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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263873
log Bayes Factor = 62.514
Chromosome 6   position 31,170,713  (GRCh37) Explore rs9263873 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
R31 Unspecified haematuria
0.997 0.003 0.000
D86 Sarcoidosis
0.000 0.004 0.996
L40 Psoriasis
0.000 0.005 0.995
D60-D64 Aplastic and other anaemias
0.000 0.006 0.994
D86.9 Sarcoidosis, unspecified
0.000 0.009 0.991
D64 Other anaemias
0.000 0.009 0.991
D64.9 Anaemia, unspecified
0.000 0.013 0.987
L40.5 Arthropathic psoriasis
0.000 0.013 0.987
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.027 0.973
D69 Purpura and other haemorrhagic conditions
0.000 0.035 0.965
D69.6 Thrombocytopenia, unspecified
0.000 0.040 0.960
D50-D53 Nutritional anaemias
0.000 0.060 0.940
D86.3 Sarcoidosis of skin
0.000 0.073 0.927
D80 Immunodeficiency with predominantly antibody defects
0.000 0.075 0.925
L40.0 Psoriasis vulgaris
0.000 0.111 0.889
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.118 0.882
E03 Other hypothyroidism
0.000 0.124 0.876
D50 Iron deficiency anaemia
0.000 0.139 0.861
D66 Hereditary factor VIII deficiency
0.000 0.142 0.857
D50.9 Iron deficiency anaemia, unspecified
0.000 0.149 0.851
D55-D59 Haemolytic anaemias
0.000 0.150 0.850
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.151 0.849
D70 Agranulocytosis
0.000 0.157 0.843
D69.4 Other primary thrombocytopenia
0.000 0.171 0.829
D62 Acute posthaemorrhagic anaemia
0.000 0.175 0.825
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.177 0.823
D61 Other aplastic anaemias
0.000 0.182 0.818
D64.8 Other specified anaemias
0.000 0.183 0.817
D69.2 Other nonthrombocytopenic purpura
0.000 0.187 0.813
D69.5 Secondary thrombocytopenia
0.000 0.189 0.811
L40.1 Generalised pustular psoriasis
0.000 0.190 0.810
D84 Other immunodeficiencies
0.000 0.215 0.785
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.217 0.783
D51 Vitamin B12 deficiency anaemia
0.000 0.224 0.776
D52 Folate deficiency anaemia
0.000 0.226 0.774
L40.8 Other psoriasis
0.000 0.231 0.769
D72 Other disorders of white blood cells
0.000 0.237 0.762
E00-E07 Disorders of thyroid gland
0.000 0.241 0.759
D83 Common variable immunodeficiency
0.000 0.246 0.754
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.251 0.749
D86.0 Sarcoidosis of lung
0.000 0.253 0.747
L40.3 Pustulosis palmaris et plantaris
0.000 0.259 0.741
E05.9 Thyrotoxicosis, unspecified
0.000 0.266 0.734
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.267 0.733
D59 Acquired haemolytic anaemia
0.000 0.272 0.727
L40.4 Guttate psoriasis
0.000 0.275 0.725
D58 Other hereditary haemolytic anaemias
0.000 0.282 0.718
D81 Combined immunodeficiencies
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.287 0.713
D64.4 Congenital dyserythropoietic anaemia
0.000 0.290 0.710
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.290 0.710
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.290 0.710
D64.0 Hereditary sideroblastic anaemia
0.000 0.290 0.710
D64.3 Other sideroblastic anaemias
0.000 0.295 0.705
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.298 0.702
D86.1 Sarcoidosis of lymph nodes
0.000 0.298 0.702
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.301 0.699
D61.9 Aplastic anaemia, unspecified
0.000 0.306 0.694
D69.8 Other specified haemorrhagic conditions
0.000 0.308 0.692
E03.8 Other specified hypothyroidism
0.000 0.319 0.681
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.326 0.673
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.329 0.671
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.333 0.667
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.336 0.664
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.337 0.663
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.337 0.663
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.337 0.663
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.337 0.663
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.337 0.663
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.338 0.662
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.344 0.656
D58.0 Hereditary spherocytosis
0.000 0.345 0.655
D52.9 Folate deficiency anaemia, unspecified
0.000 0.345 0.655
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.351 0.649
D67 Hereditary factor IX deficiency
0.000 0.353 0.647
D59.1 Other autoimmune haemolytic anaemias
0.000 0.362 0.638
D84.9 Immunodeficiency, unspecified
0.000 0.362 0.638
D69.1 Qualitative platelet defects
0.000 0.364 0.636
D74 Methaemoglobinaemia
0.000 0.367 0.632
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.367 0.632
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.367 0.632
D82 Immunodeficiency associated with other major defects
0.000 0.371 0.629
E03.5 Myxoedema coma
0.000 0.372 0.628
E03.4 Atrophy of thyroid (acquired)
0.000 0.372 0.628
E03.3 Postinfectious hypothyroidism
0.000 0.372 0.628
D72.1 Eosinophilia
0.000 0.373 0.627
D84.1 Defects in the complement system
0.000 0.373 0.626
D72.8 Other specified disorders of white blood cells
0.000 0.374 0.626
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.375 0.625
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.375 0.624
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.378 0.622
D50.1 Sideropenic dysphagia
0.000 0.383 0.617
E03.1 Congenital hypothyroidism without goitre
0.000 0.383 0.617
D57 Sickle-cell disorders
0.000 0.390 0.609
D55 Anaemia due to enzyme disorders
0.000 0.390 0.609
D61.0 Constitutional aplastic anaemia
0.000 0.393 0.607
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.410 0.590
D89.3 Immune reconstitution syndrome
0.000 0.410 0.590
D61.8 Other specified aplastic anaemias
0.000 0.413 0.587
D61.3 Idiopathic aplastic anaemia
0.000 0.413 0.587
D61.2 Aplastic anaemia due to other external agents
0.000 0.413 0.587
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.417 0.583
D83.9 Common variable immunodeficiency, unspecified
0.000 0.422 0.578
D53 Other nutritional anaemias
0.000 0.426 0.574
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.428 0.572
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.432 0.568
D76.3 Other histiocytosis syndromes
0.000 0.432 0.568
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.437 0.563
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.437 0.563
D61.1 Drug-induced aplastic anaemia
0.000 0.437 0.562
D51.2 Transcobalamin II deficiency
0.000 0.444 0.556
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.444 0.556
D52.8 Other folate deficiency anaemias
0.000 0.445 0.555
D52.1 Drug-induced folate deficiency anaemia
0.000 0.445 0.555
D52.0 Dietary folate deficiency anaemia
0.000 0.445 0.555
D72.9 Disorder of white blood cells, unspecified
0.000 0.453 0.547
D72.0 Genetic anomalies of leukocytes
0.000 0.453 0.547
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.456 0.544
E00 Congenital iodine-deficiency syndrome
0.000 0.456 0.544
K90 Intestinal malabsorption
0.000 0.457 0.543
D83.8 Other common variable immunodeficiencies
0.000 0.459 0.540
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.459 0.540
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.459 0.540
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.459 0.540
E05.5 Thyroid crisis or storm
0.000 0.463 0.537
E05.4 Thyrotoxicosis factitia
0.000 0.463 0.537
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.463 0.537
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.463 0.537
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.464 0.536
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.464 0.535
D69.0 Allergic purpura
0.000 0.471 0.529
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.473 0.526
D59.8 Other acquired haemolytic anaemias
0.000 0.478 0.522
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.478 0.522
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.478 0.522
D59.3 Haemolytic-uraemic syndrome
0.000 0.478 0.522
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.478 0.522
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.478 0.522
D86.8 Sarcoidosis of other and combined sites
0.000 0.480 0.519
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.485 0.515
D58.1 Hereditary elliptocytosis
0.000 0.485 0.515
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.513
D81.8 Other combined immunodeficiencies
0.000 0.486 0.513
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.513
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.513
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.513
D81.4 Nezelof's syndrome
0.000 0.486 0.513
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.513
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.513
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.513
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.513
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.499 0.501
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.499 0.501
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.499 0.501
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.506 0.494
D89.1 Cryoglobulinaemia
0.000 0.508 0.492
D58.2 Other haemoglobinopathies
0.000 0.516 0.484
D60.8 Other acquired pure red cell aplasias
0.000 0.517 0.483
D60.1 Transient acquired pure red cell aplasia
0.000 0.517 0.483
D60.0 Chronic acquired pure red cell aplasia
0.000 0.517 0.483
E04 Other non-toxic goitre
0.000 0.521 0.479
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.526 0.474
D56 Thalassaemia
0.000 0.530 0.470
D84.8 Other specified immunodeficiencies
0.000 0.539 0.461
D74.9 Methaemoglobinaemia, unspecified
0.000 0.546 0.453
D74.8 Other methaemoglobinaemias
0.000 0.546 0.453
D74.0 Congenital methaemoglobinaemia
0.000 0.546 0.453
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.549 0.451
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.549 0.451
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.549 0.451
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.549 0.451
D82.2 Immunodeficiency with short-limbed stature
0.000 0.549 0.451
D82.0 Wiskott-Aldrich syndrome
0.000 0.549 0.451
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.550 0.450
E07 Other disorders of thyroid
0.000 0.553 0.447
K90.9 Intestinal malabsorption, unspecified
0.000 0.553 0.447
D69.9 Haemorrhagic condition, unspecified
0.001 0.554 0.446
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.556 0.443
E06 Thyroiditis
0.000 0.562 0.438
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.563 0.437
D55.8 Other anaemias due to enzyme disorders
0.000 0.563 0.437
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.563 0.437
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.563 0.437
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.563 0.437
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.563 0.437
D57.8 Other sickle-cell disorders
0.000 0.563 0.437
D57.3 Sickle-cell trait
0.000 0.563 0.437
D57.2 Double heterozygous sickling disorders
0.000 0.563 0.437
D57.1 Sickle-cell anaemia without crisis
0.000 0.563 0.437
D57.0 Sickle-cell anaemia with crisis
0.000 0.563 0.437
E04.0 Non-toxic diffuse goitre
0.000 0.564 0.436
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.573 0.427
D53.8 Other specified nutritional anaemias
0.000 0.588 0.411
D53.2 Scorbutic anaemia
0.000 0.588 0.411
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.588 0.411
D53.0 Protein deficiency anaemia
0.000 0.588 0.411
G35 Multiple sclerosis
0.000 0.599 0.401
K75 Other inflammatory liver diseases
0.000 0.600 0.400
K75.4 Autoimmune hepatitis
0.000 0.607 0.393
K70-K77 Diseases of liver
0.000 0.607 0.393
K75.8 Other specified inflammatory liver diseases
0.000 0.610 0.390
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.610 0.390
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.610 0.390
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.610 0.390
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.610 0.390
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.610 0.390
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.610 0.390
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.610 0.390
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.610 0.390
K90.3 Pancreatic steatorrhoea
0.000 0.610 0.390
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.610 0.390
K90.1 Tropical sprue
0.000 0.610 0.390
K73 Chronic hepatitis, not elsewhere classified
0.000 0.612 0.388
K70 Alcoholic liver disease
0.000 0.616 0.384
E06.3 Autoimmune thyroiditis
0.000 0.624 0.376
D50.8 Other iron deficiency anaemias
0.000 0.629 0.371
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.630 0.370
E07.8 Other specified disorders of thyroid
0.000 0.630 0.370
D82.1 Di George's syndrome
0.001 0.636 0.363
K70.9 Alcoholic liver disease, unspecified
0.000 0.645 0.355
K73.9 Chronic hepatitis, unspecified
0.000 0.646 0.354
E04.8 Other specified non-toxic goitre
0.000 0.656 0.344
E05.8 Other thyrotoxicosis
0.001 0.657 0.342
K70.1 Alcoholic hepatitis
0.000 0.659 0.341
K70.0 Alcoholic fatty liver
0.000 0.662 0.338
D56.9 Thalassaemia, unspecified
0.000 0.663 0.337
D56.8 Other thalassaemias
0.000 0.663 0.337
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.663 0.337
D56.2 Delta-beta thalassaemia
0.000 0.663 0.337
D56.0 Alpha thalassaemia
0.000 0.663 0.337
E07.1 Dyshormogenetic goitre
0.000 0.679 0.320
E07.0 Hypersecretion of calcitonin
0.000 0.679 0.320
K75.0 Abscess of liver
0.000 0.680 0.320
K72 Hepatic failure, not elsewhere classified
0.000 0.685 0.315
E06.4 Drug-induced thyroiditis
0.000 0.686 0.314
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.686 0.314
E06.0 Acute thyroiditis
0.000 0.686 0.314
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.686 0.314
D53.9 Nutritional anaemia, unspecified
0.000 0.688 0.311
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.694 0.306
E06.5 Other chronic thyroiditis
0.000 0.694 0.305
K90.8 Other intestinal malabsorption
0.000 0.700 0.300
D56.1 Beta thalassaemia
0.001 0.704 0.295
K74 Fibrosis and cirrhosis of liver
0.000 0.708 0.292
E04.2 Non-toxic multinodular goitre
0.000 0.708 0.292
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.713 0.287
K74.0 Hepatic fibrosis
0.000 0.713 0.287
K75.2 Nonspecific reactive hepatitis
0.000 0.713 0.287
K75.1 Phlebitis of portal vein
0.000 0.713 0.287
K77 Liver disorders in diseases classified elsewhere
0.000 0.718 0.282
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.722 0.278
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.722 0.278
D75 Other diseases of blood and blood-forming organs
0.000 0.727 0.273
E04.1 Non-toxic single thyroid nodule
0.000 0.735 0.265
D56.3 Thalassaemia trait
0.001 0.737 0.262
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.738 0.262
K72.0 Acute and subacute hepatic failure
0.000 0.739 0.261
D73 Diseases of spleen
0.000 0.749 0.251
K70.4 Alcoholic hepatic failure
0.000 0.761 0.239
K72.9 Hepatic failure, unspecified
0.000 0.763 0.237
K71 Toxic liver disease
0.000 0.765 0.234
E06.9 Thyroiditis, unspecified
0.000 0.771 0.228
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.772 0.228
D75.0 Familial erythrocytosis
0.000 0.777 0.223
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.778 0.222
L40-L45 Papulosquamous disorders
0.001 0.785 0.214
K72.1 Chronic hepatic failure
0.000 0.791 0.209
K74.4 Secondary biliary cirrhosis
0.000 0.791 0.209
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.791 0.209
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.797 0.202
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.797 0.202
E04.9 Non-toxic goitre, unspecified
0.000 0.805 0.195
D73.1 Hypersplenism
0.000 0.808 0.191
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.812 0.188
K74.1 Hepatic sclerosis
0.000 0.813 0.187
E06.1 Subacute thyroiditis
0.001 0.814 0.185
D73.5 Infarction of spleen
0.000 0.816 0.183
D73.2 Chronic congestive splenomegaly
0.000 0.820 0.180
K70.3 Alcoholic cirrhosis of liver
0.000 0.821 0.179
D73.3 Abscess of spleen
0.000 0.821 0.178
D73.9 Disease of spleen, unspecified
0.000 0.828 0.172
K71.9 Toxic liver disease, unspecified
0.000 0.831 0.168
K71.8 Toxic liver disease with other disorders of liver
0.000 0.831 0.168
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.831 0.168
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.831 0.168
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.831 0.168
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.831 0.168
K71.2 Toxic liver disease with acute hepatitis
0.000 0.831 0.168
K71.0 Toxic liver disease with cholestasis
0.000 0.831 0.168
D73.4 Cyst of spleen
0.001 0.842 0.158
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.844 0.156
L44 Other papulosquamous disorders
0.001 0.846 0.153
L41 Parapsoriasis
0.001 0.846 0.153
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.846 0.153
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.850 0.149
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.854 0.146
K74.5 Biliary cirrhosis, unspecified
0.000 0.858 0.142
K74.6 Other and unspecified cirrhosis of liver
0.000 0.865 0.135
D73.8 Other diseases of spleen
0.001 0.875 0.124
E27.1 Primary adrenocortical insufficiency
0.000 0.877 0.123
D75.2 Essential thrombocytosis
0.000 0.881 0.118
L42 Pityriasis rosea
0.001 0.883 0.116
L41.9 Parapsoriasis, unspecified
0.001 0.889 0.110
L41.8 Other parapsoriasis
0.001 0.889 0.110
L41.5 Retiform parapsoriasis
0.001 0.889 0.110
L41.4 Large plaque parapsoriasis
0.001 0.889 0.110
L41.3 Small plaque parapsoriasis
0.001 0.889 0.110
L41.2 Lymphomatoid papulosis
0.001 0.889 0.110
L41.1 Pityriasis lichenoides chronica
0.001 0.889 0.110
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.889 0.110
L44.9 Papulosquamous disorder, unspecified
0.001 0.889 0.110
L44.8 Other specified papulosquamous disorders
0.001 0.889 0.110
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.889 0.110
L44.3 Lichen ruber moniliformis
0.001 0.889 0.110
L44.2 Lichen striatus
0.001 0.889 0.110
L44.1 Lichen nitidus
0.001 0.889 0.110
L44.0 Pityriasis rubra pilaris
0.001 0.889 0.110
K90-K93 Other diseases of the digestive system
0.000 0.891 0.109
G36 Other acute disseminated demyelination
0.000 0.893 0.107
K75.9 Inflammatory liver disease, unspecified
0.001 0.898 0.101
E27 Other disorders of adrenal gland
0.000 0.904 0.096
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.908 0.092
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.909 0.091
E20-E35 Disorders of other endocrine glands
0.000 0.913 0.087
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.914 0.086
Chapter VI Diseases of the nervous system
0.000 0.916 0.084
E27.2 Addisonian crisis
0.000 0.918 0.082
Chapter XI Diseases of the digestive system
0.000 0.919 0.081
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.920 0.080
E07.9 Disorder of thyroid, unspecified
0.000 0.921 0.079
K74.3 Primary biliary cirrhosis
0.000 0.921 0.078
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.921 0.078
G36.9 Acute disseminated demyelination, unspecified
0.000 0.923 0.077
G36.8 Other specified acute disseminated demyelination
0.000 0.923 0.077
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.923 0.077
D75.1 Secondary polycythaemia
0.000 0.924 0.076
G62.9 Polyneuropathy, unspecified
0.000 0.924 0.076
G30-G32 Other degenerative diseases of the nervous system
0.000 0.924 0.076
G62 Other polyneuropathies
0.000 0.924 0.076
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.925 0.075
# Top node
0.000 0.925 0.075
D68 Other coagulation defects
0.000 0.925 0.075
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.925 0.075
G70-G73 Diseases of myoneural junction and muscle
0.000 0.926 0.074
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.926 0.074
M07.3 Other psoriatic arthropathies
0.001 0.927 0.072
D75.8 Other specified diseases of blood and blood-forming organs
0.001 0.928 0.072
L50-L54 Urticaria and erythema
0.000 0.928 0.072
E24 Cushing's syndrome
0.000 0.928 0.072
E20 Hypoparathyroidism
0.000 0.928 0.071
G36.0 Neuromyelitis optica [Devic]
0.000 0.929 0.071
E27.5 Adrenomedullary hyperfunction
0.000 0.931 0.069
E27.0 Other adrenocortical overactivity
0.000 0.931 0.069
L10-L14 Bullous disorders
0.000 0.931 0.068
G31.2 Degeneration of nervous system due to alcohol
0.000 0.933 0.067
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.933 0.067
G62.1 Alcoholic polyneuropathy
0.000 0.934 0.066
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.935 0.065
E34 Other endocrine disorders
0.000 0.935 0.065
L50 Urticaria
0.000 0.935 0.065
G70 Myasthenia gravis and other myoneural disorders
0.000 0.935 0.065
E25 Adrenogenital disorders
0.000 0.935 0.065
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.935 0.065
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.937 0.063
E32 Diseases of thymus
0.000 0.937 0.063
E31 Polyglandular dysfunction
0.000 0.937 0.063
E30 Disorders of puberty, not elsewhere classified
0.000 0.937 0.063
D68.6 Other Thrombophilia
0.000 0.939 0.061
G31.0 Circumscribed brain atrophy
0.000 0.939 0.061
G37 Other demyelinating diseases of central nervous system
0.000 0.939 0.060
G71 Primary disorders of muscles
0.000 0.939 0.060
E20.9 Hypoparathyroidism, unspecified
0.000 0.940 0.060
L52 Erythema nodosum
0.000 0.940 0.060
G31.8 Other specified degenerative diseases of nervous system
0.000 0.940 0.060
G62.0 Drug-induced polyneuropathy
0.000 0.941 0.059
M07.34 Other psoriatic arthropathies (Hand)
0.001 0.941 0.058
L43 Lichen planus
0.002 0.941 0.057
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.941 0.059
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.942 0.058
G70.0 Myasthenia gravis
0.000 0.943 0.057
L13 Other bullous disorders
0.000 0.943 0.057
L53 Other erythematous conditions
0.000 0.943 0.057
G00 Bacterial meningitis, not elsewhere classified
0.000 0.943 0.057
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.943 0.056
K93.1 Megacolon in Chagas' disease
0.000 0.943 0.056
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.943 0.056
G83 Other paralytic syndromes
0.000 0.944 0.056
L11 Other acantholytic disorders
0.000 0.944 0.056
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.944 0.056
E40-E46 Malnutrition
0.000 0.944 0.056
L50.9 Urticaria, unspecified
0.000 0.944 0.056
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.001 0.944 0.055
E24.9 Cushing's syndrome, unspecified
0.000 0.945 0.055
E34.9 Endocrine disorder, unspecified
0.000 0.945 0.055
E27.9 Disorder of adrenal gland, unspecified
0.000 0.945 0.055
E28 Ovarian dysfunction
0.000 0.945 0.055
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.945 0.055
G81 Hemiplegia
0.000 0.945 0.055
E24.2 Drug-induced Cushing's syndrome
0.000 0.945 0.054
G62.2 Polyneuropathy due to other toxic agents
0.000 0.946 0.054
L50.1 Idiopathic urticaria
0.000 0.946 0.054
E24.0 Pituitary-dependent Cushing's disease
0.000 0.946 0.054
G64 Other disorders of peripheral nervous system
0.000 0.946 0.054
G83.4 Cauda equina syndrome
0.000 0.946 0.054
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.946 0.053
G60 Hereditary and idiopathic neuropathy
0.000 0.947 0.053
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.947 0.053
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.947 0.053
E24.8 Other Cushing's syndrome
0.000 0.947 0.053
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.947 0.053
M07.38 Other psoriatic arthropathies (Other)
0.001 0.947 0.052
M07.33 Other psoriatic arthropathies (Forearm)
0.001 0.947 0.052
M07.32 Other psoriatic arthropathies (Upper arm)
0.001 0.947 0.052
D68.1 Hereditary factor XI deficiency
0.000 0.948 0.052
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.948 0.052
L54 Erythema in diseases classified elsewhere
0.000 0.948 0.052
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.948 0.051
E24.3 Ectopic ACTH syndrome
0.000 0.948 0.051
E24.1 Nelson's syndrome
0.000 0.948 0.051
E20.8 Other hypoparathyroidism
0.000 0.948 0.051
E20.1 Pseudohypoparathyroidism
0.000 0.948 0.051
E20.0 Idiopathic hypoparathyroidism
0.000 0.948 0.051
M07.31 Other psoriatic arthropathies (Shoulder region)
0.001 0.949 0.050
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.949 0.051
G06.0 Intracranial abscess and granuloma
0.000 0.949 0.051
E23 Hypofunction and other disorders of pituitary gland
0.000 0.950 0.050
G71.1 Myotonic disorders
0.000 0.950 0.050
D68.5 Primary Thrombophilia
0.000 0.950 0.050
G72 Other myopathies
0.000 0.950 0.050
L50.0 Allergic urticaria
0.000 0.950 0.050
L12 Pemphigoid
0.000 0.950 0.049
L14 Bullous disorders in diseases classified elsewhere
0.000 0.951 0.049
L13.0 Dermatitis herpetiformis
0.000 0.951 0.049
G70.9 Myoneural disorder, unspecified
0.000 0.951 0.049
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.951 0.048
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.951 0.048
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.001 0.951 0.048
H73.8 Other specified disorders of tympanic membrane
0.048 0.952 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.952 0.048
L91.8 Other hypertrophic disorders of skin
0.000 0.952 0.048
L11.0 Acquired keratosis follicularis
0.000 0.952 0.048
G00.9 Bacterial meningitis, unspecified
0.000 0.952 0.048
E34.5 Androgen resistance syndrome
0.000 0.953 0.047
E34.4 Constitutional tall stature
0.000 0.953 0.047
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.953 0.047
E34.1 Other hypersecretion of intestinal hormones
0.000 0.953 0.047
E28.3 Primary ovarian failure
0.000 0.953 0.047
M07.36 Other psoriatic arthropathies (Lower leg)
0.001 0.953 0.046
L50.6 Contact urticaria
0.000 0.953 0.047
L50.5 Cholinergic urticaria
0.000 0.953 0.047
L50.4 Vibratory urticaria
0.000 0.953 0.047
L50.3 Dermatographic urticaria
0.000 0.953 0.047
L50.2 Urticaria due to cold and heat
0.000 0.953 0.047
G70.8 Other specified myoneural disorders
0.000 0.953 0.047
G70.2 Congenital and developmental myasthenia
0.000 0.953 0.047
G70.1 Toxic myoneural disorders
0.000 0.953 0.047
E25.9 Adrenogenital disorder, unspecified
0.000 0.953 0.047
E25.8 Other adrenogenital disorders
0.000 0.953 0.047
E34.8 Other specified endocrine disorders
0.000 0.954 0.046
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.954 0.046
H73 Other disorders of tympanic membrane
0.046 0.954 0.000
G81.9 Hemiplegia, unspecified
0.000 0.954 0.046
G03 Meningitis due to other and unspecified causes
0.000 0.954 0.046
L10 Pemphigus
0.000 0.954 0.045
L50.8 Other urticaria
0.000 0.954 0.045
E34.0 Carcinoid syndrome
0.000 0.955 0.045
E30.9 Disorder of puberty, unspecified
0.000 0.955 0.045
E30.8 Other disorders of puberty
0.000 0.955 0.045
E30.1 Precocious puberty
0.000 0.955 0.045
E30.0 Delayed puberty
0.000 0.955 0.045
E31.9 Polyglandular dysfunction, unspecified
0.000 0.955 0.045
E31.8 Other polyglandular dysfunction
0.000 0.955 0.045
E31.1 Polyglandular hyperfunction
0.000 0.955 0.045
E31.0 Autoimmune polyglandular failure
0.000 0.955 0.045
E32.9 Disease of thymus, unspecified
0.000 0.955 0.045
E32.8 Other diseases of thymus
0.000 0.955 0.045
E32.1 Abscess of thymus
0.000 0.955 0.045
E32.0 Persistent hyperplasia of thymus
0.000 0.955 0.045
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.955 0.045
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.955 0.045
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.955 0.045
D68.4 Acquired coagulation factor deficiency
0.000 0.955 0.045
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.955 0.045
E22 Hyperfunction of pituitary gland
0.000 0.955 0.045
H73.9 Disorder of tympanic membrane, unspecified
0.045 0.955 0.000
G06.1 Intraspinal abscess and granuloma
0.000 0.955 0.045
L53.0 Toxic erythema
0.000 0.955 0.045
E29 Testicular dysfunction
0.000 0.956 0.044
G00.1 Pneumococcal meningitis
0.000 0.956 0.044
K35-K38 Diseases of appendix
0.000 0.956 0.044
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.956 0.044
G37.5 Concentric sclerosis [Balo]
0.000 0.956 0.043
G37.4 Subacute necrotising myelitis
0.000 0.956 0.043
G37.2 Central pontine myelinolysis
0.000 0.956 0.043
G37.1 Central demyelination of corpus callosum
0.000 0.956 0.043

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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