TreeWAS – Variant ID: rs8099213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H72 Perforation of tympanic membrane	0.774	0.226	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.765	0.235	0.000
H65-H75 Diseases of middle ear and mastoid	0.761	0.239	0.000
H66 Suppurative and unspecified otitis media	0.760	0.240	0.000
H66.9 Otitis media, unspecified	0.759	0.241	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.724	0.276	0.000
H72.8 Other perforations of tympanic membrane	0.716	0.284	0.000
H72.1 Attic perforation of tympanic membrane	0.689	0.311	0.000
H71 Cholesteatoma of middle ear	0.686	0.314	0.000
H73 Other disorders of tympanic membrane	0.670	0.330	0.000
H72.0 Central perforation of tympanic membrane	0.666	0.334	0.000
H72.2 Other marginal perforations of tympanic membrane	0.565	0.435	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.561	0.439	0.000
H68 Eustachian salpingitis and obstruction	0.559	0.441	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.546	0.454	0.000
H67 Otitis media in diseases classified elsewhere	0.546	0.454	0.000
H66.0 Acute suppurative otitis media	0.539	0.461	0.000
H70 Mastoiditis and related conditions	0.534	0.465	0.000
H73.1 Chronic myringitis	0.533	0.467	0.000
H73.0 Acute myringitis	0.501	0.499	0.000
H73.8 Other specified disorders of tympanic membrane	0.493	0.507	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.493	0.507	0.000
H65 Nonsuppurative otitis media	0.448	0.552	0.000
H66.4 Suppurative otitis media, unspecified	0.440	0.559	0.000
H70.1 Chronic mastoiditis	0.418	0.582	0.000
H68.1 Obstruction of Eustachian tube	0.415	0.585	0.000
H68.0 Eustachian salpingitis	0.401	0.599	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.391	0.609	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.391	0.609	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.391	0.609	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.391	0.609	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.391	0.609	0.000
H70.2 Petrositis	0.383	0.617	0.000
H70.0 Acute mastoiditis	0.383	0.617	0.000
H70.8 Other mastoiditis and related conditions	0.383	0.617	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.370	0.630	0.000
H74 Other disorders of middle ear and mastoid	0.351	0.649	0.000
H69 Other disorders of Eustachian tube	0.347	0.652	0.000
H65.4 Other chronic nonsuppurative otitis media	0.342	0.658	0.000
H70.9 Mastoiditis, unspecified	0.324	0.676	0.000
H65.3 Chronic mucoid otitis media	0.318	0.682	0.000
H74.0 Tympanosclerosis	0.308	0.692	0.000
H65.1 Other acute nonsuppurative otitis media	0.307	0.693	0.000
H65.0 Acute serous otitis media	0.279	0.721	0.000
H74.1 Adhesive middle ear disease	0.256	0.744	0.000
H69.0 Patulous Eustachian tube	0.249	0.751	0.000
H66.3 Other chronic suppurative otitis media	0.247	0.753	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.225	0.775	0.000
H69.8 Other specified disorders of Eustachian tube	0.223	0.777	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.217	0.782	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.213	0.787	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.193	0.807	0.000
H74.4 Polyp of middle ear	0.166	0.834	0.000
H65.2 Chronic serous otitis media	0.161	0.838	0.001
H69.9 Eustachian tube disorder, unspecified	0.113	0.886	0.001
G81.9 Hemiplegia, unspecified	0.060	0.940	0.000
G81 Hemiplegia	0.040	0.960	0.000
Chapter VIII Diseases of the ear and mastoid process	0.036	0.964	0.000
G81.1 Spastic hemiplegia	0.033	0.967	0.000
G81.0 Flaccid hemiplegia	0.029	0.971	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.017	0.983	0.000
G80 Infantile cerebral palsy	0.015	0.985	0.000
H80-H83 Diseases of inner ear	0.015	0.985	0.000
G80.9 Infantile cerebral palsy, unspecified	0.013	0.987	0.000
H60-H62 Diseases of external ear	0.012	0.988	0.000
G80.8 Other infantile cerebral palsy	0.012	0.988	0.000
G80.2 Infantile hemiplegia	0.011	0.989	0.000
G80.0 Spastic cerebral palsy	0.011	0.989	0.000
G80.4 Ataxic cerebral palsy	0.011	0.989	0.000
G80.3 Dyskinetic cerebral palsy	0.011	0.989	0.000
G80.1 Spastic diplegia	0.011	0.989	0.000
G83 Other paralytic syndromes	0.011	0.989	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.011	0.989	0.000
M54.36 Sciatica (Lumbar region)	0.011	0.989	0.000
H80 Otosclerosis	0.010	0.990	0.000
R47.0 Dysphasia and aphasia	0.009	0.991	0.000
H83 Other diseases of inner ear	0.009	0.991	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.009	0.991	0.000
G83.1 Monoplegia of lower limb	0.009	0.991	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.991	0.009
G82 Paraplegia and tetraplegia	0.009	0.991	0.000
G83.9 Paralytic syndrome, unspecified	0.008	0.991	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.008	0.992	0.000
G83.5 Locked-in syndrome	0.008	0.992	0.000
G83.3 Monoplegia, unspecified	0.008	0.992	0.000
G83.0 Diplegia of upper limbs	0.008	0.992	0.000
R47 Speech disturbances, not elsewhere classified	0.008	0.992	0.000
G83.2 Monoplegia of upper limb	0.008	0.992	0.000
R47.8 Other and unspecified speech disturbances	0.008	0.992	0.000
H80.8 Other otosclerosis	0.007	0.992	0.000
H80.2 Cochlear otosclerosis	0.007	0.992	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.007	0.992	0.000
H83.3 Noise effects on inner ear	0.007	0.993	0.000
H90-H95 Other disorders of ear	0.007	0.993	0.000
R47.1 Dysarthria and anarthria	0.007	0.993	0.000
H83.2 Labyrinthine dysfunction	0.007	0.993	0.000
H83.1 Labyrinthine fistula	0.007	0.993	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.007	0.993	0.000
G83.8 Other specified paralytic syndromes	0.007	0.993	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.007	0.993	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.007	0.993	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
H62.2 Otitis externa in mycoses	0.007	0.993	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.007	0.993	0.000
G82.4 Spastic tetraplegia	0.007	0.993	0.000
H83.0 Labyrinthitis	0.007	0.993	0.000
G83.4 Cauda equina syndrome	0.006	0.993	0.000
G82.5 Tetraplegia, unspecified	0.006	0.993	0.000
G82.3 Flaccid tetraplegia	0.006	0.994	0.000
G82.0 Flaccid paraplegia	0.006	0.994	0.000
I86.1 Scrotal varices	0.000	0.994	0.006
H83.9 Disease of inner ear, unspecified	0.006	0.994	0.000
H83.8 Other specified diseases of inner ear	0.006	0.994	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.006	0.994	0.000
I86.4 Gastric varices	0.000	0.994	0.006
H27.0 Aphakia	0.006	0.994	0.000
G82.1 Spastic paraplegia	0.005	0.994	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.005	0.995	0.000
M25.53 Pain in joint (Forearm)	0.005	0.995	0.000
I86 Varicose veins of other sites	0.000	0.995	0.005
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
D07.5 Prostate	0.000	0.995	0.005
C71.9 Brain, unspecified	0.005	0.995	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.005	0.995	0.000
I86.8 Varicose veins of other specified sites	0.000	0.995	0.005
H95.1 Other disorders following mastoidectomy	0.005	0.995	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.005	0.995	0.000
C71.4 Occipital lobe	0.005	0.995	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.004	0.996	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.996	0.004
H11.3 Conjunctival haemorrhage	0.000	0.996	0.004
C71.1 Frontal lobe	0.004	0.996	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H81 Disorders of vestibular function	0.004	0.996	0.000
I86.3 Vulval varices	0.000	0.996	0.004
I86.0 Sublingual varices	0.000	0.996	0.004
M13.96 Arthritis, unspecified (Lower leg)	0.004	0.996	0.000
C71.3 Parietal lobe	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.996	0.004
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
C71.2 Temporal lobe	0.004	0.996	0.000
H61 Other disorders of external ear	0.004	0.996	0.000
C71.7 Brain stem	0.004	0.996	0.000
C71.6 Cerebellum	0.004	0.996	0.000
C71.5 Cerebral ventricle	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.003	0.996	0.000
H60.0 Abscess of external ear	0.003	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.003	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
I86.2 Pelvic varices	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.000	0.997	0.003
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
R41.0 Disorientation, unspecified	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
N84.2 Polyp of vagina	0.000	0.997	0.003
H60.8 Other otitis externa	0.003	0.997	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
H81.8 Other disorders of vestibular function	0.003	0.997	0.000
H81.4 Vertigo of central origin	0.003	0.997	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.997	0.003
H47.3 Other disorders of optic disk	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.997	0.003
H61.2 Impacted cerumen	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.002	0.997	0.000
Z01.6 Radiological examination, not elsewhere classified	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.003	0.997	0.000
H27 Other disorders of lens	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.000	0.997	0.003
M54.64 Pain in thoracic spine (Thoracic region)	0.003	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.003	0.997	0.000
M22.8 Other disorders of patella	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
H81.3 Other peripheral vertigo	0.002	0.997	0.000
H81.0 Meniere's disease	0.003	0.997	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.997	0.002
H27.1 Dislocation of lens	0.003	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
M25.8 Other specified joint disorders	0.003	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.997	0.000
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.998	0.002
C72.0 Spinal cord	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002
J98.4 Other disorders of lung	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
H27.9 Disorder of lens, unspecified	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
C72.9 Central nervous system, unspecified	0.002	0.998	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.998	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.998	0.000
C72.4 Acoustic nerve	0.002	0.998	0.000
C72.3 Optic nerve	0.002	0.998	0.000
C72.2 Olfactory nerve	0.002	0.998	0.000
C72.1 Cauda equina	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
S63.5 Sprain and strain of wrist	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.998	0.002
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.002	0.998	0.000
C70.1 Spinal meninges	0.002	0.998	0.000
J98 Other respiratory disorders	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
C70.0 Cerebral meninges	0.002	0.998	0.000
K75.0 Abscess of liver	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
C02.2 Ventral surface of tongue	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M07.38 Other psoriatic arthropathies (Other)	0.000	0.998	0.002
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.998	0.002
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
J98.2 Interstitial emphysema	0.000	0.998	0.002
R48.0 Dyslexia and alexia	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
C02.8 Overlapping lesion of tongue	0.000	0.998	0.002
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.998	0.002
C02.0 Dorsal surface of tongue	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.002	0.998	0.000
R48.2 Apraxia	0.002	0.998	0.000
R48.1 Agnosia	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.998	0.002
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
Z72.8 Other problems related to lifestyle	0.000	0.998	0.002
H91.2 Sudden idiopathic hearing loss	0.001	0.998	0.000
C69.6 Orbit	0.001	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
S63.2 Multiple dislocations of fingers	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
J98.6 Disorders of diaphragm	0.000	0.998	0.002
L40.8 Other psoriasis	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
C02.4 Lingual tonsil	0.000	0.998	0.001
H27.8 Other specified disorders of lens	0.001	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
C69.0 Conjunctiva	0.001	0.998	0.000
J98.3 Compensatory emphysema	0.000	0.998	0.001
L40.4 Guttate psoriasis	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.001	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.001	0.998	0.000
C69.9 Eye, unspecified	0.001	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.001
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.002	0.998	0.000
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.001	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.001	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.000	0.998	0.001
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.999	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.999	0.001
M17.3 Other posttraumatic gonarthrosis	0.001	0.999	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.999	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.999	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.999	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.999	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.001	0.999	0.000
D03.5 Melanoma in situ of trunk	0.000	0.999	0.001
H46 Optic neuritis	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.001	0.999	0.000
S91.1 Open wound of toe(s) without damage to nail	0.001	0.999	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
N76.0 Acute vaginitis	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.001
C25.9 Pancreas, unspecified	0.000	0.999	0.001
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.999	0.001
M54.6 Pain in thoracic spine	0.001	0.999	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.999	0.001
L40.0 Psoriasis vulgaris	0.001	0.999	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.999	0.001
Z01.4 Gynaecological examination (general)(routine)	0.001	0.999	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.001	0.999	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
L89.1 Stage II decubitus ulcer	0.000	0.999	0.001
O41.0 Oligohydramnios	0.001	0.999	0.000
R41.1 Anterograde amnesia	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
M34.1 CR(E)ST syndrome	0.000	0.999	0.001
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
Z56.7 Other and unspecified problems related to employment	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
C25.3 Pancreatic duct	0.000	0.999	0.001
O21.9 Vomiting of pregnancy, unspecified	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
L40 Psoriasis	0.001	0.999	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
C50.1 Central portion of breast	0.000	0.999	0.001
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.999	0.001
O61.0 Failed medical induction of labour	0.001	0.999	0.000
R44.0 Auditory hallucinations	0.001	0.999	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.001	0.999	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.001	0.999	0.000
J98.1 Pulmonary collapse	0.000	0.999	0.001
M54.69 Pain in thoracic spine-Site unspe	0.001	0.999	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.999	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.999	0.000
M54.66 Pain in thoracic spine-Lumbar	0.001	0.999	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.999	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.999	0.000
M54.62 Pain in thoracic spine-Cervical	0.001	0.999	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.999	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.999	0.000
H57.8 Other specified disorders of eye and adnexa	0.001	0.999	0.000
C77.1 Intrathoracic lymph nodes	0.001	0.999	0.000
G30.0 Alzheimer's disease with early onset	0.001	0.999	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.001	0.999	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.001	0.999	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.001	0.999	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
Z01.8 Other specified special examinations	0.001	0.999	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
L40.3 Pustulosis palmaris et plantaris	0.001	0.999	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
Z97.8 Presence of other specified devices	0.000	0.999	0.001
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.001	0.999	0.000
H54.0 Blindness, both eyes	0.001	0.999	0.000
L40.2 Acrodermatitis continua	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
Q38.1 Ankyloglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
Z56.0 Unemployment, unspecified	0.001	0.999	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.999	0.001
S06.00 Concussion (without open intracranial wound)	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.999	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
O21 Excessive vomiting in pregnancy	0.001	0.999	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.999	0.001
H10.9 Conjunctivitis, unspecified	0.000	0.999	0.001
H54.2 Low vision, both eyes	0.001	0.999	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.999	0.001
O26.9 Pregnancy-related condition, unspecified	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
H11 Other disorders of conjunctiva	0.000	0.999	0.001
Z56 Problems related to employment and unemployment	0.001	0.999	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.999	0.001
H90.5 Sensorineural hearing loss, unspecified	0.001	0.999	0.001
K50.0 Crohn's disease of small intestine	0.001	0.999	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
Z01.0 Examination of eyes and vision	0.001	0.999	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.999	0.001
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.999	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
Z01.2 Dental examination	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
B34.8 Other viral infections of unspecified site	0.001	0.999	0.000
M15.1 Heberden's nodes (with arthropathy)	0.000	0.999	0.001
S27.0 Traumatic pneumothorax	0.001	0.999	0.000
Z01.1 Examination of ears and hearing	0.001	0.999	0.000
H54 Blindness and low vision	0.001	0.999	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.999	0.001
M89.3 Hypertrophy of bone	0.001	0.999	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
T31.0 Burns involving less than 10% of body surface	0.001	0.999	0.000
Z56.5 Uncongenial work	0.001	0.999	0.000
Z56.4 Discord with boss and workmates	0.001	0.999	0.000
Z56.2 Threat of job loss	0.001	0.999	0.000
Z56.1 Change of job	0.001	0.999	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.999	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M95.0 Acquired deformity of nose	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations