TreeWAS – Variant ID: rs9317639

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.148	0.852	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.134	0.866	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.120	0.880	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.111	0.889	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.105	0.895	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.103	0.897	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.103	0.897	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.096	0.904	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.096	0.904	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.096	0.904	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.077	0.922	0.000
M65 Synovitis and tenosynovitis	0.076	0.924	0.000
M65.1 Other infective (teno)synovitis	0.058	0.942	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.058	0.942	0.000
M65.8 Other synovitis and tenosynovitis	0.057	0.943	0.000
M65.2 Calcific tendinitis	0.055	0.945	0.000
M65.0 Abscess of tendon sheath	0.055	0.945	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.046	0.954	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.046	0.954	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.044	0.956	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.044	0.956	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.044	0.956	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.042	0.958	0.000
M65.18 Other infective (teno)synovitis (Other)	0.042	0.958	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.042	0.958	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.042	0.958	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.042	0.958	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.042	0.958	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.042	0.958	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.042	0.958	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.042	0.958	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.042	0.958	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.042	0.958	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.042	0.958	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.042	0.958	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.042	0.958	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.042	0.958	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.042	0.958	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.042	0.958	0.000
M65.3 Trigger finger	0.041	0.959	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.041	0.959	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.041	0.959	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.041	0.959	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.041	0.959	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.041	0.959	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.041	0.959	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.041	0.959	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.039	0.960	0.000
M65.08 Abscess of tendon sheath (Other)	0.039	0.960	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.039	0.960	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.039	0.960	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.039	0.960	0.000
M65.04 Abscess of tendon sheath (Hand)	0.039	0.960	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.039	0.960	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.039	0.960	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.039	0.960	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.039	0.960	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.039	0.960	0.000
M65.28 Calcific tendinitis (Other)	0.039	0.960	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.039	0.960	0.000
M65.26 Calcific tendinitis (Lower leg)	0.039	0.960	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.039	0.960	0.000
M65.24 Calcific tendinitis (Hand)	0.039	0.960	0.000
M65.23 Calcific tendinitis (Forearm)	0.039	0.960	0.000
M65.22 Calcific tendinitis (Upper arm)	0.039	0.960	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.039	0.960	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.039	0.960	0.000
M65-M68 Disorders of synovium and tendon	0.034	0.965	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.032	0.968	0.000
M65.39 Trigger finger-Site unspec	0.030	0.970	0.000
M65.38 Trigger finger-Other	0.030	0.970	0.000
M65.37 Trigger finger-Ankle/foot	0.030	0.970	0.000
M65.36 Trigger finger-Lower leg	0.030	0.970	0.000
M65.35 Trigger finger-Pelvic/thigh	0.030	0.970	0.000
M65.33 Trigger finger-Forearm	0.030	0.970	0.000
M65.32 Trigger finger-Upper arm	0.030	0.970	0.000
M65.31 Trigger finger-Shldr region	0.030	0.970	0.000
M65.30 Trigger finger-Mult sites	0.030	0.970	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.025	0.975	0.000
M66 Spontaneous rupture of synovium and tendon	0.024	0.976	0.000
Z30.2 Sterilisation	0.000	0.977	0.023
M67 Other disorders of synovium and tendon	0.020	0.980	0.000
M66.2 Spontaneous rupture of extensor tendons	0.018	0.982	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.018	0.982	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.018	0.982	0.000
M24 Other specific joint derangements	0.018	0.982	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.017	0.983	0.000
M66.4 Spontaneous rupture of other tendons	0.017	0.983	0.000
M66.3 Spontaneous rupture of flexor tendons	0.017	0.983	0.000
M66.1 Rupture of synovium	0.017	0.983	0.000
M65.34 Trigger finger-Hand	0.016	0.983	0.000
M67.1 Other contracture of tendon (sheath)	0.016	0.984	0.000
M80-M85 Disorders of bone density and structure	0.016	0.984	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.016	0.984	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.016	0.984	0.000
M86-M90 Other osteopathies	0.016	0.984	0.000
M25.9 Joint disorder, unspecified	0.016	0.984	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.015	0.985	0.000
M25 Other joint disorders, not elsewhere classified	0.015	0.985	0.000
M24.0 Loose body in joint	0.015	0.985	0.000
M24.5 Contracture of joint	0.015	0.985	0.000
M67.4 Ganglion	0.015	0.985	0.000
M24.1 Other articular cartilage disorders	0.015	0.985	0.000
M20-M25 Other joint disorders	0.015	0.985	0.000
O03.4 Incomplete, without complication	0.000	0.985	0.015
M66.0 Rupture of popliteal cyst	0.015	0.985	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.015	0.985	0.000
M67.3 Transient synovitis	0.015	0.985	0.000
M67.0 Short Achilles tendon (acquired)	0.015	0.985	0.000
M85 Other disorders of bone density and structure	0.015	0.985	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.015	0.985	0.000
M80 Osteoporosis with pathological fracture	0.015	0.985	0.000
M89 Other disorders of bone	0.014	0.985	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.014	0.986	0.000
M24.2 Disorder of ligament	0.014	0.986	0.000
K56.2 Volvulus	0.000	0.986	0.014
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.014	0.986	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.014	0.986	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.014	0.986	0.000
M84 Disorders of continuity of bone	0.014	0.986	0.000
M24.6 Ankylosis of joint	0.014	0.986	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.013	0.986	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.013	0.986	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.013	0.986	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.013	0.986	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.013	0.986	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.013	0.986	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.013	0.986	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.013	0.986	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.013	0.986	0.000
M24.02 Loose body in joint (Upper arm)	0.013	0.987	0.000
M86 Osteomyelitis	0.013	0.987	0.000
K29.1 Other acute gastritis	0.000	0.987	0.013
M89.8 Other specified disorders of bone	0.013	0.987	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.013	0.987	0.000
M85.6 Other cyst of bone	0.013	0.987	0.000
M45-M49 Spondylopathies	0.013	0.987	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.013	0.987	0.000
M24.9 Joint derangement, unspecified	0.013	0.987	0.000
M24.7 Protrusio acetabuli	0.013	0.987	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.013	0.987	0.000
M25.7 Osteophyte	0.013	0.987	0.000
M66.19 Rupture of synovium (Site unspecified)	0.012	0.987	0.000
M66.18 Rupture of synovium (Other)	0.012	0.987	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.012	0.987	0.000
M66.16 Rupture of synovium (Lower leg)	0.012	0.987	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.012	0.987	0.000
M66.14 Rupture of synovium (Hand)	0.012	0.987	0.000
M66.13 Rupture of synovium (Forearm)	0.012	0.987	0.000
M66.12 Rupture of synovium (Upper arm)	0.012	0.987	0.000
M66.11 Rupture of synovium (Shoulder region)	0.012	0.987	0.000
M66.10 Rupture of synovium (Multiple sites)	0.012	0.987	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.012	0.987	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.012	0.987	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.012	0.987	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.012	0.987	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.012	0.987	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.012	0.987	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.012	0.987	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.012	0.987	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.012	0.987	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.012	0.987	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.012	0.987	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.012	0.987	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.012	0.987	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.012	0.987	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.012	0.987	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.012	0.987	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.012	0.987	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.012	0.987	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.012	0.987	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.012	0.987	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.012	0.987	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.012	0.987	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.012	0.987	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.012	0.987	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.012	0.987	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.012	0.987	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.012	0.987	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.012	0.987	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.012	0.987	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.012	0.987	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.013	0.987	0.000
M30 Polyarteritis nodosa and related conditions	0.013	0.987	0.000
M24.57 Contracture of joint (Ankle and foot)	0.012	0.987	0.000
M24.24 Disorder of ligament (Hand)	0.012	0.988	0.000
M25.8 Other specified joint disorders	0.012	0.988	0.000
M87 Osteonecrosis	0.012	0.988	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.012	0.988	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.012	0.988	0.000
M85.0 Fibrous dysplasia (monostotic)	0.012	0.988	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.012	0.988	0.000
M24.54 Contracture of joint (Hand)	0.012	0.988	0.000
M24.56 Contracture of joint (Lower leg)	0.012	0.988	0.000
M60-M63 Disorders of muscles	0.012	0.988	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.012	0.988	0.000
H43.8 Other disorders of vitreous body	0.012	0.988	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.012	0.988	0.000
M84.0 Malunion of fracture	0.012	0.988	0.000
M83 Adult osteomalacia	0.012	0.988	0.000
M24.26 Disorder of ligament (Lower leg)	0.012	0.988	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.012	0.988	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.988	0.012
M34 Systemic sclerosis	0.012	0.988	0.000
M86.9 Osteomyelitis, unspecified	0.012	0.988	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.012	0.988	0.000
M90 Osteopathies in diseases classified elsewhere	0.012	0.988	0.000
M24.01 Loose body in joint (Shoulder region)	0.011	0.988	0.000
M67.43 Ganglion, wrist	0.011	0.988	0.000
M24.07 Loose body in joint (Ankle and foot)	0.011	0.988	0.000
M25.76 Osteophyte (Lower leg)	0.012	0.988	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.011	0.988	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.011	0.988	0.000
M89.0 Algoneurodystrophy	0.011	0.988	0.000
M89.5 Osteolysis	0.011	0.989	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.011	0.989	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.011	0.989	0.000
M25.98 Joint disorder, unspecified (Other)	0.011	0.989	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.011	0.989	0.000
M25.94 Joint disorder, unspecified (Hand)	0.011	0.989	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.011	0.989	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.011	0.989	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.011	0.989	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.011	0.989	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.011	0.989	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.011	0.989	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.011	0.989	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.011	0.989	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.011	0.989	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.011	0.989	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.011	0.989	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.011	0.989	0.000
M25.2 Flail joint	0.011	0.989	0.000
M25.1 Fistula of joint	0.011	0.989	0.000
M48 Other spondylopathies	0.011	0.989	0.000
M82 Osteoporosis in diseases classified elsewhere	0.011	0.989	0.000
M24.09 Loose body in joint (Site unspecified)	0.011	0.989	0.000
M24.08 Loose body in joint (Other)	0.011	0.989	0.000
M24.06 Loose body in joint-Lower leg	0.011	0.989	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.011	0.989	0.000
M24.04 Loose body in joint (Hand)	0.011	0.989	0.000
M24.03 Loose body in joint (Forearm)	0.011	0.989	0.000
M24.00 Loose body in joint (Multiple sites)	0.011	0.989	0.000
M85.8 Other specified disorders of bone density and structure	0.011	0.989	0.000
M24.59 Contracture of joint (Site unspecified)	0.011	0.989	0.000
M24.58 Contracture of joint (Other)	0.011	0.989	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.011	0.989	0.000
M24.53 Contracture of joint (Forearm)	0.011	0.989	0.000
M24.52 Contracture of joint (Upper arm)	0.011	0.989	0.000
M24.51 Contracture of joint (Shoulder region)	0.011	0.989	0.000
M24.50 Contracture of joint (Multiple sites)	0.011	0.989	0.000
M00-M03 Infectious arthropathies	0.011	0.989	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.011	0.989	0.000
M67.49 Ganglion, multiple sites	0.011	0.989	0.000
M67.47 Ganglion, ankle and foot	0.011	0.989	0.000
M67.45 Ganglion, hip	0.011	0.989	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.011	0.989	0.000
M24.18 Other articular cartilage disorders (Other)	0.011	0.989	0.000
M24.14 Other articular cartilage disorders (Hand)	0.011	0.989	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.011	0.989	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.011	0.989	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.011	0.989	0.000
M32 Systemic lupus erythematosus	0.011	0.989	0.000
M88 Paget's disease of bone [osteitis deformans]	0.011	0.989	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.011	0.989	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.989	0.011
M66.09 Rupture of popliteal cyst-Site unspec	0.011	0.989	0.000
M66.08 Rupture of popliteal cyst-Other	0.011	0.989	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.011	0.989	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.011	0.989	0.000
M66.04 Rupture of popliteal cyst-Hand	0.011	0.989	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.011	0.989	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.011	0.989	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.011	0.989	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.011	0.989	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.011	0.989	0.000
M89.3 Hypertrophy of bone	0.011	0.989	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.011	0.989	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.011	0.989	0.000
M85.9 Disorder of bone density and structure, unspecified	0.011	0.989	0.000
M85.5 Aneurysmal bone cyst	0.011	0.989	0.000
M85.4 Solitary bone cyst	0.011	0.989	0.000
M85.3 Osteitis condensans	0.011	0.989	0.000
M85.2 Hyperostosis of skull	0.011	0.989	0.000
M85.1 Skeletal fluorosis	0.011	0.989	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.011	0.989	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.011	0.989	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.011	0.989	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.011	0.989	0.000
M80.8 Other osteoporosis with pathological fracture	0.011	0.989	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.011	0.989	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.011	0.989	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.011	0.989	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.011	0.989	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.011	0.989	0.000
M25.71 Osteophyte (Shoulder region)	0.011	0.989	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.011	0.989	0.000
M89.6 Osteopathy after poliomyelitis	0.011	0.989	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.011	0.989	0.000
M89.2 Other disorders of bone development and growth	0.011	0.989	0.000
M89.1 Epiphyseal arrest	0.011	0.989	0.000
M24.29 Disorder of ligament (Site unspecified)	0.010	0.989	0.000
M24.28 Disorder of ligament (Other)	0.010	0.989	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.010	0.989	0.000
M24.22 Disorder of ligament (Upper arm)	0.010	0.989	0.000
M24.21 Disorder of ligament (Shoulder region)	0.010	0.989	0.000
M24.20 Disorder of ligament (Multiple sites)	0.010	0.989	0.000
M33 Dermatopolymyositis	0.010	0.989	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.010	0.989	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.010	0.989	0.000
M84.4 Pathological fracture, not elsewhere classified	0.010	0.989	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.010	0.989	0.000
M25.3 Other instability of joint	0.010	0.989	0.000
M22 Disorders of patella	0.011	0.989	0.000
M81 Osteoporosis without pathological fracture	0.010	0.989	0.000
M91-M94 Chondropathies	0.010	0.989	0.000
M87.2 Osteonecrosis due to previous trauma	0.010	0.990	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.010	0.990	0.000
M24.23 Disorder of ligament (Forearm)	0.010	0.990	0.000
M84.9 Disorder of continuity of bone, unspecified	0.010	0.990	0.000
M84.8 Other disorders of continuity of bone	0.010	0.990	0.000
M84.3 Stress fracture, not elsewhere classified	0.010	0.990	0.000
M84.2 Delayed union of fracture	0.010	0.990	0.000
M84.01 Malunion of fracture (Shoulder region)	0.010	0.990	0.000
M25.0 Haemarthrosis	0.010	0.990	0.000
M49 Spondylopathies in diseases classified elsewhere	0.010	0.990	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.010	0.990	0.000
M24.68 Ankylosis of joint (Other)	0.010	0.990	0.000
M24.66 Ankylosis of joint (Lower leg)	0.010	0.990	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.010	0.990	0.000
M24.64 Ankylosis of joint (Hand)	0.010	0.990	0.000
M24.63 Ankylosis of joint (Forearm)	0.010	0.990	0.000
M24.62 Ankylosis of joint (Upper arm)	0.010	0.990	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.010	0.990	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.010	0.990	0.000
H43 Disorders of vitreous body	0.010	0.990	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.010	0.990	0.000
K56.4 Other impaction of intestine	0.000	0.990	0.010
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.010	0.990	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.010	0.990	0.000
M25.72 Osteophyte (Upper arm)	0.010	0.990	0.000
M86.8 Other osteomyelitis	0.010	0.990	0.000
M86.6 Other chronic osteomyelitis	0.010	0.990	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.010	0.990	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.010	0.990	0.000
M86.3 Chronic multifocal osteomyelitis	0.010	0.990	0.000
M86.2 Subacute osteomyelitis	0.010	0.990	0.000
M86.1 Other acute osteomyelitis	0.010	0.990	0.000
M86.0 Acute haematogenous osteomyelitis	0.010	0.990	0.000
O03 Spontaneous abortion	0.000	0.990	0.010
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.010	0.990	0.000
M25.74 Osteophyte (Hand)	0.010	0.990	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.010	0.990	0.000
M89.88 Other specified disorders of bone (Other)	0.010	0.990	0.000
M89.84 Other specified disorders of bone (Hand)	0.010	0.990	0.000
M89.83 Other specified disorders of bone (Forearm)	0.010	0.990	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.010	0.990	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.010	0.990	0.000
M25.86 Other specified joint disorders (Lower leg)	0.010	0.990	0.000
H43.1 Vitreous haemorrhage	0.010	0.990	0.000
M60 Myositis	0.010	0.990	0.000
M85.69 Other cyst of bone (Site unspecified)	0.009	0.990	0.000
M85.68 Other cyst of bone (Other)	0.009	0.990	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.009	0.990	0.000
M85.66 Other cyst of bone (Lower leg)	0.009	0.990	0.000
M85.64 Other cyst of bone (Hand)	0.009	0.990	0.000
M85.63 Other cyst of bone (Forearm)	0.009	0.990	0.000
M85.62 Other cyst of bone (Upper arm)	0.009	0.990	0.000
M85.61 Other cyst of bone (Shoulder region)	0.009	0.990	0.000
M85.60 Other cyst of bone (Multiple sites)	0.009	0.990	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.010	0.990	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.010	0.990	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.010	0.990	0.000
M47 Spondylosis	0.010	0.990	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.009	0.990	0.000
M89.9 Disorder of bone, unspecified	0.010	0.990	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.009	0.990	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.009	0.990	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.009	0.990	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.009	0.990	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.009	0.990	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.009	0.990	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.009	0.990	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.009	0.990	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.009	0.990	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.009	0.990	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.009	0.990	0.000
M24.79 Protrusio acetabuli-Site unspec	0.009	0.990	0.000
M24.78 Protrusio acetabuli-Other	0.009	0.990	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.009	0.990	0.000
M24.76 Protrusio acetabuli-Lower leg	0.009	0.990	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.009	0.990	0.000
M24.74 Protrusio acetabuli-Hand	0.009	0.990	0.000
M24.73 Protrusio acetabuli-Forearm	0.009	0.990	0.000
M24.72 Protrusio acetabuli-Upper arm	0.009	0.990	0.000
M24.71 Protrusio acetabuli-Shldr region	0.009	0.990	0.000
M24.70 Protrusio acetabuli-Mult sites	0.009	0.990	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.009	0.990	0.000
M24.98 Joint derangement, unspecified (Other)	0.009	0.990	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.009	0.990	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.009	0.990	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.009	0.990	0.000
M24.94 Joint derangement, unspecified (Hand)	0.009	0.990	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.009	0.990	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.009	0.990	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.009	0.990	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.009	0.990	0.000
M25.79 Osteophyte (Site unspecified)	0.009	0.990	0.000
M25.73 Osteophyte (Forearm)	0.009	0.990	0.000
M25.70 Osteophyte (Multiple sites)	0.009	0.990	0.000
M87.8 Other osteonecrosis	0.009	0.991	0.000
M25.88 Other specified joint disorders (Other)	0.009	0.991	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.009	0.991	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.009	0.991	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.009	0.991	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.009	0.991	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.009	0.991	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.009	0.991	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.009	0.991	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.009	0.991	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.009	0.991	0.000
M30.2 Juvenile polyarteritis	0.009	0.991	0.000
M30.0 Polyarteritis nodosa	0.009	0.991	0.000
M35 Other systemic involvement of connective tissue	0.009	0.991	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.009	0.991	0.000
M34.8 Other forms of systemic sclerosis	0.009	0.991	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.009	0.991	0.000
M25.84 Other specified joint disorders (Hand)	0.009	0.991	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.009	0.991	0.000
M48.0 Spinal stenosis	0.009	0.991	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.009	0.991	0.000
M25.83 Other specified joint disorders (Forearm)	0.009	0.991	0.000
M25.82 Other specified joint disorders (Upper arm)	0.009	0.991	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.009	0.991	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.009	0.991	0.000
M87.3 Other secondary osteonecrosis	0.009	0.991	0.000
M87.1 Osteonecrosis due to drugs	0.009	0.991	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.009	0.991	0.000
M40-M43 Deforming dorsopathies	0.009	0.991	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.009	0.991	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.009	0.991	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.009	0.991	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.009	0.991	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.009	0.991	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.009	0.991	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.009	0.991	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.009	0.991	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.009	0.991	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.009	0.991	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.009	0.991	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.009	0.991	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.009	0.991	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.009	0.991	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.009	0.991	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.009	0.991	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.009	0.991	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.009	0.991	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.009	0.991	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.009	0.991	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.009	0.991	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.009	0.991	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.009	0.991	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.009	0.991	0.000
M22.8 Other disorders of patella	0.009	0.991	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.009	0.991	0.000
M34.1 CR(E)ST syndrome	0.009	0.991	0.000
M25.4 Effusion of joint	0.009	0.991	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.009	0.991	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.009	0.991	0.000
M61 Calcification and ossification of muscle	0.009	0.991	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.009	0.991	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.009	0.991	0.000
M84.09 Malunion of fracture (Site unspecified)	0.009	0.991	0.000
M84.08 Malunion of fracture (Other)	0.009	0.991	0.000
M84.06 Malunion of fracture (Lower leg)	0.009	0.991	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.009	0.991	0.000
M84.04 Malunion of fracture (Hand)	0.009	0.991	0.000
M84.02 Malunion of fracture (Upper arm)	0.009	0.991	0.000
M84.00 Malunion of fracture (Multiple sites)	0.009	0.991	0.000
M83.9 Adult osteomalacia, unspecified	0.009	0.991	0.000
M83.8 Other adult osteomalacia	0.009	0.991	0.000
M83.5 Other drug-induced osteomalacia in adults	0.009	0.991	0.000
M83.4 Aluminum bone disease	0.009	0.991	0.000
M83.3 Adult osteomalacia due to malnutrition	0.009	0.991	0.000
M83.2 Adult osteomalacia due to malabsorption	0.009	0.991	0.000
M83.1 Senile osteomalacia	0.009	0.991	0.000
M83.0 Puerperal osteomalacia	0.009	0.991	0.000
M90.7 Fracture of bone in neoplastic disease	0.009	0.991	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.009	0.991	0.000
M34.0 Progressive systemic sclerosis	0.009	0.991	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations