TreeWAS – Variant ID: rs9534578

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R53 Malaise and fatigue	0.000	0.943	0.057
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.010	0.990	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.010	0.990	0.000
M06.9 Rheumatoid arthritis, unspecified	0.009	0.991	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.009	0.991	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.992	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.008	0.992	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.008	0.992	0.000
Y57.8 Other drugs and medicaments	0.008	0.992	0.000
Y43.3 Other antineoplastic drugs	0.008	0.992	0.000
H71 Cholesteatoma of middle ear	0.007	0.992	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
Y57 Other and unspecified drugs and medicaments	0.007	0.993	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.007	0.993	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.007	0.993	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
K14.0 Glossitis	0.000	0.993	0.007
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
Y40.0 Penicillins	0.007	0.993	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.006	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.006	0.994	0.000
H74 Other disorders of middle ear and mastoid	0.006	0.994	0.000
Y40 Systemic antibiotics	0.006	0.994	0.000
Y57.6 Other diagnostic agents	0.006	0.994	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
H70 Mastoiditis and related conditions	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
Y54.5 Other diuretics	0.006	0.994	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.005	0.994	0.000
H66.0 Acute suppurative otitis media	0.005	0.994	0.000
H69.8 Other specified disorders of Eustachian tube	0.005	0.994	0.000
Y57.7 Vitamins, not elsewhere classified	0.005	0.994	0.000
Y57.4 Pharmaceutical excipients	0.005	0.994	0.000
Y57.3 Alcohol deterrents	0.005	0.994	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.005	0.994	0.000
Y57.1 Lipotropic drugs	0.005	0.994	0.000
Y57.0 Appetite depressants [anorectics]	0.005	0.994	0.000
H74.0 Tympanosclerosis	0.005	0.994	0.000
Y57.9 Drug or medicament, unspecified	0.005	0.994	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
H66.9 Otitis media, unspecified	0.005	0.995	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H68 Eustachian salpingitis and obstruction	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
F10.2 Dependence syndrome	0.005	0.995	0.000
H70.9 Mastoiditis, unspecified	0.005	0.995	0.000
H70.8 Other mastoiditis and related conditions	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.995	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y53.4 Other laxatives	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
Y58 Bacterial vaccines	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.005	0.995	0.000
Y54.3 Benzothiadiazine derivatives	0.005	0.995	0.000
M06 Other rheumatoid arthritis	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.005	0.995	0.000
H74.1 Adhesive middle ear disease	0.005	0.995	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
Y40.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
Y40.6 Rifamycins	0.005	0.995	0.000
Y40.5 Aminoglycosides	0.005	0.995	0.000
Y40.4 Tetracyclines	0.005	0.995	0.000
Y40.3 Macrolides	0.005	0.995	0.000
Y40.2 Chloramphenicol group	0.005	0.995	0.000
H69.9 Eustachian tube disorder, unspecified	0.005	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
Y54.7 Agents affecting calcification	0.005	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.005	0.995	0.000
Y54.0 Mineralocorticoids	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.005	0.995	0.000
H70.2 Petrositis	0.005	0.995	0.000
H70.1 Chronic mastoiditis	0.005	0.995	0.000
H70.0 Acute mastoiditis	0.005	0.995	0.000
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.995	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.004	0.995	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
L27 Dermatitis due to substances taken internally	0.004	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
Y41.0 Sulphonamides	0.004	0.996	0.000
Y49.2 Other and unspecified antidepressants	0.004	0.996	0.000
M06.3 Rheumatoid nodule	0.004	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H68.1 Obstruction of Eustachian tube	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
K14 Diseases of tongue	0.000	0.996	0.004
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
D13.1 Stomach	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
Y49.9 Psychotropic drug, unspecified	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.996	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.996	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.004	0.996	0.000
Y44.7 Plasma substitutes	0.004	0.996	0.000
Y44.6 Natural blood and blood products	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
H35.8 Other specified retinal disorders	0.000	0.996	0.004
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
Y58.0 BCG vaccine	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
M06.8 Other specified rheumatoid arthritis	0.004	0.996	0.000
M06.2 Rheumatoid bursitis	0.004	0.996	0.000
M06.1 Adult-onset Still's disease	0.004	0.996	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
Y41.5 Antiviral drugs	0.004	0.996	0.000
Y41.4 Anthelminthics	0.004	0.996	0.000
Y41.3 Other antiprotozoal drugs	0.004	0.996	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
Y41.1 Antimycobacterial drugs	0.004	0.996	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.996	0.004
M06.0 Seronegative rheumatoid arthritis	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
M06.4 Inflammatory polyarthropathy	0.003	0.996	0.000
H65.0 Acute serous otitis media	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
Y52.7 Peripheral vasodilators	0.003	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.996	0.000
Y46.8 Antispasticity drugs	0.003	0.996	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.996	0.000
Y46.5 Valproic acid	0.003	0.996	0.000
Y46.3 Deoxybarbiturates	0.003	0.996	0.000
Y46.2 Hydantoin derivatives	0.003	0.996	0.000
Y46.1 Oxazolidinediones	0.003	0.996	0.000
Y46.0 Succinimides	0.003	0.996	0.000
K14.8 Other diseases of tongue	0.000	0.996	0.004
L28.0 Lichen simplex chronicus	0.003	0.996	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.003	0.997	0.000
L27.8 Dermatitis due to other substances taken internally	0.003	0.997	0.000
L27.2 Dermatitis due to ingested food	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.997	0.003
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
L28 Lichen simplex chronicus and prurigo	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.000	0.997	0.003
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.003	0.997	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
K14.6 Glossodynia	0.000	0.997	0.003
K14.5 Plicated tongue	0.000	0.997	0.003
K14.4 Atrophy of tongue papillae	0.000	0.997	0.003
K14.3 Hypertrophy of tongue papillae	0.000	0.997	0.003
K14.2 Median rhomboid glossitis	0.000	0.997	0.003
K14.1 Geographic tongue	0.000	0.997	0.003
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
F10.0 Acute intoxication	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
L20-L30 Dermatitis and eczema	0.003	0.997	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.997	0.003
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.003	0.997	0.000
L29.8 Other pruritus	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.997	0.003
M06.19 Adult-onset Still's disease (Site unspecified)	0.003	0.997	0.000
M06.18 Adult-onset Still's disease (Other)	0.003	0.997	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.003	0.997	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.003	0.997	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.003	0.997	0.000
M06.14 Adult-onset Still's disease (Hand)	0.003	0.997	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.003	0.997	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.003	0.997	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.003	0.997	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.003	0.997	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.003	0.997	0.000
M06.28 Rheumatoid bursitis (Other)	0.003	0.997	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.003	0.997	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.003	0.997	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.003	0.997	0.000
M06.24 Rheumatoid bursitis (Hand)	0.003	0.997	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.003	0.997	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.003	0.997	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.003	0.997	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.003	0.997	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.003	0.997	0.000
D13.0 Oesophagus	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.003	0.997	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.003	0.997	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.003	0.997	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.003	0.997	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.003	0.997	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.003	0.997	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
T51.0 Ethanol	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.997	0.003
L29 Pruritus	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
L28.1 Prurigo nodularis	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
L28.2 Other prurigo	0.003	0.997	0.000
K61.0 Anal abscess	0.000	0.997	0.003
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
F10.5 Psychotic disorder	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.997	0.000
L29.2 Pruritus vulvae	0.003	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.997	0.000
H25.8 Other senile cataract	0.000	0.997	0.003
L25 Unspecified contact dermatitis	0.002	0.997	0.000
L24 Irritant contact dermatitis	0.002	0.997	0.000
L23 Allergic contact dermatitis	0.002	0.997	0.000
L21 Seborrhoeic dermatitis	0.002	0.997	0.000
L26 Exfoliative dermatitis	0.002	0.997	0.000
L22 Diaper [napkin] dermatitis	0.002	0.997	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
Y42.4 Oral contraceptives	0.002	0.997	0.000
Y42.2 Antithyroid drugs	0.002	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.002	0.997	0.000
L20 Atopic dermatitis	0.002	0.997	0.000
N32.3 Diverticulum of bladder	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
F10.6 Amnesic syndrome	0.002	0.998	0.000
F10.4 Withdrawal state with delirium	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
F10.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F10.8 Other mental and behavioural disorders	0.002	0.998	0.000
F10.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
L29.1 Pruritus scroti	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
R41.3 Other amnesia	0.000	0.998	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
D11.0 Parotid gland	0.000	0.998	0.002
K83.0 Cholangitis	0.000	0.998	0.002
D13.3 Other and unspecified parts of small intestine	0.002	0.998	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.002	0.998	0.000
L21.8 Other seborrhoeic dermatitis	0.002	0.998	0.000
L21.1 Seborrhoeic infantile dermatitis	0.002	0.998	0.000
L21.0 Seborrhoea capitis	0.002	0.998	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.002	0.998	0.000
L23.8 Allergic contact dermatitis due to other agents	0.002	0.998	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.002	0.998	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.002	0.998	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.002	0.998	0.000
L23.4 Allergic contact dermatitis due to dyes	0.002	0.998	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.002	0.998	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.002	0.998	0.000
L23.0 Allergic contact dermatitis due to metals	0.002	0.998	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.002	0.998	0.000
L24.8 Irritant contact dermatitis due to other agents	0.002	0.998	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.002	0.998	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.002	0.998	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.002	0.998	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.002	0.998	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.002	0.998	0.000
L24.2 Irritant contact dermatitis due to solvents	0.002	0.998	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.002	0.998	0.000
L24.0 Irritant contact dermatitis due to detergents	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
L30 Other dermatitis	0.002	0.998	0.000
L25.8 Unspecified contact dermatitis due to other agents	0.002	0.998	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.002	0.998	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.002	0.998	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.002	0.998	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.002	0.998	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.002	0.998	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
D13.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
D13.7 Endocrine pancreas	0.002	0.998	0.000
D13.6 Pancreas	0.002	0.998	0.000
D13.4 Liver	0.002	0.998	0.000
L20.8 Other atopic dermatitis	0.002	0.998	0.000
L20.0 Besnier's prurigo	0.002	0.998	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.998	0.002
R07.0 Pain in throat	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
J40 Bronchitis, not specified as acute or chronic	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
D13.5 Extrahepatic bile ducts	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
J69 Pneumonitis due to solids and liquids	0.000	0.998	0.002
O63.0 Prolonged first stage (of labour)	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
L30.5 Pityriasis alba	0.002	0.998	0.000
L30.4 Erythema intertrigo	0.002	0.998	0.000
L30.3 Infective dermatitis	0.002	0.998	0.000
L30.2 Cutaneous autosensitisation	0.002	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
D13.2 Duodenum	0.002	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
G93 Other disorders of brain	0.000	0.998	0.002
F10.3 Withdrawal state	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.001	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.998	0.002
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.998	0.002
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.000	0.998	0.002
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
H35 Other retinal disorders	0.000	0.998	0.002
R02 Gangrene, not elsewhere classified	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
K35 Acute appendicitis	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
J69.8 Pneumonitis due to other solids and liquids	0.000	0.998	0.001
J69.1 Pneumonitis due to oils and essences	0.000	0.998	0.001
G93.8 Other specified disorders of brain	0.000	0.998	0.002
G93.4 Encephalopathy, unspecified	0.000	0.998	0.001
H57.0 Anomalies of pupillary function	0.000	0.998	0.001
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
G93.7 Reye's syndrome	0.000	0.998	0.001
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations