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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8098701
log Bayes Factor = 1.45811
Chromosome 18   position 43,551,013  (GRCh37) Explore rs8098701 on Ensembl!
Variant rs8098701 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M20-M25 Other joint disorders
0.965 0.035 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.964 0.036 0.000
M80-M85 Disorders of bone density and structure
0.956 0.044 0.000
M25 Other joint disorders, not elsewhere classified
0.954 0.046 0.000
M23 Internal derangement of knee
0.936 0.064 0.000
M84 Disorders of continuity of bone
0.936 0.064 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.930 0.070 0.000
M25.8 Other specified joint disorders
0.925 0.075 0.000
M45-M49 Spondylopathies
0.923 0.077 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.917 0.083 0.000
M05-M14 Inflammatory polyarthropathies
0.911 0.089 0.000
M47 Spondylosis
0.900 0.100 0.000
M21 Other acquired deformities of limbs
0.899 0.101 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.897 0.103 0.000
M47.8 Other spondylosis
0.888 0.112 0.000
M35 Other systemic involvement of connective tissue
0.878 0.122 0.000
M40-M43 Deforming dorsopathies
0.876 0.124 0.000
M85 Other disorders of bone density and structure
0.876 0.124 0.000
M86-M90 Other osteopathies
0.868 0.132 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.853 0.147 0.000
M11 Other crystal arthropathies
0.850 0.150 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.843 0.157 0.000
M00-M03 Infectious arthropathies
0.839 0.161 0.000
M47.89 Other spondylosis (Site unspecified)
0.838 0.162 0.000
M25.4 Effusion of joint
0.833 0.167 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.828 0.172 0.000
M13 Other arthritis
0.819 0.181 0.000
M84.0 Malunion of fracture
0.816 0.184 0.000
M25.7 Osteophyte
0.815 0.185 0.000
M35.0 Sicca syndrome [Sjogren]
0.812 0.188 0.000
M11.2 Other chondrocalcinosis
0.806 0.194 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.794 0.206 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.787 0.213 0.000
M43 Other deforming dorsopathies
0.775 0.225 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.775 0.225 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.770 0.230 0.000
M47.82 Other spondylosis (Cervical region)
0.770 0.230 0.000
M25.77 Osteophyte (Ankle and foot)
0.767 0.233 0.000
M89 Other disorders of bone
0.764 0.236 0.000
M25.86 Other specified joint disorders (Lower leg)
0.763 0.237 0.000
M13.9 Arthritis, unspecified
0.757 0.243 0.000
M82 Osteoporosis in diseases classified elsewhere
0.755 0.245 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.754 0.246 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.751 0.249 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.750 0.250 0.000
M00 Pyogenic arthritis
0.750 0.250 0.000
M85.8 Other specified disorders of bone density and structure
0.748 0.252 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
M23.4 Loose body in knee
0.743 0.257 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.737 0.263 0.000
M21.3 Wrist or foot drop (acquired)
0.737 0.263 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.736 0.264 0.000
M21.2 Flexion deformity
0.736 0.264 0.000
M86 Osteomyelitis
0.735 0.265 0.000
M25.84 Other specified joint disorders (Hand)
0.733 0.267 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.733 0.267 0.000
M30 Polyarteritis nodosa and related conditions
0.731 0.269 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.726 0.274 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.726 0.274 0.000
M14 Arthropathies in other diseases classified elsewhere
0.726 0.274 0.000
M84.4 Pathological fracture, not elsewhere classified
0.725 0.275 0.000
M22 Disorders of patella
0.718 0.282 0.000
M21.0 Valgus deformity, not elsewhere classified
0.717 0.283 0.000
M23.0 Cystic meniscus
0.716 0.284 0.000
M25.88 Other specified joint disorders (Other)
0.715 0.285 0.000
M85.9 Disorder of bone density and structure, unspecified
0.715 0.285 0.000
M35.1 Other overlap syndromes
0.714 0.286 0.000
M43.1 Spondylolisthesis
0.713 0.287 0.000
M21.1 Varus deformity, not elsewhere classified
0.711 0.289 0.000
M47.9 Spondylosis, unspecified
0.706 0.294 0.000
M85.0 Fibrous dysplasia (monostotic)
0.702 0.298 0.000
M25.0 Haemarthrosis
0.701 0.299 0.000
M41 Scoliosis
0.700 0.299 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.696 0.304 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.695 0.305 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.694 0.305 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.693 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M00.9 Pyogenic arthritis, unspecified
0.686 0.314 0.000
M83 Adult osteomalacia
0.685 0.315 0.000
M25.2 Flail joint
0.684 0.316 0.000
M25.1 Fistula of joint
0.684 0.316 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.683 0.317 0.000
M48 Other spondylopathies
0.682 0.318 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.680 0.320 0.000
M35.7 Hypermobility syndrome
0.676 0.324 0.000
M89.8 Other specified disorders of bone
0.674 0.326 0.000
M23.9 Internal derangement of knee, unspecified
0.674 0.326 0.000
M60-M63 Disorders of muscles
0.673 0.327 0.000
M47.1 Other spondylosis with myelopathy
0.673 0.327 0.000
M23.1 Discoid meniscus (congenital)
0.671 0.329 0.000
M84.9 Disorder of continuity of bone, unspecified
0.671 0.329 0.000
M84.8 Other disorders of continuity of bone
0.671 0.329 0.000
M84.3 Stress fracture, not elsewhere classified
0.671 0.329 0.000
M84.2 Delayed union of fracture
0.671 0.329 0.000
M25.46 Effusion of joint (Lower leg)
0.671 0.329 0.000
M25.3 Other instability of joint
0.670 0.330 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.669 0.331 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.666 0.333 0.000
M84.02 Malunion of fracture (Upper arm)
0.664 0.336 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.663 0.337 0.000
M25.83 Other specified joint disorders (Forearm)
0.663 0.337 0.000
M25.82 Other specified joint disorders (Upper arm)
0.663 0.337 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.663 0.337 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.338 0.000
M40 Kyphosis and lordosis
0.660 0.340 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.657 0.343 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.654 0.346 0.000
M12 Other specific arthropathies
0.653 0.346 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.653 0.346 0.000
M08 Juvenile arthritis
0.653 0.346 0.000
M25.78 Osteophyte (Other)
0.653 0.347 0.000
M45 Ankylosing spondylitis
0.652 0.348 0.000
M80 Osteoporosis with pathological fracture
0.650 0.349 0.000
M47.86 Other spondylosis (Lumbar region)
0.647 0.353 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.645 0.354 0.000
M21.9 Acquired deformity of limb, unspecified
0.644 0.356 0.000
M21.8 Other specified acquired deformities of limbs
0.644 0.356 0.000
M21.7 Unequal limb length (acquired)
0.644 0.356 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.643 0.357 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.643 0.357 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.642 0.358 0.000
M86.9 Osteomyelitis, unspecified
0.640 0.360 0.000
M88 Paget's disease of bone [osteitis deformans]
0.637 0.363 0.000
M25.47 Effusion of joint (Ankle and foot)
0.637 0.363 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.637 0.363 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.637 0.363 0.000
M47.84 Other spondylosis (Thoracic region)
0.637 0.363 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.637 0.363 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.637 0.363 0.000
M23.5 Chronic instability of knee
0.637 0.363 0.000
M34 Systemic sclerosis
0.633 0.367 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.633 0.367 0.000
M25.9 Joint disorder, unspecified
0.632 0.368 0.000
M85.6 Other cyst of bone
0.632 0.368 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.630 0.370 0.000
M35.8 Other specified systemic involvement of connective tissue
0.630 0.370 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.630 0.370 0.000
M35.5 Multifocal fibrosclerosis
0.630 0.370 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.630 0.370 0.000
M35.2 Behcet's disease
0.630 0.370 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.629 0.371 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.629 0.371 0.000
M42 Spinal osteochondrosis
0.628 0.371 0.000
M07 Psoriatic and enteropathic arthropathies
0.628 0.372 0.000
M85.5 Aneurysmal bone cyst
0.628 0.372 0.000
M85.4 Solitary bone cyst
0.628 0.372 0.000
M85.3 Osteitis condensans
0.628 0.372 0.000
M85.2 Hyperostosis of skull
0.628 0.372 0.000
M85.1 Skeletal fluorosis
0.628 0.372 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.621 0.379 0.000
M05 Seropositive rheumatoid arthritis
0.620 0.379 0.000
M81 Osteoporosis without pathological fracture
0.620 0.380 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.620 0.380 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.619 0.380 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.619 0.381 0.000
M22.8 Other disorders of patella
0.618 0.382 0.000
M82.1 Osteoporosis in endocrine disorders
0.611 0.389 0.000
M90 Osteopathies in diseases classified elsewhere
0.611 0.389 0.000
M11.9 Crystal arthropathy, unspecified
0.609 0.390 0.000
M11.8 Other specified crystal arthropathies
0.609 0.390 0.000
M11.1 Familial chondrocalcinosis
0.609 0.390 0.000
M11.0 Hydroxyapatite deposition disease
0.609 0.390 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.608 0.392 0.000
M10 Gout
0.607 0.393 0.000
M23.49 Loose body in knee-Unspec lig/men
0.605 0.395 0.000
M21.26 Flexion deformity (Lower leg)
0.604 0.396 0.000
M21.4 Flat foot [pes planus] (acquired)
0.604 0.396 0.000
M21.6 Other acquired deformities of ankle and foot
0.602 0.398 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.602 0.398 0.000
M02 Reactive arthropathies
0.602 0.398 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.602 0.398 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.599 0.401 0.000
M25.74 Osteophyte (Hand)
0.598 0.402 0.000
M13.94 Arthritis, unspecified (Hand)
0.598 0.402 0.000
M25.71 Osteophyte (Shoulder region)
0.598 0.402 0.000
M25.49 Effusion of joint (Site unspecified)
0.598 0.402 0.000
M25.48 Effusion of joint (Other)
0.598 0.402 0.000
M25.44 Effusion of joint (Hand)
0.598 0.402 0.000
M25.43 Effusion of joint (Forearm)
0.598 0.402 0.000
M25.42 Effusion of joint (Upper arm)
0.598 0.402 0.000
M25.41 Effusion of joint (Shoulder region)
0.598 0.402 0.000
M25.40 Effusion of joint (Multiple sites)
0.598 0.402 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.596 0.404 0.000
M14.6 Neuropathic arthropathy
0.593 0.407 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.589 0.411 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.588 0.412 0.000
M13.8 Other specified arthritis
0.587 0.413 0.000
M13.1 Monoarthritis, not elsewhere classified
0.587 0.413 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.587 0.413 0.000
M84.09 Malunion of fracture (Site unspecified)
0.585 0.415 0.000
M84.08 Malunion of fracture (Other)
0.585 0.415 0.000
M84.06 Malunion of fracture (Lower leg)
0.585 0.415 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.585 0.415 0.000
M84.04 Malunion of fracture (Hand)
0.585 0.415 0.000
M84.01 Malunion of fracture (Shoulder region)
0.585 0.415 0.000
M84.00 Malunion of fracture (Multiple sites)
0.585 0.415 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.585 0.415 0.000
M89.5 Osteolysis
0.585 0.415 0.000
M25.79 Osteophyte (Site unspecified)
0.584 0.416 0.000
M25.73 Osteophyte (Forearm)
0.584 0.416 0.000
M25.70 Osteophyte (Multiple sites)
0.584 0.416 0.000
M21.24 Flexion deformity (Hand)
0.583 0.417 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.581 0.419 0.000
M46 Other inflammatory spondylopathies
0.580 0.420 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.578 0.422 0.000
M11.28 Other chondrocalcinosis (Other)
0.578 0.422 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.578 0.422 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.578 0.422 0.000
M11.24 Other chondrocalcinosis (Hand)
0.578 0.422 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.578 0.422 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.578 0.422 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.578 0.422 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.578 0.422 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.578 0.422 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.578 0.422 0.000
M89.3 Hypertrophy of bone
0.577 0.423 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.577 0.423 0.000
M41.9 Scoliosis, unspecified
0.574 0.426 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.574 0.426 0.000
M13.0 Polyarthritis, unspecified
0.572 0.428 0.000
M24 Other specific joint derangements
0.570 0.429 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.570 0.430 0.000
M94 Other disorders of cartilage
0.569 0.430 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.569 0.431 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.569 0.431 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.569 0.431 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.569 0.431 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.569 0.431 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.569 0.431 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.569 0.431 0.000
M84.03 Malunion of fracture (Forearm)
0.567 0.433 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.564 0.436 0.000
M93 Other osteochondropathies
0.561 0.439 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.561 0.439 0.000
M13.93 Arthritis, unspecified (Forearm)
0.560 0.440 0.000
M87 Osteonecrosis
0.559 0.441 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.558 0.442 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.558 0.442 0.000
M43.9 Deforming dorsopathy, unspecified
0.556 0.444 0.000
M43.8 Other specified deforming dorsopathies
0.556 0.444 0.000
M43.6 Torticollis
0.556 0.444 0.000
M43.5 Other recurrent vertebral subluxation
0.556 0.444 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.556 0.444 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.556 0.444 0.000
M43.2 Other fusion of spine
0.556 0.444 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.551 0.449 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.550 0.449 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.550 0.449 0.000
M25.72 Osteophyte (Upper arm)
0.549 0.451 0.000
M89.6 Osteopathy after poliomyelitis
0.548 0.452 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.548 0.452 0.000
M89.2 Other disorders of bone development and growth
0.548 0.452 0.000
M89.1 Epiphyseal arrest
0.548 0.452 0.000
M89.0 Algoneurodystrophy
0.548 0.452 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.543 0.457 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.541 0.459 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.541 0.459 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.541 0.459 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.538 0.462 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.538 0.462 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.538 0.462 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.538 0.462 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.537 0.463 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.537 0.463 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.537 0.463 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.537 0.463 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.537 0.463 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.537 0.463 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.537 0.463 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.537 0.463 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.537 0.463 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.536 0.464 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.535 0.465 0.000
M92 Other juvenile osteochondrosis
0.534 0.465 0.000
M23.47 Loose body in knee-Capsular lig
0.533 0.467 0.000
M23.46 Loose body in knee-O/unsp lat men
0.533 0.467 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.533 0.467 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.533 0.467 0.000
M23.43 Loose body in knee-Med lig/oth men
0.533 0.467 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.533 0.467 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.533 0.467 0.000
M23.40 Loose body in knee-Mult sites
0.533 0.467 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.532 0.468 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.528 0.472 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.528 0.472 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.528 0.472 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.528 0.472 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.528 0.472 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.528 0.472 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.528 0.472 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.528 0.472 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.528 0.472 0.000
M21.29 Flexion deformity (Site unspecified)
0.528 0.472 0.000
M21.28 Flexion deformity (Other)
0.528 0.472 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.528 0.472 0.000
M21.23 Flexion deformity (Forearm)
0.528 0.472 0.000
M21.22 Flexion deformity (Upper arm)
0.528 0.472 0.000
M21.21 Flexion deformity (Shoulder region)
0.528 0.472 0.000
M21.20 Flexion deformity (Multiple sites)
0.528 0.472 0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.528 0.472 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.528 0.472 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.528 0.472 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.528 0.472 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.528 0.472 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.528 0.472 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.528 0.472 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.528 0.472 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.528 0.472 0.000
M86.8 Other osteomyelitis
0.527 0.473 0.000
M86.6 Other chronic osteomyelitis
0.527 0.473 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.527 0.473 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.527 0.473 0.000
M86.3 Chronic multifocal osteomyelitis
0.527 0.473 0.000
M86.2 Subacute osteomyelitis
0.527 0.473 0.000
M86.1 Other acute osteomyelitis
0.527 0.473 0.000
M86.0 Acute haematogenous osteomyelitis
0.527 0.473 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.526 0.474 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.524 0.475 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.524 0.475 0.000
M30.2 Juvenile polyarteritis
0.524 0.475 0.000
M30.0 Polyarteritis nodosa
0.524 0.475 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.522 0.478 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.520 0.479 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.520 0.479 0.000
M14.4 Arthropathy in amyloidosis
0.520 0.479 0.000
M14.3 Lipoid dermatoarthritis
0.520 0.479 0.000
M14.2 Diabetic arthropathy
0.520 0.479 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.520 0.479 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.520 0.479 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.520 0.480 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.520 0.480 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.520 0.480 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.520 0.480 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.520 0.480 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.520 0.480 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.520 0.480 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.520 0.480 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.520 0.480 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.520 0.480 0.000
M43.0 Spondylolysis
0.519 0.481 0.000
M25.06 Haemarthrosis (Lower leg)
0.519 0.481 0.000
M81.4 Drug-induced osteoporosis
0.517 0.483 0.000
M89.9 Disorder of bone, unspecified
0.515 0.485 0.000
M22.1 Recurrent subluxation of patella
0.515 0.485 0.000
M22.9 Disorder of patella, unspecified
0.515 0.485 0.000
M22.0 Recurrent dislocation of patella
0.515 0.485 0.000
M48.0 Spinal stenosis
0.514 0.486 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.514 0.486 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.514 0.486 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.514 0.486 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.514 0.486 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.514 0.486 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.514 0.486 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.514 0.486 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.514 0.486 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.513 0.486 0.000
M23.07 Cystic meniscus-Capsular lig
0.513 0.486 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.513 0.486 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.513 0.486 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.513 0.486 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.513 0.486 0.000
M23.00 Cystic meniscus (Multiple sites)
0.513 0.486 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.512 0.487 0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.512 0.487 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.512 0.487 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.512 0.487 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.512 0.487 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.512 0.487 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.512 0.487 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.512 0.487 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.512 0.487 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.511 0.489 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.511 0.489 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.511 0.489 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.511 0.489 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.511 0.489 0.000
M43.12 Spondylolisthesis (Cervical region)
0.511 0.489 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.511 0.489 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.511 0.489 0.000
M25.5 Pain in joint
0.510 0.490 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.510 0.490 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.509 0.490 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.509 0.490 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.509 0.490 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.509 0.490 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.509 0.490 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.509 0.490 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.509 0.490 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.509 0.490 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.507 0.492 0.000
M89.88 Other specified disorders of bone (Other)
0.507 0.493 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.506 0.494 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.506 0.494 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.506 0.494 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.506 0.494 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.506 0.494 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.506 0.494 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.505 0.495 0.000
M40.2 Other and unspecified kyphosis
0.505 0.495 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.503 0.496 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.503 0.496 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.503 0.496 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.503 0.496 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.503 0.496 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.503 0.496 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.503 0.496 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.503 0.496 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.503 0.496 0.000
M25.09 Haemarthrosis (Site unspecified)
0.502 0.497 0.000
M25.08 Haemarthrosis (Other)
0.502 0.497 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.502 0.497 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.502 0.497 0.000
M25.04 Haemarthrosis (Hand)
0.502 0.497 0.000
M25.03 Haemarthrosis (Forearm)
0.502 0.497 0.000
M25.02 Haemarthrosis (Upper arm)
0.502 0.497 0.000
M25.01 Haemarthrosis (Shoulder region)
0.502 0.497 0.000
M25.00 Haemarthrosis (Multiple sites)
0.502 0.497 0.000
M41.8 Other forms of scoliosis
0.502 0.498 0.000
M41.5 Other secondary scoliosis
0.502 0.498 0.000
M41.4 Neuromuscular scoliosis
0.502 0.498 0.000
M41.3 Thoracogenic scoliosis
0.502 0.498 0.000
M41.2 Other idiopathic scoliosis
0.502 0.498 0.000
M41.1 Juvenile idiopathic scoliosis
0.502 0.498 0.000
M41.0 Infantile idiopathic scoliosis
0.502 0.498 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.502 0.498 0.000
M22.4 Chondromalacia patellae
0.502 0.498 0.000
M25.37 Other instability of joint (Ankle and foot)
0.498 0.502 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.497 0.503 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.497 0.503 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.497 0.503 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.497 0.503 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.497 0.503 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.497 0.503 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.497 0.503 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.497 0.503 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.497 0.503 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.496 0.504 0.000
M32.8 Other forms of systemic lupus erythematosus
0.496 0.504 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.496 0.504 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.496 0.504 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.496 0.504 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.496 0.504 0.000
M36.3 Arthropathy in other blood disorders
0.496 0.504 0.000
M36.2 Haemophilic arthropathy
0.496 0.504 0.000
M36.1 Arthropathy in neoplastic disease
0.496 0.504 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.496 0.504 0.000
M33.9 Dermatopolymyositis, unspecified
0.496 0.504 0.000
M33.2 Polymyositis
0.496 0.504 0.000
M33.0 Juvenile dermatomyositis
0.496 0.504 0.000
M33.1 Other dermatomyositis
0.496 0.504 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.496 0.504 0.000
M06 Other rheumatoid arthritis
0.493 0.507 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.492 0.508 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.492 0.508 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.492 0.508 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.492 0.508 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.492 0.508 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.492 0.508 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.492 0.508 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.492 0.508 0.000
M83.9 Adult osteomalacia, unspecified
0.491 0.509 0.000
M83.8 Other adult osteomalacia
0.491 0.509 0.000
M83.5 Other drug-induced osteomalacia in adults
0.491 0.509 0.000
M83.4 Aluminum bone disease
0.491 0.509 0.000
M83.3 Adult osteomalacia due to malnutrition
0.491 0.509 0.000
M83.2 Adult osteomalacia due to malabsorption
0.491 0.509 0.000
M83.1 Senile osteomalacia
0.491 0.509 0.000
M83.0 Puerperal osteomalacia
0.491 0.509 0.000
M25.19 Fistula of joint (Site unspecified)
0.491 0.509 0.000
M25.18 Fistula of joint (Other)
0.491 0.509 0.000
M25.17 Fistula of joint (Ankle and foot)
0.491 0.509 0.000
M25.16 Fistula of joint (Lower leg)
0.491 0.509 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.491 0.509 0.000
M25.14 Fistula of joint (Hand)
0.491 0.509 0.000
M25.13 Fistula of joint (Forearm)
0.491 0.509 0.000
M25.12 Fistula of joint (Upper arm)
0.491 0.509 0.000
M25.11 Fistula of joint (Shoulder region)
0.491 0.509 0.000
M25.10 Fistula of joint (Multiple sites)
0.491 0.509 0.000
M25.29 Flail joint (Site unspecified)
0.491 0.509 0.000
M25.28 Flail joint (Other)
0.491 0.509 0.000
M25.27 Flail joint (Ankle and foot)
0.491 0.509 0.000
M25.26 Flail joint (Lower leg)
0.491 0.509 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.491 0.509 0.000
M25.24 Flail joint (Hand)
0.491 0.509 0.000
M25.23 Flail joint (Forearm)
0.491 0.509 0.000
M25.22 Flail joint (Upper arm)
0.491 0.509 0.000
M25.21 Flail joint (Shoulder region)
0.491 0.509 0.000
M25.20 Flail joint (Multiple sites)
0.491 0.509 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.489 0.510 0.000
M48.9 Spondylopathy, unspecified
0.489 0.511 0.000
M48.8 Other specified spondylopathies
0.489 0.511 0.000
M48.4 Fatigue fracture of vertebra
0.489 0.511 0.000
M48.3 Traumatic spondylopathy
0.489 0.511 0.000
M48.2 Kissing spine
0.489 0.511 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.489 0.511 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.488 0.512 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.486 0.514 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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