TreeWAS – Variant ID: rs8100241

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.000	0.837	0.163
C34 Malignant neoplasm of bronchus and lung	0.000	0.845	0.155
C34.1 Upper lobe, bronchus or lung	0.000	0.852	0.148
C34.2 Middle lobe, bronchus or lung	0.000	0.863	0.137
C34.3 Lower lobe, bronchus or lung	0.000	0.879	0.121
C34.8 Overlapping lesion of bronchus and lung	0.000	0.889	0.110
C34.0 Main bronchus	0.000	0.896	0.103
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.928	0.072
C32 Malignant neoplasm of larynx	0.000	0.934	0.066
C32.1 Supraglottis	0.000	0.939	0.061
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.948	0.052
C32.9 Larynx, unspecified	0.000	0.948	0.052
C31 Malignant neoplasm of accessory sinuses	0.000	0.948	0.052
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.951	0.049
C33 Malignant neoplasm of trachea	0.000	0.952	0.048
C32.0 Glottis	0.000	0.952	0.048
C32.8 Overlapping lesion of larynx	0.000	0.953	0.047
C32.3 Laryngeal cartilage	0.000	0.953	0.047
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.953	0.047
C37 Malignant neoplasm of thymus	0.000	0.955	0.045
K51.9 Ulcerative colitis, unspecified	0.043	0.957	0.000
C32.2 Subglottis	0.000	0.959	0.041
N48.4 Impotence of organic origin	0.000	0.961	0.039
C39.9 Ill-defined sites within the respiratory system	0.000	0.962	0.037
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.962	0.037
C39.0 Upper respiratory tract, part unspecified	0.000	0.962	0.037
C31.9 Accessory sinus, unspecified	0.000	0.962	0.037
C31.8 Overlapping lesion of accessory sinuses	0.000	0.962	0.037
C31.3 Sphenoidal sinus	0.000	0.962	0.037
C31.2 Frontal sinus	0.000	0.962	0.037
C31.1 Ethmoidal sinus	0.000	0.962	0.037
C31.0 Maxillary sinus	0.000	0.962	0.037
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.965	0.035
C38.2 Posterior mediastinum	0.000	0.965	0.035
C38.1 Anterior mediastinum	0.000	0.965	0.035
C38.0 Heart	0.000	0.965	0.035
C38.3 Mediastinum, part unspecified	0.000	0.965	0.035
C30.1 Middle ear	0.000	0.966	0.034
C38.4 Pleura	0.000	0.968	0.032
C30.0 Nasal cavity	0.000	0.971	0.029
E55.9 Vitamin D deficiency, unspecified	0.025	0.975	0.000
M22.4 Chondromalacia patellae	0.022	0.978	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.980	0.020
Q21.1 Atrial septal defect	0.018	0.982	0.000
C44.7 Skin of lower limb, including hip	0.000	0.983	0.017
C44.6 Skin of upper limb, including shoulder	0.000	0.983	0.017
Q21 Congenital malformations of cardiac septa	0.015	0.985	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.985	0.015
I49.9 Cardiac arrhythmia, unspecified	0.014	0.986	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.986	0.014
Q20-Q28 Congenital malformations of the circulatory system	0.013	0.987	0.000
C44 Other malignant neoplasms of skin	0.000	0.987	0.013
Q21.9 Congenital malformation of cardiac septum, unspecified	0.013	0.987	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.012	0.988	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.012	0.988	0.000
E55 Vitamin D deficiency	0.012	0.988	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.012	0.988	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.011	0.989	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.011	0.989	0.000
Q21.8 Other congenital malformations of cardiac septa	0.011	0.989	0.000
S64 Injury of nerves at wrist and hand level	0.011	0.989	0.000
Q63 Other congenital malformations of kidney	0.011	0.989	0.000
Q21.4 Aortopulmonary septal defect	0.011	0.989	0.000
Q21.2 Atrioventricular septal defect	0.011	0.989	0.000
Q21.3 Tetralogy of Fallot	0.011	0.989	0.000
Q76 Congenital malformations of spine and bony thorax	0.011	0.989	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.011	0.989	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.011	0.989	0.000
Q60-Q64 Congenital malformations of the urinary system	0.011	0.989	0.000
Q28 Other congenital malformations of circulatory system	0.011	0.989	0.000
Q63.0 Accessory kidney	0.010	0.989	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.990	0.010
S63.6 Sprain and strain of finger(s)	0.010	0.990	0.000
Q63.2 Ectopic kidney	0.010	0.990	0.000
Q25 Congenital malformations of great arteries	0.010	0.990	0.000
Q66 Congenital deformities of feet	0.010	0.990	0.000
S64.1 Injury of median nerve at wrist and hand level	0.010	0.990	0.000
Q26 Congenital malformations of great veins	0.010	0.990	0.000
S02.2 Fracture of nasal bones	0.000	0.990	0.010
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.010	0.990	0.000
Q23 Congenital malformations of aortic and mitral valves	0.010	0.990	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.010	0.990	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.010	0.990	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.010	0.990	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.009	0.990	0.000
K51 Ulcerative colitis	0.010	0.990	0.000
S63.0 Dislocation of wrist	0.009	0.990	0.000
C44.8 Overlapping lesion of skin	0.000	0.991	0.009
Q15 Other congenital malformations of eye	0.009	0.991	0.000
Q68 Other congenital musculoskeletal deformities	0.009	0.991	0.000
Q65 Congenital deformities of hip	0.009	0.991	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.009	0.991	0.000
Q18 Other congenital malformations of face and neck	0.009	0.991	0.000
Q12 Congenital lens malformations	0.009	0.991	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.009	0.991	0.000
Q74 Other congenital malformations of limb(s)	0.009	0.991	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.991	0.009
E55.0 Rickets, active	0.009	0.991	0.000
Q76.1 Klippel-Feil syndrome	0.009	0.991	0.000
Q67.6 Pectus excavatum	0.009	0.991	0.000
Q75 Other congenital malformations of skull and face bones	0.009	0.991	0.000
Q73 Reduction defects of unspecified limb	0.009	0.991	0.000
Q72 Reduction defects of lower limb	0.009	0.991	0.000
Q71 Reduction defects of upper limb	0.009	0.991	0.000
Q69 Polydactyly	0.009	0.991	0.000
Q66.6 Other congenital valgus deformities of feet	0.009	0.991	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.009	0.991	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.009	0.991	0.000
Q21.0 Ventricular septal defect	0.008	0.991	0.000
Q78 Other osteochondrodysplasias	0.008	0.991	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.008	0.991	0.000
Q70 Syndactyly	0.008	0.991	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.008	0.991	0.000
Q35-Q37 Cleft lip and cleft palate	0.008	0.991	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.008	0.992	0.000
Q63.8 Other specified congenital malformations of kidney	0.008	0.992	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.008	0.992	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.008	0.992	0.000
Q50-Q56 Congenital malformations of genital organs	0.008	0.992	0.000
Q60.0 Renal agenesis, unilateral	0.008	0.992	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.008	0.992	0.000
S64.8 Injury of other nerves at wrist and hand level	0.008	0.992	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.008	0.992	0.000
Q63.3 Hyperplastic and giant kidney	0.008	0.992	0.000
Q28.3 Other malformations of cerebral vessels	0.008	0.992	0.000
Q66.3 Other congenital varus deformities of feet	0.008	0.992	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.008	0.992	0.000
Q66.8 Other congenital deformities of feet	0.008	0.992	0.000
Q15.0 Congenital glaucoma	0.008	0.992	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.008	0.992	0.000
Q76.8 Other congenital malformations of bony thorax	0.008	0.992	0.000
Q76.7 Congenital malformation of sternum	0.008	0.992	0.000
Q76.6 Other congenital malformations of ribs	0.008	0.992	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.008	0.992	0.000
Q76.2 Congenital spondylolisthesis	0.008	0.992	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.008	0.992	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.008	0.992	0.000
Q17 Other congenital malformations of ear	0.008	0.992	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.008	0.992	0.000
Q13 Congenital malformations of anterior segment of eye	0.008	0.992	0.000
S63.1 Dislocation finger	0.008	0.992	0.000
S63.2 Multiple dislocations of fingers	0.008	0.992	0.000
Q24 Other congenital malformations of heart	0.008	0.992	0.000
Q23.0 Congenital stenosis of aortic valve	0.008	0.992	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.008	0.992	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.008	0.992	0.000
Q28.1 Other malformations of precerebral vessels	0.008	0.992	0.000
S63.5 Sprain and strain of wrist	0.008	0.992	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.008	0.992	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.008	0.992	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.008	0.992	0.000
C44.0 Skin of lip	0.000	0.992	0.008
Q14 Congenital malformations of posterior segment of eye	0.008	0.992	0.000
Q25.0 Patent ductus arteriosus	0.008	0.992	0.000
Q25.4 Other congenital malformations of aorta	0.008	0.992	0.000
Q12.0 Congenital cataract	0.008	0.992	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.008	0.992	0.000
Q64 Other congenital malformations of urinary system	0.008	0.992	0.000
Q66.0 Talipes equinovarus	0.008	0.992	0.000
Q74.1 Congenital malformation of knee	0.008	0.992	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.007	0.992	0.000
Q27 Other congenital malformations of peripheral vascular system	0.008	0.992	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.007	0.992	0.000
Q25.8 Other congenital malformations of great arteries	0.007	0.992	0.000
Q25.5 Atresia of pulmonary artery	0.007	0.992	0.000
Q25.2 Atresia of aorta	0.007	0.992	0.000
Q66.7 Pes cavus	0.007	0.992	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.008	0.992	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.007	0.992	0.000
Q60.3 Renal hypoplasia, unilateral	0.007	0.992	0.000
Q23.1 Congenital insufficiency of aortic valve	0.007	0.992	0.000
Q66.5 Congenital pes planus	0.007	0.993	0.000
Q66.4 Talipes calcaneovalgus	0.007	0.993	0.000
Q66.1 Talipes calcaneovarus	0.007	0.993	0.000
K52 Other non-infective gastro-enteritis and colitis	0.007	0.993	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.007	0.993	0.000
Q26.8 Other congenital malformations of great veins	0.007	0.993	0.000
Q26.6 Portal vein-hepatic artery fistula	0.007	0.993	0.000
Q26.5 Anomalous portal venous connexion	0.007	0.993	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.007	0.993	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.007	0.993	0.000
Q26.1 Persistent left superior vena cava	0.007	0.993	0.000
Q26.0 Congenital stenosis of vena cava	0.007	0.993	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.007	0.993	0.000
Q25.3 Stenosis of aorta	0.007	0.993	0.000
Q60.2 Renal agenesis, unspecified	0.007	0.993	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.007	0.993	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.007	0.993	0.000
Q23.4 Hypoplastic left heart syndrome	0.007	0.993	0.000
Q23.2 Congenital mitral stenosis	0.007	0.993	0.000
Q65.8 Other congenital deformities of hip	0.007	0.993	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.007	0.993	0.000
K51.8 Other ulcerative colitis	0.007	0.993	0.000
Q25.1 Coarctation of aorta	0.007	0.993	0.000
Q76.5 Cervical rib	0.007	0.993	0.000
Q25.6 Stenosis of pulmonary artery	0.007	0.993	0.000
Q96 Turner's syndrome	0.007	0.993	0.000
Q18.1 Preauricular sinus and cyst	0.007	0.993	0.000
Q67.8 Other congenital deformities of chest	0.007	0.993	0.000
Q67.7 Pectus carinatum	0.007	0.993	0.000
Q67.3 Plagiocephaly	0.007	0.993	0.000
Q67.2 Dolichocephaly	0.007	0.993	0.000
Q67.1 Compression facies	0.007	0.993	0.000
Q67.0 Facial asymmetry	0.007	0.993	0.000
Q60.6 Potter's syndrome	0.007	0.993	0.000
Q60.5 Renal hypoplasia, unspecified	0.007	0.993	0.000
Q60.4 Renal hypoplasia, bilateral	0.007	0.993	0.000
Q60.1 Renal agenesis, bilateral	0.007	0.993	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.007	0.993	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.007	0.993	0.000
Q20.6 Isomerism of atrial appendages	0.007	0.993	0.000
Q20.5 Discordant atrioventricular connexion	0.007	0.993	0.000
Q20.4 Double inlet ventricle	0.007	0.993	0.000
Q20.3 Discordant ventriculoarterial connexion	0.007	0.993	0.000
Q20.2 Double outlet left ventricle	0.007	0.993	0.000
Q20.1 Double outlet right ventricle	0.007	0.993	0.000
Q20.0 Common arterial trunk	0.007	0.993	0.000
Q67.5 Congenital deformity of spine	0.007	0.993	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.007	0.993	0.000
S60-S69 Injuries to the wrist and hand	0.007	0.993	0.000
Q66.2 Metatarsus varus	0.007	0.993	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.007	0.993	0.000
Q15.9 Congenital malformation of eye, unspecified	0.007	0.993	0.000
Q15.8 Other specified congenital malformations of eye	0.007	0.993	0.000
S64.4 Injury of digital nerve of other finger	0.007	0.993	0.000
Q80-Q89 Other congenital malformations	0.007	0.993	0.000
Q22.5 Ebstein's anomaly	0.007	0.993	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.007	0.993	0.000
Q68.4 Congenital bowing of tibia and fibula	0.007	0.993	0.000
Q68.3 Congenital bowing of femur	0.007	0.993	0.000
Q68.2 Congenital deformity of knee	0.007	0.993	0.000
Q68.1 Congenital deformity of hand	0.007	0.993	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.007	0.993	0.000
Q65.9 Congenital deformity of hip, unspecified	0.007	0.993	0.000
Q65.6 Unstable hip	0.007	0.993	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.007	0.993	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.007	0.993	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.007	0.993	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.007	0.993	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.007	0.993	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.007	0.993	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.007	0.993	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.007	0.993	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.007	0.993	0.000
Q22.6 Hypoplastic right heart syndrome	0.007	0.993	0.000
Q22.4 Congenital tricuspid stenosis	0.007	0.993	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.007	0.993	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.007	0.993	0.000
Q22.0 Pulmonary valve atresia	0.007	0.993	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.007	0.993	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.007	0.993	0.000
Q18.8 Other specified congenital malformations of face and neck	0.007	0.993	0.000
Q18.7 Microcheilia	0.007	0.993	0.000
Q18.6 Macrocheilia	0.007	0.993	0.000
Q18.5 Microstomia	0.007	0.993	0.000
Q18.4 Macrostomia	0.007	0.993	0.000
Q18.3 Webbing of neck	0.007	0.993	0.000
Q18.2 Other branchial cleft malformations	0.007	0.993	0.000
H80.9 Otosclerosis, unspecified	0.007	0.993	0.000
Q12.9 Congenital lens malformation, unspecified	0.007	0.993	0.000
Q12.8 Other congenital lens malformations	0.007	0.993	0.000
Q12.4 Spherophakia	0.007	0.993	0.000
Q12.3 Congenital aphakia	0.007	0.993	0.000
Q12.2 Coloboma of lens	0.007	0.993	0.000
Q12.1 Congenital displaced lens	0.007	0.993	0.000
K51.5 Mucosal proctocolitis	0.007	0.993	0.000
K86.1 Other chronic pancreatitis	0.007	0.993	0.000
Q76.0 Spina bifida occulta	0.007	0.993	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.007	0.993	0.000
Q10.0 Congenital ptosis	0.007	0.993	0.000
K52.1 Toxic gastro-enteritis and colitis	0.007	0.993	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.007	0.993	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.006	0.993	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.006	0.993	0.000
Q74.3 Arthrogryposis multiplex congenita	0.006	0.993	0.000
Q79.0 Congenital diaphragmatic hernia	0.007	0.993	0.000
Q31 Congenital malformations of larynx	0.006	0.993	0.000
Q24.4 Congenital subaortic stenosis	0.006	0.993	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.993	0.007
Q52 Other congenital malformations of female genitalia	0.006	0.993	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.007	0.993	0.000
Q23.3 Congenital mitral insufficiency	0.006	0.993	0.000
Q69.9 Polydactyly, unspecified	0.006	0.994	0.000
Q69.2 Accessory toe(s)	0.006	0.994	0.000
Q69.1 Accessory thumb(s)	0.006	0.994	0.000
Q69.0 Accessory finger(s)	0.006	0.994	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.006	0.994	0.000
Q71.8 Other reduction defects of upper limb(s)	0.006	0.994	0.000
Q71.6 Lobster-claw hand	0.006	0.994	0.000
Q71.5 Longitudinal reduction defect of ulna	0.006	0.994	0.000
Q71.4 Longitudinal reduction defect of radius	0.006	0.994	0.000
Q71.3 Congenital absence of hand and finger(s)	0.006	0.994	0.000
Q71.2 Congenital absence of both forearm and hand	0.006	0.994	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.006	0.994	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.006	0.994	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.006	0.994	0.000
Q72.8 Other reduction defects of lower limb(s)	0.006	0.994	0.000
Q72.7 Split foot	0.006	0.994	0.000
Q72.6 Longitudinal reduction defect of fibula	0.006	0.994	0.000
Q72.5 Longitudinal reduction defect of tibia	0.006	0.994	0.000
Q72.4 Longitudinal reduction defect of femur	0.006	0.994	0.000
Q72.3 Congenital absence of foot and toe(s)	0.006	0.994	0.000
Q72.2 Congenital absence of both lower leg and foot	0.006	0.994	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.006	0.994	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.006	0.994	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.006	0.994	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.006	0.994	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.006	0.994	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.006	0.994	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.006	0.994	0.000
Q75.5 Oculomandibular dysostosis	0.006	0.994	0.000
Q75.4 Mandibulofacial dysostosis	0.006	0.994	0.000
Q75.3 Macrocephaly	0.006	0.994	0.000
Q75.2 Hypertelorism	0.006	0.994	0.000
Q75.1 Craniofacial dysostosis	0.006	0.994	0.000
Q75.0 Craniosynostosis	0.006	0.994	0.000
Q34 Other congenital malformations of respiratory system	0.006	0.994	0.000
Q33 Congenital malformations of lung	0.006	0.994	0.000
Q32 Congenital malformations of trachea and bronchus	0.006	0.994	0.000
Q30 Congenital malformations of nose	0.006	0.994	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.994	0.006
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.006	0.994	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.006	0.994	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.006	0.994	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.006	0.994	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.006	0.994	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.006	0.994	0.000
Q78.8 Other specified osteochondrodysplasias	0.006	0.994	0.000
Q78.6 Multiple congenital exostoses	0.006	0.994	0.000
Q78.5 Metaphyseal dysplasia	0.006	0.994	0.000
Q78.4 Enchondromatosis	0.006	0.994	0.000
Q78.3 Progressive diaphyseal dysplasia	0.006	0.994	0.000
Q78.2 Osteopetrosis	0.006	0.994	0.000
Q78.1 Polyostotic fibrous dysplasia	0.006	0.994	0.000
Q87.4 Marfan's syndrome	0.006	0.994	0.000
Q51 Congenital malformations of uterus and cervix	0.006	0.994	0.000
Q70.9 Syndactyly, unspecified	0.006	0.994	0.000
Q70.4 Polysyndactyly	0.006	0.994	0.000
Q70.2 Fused toes	0.006	0.994	0.000
Q70.1 Webbed fingers	0.006	0.994	0.000
Q70.0 Fused fingers	0.006	0.994	0.000
Q35 Cleft palate	0.006	0.994	0.000
Q37 Cleft palate with cleft lip	0.006	0.994	0.000
Q36 Cleft lip	0.006	0.994	0.000
K50-K52 Noninfective enteritis and colitis	0.006	0.994	0.000
Q22.1 Congenital pulmonary valve stenosis	0.006	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.006	0.994	0.000
Q10.7 Congenital malformation of orbit	0.006	0.994	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.006	0.994	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.006	0.994	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.006	0.994	0.000
Q10.3 Other congenital malformations of eyelid	0.006	0.994	0.000
Q10.2 Congenital entropion	0.006	0.994	0.000
Q10.1 Congenital ectropion	0.006	0.994	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.006	0.994	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.006	0.994	0.000
Q27.1 Congenital renal artery stenosis	0.006	0.994	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.006	0.994	0.000
Q70.3 Webbed toes	0.006	0.994	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.006	0.994	0.000
Q96.9 Turner's syndrome, unspecified	0.006	0.994	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.006	0.994	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.006	0.994	0.000
Q64.4 Malformation of urachus	0.006	0.994	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.006	0.994	0.000
Q50.5 Embryonic cyst of broad ligament	0.006	0.994	0.000
Q90 Down's syndrome	0.006	0.994	0.000
Q17.5 Prominent ear	0.006	0.994	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.006	0.994	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.006	0.994	0.000
Q79.5 Other congenital malformations of abdominal wall	0.006	0.994	0.000
Q79.4 Prune belly syndrome	0.006	0.994	0.000
Q79.3 Gastroschisis	0.006	0.994	0.000
Q79.2 Exomphalos	0.006	0.994	0.000
Q17.9 Congenital malformation of ear, unspecified	0.006	0.994	0.000
Q17.8 Other specified congenital malformations of ear	0.006	0.994	0.000
Q17.4 Misplaced ear	0.006	0.994	0.000
Q17.3 Other misshapen ear	0.006	0.994	0.000
Q17.2 Microtia	0.006	0.994	0.000
Q17.1 Macrotia	0.006	0.994	0.000
Q17.0 Accessory auricle	0.006	0.994	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.006	0.994	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.006	0.994	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.006	0.994	0.000
Q13.5 Blue sclera	0.006	0.994	0.000
Q13.4 Other congenital corneal malformations	0.006	0.994	0.000
Q13.3 Congenital corneal opacity	0.006	0.994	0.000
Q13.2 Other congenital malformations of iris	0.006	0.994	0.000
Q13.1 Absence of iris	0.006	0.994	0.000
Q13.0 Coloboma of iris	0.006	0.994	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.006	0.994	0.000
Q16.5 Congenital malformation of inner ear	0.006	0.994	0.000
Q16.4 Other congenital malformations of middle ear	0.006	0.994	0.000
Q16.3 Congenital malformation of ear ossicles	0.006	0.994	0.000
Q16.2 Absence of eustachian tube	0.006	0.994	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.006	0.994	0.000
Q16.0 Congenital absence of (ear) auricle	0.006	0.994	0.000
Q24.5 Malformation of coronary vessels	0.006	0.994	0.000
S65 Injury of blood vessels at wrist and hand level	0.006	0.994	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.006	0.994	0.000
Q24.3 Pulmonary infundibular stenosis	0.006	0.994	0.000
Q24.2 Cor triatriatum	0.006	0.994	0.000
Q24.1 Levocardia	0.006	0.994	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.994	0.006
Q55 Other congenital malformations of male genital organs	0.006	0.994	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.006	0.994	0.000
Q79.1 Other congenital malformations of diaphragm	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.006	0.994	0.000
Q50.3 Other congenital malformations of ovary	0.006	0.994	0.000
Q50.2 Congenital torsion of ovary	0.006	0.994	0.000
Q50.1 Developmental ovarian cyst	0.006	0.994	0.000
Q50.0 Congenital absence of ovary	0.006	0.994	0.000
Q11.3 Macrophthalmos	0.006	0.994	0.000
Q11.2 Microphthalmos	0.006	0.994	0.000
Q11.0 Cystic eyeball	0.006	0.994	0.000
K52.3 Indeterminate colitis	0.006	0.994	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.006	0.994	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.006	0.994	0.000
Q14.3 Congenital malformation of choroid	0.006	0.994	0.000
Q14.2 Congenital malformation of optic disk	0.006	0.994	0.000
Q14.0 Congenital malformation of vitreous humour	0.006	0.994	0.000
Q24.6 Congenital heart block	0.006	0.994	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.006	0.994	0.000
Q64.8 Other specified congenital malformations of urinary system	0.006	0.994	0.000
Q64.6 Congenital diverticulum of bladder	0.006	0.994	0.000
Q64.5 Congenital absence of bladder and urethra	0.006	0.994	0.000
Q64.2 Congenital posterior urethral valves	0.006	0.994	0.000
Q64.1 Exstrophy of urinary bladder	0.006	0.994	0.000
Q64.0 Epispadias	0.006	0.994	0.000
R47.0 Dysphasia and aphasia	0.006	0.994	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.005	0.994	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.994	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.005	0.994	0.000
Q77.6 Chondroectodermal dysplasia	0.005	0.994	0.000
Q77.5 Diastrophic dysplasia	0.005	0.994	0.000
Q77.3 Chondrodysplasia punctata	0.005	0.994	0.000
Q77.2 Short rib syndrome	0.005	0.994	0.000
Q77.1 Thanatophoric short stature	0.005	0.994	0.000
Q77.0 Achondrogenesis	0.005	0.994	0.000
Q11.1 Other anophthalmos	0.005	0.994	0.000
Q27.4 Congenital phlebectasia	0.006	0.994	0.000
Q27.2 Other congenital malformations of renal artery	0.006	0.994	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.006	0.994	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.005	0.994	0.000
Q52.1 Doubling of vagina	0.006	0.994	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.006	0.994	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.006	0.994	0.000
Q14.1 Congenital malformation of retina	0.005	0.994	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.006	0.994	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.005	0.994	0.000
S65.5 Injury of blood vessel(s) of other finger	0.006	0.994	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.994	0.006
K86 Other diseases of pancreas	0.006	0.994	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.994	0.000
C44.5 Skin of trunk	0.000	0.995	0.005
S69 Other and unspecified injuries of wrist and hand	0.005	0.995	0.000
Q96.8 Other variants of Turner's syndrome	0.005	0.995	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.005	0.995	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.005	0.995	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.005	0.995	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.005	0.995	0.000
Q96.0 Karyotype 45,X	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
Q79.6 Ehlers-Danlos syndrome	0.005	0.995	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.005	0.995	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.005	0.995	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.005	0.995	0.000
Q31.0 Web of larynx	0.005	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000
Q84 Other congenital malformations of integument	0.005	0.995	0.000
Q81 Epidermolysis bullosa	0.005	0.995	0.000
Q80 Congenital ichthyosis	0.005	0.995	0.000
K86.9 Disease of pancreas, unspecified	0.005	0.995	0.000
Q62.8 Other congenital malformations of ureter	0.005	0.995	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.005	0.995	0.000
Q62.6 Malposition of ureter	0.005	0.995	0.000
Q62.4 Agenesis of ureter	0.005	0.995	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.005	0.995	0.000
Q62.2 Congenital megaloureter	0.005	0.995	0.000
Q62.0 Congenital hydronephrosis	0.005	0.995	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.005	0.995	0.000
S67 Crushing injury of wrist and hand	0.005	0.995	0.000
S64.3 Injury of digital nerve of thumb	0.005	0.995	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.005	0.995	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.005	0.995	0.000
Q31.8 Other congenital malformations of larynx	0.005	0.995	0.000
Q31.5 Congenital laryngomalacia	0.005	0.995	0.000
Q31.4 Congenital laryngeal stridor	0.005	0.995	0.000
Q31.2 Laryngeal hypoplasia	0.005	0.995	0.000
Q31.1 Congenital subglottic stenosis	0.005	0.995	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
Q53 Undescended testicle	0.005	0.995	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.005	0.995	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.005	0.995	0.000
Q52.7 Other congenital malformations of vulva	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations