TreeWAS – Variant ID: rs77988765

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.024	0.976	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.981	0.019
L03.3 Cellulitis of trunk	0.013	0.987	0.000
I95.1 Orthostatic hypotension	0.009	0.991	0.000
I10-I15 Hypertensive diseases	0.009	0.991	0.000
M17.9 Gonarthrosis, unspecified	0.000	0.992	0.008
I15 Secondary hypertension	0.007	0.993	0.000
J00 Acute nasopharyngitis [common cold]	0.007	0.993	0.000
I13 Hypertensive heart and renal disease	0.006	0.994	0.000
I15.0 Renovascular hypertension	0.006	0.994	0.000
I11 Hypertensive heart disease	0.006	0.994	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.006	0.994	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.994	0.006
I15.9 Seconday hypertension, unspecified	0.006	0.994	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
I15.8 Other secondary hypertension	0.005	0.994	0.000
I15.2 Hypertension secondary to endocrine disorders	0.005	0.994	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
I15.1 Hypertension secondary to other renal disorders	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.005	0.995	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.005	0.995	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.005	0.995	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.005	0.995	0.000
I95 Hypotension	0.005	0.995	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.005	0.995	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.005	0.995	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.005	0.995	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.995	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.004	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.996	0.004
Y42.5 Other oestrogens and progestogens	0.000	0.996	0.004
I12 Hypertensive renal disease	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
H54.4 Blindness, one eye	0.000	0.996	0.004
Z46 Fitting and adjustment of other devices	0.000	0.996	0.004
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.996	0.000
I95.0 Idiopathic hypotension	0.004	0.996	0.000
I95.2 Hypotension due to drugs	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.996	0.004
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.000	0.996	0.004
I97.1 Other functional disturbances following cardiac surgery	0.003	0.996	0.000
I99 Other and unspecified disorders of circulatory system	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
H54 Blindness and low vision	0.000	0.997	0.003
I97.9 Postprocedural disorder of circulatory system, unspecified	0.003	0.997	0.000
I97.0 Postcardiotomy syndrome	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
I95.8 Other hypotension	0.003	0.997	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.003	0.997	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.000	0.997	0.003
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.000	0.997	0.003
Z46.4 Fitting and adjustment of orthodontic device	0.000	0.997	0.003
Z46.1 Fitting and adjustment of hearing aid	0.000	0.997	0.003
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.000	0.997	0.003
G25.3 Myoclonus	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.000	0.997	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.000	0.997	0.003
G25.8 Other specified extrapyramidal and movement disorders	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
Z46.8 Fitting and adjustment of other specified devices	0.000	0.997	0.003
D32.9 Meninges, unspecified	0.003	0.997	0.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.997	0.003
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I98.0 Cardiovascular syphilis	0.003	0.997	0.000
N02.8 Other	0.000	0.997	0.003
H54.6 Unqualified visual loss, one eye	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
H54.2 Low vision, both eyes	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
I46.0 Cardiac arrest with successful resuscitation	0.000	0.997	0.003
D86 Sarcoidosis	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
R10.2 Pelvic and perineal pain	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.000	0.997	0.002
Y42.4 Oral contraceptives	0.000	0.997	0.002
Y42.2 Antithyroid drugs	0.000	0.997	0.002
S52.50 Fracture of lower end of radius (closed)	0.000	0.998	0.002
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.002	0.998	0.000
M17.5 Other secondary gonarthrosis	0.000	0.998	0.002
G25.0 Essential tremor	0.002	0.998	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.002
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
L03.8 Cellulitis of other sites	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.002	0.998	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.998	0.002
L03 Cellulitis	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
Z89 Acquired absence of limb	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
J00-J06 Acute upper respiratory infections	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.001	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
Y46.5 Valproic acid	0.001	0.998	0.000
Y46.3 Deoxybarbiturates	0.001	0.998	0.000
Y46.1 Oxazolidinediones	0.001	0.998	0.000
Y46.0 Succinimides	0.001	0.998	0.000
L53.9 Erythematous condition, unspecified	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.998	0.002
Y53.4 Other laxatives	0.001	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.001
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.998	0.001
L27.8 Dermatitis due to other substances taken internally	0.000	0.998	0.001
L27.2 Dermatitis due to ingested food	0.000	0.998	0.001
R26.2 Difficulty in walking, not elsewhere classified	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
J01 Acute sinusitis	0.002	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.998	0.002
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
R30.0 Dysuria	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.998	0.000
G82.5 Tetraplegia, unspecified	0.001	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.998	0.000
L03.9 Cellulitis, unspecified	0.001	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y41.0 Sulphonamides	0.001	0.998	0.000
Y45.1 Salicylates	0.001	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.001	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.001
J39.2 Other diseases of pharynx	0.000	0.998	0.002
L03.0 Cellulitis of finger and toe	0.001	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.001
Y41.5 Antiviral drugs	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
I46 Cardiac arrest	0.000	0.998	0.001
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.001
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.998	0.001
Z57 Occupational exposure to risk-factors	0.000	0.998	0.001
G57.8 Other mononeuropathies of lower limb	0.001	0.999	0.000
N13 Obstructive and reflux uropathy	0.000	0.999	0.001
Q21.1 Atrial septal defect	0.001	0.999	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
J04 Acute laryngitis and tracheitis	0.001	0.999	0.000
S82.00 Fracture of patella (closed)	0.000	0.999	0.001
K81.0 Acute cholecystitis	0.001	0.999	0.000
Y43.4 Immunosuppressive agents	0.001	0.999	0.000
D83 Common variable immunodeficiency	0.001	0.999	0.000
J03 Acute tonsillitis	0.001	0.999	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.999	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.001	0.999	0.000
J01.9 Acute sinusitis, unspecified	0.001	0.999	0.000
J01.0 Acute maxillary sinusitis	0.001	0.999	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.999	0.001
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.999	0.001
J01.8 Other acute sinusitis	0.001	0.999	0.000
J01.4 Acute pansinusitis	0.001	0.999	0.000
J01.3 Acute sphenoidal sinusitis	0.001	0.999	0.000
J01.2 Acute ethmoidal sinusitis	0.001	0.999	0.000
J01.1 Acute frontal sinusitis	0.001	0.999	0.000
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
W18.3 Sports and athletics area	0.000	0.999	0.001
D84 Other immunodeficiencies	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
F05.9 Delirium, unspecified	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.999	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
Z35.5 Supervision of elderly primigravida	0.001	0.999	0.000
Z90.3 Acquired absence of part of stomach	0.001	0.999	0.000
D09.0 Bladder	0.000	0.999	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
J05.0 Acute obstructive laryngitis [croup]	0.001	0.999	0.000
N13.4 Hydroureter	0.000	0.999	0.001
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.999	0.001
Z57.8 Occupational exposure to other risk-factors	0.000	0.999	0.001
Z57.7 Occupational exposure to vibration	0.000	0.999	0.001
Z57.6 Occupational exposure to extreme temperature	0.000	0.999	0.001
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.999	0.001
Z57.1 Occupational exposure to radiation	0.000	0.999	0.001
Z57.0 Occupational exposure to noise	0.000	0.999	0.001
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.999	0.001
I71 Aortic aneurysm and dissection	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
J04.2 Acute laryngotracheitis	0.001	0.999	0.000
J05.1 Acute epiglottitis	0.001	0.999	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.999	0.001
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.999	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.001	0.999	0.000
J03.0 Streptococcal tonsillitis	0.001	0.999	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.999	0.000
Y45.4 Antirheumatics	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.999	0.000
A87.9 Viral meningitis, unspecified	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
J04.0 Acute laryngitis	0.001	0.999	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
N13.6 Pyonephrosis	0.000	0.999	0.001
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.999	0.001
T79.5 Traumatic anuria	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.000	0.999	0.001
Y44.2 Anticoagulants	0.001	0.999	0.000
C69.3 Choroid	0.001	0.999	0.000
U51 Admission status on psychiatric patients	0.000	0.999	0.001
J04.1 Acute tracheitis	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.999	0.001
J02 Acute pharyngitis	0.001	0.999	0.000
O70 Perineal laceration during delivery	0.000	0.999	0.001
M47.92 Spondylosis, unspecified (Cervical region)	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
J02.0 Streptococcal pharyngitis	0.001	0.999	0.000
K55.2 Angiodysplasia of colon	0.001	0.999	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.999	0.001
Z98.8 Other specified postsurgical states	0.001	0.999	0.000
S22.20 Fracture of sternum (closed)	0.001	0.999	0.000
C79.2 Secondary malignant neoplasm of skin	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
M17.1 Other primary gonarthrosis	0.000	0.999	0.001
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.999	0.001
T79 Certain early complications of trauma, not elsewhere classified	0.001	0.999	0.000
G51.3 Clonic hemifacial spasm	0.001	0.999	0.000
G51.0 Bell's palsy	0.001	0.999	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.999	0.001
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.001	0.999	0.000
M24.6 Ankylosis of joint	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.999	0.001
K72 Hepatic failure, not elsewhere classified	0.000	0.999	0.001
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
G51.9 Disorder of facial nerve, unspecified	0.001	0.999	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations