TreeWAS – Variant ID: rs854572

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R06.8 Other and unspecified abnormalities of breathing	0.070	0.930	0.000
Z50.0 Cardiac rehabilitation	0.000	0.980	0.020
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.990	0.010
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.992	0.008
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.992	0.008
R82 Other abnormal findings in urine	0.000	0.993	0.007
I77.1 Stricture of artery	0.000	0.994	0.006
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.994	0.006
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.994	0.006
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.006	0.994	0.000
S61.8 Open wound of other parts of wrist and hand	0.006	0.994	0.000
R82.4 Acetonuria	0.000	0.994	0.005
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.005
R82.1 Myoglobinuria	0.000	0.995	0.005
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.995	0.005
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
R82.3 Haemoglobinuria	0.000	0.995	0.005
R82.2 Biliuria	0.000	0.995	0.005
R82.0 Chyluria	0.000	0.995	0.005
M67.43 Ganglion, wrist	0.005	0.995	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.005	0.995	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
M06.0 Seronegative rheumatoid arthritis	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
D73.0 Hyposplenism	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
O80.9 Single spontaneous delivery, unspecified	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.004	0.996	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.996	0.004
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.996	0.004
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
F22.0 Delusional disorder	0.000	0.996	0.004
H60.8 Other otitis externa	0.000	0.996	0.004
H60.3 Other infective otitis externa	0.000	0.996	0.004
M06.08 Seronegative rheumatoid arthritis (Other)	0.004	0.996	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
M67.4 Ganglion	0.004	0.996	0.000
H60 Otitis externa	0.000	0.996	0.004
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.996	0.000
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
N43.3 Hydrocele, unspecified	0.000	0.996	0.004
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.000	0.997	0.003
K80.8 Other cholelithiasis	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.000	0.997	0.003
J98.8 Other specified respiratory disorders	0.003	0.997	0.000
H27.0 Aphakia	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.000	0.997	0.003
H60.0 Abscess of external ear	0.000	0.997	0.003
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.997	0.003
M67.49 Ganglion, multiple sites	0.003	0.997	0.000
M67.45 Ganglion, hip	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M67.1 Other contracture of tendon (sheath)	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.000	0.997	0.003
H60.5 Acute otitis externa, non-infective	0.000	0.997	0.003
I38 Endocarditis, valve unspecified	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.000	0.997	0.003
L05.0 Pilonidal cyst with abscess	0.000	0.997	0.003
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.997	0.003
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.003	0.997	0.000
M67 Other disorders of synovium and tendon	0.003	0.997	0.000
W44.0 Home	0.003	0.997	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.003	0.997	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
R07.1 Chest pain on breathing	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.997	0.003
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.000	0.998	0.002
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.998	0.002
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
F22 Persistent delusional disorders	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
L84 Corns and callosities	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
X60.8 Other specified place	0.002	0.998	0.000
L05 Pilonidal cyst	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.002
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
K85 Acute pancreatitis	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.000	0.998	0.002
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.002
G45.4 Transient global amnesia	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
G45.3 Amaurosis fugax	0.000	0.998	0.002
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
G45.0 Vertebro-basilar artery syndrome	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.000	0.998	0.002
H54 Blindness and low vision	0.000	0.998	0.002
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.998	0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.001	0.998	0.000
M67.0 Short Achilles tendon (acquired)	0.001	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
H05.2 Exophthalmic conditions	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.000	0.998	0.002
Y40.4 Tetracyclines	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.998	0.002
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.001
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
W44.8 Other specified place	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
T02.50 Fractures involving multiple regions of both lower limbs (closed)	0.001	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.001
I86.4 Gastric varices	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.001	0.998	0.000
R89.7 Abnormal histological findings	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.998	0.001
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
H54.5 Low vision, one eye	0.000	0.998	0.001
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.001
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
W44 Foreign body entering into or through eye or natural orifice	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
I84.5 External haemorrhoids without complication	0.002	0.998	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.998	0.001
M66.0 Rupture of popliteal cyst	0.001	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
G91.1 Obstructive hydrocephalus	0.000	0.998	0.001
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.000	0.998	0.001
Y48.3 Local anaesthetics	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
C44.0 Skin of lip	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
M60.99 Myositis, unspecified (Site unspecified)	0.001	0.999	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.001	0.999	0.000
F30.0 Hypomania	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
Y55.4 Expectorants	0.001	0.999	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.001	0.999	0.000
N43 Hydrocele and spermatocele	0.000	0.999	0.001
C49.2 Connective and soft tissue of lower limb, including hip	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
W44.9 Unspecified place	0.001	0.999	0.000
L90.0 Lichen sclerosus et atrophicus	0.001	0.999	0.000
Y47.1 Benzodiazepines	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
S02.51 Fracture of tooth (open)	0.000	0.999	0.001
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.999	0.001
W44.5 Trade and service area	0.001	0.999	0.000
W44.7 Farm	0.001	0.999	0.000
W44.6 Industrial and construction area	0.001	0.999	0.000
W44.4 Street and highway	0.001	0.999	0.000
W44.3 Sports and athletics area	0.001	0.999	0.000
W44.2 School, other institution and public administrative area	0.001	0.999	0.000
W44.1 Residential institution	0.001	0.999	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
D10.0 Lip	0.000	0.999	0.001
D14.0 Middle ear, nasal cavity and accessory sinuses	0.001	0.999	0.000
R89.5 Abnormal microbiological findings	0.001	0.999	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.999	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.999	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.999	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.999	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.999	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.999	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.999	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.999	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.999	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.001	0.999	0.000
M54.4 Lumbago with sciatica	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.001	0.999	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.001	0.999	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
H54.4 Blindness, one eye	0.000	0.999	0.001
Z76.9 Persons encountering health services in unspecified circumstances	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.999	0.001
N43.1 Infected hydrocele	0.000	0.999	0.001
O14.1 Severe preeclampsia	0.000	0.999	0.001
M65-M68 Disorders of synovium and tendon	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.999	0.001
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.999	0.001
M65.04 Abscess of tendon sheath (Hand)	0.001	0.999	0.000
W44.99 Foreign body entering into or through eye or natural orifice, Unspecified place , During unspecified activity	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.999	0.001
I86.1 Scrotal varices	0.001	0.999	0.000
R25.3 Fasciculation	0.001	0.999	0.000
Y40.6 Rifamycins	0.001	0.999	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.999	0.001
N43.0 Encysted hydrocele	0.000	0.999	0.001
O00.1 Tubal pregnancy	0.000	0.999	0.001
T02.5 Fractures involving multiple regions of both lower limbs	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
X60.5 Trade and service area	0.001	0.999	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.001	0.999	0.000
M34.1 CR(E)ST syndrome	0.000	0.999	0.001
M65.8 Other synovitis and tenosynovitis	0.001	0.999	0.000
N43.2 Other hydrocele	0.000	0.999	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
W44.59 Foreign body entering into or through eye or natural orifice; Trade and service area;During unspecified activity	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
C62.9 Testis, unspecified	0.000	0.999	0.001
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.999	0.001
I67 Other cerebrovascular diseases	0.000	0.999	0.001
M66 Spontaneous rupture of synovium and tendon	0.001	0.999	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.999	0.001
M54.44 Lumbago with sciatica-Thoracic	0.000	0.999	0.001
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.999	0.001
M54.42 Lumbago with sciatica-Cervical	0.000	0.999	0.001
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.999	0.001
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.999	0.001
G31.1 Senile degeneration of brain, not elsewhere classified	0.001	0.999	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.999	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.999	0.001
I86.3 Vulval varices	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
N71.9 Inflammatory disease of uterus, unspecified	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.999	0.001
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
M65.4 Radial styloid tenosynovitis [de Quervain]	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y60.5 During heart catheterisation	0.000	0.999	0.001
K50 Crohn's disease [regional enteritis]	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
C15.5 Lower third of oesophagus	0.001	0.999	0.000
D73.8 Other diseases of spleen	0.001	0.999	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.001	0.999	0.000
T02.51 Fractures involving multiple regions of both lower limbs (open)	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.999	0.001
K91.1 Postgastric surgery syndromes	0.001	0.999	0.000
M65.0 Abscess of tendon sheath	0.001	0.999	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.001	0.999	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.001	0.999	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.001	0.999	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.999	0.001
I87.1 Compression of vein	0.001	0.999	0.000
M66.1 Rupture of synovium	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
X60.9 Unspecified place	0.001	0.999	0.000
X60.0 Home	0.001	0.999	0.000
X60.7 Farm	0.001	0.999	0.000
X60.6 Industrial and construction area	0.001	0.999	0.000
X60.4 Street and highway	0.001	0.999	0.000
X60.3 Sports and athletics area	0.001	0.999	0.000
X60.1 Residential institution	0.001	0.999	0.000
Y00.9 Unspecified place	0.000	0.999	0.001
Y40.3 Macrolides	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
D73 Diseases of spleen	0.001	0.999	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.999	0.001
I67.5 Moyamoya disease	0.000	0.999	0.001
I67.4 Hypertensive encephalopathy	0.000	0.999	0.001
I67.3 Progressive vascular leukoencephalopathy	0.000	0.999	0.001
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.001	0.999	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
X60.2 School, other institution and public administrative area	0.001	0.999	0.000
Y40.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
G82 Paraplegia and tetraplegia	0.001	0.999	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.999	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.999	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.999	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.999	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.999	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.999	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.999	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.999	0.001
G31.2 Degeneration of nervous system due to alcohol	0.001	0.999	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.001	0.999	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.001	0.999	0.000
M65.08 Abscess of tendon sheath (Other)	0.001	0.999	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.001	0.999	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.001	0.999	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.001	0.999	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.001	0.999	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.001	0.999	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.001	0.999	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.001	0.999	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.999	0.001
K50.8 Other Crohn's disease	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations