TreeWAS – Variant ID: rs9561428

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F17.1 Harmful use	0.000	0.992	0.008
K70.9 Alcoholic liver disease, unspecified	0.005	0.995	0.000
J22 Unspecified acute lower respiratory infection	0.000	0.995	0.005
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.995	0.005
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.997	0.003
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.997	0.003
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
S82.6 Fracture of lateral malleolus	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.000	0.997	0.003
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.997	0.003
K70.4 Alcoholic hepatic failure	0.003	0.997	0.000
K25 Gastric ulcer	0.000	0.997	0.003
M47.8 Other spondylosis	0.000	0.997	0.003
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F17.8 Other mental and behavioural disorders	0.000	0.997	0.003
F17.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F17.6 Amnesic syndrome	0.000	0.997	0.003
F17.5 Psychotic disorder	0.000	0.997	0.003
F17.4 Withdrawal state with delirium	0.000	0.997	0.003
F17.3 Withdrawal state	0.000	0.997	0.003
F17.0 Acute intoxication	0.000	0.997	0.003
M47 Spondylosis	0.000	0.997	0.003
K25.7 Chronic without haemorrhage or perforation	0.000	0.997	0.003
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.003
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.997	0.003
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.997	0.000
K70.1 Alcoholic hepatitis	0.002	0.997	0.000
K70.0 Alcoholic fatty liver	0.002	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.997	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.997	0.000
Y44.2 Anticoagulants	0.002	0.997	0.000
I73 Other peripheral vascular diseases	0.002	0.997	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.997	0.002
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.997	0.002
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.998	0.002
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
D70 Agranulocytosis	0.002	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
K25.5 Chronic or unspecified with perforation	0.000	0.998	0.002
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
K25.2 Acute with both haemorrhage and perforation	0.000	0.998	0.002
K25.1 Acute with perforation	0.000	0.998	0.002
K25.0 Acute with haemorrhage	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.998	0.002
M47.84 Other spondylosis (Thoracic region)	0.000	0.998	0.002
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.998	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.998	0.002
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
I77 Other disorders of arteries and arterioles	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.998	0.002
R07.4 Chest pain, unspecified	0.000	0.998	0.002
Y43 Primarily systemic agents	0.002	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.998	0.002
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.998	0.002
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.998	0.002
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.998	0.002
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.998	0.002
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.998	0.002
I77.1 Stricture of artery	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.998	0.002
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.998	0.002
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.998	0.002
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.998	0.002
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.998	0.002
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.998	0.002
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.998	0.002
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.998	0.002
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.998	0.002
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.998	0.002
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.998	0.002
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.998	0.002
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.998	0.002
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.998	0.002
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
J20-J22 Other acute lower respiratory infections	0.000	0.998	0.002
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
S82.0 Fracture of patella	0.001	0.998	0.000
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Z22 Carrier of infectious disease	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
Z88.2 Personal history of allergy to sulphonamides	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.001	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.001	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.001	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.001	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.6 Other diagnostic agents	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Y41.5 Antiviral drugs	0.001	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Y41.0 Sulphonamides	0.001	0.998	0.000
Y45.0 Opioids and related analgesics	0.001	0.998	0.000
Y46.8 Antispasticity drugs	0.001	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
Y46.5 Valproic acid	0.001	0.998	0.000
Y46.4 Iminostilbenes	0.001	0.998	0.000
Y46.3 Deoxybarbiturates	0.001	0.998	0.000
Y46.2 Hydantoin derivatives	0.001	0.998	0.000
Y46.1 Oxazolidinediones	0.001	0.998	0.000
Y46.0 Succinimides	0.001	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
Y48.3 Local anaesthetics	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
Y54.7 Agents affecting calcification	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.5 Other diuretics	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.998	0.000
M45-M49 Spondylopathies	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.001	0.998	0.000
Y95 Nosocomial condition	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
M45 Ankylosing spondylitis	0.000	0.998	0.001
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
I78 Diseases of capillaries	0.001	0.998	0.001
S82.11 Fracture of upper end of tibia (open)	0.001	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.001	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
Y42.4 Oral contraceptives	0.001	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.000
Y42.2 Antithyroid drugs	0.001	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.998	0.000
J21 Acute bronchiolitis	0.000	0.998	0.001
S82.01 Fracture of patella (open)	0.001	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.001	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.001
Z22.9 Carrier of infectious disease, unspecified	0.001	0.998	0.000
Z22.8 Carrier of other infectious diseases	0.001	0.998	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.001	0.998	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.001	0.998	0.000
Z22.2 Carrier of diphtheria	0.001	0.998	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.001	0.998	0.000
Z22.0 Carrier of typhoid	0.001	0.998	0.000
A49 Bacterial infection of unspecified site	0.001	0.998	0.000
M46 Other inflammatory spondylopathies	0.000	0.998	0.001
S82.50 Fracture of medial malleolus (closed)	0.001	0.998	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.002	0.998	0.000
N94.4 Primary dysmenorrhoea	0.001	0.998	0.000
I70 Atherosclerosis	0.001	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.001	0.999	0.000
A49.9 Bacterial infection, unspecified	0.001	0.999	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
I72.0 Aneurysm of carotid artery	0.001	0.999	0.000
J02 Acute pharyngitis	0.000	0.999	0.001
S80-S89 Injuries to the knee and lower leg	0.001	0.999	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.001	0.999	0.000
M49 Spondylopathies in diseases classified elsewhere	0.000	0.999	0.001
M48 Other spondylopathies	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
I79.1 Aortitis in diseases classified elsewhere	0.001	0.999	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.001	0.999	0.000
Y42.7 Androgens and anabolic congeners	0.001	0.999	0.000
I73.0 Raynaud's syndrome	0.001	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
T42.4 Benzodiazepines	0.001	0.999	0.000
I71 Aortic aneurysm and dissection	0.001	0.999	0.000
J20 Acute bronchitis	0.000	0.999	0.001
A41.8 Other specified septicaemia	0.001	0.999	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.999	0.001
I71.0 Dissection of aorta [any part]	0.001	0.999	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.999	0.001
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.999	0.001
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.999	0.001
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.999	0.001
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.999	0.001
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.999	0.001
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
O34.1 Maternal care for tumour of corpus uteri	0.001	0.999	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.999	0.001
I78.8 Other diseases of capillaries	0.001	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.001	0.999	0.001
O32.1 Maternal care for breech presentation	0.001	0.999	0.000
Y42.5 Other oestrogens and progestogens	0.001	0.999	0.000
Z01.6 Radiological examination, not elsewhere classified	0.001	0.999	0.000
A41 Other septicaemia	0.001	0.999	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.001	0.999	0.000
J21.9 Acute bronchiolitis, unspecified	0.000	0.999	0.001
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.999	0.001
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.999	0.001
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.999	0.001
N94.3 Premenstrual tension syndrome	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
A41.9 Septicaemia, unspecified	0.001	0.999	0.000
A49.3 Mycoplasma infection, unspecified	0.001	0.999	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.001	0.999	0.000
A49.1 Streptococcal infection, unspecified	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.001	0.999	0.000
I70.8 Atherosclerosis of other arteries	0.001	0.999	0.000
I70.1 Atherosclerosis of renal artery	0.001	0.999	0.000
I70.0 Atherosclerosis of aorta	0.001	0.999	0.000
M46.8 Other specified inflammatory spondylopathies	0.000	0.999	0.001
M46.5 Other infective spondylopathies	0.000	0.999	0.001
M46.4 Discitis, unspecified	0.000	0.999	0.001
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.999	0.001
M46.2 Osteomyelitis of vertebra	0.000	0.999	0.001
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.999	0.001
M46.0 Spinal enthesopathy	0.000	0.999	0.001
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.999	0.001
J02.0 Streptococcal pharyngitis	0.000	0.999	0.001
N94.5 Secondary dysmenorrhoea	0.001	0.999	0.000
N94.2 Vaginismus	0.001	0.999	0.000
N94.0 Mittelschmerz	0.001	0.999	0.000
S89 Other and unspecified injuries of lower leg	0.001	0.999	0.000
S88 Traumatic amputation of lower leg	0.001	0.999	0.000
S87 Crushing injury of lower leg	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
S85 Injury of blood vessels at lower leg level	0.001	0.999	0.000
S84 Injury of nerves at lower leg level	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
S82.10 Fracture of upper end of tibia (closed)	0.001	0.999	0.000
M48.9 Spondylopathy, unspecified	0.000	0.999	0.001
M48.8 Other specified spondylopathies	0.000	0.999	0.001
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.999	0.001
M48.4 Fatigue fracture of vertebra	0.000	0.999	0.001
M48.3 Traumatic spondylopathy	0.000	0.999	0.001
M48.2 Kissing spine	0.000	0.999	0.001
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.999	0.001
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.999	0.001
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.999	0.001
M49.4 Neuropathic spondylopathy	0.000	0.999	0.001
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
M49.2 Enterobacterial spondylitis	0.000	0.999	0.001
M49.1 Brucella spondylitis	0.000	0.999	0.001
M49.0 Tuberculosis of spine	0.000	0.999	0.001
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
T51.0 Ethanol	0.001	0.999	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.999	0.001
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.999	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
J20.8 Acute bronchitis due to other specified organisms	0.000	0.999	0.001
J20.7 Acute bronchitis due to echovirus	0.000	0.999	0.001
J20.6 Acute bronchitis due to rhinovirus	0.000	0.999	0.001
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.999	0.001
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.999	0.001
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations