TreeWAS – Variant ID: rs7828135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O60-O75 Complications of labour and delivery	0.032	0.968
O75 Other complications of labour and delivery, not elsewhere classified	0.030	0.970
O63 Long labour	0.030	0.970
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.029	0.971
T36-T50 Poisoning by drugs, medicaments and biological substances	0.028	0.972
Chapter XV Pregnancy, childbirth and the puerperium	0.028	0.972
O63.1 Prolonged second stage (of labour)	0.028	0.972
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.028	0.972
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.027	0.973
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.027	0.973
O68 Labour and delivery complicated by foetal stress [distress]	0.026	0.974
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.026	0.974
O72 Postpartum haemorrhage	0.026	0.974
O66 Other obstructed labour	0.026	0.974
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.025	0.975
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.025	0.975
T39.1 4-Aminophenol derivatives	0.025	0.975
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.025	0.975
O62 Abnormalities of forces of labour	0.025	0.975
O64 Obstructed labour due to malposition and malpresentation of foetus	0.025	0.975
O63.0 Prolonged first stage (of labour)	0.025	0.975
O73 Retained placenta and membranes, without haemorrhage	0.024	0.976
O36 Maternal care for other known or suspected foetal problems	0.024	0.976
O16 Unspecified maternal hypertension	0.023	0.977
O61 Failed induction of labour	0.023	0.977
O75.0 Maternal distress during labour and delivery	0.023	0.977
T39.0 Salicylates	0.023	0.977
O74 Complications of anaesthesia during labour and delivery	0.023	0.977
O71 Other obstetric trauma	0.023	0.977
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.023	0.977
O65 Obstructed labour due to maternal pelvic abnormality	0.023	0.977
O60 Preterm delivery	0.023	0.977
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.023	0.977
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.023	0.977
T43.2 Other and unspecified antidepressants	0.023	0.977
T66-T78 Other and unspecified effects of external causes	0.023	0.977
O75.2 Pyrexia during labour, not elsewhere classified	0.023	0.977
O75.8 Other specified complications of labour and delivery	0.022	0.978
O00-O08 Pregnancy with abortive outcome	0.022	0.978
S10-S19 Injuries to the neck	0.022	0.978
O36.9 Maternal care for foetal problem, unspecified	0.022	0.978
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.022	0.978
O72.1 Other immediate postpartum haemorrhage	0.022	0.978
O75.9 Complication of labour and delivery, unspecified	0.021	0.978
O75.5 Delayed delivery after artificial rupture of membranes	0.021	0.978
O75.4 Other complications of obstetric surgery and procedures	0.021	0.978
O75.3 Other infection during labour	0.021	0.978
O75.1 Shock during or following labour and delivery	0.021	0.978
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.022	0.978
O63.2 Delayed delivery of second twin, triplet, etc.	0.021	0.978
S20-S29 Injuries to the thorax	0.021	0.978
O69 Labour and delivery complicated by umbilical cord complications	0.021	0.979
O75.7 Vaginal delivery following previous Caesarean section	0.021	0.979
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.021	0.979
O46 Antepartum haemorrhage, not elsewhere classified	0.021	0.979
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.021	0.979
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.021	0.979
T39.4 Antirheumatics, not elsewhere classified	0.021	0.979
T39.2 Pyrazolone derivatives	0.021	0.979
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.021	0.979
Z13.9 Special screening examination, unspecified	0.021	0.979
O20-O29 Other maternal disorders predominantly related to pregnancy	0.021	0.979
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.021	0.979
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.020	0.979
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.020	0.979
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.020	0.979
T46 Poisoning by agents primarily affecting the cardiovascular system	0.020	0.979
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.020	0.979
T41 Poisoning by anaesthetics and therapeutic gases	0.020	0.979
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.020	0.979
T36 Poisoning by systemic antibiotics	0.020	0.979
O63.9 Long labour, unspecified	0.020	0.980
O85-O92 Complications predominantly related to the puerperium	0.020	0.980
O72.0 Third-stage haemorrhage	0.020	0.980
T78 Adverse effects, not elsewhere classified	0.020	0.980
T43.3 Phenothiazine antipsychotics and neuroleptics	0.020	0.980
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.020	0.980
O32 Maternal care for known or suspected malpresentation of foetus	0.020	0.980
O80-O84 Delivery	0.020	0.980
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.020	0.980
S90-S99 Injuries to the ankle and foot	0.020	0.980
O62.0 Primary inadequate contractions	0.020	0.980
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.020	0.980
O36.8 Maternal care for other specified foetal problems	0.020	0.980
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.019	0.980
O35 Maternal care for known or suspected foetal abnormality and damage	0.019	0.981
O73.0 Retained placenta, without haemorrhage	0.019	0.981
S70-S79 Injuries to the hip and thigh	0.019	0.981
S22 Fracture of rib(s), sternum and thoracic spine	0.019	0.981
O41 Other disorders of amniotic fluid and membranes	0.019	0.981
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.019	0.981
T45.1 Antineoplastic and immunosuppressive drugs	0.019	0.981
T93 Sequelae of injuries of lower limb	0.019	0.981
T43.0 Tricyclic and tetracyclic antidepressants	0.019	0.981
T50.9 Other and unspecified drugs, medicaments and biological substances	0.019	0.981
O15 Eclampsia	0.019	0.981
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.019	0.981
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.019	0.981
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.019	0.981
O62.2 Other uterine inertia	0.019	0.981
O72.3 Postpartum coagulation defects	0.019	0.981
O64.1 Obstructed labour due to breech presentation	0.019	0.981
O66.9 Obstructed labour, unspecified	0.019	0.981
O66.8 Other specified obstructed labour	0.019	0.981
O66.4 Failed trial of labour, unspecified	0.019	0.981
O66.3 Obstructed labour due to other abnormalities of foetus	0.019	0.981
O66.2 Obstructed labour due to unusually large foetus	0.019	0.981
O66.1 Obstructed labour due to locked twins	0.019	0.981
O66.0 Obstructed labour due to shoulder dystocia	0.019	0.981
O44 Placenta praevia	0.019	0.981
T70 Effects of air pressure and water pressure	0.019	0.981
T43.9 Psychotropic drug, unspecified	0.018	0.981
T43.8 Other psychotropic drugs, not elsewhere classified	0.018	0.981
T43.6 Psychostimulants with abuse potential	0.018	0.981
T43.4 Butyrophenone and thioxanthene neuroleptics	0.018	0.981
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.018	0.981
O45 Premature separation of placenta [abruptio placentae]	0.018	0.981
O43 Placental disorders	0.018	0.981
O33 Maternal care for known or suspected disproportion	0.018	0.981
O31 Complications specific to multiple gestation	0.018	0.981
O40 Polyhydramnios	0.018	0.981
S80-S89 Injuries to the knee and lower leg	0.018	0.982
O04 Medical abortion	0.018	0.982
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.018	0.982
T79-T79 Certain early complications of trauma	0.018	0.982
T33-T35 Frostbite	0.018	0.982
T26-T28 Burns and corrosions confined to eye and internal organs	0.018	0.982
T20-T25 Burns and corrosions of external body surface, specified by site	0.018	0.982
T00-T07 Injuries involving multiple body regions	0.018	0.982
O62.9 Abnormality of forces of labour, unspecified	0.018	0.982
O62.8 Other abnormalities of forces of labour	0.018	0.982
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.018	0.982
O62.3 Precipitate labour	0.018	0.982
O62.1 Secondary uterine inertia	0.018	0.982
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.018	0.982
O46.9 Antepartum haemorrhage, unspecified	0.018	0.982
O00 Ectopic pregnancy	0.018	0.982
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.018	0.982
O94-O99 Other obstetric conditions, not elsewhere classified	0.018	0.982
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.018	0.982
O64.8 Obstructed labour due to other malposition and malpresentation	0.018	0.982
O64.5 Obstructed labour due to compound presentation	0.018	0.982
O64.4 Obstructed labour due to shoulder presentation	0.018	0.982
O64.3 Obstructed labour due to brow presentation	0.018	0.982
O64.2 Obstructed labour due to face presentation	0.018	0.982
S19 Other and unspecified injuries of neck	0.018	0.982
S30 Superficial injury of abdomen, lower back and pelvis	0.018	0.982
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.018	0.982
O42 Premature rupture of membranes	0.018	0.982
O30 Multiple gestation	0.017	0.982
S12 Fracture of neck	0.017	0.982
O36.0 Maternal care for rhesus isoimmunisation	0.017	0.982
O61.0 Failed medical induction of labour	0.017	0.983
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.017	0.983
O36.4 Maternal care for intra-uterine death	0.017	0.983
O36.3 Maternal care for signs of foetal hypoxia	0.017	0.983
O36.2 Maternal care for hydrops foetalis	0.017	0.983
O36.1 Maternal care for other isoimmunisation	0.017	0.983
O20 Haemorrhage in early pregnancy	0.017	0.983
O47 False labour	0.017	0.983
O36.5 Maternal care for poor foetal growth	0.017	0.983
S10 Superficial injury of neck	0.017	0.983
T94 Sequelae of injuries involving multiple and unspecified body regions	0.017	0.983
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.017	0.983
T43.5 Other and unspecified antipsychotics and neuroleptics	0.017	0.983
T15-T19 Effects of foreign body entering through natural orifice	0.017	0.983
O61.9 Failed induction of labour, unspecified	0.017	0.983
O61.8 Other failed induction of labour	0.017	0.983
O61.1 Failed instrumental induction of labour	0.017	0.983
S22.3 Fracture of rib	0.017	0.983
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.017	0.983
S50-S59 Injuries to the elbow and forearm	0.017	0.983
O36.6 Maternal care for excessive foetal growth	0.017	0.983
S40-S49 Injuries to the shoulder and upper arm	0.017	0.983
O60.3 Preterm delivery without spontaneous labour	0.017	0.983
O60.2 Preterm spontaneous labour with term delivery	0.017	0.983
O60.1 Preterm spontaneous labour with preterm delivery	0.017	0.983
O60.0 Preterm labour without delivery	0.017	0.983
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.017	0.983
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.017	0.983
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.017	0.983
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.017	0.983
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.017	0.983
O65.2 Obstructed labour due to pelvic inlet contraction	0.017	0.983
O65.1 Obstructed labour due to generally contracted pelvis	0.017	0.983
O65.0 Obstructed labour due to deformed pelvis	0.017	0.983
O67.9 Intrapartum haemorrhage, unspecified	0.017	0.983
O67.8 Other intrapartum haemorrhage	0.017	0.983
O67.0 Intrapartum haemorrhage with coagulation defect	0.017	0.983
O71.9 Obstetric trauma, unspecified	0.017	0.983
O71.8 Other specified obstetric trauma	0.017	0.983
O71.7 Obstetric haematoma of pelvis	0.017	0.983
O71.6 Obstetric damage to pelvic joints and ligaments	0.017	0.983
O71.5 Other obstetric injury to pelvic organs	0.017	0.983
O71.4 Obstetric high vaginal laceration alone	0.017	0.983
O71.3 Obstetric laceration of cervix	0.017	0.983
O71.2 Postpartum inversion of uterus	0.017	0.983
O71.1 Rupture of uterus during labour	0.017	0.983
O71.0 Rupture of uterus before onset of labour	0.017	0.983
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.017	0.983
O74.8 Other complications of anaesthesia during labour and delivery	0.017	0.983
O74.7 Failed or difficult intubation during labour and delivery	0.017	0.983
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.017	0.983
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.017	0.983
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.017	0.983
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.017	0.983
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.017	0.983
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.017	0.983
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.017	0.983
O72.2 Delayed and secondary postpartum haemorrhage	0.017	0.983
T45.9 Primarily systemic and haematological agent, unspecified	0.017	0.983
T45.8 Other primarily systemic and haematological agents	0.017	0.983
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.017	0.983
T45.6 Fibrinolysis-affecting drugs	0.017	0.983
T45.5 Anticoagulants	0.017	0.983
T45.4 Iron and its compounds	0.017	0.983
T45.3 Enzymes, not elsewhere classified	0.017	0.983
T45.2 Vitamins, not elsewhere classified	0.017	0.983
T45.0 Antiallergic and antiemetic drugs	0.017	0.983
T50.8 Diagnostic agents	0.017	0.983
T50.7 Analeptics and opioid receptor antagonists	0.017	0.983
T50.6 Antidotes and chelating agents, not elsewhere classified	0.017	0.983
T50.5 Appetite depressants	0.017	0.983
T50.4 Drugs affecting uric acid metabolism	0.017	0.983
T50.3 Electrolytic, caloric and water-balance agents	0.017	0.983
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.017	0.983
T50.1 Loop [high-ceiling] diuretics	0.017	0.983
T50.0 Mineralocorticoids and their antagonists	0.017	0.983
T78.0 Anaphylactic shock due to adverse food reaction	0.017	0.983
T78.3 Angioneurotic oedema	0.017	0.983
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.017	0.983
T75 Effects of other external causes	0.016	0.983
T74 Maltreatment syndromes	0.016	0.983
T73 Effects of other deprivation	0.016	0.983
T69 Other effects of reduced temperature	0.016	0.983
T67 Effects of heat and light	0.016	0.983
T71 Asphyxiation	0.016	0.983
T68 Hypothermia	0.016	0.983
T66 Unspecified effects of radiation	0.016	0.983
O23 Infections of genito-urinary tract in pregnancy	0.017	0.983
T51 Toxic effect of alcohol	0.016	0.983
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.016	0.983
T93.2 Sequelae of other fractures of lower limb	0.016	0.983
S20 Superficial injury of thorax	0.016	0.983
O69.1 Labour and delivery complicated by cord around neck, with compression	0.016	0.984
O48 Prolonged pregnancy	0.016	0.984
S92 Fracture of foot, except ankle	0.016	0.984
T90 Sequelae of injuries of head	0.016	0.984
O32.1 Maternal care for breech presentation	0.016	0.984
O08 Complications following abortion and ectopic and molar pregnancy	0.016	0.984
O07 Failed attempted abortion	0.016	0.984
O06 Unspecified abortion	0.016	0.984
O05 Other abortion	0.016	0.984
O01 Hydatidiform mole	0.016	0.984
S17 Crushing injury of neck	0.016	0.984
S15 Injury of blood vessels at neck level	0.016	0.984
S14 Injury of nerves and spinal cord at neck level	0.016	0.984
S11 Open wound of neck	0.016	0.984
S18 Traumatic amputation at neck level	0.016	0.984
S16 Injury of muscle and tendon at neck level	0.016	0.984
O82 Single delivery by Caesarean section	0.016	0.984
T98 Sequelae of other and unspecified effects of external causes	0.016	0.984
T95 Sequelae of burns, corrosions and frostbite	0.016	0.984
T91 Sequelae of injuries of neck and trunk	0.016	0.984
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.016	0.984
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.016	0.984
O14.9 Preeclampsia, unspecified	0.016	0.984
T78.4 Allergy, unspecified	0.016	0.984
T70.3 Caisson disease [decompression sickness]	0.016	0.984
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.016	0.984
S26 Injury of heart	0.016	0.984
S25 Injury of blood vessels of thorax	0.016	0.984
S24 Injury of nerves and spinal cord at thorax level	0.016	0.984
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.016	0.984
S21 Open wound of thorax	0.016	0.984
T93.8 Sequelae of other specified injuries of lower limb	0.016	0.984
S89 Other and unspecified injuries of lower leg	0.016	0.984
O69.9 Labour and delivery complicated by cord complication, unspecified	0.015	0.984
O69.8 Labour and delivery complicated by other cord complications	0.015	0.984
O69.5 Labour and delivery complicated by vascular lesion of cord	0.015	0.984
O69.4 Labour and delivery complicated by vasa praevia	0.015	0.984
O69.3 Labour and delivery complicated by short cord	0.015	0.984
O69.0 Labour and delivery complicated by prolapse of cord	0.015	0.984
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.015	0.984
T86 Failure and rejection of transplanted organs and tissues	0.016	0.984
S22.30 Fracture of rib (closed)	0.015	0.984
O46.8 Other antepartum haemorrhage	0.015	0.985
O46.0 Antepartum haemorrhage with coagulation defect	0.015	0.985
O00.1 Tubal pregnancy	0.015	0.985
T78.1 Other adverse food reactions, not elsewhere classified	0.015	0.985
O04.4 Incomplete, without complication	0.015	0.985
S22.4 Multiple fractures of ribs	0.015	0.985
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.015	0.985
T38.9 Other and unspecified hormone antagonists	0.015	0.985
T38.8 Other and unspecified hormones and their synthetic substitutes	0.015	0.985
T38.7 Androgens and anabolic congeners	0.015	0.985
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.015	0.985
T38.5 Other oestrogens and progestogens	0.015	0.985
T38.4 Oral contraceptives	0.015	0.985
T38.2 Antithyroid drugs	0.015	0.985
T38.1 Thyroid hormones and substitutes	0.015	0.985
T38.0 Glucocorticoids and synthetic analogues	0.015	0.985
S29 Other and unspecified injuries of thorax	0.015	0.985
T92 Sequelae of injuries of upper limb	0.015	0.985
O29 Complications of anaesthesia during pregnancy	0.015	0.985
O28 Abnormal findings on antenatal screening of mother	0.015	0.985
O24 Diabetes mellitus in pregnancy	0.015	0.985
O22 Venous complications in pregnancy	0.015	0.985
O21 Excessive vomiting in pregnancy	0.015	0.985
O25 Malnutrition in pregnancy	0.015	0.985
O20.9 Haemorrhage in early pregnancy, unspecified	0.015	0.985
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.015	0.985
S37 Injury of urinary and pelvic organs	0.015	0.985
S36 Injury of intra-abdominal organs	0.015	0.985
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.015	0.985
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.015	0.985
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.015	0.985
S31 Open wound of abdomen, lower back and pelvis	0.015	0.985
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.015	0.985
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.015	0.985
S27 Injury of other and unspecified intrathoracic organs	0.015	0.985
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.015	0.985
T36.9 Systemic antibiotic, unspecified	0.015	0.985
T36.8 Other systemic antibiotics	0.015	0.985
T36.7 Antifungal antibiotics, systemically used	0.015	0.985
T36.6 Rifamycins	0.015	0.985
T36.5 Aminoglycosides	0.015	0.985
T36.4 Tetracyclines	0.015	0.985
T36.3 Macrolides	0.015	0.985
T36.2 Chloramphenicol group	0.015	0.985
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.015	0.985
T36.0 Penicillins	0.015	0.985
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.015	0.985
T37.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.985
T37.5 Antiviral drugs	0.015	0.985
T37.4 Anthelminthics	0.015	0.985
T37.3 Other antiprotozoal drugs	0.015	0.985
T37.2 Antimalarials and drugs acting on other blood protozoa	0.015	0.985
T37.1 Antimycobacterial drugs	0.015	0.985
T37.0 Sulphonamides	0.015	0.985
T41.5 Therapeutic gases	0.015	0.985
T41.4 Anaesthetic, unspecified	0.015	0.985
T41.3 Local anaesthetics	0.015	0.985
T41.2 Other and unspecified general anaesthetics	0.015	0.985
T41.1 Intravenous anaesthetics	0.015	0.985
T41.0 Inhaled anaesthetics	0.015	0.985
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.015	0.985
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.015	0.985
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.015	0.985
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.015	0.985
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.015	0.985
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.015	0.985
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.015	0.985
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.015	0.985
T44.1 Other parasympathomimetics [cholinergics]	0.015	0.985
T44.0 Anticholinesterase agents	0.015	0.985
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.015	0.985
T46.8 Antivaricose drugs, including sclerosing agents	0.015	0.985
T46.7 Peripheral vasodilators	0.015	0.985
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.015	0.985
T46.5 Other antihypertensive drugs, not elsewhere classified	0.015	0.985
T46.4 Angiotensin-converting-enzyme inhibitors	0.015	0.985
T46.3 Coronary vasodilators, not elsewhere classified	0.015	0.985
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.015	0.985
T46.1 Calcium-channel blockers	0.015	0.985
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.015	0.985
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.015	0.985
T47.8 Other agents primarily affecting the gastro-intestinal system	0.015	0.985
T47.7 Emetics	0.015	0.985
T47.6 Antidiarrhoeal drugs	0.015	0.985
T47.5 Digestants	0.015	0.985
T47.4 Other laxatives	0.015	0.985
T47.3 Saline and osmotic laxatives	0.015	0.985
T47.2 Stimulant laxatives	0.015	0.985
T47.1 Other antacids and anti-gastric-secretion drugs	0.015	0.985
T47.0 Histamine H(2)-receptor antagonists	0.015	0.985
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.015	0.985
T48.6 Antiasthmatics, not elsewhere classified	0.015	0.985
T48.5 Anti-common-cold drugs	0.015	0.985
T48.4 Expectorants	0.015	0.985
T48.3 Antitussives	0.015	0.985
T48.2 Other and unspecified agents primarily acting on muscles	0.015	0.985
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.015	0.985
T48.0 Oxytocic drugs	0.015	0.985
T49.9 Topical agent, unspecified	0.015	0.985
T49.8 Other topical agents	0.015	0.985
T49.7 Dental drugs, topically applied	0.015	0.985
T49.6 Otorhinolaryngological drugs and preparations	0.015	0.985
T49.5 Ophthalmological drugs and preparations	0.015	0.985
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.015	0.985
T49.3 Emollients, demulcents and protectants	0.015	0.985
T49.2 Local astringents and local detergents	0.015	0.985
T49.1 Antipruritics	0.015	0.985
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.015	0.985
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.015	0.985
S19.9 Unspecified injury of neck	0.015	0.985
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.015	0.985
O34 Maternal care for known or suspected abnormality of pelvic organs	0.015	0.985
S71 Open wound of hip and thigh	0.015	0.985
O92 Other disorders of breast and lactation associated with childbirth	0.015	0.985
O91 Infections of breast associated with childbirth	0.015	0.985
O90 Complications of the puerperium, not elsewhere classified	0.015	0.985
O89 Complications of anaesthesia during the puerperium	0.015	0.985
O88 Obstetric embolism	0.015	0.985
O87 Venous complications in the puerperium	0.015	0.985
O86 Other puerperal infections	0.015	0.985
O85 Puerperal sepsis	0.015	0.985
T78.9 Adverse effect, unspecified	0.015	0.985
T78.8 Other adverse effects, not elsewhere classified	0.015	0.985
T85 Complications of other internal prosthetic devices, implants and grafts	0.015	0.985
O14.2 HELLP syndrome	0.015	0.985
O14.1 Severe preeclampsia	0.015	0.985
O14.0 Moderate preeclampsia	0.015	0.985
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.015	0.985
O03 Spontaneous abortion	0.015	0.985
O32.9 Maternal care for malpresentation of foetus, unspecified	0.014	0.985
O32.8 Maternal care for other malpresentation of foetus	0.014	0.985
O32.6 Maternal care for compound presentation	0.014	0.985
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.014	0.985
O32.4 Maternal care for high head at term	0.014	0.985
O32.3 Maternal care for face, brow and chin presentation	0.014	0.985
O32.2 Maternal care for transverse and oblique lie	0.014	0.985
O32.0 Maternal care for unstable lie	0.014	0.985
O84 Multiple delivery	0.014	0.985
O83 Other assisted single delivery	0.014	0.985
O81 Single delivery by forceps and vacuum extractor	0.014	0.985
S32 Fracture of lumbar spine and pelvis	0.014	0.985
S99 Other and unspecified injuries of ankle and foot	0.014	0.985
S98 Traumatic amputation of ankle and foot	0.014	0.985
S97 Crushing injury of ankle and foot	0.014	0.985
S96 Injury of muscle and tendon at ankle and foot level	0.014	0.985
S95 Injury of blood vessels at ankle and foot level	0.014	0.985
S94 Injury of nerves at ankle and foot level	0.014	0.985
S90 Superficial injury of ankle and foot	0.014	0.985
T65 Toxic effect of other and unspecified substances	0.014	0.985
T62 Toxic effect of other noxious substances eaten as food	0.014	0.985
T61 Toxic effect of noxious substances eaten as seafood	0.014	0.985
T60 Toxic effect of pesticides	0.014	0.985
T59 Toxic effect of other gases, fumes and vapours	0.014	0.985
T57 Toxic effect of other inorganic substances	0.014	0.985
T56 Toxic effect of metals	0.014	0.985
T54 Toxic effect of corrosive substances	0.014	0.985
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.014	0.985
T52 Toxic effect of organic solvents	0.014	0.985
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.014	0.985
T58 Toxic effect of carbon monoxide	0.014	0.985
T55 Toxic effect of soaps and detergents	0.014	0.985
O41.0 Oligohydramnios	0.014	0.985
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.014	0.985
S30.0 Contusion of lower back and pelvis	0.014	0.985
T78.2 Anaphylactic shock, unspecified	0.014	0.986
T40.4 Other synthetic narcotics	0.014	0.986
T63 Toxic effect of contact with venomous animals	0.014	0.986
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.014	0.986
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.986
T42.5 Mixed antiepileptics, not elsewhere classified	0.014	0.986
T42.4 Benzodiazepines	0.014	0.986
T42.3 Barbiturates	0.014	0.986
T42.2 Succinimides and oxazolidinediones	0.014	0.986
T42.1 Iminostilbenes	0.014	0.986
T42.0 Hydantoin derivatives	0.014	0.986
S81 Open wound of lower leg	0.014	0.986
S12.2 Fracture of other specified cervical vertebra	0.014	0.986
S91 Open wound of ankle and foot	0.014	0.986
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.014	0.986
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.014	0.986
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.014	0.986
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.014	0.986
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.014	0.986
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.014	0.986
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.014	0.986
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.014	0.986
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.014	0.986
T51.0 Ethanol	0.014	0.986
S78 Traumatic amputation of hip and thigh	0.014	0.986
S77 Crushing injury of hip and thigh	0.014	0.986
S76 Injury of muscle and tendon at hip and thigh level	0.014	0.986
S75 Injury of blood vessels at hip and thigh level	0.014	0.986
S74 Injury of nerves at hip and thigh level	0.014	0.986
S86 Injury of muscle and tendon at lower leg level	0.014	0.986
S70 Superficial injury of hip and thigh	0.014	0.986
O04.9 Complete or unspecified, without complication	0.014	0.986
S22.9 Fracture of bony thorax, part unspecified	0.014	0.986
S22.8 Fracture of other parts of bony thorax	0.014	0.986
S22.5 Flail chest	0.014	0.986
S22.2 Fracture of sternum	0.014	0.986
S22.1 Multiple fractures of thoracic spine	0.014	0.986
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.014	0.986
O41.8 Other specified disorders of amniotic fluid and membranes	0.014	0.986
O41.1 Infection of amniotic sac and membranes	0.014	0.986
O44.1 Placenta praevia with haemorrhage	0.014	0.986
S72 Fracture of femur	0.014	0.986
T93.9 Sequelae of unspecified injury of lower limb	0.014	0.986
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.014	0.986
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.014	0.986
T93.4 Sequelae of injury of nerve of lower limb	0.014	0.986
T93.1 Sequelae of fracture of femur	0.014	0.986
T93.0 Sequelae of open wound of lower limb	0.014	0.986
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.014	0.986
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.014	0.986

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations