TreeWAS – Variant ID: rs9531006

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	0.000	0.887	0.113
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.887	0.113
E04 Other non-toxic goitre	0.000	0.931	0.069
E04.9 Non-toxic goitre, unspecified	0.000	0.938	0.062
E04.0 Non-toxic diffuse goitre	0.000	0.947	0.053
E04.8 Other specified non-toxic goitre	0.000	0.950	0.050
E04.1 Non-toxic single thyroid nodule	0.000	0.958	0.042
K43 Ventral hernia	0.000	0.958	0.042
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.970	0.030
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.970	0.030
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.970	0.030
K43.4 Parastomal hernia with gangrene	0.000	0.970	0.030
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.970	0.030
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.970	0.030
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.971	0.029
K43.1 Ventral hernia with gangrene	0.000	0.972	0.028
K85.1 Biliary acute pancreatitis	0.023	0.977	0.000
K85 Acute pancreatitis	0.015	0.985	0.000
K85.9 Acute pancreatitis, unspecified	0.013	0.987	0.000
K85.0 Idiopathic acute pancreatitis	0.012	0.988	0.000
K85.8 Other acute pancreatitis	0.011	0.989	0.000
L29.9 Pruritus, unspecified	0.011	0.989	0.000
L98.0 Pyogenic granuloma	0.011	0.989	0.000
K85.3 Drug-induced acute pancreatitis	0.010	0.990	0.000
K85.2 Alcohol-induced acute pancreatitis	0.010	0.990	0.000
O14.9 Preeclampsia, unspecified	0.010	0.990	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.009	0.991	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.007	0.993	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.007	0.993	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.007	0.993	0.000
L29 Pruritus	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.007	0.993	0.000
O12.1 Gestational proteinuria	0.006	0.994	0.000
O14.2 HELLP syndrome	0.006	0.994	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O15 Eclampsia	0.006	0.994	0.000
L29.2 Pruritus vulvae	0.006	0.994	0.000
O12.0 Gestational oedema	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.006	0.994	0.000
J38.0 Paralysis of vocal cords and larynx	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
O14.1 Severe preeclampsia	0.006	0.994	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
L29.8 Other pruritus	0.006	0.994	0.000
L29.0 Pruritus ani	0.006	0.994	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
C90.0 Multiple myeloma	0.000	0.995	0.005
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
F60.9 Personality disorder, unspecified	0.000	0.995	0.005
L29.1 Pruritus scroti	0.005	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.995	0.005
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
J86.9 Pyothorax without fistula	0.000	0.995	0.005
O15.9 Eclampsia, unspecified as to time period	0.005	0.995	0.000
O15.2 Eclampsia in the puerperium	0.005	0.995	0.000
O15.1 Eclampsia in labour	0.005	0.995	0.000
O15.0 Eclampsia in pregnancy	0.005	0.995	0.000
L29.3 Anogenital pruritus, unspecified	0.004	0.995	0.000
E00-E07 Disorders of thyroid gland	0.000	0.996	0.004
M16.7 Other secondary coxarthrosis	0.000	0.996	0.004
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.996	0.004
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
C90.2 Plasmacytoma, extramedullary	0.000	0.996	0.004
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
R40.2 Coma, unspecified	0.004	0.996	0.000
F60 Specific personality disorders	0.000	0.996	0.004
C90.1 Plasma cell leukaemia	0.000	0.996	0.004
T23.2 Burn of second degree of wrist and hand	0.000	0.997	0.003
E06 Thyroiditis	0.000	0.997	0.003
F60.7 Dependent personality disorder	0.000	0.997	0.003
F60.0 Paranoid personality disorder	0.000	0.997	0.003
F60.5 Anankastic personality disorder	0.000	0.997	0.003
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E00 Congenital iodine-deficiency syndrome	0.000	0.997	0.003
F60.8 Other specific personality disorders	0.000	0.997	0.003
C90.3 Solitary plasmacytoma	0.000	0.997	0.003
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.997	0.003
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
N13.4 Hydroureter	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
M35.3 Polymyalgia rheumatica	0.000	0.997	0.003
C85.0 Lymphosarcoma	0.000	0.997	0.003
F60.3 Emotionally unstable personality disorder	0.000	0.997	0.003
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
F60.1 Schizoid personality disorder	0.000	0.997	0.003
R59.1 Generalised enlarged lymph nodes	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.000	0.997	0.003
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.000	0.997	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.997	0.003
R23.1 Pallor	0.003	0.997	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
F60.2 Dissocial personality disorder	0.000	0.997	0.003
C62.9 Testis, unspecified	0.000	0.997	0.003
E06.1 Subacute thyroiditis	0.000	0.997	0.003
E06.4 Drug-induced thyroiditis	0.000	0.997	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.997	0.003
E06.0 Acute thyroiditis	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.997	0.003
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
N13 Obstructive and reflux uropathy	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.002
J38.4 Oedema of larynx	0.000	0.997	0.003
R23.2 Flushing	0.003	0.997	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.003	0.997	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
C88 Malignant immunoproliferative diseases	0.000	0.998	0.002
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.998	0.002
J86 Pyothorax	0.000	0.998	0.002
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.998	0.002
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
K40-K46 Hernia	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
G83.4 Cauda equina syndrome	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.998	0.002
C88.7 Other malignant immunoproliferative diseases	0.000	0.998	0.002
C88.3 Immunoproliferative small intestinal disease	0.000	0.998	0.002
C88.2 Gamma heavy chain disease	0.000	0.998	0.002
C88.1 Alpha heavy chain disease	0.000	0.998	0.002
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.998	0.002
E03.8 Other specified hypothyroidism	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.000	0.998	0.002
R23.3 Spontaneous ecchymoses	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.002
K45 Other abdominal hernia	0.000	0.998	0.002
J43.2 Centrilobular emphysema	0.000	0.998	0.002
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
N13.6 Pyonephrosis	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
E03 Other hypothyroidism	0.000	0.998	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.000	0.998	0.002
C95 Leukaemia of unspecified cell type	0.000	0.998	0.002
C95.9 Leukaemia, unspecified	0.000	0.998	0.002
J38.6 Stenosis of larynx	0.000	0.998	0.002
J86.0 Pyothorax with fistula	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.998	0.002
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
K41 Femoral hernia	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.998	0.002
X62.9 Unspecified place	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.998	0.002
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
K45.1 Other specified abdominal hernia with gangrene	0.000	0.998	0.001
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.998	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.998	0.001
N15 Other renal tubulo-interstitial diseases	0.001	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
E03.5 Myxoedema coma	0.000	0.998	0.001
E03.4 Atrophy of thyroid (acquired)	0.000	0.998	0.001
E03.3 Postinfectious hypothyroidism	0.000	0.998	0.001
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
C93 Monocytic leukaemia	0.000	0.998	0.001
Y59 Other and unspecified vaccines and biological substances	0.001	0.998	0.000
C95.7 Other leukaemia of unspecified cell type	0.000	0.998	0.001
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.998	0.001
J31.0 Chronic rhinitis	0.000	0.998	0.002
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
R23.0 Cyanosis	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
C86 Other specified types of T/NK-cell lymphoma	0.000	0.998	0.001
S32.40 Fracture of acetabulum (closed)	0.001	0.998	0.000
C81.7 Other Hodgkin's disease	0.000	0.998	0.001
C95.0 Acute leukaemia of unspecified cell type	0.000	0.998	0.001
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.998	0.001
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.998	0.001
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.998	0.001
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.998	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.998	0.001
C77.0 Lymph nodes of head, face and neck	0.001	0.999	0.000
F62.9 Enduring personality change, unspecified	0.000	0.999	0.001
N15.1 Renal and perinephric abscess	0.001	0.999	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
I82 Other venous embolism and thrombosis	0.000	0.999	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.999	0.001
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
Y47.1 Benzodiazepines	0.001	0.999	0.000
Y58.0 BCG vaccine	0.001	0.999	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.001	0.999	0.000
E07.8 Other specified disorders of thyroid	0.000	0.999	0.001
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.999	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.999	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.999	0.000
N14.0 Analgesic nephropathy	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.999	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.999	0.000
Y47.4 Bromine compounds	0.001	0.999	0.000
Y47.3 Paraldehyde	0.001	0.999	0.000
Y47.2 Chloral derivatives	0.001	0.999	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.999	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.999	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.999	0.000
Y58.5 Diphtheria vaccine	0.001	0.999	0.000
Y58.4 Tetanus vaccine	0.001	0.999	0.000
Y58.3 Plague vaccine	0.001	0.999	0.000
Y58.2 Cholera vaccine	0.001	0.999	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.999	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.999	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
I82.0 Budd-Chiari syndrome	0.000	0.999	0.001
J38.2 Nodules of vocal cords	0.000	0.999	0.001
J45.0 Predominantly allergic asthma	0.001	0.999	0.000
K62.7 Radiation proctitis	0.001	0.999	0.000
Q43.0 Meckel's diverticulum	0.000	0.999	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.999	0.001
E03.1 Congenital hypothyroidism without goitre	0.000	0.999	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.999	0.001
Y45.4 Antirheumatics	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
C94 Other leukaemias of specified cell type	0.000	0.999	0.001
Y88 Sequelae of surgical and medical care as external cause	0.000	0.999	0.001
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.999	0.001
C96.8 Histiocytic sarcoma	0.000	0.999	0.001
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.999	0.001
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.999	0.001
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.999	0.001
C96.3 True histiocytic lymphoma	0.000	0.999	0.001
C96.2 Malignant mast cell tumour	0.000	0.999	0.001
C96.1 Malignant histiocytosis	0.000	0.999	0.001
C96.0 Letterer-Siwe disease	0.000	0.999	0.001
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.999	0.000
N15.0 Balkan nephropathy	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.999	0.000
C93.9 Monocytic leukaemia, unspecified	0.000	0.999	0.001
C93.7 Other monocytic leukaemia	0.000	0.999	0.001
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.999	0.001
C93.2 Subacute monocytic leukaemia	0.000	0.999	0.001
C93.0 Acute monocytic leukaemia	0.000	0.999	0.001
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.999	0.000
Y42.7 Androgens and anabolic congeners	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
F60-F69 Disorders of adult personality and behaviour	0.000	0.999	0.001
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.999	0.001
C86.4 Blastic NK-cell lymphoma	0.000	0.999	0.001
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.999	0.001
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.999	0.001
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.999	0.001
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.999	0.001
E27.2 Addisonian crisis	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
K05.6 Periodontal disease, unspecified	0.000	0.999	0.001
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.999	0.001
Y45.5 4-Aminophenol derivatives	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
C81 Hodgkin's disease	0.000	0.999	0.001
K46 Unspecified abdominal hernia	0.000	0.999	0.001
K42 Umbilical hernia	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
C15.5 Lower third of oesophagus	0.001	0.999	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.999	0.001
T23.6 Corrosion of second degree of wrist and hand	0.000	0.999	0.001
T23.5 Corrosion of first degree of wrist and hand	0.000	0.999	0.001
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.999	0.001
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.999	0.001
C81.2 Mixed cellularity	0.000	0.999	0.001
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.999	0.001
C93.1 Chronic monocytic leukaemia	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
I82.1 Thrombophlebitis migrans	0.000	0.999	0.001
K82.2 Perforation of gallbladder	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.999	0.001
E05.5 Thyroid crisis or storm	0.000	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.000	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.999	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.999	0.001
T23.1 Burn of first degree of wrist and hand	0.000	0.999	0.001
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.999	0.001
Y45.8 Other analgesics and antipyretics	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
Y59.0 Viral vaccines	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.999	0.001
E05.8 Other thyrotoxicosis	0.000	0.999	0.001
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.999	0.001
H44.2 Degenerative myopia	0.000	0.999	0.001
I89.1 Lymphangitis	0.001	0.999	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
C15 Malignant neoplasm of oesophagus	0.001	0.999	0.000
C94.7 Other specified leukaemias	0.000	0.999	0.001
C94.5 Acute myelofibrosis	0.000	0.999	0.001
C94.3 Mast cell leukaemia	0.000	0.999	0.001
C94.2 Acute megakaryoblastic leukaemia	0.000	0.999	0.001
C94.1 Chronic erythraemia	0.000	0.999	0.001
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.999	0.001
F62.8 Other enduring personality changes	0.000	0.999	0.001
F62.1 Enduring personality change after psychiatric illness	0.000	0.999	0.001
F62.0 Enduring personality change after catastrophic experience	0.000	0.999	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.999	0.001
C62 Malignant neoplasm of testis	0.000	0.999	0.001
R40 Somnolence, stupor and coma	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
S42.20 Fracture of upper end of humerus (closed)	0.001	0.999	0.000
A69.9 Spirochaetal infection, unspecified	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
Y60.0 During surgical operation	0.000	0.999	0.001
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.999	0.001
F65 Disorders of sexual preference	0.000	0.999	0.001
F63 Habit and impulse disorders	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.999	0.001
C81.3 Lymphocytic depletion	0.000	0.999	0.001
H16.4 Corneal neovascularisation	0.001	0.999	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.999	0.001
N80.8 Other endometriosis	0.001	0.999	0.000
D09.0 Bladder	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.999	0.001
C94.4 Acute panmyelosis	0.000	0.999	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.999	0.001
H16 Keratitis	0.001	0.999	0.000
C15.8 Overlapping lesion of oesophagus	0.001	0.999	0.000
C15.2 Abdominal part of oesophagus	0.001	0.999	0.000
C15.0 Cervical part of oesophagus	0.001	0.999	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.999	0.001
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.999	0.001
H16.9 Keratitis, unspecified	0.001	0.999	0.000
I49.3 Ventricular premature depolarisation	0.001	0.999	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.999	0.001
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.001
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations