TreeWAS – Variant ID: rs79489058

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O60-O75 Complications of labour and delivery	0.146	0.854
O72 Postpartum haemorrhage	0.143	0.857
O72.1 Other immediate postpartum haemorrhage	0.137	0.863
Chapter XV Pregnancy, childbirth and the puerperium	0.132	0.868
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.131	0.869
O68 Labour and delivery complicated by foetal stress [distress]	0.130	0.870
O63 Long labour	0.128	0.872
O72.0 Third-stage haemorrhage	0.124	0.876
O62 Abnormalities of forces of labour	0.121	0.879
O41 Other disorders of amniotic fluid and membranes	0.120	0.880
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.119	0.881
O70 Perineal laceration during delivery	0.119	0.881
O34 Maternal care for known or suspected abnormality of pelvic organs	0.118	0.882
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.116	0.884
O63.1 Prolonged second stage (of labour)	0.112	0.888
O64 Obstructed labour due to malposition and malpresentation of foetus	0.111	0.889
O70.1 Second degree perineal laceration during delivery	0.110	0.890
O94-O99 Other obstetric conditions, not elsewhere classified	0.109	0.891
O41.0 Oligohydramnios	0.109	0.891
O69 Labour and delivery complicated by umbilical cord complications	0.109	0.891
O34.2 Maternal care due to uterine scar from previous surgery	0.109	0.891
O30 Multiple gestation	0.108	0.892
O47 False labour	0.107	0.893
O74 Complications of anaesthesia during labour and delivery	0.105	0.895
O71 Other obstetric trauma	0.105	0.895
O65 Obstructed labour due to maternal pelvic abnormality	0.105	0.895
O60 Preterm delivery	0.105	0.895
O61 Failed induction of labour	0.104	0.896
O72.3 Postpartum coagulation defects	0.103	0.897
O63.9 Long labour, unspecified	0.102	0.898
O66 Other obstructed labour	0.100	0.900
O85-O92 Complications predominantly related to the puerperium	0.100	0.900
O67.9 Intrapartum haemorrhage, unspecified	0.100	0.900
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.100	0.900
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.099	0.901
O62.2 Other uterine inertia	0.099	0.901
O42 Premature rupture of membranes	0.098	0.902
O41.8 Other specified disorders of amniotic fluid and membranes	0.098	0.902
O44 Placenta praevia	0.098	0.902
O73 Retained placenta and membranes, without haemorrhage	0.098	0.902
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.096	0.904
O72.2 Delayed and secondary postpartum haemorrhage	0.096	0.904
O35 Maternal care for known or suspected foetal abnormality and damage	0.096	0.904
O20-O29 Other maternal disorders predominantly related to pregnancy	0.095	0.905
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.094	0.905
O45 Premature separation of placenta [abruptio placentae]	0.094	0.906
O43 Placental disorders	0.094	0.906
O33 Maternal care for known or suspected disproportion	0.094	0.906
O31 Complications specific to multiple gestation	0.094	0.906
O40 Polyhydramnios	0.094	0.906
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.093	0.907
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.093	0.907
O48 Prolonged pregnancy	0.093	0.907
O63.2 Delayed delivery of second twin, triplet, etc.	0.092	0.908
O62.3 Precipitate labour	0.092	0.908
O75 Other complications of labour and delivery, not elsewhere classified	0.092	0.908
O30.0 Twin pregnancy	0.092	0.908
O47.9 False labour, unspecified	0.091	0.909
O63.0 Prolonged first stage (of labour)	0.089	0.911
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.089	0.911
O80-O84 Delivery	0.089	0.911
O70.9 Perineal laceration during delivery, unspecified	0.087	0.913
O62.9 Abnormality of forces of labour, unspecified	0.087	0.913
O62.8 Other abnormalities of forces of labour	0.087	0.913
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.087	0.913
O62.1 Secondary uterine inertia	0.087	0.913
O62.0 Primary inadequate contractions	0.087	0.913
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.086	0.913
O41.1 Infection of amniotic sac and membranes	0.086	0.913
O67.8 Other intrapartum haemorrhage	0.086	0.914
O67.0 Intrapartum haemorrhage with coagulation defect	0.086	0.914
O32 Maternal care for known or suspected malpresentation of foetus	0.086	0.914
O70.3 Fourth degree perineal laceration during delivery	0.085	0.914
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.084	0.915
O34.8 Maternal care for other abnormalities of pelvic organs	0.084	0.915
O34.7 Maternal care for abnormality of vulva and perineum	0.084	0.915
O34.6 Maternal care for abnormality of vagina	0.084	0.915
O34.5 Maternal care for other abnormalities of gravid uterus	0.084	0.915
O34.4 Maternal care for other abnormalities of cervix	0.084	0.915
O34.3 Maternal care for cervical incompetence	0.084	0.915
O34.1 Maternal care for tumour of corpus uteri	0.084	0.915
O34.0 Maternal care for congenital malformation of uterus	0.084	0.915
O42.9 Premature rupture of membranes, unspecified	0.084	0.916
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.083	0.917
O64.1 Obstructed labour due to breech presentation	0.083	0.917
O46 Antepartum haemorrhage, not elsewhere classified	0.083	0.917
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.081	0.919
O69.2 Labour and delivery complicated by other cord entanglement	0.080	0.919
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.080	0.920
O64.8 Obstructed labour due to other malposition and malpresentation	0.080	0.920
O64.5 Obstructed labour due to compound presentation	0.080	0.920
O64.4 Obstructed labour due to shoulder presentation	0.080	0.920
O64.3 Obstructed labour due to brow presentation	0.080	0.920
O64.2 Obstructed labour due to face presentation	0.080	0.920
O69.1 Labour and delivery complicated by cord around neck, with compression	0.079	0.921
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.079	0.921
O97 Death from sequelae of direct obstetric causes	0.079	0.921
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.079	0.921
O95 Obstetric death of unspecified cause	0.079	0.921
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.079	0.921
O36 Maternal care for other known or suspected foetal problems	0.079	0.921
O69.9 Labour and delivery complicated by cord complication, unspecified	0.078	0.922
O69.8 Labour and delivery complicated by other cord complications	0.078	0.922
O69.5 Labour and delivery complicated by vascular lesion of cord	0.078	0.922
O69.4 Labour and delivery complicated by vasa praevia	0.078	0.922
O69.3 Labour and delivery complicated by short cord	0.078	0.922
O69.0 Labour and delivery complicated by prolapse of cord	0.078	0.922
O30.9 Multiple gestation, unspecified	0.078	0.922
O30.8 Other multiple gestation	0.078	0.922
O30.2 Quadruplet pregnancy	0.078	0.922
O30.1 Triplet pregnancy	0.078	0.922
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.077	0.923
O70.2 Third degree perineal laceration during delivery	0.077	0.923
O90 Complications of the puerperium, not elsewhere classified	0.077	0.923
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.077	0.923
O47.0 False labour before 37 completed weeks of gestation	0.077	0.923
O47.1 False labour at or after 37 completed weeks of gestation	0.077	0.923
O60.3 Preterm delivery without spontaneous labour	0.075	0.924
O60.2 Preterm spontaneous labour with term delivery	0.075	0.924
O60.1 Preterm spontaneous labour with preterm delivery	0.075	0.924
O60.0 Preterm labour without delivery	0.075	0.924
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.075	0.924
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.075	0.924
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.075	0.924
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.075	0.924
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.075	0.924
O65.2 Obstructed labour due to pelvic inlet contraction	0.075	0.924
O65.1 Obstructed labour due to generally contracted pelvis	0.075	0.924
O65.0 Obstructed labour due to deformed pelvis	0.075	0.924
O71.9 Obstetric trauma, unspecified	0.075	0.924
O71.8 Other specified obstetric trauma	0.075	0.924
O71.7 Obstetric haematoma of pelvis	0.075	0.924
O71.6 Obstetric damage to pelvic joints and ligaments	0.075	0.924
O71.5 Other obstetric injury to pelvic organs	0.075	0.924
O71.4 Obstetric high vaginal laceration alone	0.075	0.924
O71.3 Obstetric laceration of cervix	0.075	0.924
O71.2 Postpartum inversion of uterus	0.075	0.924
O71.1 Rupture of uterus during labour	0.075	0.924
O71.0 Rupture of uterus before onset of labour	0.075	0.924
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.075	0.924
O74.8 Other complications of anaesthesia during labour and delivery	0.075	0.924
O74.7 Failed or difficult intubation during labour and delivery	0.075	0.924
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.075	0.924
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.075	0.924
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.075	0.924
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.075	0.924
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.075	0.924
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.075	0.924
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.075	0.924
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.075	0.924
O61.9 Failed induction of labour, unspecified	0.075	0.925
O61.8 Other failed induction of labour	0.075	0.925
O61.1 Failed instrumental induction of labour	0.075	0.925
O61.0 Failed medical induction of labour	0.074	0.926
O44.1 Placenta praevia with haemorrhage	0.074	0.926
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.074	0.926
O24 Diabetes mellitus in pregnancy	0.073	0.927
O00-O08 Pregnancy with abortive outcome	0.073	0.927
O16 Unspecified maternal hypertension	0.072	0.928
O66.9 Obstructed labour, unspecified	0.072	0.928
O66.8 Other specified obstructed labour	0.072	0.928
O66.4 Failed trial of labour, unspecified	0.072	0.928
O66.3 Obstructed labour due to other abnormalities of foetus	0.072	0.928
O66.2 Obstructed labour due to unusually large foetus	0.072	0.928
O66.1 Obstructed labour due to locked twins	0.072	0.928
O66.0 Obstructed labour due to shoulder dystocia	0.072	0.928
O92 Other disorders of breast and lactation associated with childbirth	0.072	0.928
O91 Infections of breast associated with childbirth	0.072	0.928
O89 Complications of anaesthesia during the puerperium	0.072	0.928
O88 Obstetric embolism	0.072	0.928
O87 Venous complications in the puerperium	0.072	0.928
O86 Other puerperal infections	0.072	0.928
O85 Puerperal sepsis	0.072	0.928
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.072	0.928
O15 Eclampsia	0.071	0.929
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.071	0.929
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.071	0.929
O75.0 Maternal distress during labour and delivery	0.071	0.929
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.071	0.929
O42.2 Premature rupture of membranes, labour delayed by therapy	0.071	0.929
O21 Excessive vomiting in pregnancy	0.070	0.929
O44.0 Placenta praevia specified as without haemorrhage	0.070	0.930
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.070	0.930
O20 Haemorrhage in early pregnancy	0.069	0.931
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.069	0.931
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.069	0.931
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.069	0.931
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.069	0.931
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.069	0.931
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.069	0.931
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.069	0.931
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.069	0.931
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.069	0.931
O29 Complications of anaesthesia during pregnancy	0.068	0.932
O28 Abnormal findings on antenatal screening of mother	0.068	0.932
O23 Infections of genito-urinary tract in pregnancy	0.068	0.932
O22 Venous complications in pregnancy	0.068	0.932
O25 Malnutrition in pregnancy	0.068	0.932
O12.0 Gestational oedema	0.068	0.932
O31.8 Other complications specific to multiple gestation	0.067	0.932
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.067	0.932
O31.1 Continuing pregnancy after abortion of one foetus or more	0.067	0.932
O31.0 Papyraceous foetus	0.067	0.932
O33.9 Maternal care for disproportion, unspecified	0.067	0.932
O33.8 Maternal care for disproportion of other origin	0.067	0.932
O33.7 Maternal care for disproportion due to other foetal deformities	0.067	0.932
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.067	0.932
O33.5 Maternal care for disproportion due to unusually large foetus	0.067	0.932
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.067	0.932
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.067	0.932
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.067	0.932
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.067	0.932
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.067	0.932
O43.9 Placental disorder, unspecified	0.067	0.932
O43.8 Other placental disorders	0.067	0.932
O43.2 Morbidly adherent placenta	0.067	0.932
O43.1 Malformation of placenta	0.067	0.932
O43.0 Placental transfusion syndromes	0.067	0.932
O45.9 Premature separation of placenta, unspecified	0.067	0.932
O45.8 Other premature separation of placenta	0.067	0.932
O45.0 Premature separation of placenta with coagulation defect	0.067	0.932
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.067	0.933
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.067	0.933
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.067	0.933
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.067	0.933
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.067	0.933
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.067	0.933
O32.8 Maternal care for other malpresentation of foetus	0.067	0.933
O75.9 Complication of labour and delivery, unspecified	0.066	0.934
O75.5 Delayed delivery after artificial rupture of membranes	0.066	0.934
O75.4 Other complications of obstetric surgery and procedures	0.066	0.934
O75.3 Other infection during labour	0.066	0.934
O75.2 Pyrexia during labour, not elsewhere classified	0.066	0.934
O75.1 Shock during or following labour and delivery	0.066	0.934
O82 Single delivery by Caesarean section	0.065	0.935
O84 Multiple delivery	0.064	0.936
O83 Other assisted single delivery	0.064	0.936
O81 Single delivery by forceps and vacuum extractor	0.064	0.936
O73.0 Retained placenta, without haemorrhage	0.062	0.937
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.062	0.937
O70.0 First degree perineal laceration during delivery	0.062	0.938
O32.9 Maternal care for malpresentation of foetus, unspecified	0.062	0.938
O32.6 Maternal care for compound presentation	0.062	0.938
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.062	0.938
O32.4 Maternal care for high head at term	0.062	0.938
O32.3 Maternal care for face, brow and chin presentation	0.062	0.938
O32.2 Maternal care for transverse and oblique lie	0.062	0.938
O32.0 Maternal care for unstable lie	0.062	0.938
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.061	0.938
O75.8 Other specified complications of labour and delivery	0.061	0.939
O90.8 Other complications of the puerperium, not elsewhere classified	0.061	0.939
O46.8 Other antepartum haemorrhage	0.060	0.940
O46.0 Antepartum haemorrhage with coagulation defect	0.060	0.940
O36.5 Maternal care for poor foetal growth	0.059	0.941
O12.2 Gestational oedema with proteinuria	0.058	0.942
O12.1 Gestational proteinuria	0.058	0.942
O24.4 Diabetes mellitus arising in pregnancy	0.058	0.942
O26 Maternal care for other conditions predominantly related to pregnancy	0.057	0.943
O75.7 Vaginal delivery following previous Caesarean section	0.057	0.943
O36.8 Maternal care for other specified foetal problems	0.057	0.943
O96.9 Death from unspecified obstetric cause	0.056	0.943
O96.1 Death from indirect obstetric cause	0.056	0.943
O96.0 Death from direct obstetric cause	0.056	0.943
O97.9 Death from sequelae of obstetric cause, unspecified	0.056	0.943
O97.1 Death from sequelae of indirect obstetric cause	0.056	0.943
O97.0 Death from sequelae of direct obstetric cause	0.056	0.943
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.056	0.943
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.056	0.943
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.056	0.943
O36.4 Maternal care for intra-uterine death	0.056	0.943
O36.3 Maternal care for signs of foetal hypoxia	0.056	0.943
O36.2 Maternal care for hydrops foetalis	0.056	0.943
O36.1 Maternal care for other isoimmunisation	0.056	0.943
O90.9 Complication of the puerperium, unspecified	0.055	0.944
O90.5 Postpartum thyroiditis	0.055	0.944
O90.4 Postpartum acute renal failure	0.055	0.944
O90.3 Cardiomyopathy in the puerperium	0.055	0.944
O90.2 Haematoma of obstetric wound	0.055	0.944
O90.1 Disruption of perineal obstetric wound	0.055	0.944
O90.0 Disruption of Caesarean section wound	0.055	0.944
O80 Single spontaneous delivery	0.055	0.945
O00 Ectopic pregnancy	0.055	0.945
O20.0 Threatened abortion	0.054	0.946
O21.0 Mild hyperemesis gravidarum	0.053	0.947
O36.9 Maternal care for foetal problem, unspecified	0.053	0.947
O24.9 Diabetes mellitus in pregnancy, unspecified	0.053	0.947
O24.3 Pre-existing diabetes mellitus, unspecified	0.053	0.947
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.053	0.947
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.053	0.947
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.053	0.947
O08 Complications following abortion and ectopic and molar pregnancy	0.053	0.947
O07 Failed attempted abortion	0.053	0.947
O06 Unspecified abortion	0.053	0.947
O05 Other abortion	0.053	0.947
O01 Hydatidiform mole	0.053	0.947
O14.9 Preeclampsia, unspecified	0.052	0.948
O86.8 Other specified puerperal infections	0.052	0.948
O86.4 Pyrexia of unknown origin following delivery	0.052	0.948
O86.3 Other genito-urinary tract infections following delivery	0.052	0.948
O86.2 Urinary tract infection following delivery	0.052	0.948
O86.1 Other infection of genital tract following delivery	0.052	0.948
O86.0 Infection of obstetric surgical wound	0.052	0.948
O87.9 Venous complication in the puerperium, unspecified	0.052	0.948
O87.8 Other venous complications in the puerperium	0.052	0.948
O87.3 Cerebral venous thrombosis in the puerperium	0.052	0.948
O87.2 Haemorrhoids in the puerperium	0.052	0.948
O87.1 Deep phlebothrombosis in the puerperium	0.052	0.948
O87.0 Superficial thrombophlebitis in the puerperium	0.052	0.948
O88.8 Other obstetric embolism	0.052	0.948
O88.3 Obstetric pyaemic and septic embolism	0.052	0.948
O88.2 Obstetric blood-clot embolism	0.052	0.948
O88.1 Amniotic fluid embolism	0.052	0.948
O88.0 Obstetric air embolism	0.052	0.948
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.052	0.948
O89.8 Other complications of anaesthesia during the puerperium	0.052	0.948
O89.6 Failed or difficult intubation during the puerperium	0.052	0.948
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.052	0.948
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.052	0.948
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.052	0.948
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.052	0.948
O89.1 Cardiac complications of anaesthesia during the puerperium	0.052	0.948
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.052	0.948
O91.2 Nonpurulent mastitis associated with childbirth	0.052	0.948
O91.1 Abscess of breast associated with childbirth	0.052	0.948
O91.0 Infection of nipple associated with childbirth	0.052	0.948
O92.7 Other and unspecified disorders of lactation	0.052	0.948
O92.6 Galactorrhoea	0.052	0.948
O92.5 Suppressed lactation	0.052	0.948
O92.4 Hypogalactia	0.052	0.948
O92.3 Agalactia	0.052	0.948
O92.2 Other and unspecified disorders of breast associated with childbirth	0.052	0.948
O92.1 Cracked nipple associated with childbirth	0.052	0.948
O92.0 Retracted nipple associated with childbirth	0.052	0.948
O14.2 HELLP syndrome	0.052	0.948
O14.1 Severe preeclampsia	0.052	0.948
O14.0 Moderate preeclampsia	0.052	0.948
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.051	0.949
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.051	0.949
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.051	0.949
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.051	0.949
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.051	0.949
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.051	0.949
O15.9 Eclampsia, unspecified as to time period	0.051	0.949
O15.2 Eclampsia in the puerperium	0.051	0.949
O15.1 Eclampsia in labour	0.051	0.949
O15.0 Eclampsia in pregnancy	0.051	0.949
O82.0 Delivery by elective Caesarean section	0.051	0.949
O02 Other abnormal products of conception	0.051	0.949
O21.9 Vomiting of pregnancy, unspecified	0.051	0.949
O21.8 Other vomiting complicating pregnancy	0.051	0.949
O21.2 Late vomiting of pregnancy	0.051	0.949
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.051	0.949
O36.6 Maternal care for excessive foetal growth	0.050	0.949
O04 Medical abortion	0.051	0.949
O36.0 Maternal care for rhesus isoimmunisation	0.050	0.950
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.050	0.950
O20.8 Other haemorrhage in early pregnancy	0.050	0.950
O22.9 Venous complication in pregnancy, unspecified	0.049	0.951
O22.8 Other venous complications in pregnancy	0.049	0.951
O22.5 Cerebral venous thrombosis in pregnancy	0.049	0.951
O22.4 Haemorrhoids in pregnancy	0.049	0.951
O22.3 Deep phlebothrombosis in pregnancy	0.049	0.951
O22.2 Superficial thrombophlebitis in pregnancy	0.049	0.951
O22.1 Genital varices in pregnancy	0.049	0.951
O22.0 Varicose veins of lower extremity in pregnancy	0.049	0.951
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.049	0.951
O23.5 Infections of the genital tract in pregnancy	0.049	0.951
O23.4 Unspecified infection of urinary tract in pregnancy	0.049	0.951
O23.3 Infections of other parts of urinary tract in pregnancy	0.049	0.951
O23.2 Infections of urethra in pregnancy	0.049	0.951
O23.1 Infections of bladder in pregnancy	0.049	0.951
O23.0 Infections of kidney in pregnancy	0.049	0.951
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.049	0.951
O28.8 Other abnormal findings on antenatal screening of mother	0.049	0.951
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.049	0.951
O28.4 Abnormal radiological finding on antenatal screening of mother	0.049	0.951
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.049	0.951
O28.2 Abnormal cytological finding on antenatal screening of mother	0.049	0.951
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.049	0.951
O28.0 Abnormal haematological finding on antenatal screening of mother	0.049	0.951
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.049	0.951
O29.8 Other complications of anaesthesia during pregnancy	0.049	0.951
O29.6 Failed or difficult intubation during pregnancy	0.049	0.951
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.049	0.951
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.049	0.951
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.049	0.951
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.049	0.951
O29.1 Cardiac complications of anaesthesia during pregnancy	0.049	0.951
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.049	0.951
O46.9 Antepartum haemorrhage, unspecified	0.049	0.951
O82.9 Delivery by Caesarean section, unspecified	0.047	0.953
O82.8 Other single delivery by Caesarean section	0.047	0.953
O82.2 Delivery by Caesarean hysterectomy	0.047	0.953
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.046	0.953
O81.5 Delivery by combination of forceps and vacuum extractor	0.046	0.954
O81.4 Vacuum extractor delivery	0.046	0.954
O81.3 Other and unspecified forceps delivery	0.046	0.954
O81.2 Mid-cavity forceps with rotation	0.046	0.954
O81.1 Mid-cavity forceps delivery	0.046	0.954
O81.0 Low forceps delivery	0.046	0.954
O83.9 Assisted single delivery, unspecified	0.046	0.954
O83.8 Other specified assisted single delivery	0.046	0.954
O83.4 Destructive operation for delivery	0.046	0.954
O83.3 Delivery of viable foetus in abdominal pregnancy	0.046	0.954
O83.2 Other manipulation-assisted delivery	0.046	0.954
O83.1 Other assisted breech delivery	0.046	0.954
O83.0 Breech extraction	0.046	0.954
O84.9 Multiple delivery, unspecified	0.046	0.954
O84.8 Other multiple delivery	0.046	0.954
O84.2 Multiple delivery, all by Caesarean section	0.046	0.954
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.046	0.954
O84.0 Multiple delivery, all spontaneous	0.046	0.954
O20.9 Haemorrhage in early pregnancy, unspecified	0.045	0.954
O80.8 Other single spontaneous delivery	0.045	0.955
O32.1 Maternal care for breech presentation	0.045	0.955
O82.1 Delivery by emergency Caesarean section	0.043	0.956
O00.9 Ectopic pregnancy, unspecified	0.042	0.958
O26.8 Other specified pregnancy-related conditions	0.042	0.958
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.041	0.959
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.041	0.959
O26.5 Maternal hypotension syndrome	0.041	0.959
O26.4 Herpes gestationis	0.041	0.959
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.041	0.959
O26.2 Pregnancy care of habitual aborter	0.041	0.959
O26.1 Low weight gain in pregnancy	0.041	0.959
O26.0 Excessive weight gain in pregnancy	0.041	0.959
O80.1 Spontaneous breech delivery	0.040	0.960
O00.8 Other ectopic pregnancy	0.039	0.960
O00.2 Ovarian pregnancy	0.039	0.960
O00.0 Abdominal pregnancy	0.039	0.960
O00.1 Tubal pregnancy	0.038	0.961
O80.9 Single spontaneous delivery, unspecified	0.038	0.962
O01.9 Hydatidiform mole, unspecified	0.038	0.962
O01.1 Incomplete and partial hydatidiform mole	0.038	0.962
O01.0 Classical hydatidiform mole	0.038	0.962
O05.9 Complete or unspecified, without complication	0.038	0.962
O05.8 Complete or unspecified, with other and unspecified complications	0.038	0.962
O05.7 Complete or unspecified, complicated by embolism	0.038	0.962
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.038	0.962
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.038	0.962
O05.4 Incomplete, without complication	0.038	0.962
O05.3 Incomplete, with other and unspecified complications	0.038	0.962
O05.2 Incomplete, complicated by embolism	0.038	0.962
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.038	0.962
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.038	0.962
O06.9 Complete or unspecified, without complication	0.038	0.962
O06.8 Complete or unspecified, with other and unspecified complications	0.038	0.962
O06.7 Complete or unspecified, complicated by embolism	0.038	0.962
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.038	0.962
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.038	0.962
O06.4 Incomplete, without complication	0.038	0.962
O06.3 Incomplete, with other and unspecified complications	0.038	0.962
O06.2 Incomplete, complicated by embolism	0.038	0.962
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.038	0.962
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.038	0.962
O07.9 Other and unspecified failed attempted abortion, without complication	0.038	0.962
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.038	0.962
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.038	0.962
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.038	0.962
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.038	0.962
O07.4 Failed medical abortion, without complication	0.038	0.962
O07.3 Failed medical abortion, with other and unspecified complications	0.038	0.962
O07.2 Failed medical abortion, complicated by embolism	0.038	0.962
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.038	0.962
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.038	0.962
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.038	0.962
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.038	0.962
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.038	0.962
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.038	0.962
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.038	0.962
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.038	0.962
O08.3 Shock following abortion and ectopic and molar pregnancy	0.038	0.962
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.038	0.962
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.038	0.962
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.038	0.962
O02.9 Abnormal product of conception, unspecified	0.037	0.963
O02.8 Other specified abnormal products of conception	0.037	0.963
O02.0 Blighted ovum and nonhydatidiform mole	0.037	0.963
O04.8 Complete or unspecified, with other and unspecified complications	0.036	0.963
O04.7 Complete or unspecified, complicated by embolism	0.036	0.963
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.036	0.963
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.036	0.963
O04.4 Incomplete, without complication	0.036	0.963
O04.3 Incomplete, with other and unspecified complications	0.036	0.963
O04.2 Incomplete, complicated by embolism	0.036	0.963
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.036	0.963
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.036	0.963
O02.1 Missed abortion	0.035	0.965
O04.9 Complete or unspecified, without complication	0.034	0.966
O03 Spontaneous abortion	0.033	0.966
O26.9 Pregnancy-related condition, unspecified	0.030	0.970
S22.30 Fracture of rib (closed)	0.030	0.970

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations