TreeWAS – Variant ID: rs7812879

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.825	0.175
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.830	0.170
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.834	0.166
Y83.3 Surgical operation with formation of external stoma	0.000	0.841	0.159
Y83.0 Surgical operation with transplant of whole organ	0.000	0.855	0.145
Y83.4 Other reconstructive surgery	0.000	0.866	0.134
Y83.9 Surgical procedure, unspecified	0.000	0.867	0.133
Y83.5 Amputation of limb(s)	0.000	0.892	0.108
Y83.8 Other surgical procedures	0.000	0.910	0.090
Y83.6 Removal of other organ (partial) (total)	0.000	0.931	0.069
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.953	0.047
I35.0 Aortic (valve) stenosis	0.000	0.975	0.025
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.978	0.022
Y84.4 Aspiration of fluid	0.000	0.980	0.020
Z48.0 Attention to surgical dressings and sutures	0.000	0.980	0.020
Z48.8 Other specified surgical follow-up care	0.000	0.981	0.019
Z48 Other surgical follow-up care	0.000	0.982	0.018
Y84.1 Kidney dialysis	0.000	0.983	0.017
E87.6 Hypokalaemia	0.000	0.983	0.017
Y84.5 Insertion of gastric or duodenal sound	0.000	0.983	0.016
Y84.3 Shock therapy	0.000	0.984	0.016
Y84.9 Medical procedure, unspecified	0.000	0.984	0.016
Y84.7 Blood-sampling	0.000	0.984	0.016
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.984	0.016
M16.9 Coxarthrosis, unspecified	0.000	0.984	0.016
Y84.6 Urinary catheterisation	0.000	0.985	0.015
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.986	0.014
E87.7 Fluid overload	0.000	0.986	0.014
Z48.9 Surgical follow-up care, unspecified	0.000	0.986	0.014
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.986	0.014
E87.5 Hyperkalaemia	0.000	0.986	0.014
E87.2 Acidosis	0.000	0.987	0.013
E87.3 Alkalosis	0.000	0.988	0.012
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.988	0.012
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.988	0.012
E87.4 Mixed disorder of acid-base balance	0.000	0.988	0.011
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.011	0.989	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.989	0.011
T43.3 Phenothiazine antipsychotics and neuroleptics	0.011	0.989	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.989	0.010
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.990	0.010
E66.9 Obesity, unspecified	0.000	0.990	0.010
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
Y84.8 Other medical procedures	0.000	0.990	0.010
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.990	0.010
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.991	0.009
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.008	0.992	0.000
T40.2 Other opioids	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
H54.4 Blindness, one eye	0.000	0.992	0.008
I35 Nonrheumatic aortic valve disorders	0.000	0.992	0.008
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.992	0.008
T39.1 4-Aminophenol derivatives	0.008	0.992	0.000
Y84.0 Cardiac catheterisation	0.000	0.992	0.008
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
H54 Blindness and low vision	0.000	0.992	0.008
T36 Poisoning by systemic antibiotics	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.993	0.007
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
H54.0 Blindness, both eyes	0.000	0.993	0.007
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.993	0.007
T40.5 Cocaine	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.993	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.994	0.006
T40.1 Heroin	0.006	0.994	0.000
E03.9 Hypothyroidism, unspecified	0.006	0.994	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.994	0.000
T40.8 Lysergide [LSD]	0.006	0.994	0.000
T40.7 Cannabis (derivatives)	0.006	0.994	0.000
T40.0 Opium	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.994	0.006
T36.0 Penicillins	0.006	0.994	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.994	0.006
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.994	0.006
T36.3 Macrolides	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T40.3 Methadone	0.006	0.994	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.994	0.006
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
H54.2 Low vision, both eyes	0.000	0.994	0.006
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.994	0.005
T39.0 Salicylates	0.006	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.994	0.000
T50.5 Appetite depressants	0.005	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.994	0.000
T21 Burn and corrosion of trunk	0.000	0.994	0.006
H54.5 Low vision, one eye	0.000	0.994	0.005
T47.6 Antidiarrhoeal drugs	0.005	0.994	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.994	0.006
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.994	0.000
I35.8 Other aortic valve disorders	0.000	0.995	0.005
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.995	0.005
E66 Obesity	0.000	0.995	0.005
H54.1 Blindness, one eye, low vision, other eye	0.000	0.995	0.005
T45.5 Anticoagulants	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.995	0.005
T21.0 Burn of unspecified degree of trunk	0.000	0.995	0.005
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
E66.8 Other obesity	0.000	0.995	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
M25.51 Pain in joint (Shoulder region)	0.005	0.995	0.000
H54.7 Unspecified visual loss	0.000	0.995	0.005
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T21.3 Burn of third degree of trunk	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.005	0.995	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.995	0.005
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T25 Burn and corrosion of ankle and foot	0.000	0.995	0.005
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T21.2 Burn of second degree of trunk	0.000	0.995	0.005
T47.4 Other laxatives	0.004	0.995	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.995	0.000
T21.1 Burn of first degree of trunk	0.000	0.995	0.004
H70.9 Mastoiditis, unspecified	0.000	0.995	0.005
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.996	0.004
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.000	0.996	0.004
T25.2 Burn of second degree of ankle and foot	0.000	0.996	0.004
T21.7 Corrosion of third degree of trunk	0.000	0.996	0.004
T21.6 Corrosion of second degree of trunk	0.000	0.996	0.004
T21.5 Corrosion of first degree of trunk	0.000	0.996	0.004
T21.4 Corrosion of unspecified degree of trunk	0.000	0.996	0.004
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T20 Burn and corrosion of head and neck	0.000	0.996	0.004
T82.3 Mechanical complication of other vascular grafts	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.000	0.996	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
T20.2 Burn of second degree of head and neck	0.000	0.996	0.004
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
S22.40 Multiple fractures of ribs (closed)	0.004	0.996	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
E66.0 Obesity due to excess calories	0.000	0.996	0.004
T42.3 Barbiturates	0.003	0.996	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T25.7 Corrosion of third degree of ankle and foot	0.000	0.996	0.004
T25.6 Corrosion of second degree of ankle and foot	0.000	0.996	0.004
T25.5 Corrosion of first degree of ankle and foot	0.000	0.996	0.004
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.996	0.004
T25.1 Burn of first degree of ankle and foot	0.000	0.996	0.004
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.003
Y84.2 Radiological procedure and radiotherapy	0.001	0.996	0.003
T25.3 Burn of third degree of ankle and foot	0.000	0.996	0.003
T42.1 Iminostilbenes	0.003	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.996	0.000
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
E03 Other hypothyroidism	0.003	0.997	0.000
T20.3 Burn of third degree of head and neck	0.000	0.997	0.003
H70 Mastoiditis and related conditions	0.000	0.997	0.003
T20.7 Corrosion of third degree of head and neck	0.000	0.997	0.003
T20.6 Corrosion of second degree of head and neck	0.000	0.997	0.003
T20.5 Corrosion of first degree of head and neck	0.000	0.997	0.003
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.997	0.003
M25.57 Pain in joint (Ankle and foot)	0.000	0.997	0.003
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
T20.1 Burn of first degree of head and neck	0.000	0.997	0.003
T86.0 Bone-marrow transplant rejection	0.000	0.997	0.003
N39.9 Disorder of urinary system, unspecified	0.000	0.997	0.003
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.997	0.003
T23 Burn and corrosion of wrist and hand	0.000	0.997	0.003
T86.1 Kidney transplant failure and rejection	0.000	0.997	0.003
T86 Failure and rejection of transplanted organs and tissues	0.000	0.997	0.003
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
E03.0 Congenital hypothyroidism with diffuse goitre	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
H70.1 Chronic mastoiditis	0.000	0.997	0.003
R40.0 Somnolence	0.000	0.997	0.003
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
H70.0 Acute mastoiditis	0.000	0.997	0.003
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
K91.4 Colostomy and enterostomy malfunction	0.000	0.997	0.003
E03.5 Myxoedema coma	0.002	0.997	0.000
E03.4 Atrophy of thyroid (acquired)	0.002	0.997	0.000
E03.3 Postinfectious hypothyroidism	0.002	0.997	0.000
F32.1 Moderate depressive episode	0.003	0.997	0.000
H70.2 Petrositis	0.000	0.997	0.003
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.002
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.002
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.997	0.002
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
T86.4 Liver transplant failure and rejection	0.000	0.997	0.002
E04 Other non-toxic goitre	0.000	0.997	0.002
H65-H75 Diseases of middle ear and mastoid	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.998	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.998	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.998	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.998	0.002
K26 Duodenal ulcer	0.000	0.998	0.002
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.002
F32.0 Mild depressive episode	0.002	0.998	0.000
E03.1 Congenital hypothyroidism without goitre	0.002	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.000	0.998	0.002
T86.2 Heart transplant failure and rejection	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
K26.1 Acute with perforation	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
K26.0 Acute with haemorrhage	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
K56.7 Ileus, unspecified	0.000	0.998	0.002
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.998	0.001
H73.1 Chronic myringitis	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.998	0.002
Z88.5 Personal history of allergy to narcotic agent	0.000	0.998	0.002
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H67 Otitis media in diseases classified elsewhere	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
K26.2 Acute with both haemorrhage and perforation	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
H81 Disorders of vestibular function	0.000	0.998	0.002
K01.1 Impacted teeth	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.000	0.998	0.002
K26.5 Chronic or unspecified with perforation	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.001
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
N95.1 Menopausal and female climacteric states	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
K26.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
J47 Bronchiectasis	0.000	0.998	0.002
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
D64.9 Anaemia, unspecified	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
L43 Lichen planus	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.002
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.002
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.002
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
M16.5 Other posttraumatic coxarthrosis	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.000	0.998	0.002
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.000	0.998	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.000	0.998	0.001
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
L43.8 Other lichen planus	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.001
X62.9 Unspecified place	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.000	0.998	0.001
E67.3 Hypervitaminosis D	0.000	0.998	0.001
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.001
E67.1 Hypercarotenaemia	0.000	0.998	0.001
E67.0 Hypervitaminosis A	0.000	0.998	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
Z84.8 Family history of other specified conditions	0.000	0.998	0.002
M16 Coxarthrosis [arthrosis of hip]	0.000	0.998	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
D11.0 Parotid gland	0.002	0.998	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.998	0.001
L43.3 Subacute (active) lichen planus	0.001	0.998	0.000
L43.2 Lichenoid drug reaction	0.001	0.998	0.000
L43.1 Bullous lichen planus	0.001	0.998	0.000
F32 Depressive episode	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
F10.1 Harmful use	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.999	0.001
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.999	0.001
T90 Sequelae of injuries of head	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.000	0.999	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.999	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.001	0.999	0.000
K91.1 Postgastric surgery syndromes	0.000	0.999	0.001
T31.0 Burns involving less than 10% of body surface	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
H81.2 Vestibular neuronitis	0.000	0.999	0.001
L43.0 Hypertrophic lichen planus	0.001	0.999	0.000
M16.3 Other dysplastic coxarthrosis	0.000	0.999	0.001
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.999	0.001
E11.2 With renal complications	0.000	0.999	0.001
J32.9 Chronic sinusitis, unspecified	0.000	0.999	0.001
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.999	0.001
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.999	0.001
Z01.6 Radiological examination, not elsewhere classified	0.001	0.999	0.000
E65 Localised adiposity	0.000	0.999	0.001
F32.8 Other depressive episodes	0.001	0.999	0.000
L03.0 Cellulitis of finger and toe	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.000	0.999	0.001
S43.0 Dislocation of shoulder joint	0.001	0.999	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.999	0.001
Z94.2 Lung transplant status	0.000	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.999	0.001
E83.3 Disorders of phosphorus metabolism	0.000	0.999	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
J35.0 Chronic tonsillitis	0.000	0.999	0.001
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
H53-H54 Visual disturbances and blindness	0.000	0.999	0.001
E73.9 Lactose intolerance, unspecified	0.000	0.999	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.001	0.999	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.999	0.001
Z94.7 Corneal transplant status	0.000	0.999	0.001
Z94.1 Heart transplant status	0.000	0.999	0.001
J35 Chronic diseases of tonsils and adenoids	0.000	0.999	0.001
R40 Somnolence, stupor and coma	0.000	0.999	0.001
H34.8 Other retinal vascular occlusions	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.999	0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.999	0.001
X23.8 Other specified place	0.000	0.999	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
X23.9 Unspecified place	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
D84.1 Defects in the complement system	0.000	0.999	0.001
K91.5 Postcholecystectomy syndrome	0.000	0.999	0.001
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.999	0.001
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.999	0.001
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.999	0.001
T90.1 Sequelae of open wound of head	0.000	0.999	0.001
D33.3 Cranial nerves	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations