TreeWAS – Variant ID: rs8181385

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K75.8 Other specified inflammatory liver diseases	0.304	0.696	0.000
K75 Other inflammatory liver diseases	0.281	0.719	0.000
K75.4 Autoimmune hepatitis	0.273	0.727	0.000
K75.9 Inflammatory liver disease, unspecified	0.260	0.740	0.000
K75.2 Nonspecific reactive hepatitis	0.202	0.798	0.000
K75.1 Phlebitis of portal vein	0.202	0.798	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.196	0.804	0.000
K75.0 Abscess of liver	0.125	0.875	0.000
K70-K77 Diseases of liver	0.030	0.970	0.000
K73 Chronic hepatitis, not elsewhere classified	0.026	0.974	0.000
K74.0 Hepatic fibrosis	0.026	0.974	0.000
K74 Fibrosis and cirrhosis of liver	0.025	0.975	0.000
K71 Toxic liver disease	0.024	0.976	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.023	0.977	0.000
K77 Liver disorders in diseases classified elsewhere	0.022	0.978	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.020	0.980	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.980	0.020
K74.5 Biliary cirrhosis, unspecified	0.020	0.980	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.020	0.980	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.019	0.981	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.019	0.981	0.000
K73.9 Chronic hepatitis, unspecified	0.019	0.981	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.019	0.981	0.000
K74.4 Secondary biliary cirrhosis	0.018	0.981	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.018	0.981	0.000
K74.1 Hepatic sclerosis	0.018	0.981	0.000
G82.1 Spastic paraplegia	0.000	0.982	0.018
K71.9 Toxic liver disease, unspecified	0.018	0.982	0.000
K71.8 Toxic liver disease with other disorders of liver	0.018	0.982	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.018	0.982	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.018	0.982	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.018	0.982	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.018	0.982	0.000
K71.2 Toxic liver disease with acute hepatitis	0.018	0.982	0.000
K71.0 Toxic liver disease with cholestasis	0.017	0.983	0.000
G82 Paraplegia and tetraplegia	0.000	0.983	0.017
K77.8 Liver disorders in other diseases classified elsewhere	0.016	0.984	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
T93.2 Sequelae of other fractures of lower limb	0.015	0.985	0.000
G82.5 Tetraplegia, unspecified	0.000	0.985	0.015
G83 Other paralytic syndromes	0.000	0.987	0.013
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.987	0.013
K74.3 Primary biliary cirrhosis	0.013	0.987	0.000
G82.4 Spastic tetraplegia	0.000	0.987	0.013
G83.2 Monoplegia of upper limb	0.000	0.987	0.013
G82.3 Flaccid tetraplegia	0.000	0.988	0.012
G82.0 Flaccid paraplegia	0.000	0.988	0.012
G80 Infantile cerebral palsy	0.000	0.988	0.012
S82.4 Fracture of fibula alone	0.000	0.988	0.012
G83.9 Paralytic syndrome, unspecified	0.000	0.989	0.011
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.989	0.011
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.989	0.011
G80.9 Infantile cerebral palsy, unspecified	0.000	0.989	0.011
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.989	0.011
S83.2 Tear of meniscus, current	0.000	0.989	0.011
K72 Hepatic failure, not elsewhere classified	0.011	0.989	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.989	0.011
G82.2 Paraplegia, unspecified	0.000	0.990	0.010
G83.4 Cauda equina syndrome	0.000	0.990	0.010
G83.1 Monoplegia of lower limb	0.000	0.990	0.010
G83.5 Locked-in syndrome	0.000	0.990	0.010
G83.3 Monoplegia, unspecified	0.000	0.990	0.010
G83.0 Diplegia of upper limbs	0.000	0.990	0.010
G83.8 Other specified paralytic syndromes	0.000	0.990	0.009
I78.1 Naevus, nonneoplastic	0.000	0.990	0.010
G80.2 Infantile hemiplegia	0.000	0.991	0.009
G80.8 Other infantile cerebral palsy	0.000	0.991	0.009
G80.4 Ataxic cerebral palsy	0.000	0.991	0.009
G80.3 Dyskinetic cerebral palsy	0.000	0.991	0.009
S82.41 Fracture of fibula alone (open)	0.000	0.991	0.008
E04.1 Non-toxic single thyroid nodule	0.000	0.992	0.008
G80.1 Spastic diplegia	0.000	0.992	0.008
S83.7 Injury to multiple structures of knee	0.000	0.992	0.008
S83.1 Dislocation of knee	0.000	0.992	0.008
G80.0 Spastic cerebral palsy	0.000	0.992	0.008
S83.3 Tear of articular cartilage of knee, current	0.000	0.992	0.007
E21.0 Primary hyperparathyroidism	0.000	0.993	0.007
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.993	0.007
K72.1 Chronic hepatic failure	0.007	0.993	0.000
K74.6 Other and unspecified cirrhosis of liver	0.007	0.993	0.000
S83.0 Dislocation of patella	0.000	0.993	0.007
G81 Hemiplegia	0.000	0.993	0.007
R87.6 Abnormal cytological findings	0.006	0.994	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.994	0.006
H65.3 Chronic mucoid otitis media	0.006	0.994	0.000
I78 Diseases of capillaries	0.000	0.994	0.006
H65.0 Acute serous otitis media	0.006	0.994	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.006	0.994	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.994	0.006
H65 Nonsuppurative otitis media	0.006	0.994	0.000
I99 Other and unspecified disorders of circulatory system	0.006	0.994	0.000
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
S82 Fracture of lower leg, including ankle	0.000	0.994	0.006
G81.0 Flaccid hemiplegia	0.000	0.995	0.005
M67.1 Other contracture of tendon (sheath)	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.000	0.995	0.005
G81.1 Spastic hemiplegia	0.000	0.995	0.005
K72.9 Hepatic failure, unspecified	0.005	0.995	0.000
C44.0 Skin of lip	0.005	0.995	0.000
D32.0 Cerebral meninges	0.005	0.995	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.005	0.995	0.000
S82.1 Fracture of upper end of tibia	0.000	0.995	0.005
S82.0 Fracture of patella	0.000	0.995	0.005
I78.9 Disease of capillaries, unspecified	0.000	0.995	0.005
K72.0 Acute and subacute hepatic failure	0.004	0.995	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.005	0.995	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
F52.2 Failure of genital response	0.000	0.995	0.004
T93.1 Sequelae of fracture of femur	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.996	0.004
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.000	0.996	0.004
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
S82.3 Fracture of lower end of tibia	0.000	0.996	0.004
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.996	0.004
M67 Other disorders of synovium and tendon	0.004	0.996	0.000
H65.1 Other acute nonsuppurative otitis media	0.004	0.996	0.000
S82.7 Multiple fractures of lower leg	0.000	0.996	0.004
S82.5 Fracture of medial malleolus	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.000	0.996	0.004
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.004	0.996	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.996	0.004
S82.01 Fracture of patella (open)	0.000	0.996	0.003
S82.31 Fracture of lower end of tibia (open)	0.000	0.996	0.004
I61 Intracerebral haemorrhage	0.004	0.996	0.000
M54.56 Low back pain (Lumbar region)	0.004	0.996	0.000
M67.0 Short Achilles tendon (acquired)	0.003	0.997	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.997	0.003
S82.2 Fracture of shaft of tibia	0.000	0.997	0.003
S88 Traumatic amputation of lower leg	0.000	0.997	0.003
S87 Crushing injury of lower leg	0.000	0.997	0.003
S85 Injury of blood vessels at lower leg level	0.000	0.997	0.003
S84 Injury of nerves at lower leg level	0.000	0.997	0.003
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.997	0.003
I61.6 Intracerebral haemorrhage, multiple localised	0.003	0.997	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.997	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.003	0.997	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.003	0.997	0.000
M67.3 Transient synovitis	0.003	0.997	0.000
I61.8 Other intracerebral haemorrhage	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.997	0.003
D47.4 Osteomyelofibrosis	0.003	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
S82.81 Fractures of other parts of lower leg (open)	0.000	0.997	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.997	0.003
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
M67.4 Ganglion	0.003	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
O21.0 Mild hyperemesis gravidarum	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.003	0.997	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.003	0.997	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.997	0.003
S82.70 Multiple fractures of lower leg (closed)	0.000	0.997	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.997	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.997	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.997	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.997	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.997	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.997	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.997	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.997	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.997	0.002
S85.5 Injury of popliteal vein	0.000	0.997	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.997	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.997	0.002
S85.2 Injury of peroneal artery	0.000	0.997	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.997	0.002
S85.0 Injury of popliteal artery	0.000	0.997	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.997	0.002
S87.0 Crushing injury of knee	0.000	0.997	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.997	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.997	0.002
S88.0 Traumatic amputation at knee level	0.000	0.997	0.002
D32 Benign neoplasm of meninges	0.003	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.997	0.000
R87 Abnormal findings in specimens from female genital organs	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
S82.86 Maisonneuve's fracture	0.000	0.997	0.002
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.002
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.997	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.997	0.000
S86.0 Injury of Achilles tendon	0.000	0.997	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.997	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.997	0.002
D32.1 Spinal meninges	0.002	0.997	0.000
E06.4 Drug-induced thyroiditis	0.002	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.997	0.000
E06.1 Subacute thyroiditis	0.002	0.997	0.000
E06.0 Acute thyroiditis	0.002	0.997	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
K70 Alcoholic liver disease	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
J33.8 Other polyp of sinus	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
S81 Open wound of lower leg	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
R87.0 Abnormal level of enzymes	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.000	0.998	0.002
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
M16 Coxarthrosis [arthrosis of hip]	0.000	0.998	0.002
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.002	0.998	0.000
F50.9 Eating disorder, unspecified	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
R87.8 Other abnormal findings	0.002	0.998	0.000
R87.5 Abnormal microbiological findings	0.002	0.998	0.000
R87.4 Abnormal immunological findings	0.002	0.998	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R87.1 Abnormal level of hormones	0.002	0.998	0.000
F50 Eating disorders	0.000	0.998	0.002
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.002
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.000	0.998	0.002
D32.9 Meninges, unspecified	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
D35.1 Parathyroid gland	0.000	0.998	0.002
S89 Other and unspecified injuries of lower leg	0.000	0.998	0.002
S82.21 Fracture of shaft of tibia (open)	0.000	0.998	0.002
D35.2 Pituitary gland	0.000	0.998	0.002
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
D13.1 Stomach	0.002	0.998	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.998	0.002
T75.4 Effects of electric current	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.000	0.998	0.002
R87.9 Unspecified abnormal finding	0.002	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
R87.7 Abnormal histological findings	0.002	0.998	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
F50.8 Other eating disorders	0.000	0.998	0.002
F50.5 Vomiting associated with other psychological disturbances	0.000	0.998	0.002
F50.4 Overeating associated with other psychological disturbances	0.000	0.998	0.002
F50.3 Atypical bulimia nervosa	0.000	0.998	0.002
F50.1 Atypical anorexia nervosa	0.000	0.998	0.002
G45.3 Amaurosis fugax	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
S81.0 Open wound of knee	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
R14 Flatulence and related conditions	0.002	0.998	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.998	0.002
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
S89.7 Multiple injuries of lower leg	0.000	0.998	0.001
S89.1 Other specified injuries of lower leg	0.000	0.998	0.001
S89.0 Multiple injuries of lower leg	0.000	0.998	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.001	0.998	0.000
O62.2 Other uterine inertia	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
K92.0 Haematemesis	0.002	0.998	0.000
M16.7 Other secondary coxarthrosis	0.000	0.998	0.002
K86.2 Cyst of pancreas	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.001
F55 Abuse of non-dependence-producing substances	0.000	0.998	0.001
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.000	0.998	0.001
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
I84.0 Internal thrombosed haemorrhoids	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
D41.4 Bladder	0.002	0.998	0.000
O26.2 Pregnancy care of habitual aborter	0.000	0.998	0.002
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.001
G45.0 Vertebro-basilar artery syndrome	0.001	0.998	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.001
M25.74 Osteophyte (Hand)	0.001	0.999	0.000
M16.3 Other dysplastic coxarthrosis	0.000	0.999	0.001
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.999	0.001
F51 Nonorganic sleep disorders	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
G00.1 Pneumococcal meningitis	0.001	0.999	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.999	0.001
C69.3 Choroid	0.000	0.999	0.001
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999	0.000
K70.1 Alcoholic hepatitis	0.001	0.999	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.999	0.001
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
H20.9 Iridocyclitis, unspecified	0.000	0.999	0.001
D04.2 Skin of ear and external auricular canal	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
S89.8 Other specified injuries of lower leg	0.000	0.999	0.001
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.999	0.001
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.999	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.999	0.001
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.999	0.001
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.999	0.001
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.999	0.001
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
K70.4 Alcoholic hepatic failure	0.001	0.999	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
F53.9 Puerperal mental disorder, unspecified	0.000	0.999	0.001
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.999	0.001
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.999	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.999	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.999	0.001
Z31.2 In vitro fertilisation	0.001	0.999	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999	0.000
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.999	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.000	0.999	0.001
F51.8 Other nonorganic sleep disorders	0.000	0.999	0.001
F51.5 Nightmares	0.000	0.999	0.001
F51.3 Sleepwalking [somnambulism]	0.000	0.999	0.001
F51.2 Nonorganic disorder of the sleep-wake schedule	0.000	0.999	0.001
F51.1 Nonorganic hypersomnia	0.000	0.999	0.001
F51.0 Nonorganic insomnia	0.000	0.999	0.001
I95-I99 Other and unspecified disorders of the circulatory system	0.001	0.999	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.001	0.999	0.000
H20.1 Chronic iridocyclitis	0.000	0.999	0.001
H81.2 Vestibular neuronitis	0.000	0.999	0.001
I49.3 Ventricular premature depolarisation	0.000	0.999	0.001
I97.1 Other functional disturbances following cardiac surgery	0.001	0.999	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.999	0.001
X51.9 Unspecified place	0.001	0.999	0.000
L21 Seborrhoeic dermatitis	0.001	0.999	0.000
D18.0 Haemangioma, any site	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.001	0.999	0.000
M16.5 Other posttraumatic coxarthrosis	0.000	0.999	0.001
G45 Transient cerebral ischaemic attacks and related syndromes	0.001	0.999	0.000
D41.1 Renal pelvis	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.001	0.999	0.000
T75.1 Drowning and nonfatal submersion	0.001	0.999	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.999	0.001
Z01.4 Gynaecological examination (general)(routine)	0.001	0.999	0.000
C21.1 Anal canal	0.000	0.999	0.001
D35.9 Endocrine gland, unspecified	0.000	0.999	0.001
D35.8 Pluriglandular involvement	0.000	0.999	0.001
D35.7 Other specified endocrine glands	0.000	0.999	0.001
D35.6 Aortic body and other paraganglia	0.000	0.999	0.001
D35.5 Carotid body	0.000	0.999	0.001
D35.4 Pineal gland	0.000	0.999	0.001
D35.3 Craniopharyngeal duct	0.000	0.999	0.001
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.999	0.001
K70.9 Alcoholic liver disease, unspecified	0.001	0.999	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.001	0.999	0.000
T40.1 Heroin	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
F51.4 Sleep terrors [night terrors]	0.000	0.999	0.001
G90.3 Multisystem degeneration	0.000	0.999	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.999	0.000
I97.0 Postcardiotomy syndrome	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
T51.0 Ethanol	0.001	0.999	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.999	0.001
M77.57 Other enthesopathy of foot-Ankle/Foot	0.001	0.999	0.000
L21.8 Other seborrhoeic dermatitis	0.001	0.999	0.000
L21.1 Seborrhoeic infantile dermatitis	0.001	0.999	0.000
L21.0 Seborrhoea capitis	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
D41.0 Kidney	0.001	0.999	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.001	0.999	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.001	0.999	0.000
L91.8 Other hypertrophic disorders of skin	0.001	0.999	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
S80 Superficial injury of lower leg	0.000	0.999	0.001
D12.2 Ascending colon	0.001	0.999	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.001	0.999	0.000
H05.0 Acute inflammation of orbit	0.000	0.999	0.001
S80.7 Multiple superficial injuries of lower leg	0.000	0.999	0.001
X78.0 Home	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
D41.9 Urinary organ, unspecified	0.001	0.999	0.000
D41.7 Other urinary organs	0.001	0.999	0.000
D41.3 Urethra	0.001	0.999	0.000
D48.0 Bone and articular cartilage	0.001	0.999	0.000
W19.3 Sports and athletics area	0.000	0.999	0.001
H20 Iridocyclitis	0.000	0.999	0.001
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.999	0.001
C44.4 Skin of scalp and neck	0.001	0.999	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
D41.2 Ureter	0.001	0.999	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.999	0.001
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
G00 Bacterial meningitis, not elsewhere classified	0.001	0.999	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.999	0.001
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations