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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78538083
log Bayes Factor = <0.0001
Chromosome 4   position 123,568,409  (GRCh37) Explore rs78538083 on Ensembl!
Variant rs78538083 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M25.51 Pain in joint (Shoulder region)
0.022 0.978 0.000
M25 Other joint disorders, not elsewhere classified
0.021 0.979 0.000
M25.5 Pain in joint
0.021 0.979 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.020 0.980 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.019 0.981 0.000
M25.4 Effusion of joint
0.019 0.981 0.000
M25.54 Pain in joint (Hand)
0.019 0.981 0.000
M25.9 Joint disorder, unspecified
0.018 0.982 0.000
M25.53 Pain in joint (Forearm)
0.018 0.982 0.000
M20-M25 Other joint disorders
0.017 0.983 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.017 0.983 0.000
M25.57 Pain in joint (Ankle and foot)
0.016 0.984 0.000
M25.52 Pain in joint (Upper arm)
0.016 0.984 0.000
M22.4 Chondromalacia patellae
0.016 0.984 0.000
D68.5 Primary Thrombophilia
0.016 0.984 0.000
M22 Disorders of patella
0.016 0.984 0.000
D68 Other coagulation defects
0.016 0.984 0.000
M25.59 Pain in joint (Site unspecified)
0.016 0.984 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.016 0.984 0.000
M25.2 Flail joint
0.015 0.985 0.000
M25.1 Fistula of joint
0.015 0.985 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.015 0.985 0.000
M25.58 Pain in joint (Other)
0.015 0.985 0.000
M24 Other specific joint derangements
0.015 0.985 0.000
M81.9 Osteoporosis, unspecified
0.015 0.985 0.000
M80-M85 Disorders of bone density and structure
0.015 0.985 0.000
M25.43 Effusion of joint (Forearm)
0.015 0.985 0.000
M25.42 Effusion of joint (Upper arm)
0.015 0.985 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.015 0.985 0.000
M25.47 Effusion of joint (Ankle and foot)
0.015 0.985 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.015 0.985 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.014 0.985 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.014 0.985 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.014 0.985 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.014 0.985 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.014 0.985 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.014 0.985 0.000
C62.9 Testis, unspecified
0.015 0.985 0.000
M81 Osteoporosis without pathological fracture
0.014 0.985 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.014 0.986 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.014 0.986 0.000
M85 Other disorders of bone density and structure
0.014 0.986 0.000
M25.0 Haemarthrosis
0.014 0.986 0.000
D69 Purpura and other haemorrhagic conditions
0.014 0.986 0.000
M81.98 Osteoporosis, unspecified (Other)
0.014 0.986 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.014 0.986 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.014 0.986 0.000
M85.8 Other specified disorders of bone density and structure
0.014 0.986 0.000
M86-M90 Other osteopathies
0.014 0.986 0.000
M25.49 Effusion of joint (Site unspecified)
0.014 0.986 0.000
M25.48 Effusion of joint (Other)
0.014 0.986 0.000
M25.44 Effusion of joint (Hand)
0.014 0.986 0.000
M25.41 Effusion of joint (Shoulder region)
0.014 0.986 0.000
M25.40 Effusion of joint (Multiple sites)
0.014 0.986 0.000
M25.46 Effusion of joint (Lower leg)
0.014 0.986 0.000
D68.2 Hereditary deficiency of other clotting factors
0.014 0.986 0.000
D66 Hereditary factor VIII deficiency
0.014 0.986 0.000
M89 Other disorders of bone
0.013 0.986 0.000
D69.6 Thrombocytopenia, unspecified
0.013 0.987 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.013 0.987 0.000
M25.98 Joint disorder, unspecified (Other)
0.013 0.987 0.000
M25.94 Joint disorder, unspecified (Hand)
0.013 0.987 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.013 0.987 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.013 0.987 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.013 0.987 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.013 0.987 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.013 0.987 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.013 0.987 0.000
M34 Systemic sclerosis
0.013 0.987 0.000
M24.5 Contracture of joint
0.013 0.987 0.000
M25.7 Osteophyte
0.013 0.987 0.000
M25.3 Other instability of joint
0.013 0.987 0.000
M25.8 Other specified joint disorders
0.013 0.987 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.013 0.987 0.000
M45-M49 Spondylopathies
0.013 0.987 0.000
M33 Dermatopolymyositis
0.012 0.987 0.000
M48 Other spondylopathies
0.013 0.987 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.012 0.988 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.012 0.988 0.000
M22.3 Other derangements of patella
0.012 0.988 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.012 0.988 0.000
M32 Systemic lupus erythematosus
0.012 0.988 0.000
M48.0 Spinal stenosis
0.012 0.988 0.000
M25.50 Pain in joint (Multiple sites)
0.012 0.988 0.000
G57.6 Lesion of plantar nerve
0.012 0.988 0.000
M89.8 Other specified disorders of bone
0.012 0.988 0.000
M30 Polyarteritis nodosa and related conditions
0.012 0.988 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.012 0.988 0.000
M24.2 Disorder of ligament
0.012 0.988 0.000
M84 Disorders of continuity of bone
0.012 0.988 0.000
M31 Other necrotising vasculopathies
0.012 0.988 0.000
M48.02 Spinal stenosis (Cervical region)
0.012 0.988 0.000
D68.9 Coagulation defect, unspecified
0.012 0.988 0.000
D72 Other disorders of white blood cells
0.012 0.988 0.000
M89.9 Disorder of bone, unspecified
0.012 0.988 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.012 0.988 0.000
M22.1 Recurrent subluxation of patella
0.011 0.988 0.000
M22.9 Disorder of patella, unspecified
0.011 0.988 0.000
M22.0 Recurrent dislocation of patella
0.011 0.988 0.000
M24.7 Protrusio acetabuli
0.012 0.988 0.000
D68.4 Acquired coagulation factor deficiency
0.011 0.988 0.000
D68.1 Hereditary factor XI deficiency
0.011 0.988 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.011 0.988 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.011 0.988 0.000
D67 Hereditary factor IX deficiency
0.011 0.988 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.011 0.988 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.011 0.989 0.000
M87 Osteonecrosis
0.011 0.989 0.000
M25.74 Osteophyte (Hand)
0.011 0.989 0.000
M40-M43 Deforming dorsopathies
0.011 0.989 0.000
M46 Other inflammatory spondylopathies
0.011 0.989 0.000
M25.19 Fistula of joint (Site unspecified)
0.011 0.989 0.000
M25.18 Fistula of joint (Other)
0.011 0.989 0.000
M25.17 Fistula of joint (Ankle and foot)
0.011 0.989 0.000
M25.16 Fistula of joint (Lower leg)
0.011 0.989 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.011 0.989 0.000
M25.14 Fistula of joint (Hand)
0.011 0.989 0.000
M25.13 Fistula of joint (Forearm)
0.011 0.989 0.000
M25.12 Fistula of joint (Upper arm)
0.011 0.989 0.000
M25.11 Fistula of joint (Shoulder region)
0.011 0.989 0.000
M25.10 Fistula of joint (Multiple sites)
0.011 0.989 0.000
M25.29 Flail joint (Site unspecified)
0.011 0.989 0.000
M25.28 Flail joint (Other)
0.011 0.989 0.000
M25.27 Flail joint (Ankle and foot)
0.011 0.989 0.000
M25.26 Flail joint (Lower leg)
0.011 0.989 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.011 0.989 0.000
M25.24 Flail joint (Hand)
0.011 0.989 0.000
M25.23 Flail joint (Forearm)
0.011 0.989 0.000
M25.22 Flail joint (Upper arm)
0.011 0.989 0.000
M25.21 Flail joint (Shoulder region)
0.011 0.989 0.000
M25.20 Flail joint (Multiple sites)
0.011 0.989 0.000
M85.6 Other cyst of bone
0.011 0.989 0.000
M82 Osteoporosis in diseases classified elsewhere
0.011 0.989 0.000
M50-M54 Other dorsopathies
0.011 0.989 0.000
D72.8 Other specified disorders of white blood cells
0.011 0.989 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.011 0.989 0.000
M24.9 Joint derangement, unspecified
0.011 0.989 0.000
M24.6 Ankylosis of joint
0.011 0.989 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.011 0.989 0.000
C62 Malignant neoplasm of testis
0.011 0.989 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.011 0.989 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.011 0.989 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.011 0.989 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.011 0.989 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.011 0.989 0.000
M83 Adult osteomalacia
0.011 0.989 0.000
D69.0 Allergic purpura
0.011 0.989 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.011 0.989 0.000
D69.9 Haemorrhagic condition, unspecified
0.011 0.989 0.000
D73 Diseases of spleen
0.011 0.989 0.000
M89.3 Hypertrophy of bone
0.011 0.989 0.000
D70 Agranulocytosis
0.011 0.989 0.000
D60-D64 Aplastic and other anaemias
0.011 0.989 0.000
M60-M63 Disorders of muscles
0.011 0.989 0.000
M22.2 Patellofemoral disorders
0.011 0.989 0.000
M24.0 Loose body in joint
0.011 0.989 0.000
M24.51 Contracture of joint (Shoulder region)
0.011 0.989 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.011 0.989 0.000
M81.8 Other osteoporosis
0.010 0.989 0.000
M81.6 Localised osteoporosis [Lequesne]
0.010 0.989 0.000
M81.5 Idiopathic osteoporosis
0.010 0.989 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.010 0.989 0.000
M81.2 Osteoporosis of disuse
0.010 0.989 0.000
M81.1 Postoophorectomy osteoporosis
0.010 0.989 0.000
M81.0 Postmenopausal osteoporosis
0.010 0.989 0.000
M23 Internal derangement of knee
0.011 0.989 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.010 0.989 0.000
D69.5 Secondary thrombocytopenia
0.010 0.989 0.000
D62 Acute posthaemorrhagic anaemia
0.011 0.989 0.000
M86 Osteomyelitis
0.010 0.989 0.000
D69.8 Other specified haemorrhagic conditions
0.010 0.989 0.000
D69.4 Other primary thrombocytopenia
0.010 0.989 0.000
D69.2 Other nonthrombocytopenic purpura
0.010 0.989 0.000
D69.1 Qualitative platelet defects
0.010 0.989 0.000
M85.9 Disorder of bone density and structure, unspecified
0.010 0.989 0.000
M85.5 Aneurysmal bone cyst
0.010 0.989 0.000
M85.4 Solitary bone cyst
0.010 0.989 0.000
M85.3 Osteitis condensans
0.010 0.989 0.000
M85.2 Hyperostosis of skull
0.010 0.989 0.000
M85.1 Skeletal fluorosis
0.010 0.989 0.000
M25.09 Haemarthrosis (Site unspecified)
0.010 0.989 0.000
M25.08 Haemarthrosis (Other)
0.010 0.989 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.010 0.989 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.010 0.989 0.000
M25.04 Haemarthrosis (Hand)
0.010 0.989 0.000
M25.03 Haemarthrosis (Forearm)
0.010 0.989 0.000
M25.02 Haemarthrosis (Upper arm)
0.010 0.989 0.000
M25.01 Haemarthrosis (Shoulder region)
0.010 0.989 0.000
M25.00 Haemarthrosis (Multiple sites)
0.010 0.989 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.010 0.990 0.000
M24.54 Contracture of joint (Hand)
0.010 0.990 0.000
D68.6 Other Thrombophilia
0.010 0.990 0.000
D68.0 Von Willebrand's disease
0.010 0.990 0.000
M25.77 Osteophyte (Ankle and foot)
0.010 0.990 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.010 0.990 0.000
M35 Other systemic involvement of connective tissue
0.010 0.990 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.010 0.990 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.010 0.990 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.010 0.990 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.010 0.990 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.010 0.990 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.010 0.990 0.000
M87.2 Osteonecrosis due to previous trauma
0.010 0.990 0.000
D68.8 Other specified coagulation defects
0.010 0.990 0.000
M24.23 Disorder of ligament (Forearm)
0.010 0.990 0.000
M89.88 Other specified disorders of bone (Other)
0.010 0.990 0.000
M34.1 CR(E)ST syndrome
0.010 0.990 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.010 0.990 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.010 0.990 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.010 0.990 0.000
M88 Paget's disease of bone [osteitis deformans]
0.010 0.990 0.000
M91-M94 Chondropathies
0.010 0.990 0.000
M25.36 Other instability of joint (Lower leg)
0.010 0.990 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.010 0.990 0.000
M89.6 Osteopathy after poliomyelitis
0.010 0.990 0.000
M89.5 Osteolysis
0.010 0.990 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.010 0.990 0.000
M89.2 Other disorders of bone development and growth
0.010 0.990 0.000
M89.1 Epiphyseal arrest
0.010 0.990 0.000
M24.1 Other articular cartilage disorders
0.010 0.990 0.000
M85.0 Fibrous dysplasia (monostotic)
0.010 0.990 0.000
M90 Osteopathies in diseases classified elsewhere
0.010 0.990 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.010 0.990 0.000
G57.8 Other mononeuropathies of lower limb
0.010 0.990 0.000
M46.4 Discitis, unspecified
0.010 0.990 0.000
M89.0 Algoneurodystrophy
0.010 0.990 0.000
G57 Mononeuropathies of lower limb
0.010 0.990 0.000
M50 Cervical disk disorders
0.010 0.990 0.000
M40 Kyphosis and lordosis
0.010 0.990 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.010 0.990 0.000
M22.8 Other disorders of patella
0.010 0.990 0.000
M00-M03 Infectious arthropathies
0.010 0.990 0.000
M48.09 Spinal stenosis (Site unspecified)
0.010 0.990 0.000
M25.06 Haemarthrosis (Lower leg)
0.009 0.990 0.000
M25.34 Other instability of joint (Hand)
0.009 0.990 0.000
M33.1 Other dermatomyositis
0.009 0.990 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.009 0.990 0.000
M34.9 Systemic sclerosis, unspecified
0.009 0.990 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.009 0.990 0.000
M34.0 Progressive systemic sclerosis
0.009 0.990 0.000
M24.59 Contracture of joint (Site unspecified)
0.009 0.990 0.000
M24.58 Contracture of joint (Other)
0.009 0.990 0.000
M24.57 Contracture of joint (Ankle and foot)
0.009 0.990 0.000
M24.56 Contracture of joint (Lower leg)
0.009 0.990 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.009 0.990 0.000
M24.53 Contracture of joint (Forearm)
0.009 0.990 0.000
M24.52 Contracture of joint (Upper arm)
0.009 0.990 0.000
M24.50 Contracture of joint (Multiple sites)
0.009 0.990 0.000
M25.79 Osteophyte (Site unspecified)
0.009 0.990 0.000
M25.73 Osteophyte (Forearm)
0.009 0.990 0.000
M25.72 Osteophyte (Upper arm)
0.009 0.990 0.000
M25.70 Osteophyte (Multiple sites)
0.009 0.990 0.000
M25.39 Other instability of joint (Site unspecified)
0.009 0.991 0.000
M25.38 Other instability of joint (Other)
0.009 0.991 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.009 0.991 0.000
M25.33 Other instability of joint (Forearm)
0.009 0.991 0.000
M25.32 Other instability of joint (Upper arm)
0.009 0.991 0.000
M25.30 Other instability of joint (Multiple sites)
0.009 0.991 0.000
D72.1 Eosinophilia
0.009 0.991 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.009 0.991 0.000
M25.88 Other specified joint disorders (Other)
0.009 0.991 0.000
M25.83 Other specified joint disorders (Forearm)
0.009 0.991 0.000
M25.82 Other specified joint disorders (Upper arm)
0.009 0.991 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.009 0.991 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.009 0.991 0.000
M84.0 Malunion of fracture
0.009 0.991 0.000
M34.8 Other forms of systemic sclerosis
0.009 0.991 0.000
M24.24 Disorder of ligament (Hand)
0.009 0.991 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.009 0.991 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.009 0.991 0.000
M20 Acquired deformities of fingers and toes
0.009 0.991 0.000
M33.9 Dermatopolymyositis, unspecified
0.009 0.991 0.000
M33.0 Juvenile dermatomyositis
0.009 0.991 0.000
M48.9 Spondylopathy, unspecified
0.009 0.991 0.000
M48.8 Other specified spondylopathies
0.009 0.991 0.000
M48.4 Fatigue fracture of vertebra
0.009 0.991 0.000
M48.3 Traumatic spondylopathy
0.009 0.991 0.000
M48.2 Kissing spine
0.009 0.991 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.009 0.991 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.009 0.991 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.009 0.991 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.009 0.991 0.000
D74 Methaemoglobinaemia
0.009 0.991 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.009 0.991 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.009 0.991 0.000
M79.63 Pain in limb (Forearm)
0.009 0.991 0.000
M85.64 Other cyst of bone (Hand)
0.009 0.991 0.000
M49 Spondylopathies in diseases classified elsewhere
0.009 0.991 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.009 0.991 0.000
M32.8 Other forms of systemic lupus erythematosus
0.009 0.991 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.009 0.991 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.009 0.991 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.009 0.991 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.009 0.991 0.000
M36.3 Arthropathy in other blood disorders
0.009 0.991 0.000
M36.2 Haemophilic arthropathy
0.009 0.991 0.000
M36.1 Arthropathy in neoplastic disease
0.009 0.991 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.009 0.991 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.009 0.991 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.009 0.991 0.000
M48.04 Spinal stenosis (Thoracic region)
0.009 0.991 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.009 0.991 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.009 0.991 0.000
M81.4 Drug-induced osteoporosis
0.009 0.991 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.009 0.991 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.009 0.991 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.009 0.991 0.000
M89.84 Other specified disorders of bone (Hand)
0.009 0.991 0.000
M89.83 Other specified disorders of bone (Forearm)
0.009 0.991 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.009 0.991 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.009 0.991 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.009 0.991 0.000
M33.2 Polymyositis
0.009 0.991 0.000
M45 Ankylosing spondylitis
0.009 0.991 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.009 0.991 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.009 0.991 0.000
M30.2 Juvenile polyarteritis
0.009 0.991 0.000
M30.0 Polyarteritis nodosa
0.009 0.991 0.000
M70-M79 Other soft tissue disorders
0.009 0.991 0.000
M25.31 Other instability of joint (Shoulder region)
0.009 0.991 0.000
M60 Myositis
0.009 0.991 0.000
M24.29 Disorder of ligament (Site unspecified)
0.009 0.991 0.000
M24.28 Disorder of ligament (Other)
0.009 0.991 0.000
M24.26 Disorder of ligament (Lower leg)
0.009 0.991 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.009 0.991 0.000
M24.22 Disorder of ligament (Upper arm)
0.009 0.991 0.000
M24.21 Disorder of ligament (Shoulder region)
0.009 0.991 0.000
M24.20 Disorder of ligament (Multiple sites)
0.009 0.991 0.000
M23.3 Other meniscus derangements
0.009 0.991 0.000
D61 Other aplastic anaemias
0.009 0.991 0.000
D55-D59 Haemolytic anaemias
0.009 0.991 0.000
M86.8 Other osteomyelitis
0.009 0.991 0.000
M20.3 Other deformity of hallux (acquired)
0.009 0.991 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.009 0.991 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.009 0.991 0.000
M25.86 Other specified joint disorders (Lower leg)
0.009 0.991 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.009 0.991 0.000
D73.5 Infarction of spleen
0.009 0.991 0.000
M84.9 Disorder of continuity of bone, unspecified
0.009 0.991 0.000
M84.8 Other disorders of continuity of bone
0.009 0.991 0.000
M84.4 Pathological fracture, not elsewhere classified
0.009 0.991 0.000
M84.3 Stress fracture, not elsewhere classified
0.009 0.991 0.000
M84.2 Delayed union of fracture
0.009 0.991 0.000
M80 Osteoporosis with pathological fracture
0.009 0.991 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.009 0.991 0.000
M31.9 Necrotising vasculopathy, unspecified
0.009 0.991 0.000
M31.8 Other specified necrotising vasculopathies
0.009 0.991 0.000
M31.7 Microscopic polyangiitis
0.009 0.991 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.009 0.991 0.000
M31.2 Lethal midline granuloma
0.009 0.991 0.000
M31.1 Thrombotic microangiopathy
0.009 0.991 0.000
M31.0 Hypersensitivity angiitis
0.009 0.991 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.009 0.991 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.009 0.991 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.009 0.991 0.000
M50.1 Cervical disk disorder with radiculopathy
0.009 0.991 0.000
M79.6 Pain in limb
0.009 0.991 0.000
D75 Other diseases of blood and blood-forming organs
0.009 0.991 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.009 0.991 0.000
D73.0 Hyposplenism
0.009 0.991 0.000
D72.9 Disorder of white blood cells, unspecified
0.009 0.991 0.000
D72.0 Genetic anomalies of leukocytes
0.009 0.991 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.009 0.991 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.008 0.991 0.000
M89.98 Disorder of bone, unspecified (Other)
0.008 0.991 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.008 0.991 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.008 0.991 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.008 0.991 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.008 0.991 0.000
M43 Other deforming dorsopathies
0.009 0.991 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.008 0.991 0.000
M24.79 Protrusio acetabuli-Site unspec
0.008 0.991 0.000
M24.78 Protrusio acetabuli-Other
0.008 0.991 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.008 0.991 0.000
M24.76 Protrusio acetabuli-Lower leg
0.008 0.991 0.000
M24.74 Protrusio acetabuli-Hand
0.008 0.991 0.000
M24.73 Protrusio acetabuli-Forearm
0.008 0.991 0.000
M24.72 Protrusio acetabuli-Upper arm
0.008 0.991 0.000
M24.71 Protrusio acetabuli-Shldr region
0.008 0.991 0.000
M24.70 Protrusio acetabuli-Mult sites
0.008 0.991 0.000
M31.3 Wegener's granulomatosis
0.008 0.991 0.000
M35.7 Hypermobility syndrome
0.009 0.991 0.000
D73.8 Other diseases of spleen
0.008 0.991 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.008 0.991 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.008 0.991 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.008 0.991 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.008 0.991 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.008 0.991 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.008 0.991 0.000
M54 Dorsalgia
0.008 0.991 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.008 0.992 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.008 0.992 0.000
C60-C63 Malignant neoplasms of male genital organs
0.008 0.992 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.008 0.992 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.008 0.992 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.008 0.992 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.008 0.992 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.008 0.992 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.008 0.992 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.008 0.992 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.008 0.992 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.008 0.992 0.000
M25.84 Other specified joint disorders (Hand)
0.008 0.992 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.008 0.992 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.008 0.992 0.000
M82.1 Osteoporosis in endocrine disorders
0.008 0.992 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.008 0.992 0.000
M87.8 Other osteonecrosis
0.008 0.992 0.000
M87.3 Other secondary osteonecrosis
0.008 0.992 0.000
M87.1 Osteonecrosis due to drugs
0.008 0.992 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.008 0.992 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.008 0.992 0.000
M23.1 Discoid meniscus (congenital)
0.008 0.992 0.000
M42 Spinal osteochondrosis
0.008 0.992 0.000
G43.9 Migraine, unspecified
0.008 0.992 0.000
M46.8 Other specified inflammatory spondylopathies
0.008 0.992 0.000
M46.5 Other infective spondylopathies
0.008 0.992 0.000
M46.2 Osteomyelitis of vertebra
0.008 0.992 0.000
M46.0 Spinal enthesopathy
0.008 0.992 0.000
M20.4 Other hammer toe(s) (acquired)
0.008 0.992 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.008 0.992 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.008 0.992 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.008 0.992 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.008 0.992 0.000
M85.69 Other cyst of bone (Site unspecified)
0.008 0.992 0.000
M85.68 Other cyst of bone (Other)
0.008 0.992 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.008 0.992 0.000
M85.66 Other cyst of bone (Lower leg)
0.008 0.992 0.000
M85.63 Other cyst of bone (Forearm)
0.008 0.992 0.000
M85.62 Other cyst of bone (Upper arm)
0.008 0.992 0.000
M85.61 Other cyst of bone (Shoulder region)
0.008 0.992 0.000
M85.60 Other cyst of bone (Multiple sites)
0.008 0.992 0.000
M79.8 Other specified soft tissue disorders
0.008 0.992 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.008 0.992 0.000
M84.02 Malunion of fracture (Upper arm)
0.008 0.992 0.000
C61 Malignant neoplasm of prostate
0.008 0.992 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.008 0.992 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.008 0.992 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.008 0.992 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.008 0.992 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.008 0.992 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.008 0.992 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.008 0.992 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.008 0.992 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.008 0.992 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.008 0.992 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.008 0.992 0.000
M24.68 Ankylosis of joint (Other)
0.008 0.992 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.008 0.992 0.000
M24.66 Ankylosis of joint (Lower leg)
0.008 0.992 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.008 0.992 0.000
M24.64 Ankylosis of joint (Hand)
0.008 0.992 0.000
M24.63 Ankylosis of joint (Forearm)
0.008 0.992 0.000
M24.62 Ankylosis of joint (Upper arm)
0.008 0.992 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.008 0.992 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.008 0.992 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.008 0.992 0.000
M24.98 Joint derangement, unspecified (Other)
0.008 0.992 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.008 0.992 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.008 0.992 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.008 0.992 0.000
M24.94 Joint derangement, unspecified (Hand)
0.008 0.992 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.008 0.992 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.008 0.992 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.008 0.992 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.008 0.992 0.000
M24.07 Loose body in joint (Ankle and foot)
0.008 0.992 0.000
C62.1 Descended testis
0.008 0.992 0.000
C62.0 Undescended testis
0.008 0.992 0.000
M40.5 Lordosis, unspecified
0.008 0.992 0.000
M83.9 Adult osteomalacia, unspecified
0.008 0.992 0.000
M83.8 Other adult osteomalacia
0.008 0.992 0.000
M83.5 Other drug-induced osteomalacia in adults
0.008 0.992 0.000
M83.4 Aluminum bone disease
0.008 0.992 0.000
M83.3 Adult osteomalacia due to malnutrition
0.008 0.992 0.000
M83.2 Adult osteomalacia due to malabsorption
0.008 0.992 0.000
M83.1 Senile osteomalacia
0.008 0.992 0.000
M83.0 Puerperal osteomalacia
0.008 0.992 0.000
M23.8 Other internal derangements of knee
0.008 0.992 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.008 0.992 0.000
D73.9 Disease of spleen, unspecified
0.008 0.992 0.000
D73.4 Cyst of spleen
0.008 0.992 0.000
D73.3 Abscess of spleen
0.008 0.992 0.000
D73.2 Chronic congestive splenomegaly
0.008 0.992 0.000
D73.1 Hypersplenism
0.008 0.992 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.008 0.992 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.008 0.992 0.000
M89.38 Hypertrophy of bone (Other)
0.008 0.992 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.008 0.992 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.008 0.992 0.000
M89.34 Hypertrophy of bone (Hand)
0.008 0.992 0.000
M89.33 Hypertrophy of bone (Forearm)
0.008 0.992 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.008 0.992 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.008 0.992 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.008 0.992 0.000
M23.0 Cystic meniscus
0.008 0.992 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.008 0.992 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.008 0.992 0.000
M61 Calcification and ossification of muscle
0.008 0.992 0.000
M24.09 Loose body in joint (Site unspecified)
0.008 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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