TreeWAS – Variant ID: rs7825175

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.404	0.596	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.400	0.600	0.000
E00-E07 Disorders of thyroid gland	0.385	0.615	0.000
E04 Other non-toxic goitre	0.383	0.617	0.000
E06 Thyroiditis	0.375	0.625	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.371	0.629	0.000
E04.9 Non-toxic goitre, unspecified	0.347	0.653	0.000
E06.3 Autoimmune thyroiditis	0.347	0.653	0.000
E04.1 Non-toxic single thyroid nodule	0.342	0.658	0.000
E04.0 Non-toxic diffuse goitre	0.338	0.662	0.000
E06.9 Thyroiditis, unspecified	0.335	0.665	0.000
E04.2 Non-toxic multinodular goitre	0.311	0.689	0.000
E06.5 Other chronic thyroiditis	0.297	0.703	0.000
E05.5 Thyroid crisis or storm	0.287	0.713	0.000
E05.4 Thyrotoxicosis factitia	0.287	0.713	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.287	0.713	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.287	0.713	0.000
E05.8 Other thyrotoxicosis	0.279	0.721	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.276	0.724	0.000
E00 Congenital iodine-deficiency syndrome	0.276	0.724	0.000
E04.8 Other specified non-toxic goitre	0.274	0.725	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.273	0.727	0.000
E06.4 Drug-induced thyroiditis	0.269	0.731	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.269	0.731	0.000
E06.1 Subacute thyroiditis	0.269	0.731	0.000
E06.0 Acute thyroiditis	0.269	0.731	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.263	0.737	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.198	0.802	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.198	0.802	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.198	0.802	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.198	0.802	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.198	0.802	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.198	0.802	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.198	0.802	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.198	0.802	0.000
E07 Other disorders of thyroid	0.181	0.819	0.000
E07.1 Dyshormogenetic goitre	0.130	0.870	0.000
E07.0 Hypersecretion of calcitonin	0.130	0.870	0.000
E07.8 Other specified disorders of thyroid	0.108	0.892	0.000
E03 Other hypothyroidism	0.079	0.921	0.000
E07.9 Disorder of thyroid, unspecified	0.078	0.922	0.000
E03.1 Congenital hypothyroidism without goitre	0.062	0.938	0.000
E03.5 Myxoedema coma	0.057	0.943	0.000
E03.4 Atrophy of thyroid (acquired)	0.057	0.943	0.000
E03.3 Postinfectious hypothyroidism	0.057	0.943	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.057	0.943	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.038	0.962	0.001
E03.8 Other specified hypothyroidism	0.035	0.964	0.001
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.973	0.027
C73 Malignant neoplasm of thyroid gland	0.018	0.982	0.000
S72.00 Fracture of neck of femur (closed)	0.010	0.990	0.000
L43.9 Lichen planus, unspecified	0.000	0.990	0.010
E89.0 Postprocedural hypothyroidism	0.008	0.992	0.000
H11.0 Pterygium	0.008	0.992	0.000
H11 Other disorders of conjunctiva	0.008	0.992	0.000
H11.1 Conjunctival degenerations and deposits	0.008	0.992	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.008	0.992	0.000
H11.2 Conjunctival scars	0.007	0.993	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.007	0.993	0.000
H11.8 Other specified disorders of conjunctiva	0.006	0.994	0.000
L43 Lichen planus	0.000	0.994	0.006
H11.9 Disorder of conjunctiva, unspecified	0.006	0.994	0.000
H11.3 Conjunctival haemorrhage	0.006	0.994	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.994	0.006
C74 Malignant neoplasm of adrenal gland	0.006	0.994	0.000
L43.8 Other lichen planus	0.000	0.994	0.006
C75 Malignant neoplasm of other endocrine glands and related structures	0.006	0.994	0.000
S72.0 Fracture of neck of femur	0.005	0.995	0.000
I35.0 Aortic (valve) stenosis	0.000	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
L43.3 Subacute (active) lichen planus	0.000	0.995	0.005
L43.2 Lichenoid drug reaction	0.000	0.995	0.005
L43.1 Bullous lichen planus	0.000	0.995	0.005
L43.0 Hypertrophic lichen planus	0.000	0.995	0.005
S01.8 Open wound of other parts of head	0.005	0.995	0.000
C74.9 Adrenal gland, unspecified	0.004	0.995	0.000
C74.1 Medulla of adrenal gland	0.004	0.995	0.000
C74.0 Cortex of adrenal gland	0.004	0.995	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.005	0.995	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.005	0.995	0.000
C75.9 Endocrine gland, unspecified	0.004	0.996	0.000
C75.8 Pluriglandular involvement, unspecified	0.004	0.996	0.000
C75.5 Aortic body and other paraganglia	0.004	0.996	0.000
C75.4 Carotid body	0.004	0.996	0.000
C75.3 Pineal gland	0.004	0.996	0.000
C75.2 Craniopharyngeal duct	0.004	0.996	0.000
C75.1 Pituitary gland	0.004	0.996	0.000
C75.0 Parathyroid gland	0.004	0.996	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.004	0.996	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.996	0.004
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
R00.1 Bradycardia, unspecified	0.004	0.996	0.000
S72.01 Fracture of neck of femur (open)	0.004	0.996	0.000
L89.1 Stage II decubitus ulcer	0.004	0.996	0.000
H10-H13 Disorders of conjunctiva	0.004	0.996	0.000
E40-E46 Malnutrition	0.004	0.996	0.000
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
E87.7 Fluid overload	0.000	0.996	0.004
L89 Decubitus ulcer	0.004	0.996	0.000
N76.4 Abscess of vulva	0.000	0.996	0.004
N76.0 Acute vaginitis	0.000	0.996	0.004
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.996	0.004
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.997	0.003
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.997	0.003
C78.4 Secondary malignant neoplasm of small intestine	0.003	0.997	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
L89.3 Stage IV decubitus ulcer	0.003	0.997	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.003	0.997	0.000
C78.7 Secondary malignant neoplasm of liver	0.003	0.997	0.000
H10 Conjunctivitis	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
E58 Dietary calcium deficiency	0.003	0.997	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
H13 Disorders of conjunctiva in diseases classified elsewhere	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.003	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.003	0.997	0.000
E42 Marasmic kwashiorkor	0.003	0.997	0.000
E41 Nutritional marasmus	0.003	0.997	0.000
E40 Kwashiorkor	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.003	0.997	0.000
E50 Vitamin A deficiency	0.003	0.997	0.000
E60 Dietary zinc deficiency	0.003	0.997	0.000
E59 Dietary selenium deficiency	0.003	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
E52 Niacin deficiency [pellagra]	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
I78 Diseases of capillaries	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
N76 Other inflammation of vagina and vulva	0.000	0.997	0.003
H10.4 Chronic conjunctivitis	0.003	0.997	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.997	0.003
C18.0 Caecum	0.003	0.997	0.000
W02.9 Unspecified place	0.000	0.997	0.003
E55 Vitamin D deficiency	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.003	0.997	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
K76.6 Portal hypertension	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.000	0.997	0.003
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.997	0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.000	0.997	0.003
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.003	0.997	0.000
H10.8 Other conjunctivitis	0.002	0.997	0.000
H10.5 Blepharoconjunctivitis	0.002	0.997	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.997	0.000
H10.2 Other acute conjunctivitis	0.002	0.997	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.997	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.997	0.000
E51.1 Beriberi	0.002	0.997	0.000
N76.5 Ulceration of vagina	0.000	0.997	0.002
S92.5 Fracture of other toe	0.003	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.997	0.000
C18.9 Colon, unspecified	0.003	0.997	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.997	0.000
H13.3 Ocular pemphigoid	0.002	0.997	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.997	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.997	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.997	0.002
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
E55.0 Rickets, active	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
Z63 Other problems related to primary support group, including family circumstances	0.000	0.998	0.002
E10-E14 Diabetes mellitus	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.000	0.998	0.002
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.000	0.998	0.002
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.000	0.998	0.002
Z90.7 Acquired absence of genital organ(s)	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
N18 Chronic renal failure	0.000	0.998	0.002
C18.5 Splenic flexure	0.002	0.998	0.000
E87.2 Acidosis	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.998	0.002
A40.1 Septicaemia due to streptococcus, group B	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
Z63.9 Problem related to primary support group, unspecified	0.000	0.998	0.002
Z63.3 Absence of family member	0.000	0.998	0.002
Z63.2 Inadequate family support	0.000	0.998	0.002
Z63.1 Problems in relationship with parents and in-laws	0.000	0.998	0.002
E12 Malnutrition-related diabetes mellitus	0.002	0.998	0.000
C18.6 Descending colon	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
M10.92 Gout, unspecified (Upper arm)	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
Z63.5 Disruption of family by separation and divorce	0.000	0.998	0.002
E67 Other hyperalimentation	0.002	0.998	0.000
E68 Sequelae of hyperalimentation	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.000	0.998	0.002
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.002
A40 Streptococcal septicaemia	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.998	0.000
N48.1 Balanoposthitis	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
G44.2 Tension-type headache	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.002
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.998	0.002
A40.8 Other streptococcal septicaemia	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.001	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.002	0.998	0.000
E87.6 Hypokalaemia	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.002
Z57.7 Occupational exposure to vibration	0.000	0.998	0.002
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.002
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.002
Z57.1 Occupational exposure to radiation	0.000	0.998	0.002
Z57.0 Occupational exposure to noise	0.000	0.998	0.002
Z63.4 Disappearance and death of family member	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
H44.0 Purulent endophthalmitis	0.000	0.998	0.002
N18.1 Chronic kidney disease, stage 1	0.000	0.998	0.002
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.998	0.000
Q51.4 Unicornate uterus	0.001	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.001	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.002	0.998	0.000
E12.9 Without complications	0.001	0.998	0.000
E12.8 With unspecified complications	0.001	0.998	0.000
E12.7 With multiple complications	0.001	0.998	0.000
E12.6 With other specified complications	0.001	0.998	0.000
E12.5 With peripheral circulatory complications	0.001	0.998	0.000
E12.4 With neurological complications	0.001	0.998	0.000
E12.3 With ophthalmic complications	0.001	0.998	0.000
E12.2 With renal complications	0.001	0.998	0.000
E12.1 With ketoacidosis	0.001	0.998	0.000
E12.0 With coma	0.001	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.001	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
E67.8 Other specified hyperalimentation	0.001	0.998	0.000
E67.3 Hypervitaminosis D	0.001	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.001	0.998	0.000
E67.1 Hypercarotenaemia	0.001	0.998	0.000
E67.0 Hypervitaminosis A	0.001	0.998	0.000
E65 Localised adiposity	0.001	0.998	0.000
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.001	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
M10.9 Gout, unspecified	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
A40.2 Septicaemia due to streptococcus, group D	0.001	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.001
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.001	0.998	0.000
B00.5 Herpesviral ocular disease	0.001	0.998	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.998	0.001
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.998	0.001
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.001	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.001
I42.8 Other cardiomyopathies	0.001	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.998	0.000
S72.7 Multiple fractures of femur	0.001	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
E11.4 With neurological complications	0.001	0.999	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.999	0.001
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
E14 Unspecified diabetes mellitus	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.999	0.000
C78.0 Secondary malignant neoplasm of lung	0.001	0.999	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
Z46.8 Fitting and adjustment of other specified devices	0.001	0.999	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.001	0.999	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.999	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.999	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
E14.5 With peripheral circulatory complications	0.001	0.999	0.000
E14.2 Withrenal complications	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.999	0.001
E88 Other metabolic disorders	0.001	0.999	0.000
M10.98 Gout, unspecified (Other)	0.001	0.999	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M10.91 Gout, unspecified (Shoulder region)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
B00.8 Other forms of herpesviral infection	0.001	0.999	0.000
B00.7 Disseminated herpesviral disease	0.001	0.999	0.000
B00.3 Herpesviral meningitis	0.001	0.999	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.999	0.000
B00.0 Eczema herpeticum	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations