TreeWAS – Variant ID: rs874499

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C44.5 Skin of trunk	1.000	0.000	0.000
C44.4 Skin of scalp and neck	0.983	0.017	0.000
C44.6 Skin of upper limb, including shoulder	0.964	0.036	0.000
C44.0 Skin of lip	0.944	0.056	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
C44.2 Skin of ear and external auricular canal	0.600	0.400	0.000
C44.7 Skin of lower limb, including hip	0.578	0.422	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.471	0.528	0.000
C44.1 Skin of eyelid, including canthus	0.266	0.734	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.179	0.821	0.000
E66.8 Other obesity	0.000	0.923	0.077
E66 Obesity	0.000	0.948	0.052
F20.0 Paranoid schizophrenia	0.051	0.949	0.000
F20 Schizophrenia	0.048	0.952	0.000
F20.9 Schizophrenia, unspecified	0.046	0.954	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.954	0.046
F20.5 Residual schizophrenia	0.039	0.961	0.000
E66.1 Drug-induced obesity	0.000	0.962	0.037
E65-E68 Obesity and other hyperalimentation	0.000	0.963	0.037
E65 Localised adiposity	0.000	0.965	0.035
F20.8 Other schizophrenia	0.035	0.965	0.000
F20.6 Simple schizophrenia	0.035	0.965	0.000
F20.4 Postschizophrenic depression	0.035	0.965	0.000
F20.3 Undifferentiated schizophrenia	0.035	0.965	0.000
F20.2 Catatonic schizophrenia	0.035	0.965	0.000
F20.1 Hebephrenic schizophrenia	0.035	0.965	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.031	0.969	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.030	0.970	0.000
E66.9 Obesity, unspecified	0.000	0.972	0.028
E66.0 Obesity due to excess calories	0.000	0.972	0.028
F22 Persistent delusional disorders	0.027	0.973	0.000
E67 Other hyperalimentation	0.000	0.973	0.027
E68 Sequelae of hyperalimentation	0.000	0.973	0.027
F22.0 Delusional disorder	0.025	0.975	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.975	0.025
F23 Acute and transient psychotic disorders	0.024	0.976	0.000
F25 Schizoaffective disorders	0.023	0.977	0.000
F28 Other nonorganic psychotic disorders	0.023	0.977	0.000
F24 Induced delusional disorder	0.023	0.977	0.000
F21 Schizotypal disorder	0.023	0.977	0.000
F29 Unspecified nonorganic psychosis	0.022	0.978	0.000
F22.9 Persistent delusional disorder, unspecified	0.020	0.980	0.000
F22.8 Other persistent delusional disorders	0.020	0.980	0.000
E67.8 Other specified hyperalimentation	0.000	0.980	0.019
E67.3 Hypervitaminosis D	0.000	0.980	0.019
E67.2 Megavitamin-B6 syndrome	0.000	0.980	0.019
E67.1 Hypercarotenaemia	0.000	0.980	0.019
E67.0 Hypervitaminosis A	0.000	0.980	0.019
F23.3 Other acute predominantly delusional psychotic disorders	0.019	0.981	0.000
F25.2 Schizoaffective disorder, mixed type	0.019	0.981	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.019	0.981	0.000
F23.8 Other acute and transient psychotic disorders	0.018	0.982	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.018	0.982	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.018	0.982	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.017	0.983	0.000
F25.8 Other schizoaffective disorders	0.017	0.983	0.000
F25.9 Schizoaffective disorder, unspecified	0.017	0.983	0.000
F25.0 Schizoaffective disorder, manic type	0.016	0.984	0.000
F25.1 Schizoaffective disorder, depressive type	0.015	0.984	0.000
C43 Malignant melanoma of skin	0.013	0.987	0.000
J38.3 Other diseases of vocal cords	0.000	0.989	0.011
C43.2 Malignant melanoma of ear and external auricular canal	0.010	0.989	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.010	0.990	0.000
C43.8 Overlapping malignant melanoma of skin	0.009	0.990	0.000
C43.0 Malignant melanoma of lip	0.009	0.990	0.000
S43.0 Dislocation of shoulder joint	0.000	0.991	0.009
C43.1 Malignant melanoma of eyelid, including canthus	0.008	0.992	0.000
C43.4 Malignant melanoma of scalp and neck	0.008	0.992	0.000
J38.7 Other diseases of larynx	0.000	0.992	0.008
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.992	0.008
J38.4 Oedema of larynx	0.000	0.993	0.007
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.007	0.993	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.007	0.993	0.000
M45 Ankylosing spondylitis	0.007	0.993	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.993	0.007
C43.7 Malignant melanoma of lower limb, including hip	0.006	0.994	0.000
J38.6 Stenosis of larynx	0.000	0.994	0.006
C43.9 Malignant melanoma of skin, unspecified	0.006	0.994	0.000
O20.0 Threatened abortion	0.006	0.994	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.006	0.994	0.000
H92.1 Otorrhoea	0.005	0.995	0.000
J38.5 Laryngeal spasm	0.000	0.995	0.005
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.005	0.995	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.005	0.995	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.005	0.995	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.005	0.995	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.005	0.995	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.995	0.005
S80.9 Superficial injury of lower leg, unspecified	0.005	0.995	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.005	0.995	0.000
O81.4 Vacuum extractor delivery	0.005	0.995	0.000
J38.2 Nodules of vocal cords	0.000	0.995	0.005
O42 Premature rupture of membranes	0.000	0.995	0.005
J38.0 Paralysis of vocal cords and larynx	0.000	0.995	0.005
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.995	0.005
I73.0 Raynaud's syndrome	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.996	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
H92.2 Otorrhagia	0.004	0.996	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.996	0.004
H92.0 Otalgia	0.004	0.996	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.004	0.996	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.996	0.003
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.996	0.003
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.996	0.003
S43.2 Dislocation of sternoclavicular joint	0.000	0.996	0.003
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.997	0.003
M07.30 Other psoriatic arthropathies (Multiple sites)	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.997	0.003
M13.0 Polyarthritis, unspecified	0.003	0.997	0.000
R13 Dysphagia	0.003	0.997	0.000
C43.5 Malignant melanoma of trunk	0.003	0.997	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.003	0.997	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.003	0.997	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.997	0.003
S43.4 Sprain and strain of shoulder joint	0.000	0.997	0.003
V18.0 Driver injured in nontraffic accident	0.003	0.997	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
F01 Vascular dementia	0.003	0.997	0.000
F00 Dementia in Alzheimer's disease	0.003	0.997	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.003	0.997	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.997	0.003
F00.1 Dementia in Alzheimer's disease with late onset	0.003	0.997	0.000
Chapter V Mental and behavioural disorders	0.003	0.997	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
N32.3 Diverticulum of bladder	0.003	0.997	0.000
R86.8 Other abnormal findings	0.003	0.997	0.000
F05.9 Delirium, unspecified	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
M13.08 Polyarthritis, unspecified (Other)	0.003	0.997	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.003	0.997	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.003	0.997	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.003	0.997	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.003	0.997	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.997	0.000
F01.1 Multi-infarct dementia	0.002	0.997	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.997	0.003
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.003	0.997	0.000
R86.0 Abnormal level of enzymes	0.002	0.997	0.000
F09 Unspecified organic or symptomatic mental disorder	0.002	0.997	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.997	0.000
M25.78 Osteophyte (Other)	0.000	0.998	0.002
C50.1 Central portion of breast	0.000	0.998	0.002
F06.2 Organic delusional [schizophrenia-like] disorder	0.002	0.998	0.000
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
R86 Abnormal findings in specimens from male genital organs	0.002	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.002	0.998	0.000
F51 Nonorganic sleep disorders	0.002	0.998	0.000
F70-F79 Mental retardation	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
F50 Eating disorders	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.002	0.998	0.000
F06.5 Organic dissociative disorder	0.002	0.998	0.000
F06.4 Organic anxiety disorder	0.002	0.998	0.000
F06.3 Organic mood [affective] disorders	0.002	0.998	0.000
F06.1 Organic catatonic disorder	0.002	0.998	0.000
F06.0 Organic hallucinosis	0.002	0.998	0.000
D26.9 Uterus, unspecified	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
F55 Abuse of non-dependence-producing substances	0.002	0.998	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
F51.0 Nonorganic insomnia	0.002	0.998	0.000
I31 Other diseases of pericardium	0.000	0.998	0.002
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
M49.5 Collapsed vertebra in diseases classified elsewhere	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.998	0.002
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.002	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.1 Postencephalitic syndrome	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
R86.9 Unspecified abnormal finding	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.000	0.998	0.002
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.002	0.998	0.000
F11 Mental and behavioural disorders due to use of opioids	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
F13.2 Dependence syndrome	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.002
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998	0.000
F95 Tic disorders	0.002	0.998	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.002	0.998	0.000
F93 Emotional disorders with onset specific to childhood	0.002	0.998	0.000
F92 Mixed disorders of conduct and emotions	0.002	0.998	0.000
F91 Conduct disorders	0.002	0.998	0.000
F90 Hyperkinetic disorders	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
R86.7 Abnormal histological findings	0.002	0.998	0.000
R86.6 Abnormal cytological findings	0.002	0.998	0.000
R86.5 Abnormal microbiological findings	0.002	0.998	0.000
R86.4 Abnormal immunological findings	0.002	0.998	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R86.1 Abnormal level of hormones	0.002	0.998	0.000
W19.9 Unspecified place	0.000	0.998	0.002
F99-F99 Unspecified mental disorder	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.002	0.998	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.002	0.998	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.002	0.998	0.000
F51.8 Other nonorganic sleep disorders	0.002	0.998	0.000
F51.5 Nightmares	0.002	0.998	0.000
F51.4 Sleep terrors [night terrors]	0.002	0.998	0.000
F51.3 Sleepwalking [somnambulism]	0.002	0.998	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.002	0.998	0.000
F51.1 Nonorganic hypersomnia	0.002	0.998	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
F78 Other mental retardation	0.002	0.998	0.000
F73 Profound mental retardation	0.002	0.998	0.000
F72 Severe mental retardation	0.002	0.998	0.000
F71 Moderate mental retardation	0.002	0.998	0.000
F70 Mild mental retardation	0.002	0.998	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
F07.0 Organic personality disorder	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
F11.0 Acute intoxication	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.002	0.998	0.000
M49 Spondylopathies in diseases classified elsewhere	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
F50.8 Other eating disorders	0.002	0.998	0.000
F50.5 Vomiting associated with other psychological disturbances	0.002	0.998	0.000
F50.4 Overeating associated with other psychological disturbances	0.002	0.998	0.000
F50.3 Atypical bulimia nervosa	0.002	0.998	0.000
F50.1 Atypical anorexia nervosa	0.002	0.998	0.000
F53.9 Puerperal mental disorder, unspecified	0.002	0.998	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
M07.6 Other enteropathic arthropathies	0.002	0.998	0.000
F79 Unspecified mental retardation	0.002	0.998	0.000
F50.9 Eating disorder, unspecified	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
W13.9 Unspecified place	0.000	0.998	0.002
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.002	0.998	0.000
F80-F89 Disorders of psychological development	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M07.69 Other enteropathic arthropathies (Site unspecified)	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
I31.8 Other specified diseases of pericardium	0.000	0.998	0.002
I31.2 Haemopericardium, not elsewhere classified	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.000	0.998	0.002
S41.1 Open wound of upper arm	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.002	0.998	0.000
M45-M49 Spondylopathies	0.002	0.998	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.002	0.998	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.002	0.998	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.002	0.998	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.002	0.998	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.002	0.998	0.000
F11.2 Dependence syndrome	0.002	0.998	0.000
F19.2 Dependence syndrome	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
F11.1 Harmful use	0.002	0.998	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.002	0.998	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.002	0.998	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.002	0.998	0.000
M13 Other arthritis	0.002	0.998	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
R50.0 Fever with chills	0.000	0.998	0.002
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
F11.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F11.8 Other mental and behavioural disorders	0.002	0.998	0.000
F11.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F11.6 Amnesic syndrome	0.002	0.998	0.000
F11.5 Psychotic disorder	0.002	0.998	0.000
F11.4 Withdrawal state with delirium	0.002	0.998	0.000
F11.3 Withdrawal state	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
M07.5 Arthropathy in ulcerative colitis	0.002	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.998	0.000
M07.2 Psoriatic spondylitis	0.002	0.998	0.000
M07.1 Arthritis mutilans	0.002	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.998	0.000
F13.9 Unspecified mental and behavioural disorder	0.001	0.998	0.000
F13.8 Other mental and behavioural disorders	0.001	0.998	0.000
F13.7 Residual and late-onset psychotic disorder	0.001	0.998	0.000
F13.6 Amnesic syndrome	0.001	0.998	0.000
F13.5 Psychotic disorder	0.001	0.998	0.000
F13.4 Withdrawal state with delirium	0.001	0.998	0.000
F13.3 Withdrawal state	0.001	0.998	0.000
F13.1 Harmful use	0.001	0.998	0.000
F13.0 Acute intoxication	0.001	0.998	0.000
F90.9 Hyperkinetic disorder, unspecified	0.001	0.998	0.000
F90.8 Other hyperkinetic disorders	0.001	0.998	0.000
F90.1 Hyperkinetic conduct disorder	0.001	0.998	0.000
F90.0 Disturbance of activity and attention	0.001	0.998	0.000
F91.9 Conduct disorder, unspecified	0.001	0.998	0.000
F91.8 Other conduct disorders	0.001	0.998	0.000
F91.3 Oppositional defiant disorder	0.001	0.998	0.000
F91.2 Socialised conduct disorder	0.001	0.998	0.000
F91.1 Unsocialised conduct disorder	0.001	0.998	0.000
F91.0 Conduct disorder confined to the family context	0.001	0.998	0.000
F92.9 Mixed disorder of conduct and emotions, unspecified	0.001	0.998	0.000
F92.8 Other mixed disorders of conduct and emotions	0.001	0.998	0.000
F92.0 Depressive conduct disorder	0.001	0.998	0.000
F93.9 Childhood emotional disorder, unspecified	0.001	0.998	0.000
F93.8 Other childhood emotional disorders	0.001	0.998	0.000
F93.3 Sibling rivalry disorder	0.001	0.998	0.000
F93.2 Social anxiety disorder of childhood	0.001	0.998	0.000
F93.1 Phobic anxiety disorder of childhood	0.001	0.998	0.000
F93.0 Separation anxiety disorder of childhood	0.001	0.998	0.000
F94.9 Childhood disorder of social functioning, unspecified	0.001	0.998	0.000
F94.8 Other childhood disorders of social functioning	0.001	0.998	0.000
F94.2 Disinhibited attachment disorder of childhood	0.001	0.998	0.000
F94.1 Reactive attachment disorder of childhood	0.001	0.998	0.000
F94.0 Elective mutism	0.001	0.998	0.000
F95.9 Tic disorder, unspecified	0.001	0.998	0.000
F95.8 Other tic disorders	0.001	0.998	0.000
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]	0.001	0.998	0.000
F95.1 Chronic motor or vocal tic disorder	0.001	0.998	0.000
F95.0 Transient tic disorder	0.001	0.998	0.000
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.998	0.000
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.998	0.000
F98.6 Cluttering	0.001	0.998	0.000
F98.5 Stuttering [stammering]	0.001	0.998	0.000
F98.4 Stereotyped movement disorders	0.001	0.998	0.000
F98.3 Pica of infancy and childhood	0.001	0.998	0.000
F98.2 Feeding disorder of infancy and childhood	0.001	0.998	0.000
F98.1 Nonorganic encopresis	0.001	0.998	0.000
F98.0 Nonorganic enuresis	0.001	0.998	0.000
G82.1 Spastic paraplegia	0.000	0.998	0.002
F12 Mental and behavioural disorders due to use of cannabinoids	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.001	0.998	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.001	0.998	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.001	0.998	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.001	0.998	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.001	0.998	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.001	0.998	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.001	0.998	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.001	0.998	0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)	0.001	0.998	0.000
F70.8 Mild mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)	0.001	0.998	0.000
F71.8 Moderate mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
F72.9 Severe mental retardation (Without mention of impairment of behaviour)	0.001	0.998	0.000
F72.8 Severe mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
F73.9 Profound mental retardation (Without mention of impairment of behaviour)	0.001	0.998	0.000
F73.8 Profound mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
F78.9 Other mental retardation (Without mention of impairment of behaviour)	0.001	0.998	0.000
F78.8 Other mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
F12.2 Dependence syndrome	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.998	0.000
L73.9 Follicular disorder, unspecified	0.000	0.998	0.002
V18.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
M07.68 Other enteropathic arthropathies (Other)	0.001	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.998	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.001	0.998	0.000
M49.4 Neuropathic spondylopathy	0.001	0.998	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
M49.2 Enterobacterial spondylitis	0.001	0.998	0.000
M49.1 Brucella spondylitis	0.001	0.998	0.000
M49.0 Tuberculosis of spine	0.001	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.001
F19.9 Unspecified mental and behavioural disorder	0.001	0.998	0.000
F19.8 Other mental and behavioural disorders	0.001	0.998	0.000
F19.7 Residual and late-onset psychotic disorder	0.001	0.998	0.000
F19.6 Amnesic syndrome	0.001	0.998	0.000
F19.5 Psychotic disorder	0.001	0.998	0.000
F19.4 Withdrawal state with delirium	0.001	0.998	0.000
F19.3 Withdrawal state	0.001	0.998	0.000
F19.0 Acute intoxication	0.001	0.998	0.000
F79.8 Unspecified mental retardation (Other impairments of behaviour)	0.001	0.998	0.000
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.001	0.998	0.000
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.001	0.998	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.998	0.000
V18.4 Driver injured in traffic accident	0.001	0.998	0.000
V18.5 Passenger injured in traffic accident	0.001	0.998	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.002	0.998	0.000
M10.06 Idiopathic gout (Lower leg)	0.001	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
M10.0 Idiopathic gout	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.002	0.998	0.000
V18.3 Person injured while boarding or alighting	0.001	0.998	0.000
V19.8 Pedal cyclist [any] injured in other specified transport accidents	0.001	0.998	0.000
F89 Unspecified disorder of psychological development	0.001	0.998	0.000
F88 Other disorders of psychological development	0.001	0.998	0.000
F83 Mixed specific developmental disorders	0.001	0.998	0.000
F82 Specific developmental disorder of motor function	0.001	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
Z30.3 Menstrual extraction	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations