TreeWAS – Variant ID: rs9312517

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R23.3 Spontaneous ecchymoses	0.081	0.919	0.000
R23 Other skin changes	0.076	0.924	0.000
R23.4 Changes in skin texture	0.072	0.928	0.000
R23.8 Other and unspecified skin changes	0.070	0.930	0.000
R23.2 Flushing	0.061	0.939	0.000
R23.0 Cyanosis	0.057	0.943	0.000
R23.1 Pallor	0.044	0.956	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.024	0.976	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.022	0.978	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.021	0.979	0.000
R22.0 Localised swelling, mass and lump, head	0.019	0.981	0.000
R22.2 Localised swelling, mass and lump, trunk	0.017	0.983	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.016	0.984	0.000
R21 Rash and other nonspecific skin eruption	0.016	0.984	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.012	0.988	0.000
R22.1 Localised swelling, mass and lump, neck	0.012	0.988	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.011	0.989	0.000
I35.0 Aortic (valve) stenosis	0.009	0.991	0.000
I35.1 Aortic (valve) insufficiency	0.009	0.991	0.000
I35 Nonrheumatic aortic valve disorders	0.008	0.992	0.000
I35.9 Aortic valve disorder, unspecified	0.008	0.992	0.000
R20 Disturbances of skin sensation	0.006	0.993	0.001
I35.8 Other aortic valve disorders	0.006	0.994	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.006	0.994	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.006	0.994	0.000
R20.0 Anaesthesia of skin	0.005	0.994	0.001
R47.8 Other and unspecified speech disturbances	0.006	0.994	0.000
R20.3 Hyperaesthesia	0.005	0.995	0.001
R20.1 Hypoaesthesia of skin	0.005	0.995	0.001
S82.20 Fracture of shaft of tibia (closed)	0.005	0.995	0.000
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
H65 Nonsuppurative otitis media	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.000	0.996	0.004
H65.4 Other chronic nonsuppurative otitis media	0.000	0.996	0.004
N40 Hyperplasia of prostate	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.000	0.997	0.003
S00.3 Superficial injury of nose	0.003	0.997	0.000
M79.69 Pain in limb (Site unspecified)	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.000	0.997	0.003
I51.8 Other ill-defined heart diseases	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.000	0.997	0.003
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
D25.9 Leiomyoma of uterus, unspecified	0.000	0.997	0.003
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
T81.8 Other complications of procedures, not elsewhere classified	0.000	0.997	0.003
N28.1 Cyst of kidney, acquired	0.000	0.997	0.003
D12.6 Colon, unspecified	0.003	0.997	0.000
K07.6 Temporomandibular joint disorders	0.000	0.997	0.002
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
N40-N51 Diseases of male genital organs	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
D13.0 Oesophagus	0.002	0.998	0.000
H53.2 Diplopia	0.000	0.998	0.002
N44 Torsion of testis	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
N46 Male infertility	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.998	0.002
N42.1 Congestion and haemorrhage of prostate	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
N42.2 Atrophy of prostate	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
N42 Other disorders of prostate	0.002	0.998	0.000
R63.0 Anorexia	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.998	0.002
D35.1 Parathyroid gland	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
N51 Disorders of male genital organs in diseases classified elsewhere	0.002	0.998	0.000
N03.9 Unspecified	0.000	0.998	0.002
R20.2 Paraesthesia of skin	0.000	0.998	0.002
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.000	0.998	0.002
H67 Otitis media in diseases classified elsewhere	0.000	0.998	0.002
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.000	0.998	0.002
N41 Inflammatory diseases of prostate	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
N42.3 Dysplasia of prostate	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.000	0.998	0.002
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.001	0.998	0.000
N51.2 Balanitis in diseases classified elsewhere	0.001	0.998	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.001	0.998	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.001	0.998	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.998	0.002
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.998	0.002
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.001	0.998	0.000
N41.1 Chronic prostatitis	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.001
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.001
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.001
H68.1 Obstruction of Eustachian tube	0.000	0.998	0.001
H68.0 Eustachian salpingitis	0.000	0.998	0.001
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.001
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.001
H70.2 Petrositis	0.000	0.998	0.001
H70.1 Chronic mastoiditis	0.000	0.998	0.001
H70.0 Acute mastoiditis	0.000	0.998	0.001
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
N41.8 Other inflammatory diseases of prostate	0.001	0.998	0.000
N41.3 Prostatocystitis	0.001	0.998	0.000
N41.2 Abscess of prostate	0.001	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.001	0.998	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.000	0.998	0.001
S89.8 Other specified injuries of lower leg	0.001	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.001
N42.0 Calculus of prostate	0.001	0.998	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.001	0.998	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.001	0.998	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.001	0.998	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.001	0.998	0.000
O14.9 Preeclampsia, unspecified	0.001	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.999	0.001
H73 Other disorders of tympanic membrane	0.000	0.999	0.001
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.999	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
F41.9 Anxiety disorder, unspecified	0.000	0.999	0.001
R49.8 Other and unspecified voice disturbances	0.001	0.999	0.000
G44.2 Tension-type headache	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
J86.9 Pyothorax without fistula	0.000	0.999	0.001
N20.0 Calculus of kidney	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.001	0.999	0.000
N45 Orchitis and epididymitis	0.001	0.999	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.001	0.999	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.999	0.001
H72 Perforation of tympanic membrane	0.000	0.999	0.001
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
H43.1 Vitreous haemorrhage	0.001	0.999	0.000
Z04.3 Examination and observation following other accident	0.000	0.999	0.001
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.999	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
H81.0 Meniere's disease	0.001	0.999	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
S42.2 Fracture of upper end of humerus	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
N43 Hydrocele and spermatocele	0.001	0.999	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.999	0.001
H73.1 Chronic myringitis	0.000	0.999	0.001
H73.0 Acute myringitis	0.000	0.999	0.001
B35.3 Tinea pedis	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.000	0.999	0.001
Z43.3 Attention to colostomy	0.000	0.999	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
F40.2 Specific (isolated) phobias	0.000	0.999	0.001
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.999	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.999	0.001
I51.9 Heart disease, unspecified	0.000	0.999	0.001
H74 Other disorders of middle ear and mastoid	0.000	0.999	0.001
C02.1 Border of tongue	0.000	0.999	0.001
K07 Dentofacial anomalies [including malocclusion]	0.000	0.999	0.001
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
S42.21 Fracture of upper end of humerus (open)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.001	0.999	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.999	0.000
N43.4 Spermatocele	0.001	0.999	0.000
N43.2 Other hydrocele	0.001	0.999	0.000
N43.1 Infected hydrocele	0.001	0.999	0.000
N43.0 Encysted hydrocele	0.001	0.999	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.000	0.999	0.001
N81.3 Complete uterovaginal prolapse	0.000	0.999	0.001
Q61.3 Polycystic kidney, unspecified	0.000	0.999	0.001
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.999	0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.999	0.001
E23.7 Disorder of pituitary gland, unspecified	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.999	0.001
N49.2 Inflammatory disorders of scrotum	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
G12.2 Motor neuron disease	0.001	0.999	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.999	0.001
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.999	0.001
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.999	0.001
H72.8 Other perforations of tympanic membrane	0.000	0.999	0.001
K07.9 Dentofacial anomaly, unspecified	0.000	0.999	0.001
K07.8 Other dentofacial anomalies	0.000	0.999	0.001
K07.5 Dentofacial functional abnormalities	0.000	0.999	0.001
K07.0 Major anomalies of jaw size	0.000	0.999	0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M65.34 Trigger finger-Hand	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
C02.8 Overlapping lesion of tongue	0.000	0.999	0.001
C02.4 Lingual tonsil	0.000	0.999	0.001
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.999	0.001
C02.2 Ventral surface of tongue	0.000	0.999	0.001
C02.0 Dorsal surface of tongue	0.000	0.999	0.001
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.999	0.001
K86.1 Other chronic pancreatitis	0.000	0.999	0.001
H43 Disorders of vitreous body	0.001	0.999	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.999	0.000
H43.9 Disorder of vitreous body, unspecified	0.001	0.999	0.000
Q61.0 Congenital single renal cyst	0.000	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
M54.59 Low back pain (Site unspecified)	0.000	0.999	0.001
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.001	0.999	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.001	0.999	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.999	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.999	0.001
H43.2 Crystalline deposits in vitreous body	0.001	0.999	0.000
H43.0 Vitreous prolapse	0.001	0.999	0.000
Y43.3 Other antineoplastic drugs	0.000	0.999	0.001
Q25.1 Coarctation of aorta	0.001	0.999	0.000
N50 Other disorders of male genital organs	0.001	0.999	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.999	0.001
B44.1 Other pulmonary aspergillosis	0.001	0.999	0.000
F31.7 Bipolar affective disorder, currently in remission	0.001	0.999	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.999	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.999	0.001
K07.2 Anomalies of dental arch relationship	0.000	0.999	0.001
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.999	0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.999	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
H74.4 Polyp of middle ear	0.000	0.999	0.001
I51.6 Cardiovascular disease, unspecified	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
S00.8 Superficial injury of other parts of head	0.001	0.999	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
B44.9 Aspergillosis, unspecified	0.001	0.999	0.000
C32.0 Glottis	0.001	0.999	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.999	0.001
E27.8 Other specified disorders of adrenal gland	0.001	0.999	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.999	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.999	0.001
I51.5 Myocardial degeneration	0.000	0.999	0.001
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.999	0.001
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.999	0.001
I51.0 Cardiac septal defect, acquired	0.000	0.999	0.001
K07.4 Malocclusion, unspecified	0.000	0.999	0.001
M06.4 Inflammatory polyarthropathy	0.000	0.999	0.001
Q61 Cystic kidney disease	0.000	0.999	0.001
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.999	0.001
E28.3 Primary ovarian failure	0.001	0.999	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
M06.3 Rheumatoid nodule	0.000	0.999	0.001
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.999	0.001
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.999	0.001
M06.38 Rheumatoid nodule (Other)	0.000	0.999	0.001
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.999	0.001
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.999	0.001
M06.33 Rheumatoid nodule (Forearm)	0.000	0.999	0.001
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.999	0.001
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.999	0.001
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.999	0.001
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.999	0.001
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.999	0.001
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.999	0.001
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.999	0.001
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.999	0.001
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.999	0.001
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.999	0.001
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.999	0.001
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.999	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
E27.9 Disorder of adrenal gland, unspecified	0.001	0.999	0.000
E27.2 Addisonian crisis	0.001	0.999	0.000
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.999	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.000	0.999	0.001
Q61.8 Other cystic kidney diseases	0.000	0.999	0.001
Q61.5 Medullary cystic kidney	0.000	0.999	0.001
Q61.4 Renal dysplasia	0.000	0.999	0.001
Q61.1 Polycystic kidney, infantile type	0.000	0.999	0.001
Z13.9 Special screening examination, unspecified	0.000	0.999	0.001
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.999	0.000
F31 Bipolar affective disorder	0.001	0.999	0.000
G44 Other headache syndromes	0.000	0.999	0.001
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.999	0.001
M06 Other rheumatoid arthritis	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
B35.6 Tinea cruris	0.001	0.999	0.000
D32.0 Cerebral meninges	0.000	0.999	0.001
D73.0 Hyposplenism	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.001	0.999	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.999	0.001
G44.3 Chronic posttraumatic headache	0.000	0.999	0.001
G44.1 Vascular headache, not elsewhere classified	0.000	0.999	0.001
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.999	0.001
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.999	0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.999	0.001
I65.1 Occlusion and stenosis of basilar artery	0.000	0.999	0.001
M06.8 Other specified rheumatoid arthritis	0.000	0.999	0.001
M06.2 Rheumatoid bursitis	0.000	0.999	0.001
M06.1 Adult-onset Still's disease	0.000	0.999	0.001
M06.0 Seronegative rheumatoid arthritis	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
N50.9 Disorder of male genital organs, unspecified	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.999	0.001
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.001	0.999	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.999	0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.999	0.001
M06.18 Adult-onset Still's disease (Other)	0.000	0.999	0.001
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.999	0.001
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.999	0.001
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.999	0.001
M06.14 Adult-onset Still's disease (Hand)	0.000	0.999	0.001
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.999	0.001
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.999	0.001
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.999	0.001
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.999	0.001
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.999	0.001
M06.28 Rheumatoid bursitis (Other)	0.000	0.999	0.001
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.999	0.001
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.999	0.001
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.999	0.001
M06.24 Rheumatoid bursitis (Hand)	0.000	0.999	0.001
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.999	0.001
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.999	0.001
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.999	0.001
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.999	0.001
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.999	0.001
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.999	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.999	0.001
D43.2 Brain, unspecified	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.000	0.999	0.001
K51.4 Pseudopolyposis of colon	0.000	0.999	0.001
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.999	0.000
Q50.5 Embryonic cyst of broad ligament	0.001	0.999	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.999	0.000
Q50.2 Congenital torsion of ovary	0.001	0.999	0.000
Q50.1 Developmental ovarian cyst	0.001	0.999	0.000
Q50.0 Congenital absence of ovary	0.001	0.999	0.000
Q83.1 Accessory breast	0.001	0.999	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.999	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
E27.5 Adrenomedullary hyperfunction	0.001	0.999	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.001	0.999	0.000
E27.0 Other adrenocortical overactivity	0.001	0.999	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.999	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.999	0.001
N50.1 Vascular disorders of male genital organs	0.001	0.999	0.000
N50.0 Atrophy of testis	0.001	0.999	0.000
E27 Other disorders of adrenal gland	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
E24.0 Pituitary-dependent Cushing's disease	0.001	0.999	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.999	0.001
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.999	0.001
N05.9 Unspecified	0.001	0.999	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.001	0.999	0.000
E28 Ovarian dysfunction	0.001	0.999	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.001	0.999	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.999	0.001
J18.9 Pneumonia, unspecified	0.001	0.999	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.001	0.999	0.000
R48.2 Apraxia	0.001	0.999	0.000
R48.1 Agnosia	0.001	0.999	0.000
R48.0 Dyslexia and alexia	0.001	0.999	0.000
D25 Leiomyoma of uterus	0.000	0.999	0.001
C32.9 Larynx, unspecified	0.001	0.999	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.999	0.001
D35.0 Adrenal gland	0.000	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.001	0.999	0.000
H43.3 Other vitreous opacities	0.001	0.999	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.999	0.001
K83.1 Obstruction of bile duct	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.001	0.999	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
R49.2 Hypernasality and hyponasality	0.001	0.999	0.000
R49.1 Aphonia	0.001	0.999	0.000
R49 Voice disturbances	0.001	0.999	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.001	0.999	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
S02.20 Fracture of nasal bones (closed)	0.001	0.999	0.000
C82.3 Follicular lymphoma grade IIIa	0.001	0.999	0.000
D13.5 Extrahepatic bile ducts	0.001	0.999	0.000
F41.8 Other specified anxiety disorders	0.000	0.999	0.001
F41.3 Other mixed anxiety disorders	0.000	0.999	0.001
G81.1 Spastic hemiplegia	0.000	0.999	0.001
G81.0 Flaccid hemiplegia	0.000	0.999	0.001
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.999	0.001
N03.8 Other	0.000	0.999	0.001
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.999	0.001
N03.6 Dense deposit disease	0.000	0.999	0.001
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.999	0.001
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.999	0.001
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.999	0.001
N03.2 Diffuse membranous glomerulonephritis	0.000	0.999	0.001
N03.0 Minor glomerular abnormality	0.000	0.999	0.001
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
T87.4 Infection of amputation stump	0.001	0.999	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.999	0.001
R47-R49 Symptoms and signs involving speech and voice	0.001	0.999	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.999	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.999	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.999	0.001
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
S32.41 Fracture of acetabulum (open)	0.001	0.999	0.000
S42.10 Fracture of scapula (closed)	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999	0.000
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
N28.8 Other specified disorders of kidney and ureter	0.000	0.999	0.001
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
S00.5 Superficial injury of lip and oral cavity	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations