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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7762933
log Bayes Factor = 61.2734
Chromosome 6   position 31,162,520  (GRCh37) Explore rs7762933 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.002 0.998
D86 Sarcoidosis
0.000 0.003 0.997
R31 Unspecified haematuria
0.997 0.003 0.000
D64 Other anaemias
0.000 0.004 0.996
D64.9 Anaemia, unspecified
0.000 0.005 0.995
D86.9 Sarcoidosis, unspecified
0.000 0.007 0.993
L40 Psoriasis
0.000 0.011 0.989
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.027 0.973
L40.5 Arthropathic psoriasis
0.000 0.030 0.970
D69 Purpura and other haemorrhagic conditions
0.000 0.035 0.965
D50-D53 Nutritional anaemias
0.000 0.036 0.964
D69.6 Thrombocytopenia, unspecified
0.000 0.041 0.959
D86.3 Sarcoidosis of skin
0.000 0.072 0.928
D80 Immunodeficiency with predominantly antibody defects
0.000 0.097 0.903
L40.0 Psoriasis vulgaris
0.000 0.097 0.903
D50 Iron deficiency anaemia
0.000 0.108 0.892
D50.9 Iron deficiency anaemia, unspecified
0.000 0.118 0.882
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.128 0.872
D66 Hereditary factor VIII deficiency
0.000 0.142 0.858
E03 Other hypothyroidism
0.000 0.143 0.857
D51 Vitamin B12 deficiency anaemia
0.000 0.149 0.851
D62 Acute posthaemorrhagic anaemia
0.000 0.150 0.850
D61 Other aplastic anaemias
0.000 0.156 0.844
D70 Agranulocytosis
0.000 0.167 0.833
D69.2 Other nonthrombocytopenic purpura
0.000 0.172 0.828
D64.8 Other specified anaemias
0.000 0.178 0.822
D55-D59 Haemolytic anaemias
0.000 0.178 0.822
D69.5 Secondary thrombocytopenia
0.000 0.189 0.811
D69.4 Other primary thrombocytopenia
0.000 0.190 0.810
L40.1 Generalised pustular psoriasis
0.000 0.194 0.806
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.196 0.804
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.196 0.803
D52 Folate deficiency anaemia
0.000 0.204 0.796
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.207 0.793
D84 Other immunodeficiencies
0.000 0.214 0.786
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.235 0.765
D86.0 Sarcoidosis of lung
0.000 0.236 0.764
D72 Other disorders of white blood cells
0.000 0.244 0.756
D61.9 Aplastic anaemia, unspecified
0.000 0.255 0.745
L40.8 Other psoriasis
0.000 0.261 0.739
L40.3 Pustulosis palmaris et plantaris
0.000 0.263 0.737
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.265 0.734
D83 Common variable immunodeficiency
0.000 0.266 0.734
E00-E07 Disorders of thyroid gland
0.000 0.278 0.722
L40.4 Guttate psoriasis
0.000 0.279 0.721
D81 Combined immunodeficiencies
0.000 0.284 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.285 0.714
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.285 0.714
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.285 0.714
D64.0 Hereditary sideroblastic anaemia
0.000 0.285 0.714
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.287 0.713
D64.3 Other sideroblastic anaemias
0.000 0.291 0.709
L40.2 Acrodermatitis continua
0.000 0.291 0.709
D86.1 Sarcoidosis of lymph nodes
0.000 0.296 0.704
E05.9 Thyrotoxicosis, unspecified
0.000 0.298 0.702
D69.8 Other specified haemorrhagic conditions
0.000 0.308 0.692
D59 Acquired haemolytic anaemia
0.000 0.309 0.690
D58 Other hereditary haemolytic anaemias
0.000 0.320 0.680
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.324 0.676
D52.9 Folate deficiency anaemia, unspecified
0.000 0.325 0.675
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.326 0.674
E03.8 Other specified hypothyroidism
0.000 0.332 0.668
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.348 0.651
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.353 0.647
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.353 0.647
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.353 0.647
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.353 0.647
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.353 0.647
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.353 0.647
D67 Hereditary factor IX deficiency
0.000 0.353 0.647
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.353 0.647
D84.9 Immunodeficiency, unspecified
0.000 0.360 0.640
D50.1 Sideropenic dysphagia
0.000 0.361 0.639
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.364 0.636
D69.1 Qualitative platelet defects
0.000 0.364 0.636
D82 Immunodeficiency associated with other major defects
0.000 0.371 0.629
D84.1 Defects in the complement system
0.000 0.372 0.628
D61.0 Constitutional aplastic anaemia
0.000 0.374 0.626
D74 Methaemoglobinaemia
0.000 0.375 0.625
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.375 0.625
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.375 0.625
D72.8 Other specified disorders of white blood cells
0.000 0.377 0.623
D72.1 Eosinophilia
0.000 0.377 0.623
D58.0 Hereditary spherocytosis
0.000 0.379 0.621
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.380 0.620
E03.5 Myxoedema coma
0.000 0.385 0.615
E03.4 Atrophy of thyroid (acquired)
0.000 0.385 0.615
E03.3 Postinfectious hypothyroidism
0.000 0.385 0.615
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.388 0.611
D51.2 Transcobalamin II deficiency
0.000 0.390 0.610
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.390 0.610
D61.8 Other specified aplastic anaemias
0.000 0.395 0.605
D61.3 Idiopathic aplastic anaemia
0.000 0.395 0.605
D61.2 Aplastic anaemia due to other external agents
0.000 0.395 0.605
E03.1 Congenital hypothyroidism without goitre
0.000 0.396 0.604
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.401 0.599
D59.1 Other autoimmune haemolytic anaemias
0.000 0.406 0.594
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.407 0.593
D57 Sickle-cell disorders
0.000 0.410 0.589
D55 Anaemia due to enzyme disorders
0.000 0.410 0.589
D53 Other nutritional anaemias
0.000 0.411 0.589
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.412 0.588
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.414 0.586
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.423 0.577
D52.8 Other folate deficiency anaemias
0.000 0.429 0.570
D52.1 Drug-induced folate deficiency anaemia
0.000 0.429 0.570
D52.0 Dietary folate deficiency anaemia
0.000 0.429 0.570
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.430 0.569
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.431 0.569
D89.3 Immune reconstitution syndrome
0.000 0.431 0.569
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.436 0.564
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.443 0.557
D61.1 Drug-induced aplastic anaemia
0.000 0.445 0.555
D86.8 Sarcoidosis of other and combined sites
0.000 0.449 0.551
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.456 0.544
D83.9 Common variable immunodeficiency, unspecified
0.000 0.456 0.543
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.458 0.542
D72.9 Disorder of white blood cells, unspecified
0.000 0.458 0.542
D72.0 Genetic anomalies of leukocytes
0.000 0.458 0.542
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.466 0.534
D76.3 Other histiocytosis syndromes
0.000 0.467 0.533
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.469 0.531
D83.8 Other common variable immunodeficiencies
0.000 0.474 0.526
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.474 0.526
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.474 0.526
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.474 0.526
D69.0 Allergic purpura
0.000 0.478 0.522
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.482 0.517
E00 Congenital iodine-deficiency syndrome
0.000 0.482 0.517
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.514
D81.8 Other combined immunodeficiencies
0.000 0.486 0.514
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.514
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.514
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.514
D81.4 Nezelof's syndrome
0.000 0.486 0.514
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.514
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.514
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.514
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.514
E05.5 Thyroid crisis or storm
0.000 0.489 0.511
E05.4 Thyrotoxicosis factitia
0.000 0.489 0.511
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.489 0.511
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.489 0.511
D59.8 Other acquired haemolytic anaemias
0.000 0.505 0.495
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.505 0.495
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.505 0.495
D59.3 Haemolytic-uraemic syndrome
0.000 0.505 0.495
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.505 0.495
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.505 0.495
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.512 0.488
D58.1 Hereditary elliptocytosis
0.000 0.512 0.488
D60.8 Other acquired pure red cell aplasias
0.000 0.515 0.485
D60.1 Transient acquired pure red cell aplasia
0.000 0.515 0.485
D60.0 Chronic acquired pure red cell aplasia
0.000 0.515 0.485
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.516 0.483
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.516 0.483
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.516 0.483
D89.1 Cryoglobulinaemia
0.000 0.525 0.474
D69.9 Haemorrhagic condition, unspecified
0.000 0.526 0.474
K75 Other inflammatory liver diseases
0.000 0.538 0.462
D84.8 Other specified immunodeficiencies
0.000 0.538 0.462
D58.2 Other haemoglobinopathies
0.000 0.541 0.459
K70-K77 Diseases of liver
0.000 0.542 0.458
D56 Thalassaemia
0.000 0.545 0.455
K75.4 Autoimmune hepatitis
0.000 0.545 0.455
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.549 0.451
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.549 0.451
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.549 0.451
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.549 0.451
D82.2 Immunodeficiency with short-limbed stature
0.000 0.549 0.451
D82.0 Wiskott-Aldrich syndrome
0.000 0.549 0.451
K73 Chronic hepatitis, not elsewhere classified
0.000 0.549 0.451
K90 Intestinal malabsorption
0.000 0.549 0.451
K70 Alcoholic liver disease
0.000 0.549 0.451
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.550 0.450
K75.8 Other specified inflammatory liver diseases
0.000 0.550 0.450
D74.9 Methaemoglobinaemia, unspecified
0.000 0.552 0.448
D74.8 Other methaemoglobinaemias
0.000 0.552 0.448
D74.0 Congenital methaemoglobinaemia
0.000 0.552 0.448
E07 Other disorders of thyroid
0.000 0.553 0.447
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.554 0.445
D50.8 Other iron deficiency anaemias
0.000 0.559 0.441
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.569 0.431
E04 Other non-toxic goitre
0.000 0.576 0.424
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.577 0.423
D55.8 Other anaemias due to enzyme disorders
0.000 0.577 0.423
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.577 0.423
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.577 0.423
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.577 0.423
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.577 0.423
D57.8 Other sickle-cell disorders
0.000 0.577 0.423
D57.3 Sickle-cell trait
0.000 0.577 0.423
D57.2 Double heterozygous sickling disorders
0.000 0.577 0.423
D57.1 Sickle-cell anaemia without crisis
0.000 0.577 0.423
D57.0 Sickle-cell anaemia with crisis
0.000 0.577 0.423
D53.8 Other specified nutritional anaemias
0.000 0.577 0.422
D53.2 Scorbutic anaemia
0.000 0.577 0.422
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.577 0.422
D53.0 Protein deficiency anaemia
0.000 0.577 0.422
K70.9 Alcoholic liver disease, unspecified
0.000 0.578 0.422
K73.9 Chronic hepatitis, unspecified
0.000 0.588 0.412
K70.1 Alcoholic hepatitis
0.000 0.592 0.408
K70.0 Alcoholic fatty liver
0.000 0.602 0.398
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.609 0.390
E04.0 Non-toxic diffuse goitre
0.000 0.614 0.386
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.621 0.379
E07.8 Other specified disorders of thyroid
0.000 0.623 0.377
K72 Hepatic failure, not elsewhere classified
0.000 0.623 0.377
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.629 0.371
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.629 0.371
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.629 0.371
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.629 0.371
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.629 0.371
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.629 0.371
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.629 0.371
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.629 0.371
E06 Thyroiditis
0.000 0.635 0.364
D82.1 Di George's syndrome
0.001 0.636 0.364
K75.0 Abscess of liver
0.000 0.636 0.364
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.646 0.354
K90.9 Intestinal malabsorption, unspecified
0.000 0.655 0.345
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.656 0.344
E05.8 Other thyrotoxicosis
0.001 0.659 0.341
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.666 0.334
K75.2 Nonspecific reactive hepatitis
0.000 0.668 0.331
K75.1 Phlebitis of portal vein
0.000 0.668 0.331
K74 Fibrosis and cirrhosis of liver
0.000 0.669 0.331
K77 Liver disorders in diseases classified elsewhere
0.000 0.671 0.328
D56.9 Thalassaemia, unspecified
0.000 0.673 0.326
D56.8 Other thalassaemias
0.000 0.673 0.326
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.673 0.326
D56.2 Delta-beta thalassaemia
0.000 0.673 0.326
D56.0 Alpha thalassaemia
0.000 0.673 0.326
K74.0 Hepatic fibrosis
0.000 0.676 0.324
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.676 0.324
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.676 0.324
K90.3 Pancreatic steatorrhoea
0.000 0.676 0.323
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.676 0.323
K90.1 Tropical sprue
0.000 0.676 0.323
E07.1 Dyshormogenetic goitre
0.000 0.679 0.320
E07.0 Hypersecretion of calcitonin
0.000 0.679 0.320
D53.9 Nutritional anaemia, unspecified
0.000 0.680 0.320
K72.0 Acute and subacute hepatic failure
0.000 0.681 0.318
E04.8 Other specified non-toxic goitre
0.000 0.696 0.304
E06.3 Autoimmune thyroiditis
0.000 0.705 0.295
K72.9 Hepatic failure, unspecified
0.000 0.713 0.287
D56.1 Beta thalassaemia
0.001 0.714 0.286
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.715 0.284
K71 Toxic liver disease
0.000 0.727 0.273
D75 Other diseases of blood and blood-forming organs
0.000 0.729 0.271
K70.4 Alcoholic hepatic failure
0.000 0.731 0.269
E04.2 Non-toxic multinodular goitre
0.000 0.733 0.267
E06.4 Drug-induced thyroiditis
0.000 0.738 0.261
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.738 0.261
E06.0 Acute thyroiditis
0.000 0.738 0.261
E06.5 Other chronic thyroiditis
0.000 0.745 0.254
D56.3 Thalassaemia trait
0.001 0.746 0.254
K72.1 Chronic hepatic failure
0.000 0.749 0.250
K90.8 Other intestinal malabsorption
0.000 0.750 0.249
D73 Diseases of spleen
0.000 0.760 0.240
K74.4 Secondary biliary cirrhosis
0.000 0.763 0.237
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.763 0.237
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.764 0.236
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.764 0.236
D75.0 Familial erythrocytosis
0.000 0.778 0.222
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.779 0.221
K74.1 Hepatic sclerosis
0.000 0.788 0.212
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.796 0.204
L40-L45 Papulosquamous disorders
0.001 0.796 0.204
K70.3 Alcoholic cirrhosis of liver
0.000 0.798 0.202
K71.9 Toxic liver disease, unspecified
0.000 0.804 0.196
K71.8 Toxic liver disease with other disorders of liver
0.000 0.804 0.196
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.804 0.196
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.804 0.196
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.804 0.196
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.804 0.196
K71.2 Toxic liver disease with acute hepatitis
0.000 0.804 0.196
K71.0 Toxic liver disease with cholestasis
0.000 0.804 0.196
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.804 0.196
E04.1 Non-toxic single thyroid nodule
0.000 0.808 0.192
E06.9 Thyroiditis, unspecified
0.001 0.809 0.190
G35 Multiple sclerosis
0.000 0.811 0.189
D73.1 Hypersplenism
0.000 0.817 0.183
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.826 0.174
D73.2 Chronic congestive splenomegaly
0.000 0.828 0.172
D73.9 Disease of spleen, unspecified
0.000 0.828 0.171
D73.3 Abscess of spleen
0.000 0.829 0.170
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.829 0.170
D73.5 Infarction of spleen
0.000 0.831 0.169
K74.6 Other and unspecified cirrhosis of liver
0.000 0.831 0.169
E04.9 Non-toxic goitre, unspecified
0.000 0.842 0.158
E06.1 Subacute thyroiditis
0.001 0.845 0.154
K74.5 Biliary cirrhosis, unspecified
0.000 0.848 0.152
L44 Other papulosquamous disorders
0.001 0.853 0.146
L41 Parapsoriasis
0.001 0.853 0.146
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.853 0.146
D73.4 Cyst of spleen
0.001 0.856 0.144
D75.2 Essential thrombocytosis
0.000 0.875 0.125
M06.9 Rheumatoid arthritis, unspecified
0.123 0.877 0.000
D73.8 Other diseases of spleen
0.001 0.881 0.119
M06 Other rheumatoid arthritis
0.117 0.883 0.000
K75.9 Inflammatory liver disease, unspecified
0.001 0.883 0.116
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.115 0.885 0.000
L42 Pityriasis rosea
0.001 0.889 0.111
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.111 0.889 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.894 0.106
M06.3 Rheumatoid nodule
0.106 0.894 0.000
L41.9 Parapsoriasis, unspecified
0.001 0.895 0.105
L41.8 Other parapsoriasis
0.001 0.895 0.105
L41.5 Retiform parapsoriasis
0.001 0.895 0.105
L41.4 Large plaque parapsoriasis
0.001 0.895 0.105
L41.3 Small plaque parapsoriasis
0.001 0.895 0.105
L41.2 Lymphomatoid papulosis
0.001 0.895 0.105
L41.1 Pityriasis lichenoides chronica
0.001 0.895 0.105
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.895 0.105
L44.9 Papulosquamous disorder, unspecified
0.001 0.895 0.105
L44.8 Other specified papulosquamous disorders
0.001 0.895 0.105
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.895 0.105
L44.3 Lichen ruber moniliformis
0.001 0.895 0.105
L44.2 Lichen striatus
0.001 0.895 0.105
L44.1 Lichen nitidus
0.001 0.895 0.105
L44.0 Pityriasis rubra pilaris
0.001 0.895 0.105
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.105 0.895 0.000
M06.0 Seronegative rheumatoid arthritis
0.105 0.895 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.103 0.897 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.899 0.101
M06.34 Rheumatoid nodule (Hand)
0.101 0.899 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.100 0.900 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.099 0.901 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.097 0.903 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.903 0.097
K90-K93 Other diseases of the digestive system
0.000 0.907 0.093
D68 Other coagulation defects
0.000 0.907 0.093
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.091 0.909 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.090 0.910 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.910 0.089
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.090 0.910 0.000
M06.8 Other specified rheumatoid arthritis
0.087 0.913 0.000
M06.4 Inflammatory polyarthropathy
0.086 0.914 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.085 0.915 0.000
K74.3 Primary biliary cirrhosis
0.000 0.915 0.084
M06.2 Rheumatoid bursitis
0.084 0.916 0.000
M06.1 Adult-onset Still's disease
0.084 0.916 0.000
M05 Seropositive rheumatoid arthritis
0.082 0.918 0.000
M05-M14 Inflammatory polyarthropathies
0.081 0.919 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.081 0.919 0.000
G62.9 Polyneuropathy, unspecified
0.000 0.920 0.080
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.079 0.921 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.078 0.922 0.000
M06.33 Rheumatoid nodule (Forearm)
0.077 0.922 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.077 0.923 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.076 0.924 0.000
M06.38 Rheumatoid nodule (Other)
0.076 0.924 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.076 0.924 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.076 0.924 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.076 0.924 0.000
G62 Other polyneuropathies
0.000 0.924 0.076
Chapter VI Diseases of the nervous system
0.000 0.924 0.076
M06.08 Seronegative rheumatoid arthritis (Other)
0.075 0.925 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.075 0.925 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.075 0.925 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.075 0.925 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.075 0.925 0.000
D68.6 Other Thrombophilia
0.000 0.925 0.075
D75.8 Other specified diseases of blood and blood-forming organs
0.001 0.927 0.073
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.927 0.073
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.072 0.928 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.929 0.071
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.071 0.929 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.071 0.929 0.000
Chapter XI Diseases of the digestive system
0.000 0.930 0.070
G30-G32 Other degenerative diseases of the nervous system
0.000 0.930 0.070
E27 Other disorders of adrenal gland
0.000 0.930 0.070
G36 Other acute disseminated demyelination
0.000 0.931 0.069
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.931 0.069
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.069 0.931 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.932 0.068
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.068 0.932 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.068 0.932 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.933 0.067
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.067 0.933 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.067 0.933 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.933 0.067
G70-G73 Diseases of myoneural junction and muscle
0.000 0.933 0.067
G62.1 Alcoholic polyneuropathy
0.000 0.933 0.067
M14 Arthropathies in other diseases classified elsewhere
0.066 0.934 0.000
K76 Other diseases of liver
0.000 0.934 0.066
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.065 0.934 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.065 0.935 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.935 0.065
D68.1 Hereditary factor XI deficiency
0.000 0.935 0.064
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.064 0.936 0.000
M05.1 Rheumatoid lung disease
0.064 0.936 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.936 0.064
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.063 0.937 0.000
D75.1 Secondary polycythaemia
0.000 0.937 0.062
M06.88 Other specified rheumatoid arthritis (Other)
0.063 0.937 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.063 0.937 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.063 0.937 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.063 0.937 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.063 0.937 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.063 0.937 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.063 0.937 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.063 0.937 0.000
# Top node
0.000 0.937 0.063
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.062 0.937 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.937 0.063
M06.48 Inflammatory polyarthropathy (Other)
0.062 0.938 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.062 0.938 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.062 0.938 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.062 0.938 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.062 0.938 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.062 0.938 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.062 0.938 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.062 0.938 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.061 0.939 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.061 0.939 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.061 0.939 0.000
M06.18 Adult-onset Still's disease (Other)
0.061 0.939 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.061 0.939 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.061 0.939 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.061 0.939 0.000
M06.14 Adult-onset Still's disease (Hand)
0.061 0.939 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.061 0.939 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.061 0.939 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.061 0.939 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.061 0.939 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.061 0.939 0.000
M06.28 Rheumatoid bursitis (Other)
0.061 0.939 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.061 0.939 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.061 0.939 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.061 0.939 0.000
M06.24 Rheumatoid bursitis (Hand)
0.061 0.939 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.061 0.939 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.061 0.939 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.061 0.939 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.061 0.939 0.000
E27.2 Addisonian crisis
0.000 0.940 0.060
L50-L54 Urticaria and erythema
0.000 0.940 0.060
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.940 0.060
M08 Juvenile arthritis
0.060 0.940 0.000
D68.5 Primary Thrombophilia
0.000 0.940 0.060
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.059 0.941 0.000
M05.0 Felty's syndrome
0.059 0.941 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.059 0.941 0.000
M05.2 Rheumatoid vasculitis
0.059 0.941 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.058 0.941 0.000
G70 Myasthenia gravis and other myoneural disorders
0.000 0.942 0.058
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.058 0.942 0.000
G83 Other paralytic syndromes
0.000 0.942 0.058
G81 Hemiplegia
0.000 0.942 0.058
L10-L14 Bullous disorders
0.000 0.942 0.058
G31.8 Other specified degenerative diseases of nervous system
0.000 0.943 0.057
G31.0 Circumscribed brain atrophy
0.000 0.943 0.057
G62.0 Drug-induced polyneuropathy
0.000 0.943 0.056
M11 Other crystal arthropathies
0.056 0.944 0.000
L43 Lichen planus
0.001 0.944 0.055
D68.4 Acquired coagulation factor deficiency
0.000 0.944 0.056
M14.6 Neuropathic arthropathy
0.056 0.944 0.000
L50 Urticaria
0.000 0.944 0.056
G83.4 Cauda equina syndrome
0.000 0.944 0.056
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.945 0.055
K76.1 Chronic passive congestion of liver
0.000 0.945 0.055
G62.2 Polyneuropathy due to other toxic agents
0.000 0.945 0.055
G60 Hereditary and idiopathic neuropathy
0.000 0.945 0.055
M12 Other specific arthropathies
0.054 0.946 0.000
D63.0 Anaemia in neoplastic disease
0.000 0.946 0.054
M05.8 Other seropositive rheumatoid arthritis
0.054 0.946 0.000
G71 Primary disorders of muscles
0.000 0.946 0.053
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.053 0.947 0.000
G64 Other disorders of peripheral nervous system
0.000 0.948 0.052
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.948 0.052
E24 Cushing's syndrome
0.000 0.948 0.052
G70.0 Myasthenia gravis
0.000 0.948 0.052
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.949 0.051
E20 Hypoparathyroidism
0.000 0.949 0.051
M05.19 Rheumatoid lung disease (Site unspecified)
0.051 0.949 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.949 0.051
D68.0 Von Willebrand's disease
0.000 0.949 0.050
G81.9 Hemiplegia, unspecified
0.000 0.949 0.051
G00 Bacterial meningitis, not elsewhere classified
0.000 0.950 0.050
E27.5 Adrenomedullary hyperfunction
0.000 0.950 0.050
E27.0 Other adrenocortical overactivity
0.000 0.950 0.050
L52 Erythema nodosum
0.000 0.950 0.050
G36.9 Acute disseminated demyelination, unspecified
0.000 0.950 0.050
G36.8 Other specified acute disseminated demyelination
0.000 0.950 0.050
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.950 0.050
L50.9 Urticaria, unspecified
0.000 0.950 0.050
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.950 0.049
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.952 0.048
K93.1 Megacolon in Chagas' disease
0.000 0.952 0.048
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.952 0.048
L13 Other bullous disorders
0.000 0.952 0.048
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.952 0.048
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.047 0.952 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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