TreeWAS – Variant ID: rs7735249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M75.0 Adhesive capsulitis of shoulder	0.000	0.964	0.036
N28.1 Cyst of kidney, acquired	0.036	0.964	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.029	0.971	0.000
N28.8 Other specified disorders of kidney and ureter	0.025	0.975	0.000
N28.0 Ischaemia and infarction of kidney	0.024	0.976	0.000
H25.0 Senile incipient cataract	0.000	0.978	0.022
N25-N29 Other disorders of kidney and ureter	0.021	0.979	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.019	0.981	0.000
N26 Unspecified contracted kidney	0.019	0.981	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.018	0.982	0.000
N25 Disorders resulting from impaired renal tubular function	0.017	0.983	0.000
Z90.2 Acquired absence of lung [part of]	0.017	0.983	0.000
M51.2 Other specified intervertebral disk displacement	0.017	0.983	0.000
N27 Small kidney of unknown cause	0.016	0.984	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.015	0.985	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.985	0.015
S82.8 Fractures of other parts of lower leg	0.014	0.986	0.000
N25.1 Nephrogenic diabetes insipidus	0.014	0.986	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
N29.0 Late syphilis of kidney	0.013	0.987	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.012	0.987	0.000
N25.0 Renal osteodystrophy	0.012	0.987	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.012	0.988	0.000
N27.0 Small kidney, unilateral	0.012	0.988	0.000
N27.9 Small kidney, unspecified	0.011	0.988	0.000
N27.1 Small kidney, bilateral	0.011	0.988	0.000
S82.81 Fractures of other parts of lower leg (open)	0.012	0.988	0.000
E78.0 Pure hypercholesterolaemia	0.011	0.989	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
S82.86 Maisonneuve's fracture	0.010	0.989	0.000
M51 Other intervertebral disk disorders	0.010	0.990	0.000
S82.10 Fracture of upper end of tibia (closed)	0.010	0.990	0.000
S82 Fracture of lower leg, including ankle	0.010	0.990	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.010	0.990	0.000
S82.1 Fracture of upper end of tibia	0.010	0.990	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
S82.4 Fracture of fibula alone	0.008	0.991	0.000
M51.9 Intervertebral disk disorder, unspecified	0.008	0.992	0.000
M51.4 Schmorl's nodes	0.008	0.992	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.992	0.008
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
M51.8 Other specified intervertebral disk disorders	0.008	0.992	0.000
S82.40 Fracture of fibula alone (closed)	0.008	0.992	0.000
M51.3 Other specified intervertebral disk degeneration	0.007	0.992	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.007	0.992	0.000
S82.7 Multiple fractures of lower leg	0.007	0.993	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.007	0.993	0.000
S82.9 Fracture of lower leg, part unspecified	0.007	0.993	0.000
S82.0 Fracture of patella	0.007	0.993	0.000
S82.6 Fracture of lateral malleolus	0.007	0.993	0.000
S82.11 Fracture of upper end of tibia (open)	0.007	0.993	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
S82.5 Fracture of medial malleolus	0.007	0.993	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
C50.5 Lower-outer quadrant of breast	0.007	0.993	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
S82.61 Fracture of lateral malleolus (open)	0.006	0.994	0.000
S82.41 Fracture of fibula alone (open)	0.006	0.994	0.000
S82.3 Fracture of lower end of tibia	0.006	0.994	0.000
S82.01 Fracture of patella (open)	0.006	0.994	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.994	0.006
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.006	0.994	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.994	0.006
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.005	0.994	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.005	0.994	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.005	0.994	0.000
S82.70 Multiple fractures of lower leg (closed)	0.005	0.994	0.000
S82.71 Multiple fractures of lower leg (open)	0.005	0.994	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.005	0.994	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.005	0.994	0.000
S82.51 Fracture of medial malleolus (open)	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
S82.2 Fracture of shaft of tibia	0.004	0.996	0.001
C50.2 Upper-inner quadrant of breast	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
S82.31 Fracture of lower end of tibia (open)	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.996	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.004	0.996	0.000
Z35.5 Supervision of elderly primigravida	0.004	0.996	0.000
C50 Malignant neoplasm of breast	0.004	0.996	0.000
D61 Other aplastic anaemias	0.000	0.996	0.004
R87.6 Abnormal cytological findings	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.000	0.997	0.003
C50.6 Axillary tail of breast	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
D58.0 Hereditary spherocytosis	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
S83.2 Tear of meniscus, current	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.003	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.997	0.001
Y46.5 Valproic acid	0.003	0.997	0.000
D61.8 Other specified aplastic anaemias	0.000	0.997	0.003
D61.3 Idiopathic aplastic anaemia	0.000	0.997	0.003
D61.2 Aplastic anaemia due to other external agents	0.000	0.997	0.003
D61.1 Drug-induced aplastic anaemia	0.000	0.997	0.003
D61.0 Constitutional aplastic anaemia	0.000	0.997	0.003
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
D58 Other hereditary haemolytic anaemias	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
G50.0 Trigeminal neuralgia	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.997	0.003
Y40 Systemic antibiotics	0.003	0.997	0.000
C50.1 Central portion of breast	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
E78.8 Other disorders of lipoprotein metabolism	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.000	0.997	0.003
K29.1 Other acute gastritis	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
E78.4 Other hyperlipidaemia	0.003	0.997	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.003	0.997	0.000
Z35 Supervision of high-risk pregnancy	0.003	0.997	0.000
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.002	0.997	0.000
S87 Crushing injury of lower leg	0.002	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.997	0.000
S84 Injury of nerves at lower leg level	0.002	0.997	0.000
E78.1 Pure hyperglyceridaemia	0.002	0.997	0.000
S83.7 Injury to multiple structures of knee	0.002	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.997	0.000
S83.1 Dislocation of knee	0.002	0.997	0.000
S83.0 Dislocation of patella	0.002	0.997	0.000
Y46.2 Hydantoin derivatives	0.002	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
C50.8 Overlapping lesion of breast	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.002	0.997	0.000
H18.2 Other corneal oedema	0.002	0.997	0.000
R87 Abnormal findings in specimens from female genital organs	0.002	0.997	0.000
C50.0 Nipple and areola	0.002	0.997	0.000
E78.6 Lipoprotein deficiency	0.002	0.997	0.000
E78.3 Hyperchylomicronaemia	0.002	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
R87.7 Abnormal histological findings	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.000	0.998	0.002
D60.1 Transient acquired pure red cell aplasia	0.000	0.998	0.002
D60.0 Chronic acquired pure red cell aplasia	0.000	0.998	0.002
W06.0 Home	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.002	0.998	0.000
Z35.6 Supervision of very young primigravida	0.002	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
J37.0 Chronic laryngitis	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
R87.8 Other abnormal findings	0.002	0.998	0.000
R87.5 Abnormal microbiological findings	0.002	0.998	0.000
R87.4 Abnormal immunological findings	0.002	0.998	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R87.1 Abnormal level of hormones	0.002	0.998	0.000
R87.0 Abnormal level of enzymes	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
C50.4 Upper-outer quadrant of breast	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
H25 Senile cataract	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
G35 Multiple sclerosis	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
S89 Other and unspecified injuries of lower leg	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.001	0.998	0.001
H16.0 Corneal ulcer	0.002	0.998	0.000
R87.9 Unspecified abnormal finding	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
C25.0 Head of pancreas	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
C25.2 Tail of pancreas	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.998	0.002
W19.9 Unspecified place	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.998	0.000
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
K14.0 Glossitis	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
H53.8 Other visual disturbances	0.000	0.998	0.002
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.001	0.998	0.000
S89.1 Other specified injuries of lower leg	0.001	0.998	0.000
S89.0 Multiple injuries of lower leg	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
J86 Pyothorax	0.000	0.998	0.002
C67.7 Urachus	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Y48.3 Local anaesthetics	0.001	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.998	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
K31.7 Polyp of stomach and duodenum	0.002	0.998	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.998	0.000
C25.1 Body of pancreas	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations