TreeWAS – Variant ID: rs8109288

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.163	0.837
J40-J47 Chronic lower respiratory diseases	0.161	0.839
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.160	0.840
J44 Other chronic obstructive pulmonary disease	0.154	0.846
Chapter X Diseases of the respiratory system	0.154	0.846
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.151	0.849
J45 Asthma	0.150	0.850
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.148	0.852
T85 Complications of other internal prosthetic devices, implants and grafts	0.146	0.854
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.145	0.855
J45.9 Asthma, unspecified	0.144	0.856
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.144	0.856
T84.0 Mechanical complication of internal joint prosthesis	0.142	0.858
J40 Bronchitis, not specified as acute or chronic	0.141	0.859
J30-J39 Other diseases of upper respiratory tract	0.140	0.860
S50-S59 Injuries to the elbow and forearm	0.134	0.866
J80-J84 Other respiratory diseases principally affecting the interstitium	0.134	0.866
J09-J18 Influenza and pneumonia	0.133	0.867
J46 Status asthmaticus	0.131	0.869
S90-S99 Injuries to the ankle and foot	0.129	0.871
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.128	0.871
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.128	0.872
T80 Complications following infusion, transfusion and therapeutic injection	0.128	0.872
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.128	0.872
T84.2 Mechanical complication of internal fixation device of other bones	0.127	0.873
J44.8 Other specified chronic obstructive pulmonary disease	0.127	0.873
J34 Other disorders of nose and nasal sinuses	0.126	0.874
J00-J06 Acute upper respiratory infections	0.125	0.875
T83.0 Mechanical complication of urinary (indwelling) catheter	0.124	0.876
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.123	0.877
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.123	0.877
T86 Failure and rejection of transplanted organs and tissues	0.120	0.880
J33 Nasal polyp	0.120	0.880
S70-S79 Injuries to the hip and thigh	0.120	0.880
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.120	0.880
S60-S69 Injuries to the wrist and hand	0.120	0.880
S52 Fracture of forearm	0.119	0.880
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.119	0.881
J43 Emphysema	0.119	0.881
T88 Other complications of surgical and medical care, not elsewhere classified	0.119	0.881
J30 Vasomotor and allergic rhinitis	0.119	0.881
T87 Complications peculiar to reattachment and amputation	0.117	0.883
J15 Bacterial pneumonia, not elsewhere classified	0.117	0.883
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.117	0.883
T15-T19 Effects of foreign body entering through natural orifice	0.116	0.884
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.116	0.884
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.116	0.884
J41 Simple and mucopurulent chronic bronchitis	0.115	0.884
T36-T50 Poisoning by drugs, medicaments and biological substances	0.115	0.885
J42 Unspecified chronic bronchitis	0.115	0.885
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.115	0.885
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.115	0.885
T84.3 Mechanical complication of other bone devices, implants and grafts	0.115	0.885
Chapter VII Diseases of the eye and adnexa	0.115	0.885
J02 Acute pharyngitis	0.115	0.885
T79-T79 Certain early complications of trauma	0.114	0.885
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.114	0.886
# Top node	0.112	0.888
J84 Other interstitial pulmonary diseases	0.112	0.888
J60-J70 Lung diseases due to external agents	0.112	0.888
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.112	0.888
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.111	0.889
S52.5 Fracture of lower end of radius	0.110	0.889
T83.1 Mechanical complication of other urinary devices and implants	0.110	0.890
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.110	0.890
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.110	0.890
T33-T35 Frostbite	0.109	0.891
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.109	0.891
T26-T28 Burns and corrosions confined to eye and internal organs	0.109	0.891
T20-T25 Burns and corrosions of external body surface, specified by site	0.109	0.891
T00-T07 Injuries involving multiple body regions	0.109	0.891
S10-S19 Injuries to the neck	0.109	0.891
J45.8 Mixed asthma	0.108	0.892
J45.1 Nonallergic asthma	0.108	0.892
J02.9 Acute pharyngitis, unspecified	0.108	0.892
H25-H28 Disorders of lens	0.107	0.893
S91 Open wound of ankle and foot	0.107	0.893
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.107	0.893
S20-S29 Injuries to the thorax	0.107	0.893
T84.1 Mechanical complication of internal fixation device of bones of limb	0.107	0.893
J34.8 Other specified disorders of nose and nasal sinuses	0.107	0.893
H25 Senile cataract	0.106	0.894
S32 Fracture of lumbar spine and pelvis	0.106	0.894
S62 Fracture at wrist and hand level	0.105	0.895
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.105	0.895
T85.2 Mechanical complication of intraocular lens	0.105	0.895
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.105	0.895
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.105	0.895
T85.4 Mechanical complication of breast prosthesis and implant	0.104	0.896
S52.50 Fracture of lower end of radius (closed)	0.104	0.896
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.104	0.896
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.104	0.896
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.104	0.896
T83.3 Mechanical complication of intra-uterine contraceptive device	0.104	0.896
T83.2 Mechanical complication of graft of urinary organ	0.104	0.896
H30-H36 Disorders of choroid and retina	0.104	0.896
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.103	0.896
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.103	0.896
H25.1 Senile nuclear cataract	0.104	0.896
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.103	0.897
J81 Pulmonary oedema	0.103	0.897
T80.2 Infections following infusion, transfusion and therapeutic injection	0.103	0.897
S30 Superficial injury of abdomen, lower back and pelvis	0.103	0.897
J80 Adult respiratory distress syndrome	0.102	0.897
J33.0 Polyp of nasal cavity	0.102	0.898
T81 Complications of procedures, not elsewhere classified	0.102	0.898
J30.1 Allergic rhinitis due to pollen	0.101	0.898
J18 Pneumonia, organism unspecified	0.101	0.899
J34.2 Deviated nasal septum	0.101	0.899
J47 Bronchiectasis	0.101	0.899
S50 Superficial injury of forearm	0.101	0.899
J37 Chronic laryngitis and laryngotracheitis	0.100	0.899
J34.3 Hypertrophy of nasal turbinates	0.100	0.900
J95-J99 Other diseases of the respiratory system	0.100	0.900
J15.0 Pneumonia due to Klebsiella pneumoniae	0.100	0.900
T66-T78 Other and unspecified effects of external causes	0.100	0.900
S99 Other and unspecified injuries of ankle and foot	0.099	0.900
J45.0 Predominantly allergic asthma	0.099	0.901
S72 Fracture of femur	0.099	0.901
J32 Chronic sinusitis	0.098	0.902
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.098	0.902
S92 Fracture of foot, except ankle	0.098	0.902
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.097	0.903
Chapter XX External causes of morbidity and mortality	0.096	0.904
S59 Other and unspecified injuries of forearm	0.096	0.904
S58 Traumatic amputation of forearm	0.096	0.904
S57 Crushing injury of forearm	0.096	0.904
S56 Injury of muscle and tendon at forearm level	0.096	0.904
S55 Injury of blood vessels at forearm level	0.096	0.904
S54 Injury of nerves at forearm level	0.096	0.904
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.096	0.904
S51 Open wound of forearm	0.096	0.904
J82 Pulmonary eosinophilia, not elsewhere classified	0.096	0.904
S80-S89 Injuries to the knee and lower leg	0.096	0.904
J84.9 Interstitial pulmonary disease, unspecified	0.095	0.904
J33.9 Nasal polyp, unspecified	0.095	0.904
J17 Pneumonia in diseases classified elsewhere	0.095	0.905
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.095	0.905
J12 Viral pneumonia, not elsewhere classified	0.095	0.905
J11 Influenza, virus not identified	0.095	0.905
J10 Influenza due to identified influenza virus	0.095	0.905
J14 Pneumonia due to Haemophilus influenzae	0.095	0.905
J09 Influenza due to certain identified influenza virus	0.095	0.905
H35 Other retinal disorders	0.095	0.905
H04 Disorders of lachrymal system	0.095	0.905
J15.1 Pneumonia due to Pseudomonas	0.094	0.906
T82.1 Mechanical complication of cardiac electronic device	0.094	0.906
J20-J22 Other acute lower respiratory infections	0.093	0.907
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.093	0.907
S98 Traumatic amputation of ankle and foot	0.093	0.907
S97 Crushing injury of ankle and foot	0.093	0.907
S96 Injury of muscle and tendon at ankle and foot level	0.093	0.907
S95 Injury of blood vessels at ankle and foot level	0.093	0.907
S94 Injury of nerves at ankle and foot level	0.093	0.907
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.093	0.907
S90 Superficial injury of ankle and foot	0.093	0.907
H46-H48 Disorders of optic nerve and visual pathways	0.093	0.907
S68 Traumatic amputation of wrist and hand	0.093	0.907
S40-S49 Injuries to the shoulder and upper arm	0.092	0.907
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.092	0.908
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.092	0.908
T82.4 Mechanical complication of vascular dialysis catheter	0.092	0.908
T82.3 Mechanical complication of other vascular grafts	0.092	0.908
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.092	0.908
T82.0 Mechanical complication of heart valve prosthesis	0.092	0.908
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.092	0.908
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.092	0.908
T80.6 Other serum reactions	0.092	0.908
T80.5 Anaphylactic shock due to serum	0.092	0.908
T80.4 Rh incompatibility reaction	0.092	0.908
T80.3 ABO incompatibility reaction	0.092	0.908
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.092	0.908
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.092	0.908
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.092	0.908
S37 Injury of urinary and pelvic organs	0.092	0.908
S36 Injury of intra-abdominal organs	0.092	0.908
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.092	0.908
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.092	0.908
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.092	0.908
S31 Open wound of abdomen, lower back and pelvis	0.092	0.908
S91.3 Open wound of other parts of foot	0.091	0.909
J34.1 Cyst and mucocele of nose and nasal sinus	0.091	0.909
J34.0 Abscess, furuncle and carbuncle of nose	0.091	0.909
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.090	0.909
S52.1 Fracture of upper end of radius	0.090	0.910
S66 Injury of muscle and tendon at wrist and hand level	0.090	0.910
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.090	0.910
H35.8 Other specified retinal disorders	0.090	0.910
J13 Pneumonia due to Streptococcus pneumoniae	0.090	0.910
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.090	0.910
J04 Acute laryngitis and tracheitis	0.090	0.910
J01 Acute sinusitis	0.090	0.910
T86.8 Failure and rejection of other transplanted organs and tissues	0.090	0.910
J36 Peritonsillar abscess	0.089	0.911
J39 Other diseases of upper respiratory tract	0.089	0.911
J90-J94 Other diseases of pleura	0.089	0.911
J03 Acute tonsillitis	0.089	0.911
J43.9 Emphysema, unspecified	0.089	0.911
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.089	0.911
J30.3 Other allergic rhinitis	0.089	0.911
H34 Retinal vascular occlusions	0.088	0.912
T79 Certain early complications of trauma, not elsewhere classified	0.088	0.912
J38.0 Paralysis of vocal cords and larynx	0.088	0.912
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.088	0.912
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.087	0.912
T18 Foreign body in alimentary tract	0.087	0.912
T17 Foreign body in respiratory tract	0.087	0.912
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.087	0.913
S67 Crushing injury of wrist and hand	0.087	0.913
S62.5 Fracture of thumb	0.087	0.913
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.086	0.913
T86.4 Liver transplant failure and rejection	0.086	0.913
T86.3 Heart-lung transplant failure and rejection	0.086	0.913
T86.2 Heart transplant failure and rejection	0.086	0.913
T86.1 Kidney transplant failure and rejection	0.086	0.913
T86.0 Bone-marrow transplant rejection	0.086	0.913
J33.1 Polypoid sinus degeneration	0.086	0.913
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.087	0.913
S78 Traumatic amputation of hip and thigh	0.086	0.914
S77 Crushing injury of hip and thigh	0.086	0.914
S76 Injury of muscle and tendon at hip and thigh level	0.086	0.914
S75 Injury of blood vessels at hip and thigh level	0.086	0.914
S74 Injury of nerves at hip and thigh level	0.086	0.914
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.086	0.914
S71 Open wound of hip and thigh	0.086	0.914
S70 Superficial injury of hip and thigh	0.086	0.914
J38.1 Polyp of vocal cord and larynx	0.086	0.914
J30.4 Allergic rhinitis, unspecified	0.086	0.914
H25.8 Other senile cataract	0.086	0.914
S69 Other and unspecified injuries of wrist and hand	0.086	0.914
S65 Injury of blood vessels at wrist and hand level	0.086	0.914
S60 Superficial injury of wrist and hand	0.086	0.914
H04.5 Stenosis and insufficiency of lachrymal passages	0.086	0.914
S52.9 Fracture of forearm, part unspecified	0.086	0.914
S52.8 Fracture of other parts of forearm	0.086	0.914
S52.7 Multiple fractures of forearm	0.086	0.914
S52.4 Fracture of shafts of both ulna and radius	0.086	0.914
S52.3 Fracture of shaft of radius	0.086	0.914
S52.2 Fracture of shaft of ulna	0.086	0.914
J43.8 Other emphysema	0.085	0.914
J43.2 Centrilobular emphysema	0.085	0.914
J43.1 Panlobular emphysema	0.085	0.914
J43.0 MacLeod's syndrome	0.085	0.914
S62.3 Fracture of other metacarpal bone	0.086	0.914
T88.9 Complication of surgical and medical care, unspecified	0.085	0.914
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.085	0.914
T88.5 Other complications of anaesthesia	0.085	0.914
T88.3 Malignant hyperthermia due to anaesthesis	0.085	0.914
T88.2 Shock due to anaesthesia	0.085	0.914
T88.1 Other complications following immunisation, not elsewhere classified	0.085	0.914
T88.0 Infection following immunisation	0.085	0.914
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.085	0.914
J30.2 Other seasonal allergic rhinitis	0.085	0.915
J30.0 Vasomotor rhinitis	0.085	0.915
H10-H13 Disorders of conjunctiva	0.085	0.915
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.085	0.915
J33.8 Other polyp of sinus	0.085	0.915
S64 Injury of nerves at wrist and hand level	0.085	0.915
S79 Other and unspecified injuries of hip and thigh	0.085	0.915
Chapter IV Endocrine, nutritional and metabolic diseases	0.085	0.915
H25.9 Senile cataract, unspecified	0.084	0.916
T87.6 Other and unspecified complications of amputation stump	0.084	0.916
T87.5 Necrosis of amputation stump	0.084	0.916
T87.4 Infection of amputation stump	0.084	0.916
T87.3 Neuroma of amputation stump	0.084	0.916
T87.2 Complications of other reattached body part	0.084	0.916
T87.1 Complications of reattached (part of) lower extremity	0.084	0.916
T87.0 Complications of reattached (part of) upper extremity	0.084	0.916
T88.7 Unspecified adverse effect of drug or medicament	0.084	0.916
S32.5 Fracture of pubis	0.084	0.916
J15.9 Bacterial pneumonia, unspecified	0.084	0.916
J15.8 Other bacterial pneumonia	0.084	0.916
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.084	0.916
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.084	0.916
J15.5 Pneumonia due to Escherichia coli	0.084	0.916
J15.4 Pneumonia due to other streptococci	0.084	0.916
J15.3 Pneumonia due to streptococcus, group B	0.084	0.916
J15.2 Pneumonia due to staphylococcus	0.084	0.916
S52.6 Fracture of lower end of both ulna and radius	0.084	0.916
J38.7 Other diseases of larynx	0.084	0.916
T88.4 Failed or difficult intubation	0.083	0.916
T19 Foreign body in genito-urinary tract	0.083	0.916
T15 Foreign body on external eye	0.083	0.916
T16 Foreign body in ear	0.083	0.916
J18.9 Pneumonia, unspecified	0.084	0.916
J00 Acute nasopharyngitis [common cold]	0.083	0.917
T90 Sequelae of injuries of head	0.083	0.917
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.083	0.917
J41.1 Mucopurulent chronic bronchitis	0.083	0.917
J41.0 Simple chronic bronchitis	0.083	0.917
J44.9 Chronic obstructive pulmonary disease, unspecified	0.083	0.917
Chapter XXII Codes for special purposes	0.083	0.917
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.083	0.917
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.083	0.917
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.083	0.917
T46 Poisoning by agents primarily affecting the cardiovascular system	0.083	0.917
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.083	0.917
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.083	0.917
T41 Poisoning by anaesthetics and therapeutic gases	0.083	0.917
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.083	0.917
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.083	0.917
T36 Poisoning by systemic antibiotics	0.083	0.917
J02.8 Acute pharyngitis due to other specified organisms	0.082	0.917
J02.0 Streptococcal pharyngitis	0.082	0.917
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.083	0.917
T81.3 Disruption of operation wound, not elsewhere classified	0.082	0.918
J84.1 Other interstitial pulmonary diseases with fibrosis	0.082	0.918
S32.4 Fracture of acetabulum	0.082	0.918
T51 Toxic effect of alcohol	0.082	0.918
J69 Pneumonitis due to solids and liquids	0.082	0.918
T81.7 Vascular complications following a procedure, not elsewhere classified	0.082	0.918
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.082	0.918
H40-H42 Glaucoma	0.081	0.919
S92.5 Fracture of other toe	0.081	0.919
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.081	0.919
Chapter XVI Certain conditions originating in the perinatal period	0.081	0.919
S62.6 Fracture of other finger	0.081	0.919
J84.8 Other specified interstitial pulmonary diseases	0.080	0.919
J84.0 Alveolar and parietoalveolar conditions	0.080	0.919
J70 Respiratory conditions due to other external agents	0.080	0.919
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.080	0.919
J67 Hypersensitivity pneumonitis due to organic dust	0.080	0.919
J66 Airway disease due to specific organic dust	0.080	0.919
J63 Pneumoconiosis due to other inorganic dusts	0.080	0.919
J62 Pneumoconiosis due to dust containing silica	0.080	0.919
J65 Pneumoconiosis associated with tuberculosis	0.080	0.919
J64 Unspecified pneumoconiosis	0.080	0.919
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.080	0.919
J60 Coalworker's pneumoconiosis	0.080	0.919
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.080	0.920
T42.4 Benzodiazepines	0.080	0.920
T14 Injury of unspecified body region	0.080	0.920
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.080	0.920
T65 Toxic effect of other and unspecified substances	0.080	0.920
T63 Toxic effect of contact with venomous animals	0.080	0.920
T62 Toxic effect of other noxious substances eaten as food	0.080	0.920
T61 Toxic effect of noxious substances eaten as seafood	0.080	0.920
T60 Toxic effect of pesticides	0.080	0.920
T59 Toxic effect of other gases, fumes and vapours	0.080	0.920
T57 Toxic effect of other inorganic substances	0.080	0.920
T56 Toxic effect of metals	0.080	0.920
T54 Toxic effect of corrosive substances	0.080	0.920
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.080	0.920
T52 Toxic effect of organic solvents	0.080	0.920
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.080	0.920
T58 Toxic effect of carbon monoxide	0.080	0.920
T55 Toxic effect of soaps and detergents	0.080	0.920
H53-H54 Visual disturbances and blindness	0.080	0.920
Chapter XII Diseases of the skin and subcutaneous tissue	0.080	0.920
S52.51 Fracture of lower end of radius (open)	0.079	0.920
S80 Superficial injury of lower leg	0.079	0.921
Chapter XV Pregnancy, childbirth and the puerperium	0.079	0.921
S52.0 Fracture of upper end of ulna	0.079	0.921
T13 Other injuries of lower limb, level unspecified	0.079	0.921
T11 Other injuries of upper limb, level unspecified	0.079	0.921
T09 Other injuries of spine and trunk, level unspecified	0.079	0.921
T12.X1 Fracture of lower limb, level unspecified (open)	0.079	0.921
T12.X0 Fracture of lower limb, level unspecified (closed)	0.079	0.921
T12 Fracture of lower limb, level unspecified	0.079	0.921
T10.X1 Fracture of upper limb, level unspecified (open)	0.079	0.921
T10.X0 Fracture of upper limb, level unspecified (closed)	0.079	0.921
T10 Fracture of upper limb, level unspecified	0.079	0.921
T08.X1 Fracture of spine, level unspecified (open)	0.079	0.921
T08.X0 Fracture of spine, level unspecified (closed)	0.079	0.921
T08 Fracture of spine, level unspecified	0.079	0.921
J38.6 Stenosis of larynx	0.079	0.921
J38.5 Laryngeal spasm	0.079	0.921
J38.2 Nodules of vocal cords	0.079	0.921
S19 Other and unspecified injuries of neck	0.078	0.922
S17 Crushing injury of neck	0.078	0.922
S15 Injury of blood vessels at neck level	0.078	0.922
S14 Injury of nerves and spinal cord at neck level	0.078	0.922
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.078	0.922
S12 Fracture of neck	0.078	0.922
S11 Open wound of neck	0.078	0.922
S10 Superficial injury of neck	0.078	0.922
S18 Traumatic amputation at neck level	0.078	0.922
S16 Injury of muscle and tendon at neck level	0.078	0.922
T06 Other injuries involving multiple body regions, not elsewhere classified	0.078	0.922
T05 Traumatic amputations involving multiple body regions	0.078	0.922
T04 Crushing injuries involving multiple body regions	0.078	0.922
T03 Dislocations, sprains and strains involving multiple body regions	0.078	0.922
T02 Fractures involving multiple body regions	0.078	0.922
T01 Open wounds involving multiple body regions	0.078	0.922
T00 Superficial injuries involving multiple body regions	0.078	0.922
T07 Unspecified multiple injuries	0.078	0.922
T25 Burn and corrosion of ankle and foot	0.078	0.922
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.078	0.922
T23 Burn and corrosion of wrist and hand	0.078	0.922
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.078	0.922
T21 Burn and corrosion of trunk	0.078	0.922
T20 Burn and corrosion of head and neck	0.078	0.922
T28 Burn and corrosion of other internal organs	0.078	0.922
T27 Burn and corrosion of respiratory tract	0.078	0.922
T26 Burn and corrosion confined to eye and adnexa	0.078	0.922
T32 Corrosions classified according to extent of body surface involved	0.078	0.922
T31 Burns classified according to extent of body surface involved	0.078	0.922
T30 Burn and corrosion, body region unspecified	0.078	0.922
T29 Burns and corrosions of multiple body regions	0.078	0.922
T35 Frostbite involving multiple body regions and unspecified frostbite	0.078	0.922
T34 Frostbite with tissue necrosis	0.078	0.922
T33 Superficial frostbite	0.078	0.922
S99.9 Unspecified injury of ankle and foot	0.078	0.922
S22 Fracture of rib(s), sternum and thoracic spine	0.078	0.922
S32.0 Fracture of lumbar vertebra	0.078	0.922
J32.2 Chronic ethmoidal sinusitis	0.077	0.922
H34.8 Other retinal vascular occlusions	0.077	0.923
H46 Optic neuritis	0.077	0.923
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.077	0.923
H27 Other disorders of lens	0.077	0.923
S91.7 Multiple open wounds of ankle and foot	0.077	0.923
S91.2 Open wound of toe(s) with damage to nail	0.077	0.923
S91.1 Open wound of toe(s) without damage to nail	0.077	0.923
S91.0 Open wound of ankle	0.077	0.923
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.077	0.923
J32.0 Chronic maxillary sinusitis	0.077	0.923
J38.4 Oedema of larynx	0.077	0.923
S50.9 Superficial injury of forearm, unspecified	0.077	0.923
S29 Other and unspecified injuries of thorax	0.077	0.923
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.077	0.923
S26 Injury of heart	0.077	0.923
S25 Injury of blood vessels of thorax	0.077	0.923
S24 Injury of nerves and spinal cord at thorax level	0.077	0.923
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.077	0.923
S21 Open wound of thorax	0.077	0.923
S20 Superficial injury of thorax	0.077	0.923
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.077	0.923
S72.1 Pertrochanteric fracture	0.077	0.923
H55-H59 Other disorders of eye and adnexa	0.076	0.924
H00 Hordeolum and chalazion	0.076	0.924
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.076	0.924
H25.2 Senile cataract, morgagnian type	0.076	0.924
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.076	0.924
S32.7 Multiple fractures of lumbar spine and pelvis	0.076	0.924
S32.3 Fracture of ilium	0.076	0.924
S32.2 Fracture of coccyx	0.076	0.924
S32.1 Fracture of sacrum	0.076	0.924
S62.8 Fracture of other and unspecified parts of wrist and hand	0.076	0.924
S62.7 Multiple fractures of fingers	0.076	0.924
S62.4 Multiple fractures of metacarpal bones	0.076	0.924
S62.2 Fracture of first metacarpal bone	0.076	0.924
S62.1 Fracture of other carpal bone(s)	0.076	0.924
S62.0 Fracture of navicular [scaphoid] bone of hand	0.076	0.924
H04.1 Other disorders of lachrymal gland	0.075	0.925
H32 Chorioretinal disorders in diseases classified elsewhere	0.075	0.925
H31 Other disorders of choroid	0.075	0.925
H30 Chorioretinal inflammation	0.075	0.925
H35.0 Background retinopathy and retinal vascular changes	0.075	0.925
Chapter VIII Diseases of the ear and mastoid process	0.075	0.925
J85 Abscess of lung and mediastinum	0.074	0.925
T98 Sequelae of other and unspecified effects of external causes	0.074	0.925
T95 Sequelae of burns, corrosions and frostbite	0.074	0.925
T94 Sequelae of injuries involving multiple and unspecified body regions	0.074	0.925
T91 Sequelae of injuries of neck and trunk	0.074	0.925
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.074	0.925
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.074	0.925
S72.4 Fracture of lower end of femur	0.074	0.925
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.074	0.926
S72.3 Fracture of shaft of femur	0.074	0.926
Y84.2 Radiological procedure and radiotherapy	0.074	0.926
H01 Other inflammation of eyelid	0.074	0.926
S72.0 Fracture of neck of femur	0.074	0.926
H05 Disorders of orbit	0.074	0.926
H03 Disorders of eyelid in diseases classified elsewhere	0.074	0.926
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.074	0.926
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.074	0.926
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.074	0.926
S30.2 Contusion of external genital organs	0.074	0.926
S30.1 Contusion of abdominal wall	0.074	0.926
S30.0 Contusion of lower back and pelvis	0.074	0.926
T81.8 Other complications of procedures, not elsewhere classified	0.074	0.926
J32.8 Other chronic sinusitis	0.074	0.926
S27 Injury of other and unspecified intrathoracic organs	0.074	0.926
S62.50 Fracture of thumb (closed)	0.074	0.926
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.073	0.926
H43-H45 Disorders of vitreous body and globe	0.073	0.926
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.073	0.927
T81.9 Unspecified complication of procedure	0.073	0.927
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.073	0.927
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.073	0.927
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.073	0.927
J18.8 Other pneumonia, organism unspecified	0.073	0.927
J18.2 Hypostatic pneumonia, unspecified	0.073	0.927
T92 Sequelae of injuries of upper limb	0.073	0.927
S50.8 Other superficial injuries of forearm	0.072	0.928
S50.7 Multiple superficial injuries of forearm	0.072	0.928
S50.1 Contusion of other and unspecified parts of forearm	0.072	0.928
S50.0 Contusion of elbow	0.072	0.928
J37.1 Chronic laryngotracheitis	0.072	0.928
J37.0 Chronic laryngitis	0.072	0.928
H52 Disorders of refraction and accommodation	0.072	0.928
X60-X84 Intentional self-harm	0.072	0.928
J99 Respiratory disorders in diseases classified elsewhere	0.072	0.928
J96 Respiratory failure, not elsewhere classified	0.072	0.928
T75 Effects of other external causes	0.072	0.928
T74 Maltreatment syndromes	0.072	0.928
T73 Effects of other deprivation	0.072	0.928
T70 Effects of air pressure and water pressure	0.072	0.928
T69 Other effects of reduced temperature	0.072	0.928
T67 Effects of heat and light	0.072	0.928

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations