TreeWAS – Variant ID: rs9557704

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G30.9 Alzheimer's disease, unspecified	0.052	0.948	0.000
G30 Alzheimer's disease	0.022	0.978	0.000
G30.8 Other Alzheimer's disease	0.016	0.983	0.000
G30.0 Alzheimer's disease with early onset	0.015	0.984	0.000
G30.1 Alzheimer's disease with late onset	0.015	0.985	0.000
I51.8 Other ill-defined heart diseases	0.014	0.986	0.000
N05.9 Unspecified	0.014	0.986	0.000
N05 Unspecified nephritic syndrome	0.014	0.986	0.000
K76.6 Portal hypertension	0.000	0.986	0.014
N05.1 Focal and segmental glomerular lesions	0.013	0.987	0.000
K76 Other diseases of liver	0.000	0.988	0.012
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
K76.8 Other specified diseases of liver	0.000	0.989	0.011
N05.2 Diffuse membranous glomerulonephritis	0.011	0.989	0.000
K76.7 Hepatorenal syndrome	0.000	0.989	0.011
G43.9 Migraine, unspecified	0.011	0.989	0.000
N05.8 Other	0.011	0.989	0.000
N05.6 Dense deposit disease	0.010	0.990	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.010	0.990	0.000
N05.0 Minor glomerular abnormality	0.010	0.990	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.010	0.990	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.009	0.991	0.000
N00-N08 Glomerular diseases	0.009	0.991	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.991	0.008
K76.4 Peliosis hepatis	0.000	0.991	0.008
K76.3 Infarction of liver	0.000	0.991	0.008
K76.2 Central haemorrhagic necrosis of liver	0.000	0.991	0.008
K76.1 Chronic passive congestion of liver	0.000	0.991	0.008
N02 Recurrent and persistent haematuria	0.008	0.992	0.000
N02.9 Unspecified	0.008	0.992	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.008	0.992	0.000
K76.9 Liver disease, unspecified	0.000	0.992	0.008
N03 Chronic nephritic syndrome	0.008	0.992	0.000
N04 Nephrotic syndrome	0.007	0.993	0.000
N00 Acute nephritic syndrome	0.007	0.993	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.007	0.993	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.007	0.993	0.000
N06 Isolated proteinuria with specified morphological lesion	0.007	0.993	0.000
N01 Rapidly progressive nephritic syndrome	0.007	0.993	0.000
N03.8 Other	0.007	0.993	0.000
N02.0 Minor glomerular abnormality	0.006	0.993	0.000
K86.9 Disease of pancreas, unspecified	0.007	0.993	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.993	0.000
N04.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N02.6 Dense deposit disease	0.006	0.994	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N02.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N02.8 Other	0.006	0.994	0.000
G43 Migraine	0.006	0.994	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.994	0.006
N03.9 Unspecified	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.000	0.994	0.006
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N00.9 Unspecified	0.006	0.994	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N03.6 Dense deposit disease	0.006	0.994	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N03.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N03.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N03.0 Minor glomerular abnormality	0.006	0.994	0.000
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
N02.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N04.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.000
N04.8 Other	0.005	0.994	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.000
N04.6 Dense deposit disease	0.005	0.994	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.000
N04.0 Minor glomerular abnormality	0.005	0.994	0.000
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
N00.8 Other	0.005	0.995	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N00.6 Dense deposit disease	0.005	0.995	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N00.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
N00.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N00.0 Minor glomerular abnormality	0.005	0.995	0.000
R04.2 Haemoptysis	0.000	0.995	0.005
K86 Other diseases of pancreas	0.005	0.995	0.000
G43.1 Migraine with aura [classical migraine]	0.005	0.995	0.000
N01.9 Unspecified	0.005	0.995	0.000
N01.8 Other	0.005	0.995	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N01.6 Dense deposit disease	0.005	0.995	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N01.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
N01.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N01.0 Minor glomerular abnormality	0.005	0.995	0.000
N06.9 Unspecified	0.005	0.995	0.000
N06.8 Other	0.005	0.995	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N06.6 Dense deposit disease	0.005	0.995	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N06.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
N06.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N06.0 Minor glomerular abnormality	0.005	0.995	0.000
N07.9 Unspecified	0.005	0.995	0.000
N07.8 Other	0.005	0.995	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N07.6 Dense deposit disease	0.005	0.995	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N07.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
N07.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N07.0 Minor glomerular abnormality	0.005	0.995	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.995	0.005
M13.09 Polyarthritis, unspecified (Site unspecified)	0.005	0.995	0.000
G43.8 Other migraine	0.005	0.995	0.000
D68 Other coagulation defects	0.000	0.995	0.005
Z94.0 Kidney transplant status	0.005	0.995	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.995	0.005
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
N04.9 Unspecified	0.005	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
G43.2 Status migrainosus	0.005	0.995	0.000
G43.3 Complicated migraine	0.004	0.995	0.000
D68.0 Von Willebrand's disease	0.000	0.995	0.005
D69.4 Other primary thrombocytopenia	0.000	0.995	0.004
G43.0 Migraine without aura [common migraine]	0.004	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.004	0.995	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.995	0.005
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.004	0.996	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
K70 Alcoholic liver disease	0.000	0.996	0.004
M13.0 Polyarthritis, unspecified	0.004	0.996	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.004	0.996	0.000
Z57.7 Occupational exposure to vibration	0.004	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.004	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.004	0.996	0.000
Z57.1 Occupational exposure to radiation	0.004	0.996	0.000
Z57.0 Occupational exposure to noise	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.000	0.996	0.004
Y42.7 Androgens and anabolic congeners	0.000	0.996	0.004
K72.9 Hepatic failure, unspecified	0.000	0.996	0.004
K86.2 Cyst of pancreas	0.004	0.996	0.000
K70-K77 Diseases of liver	0.000	0.996	0.004
D69.0 Allergic purpura	0.000	0.996	0.004
D68.1 Hereditary factor XI deficiency	0.000	0.996	0.004
M13.06 Polyarthritis, unspecified (Lower leg)	0.004	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.996	0.004
K72 Hepatic failure, not elsewhere classified	0.000	0.996	0.004
C84.4 Peripheral T-cell lymphoma	0.000	0.996	0.004
D69.1 Qualitative platelet defects	0.000	0.996	0.004
K86.1 Other chronic pancreatitis	0.004	0.996	0.000
Z57.2 Occupational exposure to dust	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.996	0.004
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.996	0.004
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.997	0.003
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
N08 Glomerular disorders in diseases classified elsewhere	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.997	0.003
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.003	0.997	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.997	0.003
M13.08 Polyarthritis, unspecified (Other)	0.003	0.997	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.003	0.997	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.003	0.997	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.003	0.997	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.997	0.003
D69.9 Haemorrhagic condition, unspecified	0.000	0.997	0.003
H44.2 Degenerative myopia	0.000	0.997	0.003
K77 Liver disorders in diseases classified elsewhere	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.000	0.997	0.003
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.997	0.003
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.997	0.003
D67 Hereditary factor IX deficiency	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
N18.0 End-stage renal disease	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.997	0.003
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.997	0.003
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.997	0.003
Z94.7 Corneal transplant status	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.000	0.997	0.003
K72.1 Chronic hepatic failure	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.997	0.003
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.002	0.997	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.002	0.997	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.002	0.997	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.002	0.997	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.002	0.997	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
Z98.8 Other specified postsurgical states	0.000	0.997	0.003
S62.6 Fracture of other finger	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.002
O00.1 Tubal pregnancy	0.000	0.997	0.003
M19.02 Primary arthrosis of other joints (Upper arm)	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
S62.60 Fracture of other finger (closed)	0.000	0.997	0.003
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.997	0.003
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
C84.0 Mycosis fungoides	0.000	0.997	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.997	0.002
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.997	0.003
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.997	0.002
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.997	0.002
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.997	0.002
C84.3 Lymphoepithelioid lymphoma	0.000	0.997	0.002
C84.2 T-zone lymphoma	0.000	0.997	0.002
C84.1 Sezary's diease	0.000	0.997	0.002
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.002
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.997	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.997	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.997	0.003
K71 Toxic liver disease	0.000	0.997	0.002
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
K73 Chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
H44 Disorders of globe	0.000	0.998	0.002
Z94 Transplanted organ and tissue status	0.002	0.998	0.000
H44.0 Purulent endophthalmitis	0.000	0.998	0.002
K14.9 Disease of tongue, unspecified	0.000	0.998	0.002
O00.9 Ectopic pregnancy, unspecified	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.998	0.002
Z36.8 Other antenatal screening	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
H44.1 Other endophthalmitis	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.998	0.002
Z94.3 Heart and lungs transplant status	0.002	0.998	0.000
Z94.2 Lung transplant status	0.002	0.998	0.000
H44.4 Hypotony of eye	0.000	0.998	0.002
Z94.5 Skin transplant status	0.002	0.998	0.000
D35.0 Adrenal gland	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.000	0.998	0.002
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.002
K74.1 Hepatic sclerosis	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.002
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.002
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.002
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.002
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.002
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.002
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.998	0.002
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.998	0.002
N08.5 Glomerular disorders in systemic connective tissue disorders	0.001	0.998	0.001
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.002	0.998	0.000
Z94.6 Bone transplant status	0.002	0.998	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.002
H44.3 Other degenerative disorders of globe	0.000	0.998	0.002
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.002
O00 Ectopic pregnancy	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
Z94.1 Heart transplant status	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.002
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.000	0.998	0.002
H44.8 Other disorders of globe	0.000	0.998	0.002
Y83.4 Other reconstructive surgery	0.000	0.998	0.002
G46.7 Other lacunar syndromes	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
O00.8 Other ectopic pregnancy	0.000	0.998	0.002
O00.2 Ovarian pregnancy	0.000	0.998	0.002
O00.0 Abdominal pregnancy	0.000	0.998	0.002
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
K52.3 Indeterminate colitis	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
M79.88 Other specified soft tissue disorders (Other)	0.002	0.998	0.000
K75.0 Abscess of liver	0.000	0.998	0.002
G35 Multiple sclerosis	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
H44.5 Degenerated conditions of globe	0.000	0.998	0.001
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.001
K75.1 Phlebitis of portal vein	0.000	0.998	0.001
M19.01 Primary arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.998	0.002
M46.4 Discitis, unspecified	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.998	0.001
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.002
M19.08 Primary arthrosis of other joints (Other)	0.001	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.001	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.001
V49 Car occupant injured in other and unspecified transport accidents	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.001
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.998	0.001
I87.1 Compression of vein	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.001
M46.44 Discitis, unspecified (Thoracic region)	0.001	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.001
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.999	0.001
S05.9 Injury of eye and orbit, part unspecified	0.000	0.999	0.001
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.999	0.001
C97 Malignant neoplasms of independent (primary) multiple sites	0.001	0.999	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.999	0.001
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.999	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.999	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M46.42 Discitis, unspecified (Cervical region)	0.001	0.999	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.999	0.001
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
S62.71 Multiple fractures of fingers (open)	0.000	0.999	0.001
C90.3 Solitary plasmacytoma	0.000	0.999	0.001
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.001	0.999	0.001
O36.3 Maternal care for signs of foetal hypoxia	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.001	0.999	0.000
V49.8 Car occupant [any] injured in other specified transport accidents	0.000	0.999	0.001
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.999	0.001
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.000	0.999	0.001
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.999	0.001
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.999	0.001
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.999	0.001
X78.0 Home	0.000	0.999	0.001
S62.70 Multiple fractures of fingers (closed)	0.000	0.999	0.001
S22.40 Multiple fractures of ribs (closed)	0.001	0.999	0.000
G81.9 Hemiplegia, unspecified	0.000	0.999	0.001
K31.5 Obstruction of duodenum	0.001	0.999	0.000
M21.7 Unequal limb length (acquired)	0.001	0.999	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.999	0.001
Z01.6 Radiological examination, not elsewhere classified	0.000	0.999	0.001
M19.03 Primary arthrosis of other joints (Forearm)	0.001	0.999	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.999	0.001
A04.8 Other specified bacterial intestinal infections	0.000	0.999	0.001
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.999	0.001
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.999	0.001
C90.1 Plasma cell leukaemia	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.001	0.999	0.001
S62.5 Fracture of thumb	0.000	0.999	0.001
T21.1 Burn of first degree of trunk	0.001	0.999	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.001	0.999	0.000
Z93.1 Gastrostomy status	0.001	0.999	0.000
Z96.8 Presence of other specified functional implants	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.999	0.001
K74.0 Hepatic fibrosis	0.000	0.999	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.001	0.999	0.000
T21 Burn and corrosion of trunk	0.001	0.999	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.999	0.001
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.999	0.000
M21.6 Other acquired deformities of ankle and foot	0.001	0.999	0.000
O36.5 Maternal care for poor foetal growth	0.001	0.999	0.000
V49.81 Car occupant injured in trnsp accident w military vehicle (Car occupant (driver) (passenger) injured in transport accident with military vehicle)	0.000	0.999	0.001
H18.7 Other corneal deformities	0.001	0.999	0.000
I84.0 Internal thrombosed haemorrhoids	0.001	0.999	0.000
N50.1 Vascular disorders of male genital organs	0.001	0.999	0.000
I87 Other disorders of veins	0.001	0.999	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.999	0.000
M21.78 Unequal limb length (acquired)-Other	0.001	0.999	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.999	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.999	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.999	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.999	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.999	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.999	0.000
L12.1 Cicatricial pemphigoid	0.000	0.999	0.001
Z94.4 Liver transplant status	0.001	0.999	0.000
Z96.2 Presence of otological and audiological implants	0.001	0.999	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.999	0.001
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.999	0.001
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
R61.1 Generalised hyperhidrosis	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
W01.6 Industrial and construction area	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
M19.09 Primary arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.001	0.999	0.000
H18.2 Other corneal oedema	0.001	0.999	0.000
L12.0 Bullous pemphigoid	0.000	0.999	0.001
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.999	0.001
T21.7 Corrosion of third degree of trunk	0.001	0.999	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.999	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.999	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.999	0.000
T45.5 Anticoagulants	0.000	0.999	0.001
H18 Other disorders of cornea	0.001	0.999	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.999	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.999	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.999	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.999	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.999	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.999	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.999	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.999	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.999	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.999	0.001
D36.7 Other specified sites	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.001	0.999	0.000
G58.8 Other specified mononeuropathies	0.001	0.999	0.000
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
F00 Dementia in Alzheimer's disease	0.001	0.999	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.999	0.001
I87.9 Disorder of vein, unspecified	0.001	0.999	0.000
I87.0 Postphlebitic syndrome	0.001	0.999	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.001	0.999	0.000
W01.1 Residential institution	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.999	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.999	0.001
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.999	0.001
S05.8 Other injuries of eye and orbit	0.000	0.999	0.001
I69 Sequelae of cerebrovascular disease	0.000	0.999	0.001
R61 Hyperhidrosis	0.001	0.999	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
R23.2 Flushing	0.001	0.999	0.000
R23.0 Cyanosis	0.001	0.999	0.000
R61.0 Localised hyperhidrosis	0.001	0.999	0.000
Z52.0 Blood donor	0.001	0.999	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.999	0.001
H18.3 Changes in corneal membranes	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.999	0.001
T21.3 Burn of third degree of trunk	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations