TreeWAS – Variant ID: rs9469457

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F32.9 Depressive episode, unspecified	0.000	0.986	0.014
K55-K64 Other diseases of intestines	0.014	0.986	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.013	0.987	0.000
K56.6 Other and unspecified intestinal obstruction	0.013	0.987	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.012	0.988	0.000
K60 Fissure and fistula of anal and rectal regions	0.012	0.988	0.000
K57 Diverticular disease of intestine	0.012	0.988	0.000
K61 Abscess of anal and rectal regions	0.012	0.988	0.000
Chapter XI Diseases of the digestive system	0.012	0.988	0.000
K07 Dentofacial anomalies [including malocclusion]	0.011	0.988	0.000
K60.3 Anal fistula	0.011	0.988	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.012	0.988	0.000
K07.6 Temporomandibular joint disorders	0.011	0.989	0.000
K13 Other diseases of lip and oral mucosa	0.011	0.989	0.000
K20 Oesophagitis	0.011	0.989	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.010	0.989	0.000
K61.0 Anal abscess	0.010	0.989	0.000
K02 Dental caries	0.010	0.990	0.000
K63 Other diseases of intestine	0.010	0.990	0.000
K11 Diseases of salivary glands	0.010	0.990	0.000
K56.7 Ileus, unspecified	0.010	0.990	0.000
K62 Other diseases of anus and rectum	0.010	0.990	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.010	0.990	0.000
K55 Vascular disorders of intestine	0.010	0.990	0.000
K01 Embedded and impacted teeth	0.010	0.990	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.010	0.990	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.010	0.990	0.000
K58 Irritable bowel syndrome	0.010	0.990	0.000
K65-K67 Diseases of peritoneum	0.010	0.990	0.000
K56.4 Other impaction of intestine	0.010	0.990	0.000
K56.3 Gallstone ileus	0.010	0.990	0.000
K56.1 Intussusception	0.010	0.990	0.000
K56.0 Paralytic ileus	0.010	0.990	0.000
K60.1 Chronic anal fissure	0.009	0.990	0.000
K50-K52 Noninfective enteritis and colitis	0.009	0.991	0.000
K56.2 Volvulus	0.009	0.991	0.000
F32 Depressive episode	0.001	0.991	0.009
K12 Stomatitis and related lesions	0.009	0.991	0.000
K10 Other diseases of jaws	0.009	0.991	0.000
K09 Cysts of oral region, not elsewhere classified	0.009	0.991	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.009	0.991	0.000
K03 Other diseases of hard tissues of teeth	0.009	0.991	0.000
K00 Disorders of tooth development and eruption	0.009	0.991	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.009	0.991	0.000
K05 Gingivitis and periodontal diseases	0.009	0.991	0.000
K60.5 Anorectal fistula	0.009	0.991	0.000
K60.4 Rectal fistula	0.009	0.991	0.000
K60.0 Acute anal fissure	0.009	0.991	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.009	0.991	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.009	0.991	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.009	0.991	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.009	0.991	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.009	0.991	0.000
K14 Diseases of tongue	0.009	0.991	0.000
K02.9 Dental caries, unspecified	0.009	0.991	0.000
K25 Gastric ulcer	0.009	0.991	0.000
K35-K38 Diseases of appendix	0.009	0.991	0.000
K62.1 Rectal polyp	0.009	0.991	0.000
K63.2 Fistula of intestine	0.009	0.991	0.000
K61.4 Intrasphincteric abscess	0.009	0.991	0.000
K61.3 Ischiorectal abscess	0.009	0.991	0.000
K61.2 Anorectal abscess	0.009	0.991	0.000
K61.1 Rectal abscess	0.009	0.991	0.000
K11.5 Sialolithiasis	0.009	0.991	0.000
K07.9 Dentofacial anomaly, unspecified	0.008	0.991	0.000
K07.8 Other dentofacial anomalies	0.008	0.991	0.000
K07.5 Dentofacial functional abnormalities	0.008	0.991	0.000
K07.4 Malocclusion, unspecified	0.008	0.991	0.000
K07.3 Anomalies of tooth position	0.008	0.991	0.000
K07.2 Anomalies of dental arch relationship	0.008	0.991	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.008	0.991	0.000
K07.0 Major anomalies of jaw size	0.008	0.991	0.000
K62.0 Anal polyp	0.008	0.991	0.000
K13.0 Diseases of lips	0.008	0.992	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.008	0.992	0.000
K60.2 Anal fissure, unspecified	0.008	0.992	0.000
K63.8 Other specified diseases of intestine	0.008	0.992	0.000
K01.1 Impacted teeth	0.008	0.992	0.000
K62.9 Disease of anus and rectum, unspecified	0.008	0.992	0.000
K08 Other disorders of teeth and supporting structures	0.008	0.992	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.008	0.992	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.008	0.992	0.000
K13.5 Oral submucous fibrosis	0.008	0.992	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.008	0.992	0.000
K13.3 Hairy leukoplakia	0.008	0.992	0.000
K13.1 Cheek and lip biting	0.008	0.992	0.000
K65 Peritonitis	0.008	0.992	0.000
N20-N23 Urolithiasis	0.008	0.992	0.000
K63.3 Ulcer of intestine	0.008	0.992	0.000
K62.8 Other specified diseases of anus and rectum	0.008	0.992	0.000
K26 Duodenal ulcer	0.008	0.992	0.000
N23 Unspecified renal colic	0.008	0.992	0.000
K51 Ulcerative colitis	0.008	0.992	0.000
K02.8 Other dental caries	0.008	0.992	0.000
K02.5 Caries with pulp exposure	0.008	0.992	0.000
K02.4 Odontoclasia	0.008	0.992	0.000
K02.3 Arrested dental caries	0.008	0.992	0.000
K02.2 Caries of cementum	0.008	0.992	0.000
K02.1 Caries of dentin	0.008	0.992	0.000
K02.0 Caries limited to enamel	0.008	0.992	0.000
K04 Diseases of pulp and periapical tissues	0.008	0.992	0.000
K22 Other diseases of oesophagus	0.008	0.992	0.000
K70-K77 Diseases of liver	0.008	0.992	0.000
K63.4 Enteroptosis	0.008	0.992	0.000
K63.1 Perforation of intestine (nontraumatic)	0.008	0.992	0.000
K63.0 Abscess of intestine	0.008	0.992	0.000
K11.9 Disease of salivary gland, unspecified	0.007	0.992	0.000
K11.8 Other diseases of salivary glands	0.007	0.992	0.000
K11.7 Disturbances of salivary secretion	0.007	0.992	0.000
K11.6 Mucocele of salivary gland	0.007	0.992	0.000
K11.4 Fistula of salivary gland	0.007	0.992	0.000
K11.3 Abscess of salivary gland	0.007	0.992	0.000
K11.2 Sialoadenitis	0.007	0.992	0.000
K11.1 Hypertrophy of salivary gland	0.007	0.992	0.000
K11.0 Atrophy of salivary gland	0.007	0.992	0.000
K66 Other disorders of peritoneum	0.007	0.992	0.000
N20 Calculus of kidney and ureter	0.008	0.992	0.000
K62.7 Radiation proctitis	0.007	0.992	0.000
K62.6 Ulcer of anus and rectum	0.007	0.992	0.000
K62.4 Stenosis of anus and rectum	0.007	0.992	0.000
K62.2 Anal prolapse	0.007	0.992	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.007	0.992	0.000
K55.9 Vascular disorder of intestine, unspecified	0.007	0.992	0.000
K55.8 Other vascular disorders of intestine	0.007	0.992	0.000
K55.2 Angiodysplasia of colon	0.007	0.992	0.000
K55.1 Chronic vascular disorders of intestine	0.007	0.992	0.000
K55.0 Acute vascular disorders of intestine	0.007	0.992	0.000
K64.9 Haemorrhoids, unspecified	0.007	0.992	0.000
K64.8 Other specified haemorrhoids	0.007	0.992	0.000
K64.5 Perianal venous thrombosis	0.007	0.992	0.000
K64.4 Residual haemorrhoidal skin tags	0.007	0.992	0.000
K64.3 Fourth degree haemorrhoids	0.007	0.992	0.000
K64.2 Third degree haemorrhoids	0.007	0.992	0.000
K64.1 Second degree haemorrhoids	0.007	0.992	0.000
K64.0 First degree haemorrhoids	0.007	0.992	0.000
K01.0 Embedded teeth	0.007	0.992	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.007	0.992	0.000
K50 Crohn's disease [regional enteritis]	0.007	0.992	0.000
N21 Calculus of lower urinary tract	0.007	0.993	0.000
K40-K46 Hernia	0.007	0.993	0.000
K28 Gastrojejunal ulcer	0.007	0.993	0.000
K27 Peptic ulcer, site unspecified	0.007	0.993	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.007	0.993	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.007	0.993	0.000
K59 Other functional intestinal disorders	0.007	0.993	0.000
N21.0 Calculus in bladder	0.007	0.993	0.000
N20.0 Calculus of kidney	0.007	0.993	0.000
K35 Acute appendicitis	0.007	0.993	0.000
K65.0 Acute peritonitis	0.007	0.993	0.000
K51.9 Ulcerative colitis, unspecified	0.007	0.993	0.000
F32.8 Other depressive episodes	0.001	0.993	0.006
F32.3 Severe depressive episode with psychotic symptoms	0.001	0.993	0.006
F32.2 Severe depressive episode without psychotic symptoms	0.001	0.993	0.006
F32.1 Moderate depressive episode	0.001	0.993	0.006
F32.0 Mild depressive episode	0.001	0.993	0.006
K00.9 Disorder of tooth development, unspecified	0.007	0.993	0.000
K00.8 Other disorders of tooth development	0.007	0.993	0.000
K00.7 Teething syndrome	0.007	0.993	0.000
K00.6 Disturbances in tooth eruption	0.007	0.993	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.007	0.993	0.000
K00.4 Disturbances in tooth formation	0.007	0.993	0.000
K00.3 Mottled teeth	0.007	0.993	0.000
K00.2 Abnormalities of size and form of teeth	0.007	0.993	0.000
K00.1 Supernumerary teeth	0.007	0.993	0.000
K00.0 Anodontia	0.007	0.993	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.007	0.993	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.007	0.993	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.007	0.993	0.000
K03.6 Deposits [accretions] on teeth	0.007	0.993	0.000
K03.5 Ankylosis of teeth	0.007	0.993	0.000
K03.4 Hypercementosis	0.007	0.993	0.000
K03.3 Pathological resorption of teeth	0.007	0.993	0.000
K03.2 Erosion of teeth	0.007	0.993	0.000
K03.1 Abrasion of teeth	0.007	0.993	0.000
K03.0 Excessive attrition of teeth	0.007	0.993	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.007	0.993	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.007	0.993	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.007	0.993	0.000
K06.1 Gingival enlargement	0.007	0.993	0.000
K06.0 Gingival recession	0.007	0.993	0.000
K09.9 Cyst of oral region, unspecified	0.007	0.993	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.007	0.993	0.000
K09.2 Other cysts of jaw	0.007	0.993	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.007	0.993	0.000
K09.0 Developmental odontogenic cysts	0.007	0.993	0.000
K10.9 Disease of jaws, unspecified	0.007	0.993	0.000
K10.8 Other specified diseases of jaws	0.007	0.993	0.000
K10.3 Alveolitis of jaws	0.007	0.993	0.000
K10.2 Inflammatory conditions of jaws	0.007	0.993	0.000
K10.1 Giant cell granuloma, central	0.007	0.993	0.000
K10.0 Developmental disorders of jaws	0.007	0.993	0.000
K12.3 Oral mucositis (ulcerative)	0.007	0.993	0.000
K12.2 Cellulitis and abscess of mouth	0.007	0.993	0.000
K12.1 Other forms of stomatitis	0.007	0.993	0.000
K12.0 Recurrent oral aphthae	0.007	0.993	0.000
K05.2 Acute periodontitis	0.007	0.993	0.000
K05.6 Periodontal disease, unspecified	0.007	0.993	0.000
K05.5 Other periodontal diseases	0.007	0.993	0.000
K05.4 Periodontosis	0.007	0.993	0.000
K05.1 Chronic gingivitis	0.007	0.993	0.000
K05.0 Acute gingivitis	0.007	0.993	0.000
K22.7 Barrett's oesophagus	0.007	0.993	0.000
K05.3 Chronic periodontitis	0.007	0.993	0.000
K14.9 Disease of tongue, unspecified	0.007	0.993	0.000
K14.6 Glossodynia	0.007	0.993	0.000
K14.5 Plicated tongue	0.007	0.993	0.000
K14.4 Atrophy of tongue papillae	0.007	0.993	0.000
K14.3 Hypertrophy of tongue papillae	0.007	0.993	0.000
K14.2 Median rhomboid glossitis	0.007	0.993	0.000
K14.1 Geographic tongue	0.007	0.993	0.000
K14.0 Glossitis	0.007	0.993	0.000
K25.7 Chronic without haemorrhage or perforation	0.007	0.993	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.007	0.993	0.000
K25.5 Chronic or unspecified with perforation	0.007	0.993	0.000
K25.4 Chronic or unspecified with haemorrhage	0.007	0.993	0.000
K25.3 Acute without haemorrhage or perforation	0.007	0.993	0.000
K25.2 Acute with both haemorrhage and perforation	0.007	0.993	0.000
K25.1 Acute with perforation	0.007	0.993	0.000
K25.0 Acute with haemorrhage	0.007	0.993	0.000
K14.8 Other diseases of tongue	0.006	0.993	0.000
K38 Other diseases of appendix	0.006	0.993	0.000
K37 Unspecified appendicitis	0.006	0.993	0.000
K36 Other appendicitis	0.006	0.993	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.007	0.993	0.000
K63.9 Disease of intestine, unspecified	0.006	0.993	0.000
K22.4 Dyskinesia of oesophagus	0.006	0.993	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.006	0.994	0.000
K63.5 Polyp of colon	0.006	0.994	0.000
K81 Cholecystitis	0.006	0.994	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.006	0.994	0.000
K62.3 Rectal prolapse	0.006	0.994	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.006	0.994	0.000
N20.2 Calculus of kidney with calculus of ureter	0.006	0.994	0.000
K50.0 Crohn's disease of small intestine	0.006	0.994	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.006	0.994	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.006	0.994	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.006	0.994	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.006	0.994	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.006	0.994	0.000
K22.1 Ulcer of oesophagus	0.006	0.994	0.000
K66.0 Peritoneal adhesions	0.006	0.994	0.000
K08.3 Retained dental root	0.006	0.994	0.000
K65.9 Peritonitis, unspecified	0.006	0.994	0.000
K65.8 Other peritonitis	0.006	0.994	0.000
K41 Femoral hernia	0.006	0.994	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.006	0.994	0.000
K90-K93 Other diseases of the digestive system	0.006	0.994	0.000
K26.7 Chronic without haemorrhage or perforation	0.006	0.994	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.006	0.994	0.000
K26.5 Chronic or unspecified with perforation	0.006	0.994	0.000
K26.4 Chronic or unspecified with haemorrhage	0.006	0.994	0.000
K26.3 Acute without haemorrhage or perforation	0.006	0.994	0.000
K26.2 Acute with both haemorrhage and perforation	0.006	0.994	0.000
K26.1 Acute with perforation	0.006	0.994	0.000
K26.0 Acute with haemorrhage	0.006	0.994	0.000
K50.1 Crohn's disease of large intestine	0.006	0.994	0.000
K51.8 Other ulcerative colitis	0.006	0.994	0.000
K51.5 Mucosal proctocolitis	0.006	0.994	0.000
K51.4 Pseudopolyposis of colon	0.006	0.994	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.006	0.994	0.000
K51.2 Ulcerative (chronic) proctitis	0.006	0.994	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.006	0.994	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.006	0.994	0.000
K86 Other diseases of pancreas	0.006	0.994	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.006	0.994	0.000
K04.8 Radicular cyst	0.006	0.994	0.000
K04.6 Periapical abscess with sinus	0.006	0.994	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.006	0.994	0.000
K04.3 Abnormal hard tissue formation in pulp	0.006	0.994	0.000
K04.2 Pulp degeneration	0.006	0.994	0.000
K04.1 Necrosis of pulp	0.006	0.994	0.000
K04.0 Pulpitis	0.006	0.994	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.006	0.994	0.000
K22.5 Diverticulum of oesophagus, acquired	0.006	0.994	0.000
K22.3 Perforation of oesophagus	0.006	0.994	0.000
K22.0 Achalasia of cardia	0.006	0.994	0.000
K77 Liver disorders in diseases classified elsewhere	0.006	0.994	0.000
K75 Other inflammatory liver diseases	0.006	0.994	0.000
K73 Chronic hepatitis, not elsewhere classified	0.006	0.994	0.000
K72 Hepatic failure, not elsewhere classified	0.006	0.994	0.000
K71 Toxic liver disease	0.006	0.994	0.000
K70 Alcoholic liver disease	0.006	0.994	0.000
K31 Other diseases of stomach and duodenum	0.006	0.994	0.000
N10-N16 Renal tubulo-interstitial diseases	0.006	0.994	0.000
K66.9 Disorder of peritoneum, unspecified	0.006	0.994	0.000
K66.8 Other specified disorders of peritoneum	0.006	0.994	0.000
K66.1 Haemoperitoneum	0.006	0.994	0.000
N20.9 Urinary calculus, unspecified	0.006	0.994	0.000
K74 Fibrosis and cirrhosis of liver	0.005	0.994	0.000
F30-F39 Mood [affective] disorders	0.001	0.994	0.004
Chapter XIV Diseases of the genitourinary system	0.006	0.994	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.006	0.994	0.000
K85 Acute pancreatitis	0.006	0.994	0.000
K50.8 Other Crohn's disease	0.005	0.994	0.000
N20.1 Calculus of ureter	0.006	0.994	0.000
K04.5 Chronic apical periodontitis	0.005	0.994	0.000
N13 Obstructive and reflux uropathy	0.006	0.994	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.005	0.994	0.000
N21.8 Other lower urinary tract calculus	0.005	0.994	0.000
N21.1 Calculus in urethra	0.005	0.994	0.000
K81.1 Chronic cholecystitis	0.005	0.994	0.000
K46 Unspecified abdominal hernia	0.005	0.994	0.000
K45 Other abdominal hernia	0.005	0.994	0.000
N40-N51 Diseases of male genital organs	0.006	0.994	0.000
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.005	0.994	0.000
K23.1 Megaoesophagus in Chagas' disease	0.005	0.994	0.000
K23.0 Tuberculous oesophagitis	0.005	0.994	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.005	0.994	0.000
K27.7 Chronic without haemorrhage or perforation	0.005	0.994	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.005	0.994	0.000
K27.5 Chronic or unspecified with perforation	0.005	0.994	0.000
K27.4 Chronic or unspecified with haemorrhage	0.005	0.994	0.000
K27.3 Acute without haemorrhage or perforation	0.005	0.994	0.000
K27.2 Acute with both haemorrhage and perforation	0.005	0.994	0.000
K27.1 Acute with perforation	0.005	0.994	0.000
K27.0 Acute with haemorrhage	0.005	0.994	0.000
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.005	0.994	0.000
K28.7 Chronic without haemorrhage or perforation	0.005	0.994	0.000
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.005	0.994	0.000
K28.5 Chronic or unspecified with perforation	0.005	0.994	0.000
K28.4 Chronic or unspecified with haemorrhage	0.005	0.994	0.000
K28.3 Acute without haemorrhage or perforation	0.005	0.994	0.000
K28.2 Acute with both haemorrhage and perforation	0.005	0.994	0.000
K28.1 Acute with perforation	0.005	0.994	0.000
K28.0 Acute with haemorrhage	0.005	0.994	0.000
K22.9 Disease of oesophagus, unspecified	0.005	0.994	0.000
K35.9 Acute appendicitis, unspecified	0.005	0.994	0.000
K52 Other non-infective gastro-enteritis and colitis	0.005	0.994	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.005	0.995	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.005	0.995	0.000
K67.3 Tuberculous peritonitis	0.005	0.995	0.000
K67.2 Syphilitic peritonitis	0.005	0.995	0.000
K67.1 Gonococcal peritonitis	0.005	0.995	0.000
K67.0 Chlamydial peritonitis	0.005	0.995	0.000
K59.9 Functional intestinal disorder, unspecified	0.005	0.995	0.000
K59.8 Other specified functional intestinal disorders	0.005	0.995	0.000
K59.4 Anal spasm	0.005	0.995	0.000
K59.3 Megacolon, not elsewhere classified	0.005	0.995	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.005	0.995	0.000
K59.1 Functional diarrhoea	0.005	0.995	0.000
K82 Other diseases of gallbladder	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.005	0.995	0.000
N17-N19 Renal failure	0.005	0.995	0.000
F17.1 Harmful use	0.005	0.995	0.000
K44 Diaphragmatic hernia	0.005	0.995	0.000
K35.8 Acute appendicitis, other and unspecified	0.005	0.995	0.000
K35.3 Acute appendicitis with localized peritonitis	0.005	0.995	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.005	0.995	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.005	0.995	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.005	0.995	0.000
K05.22 Aggressive periodontitis, generalized	0.005	0.995	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.005	0.995	0.000
K42 Umbilical hernia	0.005	0.995	0.000
M25.77 Osteophyte (Ankle and foot)	0.005	0.995	0.000
K81.9 Cholecystitis, unspecified	0.005	0.995	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.005	0.995	0.000
K38.9 Disease of appendix, unspecified	0.005	0.995	0.000
K38.8 Other specified diseases of appendix	0.005	0.995	0.000
K38.3 Fistula of appendix	0.005	0.995	0.000
K38.2 Diverticulum of appendix	0.005	0.995	0.000
K38.1 Appendicular concretions	0.005	0.995	0.000
K38.0 Hyperplasia of appendix	0.005	0.995	0.000
N18 Chronic renal failure	0.005	0.995	0.000
K76 Other diseases of liver	0.005	0.995	0.000
K83 Other diseases of biliary tract	0.005	0.995	0.000
K29 Gastritis and duodenitis	0.005	0.995	0.000
N13.3 Other and unspecified hydronephrosis	0.005	0.995	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.005	0.995	0.000
K40 Inguinal hernia	0.005	0.995	0.000
K22.2 Oesophageal obstruction	0.005	0.995	0.000
K43 Ventral hernia	0.005	0.995	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.005	0.995	0.000
K81.8 Other cholecystitis	0.005	0.995	0.000
K22.8 Other specified diseases of oesophagus	0.005	0.995	0.000
N25-N29 Other disorders of kidney and ureter	0.005	0.995	0.000
K04.7 Periapical abscess without sinus	0.004	0.995	0.000
N19 Unspecified renal failure	0.005	0.995	0.000
N45 Orchitis and epididymitis	0.005	0.995	0.000
K86.8 Other specified diseases of pancreas	0.004	0.995	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.004	0.995	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.004	0.995	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.004	0.995	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.004	0.995	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.004	0.995	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.004	0.995	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.004	0.995	0.000
K30 Dyspepsia	0.005	0.995	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.004	0.995	0.000
N18.9 Chronic renal failure, unspecified	0.004	0.995	0.000
K86.1 Other chronic pancreatitis	0.004	0.995	0.000
N48 Other disorders of penis	0.004	0.995	0.000
K86.9 Disease of pancreas, unspecified	0.004	0.996	0.000
K86.3 Pseudocyst of pancreas	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.004	0.996	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.004	0.996	0.000
K70.1 Alcoholic hepatitis	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.004	0.996	0.000
K71.9 Toxic liver disease, unspecified	0.004	0.996	0.000
K71.8 Toxic liver disease with other disorders of liver	0.004	0.996	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.004	0.996	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.004	0.996	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.004	0.996	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.004	0.996	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.004	0.996	0.000
K71.2 Toxic liver disease with acute hepatitis	0.004	0.996	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.004	0.996	0.000
K71.0 Toxic liver disease with cholestasis	0.004	0.996	0.000
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
K72.1 Chronic hepatic failure	0.004	0.996	0.000
K72.0 Acute and subacute hepatic failure	0.004	0.996	0.000
K73.9 Chronic hepatitis, unspecified	0.004	0.996	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.004	0.996	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.004	0.996	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.004	0.996	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.004	0.996	0.000
K75.9 Inflammatory liver disease, unspecified	0.004	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.004	0.996	0.000
K75.4 Autoimmune hepatitis	0.004	0.996	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.004	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.004	0.996	0.000
K75.1 Phlebitis of portal vein	0.004	0.996	0.000
K75.0 Abscess of liver	0.004	0.996	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.004	0.996	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
K31.6 Fistula of stomach and duodenum	0.004	0.996	0.000
K31.5 Obstruction of duodenum	0.004	0.996	0.000
K31.4 Gastric diverticulum	0.004	0.996	0.000
K31.3 Pylorospasm, not elsewhere classified	0.004	0.996	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.004	0.996	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.004	0.996	0.000
K31.0 Acute dilatation of stomach	0.004	0.996	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.004	0.996	0.000
N15 Other renal tubulo-interstitial diseases	0.004	0.996	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.004	0.996	0.000
N11 Chronic tubulo-interstitial nephritis	0.004	0.996	0.000
N10 Acute tubulo-interstitial nephritis	0.004	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.004	0.996	0.000
K74.4 Secondary biliary cirrhosis	0.004	0.996	0.000
K74.3 Primary biliary cirrhosis	0.004	0.996	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.004	0.996	0.000
K74.1 Hepatic sclerosis	0.004	0.996	0.000
K74.0 Hepatic fibrosis	0.004	0.996	0.000
F38 Other mood [affective] disorders	0.001	0.996	0.003
F34 Persistent mood [affective] disorders	0.001	0.996	0.003
F33 Recurrent depressive disorder	0.001	0.996	0.003
F30 Manic episode	0.001	0.996	0.003
F39 Unspecified mood [affective] disorder	0.001	0.996	0.003
N99-N99 Other disorders of the genitourinary system	0.004	0.996	0.000
K85.9 Acute pancreatitis, unspecified	0.004	0.996	0.000
K85.8 Other acute pancreatitis	0.004	0.996	0.000
K85.3 Drug-induced acute pancreatitis	0.004	0.996	0.000
K85.2 Alcohol-induced acute pancreatitis	0.004	0.996	0.000
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
K85.0 Idiopathic acute pancreatitis	0.004	0.996	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.004	0.996	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.004	0.996	0.000
N18.4 Chronic kidney disease, stage 4	0.004	0.996	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.004	0.996	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.004	0.996	0.000
N13.6 Pyonephrosis	0.004	0.996	0.000
N13.4 Hydroureter	0.004	0.996	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.004	0.996	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.004	0.996	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.004	0.996	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.004	0.996	0.000
K45.1 Other specified abdominal hernia with gangrene	0.004	0.996	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.004	0.996	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.004	0.996	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.004	0.996	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.004	0.996	0.000
M25.7 Osteophyte	0.004	0.996	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.004	0.996	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.004	0.996	0.000
N42 Other disorders of prostate	0.004	0.996	0.000
N46 Male infertility	0.004	0.996	0.000
N44 Torsion of testis	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.004	0.996	0.000
F31 Bipolar affective disorder	0.001	0.996	0.003
K80 Cholelithiasis	0.004	0.996	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.004	0.996	0.000
K52.3 Indeterminate colitis	0.004	0.996	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.004	0.996	0.000
K52.1 Toxic gastro-enteritis and colitis	0.004	0.996	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.004	0.996	0.000
K82.9 Disease of gallbladder, unspecified	0.004	0.996	0.000
K82.4 Cholesterolosis of gallbladder	0.004	0.996	0.000
K82.3 Fistula of gallbladder	0.004	0.996	0.000
K82.2 Perforation of gallbladder	0.004	0.996	0.000
K82.1 Hydrops of gallbladder	0.004	0.996	0.000
K82.0 Obstruction of gallbladder	0.004	0.996	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.004	0.996	0.000
K81.0 Acute cholecystitis	0.004	0.996	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations