TreeWAS – Variant ID: rs80337801

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z96.1 Presence of intraocular lens	0.042	0.958	0.000
L40.9 Psoriasis, unspecified	0.020	0.980	0.000
Z96 Presence of other functional implants	0.015	0.985	0.000
Z96.0 Presence of urogenital implants	0.015	0.985	0.000
Z96.2 Presence of otological and audiological implants	0.012	0.988	0.000
L40 Psoriasis	0.012	0.988	0.000
Z96.9 Presence of functional implant, unspecified	0.011	0.989	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.011	0.989	0.000
Z96.4 Presence of endocrine implants	0.011	0.989	0.000
Z96.3 Presence of artificial larynx	0.011	0.989	0.000
D50.8 Other iron deficiency anaemias	0.011	0.989	0.000
L40.5 Arthropathic psoriasis	0.010	0.990	0.000
Z96.7 Presence of other bone and tendon implants	0.009	0.990	0.000
H65.3 Chronic mucoid otitis media	0.009	0.991	0.000
L40.8 Other psoriasis	0.009	0.991	0.000
L40.4 Guttate psoriasis	0.009	0.991	0.000
L40.3 Pustulosis palmaris et plantaris	0.009	0.991	0.000
L40.2 Acrodermatitis continua	0.009	0.991	0.000
L40.1 Generalised pustular psoriasis	0.009	0.991	0.000
H91.9 Hearing loss, unspecified	0.008	0.992	0.000
L40.0 Psoriasis vulgaris	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.008	0.992	0.000
Z96.8 Presence of other specified functional implants	0.007	0.992	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.007	0.993	0.000
H91 Other hearing loss	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.006	0.994	0.000
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
D50 Iron deficiency anaemia	0.006	0.994	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.994	0.006
L40-L45 Papulosquamous disorders	0.005	0.994	0.000
H50.1 Divergent concomitant strabismus	0.005	0.995	0.000
H65.4 Other chronic nonsuppurative otitis media	0.005	0.995	0.000
H66.9 Otitis media, unspecified	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
H66 Suppurative and unspecified otitis media	0.005	0.995	0.000
I50.0 Congestive heart failure	0.005	0.995	0.000
H90-H95 Other disorders of ear	0.005	0.995	0.000
M23.3 Other meniscus derangements	0.005	0.995	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
D61.9 Aplastic anaemia, unspecified	0.005	0.995	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.995	0.000
H91.8 Other specified hearing loss	0.005	0.995	0.000
H91.3 Deaf mutism, not elsewhere classified	0.005	0.995	0.000
H91.2 Sudden idiopathic hearing loss	0.005	0.995	0.000
H91.1 Presbycusis	0.005	0.995	0.000
H91.0 Ototoxic hearing loss	0.005	0.995	0.000
L42 Pityriasis rosea	0.005	0.995	0.000
D64.9 Anaemia, unspecified	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
D61 Other aplastic anaemias	0.005	0.995	0.000
D50-D53 Nutritional anaemias	0.005	0.995	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.005	0.995	0.000
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
D64 Other anaemias	0.005	0.995	0.000
H50 Other strabismus	0.005	0.995	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.004	0.996	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.004	0.996	0.000
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.004	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
L44 Other papulosquamous disorders	0.004	0.996	0.000
L41 Parapsoriasis	0.004	0.996	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.004	0.996	0.000
H90.5 Sensorineural hearing loss, unspecified	0.004	0.996	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
H50.9 Strabismus, unspecified	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.004	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.004	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.004	0.996	0.000
H66.0 Acute suppurative otitis media	0.004	0.996	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.996	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
M23.37 Other meniscus derangements-Capsular lig	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.004	0.996	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.004	0.996	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.004	0.996	0.000
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.996	0.000
D61.8 Other specified aplastic anaemias	0.003	0.996	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.996	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.996	0.000
D61.1 Drug-induced aplastic anaemia	0.003	0.996	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.996	0.000
D53 Other nutritional anaemias	0.004	0.996	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
H52.2 Astigmatism	0.004	0.996	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.996	0.000
D52 Folate deficiency anaemia	0.004	0.996	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.004	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.996	0.000
D64.8 Other specified anaemias	0.003	0.996	0.000
D64.4 Congenital dyserythropoietic anaemia	0.003	0.996	0.000
D64.3 Other sideroblastic anaemias	0.003	0.996	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.996	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.996	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.996	0.000
H50.8 Other specified strabismus	0.003	0.996	0.000
H50.6 Mechanical strabismus	0.003	0.996	0.000
H50.5 Heterophoria	0.003	0.996	0.000
H50.4 Other and unspecified heterotropia	0.003	0.996	0.000
H50.3 Intermittent heterotropia	0.003	0.996	0.000
H50.2 Vertical strabismus	0.003	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
H49 Paralytic strabismus	0.003	0.996	0.000
D66 Hereditary factor VIII deficiency	0.003	0.996	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
M25.46 Effusion of joint (Lower leg)	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.003	0.997	0.000
L41.9 Parapsoriasis, unspecified	0.003	0.997	0.000
L41.8 Other parapsoriasis	0.003	0.997	0.000
L41.5 Retiform parapsoriasis	0.003	0.997	0.000
L41.4 Large plaque parapsoriasis	0.003	0.997	0.000
L41.3 Small plaque parapsoriasis	0.003	0.997	0.000
L41.2 Lymphomatoid papulosis	0.003	0.997	0.000
L41.1 Pityriasis lichenoides chronica	0.003	0.997	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.003	0.997	0.000
L44.9 Papulosquamous disorder, unspecified	0.003	0.997	0.000
L44.8 Other specified papulosquamous disorders	0.003	0.997	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.003	0.997	0.000
L44.3 Lichen ruber moniliformis	0.003	0.997	0.000
L44.2 Lichen striatus	0.003	0.997	0.000
L44.1 Lichen nitidus	0.003	0.997	0.000
L44.0 Pityriasis rubra pilaris	0.003	0.997	0.000
H50.0 Convergent concomitant strabismus	0.003	0.997	0.000
H52.3 Anisometropia and aniseikonia	0.003	0.997	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.997	0.003
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
M22.8 Other disorders of patella	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
H52.0 Hypermetropia	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
Z90.1 Acquired absence of breast(s)	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
M23 Internal derangement of knee	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
H51 Other disorders of binocular movement	0.003	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.003	0.997	0.000
H52.6 Other disorders of refraction	0.003	0.997	0.000
H52.5 Disorders of accommodation	0.003	0.997	0.000
H52.4 Presbyopia	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.003	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
N20.0 Calculus of kidney	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.003	0.997	0.000
D52.1 Drug-induced folate deficiency anaemia	0.003	0.997	0.000
D52.0 Dietary folate deficiency anaemia	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.003	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.997	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.997	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.003	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
D68 Other coagulation defects	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
D74 Methaemoglobinaemia	0.003	0.997	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.997	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.997	0.000
L43.8 Other lichen planus	0.002	0.997	0.000
L43.3 Subacute (active) lichen planus	0.002	0.997	0.000
L43.2 Lichenoid drug reaction	0.002	0.997	0.000
L43.1 Bullous lichen planus	0.002	0.997	0.000
L43.0 Hypertrophic lichen planus	0.002	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.997	0.000
D57 Sickle-cell disorders	0.002	0.997	0.000
D56 Thalassaemia	0.002	0.997	0.000
D55 Anaemia due to enzyme disorders	0.002	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.997	0.000
H74.1 Adhesive middle ear disease	0.002	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.002	0.997	0.000
Z96.6 Presence of orthopaedic joint implants	0.003	0.997	0.000
D73 Diseases of spleen	0.003	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.002
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.997	0.002
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.997	0.000
H71 Cholesteatoma of middle ear	0.002	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.997	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.997	0.000
D51.2 Transcobalamin II deficiency	0.002	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.002	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.002
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
H93.9 Disorder of ear, unspecified	0.002	0.997	0.000
H93.8 Other specified disorders of ear	0.002	0.997	0.000
H93.3 Disorders of acoustic nerve	0.002	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.997	0.000
D86 Sarcoidosis	0.002	0.997	0.000
D76.3 Other histiocytosis syndromes	0.002	0.997	0.000
M22.1 Recurrent subluxation of patella	0.002	0.997	0.000
M22.9 Disorder of patella, unspecified	0.002	0.997	0.000
M22.3 Other derangements of patella	0.002	0.997	0.000
M22.0 Recurrent dislocation of patella	0.002	0.997	0.000
M25.4 Effusion of joint	0.002	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
Z60.2 Living alone	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
M20-M25 Other joint disorders	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.001
M23.1 Discoid meniscus (congenital)	0.002	0.998	0.000
M23.0 Cystic meniscus	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
H52.1 Myopia	0.002	0.998	0.000
M23.5 Chronic instability of knee	0.002	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
M23.4 Loose body in knee	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
M35.7 Hypermobility syndrome	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.998	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
M35 Other systemic involvement of connective tissue	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
D41.0 Kidney	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.002	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.00 Cystic meniscus (Multiple sites)	0.002	0.998	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.002	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.002	0.998	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.002	0.998	0.000
M33 Dermatopolymyositis	0.002	0.998	0.000
M32 Systemic lupus erythematosus	0.002	0.998	0.000
M30 Polyarteritis nodosa and related conditions	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.002	0.998	0.000
M75.0 Adhesive capsulitis of shoulder	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.998	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.998	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
M24.1 Other articular cartilage disorders	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations