985 0.015
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.985 0.015
T46.7 Peripheral vasodilators
0.000 0.985 0.015
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.986 0.014
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.986 0.014
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.986 0.014
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.986 0.014
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.986 0.014
T36.3 Macrolides
0.000 0.986 0.014
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.986 0.014
T36.4 Tetracyclines
0.000 0.986 0.014
H55 Nystagmus and other irregular eye movements
0.014 0.986 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.986 0.014
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.987 0.013
T40.1 Heroin
0.000 0.987 0.013
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.987 0.013
T36.8 Other systemic antibiotics
0.000 0.987 0.013
T36.9 Systemic antibiotic, unspecified
0.000 0.987 0.013
T36.7 Antifungal antibiotics, systemically used
0.000 0.987 0.013
T36.6 Rifamycins
0.000 0.987 0.013
T36.5 Aminoglycosides
0.000 0.987 0.013
T36.2 Chloramphenicol group
0.000 0.987 0.013
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.987 0.013
M16.0 Primary coxarthrosis, bilateral
0.000 0.987 0.013
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.987 0.013
T47.2 Stimulant laxatives
0.000 0.987 0.013
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.987 0.013
M16.7 Other secondary coxarthrosis
0.000 0.987 0.013
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.987 0.012
T40.8 Lysergide [LSD]
0.000 0.987 0.012
T40.7 Cannabis (derivatives)
0.000 0.987 0.012
T40.3 Methadone
0.000 0.987 0.012
T40.0 Opium
0.000 0.987 0.012
M16 Coxarthrosis [arthrosis of hip]
0.000 0.987 0.013
H59.8 Other postprocedural disorders of eye and adnexa
0.012 0.988 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.988 0.012
T39.4 Antirheumatics, not elsewhere classified
0.000 0.988 0.012
T39.2 Pyrazolone derivatives
0.000 0.988 0.012
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.988 0.012
T43.2 Other and unspecified antidepressants
0.000 0.988 0.012
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.988 0.012
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.988 0.012
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.988 0.011
T40.6 Other and unspecified narcotics
0.000 0.989 0.011
T47.6 Antidiarrhoeal drugs
0.000 0.989 0.011
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.989 0.011
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.989 0.011
T47.7 Emetics
0.000 0.989 0.011
T47.5 Digestants
0.000 0.989 0.011
T47.3 Saline and osmotic laxatives
0.000 0.989 0.011
T47.4 Other laxatives
0.000 0.989 0.011
T40.5 Cocaine
0.000 0.989 0.011
T42.1 Iminostilbenes
0.000 0.989 0.011
T47.0 Histamine H(2)-receptor antagonists
0.000 0.989 0.011
T42.0 Hydantoin derivatives
0.000 0.989 0.011
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.989 0.010
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.990 0.010
T37.5 Antiviral drugs
0.000 0.990 0.010
T37.4 Anthelminthics
0.000 0.990 0.010
T37.3 Other antiprotozoal drugs
0.000 0.990 0.010
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.990 0.010
T37.1 Antimycobacterial drugs
0.000 0.990 0.010
T37.0 Sulphonamides
0.000 0.990 0.010
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.990 0.010
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.010 0.990 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.990 0.010
T49.9 Topical agent, unspecified
0.000 0.990 0.010
T49.8 Other topical agents
0.000 0.990 0.010
T49.7 Dental drugs, topically applied
0.000 0.990 0.010
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.990 0.010
T49.5 Ophthalmological drugs and preparations
0.000 0.990 0.010
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.990 0.010
T49.3 Emollients, demulcents and protectants
0.000 0.990 0.010
T49.2 Local astringents and local detergents
0.000 0.990 0.010
T49.1 Antipruritics
0.000 0.990 0.010
T40.4 Other synthetic narcotics
0.000 0.990 0.010
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.010 0.990 0.000
T48.5 Anti-common-cold drugs
0.000 0.990 0.010
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.990 0.010
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.990 0.010
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.990 0.010
T48.4 Expectorants
0.000 0.990 0.010
T48.3 Antitussives
0.000 0.990 0.010
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.990 0.010
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.990 0.010
T48.0 Oxytocic drugs
0.000 0.990 0.010
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.000 0.990 0.010
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.990 0.010
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.990 0.010
T41.5 Therapeutic gases
0.000 0.990 0.010
T41.4 Anaesthetic, unspecified
0.000 0.990 0.010
T41.3 Local anaesthetics
0.000 0.990 0.010
T41.1 Intravenous anaesthetics
0.000 0.990 0.010
T41.0 Inhaled anaesthetics
0.000 0.990 0.010
T43.9 Psychotropic drug, unspecified
0.000 0.990 0.010
T42.3 Barbiturates
0.000 0.990 0.010
Z90.2 Acquired absence of lung [part of]
0.010 0.990 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.000 0.990 0.009
M16.4 Posttraumatic coxarthrosis, bilateral
0.000 0.991 0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.991 0.009
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.991 0.009
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.991 0.009
T42.2 Succinimides and oxazolidinediones
0.000 0.991 0.009
T41.2 Other and unspecified general anaesthetics
0.000 0.991 0.009
H55-H59 Other disorders of eye and adnexa
0.009 0.991 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.009 0.991 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.991 0.009
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.991 0.009
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.991 0.009
M48.09 Spinal stenosis (Site unspecified)
0.008 0.992 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.992 0.008
T43.6 Psychostimulants with abuse potential
0.000 0.992 0.008
M16.3 Other dysplastic coxarthrosis
0.000 0.992 0.008
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.008 0.992 0.000
M16.5 Other posttraumatic coxarthrosis
0.000 0.992 0.008
T50.4 Drugs affecting uric acid metabolism
0.000 0.992 0.007
T38.9 Other and unspecified hormone antagonists
0.000 0.992 0.007
T38.7 Androgens and anabolic congeners
0.000 0.992 0.007
T38.4 Oral contraceptives
0.000 0.992 0.007
T38.2 Antithyroid drugs
0.000 0.992 0.007
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.992 0.008
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.992 0.007
T50.8 Diagnostic agents
0.000 0.993 0.007
T38.0 Glucocorticoids and synthetic analogues
0.000 0.993 0.007
T50.7 Analeptics and opioid receptor antagonists
0.000 0.993 0.007
T50.5 Appetite depressants
0.000 0.993 0.007
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.993 0.007
T50.0 Mineralocorticoids and their antagonists
0.000 0.993 0.007
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.993 0.007
T45.8 Other primarily systemic and haematological agents
0.000 0.993 0.007
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.993 0.007
T45.6 Fibrinolysis-affecting drugs
0.000 0.993 0.007
T45.4 Iron and its compounds
0.000 0.993 0.007
T45.3 Enzymes, not elsewhere classified
0.000 0.993 0.007
T42.4 Benzodiazepines
0.000 0.993 0.007
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.993 0.007
T38.5 Other oestrogens and progestogens
0.000 0.993 0.007
T50.1 Loop [high-ceiling] diuretics
0.000 0.993 0.007
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.993 0.007
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.993 0.007
K63.8 Other specified diseases of intestine
0.000 0.993 0.007
T45.5 Anticoagulants
0.000 0.993 0.007
H59.0 Vitreous syndrome following cataract surgery
0.007 0.993 0.000
M48.0 Spinal stenosis
0.007 0.993 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.993 0.007
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.993 0.006
T38.1 Thyroid hormones and substitutes
0.000 0.993 0.006
T45.2 Vitamins, not elsewhere classified
0.000 0.993 0.006
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.006 0.994 0.000
N21.0 Calculus in bladder
0.000 0.994 0.006
T45.0 Antiallergic and antiemetic drugs
0.000 0.994 0.005
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.005 0.994 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.005 0.995 0.000
T39.1 4-Aminophenol derivatives
0.000 0.995 0.005
M48.03 Spinal stenosis (Cervicothoracic region)
0.005 0.995 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.005 0.995 0.000
Q61.0 Congenital single renal cyst
0.000 0.995 0.005
H95.1 Other disorders following mastoidectomy
0.005 0.995 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.005 0.995 0.000
M48.04 Spinal stenosis (Thoracic region)
0.005 0.995 0.000
M48 Other spondylopathies
0.005 0.995 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.005 0.995 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.005 0.995 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.995 0.005
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.005 0.995 0.000
H92.1 Otorrhoea
0.004 0.996 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.004 0.996 0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere
0.004 0.996 0.000
H58.1 Visual disturbances in diseases classified elsewhere
0.004 0.996 0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere
0.004 0.996 0.000
H90.0 Conductive hearing loss, bilateral
0.004 0.996 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.000 0.996 0.004
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.004 0.996 0.000
M48.8 Other specified spondylopathies
0.004 0.996 0.000
H92 Otalgia and effusion of ear
0.004 0.996 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.004 0.996 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.004 0.996 0.000
Q21.1 Atrial septal defect
0.000 0.996 0.004
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M48.4 Fatigue fracture of vertebra
0.004 0.996 0.000
M48.3 Traumatic spondylopathy
0.004 0.996 0.000
M48.2 Kissing spine
0.004 0.996 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.004 0.996 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.004 0.996 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.004 0.996 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.004 0.996 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.004 0.996 0.000
H90-H95 Other disorders of ear
0.004 0.996 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.004 0.996 0.000
N60.8 Other benign mammary dysplasias
0.000 0.996 0.004
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.003 0.996 0.000
I87.1 Compression of vein
0.000 0.997 0.003
H57 Other disorders of eye and adnexa
0.003 0.997 0.000
G50.0 Trigeminal neuralgia
0.003 0.997 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.003 0.997 0.000
C90.0 Multiple myeloma
0.000 0.997 0.003
K81.0 Acute cholecystitis
0.000 0.997 0.003
H90 Conductive and sensorineural hearing loss
0.003 0.997 0.000
H90.5 Sensorineural hearing loss, unspecified
0.003 0.997 0.000
H95.8 Other postprocedural disorders of ear and mastoid process
0.003 0.997 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.003 0.997 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.003 0.997 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.003 0.997 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.003 0.997 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.003 0.997 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.003 0.997 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.003 0.997 0.000
D26.0 Cervix uteri
0.003 0.997 0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.003 0.997 0.000
H91.3 Deaf mutism, not elsewhere classified
0.003 0.997 0.000
H91.8 Other specified hearing loss
0.003 0.997 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.003 0.997 0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.003 0.997 0.000
T17.2 Foreign body in pharynx
0.000 0.997 0.003
M48.9 Spondylopathy, unspecified
0.003 0.997 0.000
H91 Other hearing loss
0.003 0.997 0.000
D86 Sarcoidosis
0.003 0.997 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.003 0.997 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.003 0.997 0.000
D26.1 Corpus uteri
0.003 0.997 0.000
D84.9 Immunodeficiency, unspecified
0.003 0.997 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.003 0.997 0.000
M54.16 Radiculopathy (Lumbar region)
0.000 0.997 0.003
H92.2 Otorrhagia
0.003 0.997 0.000
D84 Other immunodeficiencies
0.003 0.997 0.000
D80 Immunodeficiency with predominantly antibody defects
0.003 0.997 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.003 0.997 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.003 0.997 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.003 0.997 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.003 0.997 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.003 0.997 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.003 0.997 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.003 0.997 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.003 0.997 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.003 0.997 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.003 0.997 0.000
M48.29 Kissing spine (Site unspecified)
0.003 0.997 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M48.27 Kissing spine (Lumbosacral region)
0.003 0.997 0.000
M48.26 Kissing spine (Lumbar region)
0.003 0.997 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.003 0.997 0.000
M48.24 Kissing spine (Thoracic region)
0.003 0.997 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.003 0.997 0.000
M48.22 Kissing spine (Cervical region)
0.003 0.997 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.003 0.997 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.003 0.997 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.003 0.997 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.003 0.997 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.003 0.997 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.003 0.997 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.003 0.997 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.003 0.997 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.003 0.997 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.003 0.997 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.003 0.997 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.003 0.997 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.003 0.997 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.003 0.997 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.003 0.997 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.003 0.997 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.003 0.997 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.003 0.997 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.003 0.997 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.003 0.997 0.000
D86.1 Sarcoidosis of lymph nodes
0.003 0.997 0.000
H92.0 Otalgia
0.003 0.997 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.003 0.997 0.000
D86.0 Sarcoidosis of lung
0.003 0.997 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.997 0.003
D80-D89 Certain disorders involving the immune mechanism
0.003 0.997 0.000
S42.00 Fracture of clavicle (closed)
0.003 0.997 0.000
D12.4 Descending colon
0.003 0.997 0.000
D84.1 Defects in the complement system
0.003 0.997 0.000
D86.8 Sarcoidosis of other and combined sites
0.003 0.997 0.000
R25.1 Tremor, unspecified
0.003 0.997 0.000
H90.3 Sensorineural hearing loss, bilateral
0.003 0.997 0.000
H91.1 Presbycusis
0.003 0.997 0.000
N90.7 Vulvar cyst
0.000 0.997 0.003
D86.3 Sarcoidosis of skin
0.003 0.997 0.000
G24.8 Other dystonia
0.003 0.997 0.000
G62.8 Other specified polyneuropathies
0.000 0.997 0.003
H57.0 Anomalies of pupillary function
0.002 0.997 0.000
I84.2 Internal haemorrhoids without complication
0.003 0.997 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.002 0.997 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.002 0.997 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.002 0.997 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.002 0.997 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.002 0.997 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.002 0.997 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.002 0.997 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.002 0.997 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.002 0.997 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.002 0.997 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.002 0.997 0.000
H93.8 Other specified disorders of ear
0.002 0.997 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.002 0.997 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.002 0.997 0.000
H91.0 Ototoxic hearing loss
0.002 0.997 0.000
I30.9 Acute pericarditis, unspecified
0.003 0.997 0.000
D26 Other benign neoplasms of uterus
0.002 0.997 0.000
H57.8 Other specified disorders of eye and adnexa
0.002 0.998 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.002 0.998 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.002 0.998 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.002 0.998 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.002 0.998 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.002 0.998 0.000
D83 Common variable immunodeficiency
0.002 0.998 0.000
H93 Other disorders of ear, not elsewhere classified
0.002 0.998 0.000
T17 Foreign body in respiratory tract
0.000 0.998 0.002
M48.92 Spondylopathy, unspecified (Cervical region)
0.002 0.998 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.000 0.998 0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
I67.1 Cerebral aneurysm, nonruptured
0.000 0.998 0.002
T17.9 Foreign body in respiratory tract, part unspecified
0.000 0.998 0.002
H94.8 Other specified disorders of ear in diseases classified elsewhere
0.002 0.998 0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere
0.002 0.998 0.000
D84.8 Other specified immunodeficiencies
0.002 0.998 0.000
S41.1 Open wound of upper arm
0.000 0.998 0.002
D82 Immunodeficiency associated with other major defects
0.002 0.998 0.000
G24 Dystonia
0.002 0.998 0.000
S12.20 Fracture of other specified cervical vertebra (closed)
0.002 0.998 0.000
H91.2 Sudden idiopathic hearing loss
0.002 0.998 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.998 0.002
D81 Combined immunodeficiencies
0.002 0.998 0.000
M16.9 Coxarthrosis, unspecified
0.000 0.998 0.002
G24.5 Blepharospasm
0.002 0.998 0.000
G50 Disorders of trigeminal nerve
0.002 0.998 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.002 0.998 0.000
G24.1 Idiopathic familial dystonia
0.002 0.998 0.000
G24.0 Drug-induced dystonia
0.002 0.998 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.002 0.998 0.000
C91.0 Acute lymphoblastic leukaemia
0.002 0.998 0.000
D83.9 Common variable immunodeficiency, unspecified
0.002 0.998 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.000 0.998 0.002
T17.8 Foreign body in other and multiple parts of respiratory tract
0.000 0.998 0.002
G50.1 Atypical facial pain
0.002 0.998 0.000
T75.4 Effects of electric current
0.002 0.998 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.002 0.998 0.000
D26.7 Other parts of uterus
0.002 0.998 0.000
T16 Foreign body in ear
0.000 0.998 0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.002 0.998 0.000
G31.2 Degeneration of nervous system due to alcohol
0.002 0.998 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.002 0.998 0.000
R06.8 Other and unspecified abnormalities of breathing
0.002 0.998 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.002 0.998 0.000
T17.4 Foreign body in trachea
0.000 0.998 0.002
T17.1 Foreign body in nostril
0.000 0.998 0.002
T17.0 Foreign body in nasal sinus
0.000 0.998 0.002
T50.9 Other and unspecified drugs, medicaments and biological substances
0.001 0.998 0.001
D83.8 Other common variable immunodeficiencies
0.002 0.998 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.002 0.998 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.002 0.998 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.002 0.998 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.002 0.998 0.000
G50.8 Other disorders of trigeminal nerve
0.002 0.998 0.000
H93.9 Disorder of ear, unspecified
0.002 0.998 0.000
H93.0 Degenerative and vascular disorders of ear
0.002 0.998 0.000
T17.3 Foreign body in larynx
0.000 0.998 0.002
F20.0 Paranoid schizophrenia
0.000 0.998 0.002
M81.4 Drug-induced osteoporosis
0.002 0.998 0.000
O42.9 Premature rupture of membranes, unspecified
0.000 0.998 0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.998 0.002
H57.9 Disorder of eye and adnexa, unspecified
0.002 0.998 0.000
T78.2 Anaphylactic shock, unspecified
0.002 0.998 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.998 0.002
C90.2 Plasmacytoma, extramedullary
0.000 0.998 0.002
D82.9 Immunodeficiency associated with major defect, unspecified
0.002 0.998 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.002 0.998 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.002 0.998 0.000
D82.2 Immunodeficiency with short-limbed stature
0.002 0.998 0.000
D82.0 Wiskott-Aldrich syndrome
0.002 0.998 0.000
G24.4 Idiopathic orofacial dystonia
0.002 0.998 0.000
G24.2 Idiopathic nonfamilial dystonia
0.002 0.998 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.002 0.998 0.000
G24.9 Dystonia, unspecified
0.002 0.998 0.000
R39.1 Other difficulties with micturition
0.000 0.998 0.002
T19.2 Foreign body in vulva and vagina
0.000 0.998 0.002
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.002 0.998 0.000
D81.9 Combined immunodeficiency, unspecified
0.002 0.998 0.000
D81.8 Other combined immunodeficiencies
0.002 0.998 0.000
D81.7 Major histocompatibility complex class II deficiency
0.002 0.998 0.000
D81.6 Major histocompatibility complex class I deficiency
0.002 0.998 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.002 0.998 0.000
D81.4 Nezelof's syndrome
0.002 0.998 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.002 0.998 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.002 0.998 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.002 0.998 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.002 0.998 0.000
D82.1 Di George's syndrome
0.002 0.998 0.000
G24.3 Spasmodic torticollis
0.002 0.998 0.000
N21 Calculus of lower urinary tract
0.000 0.998 0.002
T19 Foreign body in genito-urinary tract
0.000 0.998 0.002
S22.00 Fracture of thoracic vertebra (closed)
0.002 0.998 0.000
D26.9 Uterus, unspecified
0.002 0.998 0.000
D86.9 Sarcoidosis, unspecified
0.002 0.998 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.002 0.998 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.998 0.002
H93.2 Other abnormal auditory perceptions
0.002 0.998 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.002 0.998 0.000
G31.0 Circumscribed brain atrophy
0.002 0.998 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.001 0.998 0.000
I30.1 Infective pericarditis
0.002 0.998 0.000
Z34.8 Supervision of other normal pregnancy
0.000 0.998 0.002
C90.3 Solitary plasmacytoma
0.000 0.998 0.002
H93.3 Disorders of acoustic nerve
0.002 0.998 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.000 0.998 0.002
M81.49 Drug-induced osteoporosis (Site unspecified)
0.002 0.998 0.000
Q78.0 Osteogenesis imperfecta
0.000 0.998 0.002
T75 Effects of other external causes
0.002 0.998 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.998 0.002
E88.2 Lipomatosis, not elsewhere classified
0.000 0.998 0.002
M54.64 Pain in thoracic spine (Thoracic region)
0.002 0.998 0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec
0.002 0.998 0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other
0.002 0.998 0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot
0.002 0.998 0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh
0.002 0.998 0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand
0.002 0.998 0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm
0.002 0.998 0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm
0.002 0.998 0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region
0.002 0.998 0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites
0.002 0.998 0.000
T19.1 Foreign body in bladder
0.000 0.998 0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.002 0.998 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.002 0.998 0.000
I30 Acute pericarditis
0.002 0.998 0.000
M81.48 Drug-induced osteoporosis (Other)
0.002 0.998 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.002 0.998 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.002 0.998 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.002 0.998 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.002 0.998 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.002 0.998 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.002 0.998 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.002 0.998 0.000
I30.8 Other forms of acute pericarditis
0.002 0.998 0.000
N21.8 Other lower urinary tract calculus
0.000 0.998 0.002
T75.1 Drowning and nonfatal submersion
0.002 0.998 0.000
T78 Adverse effects, not elsewhere classified
0.002 0.998 0.000
M48.06 Spinal stenosis (Lumbar region)
0.002 0.998 0.000
M41.9 Scoliosis, unspecified
0.000 0.998 0.002
C56 Malignant neoplasm of ovary
0.000 0.998 0.002
T15 Foreign body on external eye
0.000 0.998 0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.000 0.998 0.002
T80.2 Infections following infusion, transfusion and therapeutic injection
0.000 0.998 0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.000 0.998 0.002
T19.9 Foreign body in genito-urinary tract, part unspecified
0.000 0.998 0.001
T19.8 Foreign body in other and multiple parts of genito-urinary tract
0.000 0.998 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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