TreeWAS – Variant ID: rs917727

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.50 Fracture of lower end of radius (closed)	0.000	0.000	1.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.000	1.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.000	1.000
S52.5 Fracture of lower end of radius	0.000	0.001	0.999
S52 Fracture of forearm	0.000	0.001	0.999
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.005	0.995
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.058	0.942
M81.9 Osteoporosis, unspecified	0.000	0.080	0.920
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.143	0.857
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.166	0.834
S52.8 Fracture of other parts of forearm	0.000	0.222	0.778
S52.4 Fracture of shafts of both ulna and radius	0.000	0.224	0.776
S52.3 Fracture of shaft of radius	0.000	0.244	0.756
S52.7 Multiple fractures of forearm	0.000	0.281	0.719
S52.9 Fracture of forearm, part unspecified	0.000	0.284	0.716
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.308	0.692
S52.51 Fracture of lower end of radius (open)	0.000	0.309	0.691
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.341	0.659
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.341	0.659
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.341	0.659
S52.0 Fracture of upper end of ulna	0.000	0.355	0.645
S52.1 Fracture of upper end of radius	0.000	0.359	0.641
M81 Osteoporosis without pathological fracture	0.000	0.369	0.631
S52.80 Fracture of other parts of forearm (closed)	0.000	0.380	0.620
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.384	0.616
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.391	0.609
M81.98 Osteoporosis, unspecified (Other)	0.000	0.407	0.593
S52.30 Fracture of shaft of radius (closed)	0.000	0.418	0.582
S52.81 Fracture of other parts of forearm (open)	0.000	0.442	0.558
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.444	0.556
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.450	0.549
S52.31 Fracture of shaft of radius (open)	0.000	0.458	0.542
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.476	0.523
S52.70 Multiple fractures of forearm (closed)	0.000	0.481	0.519
S52.01 Fracture of upper end of ulna (open)	0.000	0.484	0.516
S52.71 Multiple fractures of forearm (open)	0.000	0.484	0.516
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.486	0.513
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.486	0.513
S52.2 Fracture of shaft of ulna	0.000	0.489	0.510
M81.4 Drug-induced osteoporosis	0.000	0.506	0.494
S82.00 Fracture of patella (closed)	0.000	0.520	0.480
M81.2 Osteoporosis of disuse	0.000	0.521	0.479
S82.0 Fracture of patella	0.000	0.524	0.476
S82 Fracture of lower leg, including ankle	0.000	0.527	0.473
M81.0 Postmenopausal osteoporosis	0.000	0.538	0.462
S52.11 Fracture of upper end of radius (open)	0.000	0.541	0.459
S82.8 Fractures of other parts of lower leg	0.000	0.544	0.456
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.545	0.454
M81.8 Other osteoporosis	0.000	0.547	0.453
M81.6 Localised osteoporosis [Lequesne]	0.000	0.547	0.453
M81.5 Idiopathic osteoporosis	0.000	0.547	0.453
M81.1 Postoophorectomy osteoporosis	0.000	0.547	0.453
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.551	0.449
S82.5 Fracture of medial malleolus	0.000	0.567	0.433
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.576	0.424
S82.1 Fracture of upper end of tibia	0.000	0.589	0.411
S82.50 Fracture of medial malleolus (closed)	0.000	0.593	0.407
S82.01 Fracture of patella (open)	0.000	0.616	0.384
S52.10 Fracture of upper end of radius (closed)	0.000	0.616	0.384
S82.7 Multiple fractures of lower leg	0.000	0.622	0.378
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.630	0.370
S82.10 Fracture of upper end of tibia (closed)	0.000	0.635	0.365
S82.6 Fracture of lateral malleolus	0.000	0.637	0.363
S82.4 Fracture of fibula alone	0.000	0.638	0.362
S82.3 Fracture of lower end of tibia	0.000	0.642	0.358
M81.48 Drug-induced osteoporosis (Other)	0.000	0.646	0.354
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.646	0.354
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.646	0.354
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.646	0.354
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.646	0.354
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.646	0.354
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.646	0.354
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.646	0.354
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.656	0.344
M81.28 Osteoporosis of disuse (Other)	0.000	0.656	0.344
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.656	0.344
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.656	0.344
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.656	0.344
M81.24 Osteoporosis of disuse (Hand)	0.000	0.656	0.344
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.656	0.344
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.656	0.344
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.656	0.344
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.659	0.341
S82.9 Fracture of lower leg, part unspecified	0.000	0.661	0.339
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.668	0.331
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.668	0.331
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.668	0.331
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.668	0.331
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.668	0.331
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.668	0.331
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.668	0.331
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.668	0.331
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.668	0.331
S52.21 Fracture of shaft of ulna (open)	0.001	0.669	0.330
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.672	0.328
S82.86 Maisonneuve's fracture	0.000	0.673	0.327
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.674	0.326
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.674	0.326
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.674	0.326
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.674	0.326
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.674	0.326
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.674	0.326
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.674	0.326
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.674	0.326
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.674	0.326
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.675	0.325
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.675	0.325
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.675	0.325
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.675	0.325
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.675	0.325
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.675	0.325
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.675	0.325
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.675	0.325
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.675	0.325
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.675	0.325
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.675	0.325
M81.58 Idiopathic osteoporosis (Other)	0.000	0.675	0.325
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.675	0.325
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.675	0.325
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.675	0.325
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.675	0.325
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.675	0.325
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.675	0.325
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.675	0.325
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.675	0.325
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.675	0.325
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.675	0.325
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.675	0.325
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.675	0.325
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.675	0.325
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.675	0.325
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.675	0.325
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.675	0.325
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.675	0.325
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.675	0.325
M81.89 Other osteoporosis (Site unspecified)	0.000	0.675	0.325
M81.88 Other osteoporosis (Other)	0.000	0.675	0.325
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.675	0.325
M81.86 Other osteoporosis (Lower leg)	0.000	0.675	0.325
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.675	0.325
M81.84 Other osteoporosis (Hand)	0.000	0.675	0.325
M81.83 Other osteoporosis (Forearm)	0.000	0.675	0.325
M81.82 Other osteoporosis (Upper arm)	0.000	0.675	0.325
M81.81 Other osteoporosis (Shoulder region)	0.000	0.675	0.325
M81.80 Other osteoporosis (Multiple sites)	0.000	0.675	0.325
S82.70 Multiple fractures of lower leg (closed)	0.000	0.690	0.310
S82.51 Fracture of medial malleolus (open)	0.000	0.700	0.300
S82.11 Fracture of upper end of tibia (open)	0.000	0.702	0.298
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.704	0.296
M80-M85 Disorders of bone density and structure	0.000	0.705	0.295
S82.30 Fracture of lower end of tibia (closed)	0.000	0.713	0.287
S52.00 Fracture of upper end of ulna (closed)	0.000	0.715	0.285
S82.60 Fracture of lateral malleolus (closed)	0.000	0.715	0.285
S82.40 Fracture of fibula alone (closed)	0.000	0.717	0.283
M84 Disorders of continuity of bone	0.000	0.720	0.280
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.726	0.274
S82.71 Multiple fractures of lower leg (open)	0.000	0.729	0.271
S82.81 Fractures of other parts of lower leg (open)	0.000	0.730	0.270
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.739	0.261
S82.61 Fracture of lateral malleolus (open)	0.000	0.739	0.260
S82.41 Fracture of fibula alone (open)	0.000	0.740	0.260
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.745	0.255
S82.2 Fracture of shaft of tibia	0.000	0.754	0.246
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.757	0.243
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.757	0.243
S82.31 Fracture of lower end of tibia (open)	0.000	0.761	0.239
S52.20 Fracture of shaft of ulna (closed)	0.001	0.770	0.229
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.781	0.219
M83 Adult osteomalacia	0.000	0.783	0.217
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.795	0.205
M84.0 Malunion of fracture	0.000	0.795	0.205
M84.9 Disorder of continuity of bone, unspecified	0.000	0.799	0.201
M84.2 Delayed union of fracture	0.000	0.799	0.201
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.801	0.199
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.803	0.196
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.803	0.196
M84.3 Stress fracture, not elsewhere classified	0.000	0.804	0.196
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.805	0.195
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.806	0.194
M84.4 Pathological fracture, not elsewhere classified	0.000	0.811	0.188
M82 Osteoporosis in diseases classified elsewhere	0.001	0.822	0.177
M84.8 Other disorders of continuity of bone	0.000	0.829	0.171
M84.03 Malunion of fracture (Forearm)	0.000	0.834	0.166
M83.8 Other adult osteomalacia	0.000	0.841	0.159
M83.1 Senile osteomalacia	0.000	0.841	0.159
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.843	0.157
S82.21 Fracture of shaft of tibia (open)	0.000	0.844	0.156
M83.9 Adult osteomalacia, unspecified	0.000	0.844	0.156
M83.5 Other drug-induced osteomalacia in adults	0.000	0.844	0.156
M83.4 Aluminum bone disease	0.000	0.844	0.156
M83.3 Adult osteomalacia due to malnutrition	0.000	0.844	0.156
M83.2 Adult osteomalacia due to malabsorption	0.000	0.844	0.156
M83.0 Puerperal osteomalacia	0.000	0.844	0.156
M84.02 Malunion of fracture (Upper arm)	0.000	0.848	0.152
M84.01 Malunion of fracture (Shoulder region)	0.000	0.848	0.152
M80 Osteoporosis with pathological fracture	0.000	0.850	0.150
M84.04 Malunion of fracture (Hand)	0.000	0.850	0.150
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.853	0.147
M84.09 Malunion of fracture (Site unspecified)	0.000	0.853	0.147
M84.00 Malunion of fracture (Multiple sites)	0.000	0.853	0.147
S80-S89 Injuries to the knee and lower leg	0.000	0.855	0.145
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.856	0.144
M84.28 Delayed union of fracture (Other)	0.000	0.856	0.144
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.856	0.144
M84.26 Delayed union of fracture (Lower leg)	0.000	0.856	0.144
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.856	0.144
M84.24 Delayed union of fracture (Hand)	0.000	0.856	0.144
M84.23 Delayed union of fracture (Forearm)	0.000	0.856	0.144
M84.22 Delayed union of fracture (Upper arm)	0.000	0.856	0.144
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.856	0.144
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.856	0.144
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.856	0.144
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.856	0.144
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.856	0.144
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.856	0.144
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.856	0.144
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.856	0.144
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.856	0.144
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.856	0.144
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.856	0.144
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.856	0.144
M85 Other disorders of bone density and structure	0.000	0.857	0.143
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.859	0.141
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.859	0.141
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.859	0.141
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.859	0.141
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.859	0.141
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.859	0.141
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.859	0.141
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.859	0.141
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.859	0.141
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.864	0.136
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.865	0.135
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.865	0.135
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.865	0.135
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.865	0.135
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.865	0.135
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.865	0.135
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.865	0.135
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.865	0.135
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.865	0.135
M84.08 Malunion of fracture (Other)	0.000	0.868	0.132
Z47 Other orthopaedic follow-up care	0.000	0.870	0.130
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.872	0.127
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.872	0.127
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.872	0.127
M84.06 Malunion of fracture (Lower leg)	0.000	0.875	0.125
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.877	0.122
M84.88 Other disorders of continuity of bone (Other)	0.000	0.877	0.122
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.877	0.122
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.877	0.122
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.877	0.122
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.877	0.122
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.877	0.122
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.877	0.122
M80.8 Other osteoporosis with pathological fracture	0.000	0.877	0.123
S89 Other and unspecified injuries of lower leg	0.000	0.879	0.120
S82.20 Fracture of shaft of tibia (closed)	0.000	0.880	0.120
S62.60 Fracture of other finger (closed)	0.000	0.880	0.120
S86 Injury of muscle and tendon at lower leg level	0.000	0.882	0.118
S50-S59 Injuries to the elbow and forearm	0.000	0.882	0.118
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.883	0.117
M83.12 Senile osteomalacia (Upper arm)	0.000	0.883	0.117
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.886	0.114
M83.18 Senile osteomalacia (Other)	0.000	0.886	0.114
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.886	0.114
M83.16 Senile osteomalacia (Lower leg)	0.000	0.886	0.114
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.886	0.114
M83.14 Senile osteomalacia (Hand)	0.000	0.886	0.114
M83.13 Senile osteomalacia (Forearm)	0.000	0.886	0.114
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.886	0.114
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.886	0.114
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.886	0.114
M83.88 Other adult osteomalacia (Other)	0.000	0.886	0.114
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.886	0.114
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.886	0.114
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.886	0.114
M83.84 Other adult osteomalacia (Hand)	0.000	0.886	0.114
M83.83 Other adult osteomalacia (Forearm)	0.000	0.886	0.114
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.886	0.114
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.886	0.114
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.887	0.113
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.888	0.112
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.888	0.112
M83.08 Puerperal osteomalacia (Other)	0.000	0.888	0.112
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.888	0.112
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.888	0.112
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.888	0.112
M83.04 Puerperal osteomalacia (Hand)	0.000	0.888	0.112
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.888	0.112
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.888	0.112
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.888	0.112
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.888	0.112
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.888	0.112
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.888	0.112
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.888	0.112
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.888	0.112
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.888	0.112
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.888	0.112
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.888	0.112
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.888	0.112
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.888	0.112
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.888	0.112
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.888	0.112
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.888	0.112
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.888	0.112
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.888	0.112
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.888	0.112
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.888	0.112
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.888	0.112
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.888	0.112
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.888	0.112
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.888	0.112
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.888	0.112
M83.48 Aluminium bone disease (Other)	0.000	0.888	0.112
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.888	0.112
M83.46 Aluminium bone disease (Lower leg)	0.000	0.888	0.112
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.888	0.112
M83.44 Aluminium bone disease (Hand)	0.000	0.888	0.112
M83.43 Aluminium bone disease (Forearm)	0.000	0.888	0.112
M83.42 Aluminium bone disease (Upper arm)	0.000	0.888	0.112
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.888	0.112
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.888	0.112
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.888	0.112
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.888	0.112
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.888	0.112
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.888	0.112
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.888	0.112
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.888	0.112
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.888	0.112
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.888	0.112
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.888	0.112
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.888	0.112
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.888	0.112
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.888	0.112
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.888	0.112
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.888	0.112
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.888	0.112
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.888	0.112
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.888	0.112
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.888	0.112
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.888	0.112
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.888	0.112
M85.6 Other cyst of bone	0.000	0.890	0.110
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.892	0.108
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.892	0.108
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.892	0.108
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.894	0.105
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.895	0.105
S88 Traumatic amputation of lower leg	0.000	0.895	0.104
S87 Crushing injury of lower leg	0.000	0.895	0.104
S85 Injury of blood vessels at lower leg level	0.000	0.895	0.104
S84 Injury of nerves at lower leg level	0.000	0.895	0.104
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.897	0.103
M85.5 Aneurysmal bone cyst	0.000	0.897	0.103
M85.4 Solitary bone cyst	0.000	0.897	0.103
M85.3 Osteitis condensans	0.000	0.897	0.103
M85.1 Skeletal fluorosis	0.000	0.897	0.103
M85.9 Disorder of bone density and structure, unspecified	0.000	0.898	0.102
M85.2 Hyperostosis of skull	0.000	0.899	0.100
S89.9 Unspecified injury of lower leg	0.000	0.902	0.098
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.902	0.098
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.904	0.096
S81 Open wound of lower leg	0.000	0.905	0.095
M82.1 Osteoporosis in endocrine disorders	0.001	0.906	0.092
S89.8 Other specified injuries of lower leg	0.000	0.907	0.093
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.908	0.091
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.908	0.091
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.908	0.091
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.908	0.091
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.908	0.091
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.908	0.091
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.908	0.091
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.908	0.091
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.908	0.091
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.908	0.091
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.908	0.091
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.908	0.091
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.908	0.091
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.908	0.091
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.908	0.091
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.908	0.091
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.908	0.091
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.908	0.091
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.908	0.091
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.908	0.091
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.909	0.090
S59 Other and unspecified injuries of forearm	0.000	0.911	0.089
M85.0 Fibrous dysplasia (monostotic)	0.000	0.911	0.089
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.911	0.089
S00.8 Superficial injury of other parts of head	0.000	0.911	0.089
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.912	0.088
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.912	0.088
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.912	0.088
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.912	0.088
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.912	0.088
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.912	0.088
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.912	0.088
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.912	0.088
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.912	0.088
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.912	0.088
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.913	0.087
S89.7 Multiple injuries of lower leg	0.000	0.913	0.087
S89.1 Other specified injuries of lower leg	0.000	0.913	0.087
S89.0 Multiple injuries of lower leg	0.000	0.913	0.087
S00 Superficial injury of head	0.000	0.914	0.086
S00.1 Contusion of eyelid and periocular area	0.000	0.914	0.086
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.915	0.085
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.915	0.085
S86.0 Injury of Achilles tendon	0.000	0.915	0.085
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.915	0.085
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.915	0.085
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.915	0.085
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.000	0.915	0.085
S58 Traumatic amputation of forearm	0.000	0.915	0.085
S57 Crushing injury of forearm	0.000	0.915	0.085
Z47.9 Orthopaedic follow-up care, unspecified	0.000	0.916	0.084
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.918	0.082
S54 Injury of nerves at forearm level	0.000	0.918	0.082
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.919	0.081
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.919	0.081
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.919	0.081
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.919	0.081
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.919	0.081
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.919	0.081
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.919	0.081
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.919	0.081
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.919	0.081
S81.7 Multiple open wounds of lower leg	0.000	0.920	0.080
M85.69 Other cyst of bone (Site unspecified)	0.000	0.921	0.079
M85.66 Other cyst of bone (Lower leg)	0.000	0.921	0.079
M85.64 Other cyst of bone (Hand)	0.000	0.921	0.079
M85.63 Other cyst of bone (Forearm)	0.000	0.921	0.079
M85.62 Other cyst of bone (Upper arm)	0.000	0.921	0.079
M85.61 Other cyst of bone (Shoulder region)	0.000	0.921	0.079
M85.60 Other cyst of bone (Multiple sites)	0.000	0.921	0.079
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.921	0.079
M85.68 Other cyst of bone (Other)	0.000	0.922	0.078
S55 Injury of blood vessels at forearm level	0.000	0.922	0.078
S00.0 Superficial injury of scalp	0.000	0.922	0.078
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.922	0.077
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.922	0.077
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.922	0.077
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.922	0.077
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.922	0.077
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.922	0.077
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.922	0.077
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.922	0.077
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.922	0.077
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.922	0.077
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.922	0.077
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.922	0.077
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.922	0.077
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.922	0.077
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.922	0.077
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.922	0.077
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.922	0.077
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.922	0.077
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.922	0.077
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.922	0.077
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.922	0.077
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.922	0.077
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.922	0.077
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.922	0.077
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.922	0.077
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.922	0.077
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.922	0.077
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.922	0.077
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.922	0.077
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.922	0.077
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.924	0.076
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.925	0.075
S84.8 Injury of other nerves at lower leg level	0.000	0.925	0.075
S84.7 Injury of multiple nerves at lower leg level	0.000	0.925	0.075
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.925	0.075
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.925	0.075
S84.0 Injury of tibial nerve at lower leg level	0.000	0.925	0.075
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.925	0.075
S85.8 Injury of other blood vessels at lower leg level	0.000	0.925	0.075
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.925	0.075
S85.5 Injury of popliteal vein	0.000	0.925	0.075
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.925	0.075
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.925	0.075
S85.2 Injury of peroneal artery	0.000	0.925	0.075
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.925	0.075
S85.0 Injury of popliteal artery	0.000	0.925	0.075
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.925	0.075
S87.0 Crushing injury of knee	0.000	0.925	0.075
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.925	0.075
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.925	0.075
S88.0 Traumatic amputation at knee level	0.000	0.925	0.075
S56 Injury of muscle and tendon at forearm level	0.000	0.926	0.074
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.926	0.074
M85.18 Skeletal fluorosis (Other)	0.000	0.926	0.074
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.926	0.074
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.926	0.074
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.926	0.074
M85.14 Skeletal fluorosis (Hand)	0.000	0.926	0.074
M85.13 Skeletal fluorosis (Forearm)	0.000	0.926	0.074
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.926	0.074

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations