TreeWAS – Variant ID: rs78315000

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.115	0.885	0.000
H66 Suppurative and unspecified otitis media	0.112	0.888	0.000
H72 Perforation of tympanic membrane	0.111	0.889	0.000
H71 Cholesteatoma of middle ear	0.110	0.890	0.000
H66.9 Otitis media, unspecified	0.109	0.891	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.103	0.897	0.000
H65 Nonsuppurative otitis media	0.096	0.904	0.000
H72.0 Central perforation of tympanic membrane	0.096	0.904	0.000
H66.3 Other chronic suppurative otitis media	0.091	0.909	0.000
H74 Other disorders of middle ear and mastoid	0.085	0.915	0.000
H72.8 Other perforations of tympanic membrane	0.084	0.916	0.000
H65.3 Chronic mucoid otitis media	0.083	0.917	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.082	0.917	0.000
H68 Eustachian salpingitis and obstruction	0.082	0.917	0.000
H67 Otitis media in diseases classified elsewhere	0.082	0.917	0.000
H65.2 Chronic serous otitis media	0.082	0.918	0.000
H66.4 Suppurative otitis media, unspecified	0.081	0.919	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.081	0.919	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.081	0.919	0.000
H66.0 Acute suppurative otitis media	0.081	0.919	0.000
H70 Mastoiditis and related conditions	0.080	0.920	0.000
H72.2 Other marginal perforations of tympanic membrane	0.080	0.920	0.000
H72.1 Attic perforation of tympanic membrane	0.080	0.920	0.000
H69 Other disorders of Eustachian tube	0.077	0.923	0.000
H73 Other disorders of tympanic membrane	0.071	0.929	0.000
Chapter VIII Diseases of the ear and mastoid process	0.070	0.930	0.000
H65.1 Other acute nonsuppurative otitis media	0.069	0.931	0.000
H65.0 Acute serous otitis media	0.069	0.931	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.069	0.931	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.063	0.937	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.061	0.939	0.000
H74.1 Adhesive middle ear disease	0.061	0.939	0.000
H74.0 Tympanosclerosis	0.061	0.939	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.061	0.939	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.059	0.941	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.059	0.941	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.059	0.941	0.000
H68.1 Obstruction of Eustachian tube	0.059	0.941	0.000
H68.0 Eustachian salpingitis	0.059	0.941	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.059	0.941	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.059	0.941	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.059	0.941	0.000
H60-H62 Diseases of external ear	0.059	0.941	0.000
H70.8 Other mastoiditis and related conditions	0.058	0.942	0.000
H70.2 Petrositis	0.058	0.942	0.000
H70.1 Chronic mastoiditis	0.058	0.942	0.000
H70.0 Acute mastoiditis	0.058	0.942	0.000
H65.4 Other chronic nonsuppurative otitis media	0.057	0.943	0.000
H70.9 Mastoiditis, unspecified	0.055	0.944	0.000
H69.8 Other specified disorders of Eustachian tube	0.055	0.945	0.000
H69.0 Patulous Eustachian tube	0.055	0.945	0.000
H74.4 Polyp of middle ear	0.054	0.946	0.000
R94.5 Abnormal results of liver function studies	0.000	0.946	0.054
H80-H83 Diseases of inner ear	0.053	0.947	0.000
H90-H95 Other disorders of ear	0.053	0.947	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.051	0.949	0.000
H73.1 Chronic myringitis	0.051	0.949	0.000
H73.0 Acute myringitis	0.051	0.949	0.000
H61 Other disorders of external ear	0.050	0.950	0.000
H69.9 Eustachian tube disorder, unspecified	0.049	0.951	0.000
H61.2 Impacted cerumen	0.047	0.953	0.000
H92 Otalgia and effusion of ear	0.047	0.953	0.000
H80 Otosclerosis	0.046	0.954	0.000
H92.1 Otorrhoea	0.045	0.955	0.000
H60 Otitis externa	0.044	0.956	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.042	0.957	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.042	0.958	0.000
H80.9 Otosclerosis, unspecified	0.041	0.959	0.000
H73.8 Other specified disorders of tympanic membrane	0.039	0.961	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.038	0.962	0.000
H60.1 Cellulitis of external ear	0.038	0.962	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.038	0.962	0.000
H81 Disorders of vestibular function	0.037	0.963	0.000
H90 Conductive and sensorineural hearing loss	0.036	0.964	0.000
H61.3 Acquired stenosis of external ear canal	0.036	0.964	0.000
H61.1 Non-infective disorders of pinna	0.036	0.964	0.000
H61.9 Disorder of external ear, unspecified	0.035	0.965	0.000
H61.8 Other specified disorders of external ear	0.035	0.965	0.000
H92.2 Otorrhagia	0.034	0.966	0.000
H95.1 Other disorders following mastoidectomy	0.034	0.966	0.000
H80.8 Other otosclerosis	0.033	0.967	0.000
H80.2 Cochlear otosclerosis	0.033	0.967	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.033	0.967	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.033	0.967	0.000
H93 Other disorders of ear, not elsewhere classified	0.033	0.967	0.000
H60.8 Other otitis externa	0.032	0.968	0.000
H60.5 Acute otitis externa, non-infective	0.032	0.968	0.000
H60.4 Cholesteatoma of external ear	0.032	0.968	0.000
H60.3 Other infective otitis externa	0.032	0.968	0.000
H60.2 Malignant otitis externa	0.032	0.968	0.000
H60.0 Abscess of external ear	0.032	0.968	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.030	0.969	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.030	0.969	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.030	0.969	0.000
H62.2 Otitis externa in mycoses	0.030	0.969	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.030	0.969	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.030	0.969	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.030	0.970	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.030	0.970	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.030	0.970	0.000
H83 Other diseases of inner ear	0.029	0.970	0.000
H92.0 Otalgia	0.029	0.970	0.000
H81.0 Meniere's disease	0.028	0.972	0.000
H90.3 Sensorineural hearing loss, bilateral	0.028	0.972	0.000
H81.1 Benign paroxysmal vertigo	0.027	0.972	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.027	0.972	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.027	0.972	0.000
H90.2 Conductive hearing loss, unspecified	0.027	0.973	0.000
H81.9 Disorder of vestibular function, unspecified	0.027	0.973	0.000
H81.8 Other disorders of vestibular function	0.027	0.973	0.000
H81.4 Vertigo of central origin	0.027	0.973	0.000
H81.3 Other peripheral vertigo	0.027	0.973	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.026	0.974	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.026	0.974	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.026	0.974	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.026	0.974	0.000
H93.8 Other specified disorders of ear	0.026	0.974	0.000
H90.0 Conductive hearing loss, bilateral	0.025	0.975	0.000
H60.9 Otitis externa, unspecified	0.025	0.975	0.000
H90.5 Sensorineural hearing loss, unspecified	0.025	0.975	0.000
H81.2 Vestibular neuronitis	0.024	0.976	0.000
H93.9 Disorder of ear, unspecified	0.023	0.976	0.000
H93.3 Disorders of acoustic nerve	0.023	0.976	0.000
H93.2 Other abnormal auditory perceptions	0.023	0.976	0.000
H93.0 Degenerative and vascular disorders of ear	0.023	0.976	0.000
H91 Other hearing loss	0.024	0.976	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.022	0.977	0.000
H83.9 Disease of inner ear, unspecified	0.021	0.978	0.000
H83.8 Other specified diseases of inner ear	0.021	0.978	0.000
H83.3 Noise effects on inner ear	0.021	0.978	0.000
H83.2 Labyrinthine dysfunction	0.021	0.978	0.000
H83.1 Labyrinthine fistula	0.021	0.978	0.000
H61.0 Perichondritis of external ear	0.020	0.979	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.017	0.983	0.000
H91.3 Deaf mutism, not elsewhere classified	0.017	0.983	0.000
H91.2 Sudden idiopathic hearing loss	0.017	0.983	0.000
H91.1 Presbycusis	0.017	0.983	0.000
H91.0 Ototoxic hearing loss	0.017	0.983	0.000
H91.8 Other specified hearing loss	0.016	0.984	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.016	0.984	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.014	0.986	0.000
H93.1 Tinnitus	0.013	0.986	0.000
S60-S69 Injuries to the wrist and hand	0.014	0.986	0.000
R94 Abnormal results of function studies	0.000	0.986	0.014
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.013	0.987	0.000
H83.0 Labyrinthitis	0.012	0.987	0.000
S64 Injury of nerves at wrist and hand level	0.012	0.988	0.000
S61 Open wound of wrist and hand	0.012	0.988	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.012	0.988	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.012	0.988	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.012	0.988	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.012	0.988	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.012	0.988	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.012	0.988	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.011	0.989	0.000
S64.3 Injury of digital nerve of thumb	0.011	0.989	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.011	0.989	0.000
I20.0 Unstable angina	0.011	0.989	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.011	0.989	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.011	0.989	0.000
S61.8 Open wound of other parts of wrist and hand	0.011	0.989	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.010	0.989	0.000
S65 Injury of blood vessels at wrist and hand level	0.010	0.990	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.000	0.990	0.010
R94.7 Abnormal results of other endocrine function studies	0.000	0.990	0.010
R94.6 Abnormal results of thyroid function studies	0.000	0.990	0.010
R94.2 Abnormal results of pulmonary function studies	0.000	0.990	0.010
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.000	0.990	0.010
R94.0 Abnormal results of function studies of central nervous system	0.000	0.990	0.010
T66-T78 Other and unspecified effects of external causes	0.010	0.990	0.000
S64.4 Injury of digital nerve of other finger	0.010	0.990	0.000
S69 Other and unspecified injuries of wrist and hand	0.010	0.990	0.000
S60 Superficial injury of wrist and hand	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.009	0.990	0.000
T78 Adverse effects, not elsewhere classified	0.009	0.991	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.009	0.991	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
S68 Traumatic amputation of wrist and hand	0.009	0.991	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.009	0.991	0.000
S90-S99 Injuries to the ankle and foot	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
S61.7 Multiple open wounds of wrist and hand	0.009	0.991	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.009	0.991	0.000
S64.8 Injury of other nerves at wrist and hand level	0.009	0.991	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.009	0.991	0.000
S64.1 Injury of median nerve at wrist and hand level	0.009	0.991	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.009	0.991	0.000
T43.2 Other and unspecified antidepressants	0.009	0.991	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.009	0.991	0.000
S67 Crushing injury of wrist and hand	0.009	0.991	0.000
S10-S19 Injuries to the neck	0.009	0.991	0.000
R94.4 Abnormal results of kidney function studies	0.000	0.991	0.009
S63.5 Sprain and strain of wrist	0.009	0.991	0.000
T78.4 Allergy, unspecified	0.009	0.991	0.000
T92 Sequelae of injuries of upper limb	0.009	0.991	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.009	0.991	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.009	0.991	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.009	0.991	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.009	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.008	0.991	0.000
S61.0 Open wound of finger(s) without damage to nail	0.008	0.992	0.000
T00-T07 Injuries involving multiple body regions	0.008	0.992	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.008	0.992	0.000
S63.1 Dislocation finger	0.008	0.992	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.008	0.992	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.008	0.992	0.000
S63.2 Multiple dislocations of fingers	0.008	0.992	0.000
S63.0 Dislocation of wrist	0.008	0.992	0.000
S20-S29 Injuries to the thorax	0.008	0.992	0.000
T79-T79 Certain early complications of trauma	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
T33-T35 Frostbite	0.008	0.992	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.008	0.992	0.000
S92 Fracture of foot, except ankle	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.992	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
T36 Poisoning by systemic antibiotics	0.008	0.992	0.000
T42.4 Benzodiazepines	0.008	0.992	0.000
T93 Sequelae of injuries of lower limb	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
S12 Fracture of neck	0.008	0.992	0.000
S91 Open wound of ankle and foot	0.008	0.992	0.000
S60.2 Contusion of other parts of wrist and hand	0.007	0.992	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.007	0.992	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.007	0.992	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.007	0.992	0.000
S65.5 Injury of blood vessel(s) of other finger	0.007	0.992	0.000
S65.4 Injury of blood vessel(s) of thumb	0.007	0.992	0.000
S65.3 Injury of deep palmar arch	0.007	0.992	0.000
S65.2 Injury of superficial palmar arch	0.007	0.992	0.000
S65.1 Injury of radial artery at wrist and hand level	0.007	0.992	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.007	0.992	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.007	0.992	0.000
T93.2 Sequelae of other fractures of lower limb	0.007	0.992	0.000
S70-S79 Injuries to the hip and thigh	0.007	0.992	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.007	0.993	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.993	0.007
T75 Effects of other external causes	0.007	0.993	0.000
T74 Maltreatment syndromes	0.007	0.993	0.000
T73 Effects of other deprivation	0.007	0.993	0.000
T70 Effects of air pressure and water pressure	0.007	0.993	0.000
T69 Other effects of reduced temperature	0.007	0.993	0.000
T67 Effects of heat and light	0.007	0.993	0.000
T71 Asphyxiation	0.007	0.993	0.000
T66 Unspecified effects of radiation	0.007	0.993	0.000
T78.3 Angioneurotic oedema	0.007	0.993	0.000
T17 Foreign body in respiratory tract	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.007	0.993	0.000
S69.8 Other specified injuries of wrist and hand	0.007	0.993	0.000
S69.7 Multiple injuries of wrist and hand	0.007	0.993	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.007	0.993	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.007	0.993	0.000
S60.1 Contusion of finger(s) with damage to nail	0.007	0.993	0.000
S60.0 Contusion of finger(s) without damage to nail	0.007	0.993	0.000
S61.1 Open wound of finger(s) with damage to nail	0.007	0.993	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.007	0.993	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.007	0.993	0.000
T78.9 Adverse effect, unspecified	0.007	0.993	0.000
T78.8 Other adverse effects, not elsewhere classified	0.007	0.993	0.000
T98 Sequelae of other and unspecified effects of external causes	0.007	0.993	0.000
T95 Sequelae of burns, corrosions and frostbite	0.007	0.993	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.007	0.993	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.007	0.993	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
T92.1 Sequelae of fracture of arm	0.007	0.993	0.000
T50.8 Diagnostic agents	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.4 Drugs affecting uric acid metabolism	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
T78.2 Anaphylactic shock, unspecified	0.007	0.993	0.000
T13 Other injuries of lower limb, level unspecified	0.007	0.993	0.000
S63.6 Sprain and strain of finger(s)	0.007	0.993	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.007	0.993	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.007	0.993	0.000
S68.4 Traumatic amputation of hand at wrist level	0.007	0.993	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.007	0.993	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.007	0.993	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.007	0.993	0.000
M54.9 Dorsalgia, unspecified	0.007	0.993	0.000
S99 Other and unspecified injuries of ankle and foot	0.007	0.993	0.000
S98 Traumatic amputation of ankle and foot	0.007	0.993	0.000
S97 Crushing injury of ankle and foot	0.007	0.993	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.007	0.993	0.000
S95 Injury of blood vessels at ankle and foot level	0.007	0.993	0.000
S94 Injury of nerves at ankle and foot level	0.007	0.993	0.000
S90 Superficial injury of ankle and foot	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
T46.1 Calcium-channel blockers	0.007	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
T11 Other injuries of upper limb, level unspecified	0.007	0.993	0.000
S50-S59 Injuries to the elbow and forearm	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.007	0.993	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.007	0.993	0.000
T68 Hypothermia	0.007	0.993	0.000
S12.2 Fracture of other specified cervical vertebra	0.007	0.993	0.000
S60.8 Other superficial injuries of wrist and hand	0.007	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
T42.1 Iminostilbenes	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.007	0.993	0.000
T51 Toxic effect of alcohol	0.007	0.993	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.007	0.993	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.006	0.993	0.000
S17 Crushing injury of neck	0.007	0.993	0.000
S15 Injury of blood vessels at neck level	0.007	0.993	0.000
S14 Injury of nerves and spinal cord at neck level	0.007	0.993	0.000
S11 Open wound of neck	0.007	0.993	0.000
S10 Superficial injury of neck	0.007	0.993	0.000
S18 Traumatic amputation at neck level	0.007	0.993	0.000
S16 Injury of muscle and tendon at neck level	0.007	0.993	0.000
T59 Toxic effect of other gases, fumes and vapours	0.007	0.993	0.000
S92.3 Fracture of metatarsal bone	0.007	0.993	0.000
S80-S89 Injuries to the knee and lower leg	0.007	0.993	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.007	0.993	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.007	0.993	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.007	0.993	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.007	0.993	0.000
S69.9 Unspecified injury of wrist and hand	0.006	0.993	0.000
T02 Fractures involving multiple body regions	0.006	0.993	0.000
S92.5 Fracture of other toe	0.006	0.993	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.007	0.993	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.993	0.000
T19 Foreign body in genito-urinary tract	0.006	0.993	0.000
T15 Foreign body on external eye	0.006	0.993	0.000
T16 Foreign body in ear	0.006	0.993	0.000
T09 Other injuries of spine and trunk, level unspecified	0.006	0.993	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.006	0.993	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.006	0.993	0.000
T12 Fracture of lower limb, level unspecified	0.006	0.993	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.006	0.993	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.006	0.993	0.000
T10 Fracture of upper limb, level unspecified	0.006	0.993	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.006	0.993	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.006	0.993	0.000
T08 Fracture of spine, level unspecified	0.006	0.993	0.000
T23 Burn and corrosion of wrist and hand	0.006	0.993	0.000
S62 Fracture at wrist and hand level	0.006	0.994	0.001
S71 Open wound of hip and thigh	0.006	0.994	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.006	0.994	0.000
T91 Sequelae of injuries of neck and trunk	0.006	0.994	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
T65 Toxic effect of other and unspecified substances	0.006	0.994	0.000
T62 Toxic effect of other noxious substances eaten as food	0.006	0.994	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.006	0.994	0.000
T60 Toxic effect of pesticides	0.006	0.994	0.000
T57 Toxic effect of other inorganic substances	0.006	0.994	0.000
T56 Toxic effect of metals	0.006	0.994	0.000
T54 Toxic effect of corrosive substances	0.006	0.994	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.006	0.994	0.000
T52 Toxic effect of organic solvents	0.006	0.994	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.006	0.994	0.000
T58 Toxic effect of carbon monoxide	0.006	0.994	0.000
T55 Toxic effect of soaps and detergents	0.006	0.994	0.000
S29 Other and unspecified injuries of thorax	0.006	0.994	0.000
S37 Injury of urinary and pelvic organs	0.006	0.994	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.006	0.994	0.000
S56 Injury of muscle and tendon at forearm level	0.006	0.994	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.006	0.994	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.006	0.994	0.000
T05 Traumatic amputations involving multiple body regions	0.006	0.994	0.000
T04 Crushing injuries involving multiple body regions	0.006	0.994	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.006	0.994	0.000
T01 Open wounds involving multiple body regions	0.006	0.994	0.000
T00 Superficial injuries involving multiple body regions	0.006	0.994	0.000
T07 Unspecified multiple injuries	0.006	0.994	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.006	0.994	0.000
T18 Foreign body in alimentary tract	0.006	0.994	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.006	0.994	0.000
S91.1 Open wound of toe(s) without damage to nail	0.006	0.994	0.000
T25 Burn and corrosion of ankle and foot	0.006	0.994	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T21 Burn and corrosion of trunk	0.006	0.994	0.000
T20 Burn and corrosion of head and neck	0.006	0.994	0.000
S40-S49 Injuries to the shoulder and upper arm	0.006	0.994	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.006	0.994	0.000
S91.3 Open wound of other parts of foot	0.006	0.994	0.000
S19 Other and unspecified injuries of neck	0.006	0.994	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.006	0.994	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
S92.4 Fracture of great toe	0.006	0.994	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.006	0.994	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.006	0.994	0.000
T92.0 Sequelae of open wound of upper limb	0.006	0.994	0.000
S27 Injury of other and unspecified intrathoracic organs	0.006	0.994	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.006	0.994	0.000
S26 Injury of heart	0.006	0.994	0.000
S25 Injury of blood vessels of thorax	0.006	0.994	0.000
S24 Injury of nerves and spinal cord at thorax level	0.006	0.994	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.006	0.994	0.000
S21 Open wound of thorax	0.006	0.994	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.006	0.994	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
T14 Injury of unspecified body region	0.006	0.994	0.000
T28 Burn and corrosion of other internal organs	0.006	0.994	0.000
T27 Burn and corrosion of respiratory tract	0.006	0.994	0.000
T26 Burn and corrosion confined to eye and adnexa	0.006	0.994	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.006	0.994	0.000
T34 Frostbite with tissue necrosis	0.006	0.994	0.000
T33 Superficial frostbite	0.006	0.994	0.000
T63 Toxic effect of contact with venomous animals	0.006	0.994	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
S92.9 Fracture of foot, unspecified	0.006	0.994	0.000
S92.7 Multiple fractures of foot	0.006	0.994	0.000
S92.2 Fracture of other tarsal bone(s)	0.006	0.994	0.000
S92.1 Fracture of talus	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.4 Other laxatives	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.994	0.006
T17.9 Foreign body in respiratory tract, part unspecified	0.006	0.994	0.000
S12.7 Multiple fractures of cervical spine	0.006	0.994	0.000
S20 Superficial injury of thorax	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations